GREMLIN Database
SYT - Threonine--tRNA ligase
UniProt: Q9HP27 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 640 (623)
Sequences: 3567 (1628)
Seq/√Len: 65.2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
498_G504_H5.9641.00
550_N595_D4.1211.00
556_R601_D3.8461.00
394_E442_E3.8281.00
124_E127_S3.4711.00
87_R124_E3.4151.00
441_R445_D3.3531.00
132_D188_S3.2651.00
394_E446_Q3.2331.00
43_D55_E3.1761.00
139_E168_P3.1301.00
77_A221_A3.1151.00
251_D344_G3.0061.00
41_K60_E2.9521.00
493_D505_Q2.9061.00
301_T305_K2.8921.00
138_V173_T2.8891.00
22_V40_G2.8421.00
293_V340_I2.8321.00
490_D505_Q2.8001.00
109_A212_E2.7291.00
37_T61_I2.6901.00
147_E150_A2.6731.00
146_R160_D2.6201.00
558_K566_V2.6121.00
525_I532_F2.5961.00
500_D504_H2.5921.00
109_A154_F2.5861.00
85_I108_I2.5171.00
254_S267_H2.4991.00
87_R131_D2.4711.00
225_E229_Q2.4441.00
80_V129_I2.4131.00
41_K68_E2.3701.00
560_E619_A2.3411.00
80_V192_I2.3211.00
42_I57_C2.3061.00
498_G502_D2.2971.00
146_R156_R2.2651.00
136_E173_T2.2561.00
422_R426_S2.2241.00
76_T135_V2.1871.00
591_L603_V2.1431.00
429_S432_I2.1401.00
544_L575_V2.1341.00
595_D599_D2.1271.00
414_D470_E2.1231.00
80_V128_I2.1111.00
224_T227_D2.1091.00
571_R581_Q2.1051.00
302_E305_K2.0981.00
423_P458_G2.0841.00
223_P227_D2.0811.00
445_D451_Y2.0701.00
627_S631_G2.0561.00
83_Q174_Q2.0501.00
539_E567_E2.0321.00
76_T186_V2.0191.00
557_V618_L2.0011.00
284_L406_E1.9841.00
284_L288_M1.9831.00
173_T178_E1.9811.00
150_A160_D1.9801.00
438_R442_E1.9621.00
558_K568_V1.9441.00
142_R164_A1.9431.00
24_D27_H1.9391.00
251_D267_H1.9331.00
543_I558_K1.9251.00
284_L287_E1.9141.00
549_D595_D1.9011.00
547_T550_N1.8901.00
398_R446_Q1.8891.00
280_Y410_T1.8551.00
86_R177_F1.8551.00
438_R441_R1.8541.00
299_F336_G1.8531.00
426_S430_D1.8511.00
620_E623_A1.8421.00
86_R152_N1.8391.00
39_A72_V1.7871.00
196_E232_L1.7781.00
269_N585_D1.7771.00
441_R453_V1.7711.00
132_D190_G1.7681.00
122_Q196_E1.7631.00
402_D447_Q1.7561.00
16_V20_A1.7411.00
60_E66_S1.7361.00
87_R176_D1.7341.00
74_R220_T1.7331.00
427_V487_N1.7250.99
564_Y629_V1.7170.99
231_Y235_R1.7120.99
187_D191_E1.7090.99
338_A508_M1.6940.99
276_E279_E1.6940.99
147_E151_D1.6790.99
555_H558_K1.6760.99
546_V575_V1.6750.99
81_L121_I1.6700.99
47_V51_E1.6690.99
154_F212_E1.6600.99
16_V28_E1.6490.99
552_G555_H1.6330.99
32_G36_D1.6100.99
280_Y406_E1.6040.99
87_R127_S1.6010.99
390_A435_Q1.6000.99
273_V521_F1.5960.99
