Q9HNT7 - HALSA - GREMLIN Contacts

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Q9HNT7 - Subtilisin homolog

UniProt:	Q9HNT7	Sequences: MRQTRRTFMKTAAAAIGGLSATTQPVTAEGVRDDQFLVDTQSATSDAWREAVDVIDEAQSVGFASVSGSEQALTGYGLDFAPEFELSIDPPTITGVSPADVPDELPDGAQSASFDTTDDDIPQPHPLQWSKAEQNVAAIHDNDVTGEGTTIAIVDSGIDASHPDLTVDTSRSGNFSLDDSLGTSADSSHGTHCAGISAATGARASSGGPYAVGVAPDATLLDMKVFPFKSSASILNAAETAIRAGADAVNLSLGPSSPVSPSVSQHLSVKAYRRIGELAVDNDAVLVESAGNADTNIDDFEPQVTNTGKGSHPGWISVSGTGPRSAVPTLEAQPPDADGDGVPDFGTNSPTHTPAVYTNYGPDSVDVSAPGGNVGSSGSLWDGVFSTLSPAVDSFGFARTGPGGGSGLYAGSGMYGTLHGTSMAAPHVTGLAAVVAAQNPGATTRQIIAHIKHTAAHVRSNYQVDYFSAGDTTPDTYDNGTLEDRYASETFRGAGHIDIQRAVEKPIPFPGGLEFDGTTYYPADPDDDGVYEDVNGDGVVDMADVELLYQLALRNAVPESTTAFDVTGDGKFDMHDVQALTRQVE	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	585 (467)
Sequences:	4016 (3218)
Seq/√Len:	148.9

BACSU - SUBE SUBV SUBF WPRA SUBT APRX
HALSA - Q9HNT7 Q9HMF2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
289_S	425_A	4.979	1.00
320_G	355_A	4.709	1.00
151_I	197_S	4.579	1.00
108_G	232_A	4.333	1.00
319_S	368_S	4.320	1.00
431_L	472_T	3.899	1.00
310_G	317_S	3.704	1.00
431_L	474_P	3.673	1.00
154_V	225_V	3.461	1.00
378_G	416_G	3.452	1.00
192_H	423_M	3.125	1.00
285_V	316_I	3.113	1.00
152_A	246_A	3.080	1.00
145_T	217_D	2.987	1.00
456_A	473_T	2.949	1.00
537_D	540_V	2.868	1.00
169_T	172_S	2.806	1.00
320_G	357_Y	2.760	1.00
357_Y	372_G	2.719	1.00
194_A	222_D	2.670	1.00
355_A	372_G	2.644	1.00
289_S	424_A	2.601	1.00
55_I	59_Q	2.546	1.00
320_G	372_G	2.449	1.00
168_D	172_S	2.441	1.00
54_V	58_A	2.426	1.00
195_G	376_S	2.386	1.00
544_D	547_L	2.362	1.00
354_P	368_S	2.343	1.00
147_E	217_D	2.342	1.00
55_I	58_A	2.333	1.00
378_G	418_L	2.309	1.00
537_D	542_M	2.259	1.00
121_I	289_S	2.190	1.00
196_I	427_H	2.189	1.00
242_I	284_A	2.172	1.00
367_V	472_T	2.088	1.00
169_T	173_G	2.048	1.00
425_A	429_T	2.047	1.00
185_A	188_S	2.045	1.00
285_V	432_A	2.034	1.00
234_I	253_L	1.999	1.00
167_V	170_S	1.993	1.00
169_T	175_F	1.980	1.00
153_I	197_S	1.978	1.00
225_V	237_A	1.970	1.00
473_T	476_T	1.967	1.00
221_L	246_A	1.963	1.00
199_A	377_S	1.944	1.00
225_V	253_L	1.926	1.00
321_T	368_S	1.921	1.00
540_V	544_D	1.900	1.00
436_A	447_I	1.898	1.00
428_V	472_T	1.895	1.00
288_E	315_W	1.870	1.00
238_A	279_A	1.868	1.00
167_V	172_S	1.852	1.00
226_F	231_S	1.831	1.00
443_T	446_Q	1.823	1.00
195_G	377_S	1.823	1.00
250_N	425_A	1.822	1.00
41_Q	101_V	1.819	1.00
168_D	171_R	1.795	1.00
542_M	547_L	1.794	1.00
161_S	184_S	1.755	1.00
539_V	542_M	1.755	1.00
250_N	429_T	1.746	1.00
