GREMLIN Database
PYRG - CTP synthase
UniProt: Q9HP32 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 553 (522)
Sequences: 2967 (1258)
Seq/√Len: 55.1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
457_L529_G4.6971.00
376_Q380_E4.6501.00
304_A354_A4.1881.00
302_D334_N4.1081.00
302_D336_L3.8871.00
300_E334_N3.7791.00
375_I394_L3.7681.00
408_G420_Y3.7031.00
382_D505_P3.6081.00
175_D178_D3.4651.00
303_I356_G3.4291.00
336_L354_A3.3261.00
35_L269_V3.3131.00
454_A498_I3.2261.00
443_A464_T3.1511.00
375_I507_F2.9791.00
375_I385_F2.9701.00
261_E266_D2.8791.00
180_L216_I2.8411.00
453_L456_D2.7961.00
373_D376_Q2.7761.00
479_D483_A2.7731.00
344_H347_H2.6951.00
452_T487_T2.6751.00
394_L397_V2.6531.00
357_I378_A2.6421.00
399_Y403_V2.6321.00
326_S333_V2.6101.00
331_V535_L2.5851.00
336_L353_D2.5411.00
418_T421_P2.5151.00
406_M480_D2.4851.00
382_D503_D2.4631.00
251_E255_H2.4511.00
31_T218_V2.4041.00
487_T502_D2.4041.00
385_F395_A2.3901.00
455_H461_T2.3831.00
44_F146_V2.3801.00
242_D271_E2.3561.00
134_K173_E2.3461.00
498_I512_F2.3331.00
206_E209_S2.3221.00
181_F212_L2.3211.00
216_I265_L2.2871.00
190_S222_E2.2781.00
450_P455_H2.2561.00
107_Q111_E2.2541.00
91_D522_R2.2471.00
406_M420_Y2.2371.00
454_A489_S2.1991.00
227_P231_E2.1921.00
404_L481_L2.1911.00
131_D135_R2.1771.00
329_A532_D2.1621.00
411_S414_I2.1191.00
299_G331_V2.1141.00
408_G419_E2.0711.00
420_Y477_Y2.0611.00
453_L508_F2.0411.00
109_V129_V1.9681.00
304_A338_V1.9611.00
231_E241_M1.9461.00
319_H337_W1.9281.00
412_A421_P1.9201.00
452_T489_S1.9201.00
258_L290_R1.9141.00
74_D443_A1.9051.00
506_F530_L1.9001.00
410_H415_D1.8800.99
449_E482_T1.8760.99
170_F174_Q1.8640.99
108_D132_D1.8420.99
481_L486_L1.8400.99
359_V385_F1.8360.99
66_Q121_K1.8300.99
298_T330_G1.8110.99
96_S104_K1.8080.99
368_T394_L1.8070.99
74_D93_D1.7990.99
395_A507_F1.7890.99
457_L508_F1.7730.99
138_R170_F1.7680.99
532_D536_E1.7650.99
300_E332_E1.7630.99
396_V422_V1.7620.99
473_V481_L1.7480.99
479_D482_T1.7240.99
291_D295_R1.7200.99
406_M477_Y1.7050.99
40_S91_D1.6940.99
132_D135_R1.6720.99
450_P461_T1.6720.99
15_F141_A1.6710.99
295_R330_G1.6190.98
369_A372_I1.6160.98
109_V118_Y1.5970.98
480_D483_A1.5730.98
385_F394_L1.5660.98
343_M347_H1.5590.98
299_G535_L1.5560.98
41_N286_S1.5520.98
390_L414_I1.5510.98
187_V225_L1.5420.98
382_D504_H1.5420.98
185_T200_T1.5400.98
386_L530_L1.5380.98
506_F529_G1.5320.98
358_V530_L1.5180.98
454_A508_F1.5150.98
423_I473_V1.5150.98
404_L480_D1.5090.98
25_G192_N1.5050.98
40_S92_E1.4890.97
356_G530_L1.4880.97
368_T414_I1.4860.97
146_V273_F1.4780.97
396_V499_V1.4690.97
473_V478_I1.4660.97
14_K178_D1.4600.97
135_R139_E1.4510.97
449_E487_T1.4480.97
172_H238_D1.4400.97
446_T512_F1.4370.97
408_G415_D1.4360.97
