Q9HNR0 - HALSA - GREMLIN Contacts

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Q9HNR0 - Protein-export membrane protein SecD

UniProt:	Q9HNR0	Sequences: MSWFRENWRIAALVVLVVASSVALFAPGIGASANTSGQQAATGDPTNLNYGLELSGGVRLRTTVTGVTADGVSVTPDNEGEIATRISTALDVDRGDVRARPATGSVEVYQNVSTSSLRTTLEDAGYSPDSVRRGVTQATRDNIVSIIGSKIDATGLGGAEVKDIETSAGAQAHYIVVEVPGQNASQVQSLIQGRGQVTLDAYYPGSNGTNVNATVLRGDELVEVDQPKRDQNGRPFVPVQLSAEAAQRFTGDMTQYGFTSQAGISNCRFPNGGYCLLTKLDGEEVYNASMGPTLARTLSSGKFVNNPSFRITANSMTAARNLQVNLQAGALPAEITVQNSYYVAPSFAQKYKPLSLVTGLAAAIAVAIMVLLRYGEPKIAIPMVFTALAEVVILLGFAAVSGLALDLSHLAGFIAVIGTGVDDLVIIADEVMTEQVSSSRIFQSRFRKALWVIGAAAATTILAMSPLAVLSLGDLRGFALVTILGVLIGVLVTRPAYGDVLRRLLTTDT	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	509 (458)
Sequences:	2298 (1591)
Seq/√Len:	74.3

ECOLI - SECD MDTB MDTC ACRD ACRB MDTF ACRF CUSA
BACSU - SWRC
HALSA - Q9HNR0

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
349_Q	353_P	6.196	1.00
397_F	484_L	5.587	1.00
380_A	383_M	5.335	1.00
381_I	384_V	4.697	1.00
380_A	384_V	4.630	1.00
230_D	234_R	4.602	1.00
378_K	381_I	4.534	1.00
20_S	393_I	4.327	1.00
380_A	387_A	3.907	1.00
378_K	384_V	3.739	1.00
227_P	238_P	3.658	1.00
239_V	303_F	3.463	1.00
378_K	382_P	3.452	1.00
378_K	383_M	3.366	1.00
63_T	173_H	3.284	1.00
461_I	483_I	3.268	1.00
220_E	242_S	3.230	1.00
490_V	494_R	3.224	1.00
381_I	387_A	3.200	1.00
378_K	387_A	3.043	1.00
419_T	460_T	2.997	1.00
384_V	387_A	2.986	1.00
272_G	292_P	2.956	1.00
380_A	386_T	2.953	1.00
291_G	306_N	2.886	1.00
101_P	104_G	2.860	1.00
383_M	387_A	2.856	1.00
271_N	274_Y	2.847	1.00
206_S	209_T	2.840	1.00
381_I	385_F	2.836	1.00
379_I	383_M	2.773	1.00
137_Q	163_D	2.756	1.00
236_F	304_V	2.743	1.00
379_I	382_P	2.728	1.00
389_A	496_A	2.678	1.00
185_S	189_S	2.618	1.00
251_G	255_Q	2.596	1.00
104_G	107_E	2.452	1.00
360_L	364_I	2.446	1.00
383_M	386_T	2.434	1.00
431_V	442_F	2.389	1.00
234_R	291_G	2.376	1.00
201_A	252_D	2.235	1.00
236_F	306_N	2.232	1.00
11_A	15_V	2.227	1.00
216_L	248_R	2.188	1.00
13_L	496_A	2.131	1.00
186_Q	321_N	2.122	1.00
28_G	399_A	2.084	1.00
381_I	386_T	2.053	1.00
382_P	387_A	2.048	1.00
188_Q	340_S	2.039	1.00
378_K	385_F	2.028	1.00
394_L	484_L	2.020	1.00
428_A	464_M	2.017	1.00
254_T	297_T	2.001	1.00
203_Y	211_V	2.001	1.00
17_V	389_A	1.981	1.00
450_L	454_G	1.963	1.00
457_A	490_V	1.908	1.00
380_A	385_F	1.905	1.00
431_V	445_R	1.861	1.00
64_V	333_A	1.846	1.00
240_Q	302_K	1.841	1.00
464_M	482_T	1.828	1.00
215_V	252_D	1.817	1.00
