GREMLIN Database
RS8E - 30S ribosomal protein S8e
UniProt: Q9HPE9 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 124 (120)
Sequences: 393 (242)
Seq/√Len: 22.1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
10_S14_A5.6591.00
76_D90_N4.3421.00
61_V119_A3.4431.00
92_I107_V3.3601.00
98_I119_A2.6960.99
95_G106_R2.6210.99
61_V98_I2.5790.98
65_T68_G2.4640.98
105_A119_A2.3720.97
24_K27_L2.3640.97
46_V50_A2.3210.97
109_S112_G1.9800.92
61_V105_A1.9460.92
107_V117_V1.9090.91
72_A101_D1.8520.90
79_A87_A1.8490.90
98_I117_V1.8340.89
100_T103_G1.8300.89
81_D93_T1.7840.88
80_N93_T1.7260.86
73_T101_D1.7180.86
88_R93_T1.6800.84
97_I106_R1.6230.82
43_T53_V1.6080.82
4_Q7_S1.5900.81
70_E73_T1.5640.80
45_D50_A1.5390.79
28_G34_T1.4180.73
64_A69_A1.4110.72
46_V51_E1.3630.70
109_S114_D1.3190.67
30_E106_R1.2900.65
80_N87_A1.2770.64
58_T117_V1.2600.63
63_V102_A1.2290.61
59_N73_T1.2190.61
44_V54_R1.2180.61
114_D118_N1.2080.60
32_T54_R1.2010.60
29_R44_V1.1900.59
61_V107_V1.1790.58
31_P34_T1.1770.58
25_S47_R1.1760.58
62_N106_R1.1330.55
3_Y8_K1.1270.55
94_K97_I1.1210.54
20_S23_S1.1210.54
84_P87_A1.1100.53
45_D49_D1.1080.53
58_T92_I1.0920.52
98_I105_A1.0770.51
6_R17_R1.0430.49
6_R16_L1.0430.49
7_S80_N1.0310.48
20_S26_E1.0260.48
99_E104_T1.0160.47
95_G103_G1.0130.47
80_N95_G0.9940.46
111_P115_G0.9890.45
70_E101_D0.9630.44
90_N95_G0.9520.43
61_V117_V0.9450.42
78_S104_T0.9400.42
66_D99_E0.9370.42
8_K58_T0.9330.42
118_N122_V0.9300.41
8_K16_L0.9200.41
60_V73_T0.9190.41
72_A102_A0.9150.40
79_A84_P0.9130.40
87_A90_N0.9070.40
37_G106_R0.9070.40
70_E97_I0.9030.40
4_Q22_K0.8820.38
36_V42_R0.8530.36
11_K14_A0.8510.36
82_A98_I0.8420.36
39_P59_N0.8390.35
75_E99_E0.8360.35
55_V62_N0.8350.35
29_R32_T0.8210.34
6_R11_K0.8040.33
32_T44_V0.7960.33
23_S34_T0.7920.33
72_A107_V0.7900.32
14_A19_R0.7890.32
52_K113_Q0.7880.32
94_K104_T0.7670.31
22_K28_G0.7630.31
71_R101_D0.7620.31
26_E62_N0.7570.31
30_E85_N0.7570.31
42_R62_N0.7570.31
17_R41_F0.7500.30
47_R54_R0.7420.30
95_G99_E0.7400.30
69_A92_I0.7360.29
20_S27_L0.7240.29
106_R120_T0.7150.28
44_V96_A0.7110.28
22_K30_E0.7060.28
12_T86_Y0.7030.27
54_R88_R0.7020.27
93_T98_I0.7010.27
55_V116_Q0.6950.27
79_A89_R0.6890.27
78_S88_R0.6820.26
89_R103_G0.6790.26
36_V74_I0.6640.25
109_S115_G0.6630.25
83_N114_D0.6620.25
104_T120_T0.6610.25
86_Y105_A0.6600.25
56_L116_Q0.6590.25
40_R57_S0.6570.25
19_R30_E0.6490.25
38_E59_N0.6400.24
7_S90_N0.6400.24
24_K94_K0.6240.23
116_Q120_T0.6180.23
83_N103_G0.6170.23
5_G30_E0.6160.23
56_L69_A0.6160.23
40_R93_T0.6130.23
108_T120_T0.6080.23
6_R81_D0.6070.23
24_K62_N0.6050.22
9_R74_I0.6030.22
56_L67_S0.5990.22
14_A73_T0.5980.22
55_V105_A0.5920.22
57_S84_P0.5900.22
38_E108_T0.5810.21
8_K57_S0.5730.21
6_R36_V0.5720.21
28_G105_A0.5680.21
6_R19_R0.5670.21
88_R92_I0.5660.21
41_F83_N0.5650.21
8_K67_S0.5650.21
28_G55_V0.5620.21
107_V113_Q0.5600.20
30_E91_I0.5550.20
75_E104_T0.5550.20
15_R84_P0.5540.20
39_P58_T0.5540.20
11_K67_S0.5530.20
28_G32_T0.5530.20
25_S36_V0.5520.20
79_A104_T0.5520.20
25_S69_A0.5490.20
93_T96_A0.5480.20
84_P88_R0.5440.20
18_P39_P0.5430.20
59_N86_Y0.5430.20
11_K90_N0.5420.20
68_G102_A0.5340.19
17_R27_L0.5320.19
55_V85_N0.5310.19
91_I107_V0.5290.19
43_T51_E0.5270.19
9_R26_E0.5240.19
3_Y7_S0.5240.19
6_R18_P0.5210.19
45_D75_E0.5200.19
64_A104_T0.5180.19
15_R65_T0.5180.19
42_R114_D0.5160.19
86_Y119_A0.5140.18
65_T102_A0.5140.18
37_G90_N0.5130.18
56_L90_N0.5100.18
49_D57_S0.5100.18
9_R54_R0.5080.18
10_S13_G0.5070.18
83_N95_G0.5070.18
38_E72_A0.5050.18
36_V77_V0.5020.18
57_S70_E0.5020.18
15_R54_R0.5000.18
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2kcoA 1 1 100 0.085 Contact Map
4ujpJ 1 1 100 0.086 Contact Map
3j20J 1 0.9919 100 0.087 Contact Map
3j60I 1 0.1694 100 0.116 Contact Map
4bpe2 1 1 100 0.118 Contact Map
3j7aL 1 0.9839 100 0.136 Contact Map
4w23I 1 1 100 0.147 Contact Map
3j38I 1 1 100 0.148 Contact Map
3zey5 1 1 100 0.15 Contact Map
2kcpA 1 0.7097 100 0.349 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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