GLPK - HALSA - GREMLIN Contacts

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GLPK - Glycerol kinase

UniProt:	Q9HNS5	Sequences: MTDAYVGAIDQGTTGTRFIVFDQHGDVVANTYEKHEQHYPEPGWVEHDPLEIWENTKSVVTAGLSAAGLDADDLAAIGITNQRETTVVWDAASGRPIHNALVWQDRRTTSRVESLEENGKIERIREKTGLEADAYFSATKTEWLLDEAEPLKLSSARASSLRDRARDGELLMGTIDSWLIYNLTGEHITDVSNASRTMLYNITDLEWDDWLLEEFDIPREMLPEVRPSSDEAVYGHTDPDGFLGAAVPVTAALGDQQAALFGQTCFDAGDAKNTYGTGSFYLMNTGEDAVSSEHGLLTTIGFQLSGEPVQYALEGSIFVTGAAIEWLEDVDLINNAAQTAELASSVDTTDGVYMVPAFTGLGAPHWDGRARGTLVGMTRGTRKAHIVRATLESIAYQTRDIAAAMEADSGVSTTTLRVDGGAVKNNFLCQLQSDIIQTDLARPEVDETTALGAAYAAGLAVGYWDSLDDLRENWRVDRSFEPEMDPSEADSKYGRWEDAVDRSLAWATED	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	510 (473)
Sequences:	12481 (8592)
Seq/√Len:	395.0

ECOLI - GLPK LYXK ARAB LSRK XYLB RHAB FUCK YGCE
BACSU - GNTK GLPK XYLB ARAB YOAC RHAB
HALSA - GLPK
SULSO - GLPK1 GLPK2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
209_D	219_R	4.084	1.00
111_R	146_D	3.816	1.00
22_D	26_D	3.484	1.00
18_F	59_V	3.306	1.00
114_S	146_D	3.262	1.00
235_G	238_D	2.957	1.00
399_R	493_Y	2.886	1.00
201_N	204_D	2.852	1.00
439_D	481_E	2.809	1.00
399_R	403_A	2.799	1.00
127_K	208_D	2.796	1.00
406_E	438_T	2.753	1.00
33_E	58_S	2.721	1.00
430_Q	434_D	2.663	1.00
426_N	478_R	2.627	1.00
38_H	99_N	2.614	1.00
374_L	386_I	2.613	1.00
466_S	469_D	2.582	1.00
200_Y	225_V	2.574	1.00
415_T	441_A	2.573	1.00
31_T	62_A	2.568	1.00
33_E	62_A	2.563	1.00
227_P	230_D	2.523	1.00
465_D	469_D	2.519	1.00
98_H	148_A	2.467	1.00
20_V	63_G	2.419	1.00
53_W	182_N	2.415	1.00
97_I	151_L	2.412	1.00
346_V	385_H	2.392	1.00
50_L	182_N	2.391	1.00
206_E	219_R	2.371	1.00
399_R	490_D	2.271	1.00
90_D	93_S	2.270	1.00
212_L	219_R	2.265	1.00
201_N	208_D	2.252	1.00
91_A	168_G	2.228	1.00
335_N	338_Q	2.224	1.00
334_N	338_Q	2.192	1.00
186_E	224_E	2.156	1.00
57_K	240_D	2.153	1.00
253_L	258_A	2.094	1.00
209_D	213_E	2.086	1.00
9_I	56_T	2.080	1.00
19_I	450_A	2.079	1.00
180_I	252_A	2.073	1.00
350_D	385_H	2.019	1.00
483_E	486_P	1.980	1.00
323_A	390_T	1.958	1.00
15_G	32_Y	1.951	1.00
114_S	118_N	1.947	1.00
234_Y	237_T	1.921	1.00
50_L	95_R	1.911	1.00
184_T	249_V	1.910	1.00
123_R	126_E	1.901	1.00
382_R	385_H	1.889	1.00
169_E	187_H	1.889	1.00
