GREMLIN Database
CDCH - Protein CdcH
UniProt: Q9HPF0 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 742 (606)
Sequences: 112 (70)
Seq/√Len: 2.9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
326_V329_I3.9610.69
285_I658_L3.4940.59
558_V626_V3.4840.59
215_F218_L3.3970.57
485_P507_T3.0280.48
336_D663_D2.9840.46
507_T534_S2.9210.45
226_V254_I2.8780.44
452_V521_N2.8520.43
535_K585_N2.8390.43
142_R148_I2.8200.42
636_R662_A2.8040.42
253_S658_L2.7720.41
185_G188_Y2.6910.39
245_N650_A2.6000.37
526_S529_G2.5990.37
529_G582_R2.5820.37
513_A524_F2.5660.37
530_P586_Q2.4430.34
529_G584_V2.4370.34
604_A636_R2.3480.32
241_K729_N2.3300.31
521_N603_I2.3230.31
471_K565_D2.3180.31
143_S147_A2.3180.31
152_A158_E2.3120.31
303_G507_T2.3040.31
186_I189_E2.2840.30
631_P636_R2.2570.30
643_H695_H2.2270.29
465_G523_N2.2000.29
591_L664_G2.1990.29
607_N628_V2.1620.28
120_L125_V2.1570.28
626_V707_I2.1500.28
492_G607_N2.1360.27
588_L616_L2.1070.27
143_S146_Q2.1050.27
184_G189_E2.0990.27
185_G189_E2.0790.26
487_K591_L2.0370.26
116_K119_I2.0250.25
467_L669_D2.0240.25
537_V611_I2.0060.25
487_K671_A1.9600.24
626_V682_L1.9570.24
564_L607_N1.9370.24
122_R135_S1.9370.24
528_R531_Q1.9360.24
325_Q333_N1.9300.24
551_A560_F1.9190.23
551_A562_D1.9190.23
551_A563_E1.9190.23
560_F563_E1.9190.23
235_G623_D1.9130.23
436_D626_V1.8910.23
547_T570_G1.8870.23
608_R639_I1.8660.22
470_A487_K1.8610.22
268_E286_I1.8600.22
278_A653_V1.8570.22
529_G669_D1.8480.22
485_P504_P1.8410.22
666_V715_Y1.8380.22
526_S572_G1.8370.22
161_C692_G1.8300.22
588_L623_D1.8270.22
616_L623_D1.8270.22
664_G715_Y1.8230.22
651_A692_G1.8170.22
324_G331_A1.8170.22
463_D565_D1.8160.22
507_T625_L1.7900.21
259_I487_K1.7890.21
699_A705_P1.7850.21
609_P669_D1.7790.21
328_V331_A1.7760.21
120_L129_I1.7740.21
143_S152_A1.7670.21
487_K570_G1.7660.21
526_S582_R1.7530.21
535_K631_P1.7500.21
591_L715_Y1.7490.21
585_N631_P1.7410.20
528_R584_V1.7350.20
572_G582_R1.7200.20
235_G588_L1.7170.20
235_G616_L1.7170.20
122_R130_V1.7160.20
511_L526_S1.7140.20
477_S496_P1.7100.20
125_V135_S1.7090.20
182_T188_Y1.6880.20
481_P706_T1.6880.20
499_V527_V1.6860.20
271_L286_I1.6800.19
522_A576_G1.6770.19
483_N612_I1.6760.19
561_F584_V1.6760.19
125_V128_D1.6700.19
514_K628_V1.6660.19
567_L662_A1.6640.19
119_I125_V1.6630.19
529_G572_G1.6620.19
537_V581_E1.6600.19
508_G548_F1.6590.19
155_T170_E1.6560.19
485_P591_L1.6380.19
662_A670_L1.6360.19
467_L481_P1.6350.19
348_F403_A1.6330.19
184_G188_Y1.6060.18
209_M558_V1.5950.18
116_K120_L1.5870.18
293_S527_V1.5650.18
391_F493_V1.5640.18
565_D664_G1.5590.18
494_E572_G1.5540.18
531_Q584_V1.5540.18
564_L628_V1.5440.17
182_T185_G1.5420.17
