GREMLIN Database
Q9HPI5 - Uncharacterized protein
UniProt: Q9HPI5 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 151 (135)
Sequences: 1251 (1062)
Seq/√Len: 91.4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
27_S38_S3.7471.00
95_L134_F3.5881.00
96_Q135_R2.8181.00
28_F67_P2.7771.00
96_Q137_H2.6641.00
21_G43_Y2.6571.00
25_V77_V2.5581.00
74_V136_L2.5141.00
25_V79_H2.4601.00
25_V38_S2.4571.00
51_S135_R2.3781.00
41_V54_F2.3531.00
18_L78_V2.3121.00
28_F74_V2.2431.00
56_L65_P2.1561.00
24_G76_F2.0891.00
97_P132_L2.0261.00
95_L136_L2.0151.00
16_A20_P1.8731.00
23_T79_H1.7331.00
63_D92_H1.6841.00
74_V95_L1.6791.00
29_G71_P1.6701.00
65_P134_F1.6571.00
47_P50_E1.6371.00
13_D145_A1.6291.00
80_D87_C1.5901.00
39_L90_V1.5631.00
43_Y78_V1.5221.00
46_D110_A1.4951.00
103_I135_R1.4631.00
44_G114_V1.4420.99
91_A141_I1.4160.99
11_P15_D1.3960.99
92_H140_A1.3850.99
108_L131_F1.3760.99
54_F134_F1.3680.99
52_F76_F1.3120.99
21_G78_V1.3010.99
105_T109_S1.2880.99
75_S90_V1.2770.99
46_D106_T1.2560.99
44_G107_A1.2390.98
94_R139_D1.1700.98
52_F91_A1.1680.98
43_Y76_F1.1650.98
75_S92_H1.1580.97
22_G82_A1.1470.97
14_R89_V1.1450.97
120_D124_R1.1330.97
65_P69_T1.1240.97
72_L94_R1.1140.97
68_E95_L1.0870.96
52_F138_P1.0840.96
24_G91_A1.0660.96
65_P132_L1.0550.96
6_A9_L1.0540.96
10_E13_D1.0530.96
30_R63_D1.0530.96
51_S137_H1.0480.95
27_S90_V1.0360.95
33_A73_D1.0310.95
97_P134_F1.0260.95
119_L122_F1.0230.95
13_D87_C1.0040.94
38_S77_V1.0000.94
33_A67_P1.0000.94
66_D69_T0.9880.94
93_G136_L0.9810.94
9_L17_F0.9780.93
138_P141_I0.9720.93
46_D50_E0.9630.93
15_D45_Y0.9620.93
42_S82_A0.9610.93
29_G33_A0.9530.93
29_G67_P0.9490.92
43_Y115_D0.9280.92
123_D128_E0.9280.92
73_D94_R0.9250.91
40_P90_V0.9220.91
69_T132_L0.9210.91
40_P77_V0.9150.91
67_P92_H0.9150.91
125_P128_E0.9140.91
9_L145_A0.9130.91
8_H11_P0.9090.91
44_G110_A0.9070.91
125_P129_T0.8730.89
63_D67_P0.8620.88
26_L41_V0.8360.87
112_R116_I0.8280.86
59_G130_E0.8170.85
69_T97_P0.8120.85
14_R143_A0.7940.84
108_L133_F0.7930.84
100_A103_I0.7900.83
76_F91_A0.7900.83
124_R129_T0.7900.83
54_F136_L0.7870.83
85_G146_D0.7860.83
55_R144_R0.7760.82
7_V146_D0.7690.82
28_F136_L0.7670.82
122_F126_L0.7670.82
15_D19_A0.7640.81
106_T110_A0.7580.81
17_F87_C0.7580.81
16_A19_A0.7550.81
79_H82_A0.7520.80
87_C145_A0.7500.80
68_E97_P0.7460.80
7_V10_E0.7390.79
19_A45_Y0.7380.79
30_R67_P0.7370.79
37_H63_D0.7360.79
109_S113_R0.7330.79
104_S108_L0.7230.78
110_A113_R0.7130.77
104_S133_F0.7100.76
91_A138_P0.7100.76
36_P93_G0.7070.76
119_L123_D0.7020.76
86_W146_D0.7010.75
113_R120_D0.6960.75
21_G80_D0.6890.74
124_R128_E0.6880.74
38_S79_H0.6800.73
56_L134_F0.6780.73
16_A94_R0.6750.73
52_F143_A0.6730.72
42_S84_H0.6720.72
84_H115_D0.6690.72
42_S115_D0.6670.72
107_A133_F0.6660.72
16_A137_H0.6650.72
68_E134_F0.6620.71
38_S75_S0.6530.70
10_E14_R0.6510.70
121_T124_R0.6480.70
120_D123_D0.6470.69
73_D139_D0.6460.69
91_A136_L0.6460.69
12_D16_A0.6400.69
67_P143_A0.6370.68
13_D16_A0.6280.67
103_I107_A0.6250.67
103_I106_T0.6250.67
31_E70_T0.6170.66
18_L76_F0.6160.66
15_D50_E0.6140.65
24_G114_V0.6110.65
42_S112_R0.6100.65
58_Y130_E0.6090.65
76_F138_P0.6080.65
56_L132_L0.6080.65
51_S138_P0.6050.64
36_P71_P0.6050.64
109_S123_D0.6050.64
123_D126_L0.6000.64
18_L89_V0.5960.63
16_A59_G0.5960.63
42_S57_S0.5930.63
86_W144_R0.5860.62
28_F39_L0.5860.62
69_T137_H0.5830.61
29_G36_P0.5830.61
83_D108_L0.5810.61
12_D31_E0.5740.60
126_L129_T0.5720.60
7_V11_P0.5710.60
107_A111_L0.5640.59
24_G78_V0.5630.59
25_V90_V0.5620.59
15_D47_P0.5610.59
32_D106_T0.5570.58
87_C115_D0.5550.58
44_G84_H0.5510.57
13_D45_Y0.5510.57
88_S142_T0.5500.57
115_D144_R0.5440.56
14_R141_I0.5420.56
102_A106_T0.5390.56
32_D73_D0.5380.55
28_F68_E0.5370.55
78_V138_P0.5330.55
89_V141_I0.5330.55
18_L52_F0.5310.54
23_T82_A0.5280.54
72_L96_Q0.5280.54
23_T38_S0.5270.54
30_R70_T0.5270.54
16_A31_E0.5230.53
7_V14_R0.5230.53
125_P131_F0.5220.53
20_P80_D0.5200.53
17_F80_D0.5160.52
76_F89_V0.5150.52
54_F64_K0.5100.52
58_Y132_L0.5080.51
33_A92_H0.5050.51
109_S124_R0.5030.51
62_T108_L0.5000.50
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2ol5A 2 0.9139 100 0.416 Contact Map
2vpaA 2 0.9669 100 0.428 Contact Map
2furA 2 0.9272 100 0.445 Contact Map
2htiA 2 0.8344 100 0.447 Contact Map
2fg9A 4 0.9536 99.9 0.459 Contact Map
3u5wA 2 0.8146 99.9 0.495 Contact Map
3fkhA 2 0.8742 99.9 0.5 Contact Map
3cp3A 2 0.8278 99.9 0.501 Contact Map
2hq9A 2 0.8675 99.9 0.506 Contact Map
1rfeA 1 0.9669 99.9 0.508 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0063 seconds.