40_A	44_D	1.802	1.00
273_G	291_G	1.782	1.00
298_L	303_F	1.781	1.00
361_A	365_A	1.771	1.00
359_G	417_I	1.759	1.00
68_T	71_G	1.741	1.00
382_P	386_T	1.741	1.00
423_D	489_G	1.741	1.00
379_I	384_V	1.737	1.00
148_G	152_D	1.725	1.00
154_T	190_L	1.704	1.00
38_Q	42_T	1.696	1.00
182_Q	187_V	1.693	1.00
444_S	448_K	1.679	1.00
84_T	88_T	1.675	1.00
363_A	391_V	1.666	1.00
464_M	483_I	1.655	1.00
428_A	482_T	1.647	1.00
419_T	482_T	1.645	1.00
15_V	19_A	1.617	1.00
107_E	110_Q	1.600	0.99
442_F	505_L	1.595	0.99
357_V	361_A	1.591	0.99
382_P	385_F	1.589	0.99
483_I	487_L	1.583	0.99
204_P	275_C	1.574	0.99
105_S	109_Y	1.566	0.99
378_K	386_T	1.549	0.99
183_N	186_Q	1.499	0.99
26_A	29_I	1.493	0.99
216_L	220_E	1.481	0.99
489_G	494_R	1.480	0.99
466_P	470_L	1.472	0.99
250_T	299_S	1.466	0.99
410_L	414_I	1.448	0.99
16_L	19_A	1.436	0.99
277_L	280_L	1.433	0.99
24_L	29_I	1.428	0.99
379_I	387_A	1.416	0.99
454_G	458_A	1.415	0.99
298_L	301_G	1.411	0.99
278_T	286_Y	1.408	0.99
134_G	138_A	1.407	0.99
303_F	309_F	1.383	0.98
309_F	315_S	1.374	0.98
227_P	236_F	1.356	0.98
494_R	497_Y	1.349	0.98
364_I	368_I	1.344	0.98
425_V	482_T	1.337	0.98
291_G	304_V	1.335	0.98
115_S	118_R	1.334	0.98
99_A	108_V	1.329	0.98
186_Q	189_S	1.326	0.98
448_K	451_W	1.322	0.98
112_V	121_L	1.322	0.98
359_G	410_L	1.312	0.98
112_V	115_S	1.307	0.98
73_S	77_D	1.296	0.98
37_G	40_A	1.281	0.97
292_P	306_N	1.266	0.97
463_A	466_P	1.259	0.97
353_P	357_V	1.255	0.97
199_L	305_N	1.243	0.97
292_P	297_T	1.241	0.97
394_L	488_I	1.237	0.97
238_P	304_V	1.230	0.97
104_G	108_V	1.218	0.96
416_V	485_G	1.214	0.96
272_G	277_L	1.214	0.96
422_D	459_T	1.213	0.96
10_I	14_V	1.208	0.96
366_V	417_I	1.198	0.96
431_V	460_T	1.198	0.96
286_Y	322_L	1.195	0.96
132_R	136_T	1.194	0.96
306_N	309_F	1.190	0.96
137_Q	141_D	1.184	0.96
350_K	354_L	1.178	0.96
184_A	192_Q	1.173	0.96
223_E	240_Q	1.166	0.95
19_A	400_V	1.156	0.95
446_F	501_L	1.153	0.95
228_K	235_P	1.151	0.95
285_V	325_N	1.145	0.95
288_A	301_G	1.142	0.95
10_I	15_V	1.136	0.95
440_R	444_S	1.128	0.95
273_G	277_L	1.126	0.95
82_I	88_T	1.126	0.95
271_N	277_L	1.114	0.94
189_S	321_N	1.109	0.94
80_G	213_A	1.105	0.94
68_T	334_E	1.102	0.94
59_R	160_E	1.102	0.94
285_V	288_A	1.100	0.94
415_A	445_R	1.099	0.94
359_G	414_I	1.096	0.94
39_Q	43_G	1.089	0.93
39_Q	42_T	1.085	0.93
133_R	137_Q	1.080	0.93
244_E	248_R	1.071	0.93
102_A	106_V	1.068	0.93
303_F	308_S	1.066	0.93
275_C	289_S	1.064	0.93
417_I	428_A	1.062	0.93
371_L	379_I	1.062	0.93
228_K	316_M	1.061	0.93
