CBIA - HALSA - GREMLIN Contacts

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CBIA - Cobyrinate a,c-diamide synthase

UniProt:	Q9HPL7	Sequences: MTESESASGMDGVVLGGTASGVGKTVATLAVARALADAGHDVQPAKAGPDFIDPSHHEPVVGTPSRSLDPWLSGTDGMRRTYHQGDGDVCVVEGMMGLYDGSVASTARVASELDLPVVLVVDASAGMQSVAATALGFQAYAAEASVDVDVAGVLAQRAHGGRHADGIRDALPDSLTYFGRVPPRDDLDVPDRHLGLHMGSEAAIDDDAVDAAAAHVAAKRIADVARTPPRPPAHDPAPDTGQTVAVADDAAFCFAYPATRERLRERADVVTFSPVAGDDLPACDGVYLPGGYPELHTDALADAPALDTLGARAADGLPVLGECGGLMALAESLTTTDGDTAEMAGVLPADVRMQDRYQALDHVELRATGDTLTAGSGATLRGHEFHYSAATVASDARFAFAVERGDGIDGDHDGLTEYRTLGTYAHVHPESTAFDAFLDAL	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	441 (420)
Sequences:	2249 (1673)
Seq/√Len:	81.6

HALSA - CBIA
SULSO - CBIA

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
14_V	106_T	4.703	1.00
313_A	319_V	4.271	1.00
135_L	139_A	4.182	1.00
245_A	283_C	4.157	1.00
129_S	137_F	4.136	1.00
243_T	268_D	3.895	1.00
312_R	317_L	3.686	1.00
37_D	210_D	3.572	1.00
92_V	115_L	3.331	1.00
388_S	424_Y	3.228	1.00
182_P	215_H	3.053	1.00
255_A	289_P	3.020	1.00
122_D	157_R	3.019	1.00
286_V	309_L	2.973	1.00
38_A	213_A	2.943	1.00
332_S	350_D	2.780	1.00
250_A	276_A	2.739	1.00
82_Y	113_L	2.685	1.00
164_A	168_R	2.647	1.00
313_A	420_T	2.589	1.00
111_S	141_A	2.587	1.00
212_A	216_V	2.585	1.00
17_G	22_V	2.552	1.00
44_P	61_V	2.546	1.00
28_T	32_A	2.507	1.00
12_G	115_L	2.491	1.00
331_E	348_P	2.474	1.00
260_R	269_V	2.417	1.00
38_A	219_K	2.373	1.00
141_A	147_D	2.358	1.00
332_S	340_T	2.325	1.00
111_S	147_D	2.216	1.00
30_A	212_A	2.216	1.00
37_D	213_A	2.194	1.00
32_A	61_V	2.182	1.00
298_D	302_D	2.143	1.00
246_V	271_T	2.138	1.00
178_F	224_V	2.106	1.00
375_G	378_A	2.069	1.00
121_V	134_A	2.066	1.00
164_A	180_R	2.063	1.00
331_E	350_D	2.057	1.00
280_L	308_T	2.018	1.00
313_A	346_V	1.973	1.00
155_A	171_L	1.964	1.00
118_V	221_I	1.931	1.00
279_D	308_T	1.923	1.00
364_E	379_T	1.915	1.00
244_V	267_A	1.901	1.00
47_A	109_V	1.898	1.00
309_L	344_A	1.897	1.00
32_A	44_P	1.895	1.00
37_D	206_D	1.878	1.00
370_D	375_G	1.878	1.00
243_T	270_V	1.807	1.00
27_A	181_V	1.783	1.00
248_D	271_T	1.775	1.00
57_H	65_S	1.773	1.00
15_L	120_V	1.771	1.00
176_T	220_R	1.769	1.00
134_A	175_L	1.768	1.00
74_G	77_G	1.747	1.00
364_E	381_R	1.743	1.00
247_A	272_F	1.743	1.00
