Q9HPD8 - HALSA - GREMLIN Contacts

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Q9HPD8 - Phytoene dehydrogenase

UniProt:	Q9HPD8	Sequences: MDELAGTSVAVIGAGFGGLSTACYLADAGADVTVVEKTDQIGGRASTLERDGFRFDMGPSWYLMPDVFEEFFASFDSHPSDYYGLTRLDPHYRIFFKDNEGRRPGRDAPGLNVDTDGDTIDVTPDREQVKQVFDAYEPGAGDVLDDYLAQAKENYEVGMEHFVKTDRPRVRDWMDPKLAEYARGLTLLGSMQDHVEQYFDHPKLQQVMQYTLVFLGGSPDTTPALYNLMSHVDFGLGVYYPEGGMGGVVDGITALARELGVEFRTGHPVSAIKGRRGGFKLDTEPGDAVLADVVVSDADYAHTEQALLPAQKRQYDADYWDARTYAPSAFLLYLGVEGDVEPLAHHTLVLPSDWDTHFAQIFDDPAWPDDPAYYLCVPSKTDDTVAPDGHSNLFALVPVAPGLDDTPAVRESYRDLVLDDIAENTGVDLRDRIVVEERFSVSEFADRYNSHQGTALGLAHTLRQTALFRPPHRSTALDGLYFTGANTTPGIGVPMCLISGEVTANNVLADAR	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	512 (446)
Sequences:	14703 (11743)
Seq/√Len:	556.1

BACSU - PPOX YOBN
HALSA - Q9HPD8 Q9HP88 Q9HSE1 Q9HRU3 Q9HP54 Q9HRN2
SULSO - Q97W24 Q97UT6 Q97YW3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
8_S	31_D	4.355	1.00
10_A	291_A	4.113	1.00
33_T	264_R	3.800	1.00
256_A	261_V	3.793	1.00
8_S	292_D	3.648	1.00
37_K	268_P	3.645	1.00
41_I	265_T	3.463	1.00
271_A	282_D	3.384	1.00
21_T	295_V	3.297	1.00
84_G	242_E	3.198	1.00
35_V	289_V	3.158	1.00
296_S	303_T	2.943	1.00
10_A	35_V	2.914	1.00
41_I	253_T	2.906	1.00
39_D	266_G	2.840	1.00
10_A	289_V	2.774	1.00
409_V	412_S	2.752	1.00
14_A	41_I	2.707	1.00
500_G	504_A	2.654	1.00
273_K	282_D	2.649	1.00
282_D	288_A	2.633	1.00
10_A	281_L	2.603	1.00
246_G	250_D	2.600	1.00
31_D	262_E	2.577	1.00
267_H	283_T	2.534	1.00
273_K	280_K	2.516	1.00
270_S	284_E	2.496	1.00
12_I	296_S	2.434	1.00
268_P	284_E	2.417	1.00
247_G	250_D	2.398	1.00
35_V	264_R	2.321	1.00
283_T	289_V	2.312	1.00
443_E	446_D	2.245	1.00
253_T	257_R	2.229	1.00
422_A	430_R	2.211	1.00
297_D	483_T	2.204	1.00
24_Y	501_E	2.204	1.00
9_V	30_A	2.204	1.00
253_T	263_F	2.200	1.00
264_R	267_H	2.171	1.00
280_K	288_A	2.170	1.00
49_E	54_R	2.093	1.00
189_G	197_Q	2.063	1.00
16_F	493_V	2.048	1.00
8_S	33_T	2.045	1.00
293_V	481_Y	2.040	1.00
264_R	287_D	2.038	1.00
12_I	298_A	2.006	1.00
35_V	291_A	1.991	1.00
337_E	432_R	1.986	1.00
40_Q	46_S	1.977	1.00
28_A	508_L	1.963	1.00
192_Q	196_E	1.962	1.00
47_T	54_R	1.957	1.00
415_D	419_D	1.948	1.00
251_G	254_A	1.900	1.00
86_T	242_E	1.899	1.00
17_G	297_D	1.864	1.00
24_Y	27_D	1.856	1.00
20_S	497_L	1.854	1.00
295_V	507_V	1.842	1.00
280_K	290_L	1.841	1.00
130_K	145_D	1.833	1.00
270_S	282_D	1.819	1.00
23_C	255_L	1.815	1.00
