Q9HP88 - HALSA - GREMLIN Contacts

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Q9HP88 - Phytoene dehydrogenase

UniProt:	Q9HP88	Sequences: MPHQSQPGFLLPAIQHHSMQGSLPGERDVTVVGGGFGGLAAAAYLARAGASVTLLEQHDTVGGRAGVLERDGFRFDTGPSWYLMPDVFERFFDHFDHDPHDFYELTRLDPQYRVFWTDGDSATIEPNRRNAHELFESYEEGAGDALATYLDRAATNYDLAMNRVVYPDRTAFRDYASTDMLPLASRLRLFGNMDDYVSRFFDHPKLRQLLEYTLVFLGGAPHNTPALYSIMSHVDLNGNVFYPEGGIAGVVDALAELAVEQGATIETGVGVNAISGRRGEFTLATDDGTRTTDLVVNNANPAYAERELLDTGGRDHAPDYWDDQTYAPSALMFYLGVEGDVEPLAHHSLVLPPDWDGHFAQLFDDPGWPDDPAFYLSVASKTDDTVAPDGHEAVVILLPIAPGLDDTPEIRAQYRDRLLGTLAAQTGVDLRDRIVVEESACVSEFSEQFGDPGGTALGLAHTLFQTGPLRPGKRDGPDGHYYVGAYTNPGIGMPMCLISGEHVTKAVIDDDPAASGSTDPLAVPGEFNFDTPTTAD	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	536 (459)
Sequences:	14106 (11141)
Seq/√Len:	520.0

BACSU - YOBN PPOX
HALSA - Q9HP88 Q9HPD8 Q9HSE1 Q9HRU3 Q9HP54
SULSO - Q97W24 Q97UT6 Q97YW3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
28_D	51_S	4.574	1.00
30_T	292_T	4.396	1.00
258_A	263_A	4.039	1.00
28_D	293_D	3.959	1.00
53_T	266_E	3.863	1.00
57_Q	270_G	3.800	1.00
61_V	267_T	3.657	1.00
41_A	296_V	3.630	1.00
273_A	284_A	3.538	1.00
104_E	244_E	3.362	1.00
30_T	55_L	3.262	1.00
500_G	504_T	3.091	1.00
297_N	304_A	3.078	1.00
61_V	255_A	2.987	1.00
34_G	61_V	2.944	1.00
59_D	268_G	2.882	1.00
275_S	284_A	2.806	1.00
51_S	264_T	2.725	1.00
410_I	413_Q	2.678	1.00
248_A	252_D	2.602	1.00
269_V	285_T	2.569	1.00
30_T	283_L	2.564	1.00
55_L	266_E	2.553	1.00
249_G	252_D	2.541	1.00
32_V	297_N	2.531	1.00
255_A	259_V	2.443	1.00
191_G	199_R	2.440	1.00
272_N	286_D	2.399	1.00
423_A	431_R	2.382	1.00
298_N	483_V	2.344	1.00
29_V	50_A	2.318	1.00
255_A	265_I	2.314	1.00
266_E	269_V	2.298	1.00
481_Y	510_D	2.292	1.00
270_G	286_D	2.251	1.00
44_Y	501_E	2.245	1.00
28_D	53_T	2.237	1.00
55_L	292_T	2.221	1.00
69_E	74_R	2.218	1.00
284_A	290_R	2.179	1.00
294_L	481_Y	2.159	1.00
32_V	299_A	2.145	1.00
132_H	147_A	2.114	1.00
48_A	508_I	2.110	1.00
36_F	493_M	2.105	1.00
253_A	256_E	2.087	1.00
194_D	198_S	2.083	1.00
134_L	137_S	2.071	1.00
282_T	291_T	2.056	1.00
106_T	244_E	2.028	1.00
37_G	298_N	2.017	1.00
40_A	497_L	2.016	1.00
296_V	507_V	1.995	1.00
27_R	53_T	1.991	1.00
391_H	435_V	1.956	1.00
60_T	66_G	1.952	1.00
277_R	282_T	1.934	1.00
416_D	420_G	1.925	1.00
44_Y	47_R	1.898	1.00
67_V	74_R	1.877	1.00
50_A	508_I	1.876	1.00
29_V	294_L	1.865	1.00
272_N	284_A	1.862	1.00
192_N	195_D	1.857	1.00
423_A	429_D	1.843	1.00
44_Y	505_K	1.812	1.00
43_A	257_L	1.798	1.00
