Q9HP63 - HALSA - GREMLIN Contacts

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Q9HP63 - Pantothenate permease

UniProt:	Q9HP63	Sequences: MVVALAVGLVAYRVTDRDAEDYYLAGRGLGTGVLLFTTFATLLSAFTFFAGPNIAYANGPEWILVMGLMDGVLFGLLWYVLGYRQWLLGKANGYVTLGEMLGDRFGSRGLRGLVAGVSIFWLFPYVMLQQIGAGEALVGLTGGAVPYWAGAGFITLFMVVYVAISGMRGVAWTDTLQGVFMLGITWVAFVWVAAEIAGTTGGLAGALPAEFRALGGGAYSPQWMLSQAIGIAVGVSMFPQVNQRFFVADSKRTLKRTFAIWPLLVVLLFVPAFLMGAWANGVGLPLPDGENIVPILLSEYTPGWFAALVVAGALAAMMSSSDSMLLSGSSYFTRDIYRPFVNADATARREDTLGRVGVAAFAVAAFGGSLLRPGSLLEVGSTAFGGFAQLAPPVALAMYWRRTTKAGMFAGVLGTQAFYLATVFGPPVTLAGVPIIASSYFGWFAQVVGLPLGVVLTVGVSAVTAPSDTENASAYVDALRAD	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	482 (445)
Sequences:	11589 (7309)
Seq/√Len:	346.5

ECOLI - PANF ACTP PUTP YIDK
BACSU - YWCA YHJB OPUE YCGO YODF
HALSA - Q9HP63 Q9HR16
SULSO - Q7LX83 Q97VX6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
414_G	456_L	5.899	1.00
346_T	349_R	4.192	1.00
403_T	457_T	3.905	1.00
250_S	253_T	3.895	1.00
342_N	349_R	3.623	1.00
6_A	10_V	3.459	1.00
190_V	194_A	3.309	1.00
414_G	452_L	3.241	1.00
159_V	362_A	3.218	1.00
458_V	462_A	3.175	1.00
192_V	278_W	3.018	1.00
337_Y	345_A	3.011	1.00
411_G	457_T	3.003	1.00
410_A	460_V	2.982	1.00
456_L	460_V	2.970	1.00
404_T	464_T	2.898	1.00
460_V	464_T	2.824	1.00
102_G	111_R	2.770	1.00
146_P	149_A	2.750	1.00
348_R	352_T	2.744	1.00
418_F	452_L	2.712	1.00
406_A	464_T	2.694	1.00
352_T	356_V	2.685	1.00
396_L	457_T	2.600	1.00
407_G	461_S	2.592	1.00
155_T	366_F	2.543	1.00
197_A	200_T	2.478	1.00
29_L	171_A	2.418	1.00
356_V	360_A	2.388	1.00
20_E	27_R	2.376	1.00
167_M	247_V	2.364	1.00
279_A	292_I	2.362	1.00
249_D	253_T	2.263	1.00
204_A	208_P	2.261	1.00
203_L	206_A	2.252	1.00
205_G	208_P	2.220	1.00
203_L	207_L	2.180	1.00
406_A	410_A	2.078	1.00
21_D	26_G	2.073	1.00
109_G	409_F	2.071	1.00
345_A	349_R	2.058	1.00
410_A	456_L	2.047	1.00
53_N	290_E	2.011	1.00
186_W	190_V	2.010	1.00
400_W	403_T	2.009	1.00
100_M	397_A	2.006	1.00
393_P	408_M	2.003	1.00
212_R	215_G	2.000	1.00
24_L	27_R	1.973	1.00
404_T	407_G	1.970	1.00
152_G	156_L	1.968	1.00
204_A	207_L	1.967	1.00
252_R	256_R	1.911	1.00
105_F	403_T	1.897	1.00
334_R	338_R	1.892	1.00
253_T	256_R	1.889	1.00
363_V	367_G	1.885	1.00
455_V	459_G	1.875	1.00
106_G	109_G	1.871	1.00
45_A	132_G	1.857	1.00
338_R	350_E	1.853	1.00
396_L	454_V	1.850	1.00
295_I	299_E	1.812	1.00
184_I	312_G	1.800	1.00