134_A	171_L	1.737	1.00
307_D	311_A	1.710	1.00
84_Q	265_E	1.676	1.00
43_Q	63_T	1.675	1.00
33_R	206_D	1.662	1.00
32_A	57_H	1.657	1.00
33_R	37_D	1.655	1.00
257_P	264_R	1.649	1.00
71_W	381_R	1.646	1.00
35_L	89_V	1.640	1.00
131_A	170_A	1.638	1.00
334_T	340_T	1.638	1.00
370_D	376_S	1.631	1.00
37_D	209_V	1.625	1.00
264_R	271_T	1.613	1.00
365_L	425_A	1.613	1.00
155_A	177_Y	1.611	1.00
367_A	374_A	1.608	1.00
327_M	351_V	1.601	1.00
296_H	299_A	1.600	1.00
286_V	317_L	1.599	1.00
301_A	342_E	1.596	1.00
257_P	261_E	1.590	1.00
330_A	349_A	1.589	1.00
280_L	283_C	1.589	1.00
126_G	133_T	1.583	1.00
330_A	351_V	1.577	1.00
347_L	420_T	1.577	1.00
366_R	379_T	1.564	1.00
18_T	22_V	1.563	1.00
310_G	314_A	1.559	1.00
14_V	115_L	1.550	1.00
305_A	308_T	1.530	0.99
161_G	182_P	1.524	0.99
34_A	218_A	1.523	0.99
118_V	154_L	1.518	0.99
261_E	264_R	1.513	0.99
314_A	418_Y	1.500	0.99
209_V	213_A	1.494	0.99
246_V	269_V	1.492	0.99
277_G	306_L	1.487	0.99
27_A	154_L	1.480	0.99
114_D	149_D	1.467	0.99
198_M	253_C	1.460	0.99
75_T	108_R	1.445	0.99
366_R	401_A	1.440	0.99
353_M	424_Y	1.438	0.99
220_R	223_D	1.438	0.99
303_A	306_L	1.437	0.99
89_V	222_A	1.434	0.99
47_A	95_M	1.434	0.99
297_T	341_A	1.420	0.99
13_V	91_V	1.405	0.99
216_V	221_I	1.403	0.99
40_H	88_D	1.399	0.99
353_M	388_S	1.397	0.99
319_V	420_T	1.389	0.99
13_V	225_A	1.388	0.99
118_V	178_F	1.383	0.99
32_A	91_V	1.357	0.99
12_G	228_P	1.344	0.99
246_V	260_R	1.341	0.99
124_S	157_R	1.341	0.99
66_R	261_E	1.311	0.98
244_V	285_G	1.299	0.98
303_A	328_A	1.285	0.98
327_M	388_S	1.285	0.98
32_A	65_S	1.282	0.98
354_Q	389_A	1.280	0.98
308_T	312_R	1.268	0.98
123_A	167_I	1.267	0.98
184_R	211_A	1.265	0.98
340_T	350_D	1.264	0.98
40_H	222_A	1.256	0.98
245_A	286_V	1.250	0.98
247_A	274_P	1.249	0.98
41_D	88_D	1.241	0.98
27_A	120_V	1.234	0.98
117_V	148_V	1.226	0.97
297_T	333_L	1.225	0.97
288_L	309_L	1.223	0.97
70_P	112_E	1.220	0.97
121_V	130_V	1.219	0.97
13_V	118_V	1.215	0.97
70_P	109_V	1.209	0.97
141_A	148_V	1.205	0.97
16_G	117_V	1.205	0.97
95_M	106_T	1.201	0.97
33_R	209_V	1.199	0.97
82_Y	115_L	1.197	0.97
135_L	140_Y	1.188	0.97
185_D	188_D	1.182	0.97
327_M	333_L	1.178	0.97
264_R	268_D	1.169	0.97
180_R	215_H	1.165	0.97
198_M	292_Y	1.163	0.97
138_Q	150_V	1.149	0.96
335_T	339_D	1.148	0.96