70_L74_R1.5930.99
454_E457_D1.5780.99
556_R560_E1.5700.99
534_T625_L1.5690.99
269_N567_E1.5680.99
83_Q133_L1.5610.99
198_L235_R1.5540.99
37_T49_K1.5500.99
31_P35_R1.5500.99
401_M467_F1.5430.99
416_E476_S1.5390.99
534_T628_E1.5350.99
236_E239_K1.5210.99
531_R586_N1.5180.99
14_L28_E1.5130.99
86_R91_D1.4980.99
564_Y625_L1.4970.99
23_E27_H1.4790.98
583_H586_N1.4790.98
142_R165_G1.4750.98
245_K249_E1.4690.98
73_L223_P1.4680.98
43_D57_C1.4670.98
626_D630_D1.4560.98
444_L465_I1.4550.98
123_A126_A1.4430.98
555_H570_D1.4410.98
343_E346_W1.4390.98
208_D211_R1.4370.98
149_Y171_F1.4340.98
30_G36_D1.4300.98
297_H362_Y1.4290.98
596_D599_D1.4260.98
143_A147_E1.4230.98
561_L622_R1.4220.98
260_G263_L1.4190.98
582_A590_M1.4090.98
25_V59_I1.4080.98
202_A213_T1.4060.98
495_E503_A1.4040.98
102_E234_R1.4020.98
591_L621_F1.4010.98
134_D188_S1.3970.98
468_G476_S1.3970.98
161_A206_R1.3880.98
544_L590_M1.3860.98
397_V465_I1.3840.98
366_Q369_E1.3820.98
543_I554_A1.3800.98
583_H590_M1.3730.97
22_V47_V1.3690.97
32_G35_R1.3560.97
26_A61_I1.3560.97
138_V144_D1.3560.97
541_V625_L1.3500.97
7_T58_E1.3490.97
94_L152_N1.3480.97
553_Y593_V1.3430.97
623_A627_S1.3410.97
592_V604_S1.3400.97
278_S294_E1.3380.97
171_F178_E1.3380.97
269_N539_E1.3350.97
135_V174_Q1.3350.97
96_I158_I1.3340.97
157_E206_R1.3260.97
301_T326_E1.3250.97
346_W350_D1.3200.97
40_G61_I1.3200.97
560_E601_D1.3190.97
312_N425_K1.3180.97
542_R582_A1.3160.97
29_I33_L1.3100.97
25_V53_I1.3090.97
550_N598_E1.3070.97
148_H178_E1.3050.97
305_K311_D1.2980.96
91_D110_N1.2970.96
93_K109_A1.2930.96
46_L62_V1.2780.96
227_D230_E1.2780.96
541_V564_Y1.2730.96
266_Y521_F1.2730.96
246_L250_M1.2720.96
127_S131_D1.2670.96
69_Y223_P1.2610.96
497_T503_A1.2600.96
140_Y171_F1.2540.96
53_I57_C1.2520.96
64_D70_L1.2520.96
38_V72_V1.2510.96
542_R585_D1.2500.96
421_T453_V1.2420.95
163_A166_D1.2390.95
114_D118_L1.2380.95
17_A20_A1.2340.95
70_L73_L1.2250.95
240_E529_N1.2240.95
7_T13_T1.2210.95
41_K46_L1.2210.95
144_D147_E1.2180.95
140_Y148_H1.2170.95
141_D144_D1.2140.95
198_L220_T1.2130.95
281_V407_V1.2130.95
146_R159_L1.2120.95
21_T24_D1.2100.95
589_Y628_E1.2100.95
622_R626_D1.2080.95
391_D499_S1.2070.95
393_I484_L1.2030.94
560_E622_R1.2010.94
421_T441_R1.2000.94
272_T565_R1.2000.94
379_F516_S1.1920.94
617_D620_E1.1900.94
51_E170_S1.1880.94
346_W353_V1.1870.94
321_D324_D1.1860.94
288_M406_E1.1840.94
51_E137_R1.1820.94
624_H628_E1.1820.94
