TRPE1 - HALSA - GREMLIN Contacts

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TRPE1 - Anthranilate synthase component 1 1

UniProt:	Q9HPG5	Sequences: MIETDRETFTALADDGPAIVRVAADLDIDVAPLTAYDALVADADDHAFLLESAEKTPASDPDGAFTPDTTTEETRHARYSFVGYDPAAVVTVDPDDTTITRLRDDPITDLLDAPDHATGDVLDRLRSVMPAVPRRNIPTEDRQLLDGGLVGFLAYDAVYDLWLDEVGVERPPTPLPDAEFAVTTRTLVFDRATDSVSLVCTPVADADTATDVYDALEAEAKRVQAVLRDATAPATAGIEVTTERAGDRDAYTDAVETAATAVRDGEVYQAVVSRTRELDGDIDPRALYDALRAVNPSPYMFLLAHGDHTVVGASPETLVAVHDDTVVTNPIAGTCQRGASPVADRRLAGEMLADEKERAEHTMLVDLARNDVRRVSAPGTVSVPEFMRVLKYSHVQHIESTVTGTLAADADAFDATRAAFPAGTLSGAPKVRAMEHIDAIEATPRGIYGGGVGYFSWTGDAELAITIRSGTITHTGDEDTLTVRAGAGVVADSDPDAEYEETEAKMDGVLAAVDRLRTTDDGEAVHR	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	527 (452)
Sequences:	4845 (3174)
Seq/√Len:	149.3

ECOLI - TRPE PABB MENF ENTC
BACSU - TRPE PABB MENF
HALSA - TRPE1 TRPE2 Q9HQN2
SULSO - TRPE

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
126_R	411_D	4.521	1.00
377_A	405_T	4.349	1.00
376_S	404_G	4.229	1.00
425_L	449_G	4.195	1.00
377_A	408_A	3.634	1.00
248_R	252_T	3.359	1.00
335_C	350_E	3.108	1.00
325_T	403_T	3.052	1.00
261_A	266_E	2.957	1.00
494_D	497_A	2.920	1.00
334_T	395_V	2.861	1.00
277_E	480_T	2.835	1.00
248_R	496_D	2.827	1.00
384_P	403_T	2.801	1.00
261_A	439_A	2.776	1.00
65_F	83_G	2.752	1.00
120_D	417_R	2.726	1.00
120_D	123_D	2.646	1.00
251_Y	487_A	2.645	1.00
385_E	388_R	2.592	1.00
252_T	496_D	2.566	1.00
247_D	250_A	2.514	1.00
277_E	482_T	2.445	1.00
453_G	463_L	2.416	1.00
473_T	478_E	2.374	1.00
260_T	264_D	2.358	1.00
155_Y	434_M	2.351	1.00
382_S	403_T	2.323	1.00
348_A	391_K	2.305	1.00
432_R	435_E	2.298	1.00
345_R	349_G	2.275	1.00
349_G	353_A	2.260	1.00
279_D	480_T	2.235	1.00
246_G	254_A	2.207	1.00
324_D	405_T	2.193	1.00
253_D	256_E	2.193	1.00
410_A	414_D	2.184	1.00
407_A	410_A	2.170	1.00
310_V	447_I	2.161	1.00
258_A	270_A	2.143	1.00
78_R	190_D	2.129	1.00
337_R	344_D	2.086	1.00
267_V	270_A	2.069	1.00
325_T	405_T	2.068	1.00
389_V	398_I	2.024	1.00
372_V	376_S	1.996	1.00
352_L	398_I	1.996	1.00
81_F	188_V	1.996	1.00
284_P	309_T	1.982	1.00
65_F	150_V	1.955	1.00
345_R	348_A	1.885	1.00
341_P	345_R	1.863	1.00
496_D	500_E	1.794	1.00
272_V	487_A	1.791	1.00
269_Q	488_G	1.791	1.00
422_A	465_I	1.773	1.00
436_H	440_I	1.771	1.00
245_A	443_T	1.765	1.00
301_F	452_V	1.752	1.00
283_D	286_A	1.741	1.00
311_V	472_I	1.728	1.00
472_I	481_L	1.727	1.00
391_K	396_Q	1.711	1.00
447_I	466_T	1.699	1.00
