GREMLIN Database
RS5 - 30S ribosomal protein S5
UniProt: Q9HPB4 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 212 (161)
Sequences: 927 (460)
Seq/√Len: 36.3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
49_D79_R5.2151.00
190_N194_E3.6841.00
78_N82_Y3.4881.00
147_P171_W3.2281.00
53_L185_A2.9891.00
113_R167_I2.7601.00
61_M68_V2.6491.00
196_S204_A2.6371.00
70_F93_V2.5931.00
158_V172_T2.5041.00
128_V195_T2.4811.00
134_G190_N2.4261.00
61_M66_R2.3581.00
131_K145_P2.2370.99
41_V48_L2.1990.99
101_I105_K2.1930.99
61_M64_S2.1910.99
190_N193_R2.1910.99
162_L170_V2.1770.99
85_Y185_A2.0970.99
52_V55_I2.0910.99
74_V100_A1.9980.98
148_R169_D1.9840.98
126_H169_D1.9790.98
146_A150_L1.9780.98
128_V170_V1.9200.98
87_E182_V1.9010.98
127_T169_D1.8740.98
129_A195_T1.8340.97
41_V46_P1.7140.96
85_Y186_K1.6810.95
132_S194_E1.6440.95
182_V186_K1.6140.94
103_V107_N1.5620.93
131_K144_M1.5610.93
75_A161_V1.4520.90
48_L82_Y1.4160.89
157_T184_F1.3840.88
107_N172_T1.3810.88
132_S195_T1.3640.87
49_D164_L1.3580.87
83_V165_A1.3520.87
86_A103_V1.3480.87
69_K171_W1.3390.86
135_K140_D1.3100.85
82_Y108_I1.2960.84
60_R150_L1.2650.83
50_D55_I1.2370.81
81_G113_R1.2150.80
71_R87_E1.2000.79
95_G98_Q1.1980.79
157_T185_A1.1960.79
88_G99_K1.1890.79
169_D189_F1.1670.77
134_G201_P1.1550.77
89_R99_K1.1510.76
100_A166_G1.1380.76
90_D96_A1.1170.74
132_S143_L1.1050.73
67_R91_D1.1020.73
37_E44_L1.0970.73
128_V143_L1.0600.70
58_V189_F1.0520.70
37_E126_H1.0440.69
125_P206_E1.0430.69
141_V153_A1.0270.68
83_V98_Q1.0260.68
88_G96_A1.0100.66
150_L171_W1.0070.66
40_I48_L1.0040.66
111_V164_L1.0030.66
52_V74_V1.0010.66
51_E164_L0.9980.66
154_G172_T0.9940.65
56_N71_R0.9940.65
150_L155_G0.9900.65
197_E200_V0.9860.65
174_S184_F0.9730.64
140_D177_K0.9660.63
92_Q127_T0.9550.62
201_P204_A0.9530.62
80_D200_V0.9480.61
58_V69_K0.9410.61
139_V174_S0.9330.60
48_L80_D0.9290.60
69_K87_E0.9240.59
75_A160_H0.9220.59
41_V82_Y0.9070.58
79_R163_E0.9060.58
141_V187_A0.9050.58
151_G166_G0.8970.57
110_D169_D0.8940.57
143_L172_T0.8820.56
51_E141_V0.8730.55
152_L162_L0.8610.54
52_V97_I0.8570.54
170_V195_T0.8560.54
146_A176_G0.8530.53
161_V188_T0.8390.52
134_G139_V0.8370.52
53_L144_M0.8320.52
69_K90_D0.8260.51
75_A164_L0.8230.51
56_N181_T0.8210.51
40_I110_D0.8180.50
54_D71_R0.8160.50
52_V101_I0.8120.50
133_T142_E0.8070.49
76_I149_G0.8050.49
74_V101_I0.7930.48
76_I81_G0.7920.48
196_S200_V0.7900.48
126_H168_D0.7850.47
109_I193_R0.7820.47
168_D197_E0.7800.47
142_E147_P0.7790.47
129_A198_A0.7740.46
78_N110_D0.7740.46
105_K126_H0.7640.46
69_K91_D0.7560.45
143_L188_T0.7540.45
57_M64_S0.7520.45
80_D113_R0.7480.44
43_Q46_P0.7470.44
136_A186_K0.7450.44
65_G77_G0.7440.44
200_V203_H0.7410.44
89_R155_G0.7360.43
