IF2P - HALSA - GREMLIN Contacts

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IF2P - Probable translation initiation factor IF-2

UniProt:	Q9HNQ2	Sequences: MPDADTTDDPGDLRTPIVAVLGHVDHGKTSLLDKIRGSAVIEGEAGAITQHIGATAVPLDTVSEVAGSLVDPTEFDLPGLLFIDTPGHHSFSTLRSRGGALADIAILVVDVNDGFQPQTEEAIRILKDTGTPFVVAANKIDTTPGWNPNPDAPVQGTYDDQSDRVRSDLDDALYELIGEMSDAGFSSDLYWRVQNFQKNVGVIPVSAETGEGVPDLLTVLMGLAQRYMKSEMEVTIDGPGAGTVLEVKDEQGFGTTVDVILYDGTIRSGDTVVVGAQPEPIVTDVRALLKPGDLAEMRTEKRFGNVDRMQAAAGLKVAAPDLDDAMAGAPIRVVGDRDVADVVTEVEAELAEVAVETGEEGIVVKADTLGSLEALVSALEEAEIPVMSAEVGDVAPRDVAMATTVDSEKHRVLLGFNVDVLPAAAENAERESVRVFNSDVIYQLVEDYEAFVDAQEREQKEAVFDNIVRPARFRILKDHVFRQNDPAVVGVEVVSGTLKRNTPVGGIEGNDLDRAGIVKGIQDQGEDVDEARAGNRVSVSIDGPTVGRDIKEGDELWVDLPEKHAKVLDQELTSDLPADEREALKSYLDIMRKRDPFWGK	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	600 (493)
Sequences:	3565 (1756)
Seq/√Len:	79.1

ECOLI - IF2
BACSU - IF2
HALSA - IF2P
SULSO - IF2P

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
106_I	220_L	5.230	1.00
78_P	225_Q	4.079	1.00
286_R	290_K	4.057	1.00
366_A	372_L	3.606	1.00
34_K	210_G	3.526	1.00
201_G	219_V	3.454	1.00
295_A	301_K	3.334	1.00
503_P	517_I	3.312	1.00
517_I	542_D	3.297	1.00
466_N	562_E	3.255	1.00
399_V	413_L	3.222	1.00
515_A	559_D	3.221	1.00
34_K	213_V	3.191	1.00
394_V	415_G	3.096	1.00
350_L	353_V	2.922	1.00
479_H	552_E	2.891	1.00
212_G	215_D	2.875	1.00
348_A	351_A	2.871	1.00
375_L	444_L	2.852	1.00
267_R	294_L	2.749	1.00
347_E	350_L	2.718	1.00
223_L	230_S	2.718	1.00
166_R	195_N	2.684	1.00
120_E	189_L	2.676	1.00
348_A	353_V	2.654	1.00
497_T	532_R	2.641	1.00
277_Q	308_R	2.572	1.00
474_R	492_E	2.554	1.00
166_R	204_P	2.546	1.00
112_N	142_T	2.535	1.00
37_G	210_G	2.431	1.00
345_E	349_E	2.420	1.00
468_V	502_T	2.418	1.00
449_E	453_D	2.411	1.00
346_V	349_E	2.384	1.00
499_K	560_L	2.366	1.00
506_G	541_I	2.336	1.00
346_V	350_L	2.313	1.00
443_Q	446_E	2.302	1.00
347_E	353_V	2.292	1.00
120_E	124_R	2.259	1.00
137_A	202_V	2.230	1.00
428_A	435_V	2.187	1.00
480_V	487_A	2.186	1.00
126_L	133_F	2.180	1.00
101_L	243_T	2.156	1.00
124_R	388_S	2.153	1.00
51_H	368_T	2.150	1.00
238_G	263_D	2.136	1.00
349_E	353_V	2.125	1.00
520_G	540_S	2.110	1.00
345_E	348_A	2.100	1.00
518_V	539_V	2.075	1.00
463_V	561_P	2.067	1.00