12_G	82_Y	1.144	0.96
243_T	283_C	1.139	0.96
306_L	309_L	1.138	0.96
210_D	214_A	1.137	0.96
58_E	66_R	1.133	0.96
334_T	350_D	1.132	0.96
98_L	148_V	1.132	0.96
225_A	228_P	1.130	0.96
300_L	328_A	1.129	0.96
249_D	273_S	1.129	0.96
335_T	341_A	1.125	0.96
334_T	352_R	1.110	0.95
329_L	420_T	1.099	0.95
89_V	225_A	1.099	0.95
321_G	422_G	1.097	0.95
365_L	402_V	1.095	0.95
161_G	165_D	1.093	0.95
159_H	183_P	1.086	0.95
12_G	114_D	1.086	0.95
103_V	108_R	1.084	0.95
35_L	222_A	1.084	0.95
242_Q	267_A	1.083	0.95
270_V	283_C	1.081	0.95
80_R	84_Q	1.081	0.95
44_P	65_S	1.075	0.95
306_L	328_A	1.074	0.95
292_Y	295_L	1.070	0.94
77_G	81_T	1.067	0.94
41_D	86_D	1.058	0.94
151_A	224_V	1.048	0.94
280_L	306_L	1.048	0.94
142_A	147_D	1.043	0.94
79_R	112_E	1.036	0.93
123_A	158_A	1.036	0.93
78_M	109_V	1.033	0.93
111_S	148_V	1.033	0.93
277_G	303_A	1.031	0.93
41_D	63_T	1.031	0.93
63_T	87_G	1.027	0.93
128_Q	140_Y	1.022	0.93
178_F	220_R	1.015	0.93
186_D	207_D	1.013	0.93
352_R	389_A	1.009	0.92
11_D	228_P	1.009	0.92
349_A	390_A	1.008	0.92
119_L	129_S	0.998	0.92
259_T	429_P	0.997	0.92
319_V	346_V	0.991	0.92
211_A	215_H	0.989	0.92
400_F	421_L	0.980	0.91
187_L	211_A	0.978	0.91
350_D	391_T	0.975	0.91
10_M	90_C	0.972	0.91
330_A	390_A	0.971	0.91
286_V	319_V	0.971	0.91
374_A	378_A	0.969	0.91
15_L	118_V	0.966	0.91
287_Y	320_L	0.963	0.91
165_D	169_D	0.960	0.91
126_G	130_V	0.958	0.90
75_T	112_E	0.957	0.90
123_A	155_A	0.956	0.90
181_V	211_A	0.953	0.90
107_A	148_V	0.952	0.90
104_A	109_V	0.946	0.90
404_R	408_I	0.939	0.90
178_F	221_I	0.938	0.89
258_A	261_E	0.937	0.89
368_T	401_A	0.937	0.89
102_S	128_Q	0.934	0.89
158_A	167_I	0.932	0.89
371_T	374_A	0.924	0.89
18_T	137_F	0.918	0.88
55_S	198_M	0.916	0.88
34_A	38_A	0.915	0.88
277_G	328_A	0.910	0.88
35_L	40_H	0.909	0.88
312_R	319_V	0.909	0.88
330_A	347_L	0.908	0.88
331_E	349_A	0.906	0.88
17_G	137_F	0.906	0.88
19_A	22_V	0.903	0.88
43_Q	87_G	0.901	0.88
56_H	205_D	0.898	0.87
19_A	122_D	0.892	0.87
133_T	137_F	0.892	0.87
70_P	78_M	0.889	0.87
12_G	92_V	0.887	0.87
45_A	90_C	0.887	0.87
363_V	404_R	0.885	0.87
43_Q	58_E	0.885	0.87
327_M	343_M	0.885	0.87
241_G	268_D	0.884	0.86
78_M	112_E	0.880	0.86
285_G	318_P	0.880	0.86
106_T	115_L	0.875	0.86
278_D	303_A	0.875	0.86
27_A	212_A	0.874	0.86