406_E	412_S	1.875	1.00
6_V	458_G	1.872	1.00
444_E	475_R	1.865	1.00
338_Q	341_E	1.855	1.00
41_E	44_W	1.853	1.00
36_E	51_E	1.852	1.00
5_Y	28_V	1.844	1.00
353_Y	495_R	1.844	1.00
354_M	374_L	1.834	1.00
279_S	320_T	1.831	1.00
7_G	60_V	1.819	1.00
418_V	429_C	1.813	1.00
437_Q	487_S	1.806	1.00
345_S	384_A	1.801	1.00
493_Y	497_E	1.788	1.00
250_T	460_A	1.777	1.00
62_A	66_A	1.775	1.00
11_Q	16_T	1.765	1.00
7_G	18_F	1.761	1.00
142_E	146_D	1.753	1.00
188_I	226_R	1.721	1.00
327_L	390_T	1.717	1.00
441_A	479_S	1.708	1.00
123_R	210_W	1.691	1.00
127_K	210_W	1.686	1.00
123_R	127_K	1.684	1.00
234_Y	238_D	1.665	1.00
233_V	238_D	1.657	1.00
113_E	117_E	1.655	1.00
94_G	181_Y	1.650	1.00
233_V	236_H	1.642	1.00
325_E	329_D	1.638	1.00
434_D	483_E	1.633	1.00
336_A	339_T	1.620	1.00
226_R	230_D	1.616	1.00
434_D	486_P	1.614	1.00
5_Y	20_V	1.606	1.00
439_D	479_S	1.600	1.00
88_V	144_L	1.587	1.00
110_S	114_S	1.587	1.00
268_A	286_G	1.583	1.00
90_D	95_R	1.564	1.00
396_Y	492_K	1.562	1.00
371_R	378_T	1.555	1.00
270_D	415_T	1.540	1.00
87_V	175_I	1.540	1.00
88_V	221_M	1.527	1.00
116_E	121_I	1.524	1.00
403_A	497_E	1.498	1.00
6_V	463_Y	1.483	1.00
38_H	51_E	1.464	1.00
403_A	406_E	1.459	1.00
485_D	488_E	1.457	1.00
48_D	51_E	1.454	1.00
487_S	490_D	1.442	1.00
63_G	67_A	1.433	1.00
341_E	345_S	1.425	1.00
31_T	59_V	1.421	1.00
53_W	57_K	1.413	1.00
29_A	63_G	1.394	1.00
340_A	344_S	1.389	1.00
122_E	126_E	1.384	1.00
388_R	392_E	1.382	1.00
354_M	358_F	1.382	1.00
50_L	54_E	1.380	1.00
427_F	431_L	1.376	1.00
426_N	442_R	1.372	1.00
31_T	63_G	1.366	1.00
244_G	247_V	1.366	1.00
444_E	477_D	1.363	1.00
458_G	464_W	1.361	1.00
29_A	66_A	1.361	1.00
143_W	147_E	1.353	1.00
426_N	480_F	1.338	1.00
64_L	71_A	1.322	1.00
178_W	182_N	1.313	1.00
337_A	340_A	1.313	1.00
239_P	245_A	1.312	1.00
317_I	397_Q	1.307	1.00
76_A	457_A	1.307	1.00
9_I	60_V	1.302	1.00
486_P	489_A	1.299	1.00
342_L	384_A	1.295	1.00
275_Y	432_Q	1.291	1.00
70_D	73_D	1.281	1.00
395_A	431_L	1.278	1.00
83_R	254_G	1.273	1.00
148_A	151_L	1.270	1.00
180_I	188_I	1.268	1.00
415_T	439_D	1.266	1.00
191_V	205_L	1.264	1.00
342_L	345_S	1.263	1.00
339_T	387_V	1.263	1.00
442_R	480_F	1.256	1.00
395_A	435_I	1.256	1.00
109_T	113_E	1.253	1.00
271_A	413_T	1.250	1.00