139_I	478_D	1.741	1.00
452_K	469_A	1.733	1.00
196_I	423_M	1.717	1.00
539_V	544_D	1.711	1.00
537_D	544_D	1.682	1.00
175_F	240_T	1.662	1.00
172_S	175_F	1.656	1.00
442_A	450_H	1.653	1.00
214_V	430_G	1.648	1.00
102_P	105_L	1.639	1.00
58_A	61_V	1.628	1.00
367_V	451_I	1.614	1.00
439_N	442_A	1.595	1.00
192_H	196_I	1.589	1.00
158_I	220_L	1.578	1.00
168_D	173_G	1.576	1.00
542_M	546_E	1.575	1.00
174_N	177_L	1.566	1.00
54_V	57_E	1.555	1.00
543_A	546_E	1.551	1.00
322_G	372_G	1.544	1.00
533_D	537_D	1.543	1.00
148_G	219_T	1.533	1.00
544_D	549_Y	1.522	1.00
93_I	105_L	1.517	1.00
438_Q	478_D	1.515	1.00
41_Q	103_D	1.507	1.00
370_P	374_V	1.502	1.00
198_A	218_A	1.499	1.00
170_S	173_G	1.497	1.00
154_V	237_A	1.474	1.00
153_I	194_A	1.465	1.00
454_T	477_Y	1.454	1.00
544_D	548_L	1.442	1.00
448_I	452_K	1.441	1.00
354_P	466_Y	1.432	1.00
167_V	171_R	1.429	1.00
59_Q	62_G	1.429	1.00
287_V	429_T	1.413	1.00
368_S	424_A	1.409	1.00
357_Y	419_H	1.394	1.00
238_A	251_L	1.394	1.00
19_L	22_T	1.394	1.00
375_G	417_T	1.391	1.00
354_P	358_T	1.390	1.00
158_I	222_D	1.385	1.00
150_T	219_T	1.380	1.00
540_V	547_L	1.376	1.00
58_A	62_G	1.375	1.00
89_D	92_T	1.374	1.00
35_Q	108_G	1.374	1.00
276_G	315_W	1.365	1.00
192_H	376_S	1.353	1.00
535_N	540_V	1.353	1.00
56_D	60_S	1.351	1.00
542_M	545_V	1.347	1.00
16_I	19_L	1.346	1.00
373_N	419_H	1.346	1.00
159_D	184_S	1.345	1.00
369_A	428_V	1.342	1.00
367_V	428_V	1.338	1.00
39_D	103_D	1.338	1.00
287_V	428_V	1.335	1.00
431_L	451_I	1.330	1.00
235_L	275_I	1.320	1.00
54_V	59_Q	1.315	1.00
543_A	547_L	1.300	1.00
55_I	60_S	1.295	1.00
59_Q	63_F	1.283	1.00
174_N	179_D	1.281	1.00
168_D	174_N	1.281	1.00
435_V	447_I	1.279	1.00
545_V	548_L	1.278	1.00
294_D	359_N	1.278	1.00
238_A	276_G	1.265	1.00
277_E	314_G	1.258	1.00
449_A	453_H	1.253	1.00
144_V	437_A	1.247	1.00
167_V	175_F	1.237	1.00
223_M	237_A	1.232	1.00
248_A	285_V	1.231	1.00
135_N	473_T	1.228	1.00
163_P	414_M	1.228	1.00
152_A	241_A	1.225	1.00
376_S	423_M	1.222	1.00
214_V	431_L	1.214	1.00
193_C	250_N	1.213	1.00
149_T	436_A	1.211	1.00
270_K	273_R	1.203	1.00
287_V	425_A	1.196	1.00
540_V	548_L	1.192	1.00
360_Y	466_Y	1.192	1.00
318_V	367_V	1.188	1.00
492_R	502_A	1.187	1.00
151_I	433_A	1.186	1.00
56_D	59_Q	1.184	1.00
316_I	428_V	1.172	1.00
496_H	499_I	1.171	1.00
58_A	63_F	1.171	1.00
523_A	527_D	1.166	1.00
165_L	194_A	1.165	1.00
165_L	377_S	1.164	1.00
542_M	549_Y	1.162	1.00
168_D	175_F	1.162	1.00
95_G	98_P	1.161	1.00
541_D	544_D	1.160	1.00
167_V	174_N	1.157	1.00
198_A	220_L	1.156	1.00