33_R	60_V	0.871	0.86
286_V	312_R	0.870	0.86
206_D	209_V	0.865	0.85
58_E	64_P	0.863	0.85
63_T	86_D	0.862	0.85
191_D	387_Y	0.861	0.85
110_A	117_V	0.859	0.85
217_A	220_R	0.857	0.85
98_L	117_V	0.855	0.85
142_A	148_V	0.852	0.84
38_A	222_A	0.851	0.84
31_V	212_A	0.848	0.84
162_R	165_D	0.842	0.84
96_M	127_M	0.841	0.84
184_R	187_L	0.840	0.84
155_A	180_R	0.840	0.84
26_V	57_H	0.839	0.83
259_T	263_L	0.837	0.83
301_A	341_A	0.836	0.83
304_P	307_D	0.834	0.83
311_A	315_D	0.832	0.83
320_L	421_L	0.830	0.83
243_T	284_D	0.830	0.83
307_D	310_G	0.825	0.82
312_R	315_D	0.825	0.82
352_R	391_T	0.817	0.82
210_D	213_A	0.815	0.82
157_R	183_P	0.810	0.81
331_E	345_G	0.807	0.81
102_S	111_S	0.804	0.81
59_P	205_D	0.800	0.80
98_L	141_A	0.798	0.80
119_L	137_F	0.796	0.80
114_D	229_P	0.795	0.80
335_T	338_G	0.793	0.80
168_R	172_P	0.792	0.80
70_P	108_R	0.791	0.80
57_H	61_V	0.786	0.79
378_A	434_F	0.783	0.79
171_L	177_Y	0.781	0.79
71_W	272_F	0.781	0.79
313_A	344_A	0.781	0.79
99_Y	148_V	0.780	0.79
92_V	113_L	0.777	0.79
224_V	228_P	0.777	0.79
278_D	306_L	0.776	0.78
278_D	305_A	0.776	0.78
135_L	138_Q	0.773	0.78
52_I	193_H	0.773	0.78
76_D	298_D	0.772	0.78
242_Q	245_A	0.771	0.78
228_P	231_P	0.768	0.78
298_D	339_D	0.764	0.77
55_S	199_G	0.760	0.77
413_D	425_A	0.760	0.77
346_V	420_T	0.757	0.77
280_L	303_A	0.755	0.77
47_A	106_T	0.755	0.77
176_T	179_G	0.754	0.76
330_A	333_L	0.752	0.76
310_G	344_A	0.748	0.76
198_M	201_E	0.746	0.76
131_A	140_Y	0.744	0.75
259_T	287_Y	0.744	0.75
108_R	112_E	0.744	0.75
96_M	100_D	0.742	0.75
52_I	56_H	0.741	0.75
359_A	389_A	0.738	0.75
40_H	89_V	0.737	0.75
250_A	299_A	0.732	0.74
367_A	378_A	0.732	0.74
239_D	242_Q	0.732	0.74
94_G	106_T	0.732	0.74
96_M	191_D	0.731	0.74
198_M	295_L	0.729	0.74
283_C	317_L	0.728	0.74
73_S	81_T	0.728	0.74
299_A	310_G	0.727	0.74
430_E	433_A	0.727	0.74
11_D	225_A	0.726	0.74
81_T	109_V	0.724	0.73
51_F	253_C	0.724	0.73
31_V	35_L	0.724	0.73
231_P	235_D	0.723	0.73
207_D	210_D	0.722	0.73
18_T	129_S	0.721	0.73
334_T	338_G	0.721	0.73
368_T	412_H	0.721	0.73
168_R	217_A	0.719	0.73
280_L	312_R	0.719	0.73
115_L	228_P	0.716	0.73
200_S	248_D	0.714	0.72
19_A	126_G	0.713	0.72
164_A	182_P	0.713	0.72
211_A	214_A	0.713	0.72
309_L	328_A	0.708	0.72
35_L	91_V	0.706	0.72
367_A	371_T	0.705	0.71