198_S	207_R	1.788	1.00
275_S	282_T	1.786	1.00
269_V	287_D	1.764	1.00
285_T	288_G	1.761	1.00
338_E	433_R	1.757	1.00
339_G	433_R	1.748	1.00
412_A	416_D	1.740	1.00
47_R	94_H	1.735	1.00
55_L	271_V	1.730	1.00
266_E	289_T	1.726	1.00
483_V	503_V	1.707	1.00
281_F	295_V	1.695	1.00
42_A	54_L	1.680	1.00
53_T	264_T	1.660	1.00
93_D	98_D	1.654	1.00
299_A	304_A	1.634	1.00
338_E	435_V	1.627	1.00
415_R	437_E	1.591	1.00
349_L	352_P	1.580	1.00
338_E	391_H	1.564	1.00
61_V	265_I	1.557	1.00
61_V	251_V	1.547	1.00
281_F	479_G	1.546	1.00
28_D	50_A	1.538	1.00
194_D	222_H	1.516	1.00
252_D	256_E	1.514	1.00
90_R	501_E	1.510	1.00
258_A	265_I	1.509	1.00
274_I	281_F	1.505	1.00
65_A	251_V	1.504	1.00
53_T	292_T	1.468	1.00
73_F	336_G	1.467	1.00
38_G	298_N	1.451	1.00
54_L	265_I	1.450	1.00
29_V	45_L	1.449	1.00
89_E	93_D	1.445	1.00
34_G	54_L	1.444	1.00
257_L	261_Q	1.444	1.00
247_I	493_M	1.432	1.00
397_L	400_I	1.428	1.00
30_T	53_T	1.424	1.00
259_V	264_T	1.420	1.00
31_V	42_A	1.416	1.00
43_A	47_R	1.412	1.00
337_V	419_L	1.399	1.00
120_D	205_K	1.398	1.00
37_G	499_S	1.391	1.00
294_L	507_V	1.386	1.00
271_V	283_L	1.384	1.00
292_T	295_V	1.383	1.00
127_N	130_N	1.366	1.00
481_Y	503_V	1.361	1.00
148_T	152_R	1.355	1.00
429_D	432_D	1.349	1.00
46_A	263_A	1.349	1.00
26_E	51_S	1.337	1.00
191_G	195_D	1.336	1.00
256_E	259_V	1.320	1.00
125_E	130_N	1.319	1.00
420_G	431_R	1.310	1.00
55_L	285_T	1.309	1.00
44_Y	94_H	1.300	1.00
273_A	310_D	1.292	1.00
145_A	148_T	1.291	1.00
276_G	281_F	1.291	1.00
46_A	261_Q	1.291	1.00
243_P	250_V	1.289	1.00
144_D	148_T	1.286	1.00
183_L	186_R	1.286	1.00
27_R	293_D	1.282	1.00
55_L	269_V	1.279	1.00
406_D	409_E	1.275	1.00
31_V	52_V	1.268	1.00
503_V	506_A	1.267	1.00
416_D	431_R	1.264	1.00
113_R	123_T	1.255	1.00
275_S	290_R	1.255	1.00
46_A	52_V	1.248	1.00
90_R	94_H	1.243	1.00
409_E	413_Q	1.240	1.00
154_A	158_D	1.233	1.00
252_D	255_A	1.231	1.00
301_P	486_Y	1.230	1.00
259_V	262_G	1.230	1.00
69_E	248_A	1.229	1.00
300_N	303_Y	1.215	1.00
413_Q	416_D	1.212	1.00
43_A	254_L	1.209	1.00
36_F	65_A	1.205	1.00
64_R	485_A	1.202	1.00
502_H	506_A	1.202	1.00
87_V	501_E	1.200	1.00
315_D	477_P	1.196	1.00
26_E	293_D	1.194	1.00
45_L	504_T	1.188	1.00
151_D	154_A	1.185	1.00
255_A	267_T	1.171	1.00
257_L	260_E	1.169	1.00
27_R	51_S	1.168	1.00
69_E	72_G	1.168	1.00
274_I	295_V	1.167	1.00
139_E	142_A	1.167	1.00
280_E	291_T	1.166	1.00
481_Y	506_A	1.163	1.00
415_R	419_L	1.160	1.00
335_L	419_L	1.157	1.00
26_E	291_T	1.146	1.00
429_D	433_R	1.142	1.00