359_G	362_A	1.058	0.92
453_I	489_G	1.057	0.92
246_A	249_F	1.052	0.92
405_L	408_S	1.052	0.92
272_G	297_T	1.051	0.92
379_I	386_T	1.048	0.92
413_F	433_T	1.048	0.92
299_S	303_F	1.048	0.92
272_G	275_C	1.047	0.92
203_Y	208_G	1.047	0.92
20_S	24_L	1.040	0.92
386_T	497_Y	1.038	0.92
120_T	125_G	1.035	0.92
156_L	179_V	1.034	0.92
324_V	327_Q	1.031	0.91
109_Y	113_S	1.029	0.91
289_S	292_P	1.028	0.91
286_Y	300_S	1.024	0.91
99_A	104_G	1.023	0.91
131_V	134_G	1.020	0.91
422_D	430_E	1.018	0.91
366_V	418_G	1.006	0.90
204_P	441_I	1.004	0.90
85_R	88_T	1.001	0.90
67_V	70_D	0.999	0.90
58_V	63_T	0.998	0.90
66_G	136_T	0.996	0.90
456_A	494_R	0.990	0.90
70_D	136_T	0.984	0.89
58_V	184_A	0.982	0.89
36_S	42_T	0.980	0.89
106_V	110_Q	0.979	0.89
246_A	250_T	0.978	0.89
277_L	288_A	0.976	0.89
224_V	323_Q	0.975	0.89
190_L	324_V	0.973	0.89
187_V	335_I	0.972	0.89
422_D	475_L	0.969	0.89
13_L	16_L	0.968	0.89
67_V	72_V	0.967	0.89
89_A	107_E	0.966	0.89
65_T	68_T	0.965	0.89
250_T	297_T	0.962	0.88
449_A	453_I	0.956	0.88
274_Y	277_L	0.952	0.88
246_A	301_G	0.951	0.88
465_S	483_I	0.951	0.88
272_G	276_L	0.945	0.87
419_T	464_M	0.942	0.87
374_Y	415_A	0.936	0.87
359_G	363_A	0.935	0.87
38_Q	41_A	0.929	0.87
96_D	100_R	0.928	0.86
105_S	108_V	0.927	0.86
216_L	250_T	0.920	0.86
19_A	23_A	0.918	0.86
394_L	417_I	0.917	0.86
443_Q	447_R	0.910	0.85
428_A	450_L	0.906	0.85
419_T	428_A	0.894	0.84
425_V	464_M	0.892	0.84
394_L	463_A	0.892	0.84
14_V	18_V	0.890	0.84
419_T	425_V	0.889	0.84
423_D	457_A	0.889	0.84
51_G	54_L	0.887	0.84
74_V	78_N	0.885	0.84
16_L	26_A	0.881	0.84
202_Y	287_N	0.880	0.83
499_D	502_R	0.878	0.83
12_A	16_L	0.875	0.83
104_G	111_N	0.872	0.83
78_N	85_R	0.868	0.83
22_V	43_G	0.867	0.83
102_A	105_S	0.866	0.82
468_A	476_R	0.862	0.82
362_A	367_A	0.861	0.82
95_G	100_R	0.861	0.82
414_I	428_A	0.859	0.82
404_A	407_L	0.858	0.82
276_L	279_K	0.856	0.82
303_F	306_N	0.856	0.82
398_A	402_G	0.851	0.81
120_T	124_A	0.851	0.81
112_V	117_L	0.849	0.81
203_Y	206_S	0.845	0.81
412_G	481_V	0.844	0.81
438_S	441_I	0.837	0.80
300_S	305_N	0.836	0.80
43_G	46_T	0.833	0.80
39_Q	47_N	0.833	0.80
464_M	497_Y	0.831	0.80
230_D	236_F	0.830	0.80
412_G	421_V	0.829	0.80
39_Q	44_D	0.829	0.80
239_V	246_A	0.828	0.80
9_R	13_L	0.827	0.79
231_Q	234_R	0.827	0.79
416_V	460_T	0.826	0.79
271_N	276_L	0.825	0.79
106_V	109_Y	0.824	0.79
15_V	18_V	0.824	0.79
91_D	94_R	0.821	0.79
59_R	339_N	0.820	0.79
278_T	281_D	0.819	0.79
138_A	142_N	0.811	0.78
18_V	22_V	0.810	0.78