347_E	352_E	2.065	1.00
348_A	352_E	2.046	1.00
58_P	79_G	2.013	1.00
346_V	353_V	2.009	1.00
56_A	79_G	2.003	1.00
438_S	447_D	1.996	1.00
446_E	449_E	1.992	1.00
346_V	352_E	1.983	1.00
35_I	213_V	1.979	1.00
347_E	351_A	1.972	1.00
528_V	531_A	1.947	1.00
107_L	135_V	1.946	1.00
483_Q	540_S	1.946	1.00
470_P	495_S	1.916	1.00
13_L	78_P	1.904	1.00
137_A	204_P	1.866	1.00
344_T	348_A	1.857	1.00
321_D	324_D	1.848	1.00
522_Q	527_D	1.842	1.00
138_N	207_A	1.831	1.00
194_Q	201_G	1.826	1.00
296_E	299_T	1.821	1.00
134_V	220_L	1.815	1.00
344_T	347_E	1.799	1.00
492_E	536_R	1.786	1.00
507_I	512_L	1.774	1.00
193_V	202_V	1.766	1.00
473_F	487_A	1.737	1.00
466_N	560_L	1.732	1.00
498_L	539_V	1.732	1.00
204_P	211_E	1.732	1.00
164_R	168_D	1.697	1.00
168_D	171_D	1.695	1.00
403_T	431_E	1.693	1.00
140_I	211_E	1.677	1.00
349_E	352_E	1.674	1.00
10_P	237_D	1.655	1.00
426_E	429_E	1.637	1.00
35_I	217_L	1.626	1.00
342_V	346_V	1.624	1.00
344_T	350_L	1.615	1.00
56_A	81_L	1.612	1.00
170_D	196_F	1.608	1.00
494_V	555_E	1.600	1.00
108_V	205_V	1.590	1.00
498_L	558_V	1.584	1.00
165_V	169_L	1.583	1.00
210_G	213_V	1.582	1.00
272_V	306_V	1.579	1.00
147_N	167_S	1.544	0.99
114_G	168_D	1.537	0.99
415_G	437_N	1.528	0.99
523_D	531_A	1.526	0.99
259_V	316_K	1.524	0.99
519_K	542_D	1.523	0.99
170_D	192_R	1.520	0.99
136_A	205_V	1.518	0.99
471_A	498_L	1.515	0.99
502_T	558_V	1.510	0.99
472_R	553_G	1.508	0.99
203_I	219_V	1.493	0.99
193_V	200_V	1.484	0.99
166_R	169_L	1.472	0.99
343_V	347_E	1.468	0.99
34_K	209_T	1.466	0.99
516_G	541_I	1.465	0.99
504_V	541_I	1.457	0.99
506_G	550_I	1.453	0.99
358_G	457_R	1.452	0.99
506_G	547_G	1.442	0.99
201_G	223_L	1.438	0.99
497_T	530_E	1.433	0.99
503_P	559_D	1.421	0.99
345_E	350_L	1.416	0.99
56_A	299_T	1.416	0.99
345_E	351_A	1.416	0.99
209_T	212_G	1.414	0.99
283_T	304_G	1.409	0.99
363_V	413_L	1.403	0.99
376_V	389_A	1.398	0.99
491_V	537_V	1.380	0.99
255_T	309_M	1.368	0.99
10_P	235_T	1.363	0.99
344_T	353_V	1.361	0.99
19_A	105_A	1.354	0.99
344_T	349_E	1.353	0.99
235_T	238_G	1.338	0.98
127_K	190_Y	1.328	0.98
346_V	351_A	1.322	0.98
344_T	352_E	1.321	0.98
345_E	353_V	1.316	0.98
464_F	564_H	1.316	0.98
426_E	430_R	1.314	0.98
39_A	42_E	1.307	0.98
104_I	134_V	1.297	0.98
414_L	444_L	1.290	0.98
341_D	344_T	1.286	0.98
