GREMLIN Database
RL19E - 50S ribosomal protein L19e
UniProt: Q9HPB6 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 149 (142)
Sequences: 392 (238)
Seq/√Len: 20.0

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
24_F32_I5.7611.00
99_I127_A5.1911.00
60_R64_R4.1241.00
86_G91_E3.6961.00
8_K19_E3.0260.99
123_M141_Y2.9470.99
28_A49_T2.4420.97
60_R63_A2.3460.96
39_E42_R2.3060.96
14_V45_V2.2860.95
59_S62_R2.2680.95
93_R96_V2.2380.95
69_K75_K2.2210.95
4_L38_R2.1610.94
116_S119_Q2.0430.92
88_R103_R1.9320.89
69_K74_H1.8990.88
15_L52_A1.8670.87
105_Q139_T1.8540.87
6_A10_L1.8200.86
73_G132_F1.7240.83
38_R103_R1.6420.80
32_I44_L1.6370.79
61_G65_E1.5830.77
126_M131_E1.5780.77
22_V45_V1.5560.76
133_D137_R1.5120.74
3_D6_A1.4850.72
23_W51_D1.4780.72
99_I121_R1.4170.69
22_V97_A1.3910.67
102_Q138_L1.3900.67
65_E69_K1.3710.66
47_D51_D1.3620.65
35_A111_D1.3520.65
15_L45_V1.3460.64
9_R13_D1.3010.62
8_K78_A1.2790.60
108_E114_T1.2790.60
7_Q110_R1.2650.60
21_R55_T1.2400.58
126_M134_S1.2380.58
7_Q32_I1.2080.56
85_A113_G1.2070.56
42_R62_R1.1960.55
10_L14_V1.1840.54
50_I106_L1.1510.52
110_R127_A1.1090.50
15_L77_G1.1020.49
30_S37_T1.0840.48
88_R129_G1.0790.48
57_G113_G1.0670.47
77_G103_R1.0570.46
94_E98_G1.0530.46
34_D141_Y1.0310.44
56_Q122_E1.0290.44
79_G83_G1.0280.44
89_Q94_E1.0250.44
80_S91_E1.0110.43
81_R110_R1.0030.43
69_K72_Y1.0010.43
17_V123_M0.9920.42
31_E82_K0.9920.42
116_S123_M0.9680.40
102_Q142_V0.9610.40
39_E109_L0.9590.40
38_R110_R0.9460.39
102_Q135_V0.9440.39
34_D40_D0.9290.38
135_V143_E0.9210.38
14_V32_I0.9100.37
9_R18_G0.9010.36
122_E126_M0.9000.36
23_W77_G0.8900.36
8_K38_R0.8880.36
7_Q35_A0.8850.35
25_D69_K0.8840.35
10_L116_S0.8830.35
109_L142_V0.8770.35
83_G103_R0.8770.35
67_D107_R0.8750.35
76_K86_G0.8720.35
136_R139_T0.8690.34
31_E46_A0.8680.34
36_I74_H0.8650.34
80_S137_R0.8640.34
15_L66_R0.8570.34
17_V97_A0.8490.33
26_P123_M0.8490.33
3_D16_D0.8450.33
135_V139_T0.8370.33
17_V22_V0.8360.33
105_Q108_E0.8350.33
11_A18_G0.8330.32
22_V52_A0.8320.32
95_Y110_R0.8240.32
99_I139_T0.8170.32
13_D118_A0.8080.31
46_A92_K0.8030.31
10_L105_Q0.8010.31
17_V52_A0.8000.31
123_M132_F0.7920.30
101_A108_E0.7920.30
84_K115_L0.7900.30
108_E139_T0.7860.30
37_T115_L0.7840.30
43_E47_D0.7720.29
28_A47_D0.7700.29
27_D123_M0.7690.29
19_E122_E0.7610.28
113_G117_P0.7610.28
44_L49_T0.7570.28
28_A31_E0.7520.28
