GREMLIN Database
RL30 - 50S ribosomal protein L30P
UniProt: Q9HPB3 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 154 (151)
Sequences: 682 (423)
Seq/√Len: 34.4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
3_A32_C6.7511.00
48_V52_V4.3721.00
56_E140_K3.5511.00
96_L110_A3.4661.00
106_T109_D3.1451.00
72_P79_V2.8631.00
24_L48_V2.8191.00
145_E148_H2.7771.00
61_V150_L2.7081.00
3_A150_L2.5971.00
140_K143_T2.5331.00
63_T94_A2.2930.99
60_A64_D2.2890.99
20_T44_M2.1280.99
132_A145_E2.1070.99
57_P62_L2.0570.98
81_D93_V1.9880.98
2_Q37_E1.8520.97
72_P112_L1.8060.96
30_N125_H1.7860.96
20_T47_K1.7650.96
17_I21_L1.6800.95
53_A141_H1.6710.94
121_P124_G1.5560.92
4_L35_V1.5270.91
82_A85_A1.5050.91
53_A140_K1.4800.90
90_Y99_A1.4640.89
59_E63_T1.4620.89
37_E42_S1.4530.89
59_E98_G1.4510.89
39_D43_G1.4030.87
149_L153_M1.3840.87
73_A114_P1.3800.86
126_D137_Q1.3790.86
13_M17_I1.3480.85
32_C150_L1.3310.84
14_S17_I1.3170.84
85_A93_V1.3000.83
62_L101_L1.2910.82
19_D23_M1.2800.82
81_D84_V1.2380.80
30_N69_R1.2130.78
91_D95_D1.2100.78
82_A95_D1.2070.78
130_T138_L1.2040.78
58_S64_D1.2010.77
12_D129_K1.1990.77
15_R18_Q1.1960.77
15_R19_D1.1910.77
131_P134_D1.1820.76
54_F140_K1.1810.76
141_H147_D1.1810.76
121_P125_H1.1770.76
98_G102_A1.1750.76
25_N69_R1.1710.76
46_A49_N1.1650.75
74_S84_V1.1400.74
70_G73_A1.1310.73
28_S31_H1.1290.73
132_A135_G1.1280.73
133_S143_T1.1210.72
23_M44_M1.1190.72
79_V112_L1.1040.71
64_D151_T1.0840.70
144_E148_H1.0800.70
18_Q22_E1.0580.68
31_H115_V1.0570.68
7_V52_V1.0400.67
4_L149_L1.0300.66
30_N122_R1.0260.66
30_N120_P1.0170.65
35_V41_Y1.0140.65
8_R12_D1.0140.65
64_D68_S0.9840.62
99_A104_E0.9670.61
6_Q141_H0.9650.61
66_I100_L0.9580.60
46_A143_T0.9500.59
127_G130_T0.9500.59
58_S147_D0.9500.59
23_M102_A0.9490.59
137_Q141_H0.9350.58
33_A115_V0.9150.57
33_A84_V0.9090.56
27_H115_V0.9070.56
35_V126_D0.9010.55
125_H137_Q0.8990.55
22_E27_H0.8920.55
74_S96_L0.8820.54
4_L45_V0.8810.54
73_A77_G0.8790.54
76_A84_V0.8740.53
72_P109_D0.8710.53
82_A86_E0.8700.53
3_A61_V0.8620.52
17_I123_G0.8610.52
22_E28_S0.8600.52
58_S151_T0.8570.52
124_G127_G0.8560.52
27_H31_H0.8540.51
138_L150_L0.8030.47
67_E81_D0.8000.47
123_G131_P0.7880.46
120_P130_T0.7870.46
57_P116_I0.7850.46
95_D98_G0.7810.45
83_W119_H0.7770.45
8_R23_M0.7770.45
15_R23_M0.7610.44
88_T106_T0.7500.43
66_I79_V0.7390.42
126_D133_S0.7390.42
42_S46_A0.7380.42
100_L107_L0.7360.41
20_T35_V0.7350.41
10_P144_E0.7330.41
15_R38_T0.7290.41
6_Q116_I0.7240.40
9_G21_L0.7230.40
127_G135_G0.7220.40