7_T	33_T	1.799	1.00
449_N	453_G	1.779	1.00
24_Y	505_N	1.766	1.00
450_S	453_G	1.758	1.00
196_E	205_Q	1.751	1.00
264_R	289_V	1.736	1.00
390_H	434_V	1.728	1.00
30_A	508_L	1.715	1.00
337_E	434_V	1.710	1.00
9_V	293_V	1.700	1.00
27_D	74_S	1.696	1.00
422_A	428_D	1.695	1.00
411_E	415_D	1.687	1.00
190_S	193_D	1.675	1.00
146_D	150_Q	1.651	1.00
414_R	436_E	1.638	1.00
267_H	285_P	1.621	1.00
33_T	262_E	1.580	1.00
22_A	34_V	1.577	1.00
273_K	288_A	1.573	1.00
483_T	503_T	1.528	1.00
125_D	128_Q	1.526	1.00
298_A	303_T	1.520	1.00
272_I	279_F	1.520	1.00
271_A	309_P	1.515	1.00
35_V	269_V	1.500	1.00
73_A	78_H	1.494	1.00
41_I	249_V	1.494	1.00
337_E	390_H	1.487	1.00
269_V	281_L	1.480	1.00
45_A	249_V	1.460	1.00
338_G	432_R	1.446	1.00
443_E	447_R	1.445	1.00
279_F	294_V	1.435	1.00
453_G	456_L	1.427	1.00
14_A	34_V	1.422	1.00
53_F	335_G	1.420	1.00
70_E	501_E	1.417	1.00
256_A	263_F	1.416	1.00
250_D	254_A	1.412	1.00
23_C	27_D	1.408	1.00
11_V	22_A	1.402	1.00
33_T	291_A	1.400	1.00
254_A	257_R	1.394	1.00
245_M	493_V	1.392	1.00
8_S	30_A	1.389	1.00
70_E	74_S	1.388	1.00
69_E	73_A	1.382	1.00
313_R	316_D	1.380	1.00
34_V	263_F	1.378	1.00
10_A	33_T	1.377	1.00
348_L	351_P	1.372	1.00
18_G	297_D	1.361	1.00
283_T	287_D	1.357	1.00
142_D	146_D	1.354	1.00
33_T	289_V	1.352	1.00
293_V	507_V	1.348	1.00
41_I	263_F	1.339	1.00
279_F	479_G	1.339	1.00
257_R	262_E	1.336	1.00
9_V	25_L	1.322	1.00
17_G	499_S	1.304	1.00
432_R	435_V	1.300	1.00
415_D	430_R	1.296	1.00
143_V	146_D	1.289	1.00
267_H	287_D	1.287	1.00
481_Y	503_T	1.273	1.00
291_A	294_V	1.269	1.00
192_Q	220_D	1.261	1.00
336_V	418_L	1.251	1.00
26_A	261_V	1.247	1.00
147_Y	150_Q	1.246	1.00
44_R	485_A	1.240	1.00
442_S	445_A	1.227	1.00
127_E	130_K	1.221	1.00
67_V	501_E	1.217	1.00
503_T	506_N	1.216	1.00
334_L	418_L	1.206	1.00
408_A	412_S	1.201	1.00
123_T	128_Q	1.201	1.00
502_V	506_N	1.198	1.00
274_G	279_F	1.194	1.00
23_C	252_I	1.193	1.00
412_S	415_D	1.193	1.00
299_D	302_H	1.189	1.00
35_V	283_T	1.189	1.00
457_G	460_H	1.188	1.00
298_A	307_L	1.176	1.00
7_T	292_D	1.170	1.00
414_R	418_L	1.169	1.00
444_F	447_R	1.158	1.00
49_E	52_G	1.156	1.00
24_Y	74_S	1.156	1.00
257_R	260_G	1.145	1.00
250_D	253_T	1.143	1.00
50_R	437_E	1.143	1.00
302_H	306_A	1.137	1.00
300_Y	486_N	1.137	1.00
26_A	32_V	1.135	1.00
25_L	504_A	1.132	1.00
420_D	424_N	1.131	1.00
49_E	246_G	1.126	1.00
35_V	267_H	1.122	1.00
481_Y	507_V	1.120	1.00
11_V	32_V	1.111	1.00