487_T	499_S	1.134	1.00
43_A	258_A	1.131	1.00
73_F	388_P	1.127	1.00
421_T	424_A	1.123	1.00
41_A	500_G	1.122	1.00
427_G	430_L	1.121	1.00
220_A	223_N	1.120	1.00
37_G	483_V	1.113	1.00
474_R	510_D	1.113	1.00
44_Y	500_G	1.112	1.00
501_E	505_K	1.111	1.00
299_A	308_L	1.108	1.00
285_T	289_T	1.107	1.00
249_G	253_A	1.102	1.00
256_E	260_E	1.096	1.00
419_L	423_A	1.096	1.00
481_Y	507_V	1.093	1.00
148_T	151_D	1.088	1.00
434_I	437_E	1.085	1.00
168_D	171_A	1.081	1.00
318_P	322_D	1.071	1.00
43_A	94_H	1.070	1.00
130_N	133_E	1.065	1.00
417_R	420_G	1.064	1.00
230_I	236_L	1.063	1.00
68_L	77_T	1.059	1.00
46_A	258_A	1.059	1.00
428_V	431_R	1.059	1.00
398_L	418_L	1.059	1.00
487_T	502_H	1.058	1.00
282_T	290_R	1.058	1.00
97_H	260_E	1.046	1.00
372_P	378_V	1.045	1.00
221_P	224_T	1.045	1.00
277_R	291_T	1.042	1.00
413_Q	417_R	1.041	1.00
53_T	293_D	1.029	1.00
310_D	313_G	1.022	1.00
232_S	236_L	1.020	1.00
277_R	280_E	1.016	1.00
503_V	507_V	1.014	1.00
420_G	424_A	1.014	1.00
151_D	155_T	1.013	1.00
37_G	496_C	1.011	1.00
303_Y	306_R	1.011	1.00
297_N	480_H	1.011	1.00
157_Y	160_A	1.009	1.00
44_Y	48_A	0.989	1.00
273_A	311_T	0.986	1.00
204_P	208_Q	0.986	1.00
58_H	448_Q	0.979	1.00
276_G	479_G	0.978	1.00
294_L	479_G	0.977	1.00
34_G	267_T	0.976	1.00
154_A	157_Y	0.970	1.00
272_N	275_S	0.969	1.00
415_R	418_L	0.967	1.00
58_H	66_G	0.965	1.00
144_D	147_A	0.963	1.00
222_H	225_P	0.963	1.00
472_G	475_D	0.962	1.00
371_D	424_A	0.961	1.00
90_R	93_D	0.958	1.00
274_I	297_N	0.957	1.00
229_S	237_N	0.957	1.00
152_R	155_T	0.951	1.00
245_G	249_G	0.951	1.00
484_G	499_S	0.948	1.00
310_D	314_R	0.946	1.00
243_P	249_G	0.944	1.00
47_R	261_Q	0.936	1.00
95_F	254_L	0.933	1.00
40_A	500_G	0.930	1.00
28_D	291_T	0.928	1.00
58_H	452_P	0.922	1.00
73_F	391_H	0.922	1.00
70_R	438_E	0.922	1.00
54_L	258_A	0.921	1.00
274_I	283_L	0.919	1.00
36_F	496_C	0.919	1.00
92_F	97_H	0.918	1.00
27_R	30_T	0.914	1.00
88_F	497_L	0.914	1.00
319_D	322_D	0.912	1.00
272_N	285_T	0.910	1.00
275_S	311_T	0.910	1.00
233_H	236_L	0.910	1.00
172_F	175_Y	0.908	1.00
67_V	248_A	0.905	1.00
348_S	352_P	0.903	1.00
155_T	158_D	0.903	1.00
50_A	53_T	0.899	1.00
87_V	90_R	0.896	1.00
196_Y	200_F	0.896	1.00
505_K	509_D	0.892	1.00
32_V	271_V	0.892	1.00
396_I	400_I	0.891	1.00
42_A	258_A	0.890	1.00
198_S	203_H	0.890	1.00
474_R	506_A	0.886	1.00
319_D	323_D	0.883	1.00
269_V	289_T	0.882	1.00
420_G	423_A	0.881	1.00
423_A	432_D	0.878	1.00
146_L	149_Y	0.875	1.00
335_L	396_I	0.874	1.00
504_T	507_V	0.874	1.00
374_F	377_S	0.872	1.00