407_G	460_V	1.781	1.00
198_G	201_G	1.780	1.00
342_N	345_A	1.776	1.00
33_V	175_T	1.775	1.00
417_A	421_A	1.772	1.00
94_Y	103_D	1.772	1.00
158_M	321_S	1.762	1.00
402_R	462_A	1.744	1.00
337_Y	353_L	1.739	1.00
252_R	255_K	1.689	1.00
307_A	311_A	1.688	1.00
404_T	461_S	1.685	1.00
352_T	355_R	1.679	1.00
206_A	209_A	1.673	1.00
400_W	462_A	1.663	1.00
31_T	253_T	1.651	1.00
165_S	169_G	1.641	1.00
407_G	411_G	1.632	1.00
213_A	216_G	1.623	1.00
332_F	336_I	1.619	1.00
78_W	82_G	1.611	1.00
410_A	414_G	1.606	1.00
400_W	458_V	1.546	1.00
349_R	352_T	1.519	1.00
332_F	357_G	1.515	1.00
325_L	362_A	1.497	1.00
36_F	175_T	1.495	1.00
337_Y	342_N	1.495	1.00
414_G	418_F	1.489	1.00
207_L	210_E	1.489	1.00
99_E	335_D	1.480	1.00
148_W	370_L	1.463	1.00
156_L	160_V	1.449	1.00
18_D	21_D	1.439	1.00
134_G	151_A	1.433	1.00
135_E	288_D	1.430	1.00
402_R	465_A	1.429	1.00
211_F	214_L	1.422	1.00
78_W	83_Y	1.406	1.00
34_L	248_A	1.390	1.00
116_G	336_I	1.382	1.00
99_E	334_R	1.382	1.00
451_P	455_V	1.382	1.00
149_A	152_G	1.372	1.00
106_G	405_K	1.369	1.00
295_I	298_S	1.368	1.00
197_A	201_G	1.368	1.00
337_Y	349_R	1.368	1.00
174_D	244_R	1.365	1.00
8_G	11_A	1.352	1.00
113_L	409_F	1.349	1.00
158_M	318_M	1.347	1.00
351_D	355_R	1.334	1.00
328_G	361_F	1.332	1.00
117_V	416_Q	1.312	1.00
67_G	70_D	1.304	1.00
79_Y	83_Y	1.300	1.00
421_A	425_G	1.294	1.00
454_V	458_V	1.292	1.00
151_A	366_F	1.285	1.00
23_Y	354_G	1.279	1.00
341_V	345_A	1.277	1.00
110_L	409_F	1.273	1.00
102_G	107_S	1.263	1.00
149_A	153_F	1.259	1.00
104_R	397_A	1.257	1.00
404_T	465_A	1.257	1.00
206_A	210_E	1.248	1.00
345_A	350_E	1.246	1.00
100_M	104_R	1.246	1.00
81_L	85_Q	1.239	1.00
402_R	466_P	1.236	1.00
25_A	29_L	1.234	1.00
67_G	73_L	1.228	1.00
201_G	205_G	1.222	1.00
81_L	395_A	1.215	1.00
7_V	176_L	1.213	1.00
452_L	456_L	1.211	1.00
138_V	147_Y	1.207	1.00
451_P	454_V	1.206	1.00
173_T	322_D	1.201	1.00
211_F	215_G	1.195	1.00
155_T	362_A	1.194	1.00
96_T	330_S	1.190	1.00
152_G	366_F	1.188	1.00
220_S	223_W	1.187	1.00
367_G	371_L	1.180	1.00
332_F	337_Y	1.175	1.00
152_G	370_L	1.171	1.00
4_A	8_G	1.170	1.00
3_V	176_L	1.162	1.00
349_R	353_L	1.161	1.00
116_G	120_F	1.157	1.00
121_W	386_G	1.155	1.00
83_Y	255_K	1.154	1.00
405_K	409_F	1.153	1.00
41_T	323_S	1.153	1.00
205_G	209_A	1.152	1.00
35_L	260_I	1.151	1.00
333_T	354_G	1.146	1.00
91_A	251_K	1.146	1.00
112_G	340_F	1.145	1.00
179_V	183_G	1.140	1.00
133_A	154_I	1.139	1.00