267_H	289_V	1.110	1.00
428_D	431_D	1.110	1.00
477_L	480_L	1.110	1.00
418_L	422_A	1.105	1.00
372_A	377_V	1.102	1.00
272_I	294_V	1.098	1.00
347_T	351_P	1.098	1.00
123_T	132_V	1.098	1.00
177_K	181_Y	1.097	1.00
241_P	248_V	1.094	1.00
275_R	290_L	1.093	1.00
487_T	502_V	1.093	1.00
419_D	430_R	1.090	1.00
374_Y	378_P	1.089	1.00
189_G	193_D	1.088	1.00
17_G	483_T	1.084	1.00
180_E	183_R	1.082	1.00
48_L	57_M	1.078	1.00
396_L	399_V	1.069	1.00
416_L	419_D	1.063	1.00
278_G	290_L	1.059	1.00
453_G	458_L	1.054	1.00
317_A	321_D	1.054	1.00
243_G	247_G	1.045	1.00
220_D	223_P	1.044	1.00
414_R	417_V	1.040	1.00
481_Y	506_N	1.040	1.00
16_F	45_A	1.038	1.00
405_D	408_A	1.034	1.00
53_F	387_P	1.034	1.00
501_E	505_N	1.032	1.00
370_D	424_N	1.030	1.00
487_T	499_S	1.029	1.00
272_I	281_L	1.029	1.00
23_C	74_S	1.019	1.00
24_Y	500_G	1.008	1.00
247_G	251_G	1.002	1.00
433_I	436_E	1.001	1.00
100_E	203_K	1.000	1.00
457_G	461_T	0.997	1.00
253_T	265_T	0.997	1.00
466_A	469_R	0.995	1.00
440_S	443_E	0.995	1.00
274_G	479_G	0.994	1.00
26_A	256_A	0.993	1.00
293_V	479_G	0.987	1.00
461_T	464_Q	0.987	1.00
318_D	321_D	0.986	1.00
7_T	31_D	0.983	1.00
24_Y	28_A	0.982	1.00
371_P	377_V	0.981	1.00
201_H	205_Q	0.980	1.00
181_Y	184_G	0.979	1.00
146_D	149_A	0.977	1.00
372_A	375_L	0.977	1.00
8_S	289_V	0.972	1.00
458_L	461_T	0.968	1.00
152_K	156_E	0.967	1.00
23_C	256_A	0.964	1.00
14_A	265_T	0.960	1.00
309_P	312_K	0.960	1.00
149_A	153_E	0.957	1.00
128_Q	131_Q	0.957	1.00
153_E	156_E	0.956	1.00
456_L	460_H	0.955	1.00
255_L	258_E	0.951	1.00
397_V	417_V	0.950	1.00
374_Y	377_V	0.948	1.00
84_G	87_R	0.946	1.00
70_E	73_A	0.945	1.00
228_L	232_V	0.942	1.00
377_V	380_K	0.938	1.00
196_E	201_H	0.934	1.00
257_R	261_V	0.933	1.00
202_P	206_Q	0.932	1.00
442_S	446_D	0.930	1.00
484_G	499_S	0.930	1.00
156_E	159_M	0.930	1.00
394_F	398_P	0.929	1.00
144_L	147_Y	0.929	1.00
95_F	100_E	0.928	1.00
30_A	33_T	0.928	1.00
67_V	70_E	0.923	1.00
182_A	185_L	0.921	1.00
131_Q	134_D	0.921	1.00
347_T	350_L	0.920	1.00
412_S	416_L	0.916	1.00
226_Y	229_M	0.915	1.00
142_D	147_Y	0.910	1.00
97_K	100_E	0.909	1.00
269_V	283_T	0.908	1.00
309_P	313_R	0.908	1.00
169_R	172_D	0.906	1.00
272_I	296_S	0.905	1.00
47_T	246_G	0.901	1.00
296_S	480_L	0.899	1.00
217_G	223_P	0.898	1.00
346_H	351_P	0.897	1.00
194_H	198_Y	0.897	1.00
270_S	283_T	0.897	1.00
228_L	234_F	0.893	1.00
241_P	247_G	0.888	1.00
347_T	352_S	0.886	1.00
93_R	121_D	0.886	1.00