31_V	296_V	0.869	1.00
50_A	293_D	0.868	1.00
395_V	400_I	0.866	1.00
91_F	95_F	0.866	1.00
49_G	52_V	0.865	1.00
496_C	500_G	0.863	1.00
43_A	95_F	0.862	1.00
422_L	430_L	0.860	1.00
411_R	442_V	0.855	1.00
251_V	255_A	0.854	1.00
219_G	225_P	0.854	1.00
461_H	464_F	0.852	1.00
51_S	293_D	0.851	1.00
375_Y	379_A	0.848	1.00
149_Y	152_R	0.847	1.00
57_Q	451_D	0.847	1.00
55_L	283_L	0.846	1.00
395_V	399_P	0.845	1.00
147_A	151_D	0.845	1.00
56_E	267_T	0.841	1.00
333_F	439_S	0.840	1.00
232_S	235_D	0.838	1.00
270_G	451_D	0.835	1.00
462_T	465_Q	0.835	1.00
233_H	237_N	0.833	1.00
220_A	225_P	0.830	1.00
373_A	376_L	0.828	1.00
229_S	232_S	0.825	1.00
136_E	141_G	0.824	1.00
218_G	226_A	0.821	1.00
483_V	500_G	0.817	1.00
219_G	223_N	0.816	1.00
133_E	137_S	0.816	1.00
171_A	174_D	0.815	1.00
54_L	61_V	0.815	1.00
295_V	479_G	0.814	1.00
443_S	446_S	0.814	1.00
197_V	211_E	0.811	1.00
415_R	439_S	0.809	1.00
105_L	108_L	0.807	1.00
229_S	236_L	0.802	1.00
36_F	251_V	0.801	1.00
104_E	107_R	0.800	1.00
64_R	78_G	0.800	1.00
301_P	321_W	0.800	1.00
395_V	398_L	0.798	1.00
103_Y	106_T	0.795	1.00
412_A	415_R	0.795	1.00
230_I	234_V	0.792	1.00
221_P	225_P	0.789	1.00
48_A	505_K	0.787	1.00
155_T	159_L	0.786	1.00
228_Y	236_L	0.785	1.00
172_F	176_A	0.784	1.00
65_A	79_P	0.784	1.00
375_Y	378_V	0.784	1.00
173_R	176_A	0.783	1.00
31_V	38_G	0.783	1.00
40_A	91_F	0.780	1.00
27_R	50_A	0.774	1.00
167_P	170_T	0.772	1.00
125_E	134_L	0.771	1.00
143_G	147_A	0.771	1.00
152_R	156_N	0.771	1.00
133_E	136_E	0.770	1.00
477_P	480_H	0.769	1.00
184_A	187_L	0.768	1.00
40_A	44_Y	0.765	1.00
39_L	54_L	0.765	1.00
147_A	150_L	0.764	1.00
283_L	295_V	0.763	1.00
309_L	313_G	0.763	1.00
87_V	498_I	0.762	1.00
43_A	261_Q	0.761	1.00
218_G	223_N	0.760	1.00
36_F	40_A	0.758	1.00
280_E	478_D	0.758	1.00
309_L	312_G	0.756	1.00
129_R	132_H	0.755	1.00
40_A	254_L	0.755	1.00
416_D	437_E	0.754	1.00
229_S	235_D	0.754	1.00
228_Y	232_S	0.753	1.00
374_F	378_V	0.752	1.00
73_F	435_V	0.751	1.00
300_N	452_P	0.750	1.00
41_A	503_V	0.748	1.00
336_G	391_H	0.747	1.00
301_P	305_E	0.747	1.00
296_V	481_Y	0.746	1.00
36_F	497_L	0.746	1.00
191_G	196_Y	0.745	1.00
416_D	419_L	0.745	1.00
46_A	264_T	0.745	1.00
224_T	229_S	0.744	1.00
317_A	476_G	0.743	1.00
28_D	292_T	0.740	1.00
371_D	421_T	0.738	1.00
336_G	436_V	0.738	1.00
504_T	508_I	0.737	1.00
142_A	145_A	0.737	1.00
171_A	175_Y	0.735	1.00
302_A	306_R	0.732	1.00
128_R	132_H	0.731	1.00
146_L	152_R	0.730	1.00
306_R	453_G	0.730	1.00
378_V	381_K	0.727	1.00