33_R	36_A	0.704	0.71
73_S	78_M	0.701	0.71
36_A	60_V	0.700	0.71
12_G	229_P	0.699	0.71
71_W	104_A	0.698	0.71
11_D	227_T	0.698	0.71
323_C	426_H	0.698	0.71
98_L	107_A	0.695	0.70
123_A	177_Y	0.695	0.70
32_A	42_V	0.692	0.70
100_D	361_D	0.692	0.70
219_K	222_A	0.690	0.70
129_S	133_T	0.689	0.70
13_V	221_I	0.687	0.70
297_T	301_A	0.687	0.70
360_L	411_D	0.687	0.70
121_V	137_F	0.684	0.69
16_G	95_M	0.684	0.69
194_L	383_H	0.681	0.69
367_A	370_D	0.680	0.69
15_L	221_I	0.679	0.69
25_T	196_L	0.679	0.69
360_L	363_V	0.675	0.68
311_A	314_A	0.674	0.68
354_Q	358_Q	0.674	0.68
127_M	166_G	0.672	0.68
255_A	269_V	0.671	0.68
402_V	425_A	0.668	0.67
253_C	292_Y	0.667	0.67
82_Y	90_C	0.667	0.67
160_G	183_P	0.666	0.67
66_R	258_A	0.666	0.67
366_R	403_E	0.665	0.67
14_V	92_V	0.665	0.67
208_A	213_A	0.663	0.67
332_S	342_E	0.662	0.67
243_T	271_T	0.661	0.67
155_A	167_I	0.660	0.66
71_W	364_E	0.658	0.66
404_R	409_D	0.656	0.66
247_A	273_S	0.655	0.66
56_H	202_A	0.653	0.66
415_L	422_G	0.651	0.65
272_F	306_L	0.651	0.65
369_G	397_R	0.650	0.65
405_G	408_I	0.650	0.65
130_V	155_A	0.645	0.65
189_V	208_A	0.642	0.64
283_C	286_V	0.641	0.64
107_A	141_A	0.640	0.64
282_A	337_D	0.638	0.64
220_R	224_V	0.638	0.64
58_E	61_V	0.637	0.64
160_G	163_H	0.636	0.64
72_L	259_T	0.636	0.64
326_L	390_A	0.634	0.63
35_L	218_A	0.634	0.63
15_L	27_A	0.633	0.63
193_H	323_C	0.631	0.63
209_V	216_V	0.628	0.63
314_A	417_E	0.628	0.63
182_P	211_A	0.627	0.62
320_L	427_V	0.627	0.62
334_T	391_T	0.626	0.62
15_L	131_A	0.626	0.62
326_L	422_G	0.626	0.62
34_A	213_A	0.625	0.62
34_A	209_V	0.624	0.62
326_L	423_T	0.624	0.62
279_D	306_L	0.623	0.62
159_H	163_H	0.622	0.62
74_G	78_M	0.621	0.62
51_F	327_M	0.620	0.62
76_D	79_R	0.619	0.62
55_S	253_C	0.619	0.62
313_A	347_L	0.619	0.62
36_A	61_V	0.618	0.61
224_V	227_T	0.616	0.61
295_L	387_Y	0.616	0.61
404_R	411_D	0.613	0.61
172_P	216_V	0.611	0.61
150_V	175_L	0.611	0.61
189_V	202_A	0.611	0.61
64_P	257_P	0.610	0.60
194_L	323_C	0.610	0.60
152_G	178_F	0.608	0.60
102_S	141_A	0.607	0.60
76_D	223_D	0.607	0.60
367_A	377_G	0.607	0.60
75_T	79_R	0.605	0.60
164_A	177_Y	0.605	0.60
363_V	384_E	0.605	0.60
167_I	171_L	0.604	0.60
391_T	395_D	0.603	0.60
44_P	424_Y	0.601	0.59
72_L	382_G	0.600	0.59
382_G	425_A	0.598	0.59
373_T	377_G	0.597	0.59
50_D	53_D	0.597	0.59