219_P	222_T	0.883	1.00
149_A	152_K	0.883	1.00
414_R	438_R	0.883	1.00
336_V	433_I	0.883	1.00
459_A	464_Q	0.881	1.00
346_H	350_L	0.876	1.00
230_S	234_F	0.876	1.00
38_T	46_S	0.873	1.00
318_D	322_A	0.871	1.00
332_L	438_R	0.867	1.00
226_Y	230_S	0.867	1.00
275_R	278_G	0.867	1.00
8_S	290_L	0.865	1.00
20_S	500_G	0.861	1.00
273_K	310_A	0.860	1.00
231_H	234_F	0.859	1.00
373_Y	376_C	0.858	1.00
218_S	221_T	0.857	1.00
346_H	349_V	0.855	1.00
465_T	469_R	0.853	1.00
456_L	459_A	0.851	1.00
373_Y	378_P	0.850	1.00
268_P	306_A	0.849	1.00
143_V	147_Y	0.849	1.00
29_G	32_V	0.849	1.00
249_V	253_T	0.846	1.00
7_T	10_A	0.846	1.00
72_F	77_S	0.842	1.00
75_F	252_I	0.842	1.00
410_R	440_S	0.842	1.00
419_D	424_N	0.839	1.00
254_A	258_E	0.838	1.00
271_A	310_A	0.838	1.00
96_F	99_N	0.836	1.00
283_T	286_G	0.835	1.00
17_G	496_C	0.835	1.00
453_G	459_A	0.834	1.00
145_D	150_Q	0.832	1.00
419_D	422_A	0.830	1.00
21_T	500_G	0.830	1.00
153_E	157_V	0.829	1.00
145_D	149_A	0.829	1.00
371_P	374_Y	0.827	1.00
142_D	145_D	0.827	1.00
77_S	258_E	0.824	1.00
280_K	283_T	0.823	1.00
128_Q	132_V	0.818	1.00
20_S	252_I	0.816	1.00
371_P	378_P	0.812	1.00
373_Y	377_V	0.809	1.00
205_Q	209_Q	0.804	1.00
152_K	155_Y	0.804	1.00
53_F	390_H	0.803	1.00
71_F	75_F	0.803	1.00
235_G	239_Y	0.801	1.00
415_D	436_E	0.800	1.00
53_F	434_V	0.799	1.00
130_K	134_D	0.797	1.00
449_N	452_Q	0.794	1.00
334_L	395_A	0.793	1.00
453_G	460_H	0.793	1.00
226_Y	231_H	0.792	1.00
474_S	506_N	0.792	1.00
140_A	143_V	0.792	1.00
218_S	223_P	0.791	1.00
335_G	435_V	0.791	1.00
217_G	222_T	0.790	1.00
496_C	500_G	0.789	1.00
73_A	76_D	0.788	1.00
31_D	292_D	0.787	1.00
141_G	145_D	0.782	1.00
411_E	414_R	0.781	1.00
155_Y	158_G	0.780	1.00
33_T	292_D	0.778	1.00
34_V	256_A	0.778	1.00
36_E	265_T	0.778	1.00
394_F	397_V	0.775	1.00
144_L	150_Q	0.774	1.00
178_L	181_Y	0.774	1.00
68_F	497_L	0.772	1.00
143_V	150_Q	0.771	1.00
467_L	470_P	0.769	1.00
270_S	273_K	0.767	1.00
391_S	394_F	0.767	1.00
44_R	58_G	0.766	1.00
27_D	255_L	0.764	1.00
22_A	256_A	0.763	1.00
129_V	132_V	0.763	1.00
85_L	88_L	0.762	1.00
347_T	353_D	0.761	1.00
134_D	139_G	0.761	1.00
227_N	230_S	0.761	1.00
145_D	148_L	0.758	1.00
351_P	354_W	0.757	1.00
335_G	434_V	0.756	1.00
201_H	204_L	0.755	1.00
19_L	34_V	0.755	1.00
19_L	256_A	0.754	1.00
11_V	18_G	0.754	1.00
157_V	160_E	0.754	1.00
278_G	478_D	0.753	1.00
180_E	184_G	0.751	1.00
30_A	292_D	0.749	1.00
345_H	351_P	0.747	1.00
171_R	174_M	0.747	1.00