47_R	257_L	0.725	1.00
348_S	353_P	0.724	1.00
430_L	433_R	0.718	1.00
39_L	258_A	0.717	1.00
131_A	134_L	0.717	1.00
299_A	303_Y	0.715	1.00
435_V	438_E	0.714	1.00
173_R	177_S	0.713	1.00
317_A	320_Y	0.712	1.00
46_A	262_G	0.708	1.00
145_A	149_Y	0.708	1.00
397_L	401_A	0.707	1.00
349_L	354_D	0.707	1.00
493_M	497_L	0.706	1.00
498_I	502_H	0.706	1.00
36_F	254_L	0.706	1.00
347_H	351_L	0.706	1.00
463_L	466_T	0.703	1.00
130_N	134_L	0.700	1.00
144_D	155_T	0.700	1.00
296_V	503_V	0.697	1.00
219_G	222_H	0.694	1.00
42_A	263_A	0.694	1.00
348_S	351_L	0.694	1.00
145_A	153_A	0.694	1.00
403_G	406_D	0.694	1.00
270_G	450_G	0.689	1.00
201_F	210_L	0.689	1.00
374_F	379_A	0.687	1.00
380_S	392_E	0.686	1.00
272_N	287_D	0.686	1.00
29_V	507_V	0.686	1.00
76_D	247_I	0.682	1.00
285_T	290_R	0.682	1.00
145_A	152_R	0.682	1.00
197_V	201_F	0.682	1.00
182_P	185_S	0.681	1.00
136_E	143_G	0.680	1.00
79_P	247_I	0.679	1.00
444_E	447_E	0.679	1.00
183_L	187_L	0.677	1.00
440_A	444_E	0.675	1.00
203_H	207_R	0.674	1.00
373_A	379_A	0.673	1.00
283_L	286_D	0.673	1.00
30_T	295_V	0.671	1.00
271_V	285_T	0.671	1.00
65_A	493_M	0.671	1.00
156_N	160_A	0.669	1.00
432_D	435_V	0.668	1.00
144_D	149_Y	0.668	1.00
433_R	436_V	0.667	1.00
221_P	227_L	0.666	1.00
152_R	159_L	0.664	1.00
150_L	153_A	0.663	1.00
91_F	94_H	0.662	1.00
460_A	465_Q	0.661	1.00
392_E	395_V	0.661	1.00
140_E	143_G	0.660	1.00
181_L	184_A	0.659	1.00
222_H	226_A	0.658	1.00
417_R	421_T	0.655	1.00
92_F	243_P	0.653	1.00
158_D	161_M	0.653	1.00
147_A	154_A	0.652	1.00
149_Y	157_Y	0.650	1.00
144_D	151_D	0.650	1.00
419_L	434_I	0.648	1.00
111_Q	114_V	0.648	1.00
396_I	422_L	0.647	1.00
44_Y	91_F	0.646	1.00
131_A	135_F	0.646	1.00
93_D	96_D	0.646	1.00
411_R	441_C	0.644	1.00
219_G	224_T	0.640	1.00
196_Y	226_A	0.640	1.00
149_Y	154_A	0.640	1.00
140_E	144_D	0.639	1.00
441_C	444_E	0.639	1.00
276_G	477_P	0.639	1.00
132_H	136_E	0.638	1.00
80_S	395_V	0.638	1.00
204_P	207_R	0.636	1.00
230_I	235_D	0.636	1.00
331_L	439_S	0.636	1.00
475_D	482_Y	0.636	1.00
478_D	510_D	0.635	1.00
330_A	456_A	0.635	1.00
65_A	247_I	0.635	1.00
398_L	401_A	0.634	1.00
171_A	176_A	0.634	1.00
300_N	486_Y	0.632	1.00
294_L	510_D	0.632	1.00
335_L	415_R	0.632	1.00
308_L	312_G	0.632	1.00
457_L	463_L	0.631	1.00
148_T	154_A	0.631	1.00
264_T	267_T	0.630	1.00
296_V	483_V	0.630	1.00
50_A	294_L	0.629	1.00
207_R	211_E	0.629	1.00
182_P	186_R	0.628	1.00
372_P	379_A	0.628	1.00
71_D	436_V	0.628	1.00
195_D	198_S	0.628	1.00
253_A	257_L	0.627	1.00
335_L	430_L	0.627	1.00