170_S	175_F	1.153	1.00
535_N	542_M	1.152	1.00
528_D	532_E	1.152	1.00
352_H	471_D	1.150	1.00
96_V	102_P	1.148	1.00
156_S	185_A	1.132	0.99
428_V	451_I	1.131	0.99
125_H	128_Q	1.130	0.99
153_I	193_C	1.127	0.99
215_A	433_A	1.126	0.99
242_I	278_L	1.123	0.99
169_T	174_N	1.116	0.99
197_S	430_G	1.114	0.99
540_V	546_E	1.106	0.99
280_V	285_V	1.104	0.99
527_D	530_V	1.102	0.99
321_T	471_D	1.099	0.99
355_A	419_H	1.098	0.99
170_S	219_T	1.092	0.99
24_Q	28_A	1.088	0.99
537_D	545_V	1.084	0.99
152_A	221_L	1.082	0.99
167_V	177_L	1.082	0.99
94_T	97_S	1.081	0.99
146_G	215_A	1.075	0.99
241_A	249_V	1.072	0.99
521_Y	527_D	1.062	0.99
435_V	477_Y	1.060	0.99
285_V	444_T	1.059	0.99
242_I	279_A	1.048	0.99
22_T	26_V	1.048	0.99
523_A	532_E	1.038	0.99
515_F	523_A	1.032	0.99
156_S	187_S	1.027	0.99
538_G	544_D	1.026	0.99
15_A	18_G	1.026	0.99
143_D	146_G	1.025	0.99
192_H	418_L	1.024	0.99
158_I	165_L	1.024	0.99
316_I	448_I	1.020	0.99
223_M	240_T	1.019	0.99
226_F	233_S	1.018	0.99
295_T	360_Y	1.016	0.99
534_V	537_D	1.015	0.99
540_V	549_Y	1.013	0.99
247_D	436_A	1.010	0.99
446_Q	483_E	1.010	0.99
538_G	542_M	1.006	0.99
169_T	176_S	1.003	0.99
149_T	433_A	1.002	0.99
537_D	547_L	1.001	0.99
273_R	312_H	1.001	0.99
234_I	251_L	1.000	0.99
240_T	244_A	0.999	0.99
223_M	244_A	0.996	0.99
60_S	64_A	0.993	0.99
108_G	111_S	0.991	0.99
542_M	548_L	0.986	0.99
171_R	174_N	0.986	0.99
527_D	532_E	0.983	0.99
151_I	218_A	0.982	0.99
167_V	173_G	0.980	0.99
186_D	228_F	0.975	0.98
171_R	175_F	0.972	0.98
182_G	185_A	0.970	0.98
537_D	548_L	0.969	0.98
124_P	127_L	0.968	0.98
214_V	427_H	0.968	0.98
240_T	243_R	0.967	0.98
312_H	315_W	0.959	0.98
418_L	423_M	0.959	0.98
224_K	227_P	0.958	0.98
520_Y	523_A	0.957	0.98
14_A	17_G	0.957	0.98
57_E	60_S	0.954	0.98
455_A	470_G	0.953	0.98
227_P	230_S	0.950	0.98
139_I	142_N	0.949	0.98
248_A	429_T	0.944	0.98
26_V	29_E	0.943	0.98
538_G	541_D	0.942	0.98
540_V	545_V	0.939	0.98
442_A	446_Q	0.939	0.98
546_E	549_Y	0.938	0.98
434_V	474_P	0.936	0.98
492_R	496_H	0.936	0.98
533_D	540_V	0.936	0.98
540_V	543_A	0.934	0.98
543_A	548_L	0.929	0.98
484_D	511_G	0.924	0.98
129_W	133_E	0.924	0.98
127_L	132_A	0.922	0.98
528_D	531_Y	0.915	0.98
238_A	249_V	0.913	0.98
160_A	184_S	0.910	0.98
64_A	68_G	0.910	0.98
538_G	549_Y	0.910	0.98
150_T	221_L	0.909	0.98
54_V	63_F	0.905	0.98
151_I	198_A	0.904	0.98
56_D	61_V	0.903	0.98
194_A	220_L	0.901	0.97
138_A	142_N	0.897	0.97
515_F	518_T	0.896	0.97
80_F	239_E	0.896	0.97
248_A	447_I	0.894	0.97
276_G	288_E	0.894	0.97
251_L	288_E	0.893	0.97
16_I	21_A	0.887	0.97