301_F	312_G	1.695	1.00
339_A	343_A	1.691	1.00
343_A	346_R	1.652	1.00
55_K	289_D	1.647	1.00
328_T	368_A	1.647	1.00
164_D	435_E	1.633	1.00
256_E	259_A	1.633	1.00
331_I	399_E	1.623	1.00
416_T	455_F	1.620	1.00
500_E	504_A	1.614	1.00
375_V	418_A	1.610	1.00
338_G	343_A	1.600	1.00
149_L	182_V	1.597	1.00
248_R	499_Y	1.596	1.00
256_E	495_P	1.587	1.00
260_T	263_R	1.582	1.00
46_H	50_L	1.581	1.00
50_L	54_E	1.564	1.00
346_R	350_E	1.547	1.00
347_L	350_E	1.546	1.00
258_A	272_V	1.540	1.00
326_V	376_S	1.539	1.00
91_T	98_T	1.533	1.00
213_Y	217_E	1.532	1.00
54_E	64_A	1.529	1.00
487_A	502_T	1.504	1.00
304_A	309_T	1.503	1.00
372_V	404_G	1.494	1.00
373_R	379_G	1.489	1.00
171_P	174_P	1.485	1.00
470_G	481_L	1.475	1.00
242_T	278_L	1.472	1.00
121_V	178_A	1.470	1.00
198_L	220_A	1.458	1.00
156_D	438_D	1.457	1.00
329_N	390_L	1.451	1.00
261_A	432_R	1.438	1.00
377_A	407_A	1.428	1.00
390_L	399_E	1.418	1.00
255_V	495_P	1.417	1.00
326_V	372_V	1.412	1.00
168_V	438_D	1.411	1.00
45_D	50_L	1.397	1.00
317_T	462_E	1.393	1.00
63_G	89_V	1.390	1.00
312_G	464_A	1.389	1.00
250_A	442_A	1.377	1.00
257_T	439_A	1.376	1.00
327_V	403_T	1.375	1.00
416_T	463_L	1.374	1.00
261_A	436_H	1.371	1.00
153_L	157_A	1.371	1.00
340_S	343_A	1.361	1.00
301_F	310_V	1.358	1.00
338_G	347_L	1.350	1.00
280_G	472_I	1.347	1.00
354_D	357_E	1.346	1.00
329_N	385_E	1.344	1.00
243_E	279_D	1.339	1.00
348_A	389_V	1.329	1.00
252_T	256_E	1.328	1.00
188_V	199_V	1.324	1.00
497_A	500_E	1.317	1.00
68_D	292_R	1.311	1.00
322_H	460_D	1.309	1.00
156_D	444_P	1.303	1.00
185_R	219_E	1.301	1.00
454_Y	462_E	1.283	1.00
287_L	472_I	1.273	1.00
248_R	500_E	1.269	1.00
432_R	439_A	1.267	1.00
252_T	495_P	1.265	1.00
499_Y	503_E	1.261	1.00
121_V	160_D	1.261	1.00
274_R	502_T	1.260	1.00
413_F	455_F	1.259	1.00
255_V	489_V	1.258	1.00
302_L	309_T	1.255	1.00
272_V	489_V	1.254	1.00
321_V	326_V	1.253	1.00
384_P	401_T	1.248	1.00
362_T	386_F	1.243	1.00
406_L	415_A	1.226	1.00
80_S	191_R	1.224	1.00
342_V	346_R	1.222	1.00
271_V	486_G	1.221	1.00
321_V	415_A	1.212	1.00
46_H	49_L	1.211	1.00
153_L	455_F	1.206	1.00
365_V	386_F	1.206	1.00
250_A	253_D	1.206	1.00
500_E	503_E	1.203	1.00
362_T	387_M	1.191	1.00
287_L	470_G	1.189	1.00
137_I	141_D	1.182	1.00
447_I	471_T	1.181	1.00
210_T	214_D	1.174	1.00
89_V	179_E	1.168	1.00
253_D	257_T	1.168	1.00
249_D	253_D	1.167	1.00
54_E	57_P	1.166	1.00
284_P	472_I	1.164	1.00
126_R	130_P	1.158	1.00
189_F	196_V	1.156	1.00
257_T	260_T	1.153	1.00
165_E	435_E	1.153	1.00