201_S213_T1.1780.94
555_H568_V1.1750.94
539_E542_R1.1720.94
26_A29_I1.1640.93
556_R559_N1.1640.93
360_K378_A1.1630.93
94_L108_I1.1620.93
272_T276_E1.1600.93
75_H98_P1.1580.93
274_L294_E1.1570.93
96_I100_T1.1570.93
354_R396_E1.1550.93
288_M403_T1.1540.93
133_L189_T1.1530.93
163_A169_V1.1500.93
281_V285_N1.1490.93
562_G626_D1.1450.93
577_K581_Q1.1440.93
256_P339_T1.1430.93
64_D73_L1.1400.93
27_H31_P1.1400.93
164_A167_G1.1390.93
338_A494_L1.1300.92
251_D254_S1.1270.92
36_D65_Q1.1250.92
40_G47_V1.1220.92
546_V576_G1.1200.92
552_G556_R1.1180.92
560_E618_L1.1180.92
75_H79_H1.1120.92
430_D434_E1.1090.92
42_I59_I1.1090.92
607_D610_E1.1080.92
605_V621_F1.1060.92
71_D99_Y1.1040.92
531_R608_R1.1010.91
135_V186_V1.1010.91
274_L278_S1.0930.91
402_D406_E1.0910.91
113_L217_V1.0910.91
344_G350_D1.0880.91
616_V624_H1.0880.91
398_R447_Q1.0880.91
310_Y328_G1.0870.91
275_R279_E1.0820.91
133_L176_D1.0790.91
60_E68_E1.0780.91
551_L570_D1.0770.90
226_S229_Q1.0750.90
7_T56_D1.0730.90
405_T409_D1.0700.90
279_E283_G1.0690.90
100_T105_Y1.0690.90
73_L77_A1.0690.90
297_H360_K1.0670.90
85_I92_A1.0660.90
432_I487_N1.0660.90
426_S434_E1.0630.90
22_V61_I1.0620.90
134_D190_G1.0620.90
254_S343_E1.0600.90
616_V621_F1.0590.90
237_E240_E1.0570.90
554_A568_V1.0560.90
137_R170_S1.0550.90
293_V337_H1.0540.90
236_E240_E1.0540.90
256_P267_H1.0500.89
64_D223_P1.0480.89
277_L514_Y1.0470.89
321_D326_E1.0450.89
76_T80_V1.0440.89
92_A108_I1.0430.89
277_L411_F1.0420.89
260_G299_F1.0390.89
23_E34_G1.0390.89
230_E233_A1.0340.89
276_E565_R1.0340.89
159_L169_V1.0330.89
611_R614_K1.0310.88
118_L219_G1.0300.88
338_A387_F1.0290.88
591_L605_V1.0250.88
543_I557_V1.0240.88
95_T152_N1.0200.88
469_F479_G1.0190.88
548_D551_L1.0190.88
285_N358_D1.0150.88
300_R325_E1.0140.88
418_A468_G1.0120.88
6_V25_V1.0120.88
131_D176_D1.0090.87
42_I53_I1.0070.87
133_L174_Q1.0050.87
10_D29_I1.0050.87
312_N427_V1.0050.87
80_V135_V1.0040.87
386_V400_L1.0040.87
88_H121_I0.9990.87
22_V59_I0.9980.87
233_A236_E0.9940.87
376_V379_F0.9930.86
442_E446_Q0.9910.86
555_H559_N0.9890.86
62_V72_V0.9880.86
226_S230_E0.9880.86
27_H34_G0.9870.86
596_D600_A0.9850.86
301_T310_Y0.9820.86
42_I47_V0.9800.86
73_L221_A0.9790.86
224_T229_Q0.9780.86
43_D58_E0.9710.85
619_A623_A0.9660.85
42_I51_E0.9660.85
531_R583_H0.9640.85
70_L223_P0.9630.85
33_L61_I0.9610.85
545_P554_A0.9590.85
389_R499_S0.9580.84
574_T577_K0.9510.84
122_Q126_A0.9510.84