154_V	223_M	0.886	0.97
34_D	107_D	0.886	0.97
492_R	499_I	0.885	0.97
278_L	284_A	0.882	0.97
127_L	130_S	0.878	0.97
538_G	543_A	0.877	0.97
277_E	313_P	0.876	0.97
137_A	141_D	0.872	0.97
227_P	233_S	0.872	0.97
135_N	138_A	0.871	0.97
165_L	195_G	0.869	0.97
169_T	177_L	0.867	0.97
55_I	61_V	0.867	0.97
54_V	62_G	0.864	0.97
106_P	271_A	0.862	0.97
283_D	444_T	0.861	0.97
152_A	249_V	0.860	0.97
175_F	223_M	0.858	0.97
354_P	360_Y	0.857	0.97
318_V	428_V	0.856	0.97
295_T	298_D	0.855	0.97
19_L	23_T	0.853	0.96
320_G	419_H	0.849	0.96
275_I	279_A	0.849	0.96
249_V	279_A	0.849	0.96
238_A	275_I	0.847	0.96
77_G	85_E	0.844	0.96
533_D	538_G	0.844	0.96
77_G	83_E	0.844	0.96
538_G	547_L	0.843	0.96
422_S	426_P	0.841	0.96
369_A	472_T	0.840	0.96
125_H	129_W	0.839	0.96
270_K	274_R	0.838	0.96
370_P	427_H	0.838	0.96
456_A	471_D	0.835	0.96
464_V	467_F	0.834	0.96
22_T	25_P	0.832	0.96
136_V	140_H	0.832	0.96
325_S	471_D	0.830	0.96
111_S	234_I	0.828	0.96
142_N	475_D	0.824	0.96
92_T	95_G	0.823	0.96
486_Y	490_T	0.816	0.95
235_L	271_A	0.816	0.95
293_A	359_N	0.810	0.95
153_I	222_D	0.810	0.95
83_E	86_L	0.810	0.95
39_D	81_A	0.809	0.95
26_V	30_G	0.808	0.95
52_V	55_I	0.807	0.95
439_N	450_H	0.805	0.95
134_Q	214_V	0.804	0.95
126_P	214_V	0.804	0.95
167_V	176_S	0.804	0.95
435_V	474_P	0.803	0.95
62_G	65_S	0.803	0.95
475_D	479_N	0.803	0.95
432_A	447_I	0.802	0.95
77_G	84_F	0.799	0.95
188_S	418_L	0.799	0.95
122_P	125_H	0.798	0.95
233_S	236_N	0.794	0.95
122_P	128_Q	0.792	0.95
187_S	231_S	0.790	0.95
482_L	513_L	0.789	0.95
37_L	40_T	0.789	0.95
154_V	238_A	0.785	0.94
49_R	52_V	0.784	0.94
445_R	485_R	0.783	0.94
168_D	177_L	0.782	0.94
138_A	141_D	0.781	0.94
515_F	519_T	0.781	0.94
150_T	245_G	0.778	0.94
535_N	538_G	0.778	0.94
122_P	126_P	0.778	0.94
346_G	350_P	0.777	0.94
39_D	104_E	0.777	0.94
307_T	359_N	0.776	0.94
255_P	258_P	0.776	0.94
61_V	65_S	0.774	0.94
170_S	174_N	0.771	0.94
188_S	378_G	0.771	0.94
279_A	286_L	0.771	0.94
454_T	480_G	0.770	0.94
17_G	20_S	0.770	0.94
313_P	363_D	0.769	0.94
131_K	134_Q	0.769	0.94
523_A	530_V	0.768	0.94
290_A	317_S	0.768	0.94
55_I	63_F	0.768	0.94
226_F	253_L	0.767	0.94
241_A	245_G	0.766	0.94
475_D	478_D	0.766	0.94
246_A	284_A	0.765	0.94
199_A	211_A	0.765	0.94
140_H	143_D	0.764	0.94
215_A	218_A	0.763	0.94
60_S	63_F	0.763	0.94
539_V	547_L	0.763	0.94
19_L	27_T	0.762	0.94
196_I	376_S	0.758	0.93
80_F	83_E	0.758	0.93
196_I	418_L	0.756	0.93
78_L	82_P	0.755	0.93
285_V	447_I	0.755	0.93
431_L	434_V	0.753	0.93
280_V	444_T	0.753	0.93
111_S	226_F	0.753	0.93