243_A268_Y1.4320.97
164_L210_I1.4300.97
32_A148_L1.4290.97
443_A517_R1.4270.97
183_H203_S1.4120.96
406_M419_E1.4120.96
446_T490_G1.4090.96
448_I454_A1.4030.96
112_R117_D1.4020.96
368_T390_L1.4010.96
392_F473_V1.4010.96
108_D136_R1.3980.96
517_R524_S1.3900.96
343_M350_R1.3860.96
399_Y484_D1.3860.96
457_L506_F1.3830.96
177_E274_D1.3750.96
475_P478_I1.3590.95
246_S263_E1.3520.95
48_A90_L1.3520.95
445_E464_T1.3490.95
74_D517_R1.3450.95
180_L272_Q1.3450.95
247_N260_V1.3430.95
264_G267_Q1.3310.95
302_D354_A1.3310.95
398_E402_N1.3280.95
339_D342_K1.3270.95
47_T98_H1.3270.95
392_F499_V1.3260.95
305_L318_I1.3240.95
445_E462_S1.3130.94
245_F268_Y1.3100.94
217_L233_I1.3100.94
343_M374_A1.3060.94
396_V473_V1.3040.94
35_L182_T1.2900.94
375_I398_E1.2790.94
328_E523_A1.2750.94
55_L129_V1.2720.94
151_V167_L1.2700.93
429_Q432_L1.2680.93
18_V148_L1.2660.93
49_V149_V1.2640.93
395_A509_G1.2620.93
356_G534_V1.2560.93
250_V259_T1.2540.93
138_R174_Q1.2520.93
410_H418_T1.2440.93
502_D505_P1.2350.92
167_L181_F1.2340.92
302_D353_D1.2330.92
205_K209_S1.2300.92
55_L102_T1.2280.92
137_V170_F1.2270.92
93_D519_R1.2240.92
486_L499_V1.2180.92
221_C246_S1.2100.92
303_I534_V1.2090.92
104_K136_R1.2030.91
376_Q402_N1.1990.91
119_L435_L1.1980.91
37_R40_S1.1960.91
51_I149_V1.1900.91
173_E181_F1.1870.91
424_D429_Q1.1810.91
475_P496_M1.1780.91
171_S179_I1.1760.90
195_Q226_D1.1720.90
215_D272_Q1.1690.90
102_T129_V1.1610.90
451_G456_D1.1550.90
404_L484_D1.1550.90
31_T184_V1.1530.90
16_V180_L1.1490.89
447_A462_S1.1450.89
451_G455_H1.1440.89
448_I490_G1.1430.89
357_I383_V1.1410.89
226_D229_V1.1390.89
349_R352_A1.1350.89
453_L506_F1.1330.89
448_I452_T1.1330.89
106_Y125_I1.1300.89
480_D484_D1.1270.89
415_D418_T1.1210.88
412_A418_T1.1200.88
395_A499_V1.1150.88
146_V275_M1.1130.88
385_F507_F1.1120.88
51_I59_A1.1010.87
180_L269_V1.0950.87
268_Y272_Q1.0940.87
108_D112_R1.0880.87
358_V388_L1.0880.87
306_V340_S1.0860.87
221_C248_P1.0850.87
267_Q271_E1.0820.86
399_Y486_L1.0770.86
30_I256_V1.0750.86
258_L293_V1.0730.86
407_T420_Y1.0730.86
501_H504_H1.0720.86
14_K273_F1.0690.86
359_V395_A1.0690.86
322_L333_V1.0640.85
91_D519_R1.0640.85
227_P241_M1.0640.85
31_T247_N1.0620.85
208_R238_D1.0600.85
297_R330_G1.0520.85
427_P494_N1.0520.85
51_I137_V1.0500.85
37_R41_N1.0460.84
457_L530_L1.0440.84
51_I85_N1.0420.84
348_E381_H1.0360.84
255_H293_V1.0290.83
171_S181_F1.0270.83
386_L508_F1.0240.83
369_A401_R1.0220.83
464_T517_R1.0220.83
47_T147_C1.0160.83
396_V481_L1.0160.83
344_H373_D1.0150.83
31_T260_V1.0110.82
345_D373_D1.0100.82
343_M373_D1.0100.82
488_F496_M1.0080.82
208_R213_Q1.0050.82
400_A481_L1.0030.82
336_L350_R0.9970.82
44_F277_E0.9970.82
412_A424_D0.9970.82
261_E284_Q0.9900.81
292_L327_L0.9840.81
252_D293_V0.9780.80