84_V93_V0.7200.40
120_P125_H0.7110.39
68_S104_E0.7110.39
38_T128_I0.7100.39
39_D76_A0.7070.39
34_L100_L0.7060.39
11_V45_V0.7010.39
70_G113_A0.7000.39
7_V123_G0.6940.38
30_N153_M0.6930.38
121_P136_G0.6920.38
136_G139_G0.6890.38
66_I112_L0.6840.37
18_Q24_L0.6780.37
32_C61_V0.6760.37
17_I137_Q0.6730.36
58_S61_V0.6710.36
66_I146_I0.6680.36
98_G107_L0.6570.35
17_I20_T0.6540.35
5_V93_V0.6530.35
78_D116_I0.6520.35
29_V125_H0.6500.35
2_Q42_S0.6480.34
143_T149_L0.6450.34
137_Q140_K0.6440.34
96_L100_L0.6430.34
6_Q9_G0.6390.34
44_M53_A0.6370.34
4_L41_Y0.6340.33
128_I152_D0.6320.33
40_T102_A0.6280.33
77_G145_E0.6270.33
92_D95_D0.6240.33
20_T33_A0.6230.33
2_Q56_E0.6230.33
71_E114_P0.6190.32
5_V52_V0.6150.32
64_D98_G0.6150.32
125_H132_A0.6130.32
63_T68_S0.6130.32
10_P31_H0.6120.32
24_L35_V0.6080.31
49_N54_F0.6080.31
86_E91_D0.6080.31
80_D111_G0.6060.31
4_L40_T0.6050.31
99_A107_L0.6040.31
90_Y98_G0.6020.31
59_E68_S0.6010.31
17_I122_R0.6000.31
79_V84_V0.5980.31
5_V20_T0.5970.31
37_E47_K0.5970.31
111_G115_V0.5930.30
30_N105_T0.5890.30
28_S117_R0.5880.30
114_P117_R0.5880.30
148_H152_D0.5830.30
57_P107_L0.5810.29
107_L113_A0.5790.29
85_A101_L0.5740.29
67_E135_G0.5740.29
88_T109_D0.5740.29
2_Q54_F0.5730.29
48_V138_L0.5680.29
18_Q67_E0.5670.29
35_V123_G0.5640.28
57_P95_D0.5590.28
34_L62_L0.5570.28
93_V132_A0.5560.28
75_G83_W0.5560.28
7_V147_D0.5540.28
124_G136_G0.5540.28
59_E89_E0.5530.28
47_K129_K0.5530.28
59_E112_L0.5520.27
133_S140_K0.5490.27
55_G146_I0.5490.27
62_L65_L0.5480.27
92_D151_T0.5450.27
5_V53_A0.5440.27
136_G149_L0.5420.27
66_I110_A0.5420.27
62_L103_E0.5400.27
14_S109_D0.5400.27
119_H122_R0.5380.27
36_P108_S0.5370.26
24_L52_V0.5350.26
119_H138_L0.5310.26
20_T24_L0.5280.26
51_Y151_T0.5270.26
10_P29_V0.5170.25
82_A98_G0.5160.25
28_S135_G0.5150.25
122_R127_G0.5150.25
43_G153_M0.5140.25
24_L38_T0.5130.25
63_T145_E0.5130.25
80_D92_D0.5120.25
7_V137_Q0.5080.25
64_D91_D0.5070.25
26_I33_A0.5030.24
7_V15_R0.5010.24
7_V37_E0.5000.24
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2zkrw 1 0.9805 100 0.094 Contact Map
3j65r 2 0.9935 100 0.098 Contact Map
3zf7w 1 0.9935 100 0.116 Contact Map
3j61F 1 0.9935 100 0.117 Contact Map
4a17V 1 0.9935 100 0.121 Contact Map
1vq8W 1 0.9935 100 0.123 Contact Map
3j39F 1 0.9935 100 0.124 Contact Map
4ujqI 1 0.9935 100 0.124 Contact Map
4w20F 1 0.9935 100 0.125 Contact Map
1vx75 1 0.9935 100 0.13 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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