372_V	419_A	1.153	1.00
126_R	414_D	1.148	1.00
470_G	509_V	1.147	1.00
182_V	457_W	1.145	1.00
250_A	254_A	1.143	1.00
456_S	460_D	1.140	1.00
301_F	464_A	1.139	1.00
246_G	442_A	1.139	1.00
91_T	179_E	1.133	1.00
358_R	387_M	1.131	0.99
270_A	437_I	1.127	0.99
101_R	104_D	1.113	0.99
267_V	433_A	1.111	0.99
263_R	491_A	1.104	0.99
483_V	510_L	1.103	0.99
273_S	484_R	1.102	0.99
120_D	160_D	1.100	0.99
244_R	274_R	1.098	0.99
329_N	401_T	1.097	0.99
485_A	506_M	1.097	0.99
278_L	481_L	1.087	0.99
377_A	380_T	1.085	0.99
257_T	261_A	1.082	0.99
144_L	322_H	1.081	0.99
258_A	489_V	1.080	0.99
52_S	55_K	1.074	0.99
50_L	57_P	1.073	0.99
299_Y	317_T	1.071	0.99
290_A	515_R	1.071	0.99
287_L	311_V	1.071	0.99
171_P	444_P	1.070	0.99
124_R	127_S	1.069	0.99
258_A	267_V	1.069	0.99
295_N	313_A	1.064	0.99
318_L	328_T	1.064	0.99
159_Y	438_D	1.063	0.99
499_Y	502_T	1.063	0.99
198_L	224_Q	1.063	0.99
87_A	184_T	1.055	0.99
161_L	420_F	1.055	0.99
285_R	302_L	1.054	0.99
275_T	482_T	1.050	0.99
125_L	180_F	1.047	0.99
280_G	287_L	1.042	0.99
198_L	223_V	1.037	0.99
88_A	128_V	1.037	0.99
185_R	200_C	1.035	0.99
288_Y	292_R	1.035	0.99
52_S	56_T	1.034	0.99
346_R	349_G	1.034	0.99
312_G	452_V	1.030	0.99
332_A	424_T	1.027	0.99
256_E	260_T	1.027	0.99
172_P	443_T	1.027	0.99
279_D	479_D	1.026	0.99
271_V	426_S	1.025	0.99
274_R	499_Y	1.023	0.99
173_T	482_T	1.021	0.99
93_D	96_D	1.019	0.99
321_V	412_A	1.011	0.99
487_A	497_A	1.001	0.99
126_R	417_R	1.001	0.99
451_G	463_L	0.998	0.99
297_S	394_H	0.993	0.99
452_V	466_T	0.993	0.99
242_T	510_L	0.990	0.99
284_P	302_L	0.987	0.99
180_F	463_L	0.986	0.99
87_A	182_V	0.986	0.99
83_G	150_V	0.986	0.99
483_V	506_M	0.985	0.99
300_M	313_A	0.985	0.99
511_A	514_D	0.984	0.99
274_R	503_E	0.978	0.99
123_D	127_S	0.977	0.99
214_D	218_A	0.977	0.99
86_P	183_T	0.974	0.98
348_A	396_Q	0.973	0.98
158_V	434_M	0.968	0.98
324_D	408_A	0.966	0.98
85_D	185_R	0.965	0.98
266_E	432_R	0.964	0.98
507_D	511_A	0.963	0.98
307_D	473_T	0.961	0.98
243_E	277_E	0.960	0.98
270_A	436_H	0.959	0.98
169_E	438_D	0.959	0.98
438_D	444_P	0.958	0.98
153_L	180_F	0.957	0.98
45_D	49_L	0.957	0.98
332_A	364_L	0.951	0.98
336_Q	504_A	0.950	0.98
157_A	178_A	0.949	0.98
321_V	406_L	0.943	0.98
65_F	183_T	0.941	0.98
332_A	361_H	0.941	0.98
145_L	150_V	0.939	0.98
327_V	401_T	0.938	0.98
187_L	196_V	0.938	0.98
179_E	305_H	0.938	0.98
219_E	222_R	0.937	0.98
220_A	224_Q	0.937	0.98
145_L	148_G	0.935	0.98
276_R	503_E	0.933	0.98
186_T	199_V	0.931	0.98
175_L	471_T	0.931	0.98