273_V276_E0.9480.84
6_V59_I0.9450.84
132_D189_T0.9430.84
163_A167_G0.9430.84
271_K294_E0.9420.83
20_A24_D0.9400.83
304_W336_G0.9390.83
26_A30_G0.9360.83
417_V449_V0.9360.83
21_T52_P0.9360.83
488_M491_R0.9330.83
361_V514_Y0.9310.83
159_L163_A0.9280.83
98_P185_H0.9280.83
30_G33_L0.9270.82
93_K153_E0.9260.82
74_R221_A0.9240.82
439_Q484_L0.9230.82
108_I113_L0.9220.82
155_K179_D0.9210.82
293_V355_Y0.9200.82
62_V66_S0.9190.82
39_A62_V0.9190.82
115_A119_D0.9160.82
545_P550_N0.9130.81
143_A165_G0.9120.81
96_I206_R0.9120.81
89_H111_V0.9110.81
138_V171_F0.9100.81
79_H185_H0.9080.81
79_H98_P0.9070.81
282_R292_E0.9060.81
434_E438_R0.9060.81
188_S191_E0.9050.81
8_L30_G0.9040.81
562_G622_R0.9020.81
541_V591_L0.9010.81
595_D598_E0.9000.81
610_E613_G0.8980.80
275_R278_S0.8980.80
534_T629_V0.8960.80
601_D618_L0.8960.80
26_A34_G0.8950.80
20_A53_I0.8950.80
19_G52_P0.8930.80
96_I152_N0.8900.80
22_V25_V0.8890.80
10_D33_L0.8860.80
75_H185_H0.8850.79
133_L175_G0.8840.79
355_Y384_G0.8840.79
418_A454_E0.8830.79
8_L59_I0.8830.79
113_L119_D0.8820.79
73_L129_I0.8800.79
601_D619_A0.8780.79
181_C185_H0.8750.79
146_R150_A0.8740.79
16_V25_V0.8740.79
401_M447_Q0.8720.78
575_V578_K0.8710.78
457_D466_D0.8700.78
564_Y626_D0.8680.78
374_S522_M0.8660.78
8_L12_S0.8660.78
421_T458_G0.8660.78
548_D572_D0.8600.77
616_V620_E0.8600.77
543_I593_V0.8590.77
86_R92_A0.8580.77
233_A240_E0.8580.77
233_A237_E0.8580.77
142_R163_A0.8570.77
419_L484_L0.8570.77
53_I56_D0.8560.77
281_V358_D0.8540.77
118_L197_V0.8540.77
401_M465_I0.8540.77
263_L378_A0.8500.77
471_D475_R0.8480.76
531_R609_Q0.8470.76
553_Y557_V0.8470.76
545_P568_V0.8460.76
357_E380_T0.8440.76
543_I568_V0.8430.76
285_N356_F0.8420.76
542_R567_E0.8380.76
20_A25_V0.8360.75
602_A617_D0.8360.75
306_Q492_F0.8350.75
288_M402_D0.8340.75
209_E366_Q0.8320.75
605_V616_V0.8320.75
416_E452_D0.8320.75
285_N400_L0.8290.75
291_D355_Y0.8280.75
78_A182_K0.8270.75
106_Y155_K0.8260.75
232_L235_R0.8260.75
246_L249_E0.8250.74
266_Y518_E0.8240.74
252_L525_I0.8240.74
543_I618_L0.8190.74
382_D477_W0.8190.74
255_I264_P0.8180.74
87_R128_I0.8180.74
276_E629_V0.8180.74
142_R146_R0.8170.74
41_K62_V0.8170.74
209_E212_E0.8170.74
573_W581_Q0.8160.74
413_L486_F0.8140.73
85_I121_I0.8140.73
75_H181_C0.8130.73
73_L186_V0.8110.73
417_V467_F0.8110.73
604_S612_E0.8100.73
102_E231_Y0.8080.73
154_F211_R0.8060.73
98_P181_C0.8030.72
397_V482_V0.8020.72