636_R659_A1.5370.17
542_K678_A1.5360.17
542_K691_V1.5270.17
499_V714_Y1.5230.17
142_R146_Q1.5170.17
525_I535_K1.5160.17
530_P584_V1.5150.17
158_E168_D1.5120.17
518_N612_I1.5100.17
514_K607_N1.4990.17
639_I667_G1.4920.17
531_Q582_R1.4870.17
718_V726_Q1.4870.17
615_A631_P1.4830.17
122_R132_V1.4820.17
545_R581_E1.4800.17
532_L567_L1.4740.16
464_V662_A1.4710.16
470_A591_L1.4590.16
537_V628_V1.4490.16
165_E170_E1.4420.16
159_G173_E1.4410.16
550_K554_V1.4150.16
168_D171_L1.4120.16
591_L666_V1.4120.16
494_E580_S1.4040.16
122_R127_R1.4040.16
607_N719_E1.4040.16
290_E519_E1.4010.16
589_T604_A1.3920.15
433_K655_L1.3860.15
291_L604_A1.3830.15
339_D432_V1.3810.15
143_S148_I1.3770.15
569_P579_V1.3700.15
530_P545_R1.3640.15
165_E168_D1.3630.15
580_S585_N1.3620.15
116_K125_V1.3570.15
461_W497_A1.3530.15
483_N567_L1.3510.15
675_R679_I1.3510.15
449_M452_V1.3470.15
517_A605_A1.3460.15
487_K507_T1.3370.15
176_I558_V1.3340.15
466_G588_L1.3260.15
466_G616_L1.3260.15
156_E176_I1.3250.15
531_Q581_E1.3240.15
427_I692_G1.3230.15
307_R657_E1.3200.15
118_Q123_P1.3190.14
655_L663_D1.3170.14
443_E559_I1.3130.14
676_E679_I1.3110.14
347_R527_V1.3090.14
542_K558_V1.3090.14
468_T471_K1.3040.14
559_I607_N1.2980.14
130_V136_T1.2950.14
111_A118_Q1.2830.14
481_P669_D1.2810.14
565_D642_I1.2760.14
395_D595_E1.2740.14
523_N610_D1.2730.14
452_V603_I1.2710.14
152_A170_E1.2710.14
467_L582_R1.2700.14
545_R588_L1.2700.14
545_R616_L1.2700.14
561_F586_Q1.2630.14
117_R122_R1.2580.14
530_P561_F1.2570.14
494_E526_S1.2530.14
240_A290_E1.2520.14
478_V520_T1.2520.14
644_T722_F1.2500.14
325_Q331_A1.2490.14
467_L566_S1.2490.14
566_S582_R1.2450.14
486_E534_S1.2440.14
214_I218_L1.2430.14
603_I715_Y1.2370.14
120_L123_P1.2310.13
109_S116_K1.2300.13
183_G245_N1.2290.13
119_I129_I1.2280.13
719_E722_F1.2270.13
150_L153_V1.2230.13
474_V525_I1.2230.13
574_T628_V1.2200.13
314_L682_L1.2190.13
467_L523_N1.2170.13
331_A532_L1.2140.13
464_V604_A1.2140.13
245_N366_L1.2140.13
539_E590_E1.2130.13
236_K623_D1.2070.13
166_D181_R1.2000.13
119_I122_R1.1990.13
552_R590_E1.1960.13
569_P586_Q1.1960.13
234_T601_M1.1890.13
536_W588_L1.1860.13
536_W616_L1.1860.13
530_P569_P1.1850.13
545_R586_Q1.1800.13
328_V332_T1.1790.13
547_T629_G1.1790.13
285_I565_D1.1780.13
399_L450_R1.1750.13
535_K636_R1.1730.13
514_K559_I1.1690.13
585_N636_R1.1610.13
467_L608_R1.1570.13
484_Q599_E1.1570.13
559_I628_V1.1550.13
533_L617_I1.1530.13
152_A159_G1.1490.13
285_I614_P1.1450.13
591_L594_L1.1450.13
581_E588_L1.1440.12
581_E616_L1.1440.12
666_V727_G1.1410.12
530_P611_I1.1400.12
123_P133_M1.1400.12
467_L609_P1.1360.12
116_K126_A1.1350.12
539_E607_N1.1350.12
586_Q611_I1.1310.12