252_T	494_D	0.931	0.98
364_L	424_T	0.924	0.98
159_Y	167_G	0.922	0.98
280_G	481_L	0.921	0.98
297_S	300_M	0.921	0.98
271_V	425_L	0.920	0.98
295_N	394_H	0.920	0.98
166_V	435_E	0.919	0.98
93_D	177_D	0.919	0.98
175_L	308_H	0.915	0.98
53_A	189_F	0.911	0.98
54_E	302_L	0.907	0.98
412_A	461_A	0.904	0.98
425_L	467_I	0.904	0.98
317_T	327_V	0.899	0.97
122_L	157_A	0.896	0.97
123_D	126_R	0.891	0.97
259_A	491_A	0.890	0.97
50_L	189_F	0.887	0.97
154_A	177_D	0.885	0.97
361_H	364_L	0.882	0.97
373_R	378_P	0.881	0.97
352_L	389_V	0.879	0.97
336_Q	497_A	0.875	0.97
335_C	347_L	0.875	0.97
81_F	186_T	0.875	0.97
422_A	464_A	0.875	0.97
79_Y	188_V	0.873	0.97
68_D	288_Y	0.872	0.97
61_P	85_D	0.869	0.97
244_R	502_T	0.864	0.97
271_V	449_G	0.861	0.97
213_Y	216_L	0.859	0.97
153_L	178_A	0.859	0.97
90_V	124_R	0.858	0.97
318_L	419_A	0.858	0.97
259_A	263_R	0.855	0.97
156_D	159_Y	0.854	0.97
179_E	308_H	0.851	0.96
349_G	352_L	0.850	0.96
92_V	97_T	0.848	0.96
261_A	435_E	0.848	0.96
256_E	263_R	0.846	0.96
222_R	226_V	0.844	0.96
130_P	411_D	0.843	0.96
335_C	357_E	0.842	0.96
336_Q	347_L	0.841	0.96
416_T	461_A	0.840	0.96
159_Y	166_V	0.839	0.96
290_A	516_L	0.838	0.96
240_V	279_D	0.835	0.96
351_M	389_V	0.834	0.96
288_Y	311_V	0.831	0.96
157_A	160_D	0.827	0.96
343_A	347_L	0.822	0.96
49_L	52_S	0.820	0.96
432_R	436_H	0.818	0.96
153_L	463_L	0.817	0.96
392_Y	399_E	0.817	0.96
323_D	460_D	0.816	0.96
308_H	473_T	0.815	0.95
328_T	419_A	0.813	0.95
50_L	53_A	0.813	0.95
162_W	374_R	0.808	0.95
53_A	227_L	0.806	0.95
53_A	57_P	0.806	0.95
153_L	416_T	0.806	0.95
61_P	304_A	0.806	0.95
78_R	192_A	0.806	0.95
310_V	452_V	0.803	0.95
326_V	415_A	0.803	0.95
212_V	216_L	0.798	0.95
175_L	447_I	0.797	0.95
162_W	431_V	0.794	0.95
276_R	510_L	0.793	0.95
246_G	250_A	0.793	0.95
92_V	160_D	0.792	0.95
84_Y	185_R	0.789	0.95
160_D	177_D	0.788	0.95
252_T	255_V	0.786	0.95
258_A	440_I	0.784	0.94
309_T	472_I	0.781	0.94
152_F	447_I	0.779	0.94
385_E	401_T	0.779	0.94
361_H	449_G	0.778	0.94
224_Q	228_R	0.778	0.94
91_T	100_T	0.776	0.94
310_V	466_T	0.775	0.94
59_S	304_A	0.774	0.94
270_A	433_A	0.773	0.94
470_G	483_V	0.771	0.94
72_E	77_A	0.771	0.94
328_T	372_V	0.770	0.94
383_V	386_F	0.770	0.94
92_V	178_A	0.769	0.94
93_D	98_T	0.765	0.94
354_D	497_A	0.765	0.94
329_N	388_R	0.761	0.94
336_Q	339_A	0.761	0.94
150_V	303_L	0.759	0.93
217_E	221_K	0.758	0.93
317_T	329_N	0.758	0.93
132_V	457_W	0.758	0.93
380_T	405_T	0.758	0.93
394_H	508_G	0.758	0.93
212_V	215_A	0.757	0.93