229_S	233_H	0.626	1.00
219_G	226_A	0.626	1.00
87_V	497_L	0.626	1.00
31_V	54_L	0.626	1.00
229_S	234_V	0.626	1.00
165_V	168_D	0.625	1.00
255_A	263_A	0.624	1.00
273_A	309_L	0.623	1.00
208_Q	212_Y	0.623	1.00
259_V	263_A	0.623	1.00
59_D	267_T	0.622	1.00
483_V	499_S	0.621	1.00
343_P	346_H	0.619	1.00
272_N	288_G	0.619	1.00
297_N	482_Y	0.619	1.00
419_L	431_R	0.618	1.00
394_V	397_L	0.617	1.00
221_P	226_A	0.617	1.00
507_V	510_D	0.616	1.00
88_F	494_P	0.616	1.00
228_Y	231_M	0.615	1.00
234_V	237_N	0.614	1.00
215_V	219_G	0.613	1.00
203_H	206_L	0.613	1.00
60_T	248_A	0.608	1.00
399_P	402_P	0.607	1.00
107_R	110_P	0.606	1.00
150_L	156_N	0.605	1.00
211_E	221_P	0.604	1.00
338_E	432_D	0.604	1.00
75_F	336_G	0.604	1.00
294_L	297_N	0.603	1.00
436_V	439_S	0.601	1.00
393_A	397_L	0.600	1.00
232_S	237_N	0.599	1.00
91_F	497_L	0.598	0.99
162_N	165_V	0.598	0.99
347_H	350_V	0.597	0.99
154_A	159_L	0.596	0.99
434_I	438_E	0.596	0.99
87_V	494_P	0.595	0.99
435_V	439_S	0.593	0.99
112_Y	115_F	0.592	0.99
350_V	353_P	0.592	0.99
174_D	177_S	0.591	0.99
419_L	437_E	0.591	0.99
37_G	40_A	0.591	0.99
207_R	212_Y	0.590	0.99
339_G	392_E	0.590	0.99
255_A	258_A	0.588	0.99
150_L	157_Y	0.588	0.99
372_P	377_S	0.587	0.99
231_M	235_D	0.585	0.99
224_T	227_L	0.585	0.99
156_N	159_L	0.584	0.99
373_A	378_V	0.583	0.99
411_R	415_R	0.582	0.99
147_A	152_R	0.581	0.99
79_P	494_P	0.581	0.99
407_T	411_R	0.580	0.99
135_F	139_E	0.579	0.99
336_G	435_V	0.579	0.99
218_G	225_P	0.577	0.99
301_P	324_Q	0.576	0.99
128_R	131_A	0.575	0.99
347_H	352_P	0.575	0.99
479_G	510_D	0.575	0.99
394_V	398_L	0.574	0.99
151_D	158_D	0.571	0.99
427_G	431_R	0.571	0.99
344_L	347_H	0.571	0.99
75_F	334_Y	0.570	0.99
34_G	255_A	0.569	0.99
314_R	318_P	0.569	0.99
438_E	441_C	0.566	0.99
246_G	249_G	0.566	0.99
373_A	421_T	0.565	0.99
158_D	162_N	0.565	0.99
245_G	383_D	0.564	0.99
231_M	237_N	0.564	0.99
197_V	207_R	0.563	0.99
76_D	81_W	0.562	0.99
293_D	479_G	0.562	0.99
194_D	211_E	0.561	0.99
92_F	95_F	0.561	0.99
76_D	248_A	0.560	0.99
224_T	231_M	0.560	0.99
249_G	256_E	0.558	0.99
333_F	415_R	0.558	0.99
181_L	185_S	0.558	0.99
411_R	414_Y	0.557	0.99
88_F	493_M	0.557	0.99
70_R	75_F	0.557	0.99
121_S	124_I	0.557	0.99
167_P	171_A	0.556	0.99
152_R	200_F	0.556	0.99
445_F	451_D	0.556	0.99
394_V	400_I	0.554	0.99
27_R	264_T	0.554	0.99
281_F	480_H	0.554	0.99
141_G	203_H	0.552	0.99
340_D	392_E	0.552	0.99
242_Y	247_I	0.551	0.99
52_V	258_A	0.551	0.99
337_V	341_V	0.550	0.99
321_W	324_Q	0.550	0.99
393_A	400_I	0.549	0.99