157_E211_R0.8000.72
554_A593_V0.7990.72
400_L509_I0.7980.72
471_D478_D0.7980.72
26_A33_L0.7970.72
389_R392_Q0.7960.72
106_Y179_D0.7930.72
357_E361_V0.7920.71
149_Y159_L0.7920.71
395_A399_R0.7900.71
551_L555_H0.7890.71
612_E615_G0.7890.71
422_R430_D0.7870.71
382_D471_D0.7870.71
381_I512_A0.7870.71
302_E306_Q0.7860.71
584_D608_R0.7860.71
74_R223_P0.7850.71
18_S54_S0.7850.71
304_W423_P0.7820.70
22_V49_K0.7820.70
45_E51_E0.7800.70
621_F625_L0.7800.70
627_S630_D0.7800.70
553_Y598_E0.7770.70
111_V117_D0.7770.70
421_T454_E0.7750.70
77_A195_F0.7740.70
97_G183_G0.7740.70
569_E578_K0.7730.70
252_L532_F0.7710.69
198_L232_L0.7710.69
6_V57_C0.7690.69
419_L441_R0.7680.69
534_T589_Y0.7680.69
51_E54_S0.7680.69
117_D120_E0.7670.69
280_Y284_L0.7670.69
79_H97_G0.7670.69
419_L444_L0.7660.69
79_H181_C0.7650.69
8_L33_L0.7630.69
111_V120_E0.7620.68
250_M531_R0.7600.68
246_L586_N0.7580.68
250_M585_D0.7570.68
82_A177_F0.7550.68
288_M399_R0.7520.67
532_F537_A0.7500.67
110_N212_E0.7490.67
203_A213_T0.7490.67
39_A46_L0.7480.67
16_V19_G0.7480.67
437_E455_P0.7480.67
345_S503_A0.7480.67
66_S69_Y0.7450.67
339_T342_N0.7420.66
29_I32_G0.7400.66
97_G106_Y0.7400.66
234_R473_L0.7380.66
299_F328_G0.7370.66
95_T214_L0.7340.66
512_A516_S0.7330.65
157_E161_A0.7330.65
284_L410_T0.7320.65
78_A99_Y0.7300.65
407_V512_A0.7300.65
264_P378_A0.7280.65
142_R169_V0.7280.65
75_H97_G0.7280.65
342_N494_L0.7250.65
404_I413_L0.7240.65
604_S615_G0.7230.64
83_Q176_D0.7230.64
541_V566_V0.7230.64
545_P551_L0.7230.64
155_K185_H0.7220.64
434_E437_E0.7210.64
557_V561_L0.7200.64
128_I131_D0.7200.64
405_T415_Y0.7190.64
77_A80_V0.7180.64
287_E406_E0.7170.64
31_P34_G0.7170.64
98_P106_Y0.7170.64
113_L152_N0.7170.64
345_S497_T0.7170.64
16_V53_I0.7160.64
124_E131_D0.7150.64
81_L85_I0.7150.64
382_D478_D0.7150.64
291_D353_V0.7150.64
230_E234_R0.7150.64
142_R167_G0.7130.63
342_N493_D0.7130.63
589_Y621_F0.7130.63
29_I34_G0.7100.63
561_L618_L0.7090.63
70_L220_T0.7080.63
546_V550_N0.7080.63
131_D189_T0.7060.63
85_I113_L0.7060.63
545_P575_V0.7050.62
304_W458_G0.7050.62
315_D425_K0.7050.62
263_L299_F0.7050.62
38_V64_D0.7050.62
163_A168_P0.7040.62
471_D477_W0.7040.62
358_D512_A0.7020.62
274_L380_T0.7020.62
140_Y146_R0.6990.62
534_T621_F0.6970.62
65_Q227_D0.6970.62
292_E408_L0.6960.61
64_D74_R0.6950.61
420_A454_E0.6940.61
613_G616_V0.6940.61
301_T319_L0.6940.61
285_N514_Y0.6930.61
33_L63_T0.6910.61
247_G253_F0.6890.61