361_H	368_A	0.753	0.93
368_A	422_A	0.752	0.93
49_L	54_E	0.751	0.93
167_G	438_D	0.750	0.93
245_A	274_R	0.749	0.93
368_A	464_A	0.749	0.93
275_T	443_T	0.746	0.93
216_L	227_L	0.741	0.93
161_L	417_R	0.740	0.93
358_R	386_F	0.738	0.92
174_P	473_T	0.737	0.92
158_V	161_L	0.736	0.92
472_I	479_D	0.736	0.92
214_D	217_E	0.735	0.92
245_A	277_E	0.734	0.92
249_D	252_T	0.731	0.92
321_V	461_A	0.731	0.92
218_A	222_R	0.729	0.92
173_T	444_P	0.728	0.92
254_A	258_A	0.727	0.92
335_C	504_A	0.726	0.92
425_L	465_I	0.725	0.92
361_H	424_T	0.724	0.92
49_L	189_F	0.724	0.92
324_D	377_A	0.721	0.92
420_F	465_I	0.721	0.92
281_D	479_D	0.721	0.92
393_S	508_G	0.720	0.92
276_R	485_A	0.716	0.91
433_A	488_G	0.716	0.91
305_H	308_H	0.715	0.91
128_V	131_A	0.715	0.91
361_H	396_Q	0.715	0.91
275_T	484_R	0.712	0.91
169_E	172_P	0.712	0.91
335_C	396_Q	0.712	0.91
336_Q	500_E	0.711	0.91
85_D	219_E	0.710	0.91
318_L	368_A	0.709	0.91
388_R	401_T	0.709	0.91
127_S	130_P	0.708	0.91
271_V	368_A	0.707	0.91
295_N	508_G	0.707	0.91
167_G	444_P	0.707	0.91
285_R	289_D	0.706	0.91
88_A	182_V	0.704	0.91
358_R	398_I	0.703	0.91
87_A	149_L	0.702	0.90
368_A	449_G	0.700	0.90
350_E	353_A	0.700	0.90
46_H	51_E	0.696	0.90
68_D	300_M	0.695	0.90
357_E	497_A	0.695	0.90
254_A	272_V	0.693	0.90
126_R	413_F	0.692	0.90
101_R	115_D	0.691	0.90
319_V	415_A	0.691	0.90
258_A	437_I	0.690	0.90
340_S	346_R	0.690	0.90
144_L	320_A	0.689	0.90
254_A	442_A	0.686	0.89
173_T	275_T	0.686	0.89
436_H	439_A	0.686	0.89
318_L	332_A	0.686	0.89
45_D	51_E	0.684	0.89
273_S	486_G	0.684	0.89
352_L	358_R	0.684	0.89
87_A	457_W	0.682	0.89
159_Y	177_D	0.676	0.89
255_V	487_A	0.676	0.89
455_F	461_A	0.675	0.89
255_V	259_A	0.673	0.89
326_V	406_L	0.671	0.88
262_V	491_A	0.669	0.88
303_L	452_V	0.669	0.88
294_V	394_H	0.668	0.88
138_P	141_D	0.668	0.88
405_T	408_A	0.668	0.88
225_A	229_D	0.666	0.88
171_P	275_T	0.664	0.88
274_R	469_S	0.661	0.88
96_D	118_T	0.660	0.88
443_T	484_R	0.657	0.87
271_V	422_A	0.657	0.87
267_V	436_H	0.657	0.87
81_F	150_V	0.656	0.87
359_A	492_D	0.655	0.87
472_I	478_E	0.655	0.87
422_A	425_L	0.655	0.87
318_L	361_H	0.655	0.87
215_A	218_A	0.654	0.87
187_L	198_L	0.653	0.87
272_V	440_I	0.653	0.87
145_L	462_E	0.650	0.87
51_E	289_D	0.649	0.87
364_L	487_A	0.647	0.87
176_P	308_H	0.647	0.87
221_K	224_Q	0.647	0.87
216_L	220_A	0.647	0.87
222_R	225_A	0.646	0.86
153_L	453_G	0.646	0.86
321_V	324_D	0.646	0.86
251_Y	502_T	0.645	0.86
512_A	516_L	0.643	0.86
326_V	404_G	0.642	0.86