455_A	459_A	0.746	1.00
372_A	378_P	0.745	1.00
16_F	496_C	0.743	1.00
8_S	291_A	0.739	1.00
295_V	481_Y	0.738	1.00
179_A	182_A	0.737	1.00
20_S	24_Y	0.737	1.00
45_A	59_P	0.736	1.00
498_I	502_V	0.734	1.00
420_D	425_T	0.733	1.00
189_G	194_H	0.732	1.00
275_R	280_K	0.729	1.00
444_F	449_N	0.728	1.00
72_F	241_P	0.727	1.00
504_A	507_V	0.725	1.00
349_V	352_S	0.723	1.00
56_D	245_M	0.723	1.00
223_P	227_N	0.722	1.00
28_A	505_N	0.722	1.00
16_F	249_V	0.721	1.00
26_A	262_E	0.720	1.00
23_C	75_F	0.720	1.00
503_T	507_V	0.715	1.00
148_L	152_K	0.712	1.00
16_F	497_L	0.711	1.00
410_R	414_R	0.709	1.00
147_Y	151_A	0.709	1.00
181_Y	185_L	0.708	1.00
199_F	208_M	0.707	1.00
35_V	281_L	0.706	1.00
230_S	233_D	0.705	1.00
294_V	479_G	0.704	1.00
144_L	149_A	0.702	1.00
421_I	429_L	0.702	1.00
371_P	375_L	0.702	1.00
298_A	302_H	0.702	1.00
382_D	385_V	0.701	1.00
10_A	294_V	0.700	1.00
178_L	182_A	0.699	1.00
451_H	454_T	0.699	1.00
168_P	172_D	0.699	1.00
274_G	477_L	0.698	1.00
251_G	255_L	0.694	1.00
96_F	100_E	0.693	1.00
200_D	204_L	0.693	1.00
441_V	444_F	0.692	1.00
177_K	180_E	0.689	1.00
202_P	205_Q	0.689	1.00
422_A	431_D	0.688	1.00
150_Q	153_E	0.688	1.00
222_T	227_N	0.687	1.00
335_G	390_H	0.686	1.00
169_R	174_M	0.686	1.00
127_E	131_Q	0.685	1.00
300_Y	304_E	0.685	1.00
192_Q	209_Q	0.678	1.00
170_V	174_M	0.678	1.00
460_H	463_R	0.676	1.00
217_G	221_T	0.676	1.00
12_I	269_V	0.676	1.00
227_N	231_H	0.675	1.00
336_V	340_V	0.673	1.00
134_D	141_G	0.671	1.00
483_T	500_G	0.670	1.00
150_Q	154_N	0.668	1.00
40_Q	246_G	0.667	1.00
220_D	224_A	0.667	1.00
7_T	30_A	0.666	1.00
418_L	436_E	0.664	1.00
21_T	503_T	0.663	1.00
122_V	125_D	0.661	1.00
209_Q	219_P	0.660	1.00
464_Q	469_R	0.658	1.00
50_R	435_V	0.658	1.00
320_W	323_R	0.657	1.00
125_D	129_V	0.656	1.00
16_F	252_I	0.655	1.00
235_G	238_V	0.653	1.00
415_D	418_L	0.653	1.00
179_A	183_R	0.652	1.00
16_F	20_S	0.652	1.00
93_R	97_K	0.652	1.00
392_N	396_L	0.652	1.00
83_Y	86_T	0.651	1.00
169_R	173_W	0.651	1.00
22_A	261_V	0.650	1.00
270_S	285_P	0.647	1.00
67_V	498_I	0.645	1.00
45_A	493_V	0.644	1.00
463_R	466_A	0.644	1.00
30_A	293_V	0.642	1.00
452_Q	455_A	0.642	1.00
330_F	438_R	0.639	1.00
20_S	71_F	0.638	1.00
122_V	129_V	0.638	1.00
453_G	457_G	0.638	1.00
86_T	89_D	0.637	1.00
227_N	232_V	0.637	1.00
300_Y	320_W	0.636	1.00
67_V	497_L	0.635	1.00
371_P	376_C	0.632	1.00
387_P	390_H	0.631	1.00
121_D	124_P	0.630	1.00
295_V	503_T	0.629	1.00
