GREMLIN Database
Q9HNV3 - NADH dehydrogenase/oxidoreductase-like protein
UniProt: Q9HNV3 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 303 (253)
Sequences: 55605 (40292)
Seq/√Len: 2533.1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
16_G37_A3.4341.00
10_D34_D3.1481.00
65_A110_E2.7581.00
199_M216_I2.6461.00
27_E198_P2.6451.00
38_F56_G2.5621.00
95_D99_G2.5541.00
60_V63_T2.5391.00
56_G63_T2.4211.00
73_A204_L2.3381.00
61_K106_A2.3091.00
27_E31_R2.2931.00
12_L71_H2.2301.00
13_V25_C2.2061.00
14_T76_N2.1941.00
76_N118_Q2.0671.00
89_G92_R2.0181.00
10_D36_T2.0121.00
115_Y149_H2.0111.00
36_T52_T1.9361.00
143_V150_H1.9341.00
34_D52_T1.9301.00
59_T95_D1.8971.00
36_T54_I1.8971.00
119_L200_L1.8951.00
36_T71_H1.8541.00
225_A229_R1.8421.00
27_E201_A1.8371.00
155_P200_L1.8301.00
72_D114_E1.8031.00
75_V204_L1.7871.00
198_P202_D1.7801.00
105_V146_S1.7711.00
65_A107_A1.7161.00
153_V203_A1.7081.00
41_E53_R1.6981.00
66_N70_G1.6681.00
24_L75_V1.6351.00
58_V100_G1.6091.00
101_T139_A1.5911.00
11_V73_A1.5871.00
63_T66_N1.5681.00
102_E106_A1.5661.00
61_K103_N1.5661.00
26_R162_G1.5641.00
120_S124_A1.5581.00
125_D215_D1.5581.00
25_C37_A1.5531.00
170_K174_T1.5481.00
11_V33_H1.5481.00
223_T226_D1.5441.00
27_E30_D1.5121.00
74_V108_A1.5021.00
77_L119_L1.4891.00
24_L77_L1.4861.00
61_K65_A1.4811.00
9_M33_H1.4621.00
24_L197_V1.4521.00
97_H135_A1.4521.00
118_Q143_V1.4441.00
20_I158_V1.4311.00
102_E142_A1.4281.00
17_T39_A1.4231.00
226_D229_R1.4161.00
230_M234_A1.4081.00
104_V116_I1.4061.00
171_Q176_Y1.4001.00
108_A116_I1.3991.00
9_M72_D1.3931.00
91_S95_D1.3901.00
232_Y238_S1.3841.00
119_L155_P1.3761.00
230_M233_R1.3701.00
99_G102_E1.3691.00
65_A111_A1.3671.00
38_F67_A1.3641.00
64_V107_A1.3521.00
193_V197_V1.3261.00
137_G141_E1.3191.00
31_R201_A1.3131.00
256_A262_V1.3111.00
140_E154_R1.2931.00
54_I70_G1.2661.00
73_A115_Y1.2541.00
187_K221_V1.2541.00
106_A109_S1.2501.00
76_N101_T1.2481.00
94_L138_R1.2471.00
244_V250_A1.2421.00
31_R205_G1.2391.00
65_A69_D1.2121.00
154_R213_T1.2071.00
66_N69_D1.2041.00
141_E144_R1.2001.00
201_A205_G1.1991.00
132_Y136_K1.1961.00
37_A51_V1.1851.00
118_Q139_A1.1851.00
29_D51_V1.1841.00
54_I67_A1.1751.00
11_V28_L1.1721.00
27_E197_V1.1721.00
34_D50_D1.1691.00
189_Q219_P1.1571.00
10_D72_D1.1451.00
68_I107_A1.1441.00
64_V103_N1.1321.00
159_F192_W1.1311.00
68_I74_V1.1301.00
96_V100_G1.1231.00
39_A53_R1.1211.00
41_E44_D1.1121.00
75_V200_L1.1061.00
250_A253_L1.1041.00
26_R30_D1.1031.00
153_V200_L1.0971.00
19_F160_G1.0971.00
115_Y151_T1.0881.00
154_R215_D1.0871.00
16_G25_C1.0851.00
38_F64_V1.0731.00
105_V116_I1.0721.00
12_L38_F1.0671.00
69_D111_A1.0601.00
108_A113_V1.0591.00
170_K173_T1.0541.00
244_V251_V1.0531.00
155_P196_L1.0501.00
