GREMLIN Database
Q9HPM3 - Protoporphyrin IX magnesium chelatase
UniProt: Q9HPM3 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 690 (640)
Sequences: 353 (280)
Seq/√Len: 11.1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
471_G474_V6.1631.00
442_V445_D5.4531.00
442_V447_D5.1601.00
475_R479_A4.5481.00
471_G475_R4.3371.00
75_C79_C4.0860.99
443_A447_D3.9800.99
474_V478_R3.9430.99
555_I578_A3.9190.99
23_V58_T3.9190.99
88_C91_C3.9050.99
217_S281_H3.8150.99
471_G476_T3.7220.99
521_V556_A3.7150.99
637_S665_A3.6750.98
445_D450_D3.5630.98
474_V479_A3.5490.98
241_D244_A3.4320.98
347_D351_D3.2680.97
86_R89_A3.2290.96
639_L681_V3.2210.96
19_P22_A3.1850.96
475_R478_R3.1460.96
441_G447_D3.1170.96
86_R90_D3.1000.95
85_T88_C3.0990.95
472_A475_R3.0420.95
87_Q90_D3.0250.95
438_P441_G2.9390.94
294_L310_R2.7610.92
79_C88_C2.7380.91
441_G445_D2.7190.91
42_L61_A2.6720.90
75_C88_C2.6590.90
556_A604_L2.6270.89
476_T479_A2.6190.89
442_V446_A2.6060.89
668_G671_V2.5520.88
83_D86_R2.4970.87
601_D642_R2.4730.86
536_A539_G2.4480.86
338_H342_D2.4290.85
86_R91_C2.4250.85
300_R538_K2.3870.84
118_V238_Y2.3850.84
436_V445_D2.3610.83
463_A513_A2.3310.83
483_D509_Q2.3130.82
438_P445_D2.3070.82
447_D450_D2.2840.81
85_T89_A2.2560.80
446_A450_D2.2250.79
374_E379_T2.2220.79
221_A267_R2.1840.78
409_P417_D2.1780.78
283_A548_A2.1310.76
438_P442_V2.0990.75
436_V443_A2.0650.74
134_F292_R2.0590.74
442_V450_D2.0580.74
265_L268_E1.9930.71
639_L644_A1.9890.71
509_Q578_A1.9880.71
602_D605_A1.9830.71
275_D338_H1.9690.70
85_T90_D1.9580.70
83_D90_D1.9540.70
271_E668_G1.9490.69
538_K586_P1.9480.69
118_V556_A1.9380.69
443_A446_A1.9150.68
30_K281_H1.9060.68
441_G444_P1.8760.66
444_P447_D1.8710.66
470_R474_V1.8700.66
557_V617_V1.8650.66
441_G450_D1.8560.65
526_A534_M1.8240.64
601_D681_V1.8100.63
521_V604_L1.8060.63
29_L38_A1.8010.63
393_Q427_V1.7820.62
174_V558_V1.7800.62
262_P265_L1.7720.62
523_A600_A1.7660.61
436_V440_T1.7400.60
298_D586_P1.7140.59
429_G445_D1.7130.59
220_I546_R1.7090.59
439_G445_D1.7080.59
83_D88_C1.7080.59
526_A569_V1.6920.58
423_A426_L1.6670.57
656_R659_T1.6610.56
87_Q91_C1.6600.56
134_F610_D1.6440.56
72_V79_C1.6370.55
438_P443_A1.6250.55
534_M538_K1.6200.54
443_A450_D1.6140.54
49_G55_K1.6100.54
616_V662_I1.6100.54
285_V517_S1.6020.54
611_A651_A1.5730.52
534_M586_P1.5540.51
26_Q30_K1.5390.51
533_P540_V1.5290.50
436_V441_G1.5280.50
287_T315_A1.5160.49
327_D546_R1.5140.49
300_R586_P1.5130.49
433_G442_V1.5100.49
384_A403_S1.4970.49
352_A414_R1.4940.48