119_T	122_V	0.628	1.00
226_Y	233_D	0.627	1.00
428_D	432_R	0.626	1.00
120_I	125_D	0.626	1.00
229_M	232_V	0.625	1.00
395_A	421_I	0.625	1.00
193_D	196_E	0.625	1.00
59_P	493_V	0.623	1.00
452_Q	456_L	0.623	1.00
34_V	41_I	0.623	1.00
217_G	220_D	0.623	1.00
375_L	378_P	0.623	1.00
296_S	482_F	0.622	1.00
299_D	486_N	0.620	1.00
170_V	173_W	0.620	1.00
146_D	152_K	0.618	1.00
56_D	61_W	0.618	1.00
11_V	295_V	0.617	1.00
206_Q	210_Y	0.617	1.00
152_K	157_V	0.617	1.00
72_F	75_F	0.617	1.00
236_L	239_Y	0.616	1.00
274_G	277_G	0.615	1.00
436_E	439_F	0.615	1.00
195_V	205_Q	0.614	1.00
349_V	353_D	0.613	1.00
59_P	245_M	0.611	1.00
442_S	447_R	0.610	1.00
177_K	183_R	0.610	1.00
345_H	348_L	0.608	1.00
431_D	434_V	0.607	1.00
502_V	505_N	0.607	1.00
348_L	353_D	0.607	1.00
68_F	494_P	0.606	1.00
299_D	451_H	0.606	1.00
418_L	430_R	0.605	1.00
227_N	233_D	0.605	1.00
336_V	341_E	0.601	1.00
278_G	292_D	0.601	1.00
346_H	352_S	0.601	1.00
71_F	74_S	0.599	1.00
191_M	227_N	0.598	1.00
123_T	130_K	0.598	1.00
455_A	458_L	0.598	1.00
416_L	420_D	0.597	1.00
228_L	231_H	0.596	1.00
281_L	294_V	0.596	1.00
504_A	508_L	0.595	1.00
226_Y	234_F	0.595	1.00
60_S	394_F	0.594	1.00
439_F	443_E	0.593	1.00
244_G	247_G	0.593	1.00
371_P	420_D	0.589	1.00
195_V	209_Q	0.589	1.00
121_D	125_D	0.586	1.00
386_A	390_H	0.586	1.00
143_V	151_A	0.586	1.00
394_F	399_V	0.585	1.00
214_F	217_G	0.585	1.00
464_Q	468_F	0.584	1.00
178_L	185_L	0.584	1.00
345_H	349_V	0.583	1.00
93_R	100_E	0.583	1.00
454_T	459_A	0.583	1.00
216_G	224_A	0.582	1.00
346_H	353_D	0.582	1.00
345_H	350_L	0.580	1.00
227_N	234_F	0.580	1.00
47_T	244_G	0.578	0.99
493_V	497_L	0.577	0.99
370_D	420_D	0.575	0.99
489_P	492_G	0.573	0.99
55_F	333_Y	0.573	0.99
48_L	437_E	0.572	0.99
278_G	479_G	0.569	0.99
147_Y	155_Y	0.568	0.99
214_F	219_P	0.567	0.99
120_I	123_T	0.567	0.99
145_D	152_K	0.566	0.99
47_T	56_D	0.566	0.99
45_A	245_M	0.565	0.99
70_E	76_D	0.564	0.99
229_M	233_D	0.563	0.99
191_M	195_V	0.563	0.99
455_A	460_H	0.563	0.99
430_R	433_I	0.562	0.99
418_L	433_I	0.561	0.99
346_H	354_W	0.561	0.99
143_V	148_L	0.560	0.99
120_I	124_P	0.560	0.99
293_V	296_S	0.557	0.99
295_V	483_T	0.557	0.99
390_H	394_F	0.556	0.99
393_L	397_V	0.556	0.99
348_L	352_S	0.555	0.99
205_Q	210_Y	0.554	0.99
334_L	414_R	0.552	0.99
451_H	456_L	0.552	0.99
449_N	455_A	0.552	0.99
174_M	177_K	0.552	0.99
441_V	446_D	0.551	0.99
56_D	59_P	0.549	0.99
393_L	398_P	0.549	0.99
402_G	405_D	0.548	0.99