89_V	181_A	0.641	0.86
92_V	121_V	0.640	0.86
60_D	304_A	0.640	0.86
422_A	449_G	0.640	0.86
324_D	406_L	0.639	0.86
312_G	422_A	0.638	0.86
473_T	479_D	0.638	0.86
116_H	119_G	0.637	0.86
64_A	304_A	0.634	0.85
271_V	312_G	0.634	0.85
266_E	370_N	0.632	0.85
411_D	414_D	0.631	0.85
382_S	405_T	0.626	0.85
310_V	469_S	0.623	0.84
169_E	444_P	0.621	0.84
287_L	481_L	0.621	0.84
294_V	511_A	0.620	0.84
358_R	362_T	0.619	0.84
329_N	392_Y	0.618	0.84
223_V	227_L	0.616	0.84
312_G	425_L	0.616	0.84
318_L	364_L	0.616	0.84
342_V	345_R	0.615	0.84
422_A	433_A	0.613	0.83
373_R	376_S	0.613	0.83
92_V	177_D	0.613	0.83
63_G	179_E	0.612	0.83
57_P	82_V	0.612	0.83
419_A	464_A	0.610	0.83
332_A	487_A	0.608	0.83
301_F	422_A	0.608	0.83
389_V	396_Q	0.607	0.83
271_V	464_A	0.607	0.83
271_V	433_A	0.607	0.83
350_E	354_D	0.606	0.83
431_V	435_E	0.605	0.83
506_M	510_L	0.604	0.83
361_H	365_V	0.603	0.82
284_P	304_A	0.602	0.82
352_L	355_E	0.601	0.82
201_T	457_W	0.601	0.82
128_V	149_L	0.600	0.82
241_T	514_D	0.599	0.82
301_F	469_S	0.598	0.82
306_G	309_T	0.596	0.82
54_E	82_V	0.593	0.81
122_L	161_L	0.592	0.81
100_T	103_R	0.592	0.81
195_S	293_A	0.591	0.81
259_A	495_P	0.591	0.81
148_G	457_W	0.591	0.81
489_V	497_A	0.590	0.81
412_A	459_G	0.589	0.81
328_T	402_V	0.589	0.81
503_E	507_D	0.588	0.81
291_L	509_V	0.587	0.81
471_T	482_T	0.587	0.81
79_Y	144_L	0.586	0.81
202_P	216_L	0.584	0.80
367_L	423_G	0.584	0.80
219_E	226_V	0.584	0.80
357_E	424_T	0.583	0.80
99_I	104_D	0.581	0.80
449_G	464_A	0.581	0.80
420_F	449_G	0.581	0.80
510_L	514_D	0.581	0.80
81_F	454_Y	0.580	0.80
374_R	431_V	0.579	0.80
303_L	310_V	0.579	0.80
96_D	116_H	0.578	0.80
152_F	308_H	0.578	0.80
301_F	311_V	0.577	0.80
361_H	400_S	0.577	0.80
70_T	73_E	0.577	0.80
269_Q	433_A	0.575	0.79
177_D	444_P	0.575	0.79
171_P	473_T	0.574	0.79
244_R	485_A	0.573	0.79
221_K	225_A	0.573	0.79
424_T	487_A	0.572	0.79
258_A	436_H	0.571	0.79
93_D	176_P	0.569	0.79
247_D	252_T	0.569	0.79
431_V	434_M	0.568	0.79
95_D	160_D	0.567	0.78
153_L	420_F	0.566	0.78
186_T	456_S	0.566	0.78
273_S	502_T	0.566	0.78
487_A	506_M	0.565	0.78
259_A	490_V	0.564	0.78
53_A	187_L	0.563	0.78
183_T	186_T	0.563	0.78
155_Y	426_S	0.562	0.78
336_Q	343_A	0.561	0.78
80_S	484_R	0.560	0.78
337_R	391_K	0.560	0.78
244_R	247_D	0.559	0.77
122_L	417_R	0.559	0.77
425_L	509_V	0.558	0.77
335_C	354_D	0.557	0.77
511_A	515_R	0.555	0.77
244_R	499_Y	0.554	0.77
297_S	508_G	0.553	0.77
61_P	84_Y	0.553	0.77
485_A	502_T	0.552	0.77
345_R	391_K	0.550	0.76