393_D	510_N	1.280	0.98
170_D	189_L	1.275	0.98
140_I	212_G	1.273	0.98
191_W	200_V	1.270	0.98
471_A	491_V	1.250	0.98
343_V	349_E	1.249	0.98
427_N	431_E	1.248	0.97
468_V	558_V	1.246	0.97
359_E	385_P	1.246	0.97
59_L	78_P	1.244	0.97
12_D	237_D	1.236	0.97
148_P	204_P	1.233	0.97
518_V	541_I	1.232	0.97
240_G	266_I	1.231	0.97
268_S	293_D	1.224	0.97
345_E	352_E	1.212	0.97
491_V	539_V	1.212	0.97
340_A	344_T	1.196	0.97
241_A	263_D	1.196	0.97
235_T	263_D	1.191	0.97
509_G	551_K	1.187	0.97
236_I	265_T	1.182	0.97
12_D	236_I	1.182	0.97
425_A	429_E	1.181	0.96
272_V	316_K	1.167	0.96
239_P	320_P	1.165	0.96
248_K	302_R	1.162	0.96
270_D	318_A	1.161	0.96
523_D	535_N	1.155	0.96
195_N	204_P	1.147	0.96
467_I	495_S	1.146	0.96
499_K	502_T	1.146	0.96
115_F	202_V	1.145	0.96
423_A	426_E	1.141	0.96
133_F	191_W	1.135	0.96
531_A	537_V	1.133	0.96
462_A	564_H	1.131	0.96
507_I	510_N	1.131	0.96
464_F	562_E	1.118	0.95
59_L	77_L	1.115	0.95
504_V	518_V	1.111	0.95
242_G	316_K	1.109	0.95
122_A	125_I	1.106	0.95
473_F	556_L	1.105	0.95
164_R	169_L	1.104	0.95
539_V	556_L	1.102	0.95
443_Q	450_A	1.095	0.95
491_V	518_V	1.091	0.95
249_D	309_M	1.089	0.94
274_V	306_V	1.087	0.94
249_D	255_T	1.086	0.94
290_K	293_D	1.085	0.94
364_V	372_L	1.082	0.94
32_L	82_F	1.082	0.94
419_D	511_D	1.081	0.94
471_A	558_V	1.074	0.94
420_V	437_N	1.071	0.94
262_Y	298_R	1.070	0.94
364_V	444_L	1.069	0.94
295_A	299_T	1.068	0.94
111_V	146_W	1.068	0.94
343_V	350_L	1.067	0.94
381_E	457_R	1.063	0.94
447_D	450_A	1.052	0.93
93_T	377_S	1.052	0.93
245_L	258_D	1.048	0.93
467_I	507_I	1.048	0.93
378_A	445_V	1.046	0.93
30_S	34_K	1.044	0.93
340_A	343_V	1.044	0.93
11_G	235_T	1.043	0.93
495_S	533_A	1.041	0.93
518_V	558_V	1.039	0.93
60_D	78_P	1.039	0.93
166_R	170_D	1.038	0.93
376_V	386_V	1.036	0.93
421_L	424_A	1.034	0.93
30_S	41_I	1.033	0.93
311_A	314_G	1.031	0.93
80_L	220_L	1.029	0.93
532_R	535_N	1.027	0.93
19_A	131_T	1.025	0.92
285_V	291_P	1.024	0.92
487_A	548_R	1.022	0.92
204_P	215_D	1.018	0.92
521_I	539_V	1.017	0.92
515_A	556_L	1.010	0.92
334_V	338_D	1.009	0.92
140_I	204_P	1.007	0.92
453_D	565_A	1.007	0.92
343_V	346_V	1.003	0.92
124_R	127_K	1.003	0.92
341_D	347_E	1.000	0.92
109_V	135_V	0.994	0.91
498_L	518_V	0.991	0.91
17_I	260_I	0.990	0.91
343_V	348_A	0.989	0.91
399_V	435_V	0.985	0.91