438_P447_D1.4930.48
634_T641_E1.4930.48
157_D278_V1.4900.48
372_D377_G1.4880.48
380_G405_A1.4870.48
360_G405_A1.4810.48
390_D407_D1.4770.48
407_D416_D1.4770.48
239_A243_A1.4750.47
114_S118_V1.4740.47
49_G52_G1.4590.47
52_G55_K1.4590.47
672_P675_A1.4530.46
545_L574_S1.4480.46
72_V75_C1.4440.46
534_M542_L1.4420.46
375_P408_D1.4420.46
579_A586_P1.4380.46
104_V123_S1.4340.46
265_L308_I1.4220.45
472_A476_T1.4200.45
151_E194_N1.4150.45
83_D89_A1.4110.44
162_V661_D1.4090.44
132_A135_S1.4090.44
347_D352_A1.4060.44
47_V548_A1.4040.44
400_P419_D1.3980.44
349_E353_E1.3800.43
513_A517_S1.3740.43
118_V577_L1.3740.43
357_E415_G1.3670.42
418_E425_P1.3560.42
156_D513_A1.3560.42
161_D165_D1.3560.42
36_V177_D1.3530.42
446_A449_P1.3510.42
281_H492_R1.3470.41
631_A635_A1.3460.41
594_P632_T1.3450.41
437_E504_S1.3390.41
341_D446_A1.3370.41
135_S538_K1.3320.41
440_T447_D1.3310.41
165_D273_C1.3310.41
433_G443_A1.3180.40
85_T91_C1.3160.40
389_P408_D1.3070.40
135_S509_Q1.3030.39
632_T639_L1.3030.39
438_P450_D1.3010.39
224_V491_V1.3000.39
451_A455_T1.2990.39
345_Q349_E1.2970.39
473_R477_E1.2940.39
557_V578_A1.2920.39
70_R254_D1.2880.39
156_D162_V1.2850.39
105_P108_T1.2840.38
114_S177_D1.2840.38
668_G681_V1.2820.38
247_D616_V1.2800.38
471_G479_A1.2790.38
439_G442_V1.2730.38
469_A483_D1.2730.38
294_L595_A1.2710.38
354_T375_P1.2640.38
287_T546_R1.2590.37
655_A659_T1.2450.37
438_P444_P1.2420.37
334_V338_H1.2380.36
272_L532_G1.2340.36
157_D201_R1.2320.36
205_R533_P1.2290.36
118_V584_D1.2230.36
455_T535_R1.2140.35
300_R307_D1.2070.35
171_V610_D1.2070.35
127_A617_V1.2050.35
58_T298_D1.2050.35
513_A554_E1.2040.35
452_E456_G1.2010.35
221_A523_A1.1980.35
221_A224_V1.1900.34
433_G436_V1.1900.34
595_A676_L1.1890.34
373_A377_G1.1880.34
434_D442_V1.1870.34
271_E285_V1.1860.34
540_V543_D1.1850.34
21_P255_L1.1830.34
395_E414_R1.1800.34
492_R538_K1.1790.34
56_S169_S1.1790.34
349_E387_G1.1760.34
474_V505_R1.1760.34
458_S481_P1.1740.34
333_D420_T1.1700.33
536_A676_L1.1690.33
452_E455_T1.1630.33
149_V472_A1.1540.33
462_S518_A1.1500.33
83_D375_P1.1500.33
63_A653_D1.1420.32
439_G447_D1.1400.32
104_V141_A1.1370.32
335_V339_F1.1340.32
387_G418_E1.1280.32
40_A43_D1.1210.31
403_S408_D1.1160.31
422_D428_P1.1150.31
149_V281_H1.1150.31
360_G378_D1.1130.31
390_D402_D1.1100.31
549_Y552_R1.1080.31
305_E308_I1.1080.31
386_T393_Q1.1070.31
382_A394_S1.1060.31
439_G443_A1.1040.31
306_A634_T1.1010.31
659_T662_I1.1000.30
219_E332_E1.0990.30
214_V649_V1.0960.30
648_V652_G1.0940.30