169_E	442_A	0.550	0.76
246_G	274_R	0.550	0.76
366_D	369_R	0.550	0.76
290_A	514_D	0.549	0.76
185_R	198_L	0.549	0.76
54_E	285_R	0.548	0.76
55_K	285_R	0.548	0.76
370_N	374_R	0.548	0.76
311_V	470_G	0.547	0.76
312_G	449_G	0.547	0.76
375_V	415_A	0.545	0.76
244_R	276_R	0.544	0.76
271_V	397_H	0.544	0.76
247_D	274_R	0.544	0.76
387_M	398_I	0.542	0.75
397_H	488_G	0.541	0.75
252_T	499_Y	0.540	0.75
269_Q	490_V	0.538	0.75
348_A	352_L	0.537	0.75
470_G	512_A	0.537	0.75
259_A	492_D	0.536	0.75
146_D	456_S	0.535	0.74
312_G	368_A	0.535	0.74
173_T	446_G	0.535	0.74
216_L	219_E	0.534	0.74
366_D	371_D	0.534	0.74
435_E	439_A	0.534	0.74
504_A	507_D	0.533	0.74
152_F	420_F	0.533	0.74
262_V	295_N	0.532	0.74
342_V	408_A	0.532	0.74
158_V	438_D	0.530	0.74
211_D	215_A	0.530	0.74
296_P	313_A	0.529	0.74
357_E	487_A	0.528	0.73
271_V	301_F	0.527	0.73
158_V	271_V	0.527	0.73
364_L	368_A	0.527	0.73
90_V	97_T	0.527	0.73
274_R	485_A	0.526	0.73
319_V	419_A	0.526	0.73
357_E	364_L	0.526	0.73
130_P	349_G	0.525	0.73
97_T	124_R	0.524	0.73
313_A	509_V	0.522	0.73
172_P	275_T	0.521	0.72
508_G	512_A	0.521	0.72
335_C	338_G	0.520	0.72
373_R	381_V	0.519	0.72
51_E	66_T	0.519	0.72
327_V	384_P	0.519	0.72
165_E	169_E	0.519	0.72
158_V	424_T	0.517	0.72
154_A	157_A	0.517	0.72
272_V	502_T	0.515	0.72
119_G	123_D	0.515	0.72
269_Q	361_H	0.514	0.71
262_V	267_V	0.514	0.71
273_S	424_T	0.514	0.71
239_E	281_D	0.513	0.71
175_L	446_G	0.513	0.71
318_L	424_T	0.513	0.71
268_Y	378_P	0.512	0.71
224_Q	231_T	0.512	0.71
370_N	492_D	0.511	0.71
99_I	114_P	0.510	0.71
466_T	469_S	0.509	0.71
326_V	375_V	0.509	0.71
70_T	392_Y	0.507	0.70
79_Y	152_F	0.507	0.70
298_P	435_E	0.506	0.70
344_D	396_Q	0.506	0.70
145_L	186_T	0.506	0.70
130_P	133_P	0.506	0.70
369_R	428_A	0.506	0.70
47_A	50_L	0.506	0.70
368_A	433_A	0.505	0.70
368_A	424_T	0.505	0.70
82_V	187_L	0.503	0.70
211_D	214_D	0.502	0.70
128_V	132_V	0.501	0.70
73_E	77_A	0.501	0.70
282_I	287_L	0.501	0.70
492_D	513_V	0.500	0.69
294_V	512_A	0.500	0.69

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1i1qA	2	0.8937	100	0.254	Contact Map
1k0eA	1	0.8311	100	0.257	Contact Map
4grhA	1	0.8254	100	0.279	Contact Map
1qdlA	1	0.7875	100	0.28	Contact Map
3logA	1	0.8482	100	0.325	Contact Map
3h9mA	1	0.7457	100	0.327	Contact Map
2fn0A	2	0.7799	100	0.363	Contact Map
3gseA	1	0.7837	100	0.42	Contact Map
3bzmA	1	0.8065	100	0.454	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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