414_L	448_Y	0.983	0.91
166_R	202_V	0.983	0.91
341_D	348_A	0.982	0.91
243_T	262_Y	0.982	0.91
292_G	301_K	0.981	0.91
541_I	556_L	0.977	0.91
287_A	292_G	0.976	0.91
468_V	497_T	0.972	0.90
140_I	148_P	0.969	0.90
503_P	561_P	0.969	0.90
208_E	211_E	0.966	0.90
193_V	196_F	0.966	0.90
514_R	551_K	0.966	0.90
361_G	385_P	0.962	0.90
446_E	450_A	0.961	0.90
342_V	348_A	0.959	0.90
39_A	214_P	0.957	0.90
503_P	515_A	0.954	0.90
276_A	333_V	0.949	0.89
149_N	204_P	0.947	0.89
514_R	543_G	0.943	0.89
164_R	167_S	0.936	0.89
276_A	336_D	0.932	0.88
342_V	347_E	0.924	0.88
340_A	348_A	0.924	0.88
341_D	353_V	0.922	0.88
58_P	77_L	0.922	0.88
60_D	77_L	0.921	0.88
273_V	319_A	0.920	0.88
283_T	291_P	0.919	0.88
30_S	208_E	0.917	0.88
439_D	443_Q	0.915	0.87
422_P	425_A	0.915	0.87
523_D	528_V	0.914	0.87
105_A	122_A	0.910	0.87
83_I	93_T	0.910	0.87
492_E	535_N	0.905	0.87
341_D	350_L	0.903	0.87
487_A	550_I	0.901	0.87
213_V	217_L	0.895	0.86
292_G	295_A	0.894	0.86
279_E	306_V	0.890	0.86
467_I	470_P	0.889	0.86
128_D	361_G	0.887	0.86
487_A	541_I	0.886	0.86
440_V	444_L	0.886	0.86
342_V	350_L	0.885	0.86
482_R	487_A	0.884	0.86
57_V	82_F	0.882	0.85
324_D	331_I	0.880	0.85
189_L	192_R	0.880	0.85
372_L	389_A	0.877	0.85
20_V	220_L	0.876	0.85
204_P	212_G	0.874	0.85
463_V	563_K	0.864	0.84
453_D	463_V	0.861	0.84
470_P	494_V	0.855	0.84
219_V	223_L	0.854	0.84
504_V	558_V	0.852	0.83
167_S	170_D	0.852	0.83
341_D	349_E	0.848	0.83
97_R	373_E	0.846	0.83
400_A	403_T	0.845	0.83
171_D	189_L	0.843	0.83
240_G	318_A	0.840	0.83
272_V	281_I	0.838	0.82
45_A	439_D	0.837	0.82
19_A	102_A	0.836	0.82
205_V	209_T	0.831	0.82
360_E	452_V	0.830	0.82
372_L	386_V	0.830	0.82
120_E	123_I	0.829	0.82
514_R	541_I	0.824	0.81
504_V	556_L	0.824	0.81
203_I	215_D	0.822	0.81
415_G	418_V	0.820	0.81
498_L	504_V	0.819	0.81
340_A	351_A	0.818	0.81
519_K	540_S	0.818	0.81
505_G	557_W	0.818	0.81
507_I	511_D	0.816	0.81
252_G	364_V	0.814	0.81
472_R	555_E	0.812	0.80
123_I	127_K	0.810	0.80
436_F	447_D	0.810	0.80
439_D	515_A	0.809	0.80
55_T	81_L	0.807	0.80
473_F	506_G	0.807	0.80
265_T	294_L	0.805	0.80
500_R	527_D	0.800	0.79
331_I	335_G	0.797	0.79
522_Q	528_V	0.797	0.79
364_V	386_V	0.797	0.79
189_L	193_V	0.795	0.79
123_I	189_L	0.794	0.79
468_V	560_L	0.793	0.79
363_V	390_E	0.792	0.79