218_P	221_M	1.249	1.00
111_R	142_E	1.242	1.00
23_Q	463_Y	1.239	1.00
361_L	364_P	1.235	1.00
273_N	432_Q	1.231	1.00
395_A	432_Q	1.226	1.00
437_Q	489_A	1.223	1.00
91_A	171_L	1.221	1.00
424_K	446_D	1.213	1.00
54_E	58_S	1.211	1.00
29_A	67_A	1.211	1.00
16_T	56_T	1.211	1.00
123_R	214_E	1.210	1.00
343_A	427_F	1.195	1.00
226_R	234_Y	1.193	1.00
235_G	239_P	1.188	1.00
354_M	390_T	1.185	1.00
341_E	344_S	1.185	1.00
20_V	67_A	1.184	1.00
138_A	215_F	1.183	1.00
85_T	100_A	1.177	1.00
429_C	480_F	1.174	1.00
124_I	132_A	1.166	1.00
16_T	55_N	1.161	1.00
233_V	250_T	1.161	1.00
48_D	99_N	1.160	1.00
253_L	456_A	1.157	1.00
437_Q	490_D	1.156	1.00
210_W	213_E	1.154	1.00
9_I	18_F	1.151	1.00
403_A	493_Y	1.151	1.00
488_E	491_S	1.149	1.00
431_L	435_I	1.145	1.00
212_L	222_L	1.143	1.00
352_V	381_T	1.142	1.00
319_V	323_A	1.138	1.00
267_D	270_D	1.136	1.00
118_N	214_E	1.136	1.00
342_L	383_K	1.136	1.00
191_V	225_V	1.135	1.00
94_G	187_H	1.133	1.00
21_F	27_V	1.131	1.00
236_H	246_A	1.129	1.00
267_D	471_R	1.128	1.00
319_V	322_A	1.124	1.00
372_G	377_M	1.120	1.00
61_T	240_D	1.119	1.00
58_S	62_A	1.119	1.00
56_T	179_L	1.118	1.00
399_R	436_I	1.117	1.00
377_M	381_T	1.116	1.00
330_V	386_I	1.116	1.00
400_D	497_E	1.113	1.00
230_D	234_Y	1.110	1.00
233_V	237_T	1.098	1.00
287_E	308_P	1.094	1.00
483_E	487_S	1.088	1.00
180_I	234_Y	1.083	1.00
203_T	289_A	1.082	1.00
490_D	494_G	1.081	1.00
336_A	340_A	1.081	1.00
46_E	99_N	1.081	1.00
5_Y	73_D	1.080	1.00
120_K	123_R	1.078	1.00
375_V	499_A	1.078	1.00
120_K	214_E	1.075	1.00
110_S	113_E	1.072	1.00
88_V	141_T	1.068	1.00
62_A	65_S	1.064	1.00
21_F	454_A	1.060	1.00
495_R	498_D	1.059	1.00
20_V	69_L	1.058	1.00
49_P	87_V	1.058	1.00
64_L	67_A	1.051	1.00
6_V	461_V	1.045	1.00
88_V	167_D	1.043	1.00
191_V	200_Y	1.041	1.00
144_L	151_L	1.040	1.00
267_D	468_D	1.033	1.00
112_V	132_A	1.032	1.00
52_I	175_I	1.031	1.00
76_A	461_V	1.030	1.00
56_T	60_V	1.022	1.00
402_A	436_I	1.020	1.00
270_D	417_R	1.020	1.00
381_T	385_H	1.019	1.00
459_L	470_L	1.018	1.00
79_I	180_I	1.017	1.00
111_R	147_E	1.013	1.00
113_E	116_E	1.010	1.00
455_Y	470_L	1.003	1.00
98_H	151_L	1.003	1.00
340_A	426_N	1.002	1.00
396_Y	435_I	1.002	1.00
269_G	414_T	1.001	1.00
37_Q	47_H	0.999	1.00
417_R	441_A	0.999	1.00