107_S	405_K	1.138	1.00
174_D	322_D	1.132	1.00
25_A	167_M	1.131	1.00
448_V	451_P	1.129	1.00
354_G	358_V	1.125	1.00
353_L	357_G	1.123	1.00
130_Q	155_T	1.123	1.00
4_A	176_L	1.122	1.00
404_T	460_V	1.117	1.00
111_R	335_D	1.113	1.00
3_V	7_V	1.111	1.00
418_F	456_L	1.108	1.00
195_E	282_V	1.107	1.00
31_T	35_L	1.099	1.00
183_G	187_V	1.096	1.00
55_A	62_W	1.095	1.00
411_G	453_G	1.093	1.00
102_G	339_P	1.090	1.00
288_D	291_N	1.085	1.00
113_L	412_V	1.080	1.00
333_T	353_L	1.078	1.00
114_V	412_V	1.078	1.00
37_T	323_S	1.070	1.00
39_F	264_L	1.063	1.00
446_Q	450_L	1.061	1.00
15_T	21_D	1.056	1.00
145_V	150_G	1.054	1.00
379_V	383_A	1.053	1.00
69_M	73_L	1.052	1.00
5_L	8_G	1.047	1.00
286_L	289_G	1.045	1.00
110_L	408_M	1.044	1.00
406_A	463_V	1.044	1.00
393_P	412_V	1.037	1.00
406_A	460_V	1.034	1.00
375_S	378_E	1.034	1.00
187_V	305_F	1.032	1.00
347_A	350_E	1.032	1.00
161_Y	322_D	1.030	1.00
69_M	72_V	1.029	1.00
5_L	9_L	1.029	1.00
297_L	309_V	1.028	1.00
126_V	365_A	1.024	1.00
357_G	360_A	1.019	1.00
148_W	152_G	1.018	1.00
177_Q	322_D	1.008	1.00
456_L	459_G	1.008	1.00
158_M	322_D	1.004	1.00
67_G	71_G	1.001	1.00
119_I	332_F	1.000	1.00
109_G	113_L	0.999	1.00
396_L	403_T	0.998	1.00
101_L	110_L	0.998	1.00
278_W	282_V	0.991	1.00
37_T	40_A	0.989	1.00
389_Q	453_G	0.987	1.00
239_P	327_S	0.986	1.00
57_A	289_G	0.969	1.00
127_M	368_G	0.967	1.00
161_Y	318_M	0.966	1.00
326_L	329_S	0.965	1.00
130_Q	151_A	0.964	1.00
337_Y	341_V	0.964	1.00
163_A	359_A	0.963	1.00
411_G	415_T	0.962	1.00
173_T	177_Q	0.959	1.00
141_T	145_V	0.957	1.00
196_I	199_T	0.954	1.00
68_L	72_V	0.953	1.00
23_Y	330_S	0.952	1.00
294_P	297_L	0.952	1.00
403_T	461_S	0.950	1.00
7_V	11_A	0.943	1.00
66_M	70_D	0.942	1.00
105_F	397_A	0.940	1.00
117_V	412_V	0.940	1.00
382_T	423_V	0.938	1.00
33_V	171_A	0.937	1.00
31_T	256_R	0.936	1.00
332_F	361_F	0.934	1.00
191_W	195_E	0.931	1.00
92_N	103_D	0.930	1.00
54_I	58_N	0.927	1.00
187_V	191_W	0.924	1.00
402_R	467_S	0.920	1.00
6_A	9_L	0.912	1.00
204_A	209_A	0.912	1.00
20_E	93_G	0.911	1.00
248_A	254_L	0.908	1.00
397_A	408_M	0.908	1.00
3_V	6_A	0.907	1.00
297_L	306_A	0.905	1.00
109_G	405_K	0.904	1.00
101_L	114_V	0.903	1.00
174_D	323_S	0.898	1.00
145_V	153_F	0.897	1.00
396_L	458_V	0.896	1.00
239_P	243_Q	0.896	1.00
450_L	453_G	0.893	1.00
393_P	453_G	0.887	1.00
360_A	364_A	0.885	1.00
452_L	455_V	0.882	1.00
119_I	328_G	0.882	1.00
142_G	146_P	0.882	1.00
279_A	296_L	0.881	1.00