295_A	298_R	0.791	0.79
268_S	291_P	0.790	0.79
284_D	295_A	0.786	0.78
470_P	555_E	0.785	0.78
491_V	531_A	0.783	0.78
125_I	129_T	0.783	0.78
493_V	498_L	0.783	0.78
242_G	260_I	0.778	0.77
201_G	226_R	0.778	0.77
316_K	319_A	0.777	0.77
399_V	428_A	0.777	0.77
324_D	327_A	0.776	0.77
518_V	556_L	0.776	0.77
371_S	440_V	0.775	0.77
483_Q	487_A	0.774	0.77
55_T	300_E	0.773	0.77
26_H	113_D	0.773	0.77
434_R	451_F	0.772	0.77
18_V	80_L	0.770	0.77
474_R	535_N	0.770	0.77
19_A	132_P	0.767	0.76
203_I	212_G	0.764	0.76
277_Q	307_D	0.762	0.76
341_D	345_E	0.761	0.76
47_A	113_D	0.761	0.76
278_P	307_D	0.760	0.76
17_I	101_L	0.760	0.76
428_A	434_R	0.756	0.75
340_A	347_E	0.756	0.75
440_V	443_Q	0.756	0.75
20_V	55_T	0.756	0.75
83_I	368_T	0.755	0.75
170_D	193_V	0.754	0.75
449_E	463_V	0.751	0.75
436_F	451_F	0.751	0.75
106_I	136_A	0.751	0.75
360_E	455_Q	0.751	0.75
274_V	277_Q	0.750	0.75
330_P	333_V	0.749	0.75
483_Q	486_P	0.748	0.75
44_E	49_T	0.743	0.74
12_D	233_E	0.743	0.74
46_G	49_T	0.743	0.74
244_V	274_V	0.741	0.74
342_V	345_E	0.738	0.74
31_L	213_V	0.738	0.74
272_V	303_F	0.738	0.74
44_E	50_Q	0.737	0.74
146_W	165_V	0.737	0.74
473_F	541_I	0.733	0.73
250_E	256_T	0.732	0.73
40_V	43_G	0.732	0.73
88_H	118_Q	0.732	0.73
167_S	171_D	0.731	0.73
344_T	351_A	0.730	0.73
25_D	88_H	0.730	0.73
252_G	256_T	0.728	0.73
503_P	542_D	0.727	0.73
364_V	376_V	0.726	0.72
379_L	448_Y	0.723	0.72
292_G	299_T	0.723	0.72
335_G	339_V	0.723	0.72
287_A	299_T	0.723	0.72
543_G	547_G	0.722	0.72
23_H	27_G	0.721	0.72
512_L	515_A	0.720	0.72
502_T	560_L	0.718	0.72
17_I	262_Y	0.716	0.71
101_L	245_L	0.715	0.71
372_L	376_V	0.712	0.71
472_R	494_V	0.711	0.71
38_S	245_L	0.711	0.71
149_N	196_F	0.710	0.71
509_G	512_L	0.709	0.71
399_V	424_A	0.708	0.71
165_V	168_D	0.707	0.70
463_V	565_A	0.707	0.70
357_T	383_E	0.706	0.70
295_A	300_E	0.704	0.70
340_A	345_E	0.704	0.70
341_D	352_E	0.703	0.70
15_T	79_G	0.703	0.70
23_H	28_K	0.700	0.70
322_L	326_M	0.699	0.70
285_V	288_L	0.698	0.69
19_A	101_L	0.698	0.69
107_L	169_L	0.697	0.69
51_H	83_I	0.696	0.69
479_H	524_Q	0.695	0.69
319_A	324_D	0.693	0.69
306_V	309_M	0.692	0.69
394_V	420_V	0.691	0.69
393_D	511_D	0.690	0.69
457_R	463_V	0.690	0.69
36_R	40_V	0.689	0.68
342_V	353_V	0.689	0.68
261_L	301_K	0.688	0.68
194_Q	219_V	0.688	0.68