529_G532_D0.9780.80
448_I455_H0.9780.80
358_V371_K0.9750.80
182_T269_V0.9740.80
420_Y480_D0.9730.80
19_T183_H0.9720.80
164_L212_L0.9720.80
351_I354_A0.9720.80
425_L429_Q0.9720.80
396_V486_L0.9710.80
171_S176_D0.9710.80
358_V378_A0.9710.80
270_M277_E0.9700.80
312_E337_W0.9690.80
338_V354_A0.9640.79
379_R398_E0.9630.79
100_V136_R0.9620.79
318_I388_L0.9580.79
204_V214_P0.9580.79
424_D427_P0.9560.79
125_I129_V0.9560.79
325_A528_V0.9510.78
290_R294_T0.9480.78
482_T488_F0.9480.78
233_I244_V0.9470.78
454_A510_T0.9360.77
318_I361_G0.9340.77
174_Q178_D0.9270.77
132_D136_R0.9270.77
455_H459_G0.9230.76
111_E434_D0.9200.76
155_V164_L0.9200.76
176_D215_D0.9200.76
40_S90_L0.9190.76
304_A336_L0.9150.76
146_V270_M0.9140.76
106_Y162_P0.9100.75
219_G233_I0.9070.75
392_F510_T0.9040.75
224_R248_P0.9030.75
375_I397_V0.8970.74
305_L319_H0.8960.74
44_F270_M0.8930.74
200_T233_I0.8900.74
165_E168_R0.8900.74
501_H507_F0.8890.73
390_L411_S0.8890.73
266_D284_Q0.8860.73
63_N66_Q0.8850.73
141_A147_C0.8840.73
115_S434_D0.8830.73
325_A329_A0.8820.73
92_E519_R0.8770.72
326_S531_L0.8760.72
262_E290_R0.8740.72
59_A85_N0.8700.72
426_L429_Q0.8680.72
242_D268_Y0.8650.71
119_L439_M0.8620.71
271_E274_D0.8610.71
313_D318_I0.8610.71
42_A266_D0.8610.71
97_D139_E0.8590.71
445_E492_A0.8580.71
447_A461_T0.8580.71
37_R521_T0.8570.71
445_E491_E0.8550.71
49_V59_A0.8540.70
329_A531_L0.8510.70
463_C524_S0.8450.70
259_T262_E0.8370.69
94_M98_H0.8370.69
105_V136_R0.8370.69
45_D143_G0.8350.69
109_V164_L0.8340.69
138_R173_E0.8330.69
188_P200_T0.8310.68
316_M323_K0.8300.68
224_R246_S0.8300.68
41_N284_Q0.8290.68
189_Y192_N0.8290.68
399_Y501_H0.8290.68
48_A98_H0.8270.68
250_V256_V0.8270.68
26_L31_T0.8240.68
299_G538_A0.8240.68
265_L269_V0.8220.67
218_V247_N0.8200.67
216_I268_Y0.8190.67
55_L109_V0.8180.67
190_S223_D0.8170.67
195_Q229_V0.8160.67
100_V313_D0.8160.67
404_L486_L0.8110.66
171_S238_D0.8090.66
167_L179_I0.8050.66
488_F499_V0.8040.66
221_C225_L0.8020.66
498_I510_T0.7990.65
465_E524_S0.7990.65
105_V132_D0.7980.65
51_I100_V0.7930.65
452_T490_G0.7920.65
77_G96_S0.7900.64
424_D430_Y0.7900.64
185_T188_P0.7860.64
372_I394_L0.7860.64
420_Y476_E0.7850.64
230_R263_E0.7840.64
352_A377_H0.7830.64
477_Y480_D0.7820.64
355_D538_A0.7820.64
377_H381_H0.7820.64
453_L503_D0.7810.63
140_A147_C0.7800.63
382_D502_D0.7790.63
49_V148_L0.7730.63
343_M348_E0.7710.62
347_H351_I0.7700.62
44_F145_D0.7690.62
397_V410_H0.7690.62
453_L457_L0.7680.62
321_A325_A0.7680.62
299_G330_G0.7660.62
177_E272_Q0.7660.62
375_I395_A0.7630.62
467_H497_E0.7610.61
141_A144_S0.7600.61
267_Q277_E0.7550.61
74_D464_T0.7540.61
357_I530_L0.7500.60
356_G386_L0.7480.60
325_A333_V0.7480.60
243_A272_Q0.7450.60
301_V534_V0.7450.60
108_D111_E0.7430.60