346_S617_V1.0940.30
118_V277_G1.0910.30
355_S359_G1.0870.30
75_C81_P1.0840.30
159_L284_D1.0830.30
69_Q78_G1.0810.30
584_D637_S1.0810.30
219_E389_P1.0790.30
243_A247_D1.0790.30
403_S423_A1.0780.30
213_A542_L1.0770.30
29_L58_T1.0760.30
278_V284_D1.0730.29
125_T308_I1.0710.29
668_G676_L1.0710.29
545_L578_A1.0620.29
233_G414_R1.0590.29
399_A408_D1.0580.29
255_L301_P1.0570.29
470_R476_T1.0550.29
356_D359_G1.0550.29
161_D203_Q1.0550.29
42_L242_T1.0540.29
437_E443_A1.0530.29
30_K123_S1.0530.29
633_R639_L1.0530.29
265_L546_R1.0520.29
440_T449_P1.0500.28
405_A428_P1.0480.28
157_D161_D1.0480.28
72_V81_P1.0460.28
388_G392_S1.0430.28
129_A281_H1.0390.28
416_D426_L1.0390.28
632_T636_A1.0370.28
399_A402_D1.0360.28
437_E447_D1.0350.28
400_P406_G1.0330.28
534_M560_F1.0310.28
220_I346_S1.0290.28
241_D246_R1.0270.28
141_A185_A1.0240.27
308_I676_L1.0220.27
644_A670_R1.0200.27
356_D407_D1.0180.27
663_V670_R1.0170.27
454_A460_R1.0090.27
399_A411_D1.0070.27
509_Q538_K1.0070.27
283_A526_A1.0070.27
312_A569_V1.0020.27
30_K172_N0.9990.27
664_D667_D0.9980.26
173_R323_R0.9970.26
639_L645_H0.9970.26
35_A40_A0.9950.26
322_S325_F0.9950.26
36_V238_Y0.9930.26
122_L184_P0.9920.26
313_G485_V0.9920.26
272_L287_T0.9910.26
255_L677_S0.9910.26
171_V290_A0.9890.26
310_R489_A0.9880.26
112_G128_L0.9820.26
146_I458_S0.9820.26
399_A404_E0.9810.26
413_E416_D0.9810.26
69_Q517_S0.9780.26
154_L197_E0.9770.26
124_V171_V0.9740.26
262_P624_A0.9740.26
183_H569_V0.9740.26
535_R671_V0.9720.26
165_D168_A0.9710.25
246_R505_R0.9700.25
437_E446_A0.9700.25
631_A639_L0.9690.25
469_A509_Q0.9670.25
454_A462_S0.9660.25
676_L681_V0.9650.25
340_D426_L0.9650.25
160_V201_R0.9640.25
528_A533_P0.9630.25
355_S360_G0.9590.25
473_R488_A0.9590.25
149_V217_S0.9570.25
542_L579_A0.9550.25
246_R491_V0.9530.25
416_D427_V0.9530.25
161_D201_R0.9520.25
634_T638_A0.9510.25
51_K590_R0.9510.25
492_R500_D0.9490.25
410_T413_E0.9460.25
149_V548_A0.9460.25
432_R450_D0.9450.25
632_T635_A0.9420.24
161_D273_C0.9410.24
168_A203_Q0.9410.24
565_A572_T0.9410.24
402_D406_G0.9390.24
401_A418_E0.9370.24
147_L198_G0.9370.24
71_A144_R0.9350.24
393_Q402_D0.9330.24
32_G45_L0.9320.24
409_P558_V0.9320.24
165_D203_Q0.9300.24
659_T663_V0.9300.24
601_D669_E0.9280.24
99_V473_R0.9270.24
423_A438_P0.9260.24
402_D418_E0.9260.24
436_V442_V0.9240.24
65_L492_R0.9240.24
358_A427_V0.9230.24
105_P375_P0.9220.24
313_G631_A0.9210.24
451_A638_A0.9210.24
558_V566_D0.9200.24
47_V111_L0.9170.24
522_F586_P0.9170.24
125_T129_A0.9100.23
543_D678_A0.9080.23