164_D	199_A	0.749	0.93
317_S	448_I	0.749	0.93
138_A	475_D	0.748	0.93
436_A	442_A	0.747	0.93
48_W	51_A	0.744	0.93
155_D	252_S	0.742	0.93
164_D	377_S	0.742	0.93
241_A	246_A	0.742	0.93
545_V	549_Y	0.741	0.93
69_S	72_A	0.741	0.93
79_D	239_E	0.739	0.92
85_E	232_A	0.739	0.92
58_A	64_A	0.736	0.92
277_E	281_D	0.735	0.92
59_Q	66_V	0.734	0.92
225_V	251_L	0.731	0.92
123_Q	126_P	0.729	0.92
224_K	228_F	0.728	0.92
39_D	106_P	0.728	0.92
533_D	542_M	0.726	0.92
35_Q	87_S	0.726	0.92
150_T	246_A	0.724	0.92
93_I	97_S	0.723	0.92
137_A	140_H	0.721	0.92
23_T	27_T	0.721	0.92
54_V	61_V	0.721	0.92
155_D	189_H	0.719	0.91
17_G	23_T	0.719	0.91
435_V	442_A	0.717	0.91
436_A	440_P	0.717	0.91
492_R	497_I	0.715	0.91
423_M	426_P	0.714	0.91
253_L	288_E	0.713	0.91
66_V	70_E	0.712	0.91
193_C	425_A	0.712	0.91
317_S	366_D	0.711	0.91
498_D	501_R	0.710	0.91
148_G	215_A	0.707	0.91
366_D	452_K	0.706	0.91
223_M	241_A	0.705	0.91
423_M	427_H	0.705	0.91
486_Y	491_F	0.704	0.91
140_H	145_T	0.703	0.90
245_G	284_A	0.701	0.90
25_P	28_A	0.700	0.90
79_D	83_E	0.700	0.90
171_R	176_S	0.699	0.90
73_L	76_Y	0.697	0.90
144_V	438_Q	0.694	0.90
24_Q	27_T	0.694	0.90
373_N	417_T	0.693	0.90
288_E	310_G	0.693	0.90
163_P	166_T	0.692	0.90
51_A	55_I	0.690	0.90
21_A	25_P	0.690	0.90
171_R	177_L	0.689	0.90
537_D	546_E	0.685	0.89
171_R	221_L	0.683	0.89
39_D	42_S	0.682	0.89
432_A	435_V	0.681	0.89
64_A	69_S	0.679	0.89
292_N	422_S	0.679	0.89
53_D	58_A	0.678	0.89
321_T	354_P	0.677	0.89
234_I	237_A	0.677	0.89
55_I	62_G	0.677	0.89
80_F	242_I	0.676	0.89
346_G	349_S	0.676	0.89
521_Y	531_Y	0.676	0.89
316_I	432_A	0.675	0.89
409_Y	412_S	0.674	0.89
525_P	528_D	0.668	0.88
75_G	85_E	0.668	0.88
46_D	52_V	0.667	0.88
47_A	51_A	0.666	0.88
535_N	549_Y	0.665	0.88
158_I	194_A	0.664	0.88
252_S	426_P	0.664	0.88
51_A	54_V	0.662	0.88
529_G	532_E	0.662	0.88
193_C	196_I	0.661	0.88
27_T	31_V	0.660	0.87
123_Q	128_Q	0.658	0.87
527_D	531_Y	0.658	0.87
54_V	60_S	0.658	0.87
323_P	374_V	0.658	0.87
538_G	545_V	0.657	0.87
14_A	19_L	0.657	0.87
149_T	437_A	0.657	0.87
457_H	464_V	0.654	0.87
62_G	66_V	0.654	0.87
173_G	177_L	0.652	0.87
255_P	259_V	0.652	0.87
374_V	427_H	0.650	0.87
464_V	469_A	0.649	0.87
251_L	276_G	0.649	0.87
182_G	224_K	0.648	0.87
135_N	475_D	0.647	0.86
280_V	448_I	0.646	0.86
516_D	523_A	0.644	0.86
359_N	365_V	0.642	0.86
170_S	176_S	0.641	0.86
165_L	169_T	0.641	0.86
537_D	543_A	0.641	0.86
362_P	365_V	0.640	0.86
96_V	99_A	0.640	0.86
483_E	514_E	0.639	0.86
163_P	413_G	0.639	0.86
18_G	26_V	0.638	0.86
482_L	523_A	0.638	0.86
39_D	278_L	0.637	0.86