599_E607_N1.1270.12
501_L631_P1.1270.12
163_V170_E1.1250.12
329_I344_R1.1240.12
507_T532_L1.1170.12
312_Q648_P1.1160.12
569_P611_I1.1160.12
447_S632_G1.1150.12
450_R612_I1.1140.12
551_A556_P1.1130.12
556_P560_F1.1130.12
556_P562_D1.1130.12
556_P563_E1.1130.12
244_A542_K1.1020.12
164_T356_V1.1000.12
467_L706_T1.0980.12
405_M573_Q1.0970.12
468_T565_D1.0970.12
261_S507_T1.0950.12
269_Q272_R1.0910.12
578_N611_I1.0910.12
516_V663_D1.0780.12
546_Q678_A1.0760.12
488_F526_S1.0750.12
482_L507_T1.0740.12
538_G541_E1.0680.12
331_A340_P1.0660.12
324_G329_I1.0630.12
403_A534_S1.0630.12
448_A587_L1.0630.12
131_P134_S1.0610.12
581_E611_I1.0590.12
253_S507_T1.0560.12
569_P584_V1.0550.12
414_E692_G1.0540.12
564_L599_E1.0520.12
723_K726_Q1.0460.11
228_L348_F1.0460.11
339_D682_L1.0450.11
466_G623_D1.0420.11
531_Q586_Q1.0420.11
558_V691_V1.0410.11
389_H580_S1.0350.11
526_S584_V1.0350.11
671_A728_P1.0310.11
474_V535_K1.0260.11
147_A151_I1.0250.11
159_G164_T1.0250.11
312_Q649_L1.0250.11
474_V585_N1.0250.11
474_V631_P1.0170.11
539_E580_S1.0170.11
494_E547_T1.0150.11
270_Q327_I1.0140.11
151_I157_P1.0120.11
129_I136_T1.0070.11
537_V578_N1.0070.11
540_S579_V1.0060.11
603_I625_L1.0060.11
532_L591_L1.0050.11
462_D699_A1.0040.11
114_M134_S1.0030.11
532_L572_G1.0020.11
432_V437_F1.0010.11
232_P361_G0.9960.11
485_P699_A0.9920.11
504_P664_G0.9910.11
149_P169_V0.9880.11
212_P217_K0.9860.11
271_L334_R0.9860.11
504_P507_T0.9820.11
236_K588_L0.9780.11
236_K616_L0.9780.11
500_L503_G0.9780.11
500_L506_G0.9780.11
500_L509_K0.9780.11
500_L510_T0.9780.11
500_L571_R0.9780.11
500_L593_G0.9780.11
500_L613_D0.9780.11
500_L621_R0.9780.11
503_G506_G0.9780.11
503_G509_K0.9780.11
503_G510_T0.9780.11
503_G571_R0.9780.11
503_G593_G0.9780.11
503_G613_D0.9780.11
503_G621_R0.9780.11
506_G509_K0.9780.11
506_G510_T0.9780.11
506_G571_R0.9780.11
506_G593_G0.9780.11
506_G613_D0.9780.11
506_G621_R0.9780.11
509_K571_R0.9780.11
509_K593_G0.9780.11
509_K613_D0.9780.11
509_K621_R0.9780.11
510_T571_R0.9780.11
510_T593_G0.9780.11
510_T613_D0.9780.11
510_T621_R0.9780.11
571_R593_G0.9780.11
571_R613_D0.9780.11
571_R621_R0.9780.11
593_G613_D0.9780.11
593_G621_R0.9780.11
613_D621_R0.9780.11
313_L710_D0.9770.11
545_R623_D0.9740.11
502_Y545_R0.9740.11
582_R669_D0.9730.11
271_L285_I0.9720.11
184_G187_T0.9710.11
474_V603_I0.9710.11
124_V128_D0.9710.11
255_A656_R0.9680.11
357_P511_L0.9680.11
504_P591_L0.9640.11
466_G569_P0.9610.11
492_G564_L0.9610.11
119_I128_D0.9600.11
570_G671_A0.9580.11
159_G170_E0.9570.11
530_P568_A0.9560.11
515_A664_G0.9550.11
528_R582_R0.9540.11
568_A586_Q0.9530.11
279_K342_L0.9520.11
476_E493_V0.9500.11
537_V564_L0.9500.11
434_R489_T0.9490.11