410_R	413_Y	0.548	0.99
395_A	399_V	0.548	0.99
55_F	392_N	0.547	0.99
224_A	227_N	0.545	0.99
194_H	224_A	0.545	0.99
451_H	455_A	0.544	0.99
11_V	34_V	0.543	0.99
250_D	257_R	0.543	0.99
411_E	436_E	0.543	0.99
465_T	468_F	0.543	0.99
129_V	133_F	0.542	0.99
121_D	128_Q	0.542	0.99
281_L	284_E	0.541	0.99
466_A	470_P	0.540	0.99
154_N	157_V	0.539	0.99
253_T	261_V	0.538	0.99
374_Y	379_S	0.537	0.99
247_G	254_A	0.537	0.99
465_T	470_P	0.537	0.99
379_S	391_S	0.536	0.99
450_S	454_T	0.536	0.99
473_R	476_A	0.536	0.99
213_V	217_G	0.533	0.99
370_D	377_V	0.533	0.99
70_E	75_F	0.531	0.99
14_A	253_T	0.531	0.99
475_T	478_D	0.530	0.99
475_T	482_F	0.530	0.99
88_L	91_H	0.528	0.99
9_V	507_V	0.528	0.99
450_S	456_L	0.528	0.99
59_P	63_L	0.527	0.99
67_V	71_F	0.527	0.99
93_R	96_F	0.527	0.99
69_E	72_F	0.526	0.99
301_A	325_Y	0.525	0.99
406_T	410_R	0.523	0.99
371_P	379_S	0.522	0.99
72_F	76_D	0.522	0.99
87_R	90_P	0.522	0.99
85_L	89_D	0.522	0.99
39_D	265_T	0.522	0.99
126_R	130_K	0.522	0.99
127_E	145_D	0.520	0.99
50_R	335_G	0.520	0.99
413_Y	416_L	0.519	0.99
262_E	265_T	0.519	0.99
306_A	309_P	0.518	0.99
208_M	211_T	0.518	0.99
178_L	183_R	0.517	0.99
14_A	19_L	0.517	0.99
488_T	502_V	0.516	0.99
330_F	397_V	0.516	0.99
121_D	130_K	0.516	0.99
150_Q	198_Y	0.515	0.99
68_F	72_F	0.513	0.99
313_R	317_A	0.512	0.99
142_D	149_A	0.512	0.99
26_A	257_R	0.512	0.99
408_A	413_Y	0.512	0.99
391_S	398_P	0.511	0.99
431_D	435_V	0.511	0.99
451_H	458_L	0.511	0.99
344_A	349_V	0.511	0.99
215_L	227_N	0.509	0.99
240_Y	245_M	0.507	0.99
19_L	249_V	0.507	0.99
67_V	494_P	0.507	0.99
168_P	171_R	0.506	0.99
241_P	245_M	0.506	0.99
51_D	435_V	0.504	0.99
348_L	354_W	0.504	0.99
216_G	219_P	0.503	0.99
220_D	225_L	0.503	0.99
435_V	438_R	0.503	0.99
195_V	199_F	0.503	0.99
124_P	127_E	0.503	0.99
146_D	154_N	0.502	0.99
338_G	391_S	0.502	0.99
24_Y	71_F	0.501	0.99
271_A	308_L	0.501	0.99
336_V	393_L	0.500	0.99

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4dgkA	1	0.7793	100	0.337	Contact Map
4repA	1	0.9414	100	0.373	Contact Map
4i59A	1	0.8379	100	0.413	Contact Map
2yg5A	2	0.8418	100	0.416	Contact Map
1s3eA	2	0.8477	100	0.439	Contact Map
2ivdA	1	0.8164	100	0.446	Contact Map
3i6dA	1	0.7988	100	0.449	Contact Map
1sezA	3	0.8242	100	0.457	Contact Map
2vvmA	2	0.8398	100	0.461	Contact Map
1b37A	4	0.8281	100	0.465	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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