405_L	409_H	0.805	0.78
113_S	117_L	0.804	0.78
367_A	470_L	0.802	0.77
414_I	420_G	0.802	0.77
272_G	299_S	0.802	0.77
391_V	490_V	0.798	0.77
398_A	403_L	0.797	0.77
367_A	371_L	0.796	0.77
16_L	393_I	0.794	0.77
63_T	338_Q	0.793	0.77
416_V	488_I	0.792	0.76
37_G	47_N	0.792	0.76
69_A	139_T	0.790	0.76
356_L	360_L	0.790	0.76
414_I	444_S	0.787	0.76
419_T	486_V	0.787	0.76
44_D	47_N	0.787	0.76
429_D	453_I	0.786	0.76
41_A	45_P	0.785	0.76
24_L	28_G	0.784	0.76
36_S	47_N	0.782	0.76
10_I	13_L	0.781	0.75
393_I	397_F	0.779	0.75
371_L	384_V	0.778	0.75
37_G	42_T	0.778	0.75
448_K	463_A	0.778	0.75
30_G	35_T	0.777	0.75
444_S	447_R	0.777	0.75
114_T	122_E	0.775	0.75
438_S	444_S	0.775	0.75
492_V	497_Y	0.773	0.75
45_P	66_G	0.773	0.75
78_N	82_I	0.772	0.75
309_F	322_L	0.771	0.75
151_I	159_A	0.770	0.74
414_I	456_A	0.767	0.74
179_V	187_V	0.767	0.74
69_A	136_T	0.767	0.74
145_S	148_G	0.766	0.74
457_A	462_L	0.765	0.74
430_E	434_E	0.763	0.74
420_G	489_G	0.762	0.74
412_G	453_I	0.762	0.74
446_F	489_G	0.761	0.74
16_L	496_A	0.757	0.73
241_L	303_F	0.756	0.73
249_F	303_F	0.756	0.73
366_V	370_V	0.751	0.73
49_N	402_G	0.748	0.72
35_T	41_A	0.747	0.72
109_Y	112_V	0.747	0.72
380_A	504_L	0.745	0.72
18_V	38_Q	0.745	0.72
36_S	44_D	0.744	0.72
412_G	482_T	0.743	0.72
398_A	418_G	0.743	0.72
68_T	72_V	0.742	0.72
460_T	483_I	0.742	0.72
404_A	408_S	0.742	0.72
475_L	480_L	0.742	0.72
203_Y	209_T	0.742	0.72
430_E	433_T	0.741	0.72
279_K	287_N	0.739	0.71
11_A	14_V	0.737	0.71
396_G	400_V	0.737	0.71
228_K	234_R	0.737	0.71
349_Q	368_I	0.734	0.71
71_G	364_I	0.734	0.71
450_L	494_R	0.733	0.71
10_I	23_A	0.731	0.71
19_A	46_T	0.728	0.70
297_T	300_S	0.728	0.70
223_E	327_Q	0.728	0.70
280_L	288_A	0.728	0.70
46_T	49_N	0.726	0.70
317_T	320_R	0.725	0.70
222_V	240_Q	0.722	0.70
415_A	455_A	0.720	0.69
132_R	221_L	0.720	0.69
119_T	125_G	0.719	0.69
70_D	139_T	0.718	0.69
373_R	458_A	0.718	0.69
20_S	28_G	0.717	0.69
88_T	124_A	0.717	0.69
411_A	478_F	0.713	0.69
37_G	41_A	0.713	0.69
23_A	362_A	0.713	0.69
415_A	422_D	0.712	0.69
460_T	482_T	0.711	0.68
382_P	501_L	0.711	0.68
118_R	123_D	0.709	0.68
153_A	327_Q	0.708	0.68
151_I	156_L	0.708	0.68
456_A	464_M	0.705	0.68
69_A	346_S	0.705	0.68
228_K	233_G	0.702	0.67
287_N	301_G	0.702	0.67
144_V	148_G	0.700	0.67
308_S	315_S	0.697	0.67
200_D	214_T	0.697	0.67
92_V	108_V	0.696	0.67
393_I	488_I	0.696	0.67
15_V	110_Q	0.694	0.67
93_D	493_T	0.693	0.66
280_L	298_L	0.692	0.66
216_L	252_D	0.692	0.66
37_G	44_D	0.689	0.66
211_V	215_V	0.688	0.66