452_V464_V0.9490.11
168_D173_E0.9470.11
158_E169_V0.9470.11
528_R586_Q0.9460.11
611_I628_V0.9460.11
551_A636_R0.9450.11
560_F636_R0.9450.11
562_D636_R0.9450.11
563_E636_R0.9450.11
230_G236_K0.9450.11
117_R124_V0.9430.10
278_A695_H0.9390.10
124_V133_M0.9380.10
160_V174_E0.9380.10
601_M612_I0.9380.10
318_D490_R0.9370.10
582_R586_Q0.9370.10
146_Q153_V0.9370.10
114_M118_Q0.9370.10
480_W514_K0.9350.10
166_D173_E0.9340.10
567_L612_I0.9310.10
339_D714_Y0.9300.10
243_V329_I0.9300.10
484_Q564_L0.9300.10
465_G608_R0.9300.10
650_A653_V0.9290.10
244_A696_F0.9290.10
307_R661_R0.9290.10
665_Y674_A0.9280.10
354_I453_L0.9200.10
440_A511_L0.9200.10
209_M570_G0.9200.10
235_G466_G0.9170.10
462_D656_R0.9170.10
531_Q611_I0.9130.10
114_M126_A0.9130.10
325_Q328_V0.9120.10
118_Q125_V0.9120.10
223_P376_S0.9100.10
535_K669_D0.9100.10
265_G268_E0.9100.10
569_P578_N0.9070.10
357_P499_V0.9050.10
126_A129_I0.9040.10
486_E507_T0.9030.10
391_F514_K0.9020.10
160_V170_E0.9000.10
502_Y536_W0.8980.10
522_A578_N0.8950.10
166_D172_R0.8950.10
715_Y725_S0.8950.10
153_V158_E0.8950.10
554_V557_T0.8920.10
564_L577_N0.8910.10
536_W623_D0.8910.10
402_E554_V0.8890.10
482_L607_N0.8880.10
551_A565_D0.8870.10
560_F565_D0.8870.10
562_D565_D0.8870.10
467_L667_G0.8870.10
502_Y588_L0.8820.10
502_Y616_L0.8820.10
352_I378_D0.8760.10
444_V448_A0.8760.10
495_P534_S0.8750.10
239_L527_V0.8740.10
636_R670_L0.8740.10
537_V569_P0.8720.10
561_F722_F0.8710.10
440_A572_G0.8710.10
171_L174_E0.8690.10
487_K514_K0.8690.10
464_V521_N0.8680.10
566_S572_G0.8670.10
547_T682_L0.8620.10
118_Q122_R0.8600.10
541_E585_N0.8590.10
183_G194_L0.8560.10
538_G556_P0.8560.10
540_S545_R0.8550.10
360_I645_Q0.8540.10
235_G545_R0.8510.10
531_Q537_V0.8510.10
270_Q276_E0.8500.10
644_T674_A0.8500.10
289_D539_E0.8480.10
499_V673_I0.8480.10
446_P612_I0.8470.10
167_T174_E0.8450.10
114_M117_R0.8440.10
581_E623_D0.8390.10
508_G524_F0.8380.10
524_F548_F0.8380.10
569_P588_L0.8340.10
569_P616_L0.8340.10
233_G677_A0.8250.09
139_P658_L0.8230.09
127_R133_M0.8230.09
403_A507_T0.8190.09
329_I333_N0.8170.09
355_G547_T0.8160.09
154_E159_G0.8140.09
536_W581_E0.8140.09
227_L436_D0.8110.09
533_L544_I0.8110.09
255_A710_D0.8100.09
624_R679_I0.8100.09
389_H607_N0.8100.09
528_R581_E0.8080.09
534_S671_A0.8060.09
646_D711_L0.8050.09
391_F487_K0.8040.09
133_M136_T0.8020.09
564_L719_E0.8020.09
607_N703_V0.8020.09
667_G706_T0.8010.09
523_N669_D0.8000.09
156_E172_R0.7990.09
481_P609_P0.7990.09
367_K612_I0.7970.09
514_K539_E0.7970.09
111_A115_V0.7960.09
514_K625_L0.7960.09
156_E174_E0.7950.09
324_G334_R0.7950.09
549_R587_L0.7930.09
599_E617_I0.7930.09
561_F569_P0.7910.09
205_V210_K0.7900.09