71_G	74_F	0.879	1.00
403_T	407_G	0.879	1.00
453_G	457_T	0.874	1.00
41_T	174_D	0.872	1.00
37_T	244_R	0.871	1.00
413_L	417_A	0.869	1.00
204_A	210_E	0.869	1.00
363_V	366_F	0.866	1.00
392_P	454_V	0.864	1.00
454_V	457_T	0.863	1.00
45_A	317_M	0.862	1.00
345_A	353_L	0.859	1.00
25_A	247_V	0.858	1.00
67_G	72_V	0.856	1.00
415_T	419_Y	0.856	1.00
259_A	263_L	0.855	1.00
172_W	175_T	0.855	1.00
188_A	192_V	0.852	1.00
263_L	267_L	0.850	1.00
113_L	413_L	0.849	1.00
138_V	142_G	0.847	1.00
189_F	271_P	0.846	1.00
4_A	11_A	0.846	1.00
329_S	333_T	0.842	1.00
5_L	160_V	0.840	1.00
60_P	277_A	0.835	1.00
77_L	83_Y	0.835	1.00
284_L	287_P	0.834	1.00
421_A	424_F	0.830	1.00
406_A	465_A	0.827	1.00
82_G	85_Q	0.825	1.00
356_V	359_A	0.825	1.00
83_Y	251_K	0.823	1.00
36_F	178_G	0.823	1.00
380_G	384_F	0.821	1.00
196_I	201_G	0.821	1.00
211_F	216_G	0.821	1.00
68_L	71_G	0.817	1.00
177_Q	315_A	0.817	1.00
212_R	216_G	0.816	1.00
459_G	462_A	0.816	1.00
221_P	224_M	0.816	1.00
438_S	441_F	0.815	1.00
66_M	72_V	0.812	1.00
409_F	413_L	0.812	1.00
11_A	15_T	0.812	1.00
30_G	253_T	0.811	1.00
55_A	277_A	0.811	1.00
358_V	362_A	0.804	1.00
319_S	322_D	0.804	1.00
418_F	422_T	0.804	1.00
151_A	369_S	0.802	1.00
192_V	195_E	0.801	1.00
135_E	138_V	0.800	1.00
445_A	449_G	0.800	1.00
147_Y	151_A	0.798	1.00
422_T	448_V	0.796	1.00
201_G	204_A	0.792	1.00
195_E	300_Y	0.792	1.00
465_A	468_D	0.792	1.00
4_A	9_L	0.792	1.00
350_E	354_G	0.791	1.00
418_F	421_A	0.791	1.00
8_G	12_Y	0.785	1.00
106_G	468_D	0.784	1.00
188_A	293_V	0.783	1.00
440_Y	443_W	0.783	1.00
404_T	466_P	0.783	1.00
161_Y	177_Q	0.783	1.00
414_G	460_V	0.781	1.00
200_T	205_G	0.780	1.00
291_N	295_I	0.778	1.00
337_Y	340_F	0.778	1.00
191_W	194_A	0.777	1.00
79_Y	82_G	0.776	1.00
301_T	305_F	0.776	1.00
150_G	154_I	0.775	1.00
67_G	74_F	0.775	1.00
37_T	41_T	0.774	1.00
31_T	260_I	0.773	1.00
112_G	336_I	0.771	1.00
304_W	308_L	0.771	1.00
459_G	463_V	0.769	1.00
14_V	168_R	0.768	1.00
40_A	244_R	0.767	1.00
61_E	64_L	0.767	1.00
196_I	281_G	0.762	1.00
416_Q	420_L	0.762	1.00
458_V	461_S	0.762	1.00
114_V	390_L	0.760	1.00
78_W	85_Q	0.758	1.00
37_T	171_A	0.757	1.00
280_N	292_I	0.755	1.00
449_G	453_G	0.755	1.00
275_M	296_L	0.754	1.00
15_T	351_D	0.753	1.00
98_G	114_V	0.750	1.00
99_E	103_D	0.749	1.00
206_A	281_G	0.749	1.00
70_D	73_L	0.748	1.00
417_A	420_L	0.746	1.00
104_R	400_W	0.746	1.00
14_V	17_R	0.745	1.00
400_W	461_S	0.742	1.00
161_Y	319_S	0.740	1.00