476_T629_T0.9060.23
154_L198_G0.9060.23
241_D409_P0.9030.23
215_A323_R0.9030.23
440_T443_A0.9030.23
466_S470_R0.8960.23
386_T392_S0.8940.23
389_P414_R0.8910.23
525_D529_S0.8900.23
483_D532_G0.8890.23
381_G405_A0.8890.23
177_D488_A0.8880.23
489_A492_R0.8870.23
38_A308_I0.8870.23
491_V501_A0.8840.22
401_A408_D0.8840.22
224_V270_A0.8830.22
211_R604_L0.8830.22
81_P144_R0.8830.22
219_E348_E0.8820.22
258_D681_V0.8820.22
378_D394_S0.8790.22
224_V672_P0.8790.22
277_G310_R0.8790.22
574_S578_A0.8770.22
48_T518_A0.8760.22
348_E351_D0.8760.22
121_S274_R0.8750.22
219_E409_P0.8750.22
357_E414_R0.8740.22
659_T666_A0.8720.22
213_A602_D0.8720.22
408_D417_D0.8710.22
471_G478_R0.8700.22
379_T391_D0.8690.22
114_S217_S0.8680.22
539_G601_D0.8680.22
635_A681_V0.8680.22
512_N575_V0.8680.22
349_E564_D0.8670.22
400_P405_A0.8660.22
119_V676_L0.8660.22
484_D488_A0.8640.22
373_A379_T0.8640.22
34_L47_V0.8630.22
560_F591_T0.8630.22
386_T390_D0.8610.22
42_L290_A0.8550.21
436_V450_D0.8550.21
173_R268_E0.8530.21
473_R510_S0.8520.21
406_G415_G0.8510.21
298_D310_R0.8500.21
567_V603_V0.8500.21
26_Q134_F0.8500.21
386_T389_P0.8490.21
559_A568_L0.8490.21
582_L621_Q0.8480.21
393_Q405_A0.8460.21
509_Q557_V0.8460.21
395_E411_D0.8450.21
392_S401_A0.8450.21
491_V576_A0.8440.21
373_A392_S0.8420.21
224_V290_A0.8410.21
469_A472_A0.8380.21
262_P304_T0.8380.21
158_H203_Q0.8370.21
353_E381_G0.8370.21
528_A589_D0.8370.21
486_D510_S0.8370.21
240_A432_R0.8360.21
135_S300_R0.8360.21
156_D463_A0.8360.21
221_A340_D0.8350.21
432_R440_T0.8350.21
290_A455_T0.8340.21
63_A106_F0.8330.21
99_V646_V0.8330.21
244_A407_D0.8300.21
146_I222_D0.8300.21
349_E436_V0.8300.21
352_A376_D0.8290.21
161_D269_I0.8280.21
30_K535_R0.8270.21
78_G105_P0.8270.21
528_A540_V0.8260.21
145_G278_V0.8240.20
522_F545_L0.8230.20
347_D350_G0.8230.20
119_V668_G0.8170.20
346_S352_A0.8160.20
346_S350_G0.8160.20
396_G409_P0.8150.20
511_I534_M0.8150.20
459_G462_S0.8140.20
400_P416_D0.8120.20
276_A554_E0.8120.20
164_L180_S0.8110.20
599_A602_D0.8110.20
265_L586_P0.8110.20
436_V483_D0.8110.20
333_D396_G0.8090.20
220_I327_D0.8090.20
391_D422_D0.8090.20
240_A412_G0.8070.20
407_D437_E0.8060.20
636_A639_L0.8060.20
470_R478_R0.8050.20
72_V181_V0.8040.20
251_T387_G0.8030.20
240_A664_D0.7990.20
164_L167_A0.7980.20
292_R576_A0.7970.20
344_D436_V0.7970.20
58_T146_I0.7970.20
377_G382_A0.7970.20
423_A563_D0.7960.20
512_N603_V0.7950.20
23_V239_A0.7950.20
520_V643_G0.7930.20
72_V88_C0.7930.20
157_D203_Q0.7930.20
670_R677_S0.7920.19