90_D103_V0.7350.43
42_D206_E0.7320.43
56_N132_S0.7180.42
73_V157_T0.7160.42
174_S179_R0.7150.41
68_V71_R0.7140.41
154_G173_R0.7120.41
100_A176_G0.7100.41
60_R64_S0.7090.41
190_N206_E0.7090.41
69_K82_Y0.7080.41
57_M61_M0.7080.41
57_M68_V0.7070.41
163_E177_K0.7060.41
74_V96_A0.7040.40
177_K184_F0.7000.40
114_G126_H0.6960.40
136_A180_T0.6940.40
114_G198_A0.6940.40
62_T67_R0.6910.39
143_L170_V0.6850.39
113_R126_H0.6800.38
189_F193_R0.6790.38
77_G84_G0.6730.38
109_I189_F0.6730.38
71_R85_Y0.6690.38
60_R153_A0.6680.38
47_G80_D0.6670.37
52_V164_L0.6640.37
51_E181_T0.6630.37
139_V179_R0.6630.37
57_M69_K0.6590.37
52_V72_C0.6560.37
83_V109_I0.6550.36
83_V190_N0.6500.36
72_C96_A0.6470.36
83_V161_V0.6450.36
60_R69_K0.6430.35
126_H132_S0.6420.35
52_V156_E0.6410.35
53_L85_Y0.6350.35
93_V97_I0.6340.35
96_A151_G0.6310.35
98_Q179_R0.6300.34
133_T140_D0.6210.34
81_G89_R0.6190.34
128_V167_I0.6190.34
44_L193_R0.6150.33
37_E41_V0.6120.33
81_G84_G0.6110.33
66_R81_G0.6100.33
204_A207_E0.6100.33
130_L154_G0.6080.33
37_E59_Q0.6060.33
39_E45_L0.6040.32
64_S68_V0.6030.32
76_I161_V0.6030.32
150_L154_G0.6010.32
100_A172_T0.6010.32
40_I114_G0.5950.32
97_I189_F0.5930.32
66_R71_R0.5870.31
37_E40_I0.5860.31
84_G149_G0.5840.31
40_I160_H0.5840.31
110_D165_A0.5800.31
89_R173_R0.5780.30
81_G166_G0.5780.30
71_R79_R0.5740.30
62_T98_Q0.5670.30
48_L85_Y0.5640.29
135_K190_N0.5580.29
70_F188_T0.5580.29
97_I185_A0.5540.29
125_P169_D0.5520.29
124_R145_P0.5520.29
74_V143_L0.5500.28
196_S199_R0.5490.28
79_R168_D0.5480.28
105_K139_V0.5480.28
42_D143_L0.5470.28
50_D101_I0.5470.28
109_I112_S0.5460.28
56_N182_V0.5430.28
49_D174_S0.5420.28
148_R168_D0.5420.28
67_R182_V0.5410.28
56_N73_V0.5410.28
153_A171_W0.5400.28
85_Y100_A0.5380.28
203_H206_E0.5370.28
59_Q67_R0.5320.27
66_R144_M0.5320.27
46_P127_T0.5320.27
92_Q136_A0.5290.27
163_E197_E0.5280.27
45_L59_Q0.5260.27
57_M63_D0.5250.27
114_G125_P0.5230.27
111_V193_R0.5210.26
144_M172_T0.5190.26
134_G152_L0.5170.26
164_L180_T0.5170.26
200_V204_A0.5160.26
162_L172_T0.5160.26
67_R142_E0.5150.26
147_P152_L0.5150.26
53_L193_R0.5150.26
64_S155_G0.5140.26
42_D91_D0.5110.26
93_V153_A0.5070.25
91_D135_K0.5020.25
71_R182_V0.5020.25
89_R107_N0.5000.25
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3j20F 1 0.9481 100 0.064 Contact Map
4kzyC 1 0.9906 100 0.073 Contact Map
3j80C 1 0.967 100 0.074 Contact Map
3j38C 1 0.9858 100 0.076 Contact Map
3j60C 1 0.967 100 0.076 Contact Map
4ujpD 1 0.967 100 0.077 Contact Map
4bpeE 1 0.9764 100 0.079 Contact Map
3zeyP 1 0.9764 100 0.08 Contact Map
3j7aG 1 0.9717 100 0.083 Contact Map
5a2qC 1 0.967 100 0.11 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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