90_N97_A0.7520.28
11_A81_R0.7510.28
42_R48_G0.7490.28
4_L16_D0.7490.28
128_N133_D0.7410.27
114_T133_D0.7400.27
4_L98_G0.7330.27
74_H110_R0.7320.27
24_F99_I0.7310.27
26_P132_F0.7260.27
57_G76_K0.7240.27
63_A67_D0.7220.26
12_A56_Q0.7220.26
101_A135_V0.7170.26
7_Q120_Y0.7150.26
43_E112_D0.7150.26
37_T109_L0.7140.26
68_A72_Y0.7130.26
23_W26_P0.7130.26
94_E123_M0.7090.26
39_E122_E0.7080.26
139_T144_E0.7000.25
25_D28_A0.6980.25
41_I126_M0.6950.25
23_W129_G0.6950.25
17_V34_D0.6950.25
64_R70_E0.6940.25
92_K134_S0.6920.25
47_D138_L0.6900.25
20_N63_A0.6900.25
102_Q114_T0.6860.25
21_R144_E0.6860.25
110_R124_Y0.6850.25
42_R103_R0.6790.24
59_S100_R0.6760.24
137_R143_E0.6740.24
95_Y128_N0.6720.24
90_N96_V0.6680.24
60_R88_R0.6680.24
10_L98_G0.6660.24
114_T142_V0.6640.24
4_L33_A0.6560.23
105_Q135_V0.6530.23
38_R62_R0.6470.23
21_R51_D0.6420.23
74_H138_L0.6390.22
104_Q135_V0.6320.22
7_Q41_I0.6300.22
53_E114_T0.6270.22
76_K99_I0.6210.22
42_R133_D0.6150.21
3_D127_A0.6120.21
20_N66_R0.6040.21
60_R103_R0.6040.21
39_E56_Q0.5920.20
41_I143_E0.5900.20
6_A126_M0.5880.20
50_I134_S0.5750.20
16_D113_G0.5750.20
3_D102_Q0.5740.20
46_A55_T0.5720.20
44_L104_Q0.5700.20
125_N137_R0.5690.19
10_L96_V0.5680.19
77_G88_R0.5680.19
8_K91_E0.5660.19
10_L52_A0.5630.19
27_D130_G0.5610.19
39_E55_T0.5560.19
48_G120_Y0.5540.19
72_Y125_N0.5540.19
96_V110_R0.5520.19
24_F29_Q0.5520.19
87_A92_K0.5510.19
4_L7_Q0.5500.19
69_K98_G0.5440.18
68_A112_D0.5410.18
26_P48_G0.5410.18
71_S93_R0.5380.18
60_R106_L0.5360.18
3_D85_A0.5350.18
65_E72_Y0.5350.18
85_A122_E0.5310.18
4_L14_V0.5300.18
43_E58_N0.5260.18
34_D37_T0.5250.18
25_D74_H0.5250.18
56_Q85_A0.5220.18
123_M131_E0.5190.18
24_F43_E0.5180.17
15_L73_G0.5180.17
19_E32_I0.5170.17
57_G65_E0.5170.17
47_D53_E0.5160.17
35_A87_A0.5090.17
23_W28_A0.5080.17
70_E108_E0.5080.17
14_V113_G0.5030.17
20_N90_N0.5020.17
13_D112_D0.5000.17
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3zf7T 1 0.9933 100 -0.007 Contact Map
3j61R 1 1 100 -0.005 Contact Map
4a17O 1 0.9799 100 -0.001 Contact Map
4w20R 1 0.9933 100 -0.001 Contact Map
4a1aO 1 0.9933 100 -0 Contact Map
1vx7T 1 0.9866 100 0.012 Contact Map
4ujrE 1 0.9933 100 0.013 Contact Map
1vq8P 1 0.9597 100 0.016 Contact Map
3j21Q 1 1 100 0.017 Contact Map
3jywP 1 0.9933 100 0.108 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0059 seconds.