370_D	373_T	0.597	0.59
212_A	215_H	0.596	0.59
402_V	405_G	0.596	0.59
400_F	404_R	0.594	0.58
394_S	417_E	0.594	0.58
333_L	343_M	0.594	0.58
364_E	403_E	0.593	0.58
159_H	359_A	0.592	0.58
429_P	432_T	0.592	0.58
111_S	149_D	0.591	0.58
358_Q	389_A	0.589	0.58
327_M	330_A	0.588	0.58
192_R	254_F	0.587	0.57
67_S	362_H	0.586	0.57
238_P	299_A	0.586	0.57
11_D	226_R	0.585	0.57
70_P	74_G	0.585	0.57
208_A	216_V	0.585	0.57
298_D	341_A	0.585	0.57
367_A	416_T	0.584	0.57
26_V	353_M	0.583	0.57
270_V	285_G	0.582	0.57
316_G	419_R	0.582	0.57
30_A	209_V	0.581	0.57
61_V	65_S	0.580	0.57
96_M	166_G	0.580	0.57
168_R	177_Y	0.578	0.56
279_D	282_A	0.578	0.56
70_P	104_A	0.577	0.56
310_G	319_V	0.575	0.56
72_L	428_H	0.574	0.56
130_V	167_I	0.574	0.56
275_V	361_D	0.573	0.56
159_H	360_L	0.573	0.56
276_A	306_L	0.573	0.56
36_A	89_V	0.571	0.55
153_V	171_L	0.570	0.55
273_S	306_L	0.570	0.55
313_A	316_G	0.569	0.55
416_T	419_R	0.568	0.55
99_Y	162_R	0.567	0.55
30_A	34_A	0.567	0.55
288_L	324_G	0.567	0.55
31_V	218_A	0.567	0.55
277_G	305_A	0.566	0.55
29_L	60_V	0.566	0.55
66_R	428_H	0.565	0.55
30_A	181_V	0.564	0.54
14_V	109_V	0.563	0.54
398_F	408_I	0.562	0.54
189_V	197_H	0.562	0.54
184_R	207_D	0.561	0.54
96_M	361_D	0.560	0.54
401_A	412_H	0.559	0.54
261_E	265_E	0.559	0.54
150_V	154_L	0.559	0.54
245_A	270_V	0.559	0.54
96_M	194_L	0.558	0.54
255_A	287_Y	0.558	0.54
20_S	96_M	0.557	0.54
355_D	389_A	0.557	0.54
277_G	308_T	0.555	0.53
31_V	221_I	0.555	0.53
347_L	415_L	0.555	0.53
260_R	271_T	0.554	0.53
245_A	288_L	0.553	0.53
178_F	218_A	0.552	0.53
324_G	327_M	0.552	0.53
49_P	100_D	0.551	0.53
254_F	323_C	0.551	0.53
155_A	164_A	0.551	0.53
404_R	407_G	0.551	0.53
160_G	360_L	0.548	0.52
177_Y	180_R	0.547	0.52
66_R	85_G	0.547	0.52
279_D	305_A	0.546	0.52
124_S	183_P	0.545	0.52
33_R	212_A	0.544	0.52
79_R	378_A	0.544	0.52
128_Q	289_P	0.543	0.52
68_L	78_M	0.543	0.52
254_F	385_F	0.543	0.52
402_V	413_D	0.542	0.52
37_D	214_A	0.541	0.51
191_D	327_M	0.539	0.51
192_R	293_P	0.539	0.51
275_V	299_A	0.538	0.51
194_L	385_F	0.538	0.51
20_S	95_M	0.537	0.51
20_S	24_K	0.537	0.51
276_A	299_A	0.537	0.51
233_A	369_G	0.537	0.51
73_S	77_G	0.537	0.51
163_H	360_L	0.537	0.51
151_A	178_F	0.537	0.51
36_A	63_T	0.536	0.51
16_G	98_L	0.536	0.51
43_Q	66_R	0.535	0.51