288_E521_T0.7420.60
529_G533_A0.7420.60
352_A381_H0.7390.59
44_F276_V0.7370.59
49_V98_H0.7360.59
230_R246_S0.7350.59
358_V395_A0.7320.58
347_H350_R0.7310.58
247_N263_E0.7300.58
217_L239_V0.7280.58
478_I496_M0.7280.58
454_A509_G0.7270.58
371_K394_L0.7270.58
73_L79_V0.7270.58
407_T419_E0.7260.58
505_P537_R0.7250.58
304_A355_D0.7230.58
347_H373_D0.7200.57
446_T454_A0.7180.57
130_T169_Q0.7170.57
499_V507_F0.7170.57
302_D355_D0.7170.57
93_D443_A0.7150.57
325_A531_L0.7150.57
428_E439_M0.7140.57
297_R332_E0.7140.57
523_A528_V0.7130.56
499_V509_G0.7130.56
26_L184_V0.7130.56
174_Q179_I0.7130.56
125_I158_I0.7100.56
126_I130_T0.7090.56
348_E352_A0.7080.56
195_Q223_D0.7080.56
62_M70_V0.7050.56
73_L77_G0.7040.56
42_A270_M0.7030.55
388_L510_T0.7030.55
74_D516_Y0.7020.55
134_K169_Q0.7020.55
378_A385_F0.7010.55
216_I263_E0.7010.55
369_A410_H0.6990.55
261_E283_A0.6980.55
187_V246_S0.6970.55
451_G487_T0.6970.55
338_V343_M0.6970.55
240_P272_Q0.6960.55
404_L482_T0.6940.54
205_K208_R0.6940.54
59_A189_Y0.6930.54
19_T203_S0.6930.54
312_E319_H0.6910.54
124_Q159_E0.6900.54
36_G148_L0.6890.54
528_V532_D0.6880.54
71_Y93_D0.6860.54
447_A491_E0.6840.53
288_E291_D0.6840.53
353_D383_V0.6840.53
325_A328_E0.6810.53
318_I429_Q0.6770.53
171_S215_D0.6770.53
508_F526_P0.6760.53
18_V48_A0.6750.52
99_N119_L0.6730.52
225_L229_V0.6720.52
306_V359_V0.6710.52
111_E115_S0.6710.52
341_E366_R0.6700.52
192_N249_D0.6700.52
449_E452_T0.6690.52
322_L335_V0.6680.52
490_G498_I0.6670.52
65_Y71_Y0.6670.52
447_A493_G0.6670.52
49_V100_V0.6660.51
322_L358_V0.6660.51
47_T144_S0.6650.51
219_G439_M0.6650.51
489_S501_H0.6630.51
44_F275_M0.6610.51
399_Y481_L0.6610.51
26_L186_L0.6610.51
256_V263_E0.6600.51
191_K234_A0.6590.51
266_D270_M0.6590.51
318_I360_A0.6580.51
104_K108_D0.6580.51
374_A378_A0.6570.50
77_G104_K0.6570.50
71_Y519_R0.6570.50
216_I243_A0.6550.50
376_Q381_H0.6530.50
57_V62_M0.6500.50
25_G247_N0.6500.50
446_T498_I0.6490.50
179_I212_L0.6490.50
402_N407_T0.6490.50
473_V498_I0.6480.50
455_H460_A0.6460.49
270_M275_M0.6450.49
292_L521_T0.6440.49
478_I488_F0.6440.49
404_L408_G0.6440.49
392_F512_F0.6410.49
35_L265_L0.6410.49
131_D231_E0.6400.49
46_V479_D0.6400.49
519_R522_R0.6390.49
125_I162_P0.6390.49
255_H258_L0.6390.49
372_I375_I0.6370.48
151_V164_L0.6360.48
146_V277_E0.6350.48
390_L394_L0.6340.48
55_L125_I0.6310.48
368_T397_V0.6310.48
473_V496_M0.6310.48
25_G197_T0.6300.48
358_V510_T0.6300.48
311_L314_A0.6290.47
342_K350_R0.6280.47
368_T410_H0.6280.47
399_Y404_L0.6270.47
15_F138_R0.6260.47
329_A535_L0.6250.47
414_I418_T0.6220.47
255_H294_T0.6220.47
95_T98_H0.6200.47
110_I256_V0.6200.47
71_Y90_L0.6190.46
112_R135_R0.6190.46
13_S147_C0.6170.46
44_F260_V0.6170.46
35_L218_V0.6160.46
55_L337_W0.6150.46
91_D521_T0.6150.46