143_N183_H0.7910.19
149_V183_H0.7910.19
550_Q587_T0.7910.19
123_S536_A0.7880.19
156_D211_R0.7880.19
86_R399_A0.7870.19
229_R561_A0.7870.19
87_Q97_P0.7840.19
153_N198_G0.7820.19
390_D393_Q0.7790.19
633_R665_A0.7790.19
407_D412_G0.7790.19
359_G417_D0.7770.19
348_E376_D0.7770.19
431_P434_D0.7760.19
73_A101_S0.7750.19
383_E393_Q0.7750.19
26_Q265_L0.7740.19
402_D416_D0.7720.19
182_T294_L0.7720.19
435_T445_D0.7680.19
389_P432_R0.7670.19
35_A43_D0.7660.19
433_G440_T0.7650.19
65_L222_D0.7640.19
377_G402_D0.7640.19
286_A320_L0.7640.19
525_D619_D0.7640.19
527_S619_D0.7640.19
529_S619_D0.7640.19
310_R313_G0.7610.19
415_G428_P0.7610.19
158_H167_A0.7600.19
126_D496_A0.7580.18
521_V560_F0.7570.18
38_A42_L0.7550.18
526_A545_L0.7540.18
161_D202_P0.7510.18
47_V173_R0.7500.18
662_I667_D0.7500.18
509_Q631_A0.7490.18
559_A569_V0.7490.18
146_I305_E0.7480.18
506_D572_T0.7470.18
376_D441_G0.7470.18
240_A411_D0.7460.18
238_Y580_R0.7440.18
401_A425_P0.7440.18
519_L609_P0.7440.18
173_R188_T0.7430.18
191_G197_E0.7420.18
351_D358_A0.7420.18
77_Y556_A0.7400.18
545_L572_T0.7380.18
34_L381_G0.7370.18
118_V188_T0.7370.18
352_A384_A0.7350.18
225_E603_V0.7350.18
158_H201_R0.7350.18
265_L327_D0.7350.18
68_D101_S0.7350.18
403_S416_D0.7340.18
43_D209_A0.7340.18
153_N193_M0.7340.18
386_T634_T0.7330.18
558_V567_V0.7320.18
256_L259_V0.7310.18
161_D167_A0.7300.18
421_E426_L0.7300.18
127_A556_A0.7300.18
133_E271_E0.7280.18
287_T586_P0.7280.18
119_V509_Q0.7280.18
265_L338_H0.7270.18
82_E567_V0.7270.18
385_P391_D0.7250.18
674_D677_S0.7210.17
401_A584_D0.7210.17
74_D427_V0.7210.17
124_V334_V0.7200.17
167_A191_G0.7190.17
240_A388_G0.7190.17
108_T111_L0.7190.17
351_D407_D0.7190.17
192_T197_E0.7180.17
433_G438_P0.7180.17
171_V595_A0.7170.17
257_P479_A0.7170.17
279_D551_H0.7170.17
36_V129_A0.7170.17
393_Q437_E0.7160.17
171_V246_R0.7150.17
221_A387_G0.7150.17
455_T465_P0.7140.17
485_V624_A0.7140.17
348_E436_V0.7120.17
484_D680_R0.7090.17
254_D558_V0.7080.17
254_D417_D0.7060.17
114_S268_E0.7060.17
161_D284_D0.7060.17
254_D358_A0.7060.17
323_R458_S0.7050.17
300_R304_T0.7050.17
358_A422_D0.7050.17
23_V290_A0.7050.17
395_E404_E0.7040.17
532_G646_V0.7030.17
121_S294_L0.7010.17
381_G384_A0.7000.17
251_T255_L0.6980.17
566_D584_D0.6960.17
123_S587_T0.6960.17
37_A62_L0.6940.17
134_F333_D0.6940.17
260_D641_E0.6940.17
405_A415_G0.6930.17
661_D664_D0.6930.17
323_R586_P0.6910.17
358_A400_P0.6900.17
389_P393_Q0.6880.17
243_A361_D0.6870.17
133_E246_R0.6870.17
337_D576_A0.6860.16