17_R	21_D	0.739	1.00
170_V	173_T	0.739	1.00
403_T	411_G	0.737	1.00
329_S	357_G	0.734	0.99
450_L	454_V	0.734	0.99
463_V	466_P	0.733	0.99
80_V	83_Y	0.732	0.99
42_L	384_F	0.731	0.99
415_T	453_G	0.731	0.99
400_W	404_T	0.731	0.99
182_L	186_W	0.729	0.99
22_Y	358_V	0.728	0.99
105_F	457_T	0.727	0.99
177_Q	318_M	0.727	0.99
112_G	115_A	0.725	0.99
77_L	82_G	0.723	0.99
9_L	164_I	0.720	0.99
9_L	13_R	0.719	0.99
44_S	125_Y	0.719	0.99
142_G	145_V	0.715	0.99
444_F	448_V	0.715	0.99
407_G	410_A	0.714	0.99
233_V	391_A	0.711	0.99
248_A	253_T	0.709	0.99
29_L	34_L	0.708	0.99
329_S	358_V	0.707	0.99
129_Q	320_S	0.707	0.99
464_T	467_S	0.706	0.99
296_L	300_Y	0.706	0.99
410_A	413_L	0.706	0.99
9_L	12_Y	0.705	0.99
134_G	147_Y	0.705	0.99
213_A	217_G	0.701	0.99
96_T	335_D	0.699	0.99
185_T	272_A	0.699	0.99
68_L	73_L	0.699	0.99
131_I	135_E	0.698	0.99
273_F	277_A	0.698	0.99
177_Q	319_S	0.697	0.99
366_F	370_L	0.696	0.99
109_G	112_G	0.696	0.99
170_V	323_S	0.694	0.99
240_Q	243_Q	0.694	0.99
366_F	369_S	0.694	0.99
455_V	458_V	0.692	0.99
341_V	344_D	0.692	0.99
332_F	353_L	0.685	0.99
320_S	324_M	0.684	0.99
400_W	407_G	0.683	0.99
177_Q	320_S	0.682	0.99
441_F	444_F	0.682	0.99
19_A	23_Y	0.680	0.99
275_M	293_V	0.680	0.99
367_G	370_L	0.679	0.99
440_Y	448_V	0.679	0.99
48_F	185_T	0.678	0.99
171_A	174_D	0.676	0.99
324_M	327_S	0.673	0.99
95_V	99_E	0.671	0.99
133_A	317_M	0.670	0.99
112_G	116_G	0.670	0.99
74_F	78_W	0.670	0.99
337_Y	343_A	0.667	0.99
283_G	299_E	0.666	0.99
194_A	199_T	0.666	0.99
22_Y	355_R	0.662	0.99
32_G	36_F	0.662	0.99
54_I	57_A	0.658	0.99
228_A	232_A	0.656	0.99
107_S	110_L	0.656	0.99
44_S	48_F	0.654	0.99
460_V	463_V	0.652	0.99
40_A	178_G	0.649	0.99
10_V	13_R	0.649	0.99
3_V	9_L	0.649	0.99
333_T	350_E	0.648	0.99
152_G	363_V	0.648	0.99
4_A	12_Y	0.647	0.99
286_L	295_I	0.647	0.99
441_F	448_V	0.646	0.99
447_V	451_P	0.644	0.99
13_R	17_R	0.643	0.99
12_Y	164_I	0.642	0.99
18_D	26_G	0.642	0.99
159_V	359_A	0.641	0.99
56_Y	292_I	0.641	0.99
388_A	392_P	0.641	0.99
129_Q	321_S	0.640	0.99
47_T	269_F	0.640	0.99
162_V	322_D	0.639	0.99
221_P	225_L	0.639	0.99
333_T	337_Y	0.639	0.99
418_F	449_G	0.638	0.99
8_G	13_R	0.638	0.99
107_S	339_P	0.637	0.99
338_R	347_A	0.634	0.99
396_L	400_W	0.633	0.98
262_P	266_V	0.633	0.98
404_T	408_M	0.631	0.98
406_A	409_F	0.631	0.98
30_G	33_V	0.631	0.98
118_S	331_Y	0.630	0.98
338_R	343_A	0.628	0.98
40_A	177_Q	0.627	0.98
125_Y	324_M	0.625	0.98