40_G59_I0.6880.61
567_E587_V0.6880.61
33_L37_T0.6880.61
395_A398_R0.6870.60
361_V400_L0.6870.60
148_H173_T0.6870.60
177_F180_L0.6870.60
165_G169_V0.6850.60
179_D185_H0.6850.60
310_Y408_L0.6840.60
618_L622_R0.6820.60
534_T564_Y0.6790.60
97_G179_D0.6780.59
97_G185_H0.6780.59
418_A476_S0.6760.59
126_A130_D0.6760.59
319_L328_G0.6730.59
82_A106_Y0.6730.59
95_T158_I0.6720.59
283_G563_D0.6700.59
62_V68_E0.6700.59
462_G486_F0.6670.58
8_L34_G0.6670.58
361_V380_T0.6660.58
400_L482_V0.6660.58
138_V178_E0.6640.58
564_Y622_R0.6640.58
421_T457_D0.6640.58
30_G34_G0.6640.58
268_P355_Y0.6620.58
354_R399_R0.6610.57
313_Y466_D0.6610.57
54_S57_C0.6600.57
362_Y408_L0.6590.57
36_D63_T0.6590.57
547_T595_D0.6580.57
109_A153_E0.6570.57
396_E399_R0.6560.57
561_L564_Y0.6540.57
102_E220_T0.6540.57
119_D123_A0.6540.57
436_S486_F0.6530.57
154_F213_T0.6530.57
318_F364_K0.6530.57
467_F480_P0.6520.56
6_V20_A0.6520.56
382_D523_V0.6520.56
153_E212_E0.6520.56
23_E49_K0.6480.56
487_N490_D0.6480.56
400_L404_I0.6470.56
256_P265_L0.6470.56
73_L220_T0.6460.56
31_P36_D0.6460.56
297_H378_A0.6460.56
64_D69_Y0.6460.56
96_I105_Y0.6450.56
83_Q128_I0.6450.56
453_V458_G0.6440.56
427_V491_R0.6430.55
547_T572_D0.6420.55
106_Y185_H0.6420.55
98_P155_K0.6420.55
148_H171_F0.6410.55
290_Y400_L0.6410.55
157_E205_W0.6400.55
592_V615_G0.6400.55
432_I490_D0.6400.55
46_L72_V0.6390.55
423_P479_G0.6380.55
209_E213_T0.6380.55
172_Y184_P0.6370.55
361_V374_S0.6350.55
424_E456_G0.6350.55
6_V16_V0.6350.55
422_R437_E0.6350.55
382_D475_R0.6350.55
140_Y144_D0.6340.54
75_H106_Y0.6330.54
281_V514_Y0.6320.54
284_L403_T0.6310.54
602_A615_G0.6310.54
100_T218_Y0.6300.54
20_A52_P0.6290.54
113_L215_T0.6290.54
275_R292_E0.6290.54
312_N487_N0.6280.54
100_T206_R0.6260.53
123_A226_S0.6260.53
539_E566_V0.6250.53
37_T63_T0.6250.53
8_L19_G0.6240.53
143_A146_R0.6240.53
72_V76_T0.6240.53
100_T158_I0.6240.53
521_F525_I0.6240.53
83_Q135_V0.6240.53
404_I467_F0.6230.53
229_Q233_A0.6230.53
145_A169_V0.6230.53
156_R160_D0.6230.53
19_G54_S0.6200.53
607_D628_E0.6190.53
129_I190_G0.6190.53
197_V217_V0.6180.53
89_H117_D0.6180.53
381_I516_S0.6170.52
337_H486_F0.6150.52
583_H609_Q0.6140.52
556_R598_E0.6130.52
489_P508_M0.6130.52
603_V621_F0.6120.52
328_G336_G0.6120.52
360_K380_T0.6120.52
80_V194_G0.6120.52
454_E468_G0.6110.52
48_A184_P0.6100.52
129_I195_F0.6090.51
623_A626_D0.6080.51
298_L320_L0.6060.51
272_T275_R0.6060.51