189_L203_Q0.6850.16
464_T473_R0.6850.16
406_G423_A0.6850.16
43_D293_T0.6820.16
182_T327_D0.6810.16
191_G203_Q0.6810.16
443_A449_P0.6800.16
138_L284_D0.6790.16
473_R484_D0.6770.16
653_D679_D0.6760.16
380_G406_G0.6740.16
401_A406_G0.6740.16
390_D416_D0.6740.16
395_E427_V0.6730.16
472_A479_A0.6730.16
298_D338_H0.6720.16
124_V294_L0.6720.16
360_G390_D0.6720.16
129_A292_R0.6710.16
436_V444_P0.6700.16
510_S623_N0.6700.16
403_S422_D0.6690.16
557_V681_V0.6690.16
144_R174_V0.6680.16
23_V298_D0.6680.16
80_P84_P0.6670.16
406_G630_A0.6660.16
555_I593_L0.6660.16
361_D381_G0.6660.16
276_A548_A0.6650.16
405_A424_A0.6650.16
539_G676_L0.6650.16
111_L297_L0.6640.16
432_R438_P0.6620.16
376_D445_D0.6610.16
432_R445_D0.6610.16
311_A317_P0.6610.16
75_C489_A0.6580.16
32_G42_L0.6580.16
219_E669_E0.6580.16
404_E411_D0.6570.16
275_D285_V0.6570.16
75_C123_S0.6560.16
152_V203_Q0.6550.16
182_T222_D0.6550.16
168_A202_P0.6540.16
380_G388_G0.6530.16
171_V182_T0.6530.16
193_M591_T0.6530.16
384_A439_G0.6520.16
333_D388_G0.6520.16
301_P634_T0.6520.16
132_A477_E0.6510.16
163_L600_A0.6510.16
262_P502_V0.6500.16
356_D417_D0.6500.16
401_A424_A0.6500.16
27_D30_K0.6490.16
489_A573_D0.6490.16
250_V258_D0.6490.16
380_G409_P0.6480.15
523_A558_V0.6450.15
409_P415_G0.6440.15
65_L178_G0.6440.15
327_D580_R0.6440.15
546_R586_P0.6420.15
436_V447_D0.6410.15
567_V606_R0.6410.15
664_D680_R0.6380.15
358_A361_D0.6370.15
260_D305_E0.6370.15
352_A420_T0.6370.15
231_L681_V0.6360.15
260_D444_P0.6360.15
100_E408_D0.6330.15
125_T606_R0.6320.15
159_L273_C0.6320.15
99_V256_L0.6300.15
34_L225_E0.6300.15
121_S677_S0.6290.15
456_G462_S0.6280.15
123_S589_D0.6270.15
392_S427_V0.6260.15
405_A410_T0.6260.15
396_G410_T0.6260.15
269_I273_C0.6250.15
98_P355_S0.6240.15
298_D538_K0.6230.15
81_P127_A0.6230.15
439_G446_A0.6220.15
149_V156_D0.6220.15
51_K59_A0.6220.15
375_P382_A0.6210.15
599_A669_E0.6190.15
635_A638_A0.6180.15
401_A411_D0.6180.15
158_H202_P0.6180.15
478_R617_V0.6170.15
376_D380_G0.6170.15
402_D430_Q0.6170.15
209_A652_G0.6160.15
354_T360_G0.6160.15
408_D661_D0.6160.15
160_V203_Q0.6160.15
542_L560_F0.6150.15
161_D278_V0.6150.15
281_H489_A0.6140.15
466_S501_A0.6140.15
119_V132_A0.6140.15
272_L644_A0.6130.15
115_R589_D0.6130.15
21_P242_T0.6120.15
457_D465_P0.6120.15
112_G289_R0.6120.15
595_A631_A0.6120.15
535_R578_A0.6110.15
351_D394_S0.6100.15
298_D323_R0.6100.15
146_I523_A0.6100.15
348_E415_G0.6090.15
217_S489_A0.6090.15
427_V432_R0.6080.15
27_D544_L0.6080.15
83_D91_C0.6080.15