388_L527_F0.6140.46
372_I376_Q0.6130.46
386_L529_G0.6130.46
248_P259_T0.6120.46
328_E528_V0.6110.46
512_F524_S0.6110.46
238_D243_A0.6110.46
162_P202_H0.6100.45
17_F167_L0.6100.45
303_I531_L0.6100.45
115_S435_L0.6090.45
365_S414_I0.6090.45
287_T290_R0.6090.45
216_I269_V0.6080.45
234_A240_P0.6080.45
368_T411_S0.6070.45
372_I402_N0.6050.45
489_S498_I0.6020.45
18_V34_S0.6020.45
47_T90_L0.6000.44
117_D121_K0.6000.44
403_V481_L0.6000.44
112_R132_D0.6000.44
436_G441_L0.5990.44
460_A536_E0.5990.44
371_K463_C0.5990.44
252_D327_L0.5980.44
83_L104_K0.5970.44
140_A144_S0.5970.44
487_T501_H0.5970.44
373_D377_H0.5970.44
445_E493_G0.5960.44
44_F278_D0.5950.44
342_K346_H0.5950.44
240_P243_A0.5930.44
126_I426_L0.5930.44
51_I104_K0.5920.44
306_V374_A0.5910.43
51_I136_R0.5910.43
457_L528_V0.5910.43
16_V146_V0.5910.43
501_H508_F0.5910.43
448_I498_I0.5910.43
191_K249_D0.5900.43
348_E383_V0.5880.43
358_V374_A0.5880.43
193_G249_D0.5870.43
319_H323_K0.5870.43
179_I311_L0.5860.43
97_D104_K0.5860.43
381_H450_P0.5830.43
326_S331_V0.5830.43
77_G195_Q0.5830.43
386_L510_T0.5820.42
49_V85_N0.5820.42
534_V537_R0.5810.42
237_C490_G0.5790.42
312_E318_I0.5790.42
137_V167_L0.5780.42
378_A395_A0.5770.42
26_L174_Q0.5770.42
303_I388_L0.5750.42
406_M410_H0.5750.42
228_D231_E0.5750.42
484_D501_H0.5740.42
295_R328_E0.5740.42
406_M418_T0.5740.42
358_V531_L0.5730.42
428_E508_F0.5730.42
361_G414_I0.5710.41
323_K327_L0.5700.41
25_G171_S0.5700.41
398_E507_F0.5690.41
73_L85_N0.5690.41
136_R427_P0.5690.41
392_F498_I0.5680.41
31_T316_M0.5670.41
428_E435_L0.5670.41
436_G472_E0.5660.41
508_F529_G0.5660.41
345_D376_Q0.5660.41
207_L212_L0.5650.41
449_E489_S0.5650.41
394_L414_I0.5650.41
203_S207_L0.5650.41
126_I355_D0.5650.41
99_N102_T0.5640.41
396_V399_Y0.5640.41
202_H206_E0.5630.40
338_V351_I0.5630.40
39_L269_V0.5630.40
171_S213_Q0.5630.40
376_Q398_E0.5620.40
187_V219_G0.5610.40
314_A508_F0.5600.40
286_S290_R0.5600.40
397_V430_Y0.5590.40
446_T495_R0.5590.40
292_L361_G0.5580.40
134_K238_D0.5580.40
329_A528_V0.5580.40
140_A143_G0.5570.40
314_A394_L0.5550.40
107_Q110_I0.5550.40
49_V140_A0.5550.40
193_G311_L0.5550.40
267_Q270_M0.5540.40
324_H518_S0.5530.39
425_L430_Y0.5530.39
270_M276_V0.5520.39
403_V493_G0.5510.39
175_D397_V0.5500.39
524_S527_F0.5500.39
287_T291_D0.5500.39
535_L538_A0.5500.39
358_V386_L0.5490.39
158_I244_V0.5490.39
121_K293_V0.5490.39
410_H414_I0.5490.39
48_A95_T0.5480.39
380_E398_E0.5470.39
202_H205_K0.5470.39
510_T516_Y0.5460.39
296_E330_G0.5460.39
205_K213_Q0.5460.39
59_A149_V0.5460.39
426_L439_M0.5450.39
454_A512_F0.5450.39
195_Q221_C0.5450.39
47_T63_N0.5450.39
352_A536_E0.5440.39
139_E274_D0.5430.38
472_E495_R0.5430.38
26_L192_N0.5420.38
40_S93_D0.5420.38
251_E402_N0.5420.38