211_V	274_Y	0.686	0.66
119_T	126_Y	0.685	0.66
284_E	287_N	0.685	0.66
51_G	56_G	0.684	0.65
431_V	441_I	0.682	0.65
249_F	298_L	0.681	0.65
460_T	480_L	0.679	0.65
93_D	96_D	0.679	0.65
355_S	452_V	0.679	0.65
18_V	109_Y	0.678	0.65
387_A	445_R	0.677	0.65
238_P	302_K	0.675	0.64
111_N	115_S	0.675	0.64
499_D	503_R	0.674	0.64
23_A	45_P	0.673	0.64
359_G	391_V	0.667	0.63
151_I	187_V	0.666	0.63
366_V	463_A	0.666	0.63
457_A	488_I	0.665	0.63
91_D	96_D	0.664	0.63
286_Y	291_G	0.661	0.63
272_G	280_L	0.660	0.63
10_I	21_S	0.659	0.63
380_A	501_L	0.656	0.62
83_A	87_S	0.655	0.62
120_T	126_Y	0.653	0.62
401_S	484_L	0.653	0.62
81_E	84_T	0.653	0.62
382_P	500_V	0.652	0.62
18_V	103_T	0.651	0.62
222_V	242_S	0.650	0.61
219_D	240_Q	0.649	0.61
155_G	161_V	0.649	0.61
120_T	123_D	0.648	0.61
446_F	497_Y	0.648	0.61
143_I	332_P	0.647	0.61
216_L	232_N	0.646	0.61
371_L	382_P	0.646	0.61
289_S	306_N	0.645	0.61
111_N	114_T	0.645	0.61
428_A	446_F	0.644	0.61
406_D	409_H	0.643	0.61
456_A	475_L	0.643	0.61
375_G	417_I	0.642	0.61
389_A	503_R	0.642	0.61
457_A	461_I	0.640	0.60
54_L	57_G	0.639	0.60
41_A	44_D	0.639	0.60
155_G	326_L	0.638	0.60
422_D	460_T	0.638	0.60
420_G	493_T	0.634	0.60
121_L	124_A	0.633	0.59
426_I	456_A	0.633	0.59
250_T	298_L	0.633	0.59
30_G	47_N	0.633	0.59
199_L	253_M	0.632	0.59
201_A	276_L	0.631	0.59
305_N	308_S	0.631	0.59
16_L	20_S	0.631	0.59
380_A	427_I	0.630	0.59
40_A	60_L	0.630	0.59
40_A	45_P	0.629	0.59
346_S	373_R	0.629	0.59
95_G	99_A	0.628	0.59
338_Q	413_F	0.628	0.59
48_L	395_L	0.627	0.59
111_N	116_S	0.626	0.59
118_R	125_G	0.626	0.59
422_D	455_A	0.624	0.58
118_R	131_V	0.624	0.58
292_P	299_S	0.621	0.58
410_L	462_L	0.620	0.58
297_T	303_F	0.620	0.58
235_P	238_P	0.619	0.58
130_S	134_G	0.619	0.58
288_A	291_G	0.619	0.58
321_N	324_V	0.619	0.58
66_G	69_A	0.619	0.58
72_V	196_Q	0.618	0.58
101_P	105_S	0.618	0.58
414_I	464_M	0.618	0.58
70_D	132_R	0.617	0.57
468_A	480_L	0.617	0.57
365_A	418_G	0.617	0.57
214_T	217_R	0.616	0.57
113_S	120_T	0.615	0.57
254_T	299_S	0.613	0.57
14_V	19_A	0.612	0.57
343_V	463_A	0.612	0.57
145_S	196_Q	0.611	0.57
370_V	382_P	0.611	0.57
249_F	301_G	0.610	0.57
96_D	101_P	0.608	0.56
21_S	91_D	0.608	0.56
211_V	225_D	0.607	0.56
385_F	500_V	0.606	0.56
367_A	488_I	0.606	0.56
303_F	307_P	0.605	0.56
374_Y	432_M	0.604	0.56
95_G	98_R	0.602	0.56
68_T	75_T	0.601	0.56
85_R	89_A	0.600	0.55
476_R	480_L	0.600	0.55
457_A	493_T	0.600	0.55
359_G	369_M	0.600	0.55
457_A	486_V	0.599	0.55
364_I	367_A	0.599	0.55