146_G	434_V	0.635	0.85
237_A	241_A	0.633	0.85
308_G	311_S	0.630	0.85
59_Q	64_A	0.629	0.85
62_G	70_E	0.629	0.85
172_S	222_D	0.627	0.85
142_N	479_N	0.627	0.85
242_I	282_N	0.627	0.85
125_H	130_S	0.626	0.85
287_V	316_I	0.625	0.85
536_G	542_M	0.625	0.85
130_S	427_H	0.624	0.84
18_G	24_Q	0.624	0.84
49_R	53_D	0.623	0.84
174_N	224_K	0.622	0.84
45_S	48_W	0.622	0.84
168_D	200_T	0.621	0.84
536_G	543_A	0.619	0.84
533_D	539_V	0.619	0.84
287_V	432_A	0.619	0.84
130_S	134_Q	0.619	0.84
511_G	515_F	0.616	0.84
168_D	176_S	0.615	0.84
189_H	422_S	0.615	0.84
192_H	374_V	0.614	0.83
372_G	419_H	0.614	0.83
21_A	26_V	0.613	0.83
120_D	156_S	0.612	0.83
239_E	278_L	0.612	0.83
509_F	515_F	0.606	0.83
61_V	64_A	0.606	0.83
57_E	61_V	0.605	0.83
197_S	218_A	0.605	0.83
66_V	71_Q	0.605	0.83
533_D	544_D	0.604	0.82
139_I	475_D	0.602	0.82
123_Q	130_S	0.602	0.82
280_V	286_L	0.600	0.82
347_T	350_P	0.600	0.82
536_G	539_V	0.598	0.82
136_V	139_I	0.598	0.82
14_A	18_G	0.597	0.82
253_L	272_Y	0.597	0.82
539_V	543_A	0.596	0.82
254_G	289_S	0.595	0.82
123_Q	127_L	0.595	0.82
543_A	549_Y	0.594	0.81
241_A	279_A	0.594	0.81
204_A	208_G	0.594	0.81
192_H	427_H	0.592	0.81
513_L	516_D	0.591	0.81
53_D	57_E	0.591	0.81
154_V	251_L	0.591	0.81
128_Q	131_K	0.590	0.81
156_S	254_G	0.588	0.81
256_S	293_A	0.588	0.81
450_H	480_G	0.587	0.81
67_S	70_E	0.587	0.81
61_V	68_G	0.587	0.81
221_L	244_A	0.586	0.81
273_R	276_G	0.586	0.81
140_H	434_V	0.586	0.81
88_I	92_T	0.585	0.80
109_A	269_V	0.585	0.80
111_S	255_P	0.584	0.80
23_T	26_V	0.583	0.80
255_P	309_K	0.582	0.80
58_A	67_S	0.581	0.80
20_S	23_T	0.579	0.80
164_D	211_A	0.579	0.80
350_P	353_T	0.579	0.80
536_G	540_V	0.577	0.80
191_T	377_S	0.577	0.80
149_T	152_A	0.577	0.80
62_G	67_S	0.575	0.79
296_N	307_T	0.575	0.79
149_T	248_A	0.575	0.79
533_D	547_L	0.574	0.79
350_P	460_S	0.573	0.79
280_V	445_R	0.572	0.79
52_V	58_A	0.570	0.79
17_G	26_V	0.569	0.79
15_A	20_S	0.569	0.79
482_L	485_R	0.568	0.78
535_N	546_E	0.567	0.78
56_D	63_F	0.566	0.78
241_A	286_L	0.565	0.78
145_T	437_A	0.565	0.78
327_V	344_D	0.564	0.78
65_S	69_S	0.563	0.78
46_D	53_D	0.563	0.78
20_S	25_P	0.563	0.78
146_G	218_A	0.562	0.78
518_T	521_Y	0.561	0.78
503_V	523_A	0.561	0.78
35_Q	38_V	0.561	0.78
131_K	136_V	0.560	0.78
189_H	292_N	0.560	0.78
40_T	84_F	0.559	0.77
446_Q	514_E	0.559	0.77
140_H	144_V	0.557	0.77
290_A	424_A	0.556	0.77
535_N	547_L	0.556	0.77
369_A	424_A	0.556	0.77
497_I	500_Q	0.554	0.77
201_G	212_V	0.554	0.77
20_S	26_V	0.554	0.77
128_Q	133_E	0.553	0.77
367_V	431_L	0.553	0.77
43_A	46_D	0.551	0.76