438_P449_P0.6080.15
59_A106_F0.6080.15
106_F124_V0.6080.15
305_E662_I0.6070.14
414_R428_P0.6060.14
210_L547_D0.6060.14
134_F507_L0.6050.14
432_R436_V0.6040.14
61_A616_V0.6030.14
243_A353_E0.6030.14
113_A273_C0.6020.14
473_R491_V0.6020.14
126_D614_V0.6020.14
165_D284_D0.6020.14
442_V449_P0.6010.14
35_A294_L0.6010.14
294_L482_A0.6000.14
552_R574_S0.6000.14
419_D431_P0.5980.14
521_V534_M0.5980.14
148_Y175_E0.5980.14
70_R260_D0.5970.14
114_S134_F0.5970.14
36_V573_D0.5970.14
121_S205_R0.5950.14
383_E429_G0.5940.14
148_Y176_R0.5920.14
601_D639_L0.5920.14
121_S171_V0.5920.14
287_T670_R0.5910.14
621_Q656_R0.5910.14
190_V231_L0.5910.14
287_T677_S0.5910.14
356_D584_D0.5910.14
664_D669_E0.5900.14
327_D579_A0.5900.14
488_A491_V0.5890.14
300_R585_L0.5890.14
30_K132_A0.5870.14
162_V562_G0.5870.14
34_L65_L0.5860.14
111_L172_N0.5860.14
30_K645_H0.5860.14
409_P416_D0.5850.14
453_R482_A0.5850.14
140_A571_P0.5850.14
411_D430_Q0.5840.14
398_Q423_A0.5830.14
553_D572_T0.5830.14
119_V241_D0.5820.14
372_D440_T0.5810.14
37_A119_V0.5810.14
509_Q595_A0.5810.14
361_D410_T0.5800.14
354_T407_D0.5790.14
209_A234_F0.5780.14
422_D440_T0.5780.14
460_R464_T0.5780.14
381_G406_G0.5780.14
208_F318_H0.5780.14
167_A203_Q0.5770.14
502_V668_G0.5760.14
235_D421_E0.5750.14
146_I233_G0.5750.14
451_A457_D0.5750.14
137_G591_T0.5740.14
153_N197_E0.5740.14
373_A378_D0.5740.14
138_L145_G0.5740.14
233_G469_A0.5710.14
30_K342_D0.5710.14
177_D677_S0.5700.14
650_D657_G0.5700.14
140_A183_H0.5700.14
67_P585_L0.5690.14
113_A159_L0.5680.14
422_D425_P0.5670.14
350_G476_T0.5670.14
110_P164_L0.5660.14
241_D352_A0.5660.14
377_G381_G0.5660.14
412_G447_D0.5660.14
161_D168_A0.5650.14
273_C284_D0.5650.14
661_D669_E0.5650.14
432_R435_T0.5650.14
240_A344_D0.5640.13
171_V294_L0.5640.13
427_V445_D0.5640.13
233_G422_D0.5630.13
247_D348_E0.5630.13
445_D449_P0.5620.13
267_R334_V0.5620.13
158_H214_V0.5620.13
613_V616_V0.5610.13
350_G485_V0.5600.13
254_D434_D0.5600.13
418_E664_D0.5600.13
388_G401_A0.5590.13
395_E418_E0.5590.13
386_T394_S0.5590.13
294_L298_D0.5580.13
268_E338_H0.5580.13
472_A477_E0.5570.13
267_R557_V0.5570.13
426_L558_V0.5570.13
38_A61_A0.5560.13
388_G417_D0.5560.13
437_E441_G0.5560.13
173_R338_H0.5550.13
426_L432_R0.5550.13
158_H161_D0.5540.13
393_Q412_G0.5540.13
590_R597_L0.5530.13
402_D414_R0.5510.13
415_G434_D0.5510.13
118_V482_A0.5510.13
243_A352_A0.5510.13
420_T443_A0.5510.13
123_S561_A0.5500.13
481_P484_D0.5500.13
415_G418_E0.5500.13
132_A509_Q0.5500.13
31_T294_L0.5500.13