415_T	418_F	0.624	0.98
10_V	14_V	0.623	0.98
408_M	415_T	0.623	0.98
298_S	306_A	0.622	0.98
291_N	294_P	0.622	0.98
110_L	405_K	0.619	0.98
35_L	39_F	0.619	0.98
234_G	238_F	0.618	0.98
81_L	84_R	0.618	0.98
249_D	252_R	0.617	0.98
56_Y	286_L	0.617	0.98
195_E	199_T	0.617	0.98
125_Y	238_F	0.616	0.98
447_V	450_L	0.613	0.98
325_L	358_V	0.612	0.98
286_L	291_N	0.611	0.98
48_F	309_V	0.611	0.98
168_R	172_W	0.609	0.98
189_F	274_L	0.609	0.98
402_R	406_A	0.608	0.98
214_L	218_A	0.608	0.98
167_M	171_A	0.608	0.98
196_I	203_L	0.608	0.98
126_V	321_S	0.606	0.98
256_R	260_I	0.605	0.98
135_E	290_E	0.604	0.98
377_L	381_S	0.604	0.98
152_G	155_T	0.603	0.98
105_F	396_L	0.603	0.98
186_W	189_F	0.603	0.98
283_G	295_I	0.602	0.98
105_F	408_M	0.601	0.98
245_F	258_F	0.600	0.98
443_W	447_V	0.598	0.98
19_A	350_E	0.597	0.98
193_A	198_G	0.596	0.98
199_T	204_A	0.596	0.98
107_S	111_R	0.596	0.98
462_A	465_A	0.596	0.98
223_W	226_S	0.595	0.98
32_G	175_T	0.595	0.98
161_Y	169_G	0.593	0.98
84_R	399_Y	0.593	0.98
193_A	274_L	0.592	0.98
203_L	208_P	0.590	0.98
225_L	228_A	0.589	0.98
443_W	446_Q	0.589	0.98
283_G	286_L	0.588	0.98
155_T	369_S	0.586	0.98
282_V	296_L	0.586	0.98
333_T	357_G	0.585	0.97
420_L	424_F	0.585	0.97
402_R	405_K	0.583	0.97
135_E	139_G	0.582	0.97
60_P	63_I	0.581	0.97
294_P	313_A	0.581	0.97
442_G	446_Q	0.580	0.97
111_R	339_P	0.580	0.97
187_V	190_V	0.579	0.97
106_G	110_L	0.579	0.97
446_Q	453_G	0.579	0.97
230_G	238_F	0.579	0.97
457_T	460_V	0.579	0.97
174_D	319_S	0.579	0.97
37_T	174_D	0.577	0.97
303_G	306_A	0.576	0.97
124_P	383_A	0.576	0.97
54_I	62_W	0.576	0.97
318_M	322_D	0.576	0.97
21_D	168_R	0.576	0.97
215_G	218_A	0.573	0.97
139_G	291_N	0.570	0.97
364_A	367_G	0.570	0.97
46_F	380_G	0.569	0.97
243_Q	327_S	0.569	0.97
80_V	84_R	0.568	0.97
39_F	178_G	0.567	0.97
77_L	85_Q	0.566	0.97
33_V	172_W	0.565	0.97
68_L	74_F	0.564	0.97
20_E	347_A	0.564	0.97
69_M	266_V	0.564	0.97
123_F	368_G	0.564	0.97
355_R	358_V	0.563	0.97
110_L	114_V	0.563	0.97
5_L	12_Y	0.562	0.97
302_P	305_F	0.562	0.97
130_Q	169_G	0.561	0.97
19_A	22_Y	0.561	0.97
174_D	177_Q	0.560	0.97
97_L	394_V	0.560	0.97
159_V	163_A	0.558	0.97
161_Y	165_S	0.556	0.97
41_T	244_R	0.556	0.97
131_I	147_Y	0.555	0.97
444_F	449_G	0.555	0.97
60_P	64_L	0.554	0.97
408_M	411_G	0.552	0.96
137_L	150_G	0.552	0.96
29_L	247_V	0.551	0.96
138_V	146_P	0.550	0.96
137_L	141_T	0.550	0.96
244_R	323_S	0.547	0.96
101_L	393_P	0.547	0.96
