GREMLIN Database
Q9HP90 - Uncharacterized protein
UniProt: Q9HP90 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 143 (134)
Sequences: 20874 (16938)
Seq/√Len: 1463.3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
34_D84_Y3.2271.00
91_A126_D2.8701.00
4_R34_D2.8631.00
6_L103_A2.8051.00
32_T82_E2.5751.00
21_H136_L2.5571.00
4_R32_T2.3841.00
84_Y97_V2.3791.00
105_L136_L2.3581.00
106_V133_T2.1021.00
71_A83_T2.0001.00
97_V101_D1.9901.00
108_M127_V1.9811.00
34_D82_E1.9371.00
86_R93_E1.9241.00
34_D103_A1.8631.00
125_R129_E1.8531.00
34_D101_D1.8381.00
110_T139_P1.7861.00
88_G93_E1.7591.00
34_D97_V1.7531.00
38_V93_E1.7161.00
8_P94_I1.7061.00
32_T80_D1.6821.00
36_L97_V1.6751.00
7_L22_A1.6731.00
8_P108_M1.6001.00
93_E96_A1.5041.00
20_E73_R1.4931.00
25_V29_R1.4871.00
71_A75_S1.4821.00
98_L106_V1.4671.00
37_Y63_G1.4651.00
31_A104_D1.4521.00
95_L130_S1.4041.00
106_V131_T1.3771.00
86_R97_V1.3701.00
16_D73_R1.3461.00
126_D130_S1.3111.00
60_R64_E1.3081.00
7_L19_V1.3021.00
64_E68_E1.2581.00
90_P123_V1.2381.00
106_V127_V1.2151.00
22_A26_A1.1851.00
36_L86_R1.1671.00
4_R104_D1.1441.00
97_V100_E1.1361.00
115_F119_M1.1181.00
63_G66_A1.1081.00
68_E83_T1.1061.00
73_R77_A1.1041.00
21_H138_V1.0721.00
68_E71_A1.0701.00
66_A70_A1.0571.00
9_V70_A1.0341.00
131_T135_V1.0231.00
19_V35_V1.0201.00
5_I105_L1.0191.00
21_H25_V1.0151.00
108_M124_S0.9931.00
59_L62_Q0.9911.00
67_V83_T0.9881.00
110_T137_T0.9871.00
128_V137_T0.9861.00
66_A69_H0.9841.00
22_A107_V0.9771.00
68_E72_D0.9671.00
56_T60_R0.9521.00
70_A73_R0.9471.00
11_D37_Y0.9461.00
29_R104_D0.9431.00
38_V90_P0.9321.00
36_L94_I0.9271.00
97_V103_A0.9261.00
4_R103_A0.9191.00
114_D117_Q0.9101.00
4_R101_D0.9081.00
39_L87_D0.9081.00
35_V81_T0.9051.00
98_L133_T0.9011.00
21_H24_D0.8981.00
61_T65_R0.8981.00
15_M18_V0.8971.00
19_V70_A0.8971.00
37_Y66_A0.8941.00
12_S15_M0.8891.00
110_T124_S0.8861.00
39_L85_V0.8801.00
117_Q125_R0.8731.00
96_A100_E0.8691.00
24_D28_R0.8651.00
63_G67_V0.8591.00
23_A79_V0.8571.00
70_A74_L0.8551.00
16_D20_E0.8531.00
112_R116_E0.8531.00
16_D69_H0.8401.00
86_R100_E0.8371.00
57_A61_T0.8281.00
124_S137_T0.8261.00
22_A33_V0.8251.00
51_M54_E0.8251.00
23_A74_L0.8191.00
21_H134_P0.8181.00
84_Y101_D0.8181.00
62_Q66_A0.8071.00
69_H73_R0.8061.00
35_V70_A0.7971.00
95_L131_T0.7941.00
17_R20_E0.7921.00
95_L127_V0.7921.00
9_V35_V0.7921.00
9_V16_D0.7891.00
6_L36_L0.7861.00
23_A77_A0.7831.00
98_L103_A0.7801.00
9_V18_V0.7771.00
6_L97_V0.7771.00
107_V136_L0.7771.00
73_R76_E0.7711.00
26_A33_V0.7531.00
6_L106_V0.7471.00
89_D92_D0.7351.00
9_V19_V0.7281.00
27_G78_G0.7271.00
63_G85_V0.7191.00
54_E58_Q0.7101.00
53_D57_A0.7061.00
16_D70_A0.7051.00
52_Q55_A0.7031.00
8_P109_G0.6991.00
35_V74_L0.6991.00
94_I127_V0.6971.00
59_L63_G0.6951.00
91_A123_V0.6941.00
14_S17_R0.6861.00
58_Q62_Q0.6851.00
114_D118_S0.6831.00
53_D56_T0.6821.00
39_L63_G0.6791.00
64_E83_T0.6781.00
74_L77_A0.6761.00
61_T64_E0.6761.00
69_H72_D0.6751.00
9_V15_M0.6751.00
19_V23_A0.6751.00
26_A31_A0.6701.00
62_Q65_R0.6701.00
95_L98_L0.6651.00
24_D27_G0.6641.00
107_V138_V0.6631.00
25_V28_R0.6631.00
67_V71_A0.6621.00
74_L81_T0.6561.00
65_R69_H0.6481.00
7_L33_V0.6481.00
115_F118_S0.6441.00
55_A58_Q0.6411.00
36_L93_E0.6401.00
23_A27_G0.6341.00
58_Q61_T0.6341.00
54_E57_A0.6331.00
71_A81_T0.6311.00
22_A31_A0.6301.00
91_A95_L0.6251.00
108_M137_T0.6251.00
72_D76_E0.6241.00
26_A29_R0.6181.00
11_D66_A0.6141.00
5_I26_A0.6081.00
102_G133_T0.6071.00
91_A127_V0.6061.00
5_I107_V0.6051.00
93_E97_V0.5991.00
57_A60_R0.5981.00
109_G138_V0.5971.00
72_D75_S0.5861.00
27_G77_A0.5811.00
20_E77_A0.5801.00
120_L124_S0.5791.00
7_L18_V0.5661.00
18_V107_V0.5601.00
10_D15_M0.5551.00
52_Q56_T0.5471.00
45_L49_D0.5421.00
25_V107_V0.5411.00
11_D70_A0.5371.00
91_A130_S0.5361.00
111_R124_S0.5331.00
60_R87_D0.5321.00
71_A74_L0.5311.00
67_V70_A0.5241.00
23_A73_R0.5171.00
38_V88_G0.5161.00
43_A46_T0.5141.00
55_A59_L0.5091.00
17_R21_H0.5071.00
51_M55_A0.5041.00
8_P90_P0.5011.00
127_V135_V0.5001.00
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1mjhA 2 0.965 99.9 0.171 Contact Map
4wnyA 2 0.8811 99.9 0.171 Contact Map
3s3tA 4 0.972 99.9 0.174 Contact Map
5ahwA 4 0.986 99.9 0.175 Contact Map
2dumA 2 0.972 99.9 0.179 Contact Map
2gm3A 2 0.8881 99.9 0.18 Contact Map
3hgmA 2 0.965 99.9 0.19 Contact Map
3tnjA 2 0.8741 99.9 0.194 Contact Map
1jmvA 4 0.972 99.9 0.205 Contact Map
3loqA 1 0.965 99.9 0.207 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0061 seconds.