458_G479_G0.6050.51
79_H106_Y0.6050.51
329_L472_A0.6040.51
140_Y145_A0.6040.51
453_V457_D0.6020.51
197_V219_G0.6010.51
421_T444_L0.6010.51
523_V527_H0.6000.50
97_G181_C0.5980.50
431_D434_E0.5960.50
98_P183_G0.5960.50
120_E123_A0.5950.50
482_V509_I0.5950.50
522_M525_I0.5940.50
278_S337_H0.5930.50
74_R195_F0.5930.50
239_K245_K0.5930.50
101_D470_E0.5920.49
77_A192_I0.5920.49
313_Y316_D0.5920.49
160_D163_A0.5910.49
53_I59_I0.5900.49
545_P593_V0.5900.49
81_L217_V0.5880.49
22_V52_P0.5870.49
23_E50_E0.5870.49
8_L32_G0.5860.49
418_A452_D0.5860.49
234_R474_G0.5850.49
94_L149_Y0.5850.49
557_V560_E0.5850.49
275_R286_S0.5840.49
88_H124_E0.5830.48
194_G225_E0.5820.48
319_L488_M0.5820.48
79_H183_G0.5810.48
26_A40_G0.5810.48
251_D269_N0.5810.48
12_S28_E0.5810.48
137_R172_Y0.5790.48
341_F508_M0.5780.48
294_E360_K0.5770.48
496_Y504_H0.5770.48
8_L11_G0.5770.48
589_Y607_D0.5760.48
79_H155_K0.5750.47
194_G228_L0.5750.47
138_V148_H0.5740.47
143_A166_D0.5740.47
292_E480_P0.5740.47
146_R163_A0.5720.47
583_H606_R0.5710.47
353_V389_R0.5700.47
64_D186_V0.5700.47
285_N361_V0.5700.47
607_D614_K0.5690.47
541_V593_V0.5690.47
553_Y602_A0.5690.47
444_L451_Y0.5680.47
75_H155_K0.5680.47
362_Y378_A0.5680.47
109_A213_T0.5680.47
250_M532_F0.5670.47
45_E147_E0.5660.46
306_Q488_M0.5650.46
263_L297_H0.5650.46
260_G297_H0.5650.46
371_S374_S0.5650.46
155_K181_C0.5650.46
604_S613_G0.5640.46
97_G155_K0.5630.46
72_V187_D0.5630.46
25_V28_E0.5630.46
94_L177_F0.5620.46
95_T157_E0.5620.46
562_G623_A0.5610.46
92_A113_L0.5610.46
390_A504_H0.5610.46
47_V57_C0.5600.46
625_L629_V0.5600.46
328_G408_L0.5600.46
542_R593_V0.5590.46
384_G488_M0.5580.46
281_V361_V0.5570.45
478_D516_S0.5570.45
290_Y511_R0.5570.45
341_F346_W0.5560.45
571_R574_T0.5560.45
484_L509_I0.5560.45
96_I182_K0.5550.45
478_D523_V0.5550.45
305_K326_E0.5550.45
110_N113_L0.5550.45
361_V492_F0.5540.45
582_A587_V0.5540.45
14_L33_L0.5540.45
439_Q443_V0.5540.45
420_A468_G0.5530.45
77_A220_T0.5520.45
514_Y517_Y0.5520.45
170_S174_Q0.5520.45
237_E241_R0.5510.45
138_V141_D0.5510.45
275_R282_R0.5500.45
301_T328_G0.5490.44
391_D435_Q0.5480.44
285_N382_D0.5470.44
613_G624_H0.5470.44
471_D523_V0.5460.44
381_I478_D0.5460.44
115_A215_T0.5450.44
131_D175_G0.5450.44
11_G33_L0.5450.44
340_I486_F0.5440.44
250_M587_V0.5440.44
52_P55_E0.5430.44
393_I397_V0.5430.44
126_A225_E0.5430.44
310_Y314_V0.5430.44
20_A28_E0.5430.44
229_Q611_R0.5420.44