255_L259_L1.0481.00
105_V142_A1.0471.00
29_D50_D1.0381.00
99_G103_N1.0331.00
62_E65_A1.0321.00
22_T162_G1.0301.00
117_L153_V1.0291.00
62_E66_N1.0241.00
36_T70_G1.0191.00
68_I108_A1.0181.00
246_M250_A1.0141.00
254_T258_P1.0111.00
58_V78_V1.0101.00
244_V249_A1.0071.00
10_D71_H1.0021.00
214_Y258_P0.9981.00
185_A225_A0.9921.00
175_P178_T0.9901.00
68_I71_H0.9901.00
243_P250_A0.9891.00
77_L200_L0.9841.00
144_R152_I0.9821.00
118_Q152_I0.9781.00
40_R57_D0.9741.00
109_S148_L0.9691.00
27_E194_G0.9661.00
247_P250_A0.9651.00
134_R138_R0.9651.00
254_T257_D0.9641.00
258_P261_F0.9601.00
225_A243_P0.9471.00
80_L96_V0.9451.00
191_I196_L0.9441.00
120_S140_E0.9381.00
116_I143_V0.9331.00
197_V201_A0.9281.00
14_T78_V0.9271.00
61_K110_E0.9251.00
202_D206_T0.9201.00
33_H205_G0.9161.00
63_T67_A0.9121.00
106_A110_E0.9051.00
102_E138_R0.9041.00
103_N106_A0.9001.00
158_V196_L0.8991.00
192_W195_D0.8981.00
144_R213_T0.8981.00
195_D218_G0.8961.00
149_H210_W0.8951.00
169_T173_T0.8911.00
243_P249_A0.8881.00
229_R232_Y0.8881.00
11_V75_V0.8851.00
107_A111_A0.8811.00
25_C35_V0.8781.00
142_A145_S0.8711.00
114_E149_H0.8671.00
42_P55_V0.8671.00
256_A261_F0.8631.00
107_A110_E0.8561.00
168_F171_Q0.8551.00
122_L156_S0.8531.00
14_T104_V0.8521.00
23_H194_G0.8491.00
24_L119_L0.8491.00
60_V64_V0.8481.00
68_I111_A0.8461.00
38_F63_T0.8431.00
41_E55_V0.8401.00
98_L138_R0.8341.00
52_T70_G0.8311.00
248_L251_V0.8311.00
249_A252_G0.8291.00
29_D35_V0.8271.00
245_P250_A0.8241.00
243_P248_L0.8211.00
28_L201_A0.8151.00
74_V116_I0.8151.00
185_A223_T0.8151.00
247_P251_V0.8131.00
139_A143_V0.8041.00
109_S146_S0.7991.00
155_P158_V0.7941.00
19_F193_V0.7931.00
245_P249_A0.7921.00
179_G242_L0.7871.00
222_L227_V0.7831.00
9_M73_A0.7831.00
61_K107_A0.7831.00
244_V247_P0.7831.00
9_M114_E0.7791.00
59_T96_V0.7691.00
23_H27_E0.7681.00
74_V104_V0.7681.00
124_A154_R0.7651.00
94_L98_L0.7601.00
12_L56_G0.7581.00
105_V143_V0.7521.00
140_E152_I0.7471.00
232_Y239_V0.7451.00
103_N107_A0.7351.00
232_Y237_K0.7321.00
11_V204_L0.7321.00
24_L28_L0.7271.00
243_P246_M0.7231.00
198_P201_A0.7221.00
105_V109_S0.7201.00
161_D192_W0.7191.00
82_P89_G0.7191.00
255_L261_F0.7171.00
142_A146_S0.7161.00
153_V216_I0.7161.00
23_H26_R0.7101.00
102_E105_V0.7101.00
93_H135_A0.7051.00
184_G225_A0.7021.00
144_R150_H0.7001.00
106_A146_S0.7001.00
19_F162_G0.6991.00
80_L93_H0.6971.00
105_V145_S0.6961.00
97_H136_K0.6961.00
146_S150_H0.6921.00
101_T105_V0.6901.00
189_Q218_G0.6901.00
94_L99_G0.6891.00
121_A124_A0.6881.00
246_M249_A0.6851.00
123_D133_L0.6841.00
151_T203_A0.6811.00
85_K89_G0.6791.00
13_V28_L0.6771.00
36_T67_A0.6771.00
254_T261_F0.6761.00
101_T143_V0.6751.00
19_F23_H0.6741.00
248_L253_L0.6731.00
94_L135_A0.6721.00