13_L	22_V	0.599	0.55
36_S	39_Q	0.598	0.55
81_E	85_R	0.598	0.55
73_S	276_L	0.597	0.55
79_E	95_G	0.596	0.55
219_D	244_E	0.596	0.55
459_T	478_F	0.595	0.55
180_P	407_L	0.594	0.55
203_Y	207_N	0.594	0.55
278_T	288_A	0.593	0.55
201_A	215_V	0.593	0.55
457_A	489_G	0.592	0.54
371_L	391_V	0.591	0.54
112_V	119_T	0.591	0.54
105_S	125_G	0.590	0.54
370_V	421_V	0.590	0.54
13_L	499_D	0.589	0.54
240_Q	243_A	0.589	0.54
374_Y	478_F	0.588	0.54
428_A	489_G	0.587	0.54
141_D	163_D	0.587	0.54
59_R	458_A	0.586	0.54
160_E	176_V	0.586	0.54
362_A	366_V	0.585	0.54
73_S	221_L	0.585	0.54
215_V	476_R	0.584	0.53
66_G	140_R	0.584	0.53
357_V	366_V	0.584	0.53
20_S	23_A	0.580	0.53
23_A	400_V	0.580	0.53
241_L	249_F	0.578	0.53
91_D	101_P	0.578	0.53
83_A	90_L	0.578	0.53
351_Y	471_S	0.576	0.52
456_A	483_I	0.576	0.52
63_T	239_V	0.575	0.52
398_A	450_L	0.574	0.52
192_Q	221_L	0.574	0.52
464_M	488_I	0.573	0.52
14_V	371_L	0.573	0.52
239_V	245_A	0.570	0.52
35_T	38_Q	0.570	0.52
230_D	398_A	0.569	0.52
363_A	469_V	0.569	0.52
35_T	39_Q	0.569	0.52
315_S	318_A	0.568	0.51
10_I	503_R	0.567	0.51
359_G	366_V	0.567	0.51
404_A	415_A	0.566	0.51
13_L	82_I	0.566	0.51
449_A	478_F	0.565	0.51
152_D	161_V	0.564	0.51
91_D	363_A	0.564	0.51
40_A	47_N	0.563	0.51
278_T	298_L	0.563	0.51
186_Q	337_V	0.561	0.51
424_L	455_A	0.561	0.51
428_A	466_P	0.561	0.51
458_A	462_L	0.560	0.50
288_A	298_L	0.560	0.50
247_Q	251_G	0.559	0.50
451_W	456_A	0.558	0.50
109_Y	121_L	0.557	0.50
175_I	181_G	0.557	0.50
323_Q	327_Q	0.556	0.50
98_R	103_T	0.556	0.50
12_A	21_S	0.555	0.50
20_S	27_P	0.555	0.50
227_P	304_V	0.554	0.50
440_R	483_I	0.554	0.50
473_G	477_G	0.554	0.50
272_G	289_S	0.554	0.50
416_V	419_T	0.552	0.49
65_T	80_G	0.551	0.49
232_N	235_P	0.550	0.49
101_P	360_L	0.550	0.49
18_V	21_S	0.550	0.49
117_L	125_G	0.549	0.49
37_G	45_P	0.549	0.49
348_A	415_A	0.548	0.49
460_T	464_M	0.548	0.49
10_I	499_D	0.548	0.49
88_T	487_L	0.548	0.49
117_L	120_T	0.548	0.49
403_L	407_L	0.547	0.49
90_L	107_E	0.547	0.49
251_G	254_T	0.547	0.49
285_V	299_S	0.547	0.49
100_R	108_V	0.546	0.49
220_E	244_E	0.546	0.49
389_A	456_A	0.546	0.49
102_A	108_V	0.546	0.49
61_R	164_I	0.545	0.49
10_I	22_V	0.544	0.48
359_G	483_I	0.544	0.48
74_V	205_G	0.544	0.48
286_Y	309_F	0.544	0.48
302_K	305_N	0.544	0.48
67_V	367_A	0.543	0.48
398_A	452_V	0.543	0.48
133_R	140_R	0.543	0.48
464_M	474_D	0.542	0.48
59_R	176_V	0.541	0.48
363_A	388_L	0.541	0.48
250_T	254_T	0.540	0.48
398_A	415_A	0.540	0.48
10_I	45_P	0.540	0.48