574_T580_Q0.5420.44
44_H60_E0.5420.44
12_S29_I0.5410.44
208_D212_E0.5410.44
542_R587_V0.5400.43
100_T182_K0.5390.43
274_L361_V0.5380.43
281_V356_F0.5360.43
299_F320_L0.5360.43
361_V517_Y0.5360.43
292_E358_D0.5360.43
408_L469_F0.5360.43
237_E529_N0.5360.43
285_N289_G0.5350.43
413_L428_G0.5340.43
230_E474_G0.5340.43
423_P453_V0.5330.43
407_V513_L0.5320.43
393_I439_Q0.5320.43
209_E369_E0.5320.43
411_F520_F0.5310.42
67_D452_D0.5310.42
310_Y319_L0.5310.42
475_R478_D0.5300.42
320_L328_G0.5290.42
86_R135_V0.5290.42
22_V39_A0.5290.42
185_H218_Y0.5290.42
173_T177_F0.5280.42
421_T437_E0.5280.42
123_A127_S0.5280.42
158_I161_A0.5270.42
298_L327_Y0.5270.42
608_R614_K0.5270.42
14_L25_V0.5270.42
140_Y156_R0.5270.42
45_E55_E0.5260.42
278_S517_Y0.5250.42
304_W479_G0.5240.42
320_L364_K0.5230.41
278_S358_D0.5230.41
234_R470_E0.5230.41
272_T286_S0.5230.41
286_S292_E0.5230.41
29_I61_I0.5230.41
83_Q87_R0.5220.41
282_R358_D0.5220.41
398_R402_D0.5220.41
83_Q189_T0.5210.41
28_E31_P0.5210.41
586_N609_Q0.5210.41
477_W480_P0.5200.41
106_Y181_C0.5200.41
267_H343_E0.5200.41
420_A488_M0.5180.41
469_F476_S0.5180.41
254_S265_L0.5170.41
8_L20_A0.5170.41
610_E614_K0.5170.41
404_I513_L0.5160.41
441_R455_P0.5160.41
260_G380_T0.5150.41
150_A153_E0.5140.40
274_L360_K0.5140.40
543_I603_V0.5140.40
426_S458_G0.5130.40
70_L227_D0.5120.40
12_S33_L0.5110.40
299_F469_F0.5110.40
593_V603_V0.5110.40
89_H120_E0.5110.40
389_R496_Y0.5110.40
197_V200_T0.5110.40
401_M419_L0.5100.40
471_D516_S0.5100.40
134_D189_T0.5090.40
251_D346_W0.5080.40
413_L469_F0.5070.40
141_D170_S0.5060.40
48_A51_E0.5060.40
316_D366_Q0.5060.40
304_W421_T0.5060.40
68_E71_D0.5040.39
428_G471_D0.5040.39
186_V194_G0.5040.39
285_N512_A0.5030.39
429_S487_N0.5030.39
401_M469_F0.5020.39
75_H183_G0.5010.39
261_P325_E0.5010.39
271_K360_K0.5010.39
541_V621_F0.5010.39
432_I435_Q0.5000.39
241_R529_N0.5000.39
70_L221_A0.5000.39
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1qf6A 1 0.9922 100 0.357 Contact Map
1nyrA 2 0.9906 100 0.368 Contact Map
3uh0A 2 0.6156 100 0.658 Contact Map
4hwtA 2 0.6188 100 0.66 Contact Map
1evlA 2 0.6188 100 0.661 Contact Map
3a32A 2 0.6234 100 0.671 Contact Map
3qneA 2 0.6547 100 0.721 Contact Map
2zt5A 2 0.5563 100 0.727 Contact Map
1atiA 2 0.5594 100 0.728 Contact Map
2j3lA 2 0.6281 100 0.73 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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