168_F172_L0.6681.00
229_R233_R0.6681.00
201_A204_L0.6651.00
212_E254_T0.6631.00
134_R141_E0.6561.00
109_S147_D0.6551.00
73_A114_E0.6531.00
249_A253_L0.6531.00
87_S131_A0.6521.00
138_R142_A0.6511.00
108_A111_A0.6501.00
92_R95_D0.6501.00
29_D49_A0.6451.00
226_D230_M0.6441.00
131_A135_A0.6441.00
80_L92_R0.6431.00
138_R141_E0.6391.00
248_L252_G0.6361.00
33_H72_D0.6351.00
130_T133_L0.6261.00
23_H197_V0.6261.00
168_F178_T0.6251.00
177_V240_R0.6241.00
94_L134_R0.6231.00
245_P253_L0.6201.00
222_L226_D0.6171.00
245_P248_L0.6171.00
67_A70_G0.6171.00
156_S217_G0.6161.00
228_T232_Y0.6131.00
10_D33_H0.6121.00
120_S154_R0.6101.00
232_Y241_V0.6071.00
68_I113_V0.6061.00
245_P251_V0.6051.00
100_G103_N0.6041.00
141_E145_S0.6041.00
58_V64_V0.6041.00
56_G64_V0.6041.00
152_I213_T0.6021.00
9_M34_D0.6021.00
124_A140_E0.6011.00
255_L258_P0.6001.00
158_V191_I0.5991.00
80_L97_H0.5991.00
171_Q177_V0.5981.00
238_S241_V0.5971.00
76_N104_V0.5951.00
243_P251_V0.5941.00
23_H193_V0.5931.00
137_G140_E0.5931.00
232_Y235_A0.5921.00
195_D198_P0.5911.00
38_F54_I0.5911.00
209_H212_E0.5901.00
67_A71_H0.5901.00
28_L75_V0.5891.00
102_E145_S0.5881.00
68_I104_V0.5851.00
17_T41_E0.5841.00
187_K223_T0.5811.00
105_V148_L0.5771.00
86_P93_H0.5751.00
247_P253_L0.5751.00
178_T181_P0.5741.00
175_P179_G0.5731.00
116_I150_H0.5721.00
246_M251_V0.5721.00
108_A112_G0.5711.00
243_P247_P0.5701.00
175_P237_K0.5701.00
64_V68_I0.5701.00
12_L67_A0.5661.00
79_A97_H0.5661.00
176_Y179_G0.5651.00
256_A259_L0.5651.00
73_A117_L0.5651.00
101_T118_Q0.5651.00
56_G67_A0.5631.00
12_L68_I0.5611.00
257_D260_P0.5601.00
82_P92_R0.5571.00
24_L200_L0.5571.00
186_S224_L0.5551.00
134_R145_S0.5541.00
41_E45_A0.5501.00
108_A148_L0.5501.00
83_L131_A0.5471.00
159_F218_G0.5461.00
136_K139_A0.5391.00
257_D261_F0.5381.00
28_L33_H0.5381.00
244_V248_L0.5341.00
54_I63_T0.5341.00
13_V37_A0.5331.00
167_P170_K0.5321.00
153_V199_M0.5291.00
22_T26_R0.5281.00
83_L129_P0.5261.00
122_L126_P0.5241.00
92_R96_V0.5211.00
150_H211_G0.5201.00
77_L155_P0.5181.00
199_M202_D0.5181.00
39_A43_A0.5171.00
117_L203_A0.5161.00
101_T142_A0.5141.00
11_V115_Y0.5131.00
97_H132_Y0.5131.00
57_D60_V0.5111.00
189_Q221_V0.5071.00
171_Q179_G0.5061.00
125_D154_R0.5031.00
135_A139_A0.5001.00
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1sb8A 2 0.9439 100 0.31 Contact Map
2x4gA 2 0.868 100 0.313 Contact Map
3rufA 2 0.9274 100 0.314 Contact Map
3slgA 4 0.9142 100 0.315 Contact Map
2q1sA 2 0.8977 100 0.319 Contact Map
4wkgA 5 0.9571 100 0.321 Contact Map
4wokA 1 0.901 100 0.322 Contact Map
1rkxA 3 0.9109 100 0.322 Contact Map
1gy8A 2 0.9076 100 0.326 Contact Map
1i24A 4 0.9076 100 0.326 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.01 seconds.