77_I	247_V	0.997	1.00
184_T	235_G	0.997	1.00
271_A	283_M	0.992	1.00
212_L	217_I	0.991	1.00
111_R	114_S	0.990	1.00
455_Y	473_N	0.987	1.00
394_I	422_A	0.982	1.00
114_S	117_E	0.978	1.00
35_H	55_N	0.977	1.00
51_E	54_E	0.974	1.00
107_R	143_W	0.968	1.00
22_D	28_V	0.968	1.00
205_L	227_P	0.966	1.00
399_R	435_I	0.964	1.00
181_Y	187_H	0.959	1.00
6_V	76_A	0.958	1.00
57_K	61_T	0.956	1.00
323_A	354_M	0.956	1.00
31_T	66_A	0.955	1.00
69_L	73_D	0.954	1.00
250_T	461_V	0.953	1.00
45_V	104_Q	0.952	1.00
458_G	463_Y	0.951	1.00
267_D	414_T	0.949	1.00
64_L	74_L	0.947	1.00
303_Q	309_V	0.946	1.00
5_Y	69_L	0.944	1.00
388_R	427_F	0.939	1.00
76_A	250_T	0.937	1.00
354_M	389_A	0.932	1.00
267_D	472_E	0.928	1.00
476_V	479_S	0.928	1.00
95_R	182_N	0.927	1.00
340_A	343_A	0.925	1.00
138_A	198_M	0.922	1.00
469_D	472_E	0.921	1.00
124_I	198_M	0.920	1.00
200_Y	204_D	0.920	1.00
422_A	428_L	0.912	1.00
272_K	419_D	0.910	1.00
436_I	439_D	0.910	1.00
281_Y	402_A	0.908	1.00
18_F	63_G	0.906	1.00
79_I	179_L	0.905	1.00
415_T	479_S	0.905	1.00
7_G	20_V	0.902	1.00
72_D	244_G	0.900	1.00
364_P	367_D	0.899	1.00
233_V	460_A	0.898	1.00
286_G	310_Q	0.898	1.00
75_A	461_V	0.892	1.00
171_L	187_H	0.892	1.00
484_M	487_S	0.890	1.00
377_M	386_I	0.888	1.00
396_Y	493_Y	0.883	1.00
167_D	170_L	0.883	1.00
279_S	398_T	0.882	1.00
333_I	339_T	0.880	1.00
207_W	222_L	0.880	1.00
21_F	451_L	0.879	1.00
484_M	488_E	0.879	1.00
177_S	189_T	0.874	1.00
114_S	142_E	0.873	1.00
7_G	74_L	0.872	1.00
20_V	74_L	0.872	1.00
484_M	489_A	0.869	1.00
78_G	250_T	0.867	1.00
80_T	449_T	0.867	1.00
189_T	194_A	0.866	1.00
142_E	145_L	0.864	1.00
464_W	470_L	0.863	1.00
416_L	436_I	0.862	1.00
403_A	407_A	0.860	1.00
126_E	203_T	0.859	1.00
340_A	425_N	0.859	1.00
348_T	351_G	0.852	1.00
284_N	310_Q	0.849	1.00
191_V	227_P	0.845	1.00
205_L	309_V	0.844	1.00
98_H	144_L	0.841	1.00
89_W	94_G	0.838	1.00
326_W	329_D	0.834	1.00
11_Q	179_L	0.828	1.00
33_E	59_V	0.828	1.00
371_R	375_V	0.825	1.00
61_T	65_S	0.825	1.00
110_S	147_E	0.822	1.00
342_L	387_V	0.821	1.00
259_A	419_D	0.818	1.00
374_L	390_T	0.817	1.00
191_V	303_Q	0.815	1.00
349_T	353_Y	0.812	1.00
188_I	224_E	0.812	1.00
459_L	466_S	0.810	1.00
391_L	431_L	0.807	1.00
459_L	467_L	0.804	1.00
79_I	183_L	0.803	1.00