31_V	91_V	0.533	0.50
158_A	164_A	0.533	0.50
13_V	89_V	0.532	0.50
98_L	110_A	0.532	0.50
399_A	404_R	0.531	0.50
95_M	357_Y	0.531	0.50
108_R	111_S	0.530	0.50
222_A	226_R	0.529	0.50
12_G	225_A	0.529	0.50
40_H	219_K	0.529	0.50
351_V	390_A	0.529	0.50
109_V	112_E	0.528	0.50
172_P	177_Y	0.528	0.50
254_F	383_H	0.527	0.50
121_V	129_S	0.527	0.50
326_L	387_Y	0.527	0.50
208_A	212_A	0.525	0.49
398_F	413_D	0.524	0.49
274_P	288_L	0.523	0.49
288_L	317_L	0.523	0.49
363_V	402_V	0.522	0.49
326_L	394_S	0.522	0.49
12_G	227_T	0.522	0.49
197_H	201_E	0.521	0.49
220_R	235_D	0.520	0.49
229_P	232_P	0.520	0.49
193_H	385_F	0.519	0.49
320_L	414_G	0.519	0.49
42_V	88_D	0.519	0.49
198_M	202_A	0.518	0.48
12_G	90_C	0.518	0.48
370_D	377_G	0.518	0.48
51_F	319_V	0.517	0.48
77_G	428_H	0.516	0.48
245_A	272_F	0.516	0.48
405_G	413_D	0.516	0.48
110_A	148_V	0.515	0.48
193_H	254_F	0.515	0.48
242_Q	268_D	0.515	0.48
159_H	164_A	0.515	0.48
326_L	413_D	0.515	0.48
125_A	374_A	0.514	0.48
104_A	129_S	0.514	0.48
252_F	277_G	0.513	0.48
358_Q	363_V	0.513	0.48
357_Y	360_L	0.512	0.48
22_V	26_V	0.512	0.48
313_A	418_Y	0.511	0.48
363_V	425_A	0.511	0.48
33_R	63_T	0.510	0.47
195_G	254_F	0.510	0.47
231_P	236_P	0.510	0.47
28_T	57_H	0.509	0.47
48_G	53_D	0.509	0.47
31_V	216_V	0.509	0.47
287_Y	347_L	0.507	0.47
20_S	360_L	0.507	0.47
51_F	383_H	0.507	0.47
183_P	360_L	0.507	0.47
29_L	56_H	0.506	0.47
193_H	295_L	0.506	0.47
96_M	357_Y	0.504	0.47
323_C	385_F	0.504	0.47
151_A	176_T	0.504	0.47
230_R	307_D	0.503	0.47
29_L	65_S	0.502	0.46
181_V	208_A	0.502	0.46
153_V	179_G	0.502	0.46
190_P	209_V	0.502	0.46
99_Y	104_A	0.501	0.46
42_V	89_V	0.501	0.46
309_L	346_V	0.501	0.46
323_C	383_H	0.501	0.46
238_P	241_G	0.500	0.46
126_G	137_F	0.500	0.46

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1s1mA	4	0.9342	100	0.678	Contact Map
1vcoA	4	0.9093	100	0.698	Contact Map
3nvaA	2	0.9342	100	0.706	Contact Map
4zdjA	4	0.9138	100	0.708	Contact Map
4a0gA	2	0.6825	100	0.828	Contact Map
3fijA	4	0.4263	99.9	0.859	Contact Map
1ka9H	1	0.424	99.9	0.862	Contact Map
3fgnA	2	0.4535	99.9	0.863	Contact Map
3ug7A	4	0.4399	99.9	0.865	Contact Map
2issD	1	0.4082	99.9	0.865	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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