412_V	415_T	0.546	0.96
170_V	326_L	0.545	0.96
423_V	445_A	0.545	0.96
39_F	268_L	0.545	0.96
151_A	370_L	0.545	0.96
414_G	417_A	0.543	0.96
193_A	197_A	0.543	0.96
256_R	259_A	0.542	0.96
365_A	369_S	0.542	0.96
234_G	384_F	0.542	0.96
3_V	11_A	0.541	0.96
196_I	200_T	0.539	0.96
374_G	378_E	0.539	0.96
410_A	459_G	0.536	0.96
123_F	364_A	0.535	0.96
34_L	37_T	0.535	0.96
12_Y	15_T	0.535	0.96
66_M	73_L	0.534	0.96
115_A	331_Y	0.534	0.96
125_Y	240_Q	0.533	0.96
53_N	289_G	0.533	0.96
301_T	309_V	0.532	0.96
107_S	112_G	0.531	0.96
193_A	199_T	0.531	0.96
151_A	155_T	0.530	0.96
216_G	219_Y	0.529	0.95
11_A	172_W	0.528	0.95
439_S	444_F	0.528	0.95
188_A	309_V	0.528	0.95
268_L	272_A	0.527	0.95
170_V	244_R	0.526	0.95
219_Y	222_Q	0.526	0.95
30_G	34_L	0.526	0.95
98_G	118_S	0.522	0.95
425_G	428_V	0.522	0.95
209_A	280_N	0.522	0.95
392_P	457_T	0.521	0.95
42_L	235_V	0.521	0.95
201_G	206_A	0.520	0.95
122_L	383_A	0.520	0.95
129_Q	132_G	0.520	0.95
381_S	385_G	0.520	0.95
346_T	352_T	0.520	0.95
192_V	300_Y	0.519	0.95
237_M	394_V	0.517	0.95
51_G	55_A	0.517	0.95
66_M	69_M	0.516	0.95
111_R	115_A	0.516	0.95
4_A	7_V	0.515	0.95
39_F	261_W	0.515	0.95
134_G	150_G	0.514	0.95
112_G	339_P	0.514	0.95
43_L	261_W	0.514	0.95
44_S	129_Q	0.513	0.95
391_A	395_A	0.512	0.95
265_V	269_F	0.512	0.95
69_M	224_M	0.512	0.95
403_T	408_M	0.512	0.95
50_A	125_Y	0.511	0.95
203_L	209_A	0.510	0.95
259_A	262_P	0.510	0.95
95_V	334_R	0.510	0.95
301_T	304_W	0.510	0.95
267_L	271_P	0.509	0.94
289_G	292_I	0.508	0.94
294_P	309_V	0.508	0.94
359_A	363_V	0.507	0.94
444_F	447_V	0.506	0.94
212_R	217_G	0.506	0.94
407_G	453_G	0.506	0.94
234_G	239_P	0.505	0.94
251_K	255_K	0.505	0.94
407_G	456_L	0.505	0.94
230_G	234_G	0.504	0.94
125_Y	129_Q	0.504	0.94
94_Y	99_E	0.502	0.94
428_V	440_Y	0.502	0.94
46_F	384_F	0.502	0.94
39_F	43_L	0.502	0.94
98_G	115_A	0.502	0.94
42_L	380_G	0.500	0.94

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2xq2A	2	0.9191	100	0.243	Contact Map
3dh4A	3	0.8963	100	0.26	Contact Map
3giaA	1	0.8755	99.2	0.854	Contact Map
3l1lA	2	0.8444	99.2	0.854	Contact Map
4wgvA	2	0.7676	98.9	0.874	Contact Map
4djkA	2	0.8361	98.7	0.88	Contact Map
2jlnA	1	0.8402	98.5	0.889	Contact Map
2a65A	2	0.888	94.2	0.936	Contact Map
4us3A	1	0.8195	93.5	0.938	Contact Map
4xp4A	1	0.9046	93.2	0.938	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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