112_V	139_T	0.802	1.00
283_M	405_M	0.800	1.00
346_V	349_T	0.800	1.00
206_E	224_E	0.799	1.00
213_E	219_R	0.797	1.00
116_E	132_A	0.796	1.00
51_E	55_N	0.795	1.00
90_D	169_E	0.795	1.00
138_A	199_L	0.794	1.00
360_G	364_P	0.794	1.00
338_Q	342_L	0.792	1.00
280_F	316_S	0.792	1.00
194_A	207_W	0.790	1.00
206_E	209_D	0.785	1.00
84_E	196_R	0.785	1.00
74_L	247_V	0.784	1.00
34_K	325_E	0.784	1.00
491_S	495_R	0.784	1.00
110_S	146_D	0.783	1.00
21_F	445_V	0.783	1.00
370_A	373_T	0.782	1.00
237_T	241_G	0.781	1.00
75_A	463_Y	0.779	1.00
91_A	166_R	0.778	1.00
83_R	193_N	0.777	1.00
106_R	133_D	0.777	1.00
86_T	172_M	0.776	1.00
343_A	346_V	0.775	1.00
233_V	248_P	0.775	1.00
11_Q	56_T	0.775	1.00
441_A	476_V	0.770	1.00
189_T	223_P	0.770	1.00
141_T	199_L	0.769	1.00
27_V	30_N	0.768	1.00
112_V	134_A	0.768	1.00
402_A	406_E	0.768	1.00
430_Q	483_E	0.765	1.00
185_G	238_D	0.760	1.00
40_P	44_W	0.758	1.00
361_L	367_D	0.756	1.00
189_T	225_V	0.756	1.00
188_I	234_Y	0.756	1.00
353_Y	375_V	0.754	1.00
418_V	442_R	0.754	1.00
351_G	492_K	0.753	1.00
126_E	291_S	0.752	1.00
273_N	279_S	0.752	1.00
89_W	171_L	0.752	1.00
488_E	492_K	0.751	1.00
239_P	246_A	0.750	1.00
200_Y	205_L	0.750	1.00
89_W	187_H	0.748	1.00
256_Q	280_F	0.748	1.00
127_K	201_N	0.748	1.00
418_V	432_Q	0.745	1.00
263_Q	272_K	0.745	1.00
344_S	427_F	0.744	1.00
271_A	416_L	0.743	1.00
404_A	407_A	0.740	1.00
46_E	107_R	0.740	1.00
60_V	64_L	0.740	1.00
332_L	338_Q	0.739	1.00
399_R	497_E	0.738	1.00
33_E	55_N	0.737	1.00
391_L	425_N	0.736	1.00
210_W	214_E	0.736	1.00
491_S	494_G	0.736	1.00
30_N	447_E	0.733	1.00
226_R	251_A	0.732	1.00
327_L	386_I	0.732	1.00
8_A	78_G	0.731	1.00
167_D	221_M	0.731	1.00
423_V	446_D	0.731	1.00
205_L	303_Q	0.730	1.00
49_P	99_N	0.730	1.00
90_D	168_G	0.728	1.00
83_R	314_E	0.728	1.00
435_I	489_A	0.728	1.00
273_N	398_T	0.728	1.00
192_S	302_F	0.726	1.00
358_F	361_L	0.723	1.00
103_W	278_G	0.723	1.00
90_D	166_R	0.723	1.00
400_D	493_Y	0.721	1.00
71_A	74_L	0.719	1.00
395_A	428_L	0.718	1.00
50_L	178_W	0.716	1.00
346_V	350_D	0.715	1.00
34_K	328_E	0.715	1.00
285_T	313_L	0.715	1.00
474_W	477_D	0.714	1.00
54_E	57_K	0.713	1.00
492_K	495_R	0.712	1.00
13_T	102_V	0.710	1.00
396_Y	489_A	0.709	1.00
208_D	211_L	0.707	1.00
263_Q	419_D	0.706	1.00