39_L	251_V	0.549	0.99
215_V	218_G	0.548	0.99
226_A	229_S	0.548	0.99
148_T	155_T	0.547	0.99
118_D	205_K	0.547	0.99
110_P	113_R	0.547	0.99
27_R	294_L	0.547	0.99
349_L	355_W	0.547	0.99
414_Y	418_L	0.546	0.99
67_V	76_D	0.543	0.99
287_D	290_R	0.542	0.99
428_V	432_D	0.541	0.99
115_F	348_S	0.540	0.99
79_P	83_L	0.540	0.99
369_P	372_P	0.539	0.99
325_T	460_A	0.539	0.99
60_T	252_D	0.539	0.99
380_S	393_A	0.539	0.99
458_G	486_Y	0.538	0.99
305_E	322_D	0.538	0.99
146_L	150_L	0.538	0.99
129_R	133_E	0.538	0.99
159_L	162_N	0.538	0.99
86_D	494_P	0.538	0.99
161_M	164_V	0.536	0.99
350_V	354_D	0.535	0.99
238_G	241_F	0.535	0.99
230_I	233_H	0.534	0.99
231_M	234_V	0.534	0.99
129_R	147_A	0.533	0.99
218_G	221_P	0.533	0.99
317_A	477_P	0.532	0.99
394_V	399_P	0.532	0.99
34_G	39_L	0.530	0.99
460_A	463_L	0.530	0.99
406_D	410_I	0.530	0.99
372_P	376_L	0.530	0.99
151_D	156_N	0.529	0.99
152_R	158_D	0.528	0.99
45_L	507_V	0.528	0.99
43_A	263_A	0.527	0.99
325_T	328_P	0.525	0.99
269_V	290_R	0.524	0.99
105_L	109_D	0.524	0.99
280_E	293_D	0.524	0.99
193_M	229_S	0.523	0.99
502_H	505_K	0.523	0.99
30_T	291_T	0.521	0.99
164_V	167_P	0.521	0.99
252_D	259_V	0.521	0.99
457_L	485_A	0.519	0.99
70_R	336_G	0.518	0.99
491_I	496_C	0.518	0.99
225_P	228_Y	0.517	0.99
76_D	80_S	0.517	0.99
443_S	447_E	0.515	0.99
392_E	396_I	0.513	0.98
393_A	399_P	0.512	0.98
149_Y	153_A	0.511	0.98
436_V	441_C	0.511	0.98
472_G	476_G	0.511	0.98
79_P	493_M	0.511	0.98
222_H	227_L	0.510	0.98
83_L	494_P	0.509	0.98
351_L	354_D	0.508	0.98
337_V	342_E	0.508	0.98
414_Y	417_R	0.508	0.98
80_S	377_S	0.508	0.98
81_W	492_G	0.507	0.98
211_E	222_H	0.507	0.98
331_L	414_Y	0.506	0.98
163_R	167_P	0.505	0.98
149_Y	159_L	0.505	0.98
339_G	342_E	0.505	0.98
88_F	91_F	0.504	0.98
35_G	38_G	0.503	0.98
143_G	150_L	0.503	0.98
457_L	460_A	0.502	0.98
484_G	487_T	0.501	0.98
108_L	111_Q	0.501	0.98
60_T	267_T	0.501	0.98
337_V	394_V	0.500	0.98
141_G	144_D	0.500	0.98
275_S	291_T	0.500	0.98

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4dgkA	1	0.7425	100	0.366	Contact Map
4repA	1	0.9011	100	0.396	Contact Map
4i59A	1	0.7985	100	0.452	Contact Map
2yg5A	2	0.8022	100	0.459	Contact Map
1s3eA	2	0.8526	100	0.471	Contact Map
2ivdA	1	0.7836	100	0.473	Contact Map
1sezA	3	0.791	100	0.484	Contact Map
3i6dA	1	0.7593	100	0.49	Contact Map
2vvmA	2	0.8433	100	0.496	Contact Map
3x0vA	2	0.8563	100	0.499	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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