129_D	133_R	0.540	0.48
151_I	162_K	0.540	0.48
387_A	390_E	0.540	0.48
390_E	455_A	0.539	0.48
211_V	255_Q	0.539	0.48
225_D	238_P	0.539	0.48
95_G	101_P	0.538	0.48
199_L	322_L	0.538	0.48
357_V	417_I	0.538	0.48
373_R	422_D	0.537	0.48
417_I	480_L	0.535	0.47
103_T	106_V	0.535	0.47
23_A	43_G	0.535	0.47
105_S	110_Q	0.534	0.47
15_V	124_A	0.534	0.47
213_A	465_S	0.534	0.47
178_E	342_Y	0.533	0.47
149_S	198_T	0.533	0.47
11_A	368_I	0.533	0.47
21_S	26_A	0.531	0.47
461_I	487_L	0.531	0.47
450_L	501_L	0.530	0.47
22_V	71_G	0.530	0.47
358_T	425_V	0.530	0.47
446_F	478_F	0.530	0.47
359_G	448_K	0.529	0.47
124_A	127_S	0.529	0.47
17_V	98_R	0.528	0.46
275_C	287_N	0.527	0.46
153_A	328_A	0.527	0.46
191_I	435_Q	0.527	0.46
246_A	253_M	0.526	0.46
150_K	181_G	0.526	0.46
288_A	303_F	0.526	0.46
82_I	95_G	0.524	0.46
63_T	67_V	0.522	0.46
358_T	479_A	0.521	0.46
291_G	297_T	0.520	0.45
50_Y	54_L	0.520	0.45
279_K	283_E	0.520	0.45
22_V	40_A	0.519	0.45
411_A	455_A	0.519	0.45
326_L	479_A	0.518	0.45
77_D	80_G	0.517	0.45
441_I	489_G	0.517	0.45
109_Y	123_D	0.516	0.45
18_V	92_V	0.515	0.45
20_S	26_A	0.514	0.45
12_A	26_A	0.514	0.45
174_Y	358_T	0.514	0.45
18_V	37_G	0.513	0.45
54_L	58_V	0.512	0.44
50_Y	352_K	0.512	0.44
96_D	251_G	0.512	0.44
69_A	135_V	0.512	0.44
155_G	345_P	0.512	0.44
120_T	436_V	0.511	0.44
97_V	368_I	0.510	0.44
12_A	23_A	0.510	0.44
379_I	385_F	0.509	0.44
96_D	104_G	0.508	0.44
73_S	78_N	0.508	0.44
164_I	176_V	0.508	0.44
235_P	369_M	0.508	0.44
478_F	489_G	0.506	0.44
249_F	253_M	0.506	0.44
353_P	356_L	0.506	0.44
301_G	309_F	0.506	0.44
63_T	336_T	0.506	0.44
36_S	40_A	0.505	0.44
426_I	460_T	0.504	0.43
241_L	252_D	0.504	0.43
271_N	280_L	0.504	0.43
102_A	127_S	0.504	0.43
16_L	23_A	0.504	0.43
154_T	285_V	0.504	0.43
352_K	420_G	0.503	0.43
187_V	490_V	0.503	0.43
59_R	65_T	0.502	0.43
19_A	122_E	0.502	0.43
159_A	321_N	0.502	0.43
14_V	24_L	0.501	0.43
147_I	404_A	0.501	0.43
67_V	134_G	0.500	0.43
245_A	328_A	0.500	0.43

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3aqpA	1	0.776	100	0.395	Contact Map
4k0jA	3	0.8978	100	0.473	Contact Map
3w9iA	3	0.9018	100	0.49	Contact Map
3ne5A	3	0.9077	100	0.495	Contact Map
4mt1A	3	0.8939	100	0.502	Contact Map
4dx5A	3	0.9018	100	0.505	Contact Map
3aqoA	1	0.3772	99.9	0.764	Contact Map
4r86A	1	0.501	98.2	0.9	Contact Map
4ea3A	2	0.5147	14	0.97	Contact Map
1in0A	1	0.3143	12.8	0.971	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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