35_H	47_H	0.705	1.00
176_D	252_A	0.703	1.00
320_T	394_I	0.702	1.00
142_E	216_D	0.701	1.00
16_T	35_H	0.699	1.00
357_A	361_L	0.698	1.00
87_V	100_A	0.697	1.00
468_D	471_R	0.697	1.00
486_P	490_D	0.695	1.00
113_E	369_R	0.694	1.00
192_S	253_L	0.693	1.00
259_A	449_T	0.691	1.00
423_V	429_C	0.691	1.00
201_N	206_E	0.690	1.00
367_D	370_A	0.688	0.99
350_D	381_T	0.687	0.99
50_L	96_P	0.685	0.99
458_G	462_G	0.683	0.99
124_I	211_L	0.682	0.99
315_G	401_I	0.682	0.99
327_L	387_V	0.681	0.99
236_H	239_P	0.678	0.99
76_A	248_P	0.676	0.99
60_V	241_G	0.675	0.99
337_A	341_E	0.673	0.99
416_L	438_T	0.670	0.99
180_I	184_T	0.667	0.99
245_A	248_P	0.666	0.99
64_L	69_L	0.665	0.99
57_K	182_N	0.665	0.99
151_L	170_L	0.664	0.99
418_V	440_L	0.664	0.99
351_G	388_R	0.662	0.99
94_G	168_G	0.661	0.99
265_C	272_K	0.660	0.99
224_E	230_D	0.660	0.99
332_L	336_A	0.658	0.99
334_N	339_T	0.655	0.99
333_I	338_Q	0.654	0.99
481_E	484_M	0.654	0.99
58_S	61_T	0.654	0.99
81_N	193_N	0.653	0.99
237_T	242_F	0.652	0.99
56_T	59_V	0.652	0.99
90_D	97_I	0.652	0.99
171_L	181_Y	0.651	0.99
473_N	476_V	0.651	0.99
88_V	97_I	0.650	0.99
6_V	75_A	0.650	0.99
122_E	125_R	0.650	0.99
273_N	416_L	0.650	0.99
60_V	63_G	0.648	0.99
178_W	181_Y	0.647	0.99
11_Q	55_N	0.646	0.99
331_D	334_N	0.645	0.99
228_S	252_A	0.645	0.99
490_D	493_Y	0.644	0.99
128_T	211_L	0.642	0.99
101_L	107_R	0.639	0.99
243_L	246_A	0.637	0.99
344_S	347_D	0.637	0.99
50_L	99_N	0.637	0.99
349_T	385_H	0.637	0.99
317_I	401_I	0.636	0.99
342_L	346_V	0.636	0.99
360_G	363_A	0.634	0.99
365_H	400_D	0.630	0.99
415_T	438_T	0.628	0.99
236_H	248_P	0.628	0.99
227_P	303_Q	0.628	0.99
89_W	178_W	0.627	0.99
243_L	247_V	0.627	0.99
21_F	450_A	0.626	0.99
334_N	383_K	0.625	0.99
237_T	247_V	0.625	0.99
255_D	277_T	0.625	0.99
416_L	440_L	0.625	0.99
177_S	187_H	0.624	0.99
372_G	375_V	0.624	0.99
442_R	477_D	0.623	0.99
23_Q	75_A	0.621	0.99
392_E	431_L	0.621	0.99
296_L	299_T	0.620	0.99
176_D	193_N	0.619	0.99
455_Y	459_L	0.617	0.99
213_E	218_P	0.616	0.99
89_W	181_Y	0.615	0.99
145_L	216_D	0.615	0.99
464_W	473_N	0.614	0.99
467_L	471_R	0.613	0.99
248_P	461_V	0.613	0.99
344_S	426_N	0.613	0.99
279_S	432_Q	0.612	0.99
470_L	473_N	0.612	0.99
109_T	134_A	0.610	0.99
39_Y	45_V	0.609	0.99
82_Q	103_W	0.609	0.99