102_R106_F0.5480.13
73_A244_A0.5480.13
433_G447_D0.5470.13
672_P676_L0.5450.13
146_I249_L0.5450.13
440_T445_D0.5440.13
506_D565_A0.5440.13
349_E402_D0.5430.13
336_D444_P0.5430.13
388_G406_G0.5430.13
157_D284_D0.5410.13
379_T445_D0.5410.13
411_D418_E0.5410.13
357_E378_D0.5410.13
348_E427_V0.5400.13
269_I278_V0.5390.13
473_R602_D0.5390.13
134_F172_N0.5390.13
415_G422_D0.5380.13
526_A560_F0.5380.13
75_C144_R0.5370.13
151_E192_T0.5370.13
247_D384_A0.5370.13
356_D377_G0.5370.13
389_P395_E0.5360.13
156_D276_A0.5350.13
57_T168_A0.5350.13
24_V615_V0.5350.13
241_D446_A0.5340.13
249_L576_A0.5340.13
132_A173_R0.5340.13
314_F519_L0.5340.13
344_D413_E0.5330.13
470_R488_A0.5330.13
50_E214_V0.5330.13
294_L492_R0.5330.13
669_E680_R0.5320.13
416_D421_E0.5320.13
432_R447_D0.5300.13
544_L574_S0.5300.13
145_G161_D0.5290.13
380_G396_G0.5290.13
134_F222_D0.5290.13
184_P339_F0.5280.13
29_L222_D0.5260.13
378_D424_A0.5250.13
51_K57_T0.5250.13
222_D407_D0.5250.13
359_G409_P0.5240.13
556_A560_F0.5230.13
98_P422_D0.5220.13
521_V557_V0.5220.13
241_D675_A0.5210.13
97_P101_S0.5200.13
50_E210_L0.5200.13
478_R482_A0.5200.13
401_A428_P0.5190.13
30_K217_S0.5190.13
526_A574_S0.5190.13
295_A319_R0.5190.13
152_V167_A0.5180.12
123_S533_P0.5170.12
248_R270_A0.5160.12
51_K214_V0.5160.12
112_G514_G0.5160.12
82_E91_C0.5150.12
148_Y153_N0.5150.12
225_E228_D0.5140.12
374_E415_G0.5140.12
241_D584_D0.5140.12
439_G451_A0.5140.12
153_N195_P0.5140.12
386_T416_D0.5130.12
357_E429_G0.5120.12
110_P180_S0.5110.12
486_D623_N0.5110.12
290_A558_V0.5110.12
412_G418_E0.5090.12
354_T361_D0.5090.12
549_Y574_S0.5090.12
424_A431_P0.5080.12
79_C172_N0.5080.12
545_L549_Y0.5070.12
145_G157_D0.5070.12
78_G583_K0.5060.12
148_Y203_Q0.5060.12
429_G640_A0.5060.12
500_D681_V0.5050.12
47_V162_V0.5050.12
407_D419_D0.5050.12
32_G483_D0.5040.12
403_S418_E0.5040.12
26_Q29_L0.5040.12
58_T171_V0.5040.12
355_S390_D0.5030.12
274_R322_S0.5030.12
228_D263_E0.5020.12
61_A394_S0.5020.12
29_L42_L0.5020.12
390_D396_G0.5010.12
51_K155_L0.5000.12
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1g8pA 1 0.4551 100 0.808 Contact Map
4ww4B 2 0.4377 100 0.837 Contact Map
4r7yA 3 0.4116 100 0.843 Contact Map
3ja83 1 0.4029 100 0.848 Contact Map
3ja82 1 0.4333 100 0.851 Contact Map
3f8tA 1 0.3667 100 0.855 Contact Map
2r44A 1 0.4377 100 0.857 Contact Map
3ja87 1 0.4116 100 0.858 Contact Map
3ja84 1 0.4145 100 0.866 Contact Map
3ja86 1 0.4029 100 0.868 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0165 seconds.