540_S588_L0.7900.09
540_S616_L0.7900.09
502_Y530_P0.7860.09
570_G682_L0.7860.09
573_Q628_V0.7860.09
471_K499_V0.7860.09
502_Y586_Q0.7850.09
532_L643_H0.7820.09
583_V620_G0.7820.09
553_Q665_Y0.7800.09
488_F669_D0.7800.09
317_M434_R0.7740.09
362_R569_P0.7710.09
117_R130_V0.7700.09
626_V642_I0.7680.09
184_G190_D0.7680.09
235_G536_W0.7670.09
478_V487_K0.7670.09
359_E665_Y0.7660.09
484_Q601_M0.7600.09
559_I564_L0.7600.09
727_G731_N0.7600.09
326_V336_D0.7570.09
269_Q275_F0.7570.09
233_G239_L0.7560.09
404_A532_L0.7560.09
478_V672_N0.7550.09
528_R557_T0.7550.09
545_R611_I0.7540.09
164_T171_L0.7540.09
278_A729_N0.7530.09
540_S584_V0.7530.09
480_W632_G0.7500.09
335_V532_L0.7500.09
487_K504_P0.7490.09
581_E586_Q0.7480.09
461_W569_P0.7470.09
127_R132_V0.7460.09
239_L701_E0.7430.09
466_G583_V0.7430.09
594_L703_V0.7430.09
595_E628_V0.7420.09
530_P581_E0.7420.09
604_A631_P0.7410.09
615_A636_R0.7410.09
608_R669_D0.7390.09
159_G168_D0.7380.09
525_I631_P0.7350.09
389_H628_V0.7340.09
440_A526_S0.7330.09
283_P526_S0.7320.09
130_V143_S0.7310.09
528_R611_I0.7300.09
528_R537_V0.7280.09
573_Q580_S0.7270.09
496_P601_M0.7260.09
454_V518_N0.7240.09
537_V584_V0.7240.09
355_G570_G0.7230.09
149_P162_L0.7210.09
125_V129_I0.7210.09
242_A534_S0.7190.09
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132_V135_S0.7180.09
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497_A619_S0.7170.09
671_A678_A0.7160.09
485_P532_L0.7150.09
437_F448_A0.7150.09
532_L715_Y0.7140.09
226_V707_I0.7130.09
544_I617_I0.7130.09
464_V603_I0.7110.09
288_I651_A0.7090.09
436_D516_V0.7060.09
235_G581_E0.7050.08
182_T658_L0.7050.08
234_T275_F0.7040.08
515_A524_F0.6990.08
625_L715_Y0.6990.08
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170_E173_E0.6950.08
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285_I429_R0.6930.08
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154_E157_P0.6920.08
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449_M464_V0.6910.08
172_R175_P0.6870.08
151_I154_E0.6850.08
504_P627_Q0.6850.08
345_P504_P0.6840.08
504_P594_L0.6820.08
261_S534_S0.6810.08
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570_G642_I0.6790.08
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325_Q342_L0.6770.08
367_K370_T0.6770.08
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129_I133_M0.6760.08
307_R645_Q0.6750.08
493_V547_T0.6750.08
534_S625_L0.6750.08
173_E626_V0.6730.08
133_M312_Q0.6720.08
553_Q630_Q0.6700.08
373_M696_F0.6670.08
546_Q672_N0.6670.08
348_F532_L0.6660.08
542_K683_R0.6650.08
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283_P523_N0.6520.08
618_R631_P0.6520.08