414_T	438_T	0.608	0.99
141_T	221_M	0.607	0.99
115_L	215_F	0.607	0.99
57_K	241_G	0.606	0.99
426_N	430_Q	0.605	0.99
50_L	53_W	0.604	0.99
142_E	215_F	0.603	0.99
264_T	474_W	0.602	0.99
359_T	379_R	0.602	0.99
335_N	340_A	0.601	0.99
241_G	247_V	0.601	0.99
192_S	228_S	0.600	0.99
254_G	257_Q	0.598	0.99
439_D	482_P	0.598	0.99
358_F	364_P	0.598	0.99
49_P	100_A	0.597	0.99
327_L	330_V	0.596	0.99
388_R	431_L	0.595	0.99
282_L	312_A	0.594	0.99
331_D	383_K	0.593	0.99
54_E	240_D	0.593	0.99
494_G	497_E	0.592	0.98
86_T	137_S	0.592	0.98
57_K	60_V	0.591	0.98
68_G	71_A	0.590	0.98
27_V	445_V	0.590	0.98
352_V	386_I	0.590	0.98
199_L	222_L	0.587	0.98
19_I	27_V	0.587	0.98
132_A	198_M	0.587	0.98
348_T	385_H	0.586	0.98
429_C	442_R	0.585	0.98
81_N	175_I	0.584	0.98
358_F	362_G	0.584	0.98
304_L	307_E	0.584	0.98
320_T	323_A	0.584	0.98
355_V	373_T	0.583	0.98
26_D	444_E	0.582	0.98
186_E	226_R	0.582	0.98
94_G	169_E	0.582	0.98
346_V	384_A	0.580	0.98
238_D	246_A	0.580	0.98
238_D	241_G	0.580	0.98
351_G	385_H	0.579	0.98
349_T	388_R	0.579	0.98
264_T	471_R	0.579	0.98
430_Q	480_F	0.578	0.98
431_L	489_A	0.577	0.98
325_E	328_E	0.577	0.98
88_V	170_L	0.577	0.98
108_T	139_T	0.576	0.98
407_A	497_E	0.576	0.98
265_C	270_D	0.576	0.98
144_L	148_A	0.576	0.98
168_G	220_E	0.575	0.98
347_D	350_D	0.574	0.98
87_V	96_P	0.571	0.98
5_Y	67_A	0.571	0.98
437_Q	484_M	0.568	0.98
101_L	144_L	0.568	0.98
261_F	455_Y	0.567	0.98
115_L	139_T	0.567	0.98
139_T	198_M	0.567	0.98
275_Y	418_V	0.566	0.98
213_E	216_D	0.565	0.98
136_F	196_R	0.565	0.98
343_A	391_L	0.565	0.98
230_D	233_V	0.565	0.98
324_I	339_T	0.565	0.98
203_T	288_D	0.564	0.98
262_G	448_T	0.564	0.98
430_Q	433_S	0.563	0.98
425_N	428_L	0.562	0.98
74_L	243_L	0.562	0.98
365_H	500_V	0.561	0.98
197_T	207_W	0.559	0.98
451_L	455_Y	0.559	0.98
445_V	451_L	0.559	0.98
166_R	169_E	0.558	0.98
46_E	98_H	0.558	0.98
354_M	393_S	0.557	0.98
77_I	237_T	0.557	0.98
256_Q	274_T	0.557	0.98
130_L	136_F	0.557	0.98
281_Y	401_I	0.556	0.98
351_G	392_E	0.555	0.98
344_S	430_Q	0.555	0.98
355_V	500_V	0.553	0.98
350_D	380_G	0.552	0.98
394_I	428_L	0.552	0.98
86_T	144_L	0.551	0.98
468_D	472_E	0.548	0.98
489_A	492_K	0.548	0.98
229_S	460_A	0.548	0.98
365_H	497_E	0.548	0.98
107_R	147_E	0.546	0.97