250_N	287_V	0.551	0.76
173_G	176_S	0.549	0.76
248_A	518_T	0.547	0.76
18_G	25_P	0.547	0.76
534_V	539_V	0.546	0.76
534_V	538_G	0.545	0.76
51_A	58_A	0.545	0.76
435_V	478_D	0.544	0.75
314_G	445_R	0.544	0.75
409_Y	413_G	0.543	0.75
421_T	426_P	0.543	0.75
193_C	424_A	0.543	0.75
170_S	221_L	0.542	0.75
27_T	30_G	0.540	0.75
449_A	485_R	0.540	0.75
160_A	172_S	0.538	0.75
451_I	477_Y	0.538	0.75
254_G	258_P	0.537	0.75
294_D	354_P	0.537	0.75
159_D	162_H	0.536	0.74
254_G	309_K	0.536	0.74
175_F	237_A	0.535	0.74
445_R	449_A	0.535	0.74
146_G	216_P	0.535	0.74
152_A	223_M	0.535	0.74
319_S	365_V	0.535	0.74
156_S	191_T	0.535	0.74
18_G	23_T	0.534	0.74
154_V	253_L	0.533	0.74
170_S	177_L	0.533	0.74
164_D	415_Y	0.531	0.74
515_F	521_Y	0.530	0.74
79_D	82_P	0.530	0.74
483_E	516_D	0.529	0.73
201_G	204_A	0.529	0.73
538_G	548_L	0.528	0.73
534_V	546_E	0.528	0.73
174_N	178_D	0.527	0.73
16_I	20_S	0.526	0.73
160_A	183_T	0.525	0.73
25_P	38_V	0.525	0.73
481_T	484_D	0.524	0.73
193_C	423_M	0.524	0.73
70_E	76_Y	0.524	0.73
295_T	307_T	0.524	0.73
234_I	272_Y	0.523	0.73
481_T	517_G	0.523	0.73
160_A	165_L	0.523	0.73
156_S	188_S	0.522	0.72
122_P	127_L	0.522	0.72
379_S	413_G	0.520	0.72
106_P	238_A	0.520	0.72
539_V	549_Y	0.519	0.72
503_V	507_I	0.519	0.72
124_P	128_Q	0.517	0.72
307_T	310_G	0.517	0.72
199_A	202_A	0.516	0.72
121_I	125_H	0.515	0.71
379_S	411_G	0.515	0.71
349_S	353_T	0.515	0.71
536_G	545_V	0.515	0.71
522_P	543_A	0.515	0.71
182_G	186_D	0.514	0.71
463_Q	466_Y	0.513	0.71
367_V	455_A	0.513	0.71
199_A	210_Y	0.513	0.71
539_V	548_L	0.512	0.71
235_L	272_Y	0.511	0.71
317_S	364_S	0.510	0.71
57_E	63_F	0.510	0.71
155_D	190_G	0.510	0.71
140_H	212_V	0.509	0.71
23_T	28_A	0.509	0.71
521_Y	525_P	0.509	0.71
533_D	536_G	0.509	0.71
277_E	312_H	0.508	0.70
55_I	64_A	0.507	0.70
523_A	529_G	0.507	0.70
242_I	245_G	0.507	0.70
50_E	53_D	0.505	0.70
251_L	309_K	0.504	0.70
46_D	49_R	0.503	0.70
415_Y	423_M	0.502	0.70
15_A	21_A	0.502	0.70
15_A	19_L	0.500	0.69
32_R	38_V	0.500	0.69

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3whiA	2	0.6034	100	0.407	Contact Map
3afgA	1	0.8085	100	0.411	Contact Map
3wiuA	2	0.5983	100	0.423	Contact Map
1xf1A	2	0.6974	100	0.423	Contact Map
1r6vA	1	0.8462	100	0.425	Contact Map
3t41A	1	0.6615	100	0.428	Contact Map
4tr2A	2	0.6325	100	0.432	Contact Map
3vtaA	1	0.694	100	0.448	Contact Map
2p4eP	2	0.7385	100	0.452	Contact Map
3i6sA	2	0.6991	100	0.454	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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