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476_E480_W0.6400.08
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585_N662_A0.6370.08
500_L551_A0.6360.08
500_L560_F0.6360.08
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551_A571_R0.6360.08
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151_I158_E0.6350.08
400_S403_A0.6340.08
487_K534_S0.6340.08
426_L443_E0.6330.08
448_A696_F0.6310.08
144_P149_P0.6300.08
464_V670_L0.6290.08
186_I196_N0.6290.08
505_P659_A0.6290.08
507_T598_E0.6280.08
228_L527_V0.6280.08
261_S479_E0.6270.08
328_V403_A0.6240.08
530_P537_V0.6240.08
608_R667_G0.6240.08
254_I441_L0.6220.08
537_V586_Q0.6220.08
142_R157_P0.6210.08
599_E628_V0.6210.08
112_A119_I0.6200.08
362_R365_I0.6190.08
523_N609_P0.6180.08
589_T612_I0.6160.08
467_L529_G0.6160.08
331_A335_V0.6150.08
183_G186_I0.6150.08
158_E161_C0.6140.08
576_G586_Q0.6140.08
457_P504_P0.6140.08
287_F369_H0.6110.08
482_L539_E0.6110.08
491_M726_Q0.6110.08
588_L620_G0.6100.08
616_L620_G0.6100.08
530_P576_G0.6090.08
428_D692_G0.6060.08
143_S149_P0.6050.08
336_D433_K0.6040.08
351_E464_V0.6040.08
292_D614_P0.6030.08
467_L639_I0.6030.08
552_R665_Y0.6020.08
711_L718_V0.6010.08
214_I217_K0.6010.08
144_P160_V0.6010.08
559_I595_E0.6010.08
148_I154_E0.6000.08
568_A574_T0.5990.08
483_N675_R0.5980.08
564_L611_I0.5970.08
430_M438_K0.5970.08
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540_S586_Q0.5960.08
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609_P639_I0.5950.08
109_S113_G0.5930.08
124_V127_R0.5930.08
534_S598_E0.5920.08
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117_R123_P0.5910.08
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519_E678_A0.5880.08
234_T387_D0.5870.08
155_T159_G0.5860.08
493_V715_Y0.5860.08
155_T692_G0.5860.08
390_G395_D0.5850.08
554_V578_N0.5830.08
612_I675_R0.5830.08
123_P134_S0.5820.08
226_V324_G0.5820.08
502_Y623_D0.5810.08
316_M428_D0.5800.08
115_V118_Q0.5800.08
498_G503_G0.5800.08
498_G506_G0.5800.08
498_G509_K0.5800.08
498_G510_T0.5800.08
498_G571_R0.5800.08
498_G593_G0.5800.08
498_G613_D0.5800.08
498_G621_R0.5800.08
230_G395_D0.5790.08
362_R561_F0.5780.08
624_R668_S0.5780.08
396_I478_V0.5760.08
150_L175_P0.5750.08
171_L307_R0.5740.08
243_V489_T0.5730.08
144_P158_E0.5720.08
496_P679_I0.5700.08
478_V504_P0.5690.08
545_R584_V0.5680.08
427_I634_E0.5650.07
521_N535_K0.5650.07
545_R568_A0.5650.07
561_F582_R0.5640.07
276_E320_L0.5630.07
530_P582_R0.5630.07
467_L541_E0.5620.07
577_N580_S0.5620.07
684_D695_H0.5610.07
450_R602_V0.5600.07
565_D661_R0.5600.07
282_S534_S0.5590.07
507_T672_N0.5590.07
540_S623_D0.5590.07
632_G635_G0.5590.07
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482_L494_E0.5570.07
