GREMLIN Database
RL24 - 50S ribosomal protein L24P
UniProt: Q9HPC3 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 118 (114)
Sequences: 478 (280)
Seq/√Len: 26.2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
73_V97_L6.9261.00
52_M98_R3.4061.00
33_R39_R2.6110.99
38_Q113_L2.4990.99
23_Q71_A2.3120.98
2_S8_Q2.1910.97
112_R115_G2.1700.97
27_T97_L2.1260.97
41_V99_V2.0760.96
16_S19_E1.8450.93
63_V73_V1.8430.93
78_V90_R1.7630.91
27_T52_M1.7330.91
24_V42_R1.6930.90
74_F91_P1.6860.89
17_L21_Q1.6170.87
75_V78_V1.6160.87
5_P12_T1.5950.87
53_R58_G1.5620.85
5_P9_R1.5340.84
21_Q68_L1.5160.84
33_R58_G1.4620.81
51_V78_V1.4290.80
28_L32_L1.4020.78
37_G113_L1.4000.78
22_D116_D1.3900.78
41_V113_L1.3000.73
19_E22_D1.2950.73
82_A85_G1.2870.72
22_D69_R1.2760.71
43_V73_V1.2300.69
79_T89_P1.2280.68
38_Q41_V1.2190.68
24_V68_L1.2180.68
64_T74_F1.2120.67
43_V71_A1.2000.67
5_P13_K1.1990.67
41_V102_L1.1930.66
37_G45_V1.1910.66
51_V75_V1.1850.66
84_D103_D1.1750.65
55_D59_E1.1730.65
110_V116_D1.1570.64
56_D59_E1.1450.63
19_E58_G1.1390.63
104_L113_L1.1380.62
42_R71_A1.1320.62
14_R114_E1.1180.61
26_A101_D1.1060.60
50_E98_R1.1000.60
35_E38_Q1.0970.60
30_E43_V1.0850.59
56_D90_R1.0640.57
39_R96_N1.0600.57
36_Y113_L1.0470.56
62_E76_E1.0370.55
27_T96_N1.0260.54
12_T23_Q1.0180.54
70_D107_D1.0070.53
17_L68_L1.0050.53
20_K109_R1.0040.53
61_G75_V1.0010.53
30_E99_V0.9950.52
60_D100_T0.9830.51
79_T110_V0.9740.51
47_D109_R0.9680.50
62_E107_D0.9650.50
42_R113_L0.9610.50
70_D82_A0.9500.49
51_V92_V0.9410.48
67_D70_D0.9380.48
45_V73_V0.9300.47
54_G66_V0.9250.47
80_V90_R0.9140.46
25_R40_N0.9090.46
30_E35_E0.9090.46
54_G61_G0.9060.46
38_Q99_V0.8970.45
9_R20_K0.8810.44
72_E93_E0.8710.43
48_T100_T0.8650.43
25_R42_R0.8460.41
2_S101_D0.8380.41
50_E58_G0.8290.40
24_V71_A0.8210.39
58_G112_R0.8150.39
24_V73_V0.8060.38
2_S63_V0.8050.38
47_D63_V0.7990.38
43_V63_V0.7880.37
5_P14_R0.7860.37
9_R109_R0.7820.37
35_E107_D0.7740.36
42_R68_L0.7600.35
33_R89_P0.7470.34
30_E82_A0.7450.34
60_D111_E0.7440.34
29_S90_R0.7430.34
64_T89_P0.7420.34
104_L108_M0.7420.34
10_T99_V0.7410.34
33_R40_N0.7350.33
11_R49_V0.7330.33
36_Y100_T0.7320.33
42_R112_R0.7250.33
25_R39_R0.7140.32
26_A97_L0.7080.32
25_R105_D0.7070.32
55_D90_R0.7020.31
27_T39_R0.7010.31
76_E81_E0.6990.31
51_V56_D0.6970.31
46_G67_D0.6960.31
99_V115_G0.6930.31
65_D96_N0.6880.30
30_E56_D0.6880.30
61_G109_R0.6860.30
41_V90_R0.6820.30
8_Q69_R0.6780.30
36_Y76_E0.6750.30
104_L110_V0.6740.30
30_E83_A0.6720.29
4_Q68_L0.6700.29
83_A96_N0.6660.29
42_R57_A0.6600.29
48_T84_D0.6580.29
8_Q18_H0.6480.28
53_R96_N0.6450.28
2_S76_E0.6410.28
44_N115_G0.6370.27
24_V66_V0.6360.27
5_P8_Q0.6340.27
49_V76_E0.6310.27
16_S20_K0.6270.27
40_N105_D0.6250.27
4_Q91_P0.6230.26
51_V90_R0.6230.26
103_D114_E0.6180.26
32_L39_R0.6160.26
41_V112_R0.6080.26
24_V28_L0.6050.25
39_R113_L0.5990.25
22_D66_V0.5980.25
9_R53_R0.5980.25
110_V114_E0.5940.25
31_E34_E0.5880.25
24_V94_S0.5870.24
51_V96_N0.5840.24
38_Q116_D0.5720.24
27_T101_D0.5650.23
97_L103_D0.5640.23
90_R113_L0.5570.23
48_T101_D0.5540.23
54_G109_R0.5540.23
46_G87_E0.5520.23
59_E78_V0.5520.23
67_D91_P0.5460.22
29_S98_R0.5430.22
38_Q42_R0.5360.22
2_S45_V0.5300.21
26_A45_V0.5300.21
44_N113_L0.5260.21
50_E77_G0.5250.21
40_N71_A0.5200.21
48_T68_L0.5170.21
51_V114_E0.5170.21
60_D78_V0.5120.21
53_R109_R0.5100.20
12_T72_E0.5080.20
42_R94_S0.5010.20
14_R18_H0.5000.20
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3j61Y 1 0.9915 100 0.233 Contact Map
4ujrL 1 0.9915 100 0.241 Contact Map
3zf7Z 1 0.9915 100 0.241 Contact Map
1vx7Z 1 0.9831 100 0.242 Contact Map
1vq8T 1 0.9915 100 0.243 Contact Map
4w20Y 1 0.9915 100 0.245 Contact Map
4a17S 1 0.9915 100 0.248 Contact Map
3j21U 1 1 100 0.261 Contact Map
3j7yV 1 0.9068 99.9 0.495 Contact Map
3bboW 1 0.6441 99.9 0.52 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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