392_E	396_Y	0.546	0.97
25_G	473_N	0.545	0.97
233_V	461_V	0.545	0.97
301_G	311_Y	0.545	0.97
423_V	442_R	0.545	0.97
336_A	342_L	0.545	0.97
77_I	249_V	0.544	0.97
321_G	325_E	0.544	0.97
48_D	54_E	0.544	0.97
466_S	472_E	0.543	0.97
273_N	281_Y	0.543	0.97
118_N	142_E	0.542	0.97
260_L	282_L	0.542	0.97
413_T	438_T	0.538	0.97
370_A	374_L	0.536	0.97
88_V	98_H	0.536	0.97
340_A	427_F	0.536	0.97
332_L	335_N	0.533	0.97
279_S	317_I	0.532	0.97
349_T	392_E	0.532	0.97
459_L	464_W	0.531	0.97
203_T	206_E	0.530	0.97
336_A	343_A	0.528	0.97
172_M	197_T	0.528	0.97
192_S	257_Q	0.527	0.97
285_T	289_A	0.526	0.97
283_M	413_T	0.525	0.97
6_V	464_W	0.525	0.97
455_Y	474_W	0.525	0.97
217_I	222_L	0.524	0.97
83_R	196_R	0.523	0.97
85_T	102_V	0.522	0.97
228_S	253_L	0.522	0.97
364_P	368_G	0.522	0.97
450_A	453_A	0.522	0.97
96_P	99_N	0.521	0.97
274_T	419_D	0.521	0.97
211_L	215_F	0.519	0.97
433_S	440_L	0.519	0.97
260_L	301_G	0.518	0.97
14_T	17_R	0.518	0.97
343_A	387_V	0.518	0.97
89_W	169_E	0.517	0.96
150_P	166_R	0.517	0.96
80_T	453_A	0.516	0.96
134_A	368_G	0.516	0.96
45_V	102_V	0.515	0.96
348_T	388_R	0.515	0.96
13_T	103_W	0.515	0.96
369_R	372_G	0.514	0.96
171_L	221_M	0.514	0.96
312_A	316_S	0.513	0.96
398_T	432_Q	0.512	0.96
281_Y	398_T	0.510	0.96
459_L	462_G	0.509	0.96
141_T	172_M	0.508	0.96
30_N	66_A	0.507	0.96
277_T	322_A	0.507	0.96
432_Q	436_I	0.506	0.96
360_G	367_D	0.506	0.96
490_D	497_E	0.506	0.96
270_D	414_T	0.506	0.96
363_A	366_W	0.505	0.96
355_V	361_L	0.505	0.96
244_G	248_P	0.504	0.96
237_T	243_L	0.503	0.96
272_K	282_L	0.502	0.96
255_D	421_G	0.501	0.96
310_Q	467_L	0.501	0.96
44_W	101_L	0.501	0.96
369_R	373_T	0.501	0.96
335_N	339_T	0.501	0.96
343_A	388_R	0.500	0.96

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3ezwA	3	0.9667	100	0.144	Contact Map
3g25A	3	0.9667	100	0.152	Contact Map
3ll3A	2	0.9451	100	0.152	Contact Map
2d4wA	2	0.9647	100	0.155	Contact Map
2zf5O	3	0.9569	100	0.157	Contact Map
3h3nX	3	0.9686	100	0.157	Contact Map
3wxlA	2	0.9647	100	0.159	Contact Map
2dpnA	2	0.9569	100	0.16	Contact Map
2w40A	3	0.9647	100	0.175	Contact Map
2itmA	2	0.9196	100	0.178	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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