601_M675_R0.5570.07
313_L430_M0.5560.07
226_V516_V0.5550.07
504_P514_K0.5540.07
536_W611_I0.5530.07
566_S667_G0.5530.07
537_V607_N0.5520.07
237_T502_Y0.5520.07
277_D385_A0.5520.07
111_A136_T0.5510.07
387_D558_V0.5500.07
526_S669_D0.5500.07
376_S414_E0.5490.07
674_A695_H0.5490.07
480_W522_A0.5460.07
511_L572_G0.5450.07
292_D705_P0.5450.07
519_E542_K0.5450.07
170_E285_I0.5430.07
329_I335_V0.5430.07
298_R699_A0.5420.07
130_V135_S0.5410.07
455_E699_A0.5400.07
577_N628_V0.5400.07
185_G190_D0.5390.07
492_G601_M0.5380.07
457_P492_G0.5360.07
622_F706_T0.5360.07
695_H715_Y0.5360.07
181_R190_D0.5350.07
577_N607_N0.5350.07
495_P726_Q0.5350.07
362_R540_S0.5340.07
268_E271_L0.5340.07
134_S365_I0.5330.07
157_P170_E0.5320.07
432_V436_D0.5320.07
212_P215_F0.5290.07
115_V125_V0.5280.07
529_G609_P0.5270.07
154_E172_R0.5260.07
369_H707_I0.5260.07
654_S658_L0.5260.07
502_Y599_E0.5250.07
465_G667_G0.5240.07
461_W496_P0.5240.07
561_F588_L0.5230.07
561_F616_L0.5230.07
477_S578_N0.5220.07
574_T597_M0.5220.07
465_G524_F0.5220.07
111_A117_R0.5210.07
405_M483_N0.5200.07
326_V330_A0.5180.07
569_P623_D0.5170.07
444_V449_M0.5170.07
712_M727_G0.5160.07
396_I576_G0.5150.07
124_V139_P0.5140.07
234_T464_V0.5140.07
168_D172_R0.5140.07
140_F143_S0.5140.07
455_E473_N0.5140.07
126_A130_V0.5130.07
226_V694_A0.5120.07
238_L315_T0.5110.07
265_G649_L0.5110.07
612_I624_R0.5110.07
466_G579_V0.5100.07
500_L592_D0.5090.07
503_G592_D0.5090.07
506_G592_D0.5090.07
509_K592_D0.5090.07
510_T592_D0.5090.07
571_R592_D0.5090.07
592_D613_D0.5090.07
592_D621_R0.5090.07
358_D445_E0.5080.07
551_A639_I0.5060.07
560_F639_I0.5060.07
562_D639_I0.5060.07
563_E639_I0.5060.07
111_A125_V0.5060.07
154_E162_L0.5060.07
153_V166_D0.5060.07
157_P160_V0.5060.07
488_F535_K0.5060.07
529_G561_F0.5050.07
540_S589_T0.5030.07
573_Q590_E0.5030.07
500_L618_R0.5030.07
503_G618_R0.5030.07
506_G618_R0.5030.07
509_K618_R0.5030.07
510_T618_R0.5030.07
571_R618_R0.5030.07
593_G618_R0.5030.07
613_D618_R0.5030.07
618_R621_R0.5030.07
464_V636_R0.5010.07
578_N588_L0.5010.07
578_N616_L0.5010.07
545_R561_F0.5010.07
540_S561_F0.5000.07
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3cf2A 3 0.8801 100 0.592 Contact Map
3cmuA 1 0.8032 100 0.711 Contact Map
4cr2J 1 0.4757 100 0.744 Contact Map
2x8aA 1 0.3127 100 0.756 Contact Map
4ko8A 3 0.5701 100 0.768 Contact Map
1xwiA 1 0.3666 100 0.77 Contact Map
4cr2L 1 0.4663 100 0.771 Contact Map
3cf0A 3 0.372 100 0.772 Contact Map
4cr2M 1 0.4528 100 0.775 Contact Map
2ce7A 3 0.3801 100 0.776 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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