357_I377_H0.5420.38
425_L432_L0.5410.38
506_F526_P0.5410.38
25_G266_D0.5400.38
504_H527_F0.5400.38
31_T335_V0.5390.38
61_T437_G0.5390.38
112_R136_R0.5390.38
40_S519_R0.5390.38
48_A92_E0.5390.38
435_L439_M0.5380.38
392_F509_G0.5380.38
311_L386_L0.5380.38
130_T236_F0.5380.38
219_G225_L0.5370.38
450_P460_A0.5370.38
250_V255_H0.5370.38
452_T488_F0.5370.38
77_G186_L0.5360.38
340_S509_G0.5360.38
386_L509_G0.5350.38
237_C306_V0.5340.38
292_L325_A0.5340.38
63_N512_F0.5340.38
108_D135_R0.5340.38
184_V256_V0.5340.38
453_L502_D0.5330.37
446_T463_C0.5330.37
176_D240_P0.5320.37
126_I185_T0.5320.37
410_H421_P0.5320.37
144_S217_L0.5320.37
404_L502_D0.5310.37
406_M412_A0.5310.37
184_V238_D0.5310.37
168_R186_L0.5310.37
426_L517_R0.5300.37
261_E286_S0.5300.37
530_L534_V0.5300.37
62_M66_Q0.5300.37
516_Y520_P0.5290.37
112_R191_K0.5280.37
40_S316_M0.5280.37
98_H316_M0.5280.37
261_E264_G0.5270.37
368_T501_H0.5270.37
304_A378_A0.5260.37
30_I305_L0.5260.37
213_Q238_D0.5260.37
352_A383_V0.5250.37
247_N250_V0.5250.37
31_T37_R0.5250.37
36_G90_L0.5240.37
81_L122_T0.5240.37
44_F268_Y0.5230.36
444_H491_E0.5230.36
136_R171_S0.5230.36
533_A536_E0.5220.36
14_K146_V0.5210.36
233_I246_S0.5210.36
318_I327_L0.5210.36
261_E290_R0.5210.36
318_I527_F0.5210.36
16_V371_K0.5210.36
473_V477_Y0.5210.36
305_L386_L0.5190.36
95_T476_E0.5180.36
444_H495_R0.5180.36
428_E448_I0.5180.36
98_H140_A0.5170.36
294_T488_F0.5160.36
215_D271_E0.5160.36
454_A526_P0.5150.36
66_Q360_A0.5150.36
325_A509_G0.5150.36
339_D394_L0.5150.36
519_R523_A0.5140.36
100_V155_V0.5140.36
36_G394_L0.5130.35
197_T249_D0.5130.35
129_V162_P0.5120.35
478_I482_T0.5110.35
301_V324_H0.5110.35
187_V249_D0.5110.35
126_I206_E0.5100.35
85_N499_V0.5100.35
116_G157_D0.5100.35
389_C436_G0.5090.35
106_Y129_V0.5090.35
295_R523_A0.5080.35
45_D142_E0.5080.35
236_F244_V0.5070.35
74_D411_S0.5070.35
100_V105_V0.5070.35
501_H505_P0.5070.35
329_A529_G0.5060.35
131_D169_Q0.5060.35
473_V512_F0.5060.35
85_N189_Y0.5050.35
291_D407_T0.5050.35
408_G480_D0.5050.35
137_V147_C0.5040.35
142_E217_L0.5030.34
13_S337_W0.5030.34
514_P525_P0.5030.34
340_S519_R0.5030.34
19_T23_M0.5010.34
59_A192_N0.5010.34
427_P430_Y0.5010.34
378_A383_V0.5000.34
446_T491_E0.5000.34
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4zdjA 4 0.9385 100 0.416 Contact Map
3nvaA 2 0.9403 100 0.437 Contact Map
1vcoA 4 0.9349 100 0.47 Contact Map
2vo1A 4 0.4087 100 0.486 Contact Map
1s1mA 4 0.9421 100 0.526 Contact Map
2v4uA 1 0.4521 100 0.796 Contact Map
2w7tA 1 0.4503 100 0.816 Contact Map
1l9xA 1 0.425 99.9 0.902 Contact Map
3uowA 2 0.4033 99.9 0.902 Contact Map
4l8fC 3 0.4195 99.9 0.904 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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