303_F	306_V	0.685	0.68
480_V	488_V	0.683	0.68
104_I	224_A	0.680	0.67
124_R	128_D	0.680	0.67
336_D	339_V	0.679	0.67
241_A	315_L	0.679	0.67
34_K	37_G	0.676	0.67
92_S	404_T	0.676	0.67
399_V	433_V	0.675	0.67
335_G	338_D	0.673	0.67
135_V	200_V	0.673	0.67
324_D	328_G	0.672	0.67
333_V	336_D	0.672	0.67
479_H	483_Q	0.671	0.66
30_S	205_V	0.671	0.66
78_P	221_M	0.670	0.66
513_D	550_I	0.669	0.66
20_V	213_V	0.668	0.66
80_L	221_M	0.667	0.66
501_N	517_I	0.666	0.66
452_V	456_E	0.665	0.66
105_A	126_L	0.665	0.66
341_D	346_V	0.664	0.66
382_A	455_Q	0.664	0.66
125_I	128_D	0.663	0.66
51_H	367_D	0.662	0.65
343_V	353_V	0.662	0.65
438_S	443_Q	0.661	0.65
492_E	523_D	0.660	0.65
238_G	265_T	0.659	0.65
20_V	134_V	0.659	0.65
561_P	564_H	0.659	0.65
402_A	413_L	0.658	0.65
279_E	318_A	0.658	0.65
8_D	13_L	0.654	0.64
39_A	288_L	0.654	0.64
79_G	299_T	0.652	0.64
418_V	563_K	0.652	0.64
328_G	332_R	0.651	0.64
83_I	245_L	0.649	0.64
105_A	223_L	0.649	0.64
30_S	209_T	0.645	0.63
451_F	454_A	0.645	0.63
393_D	421_L	0.644	0.63
15_T	299_T	0.641	0.63
41_I	45_A	0.641	0.63
33_D	36_R	0.640	0.63
111_V	140_I	0.639	0.63
328_G	331_I	0.639	0.63
310_Q	313_A	0.638	0.63
199_N	223_L	0.636	0.62
393_D	419_D	0.636	0.62
473_F	550_I	0.635	0.62
205_V	208_E	0.634	0.62
485_D	488_V	0.633	0.62
421_L	426_E	0.632	0.62
457_R	462_A	0.632	0.62
22_G	28_K	0.631	0.62
273_V	325_A	0.630	0.62
105_A	131_T	0.629	0.61
424_A	433_V	0.628	0.61
308_R	333_V	0.628	0.61
417_N	512_L	0.626	0.61
483_Q	488_V	0.626	0.61
271_T	329_A	0.626	0.61
191_W	201_G	0.626	0.61
171_D	190_Y	0.625	0.61
34_K	38_S	0.624	0.61
418_V	424_A	0.623	0.61
241_A	262_Y	0.621	0.60
327_A	331_I	0.621	0.60
354_A	357_T	0.621	0.60
25_D	118_Q	0.621	0.60
320_P	324_D	0.621	0.60
524_Q	535_N	0.620	0.60
42_E	208_E	0.620	0.60
405_V	411_R	0.619	0.60
38_S	55_T	0.617	0.60
165_V	205_V	0.615	0.60
329_A	333_V	0.615	0.60
473_F	480_V	0.614	0.60
500_R	529_D	0.611	0.59
506_G	556_L	0.610	0.59
9_D	12_D	0.610	0.59
529_D	558_V	0.607	0.59
481_F	486_P	0.607	0.59
261_L	391_V	0.606	0.59
340_A	349_E	0.606	0.59
8_D	11_G	0.605	0.58
14_R	103_D	0.604	0.58
340_A	353_V	0.604	0.58
314_G	324_D	0.604	0.58
319_A	325_A	0.603	0.58
286_R	289_L	0.603	0.58
284_D	303_F	0.602	0.58
272_V	318_A	0.600	0.58
343_V	351_A	0.600	0.58
370_G	392_G	0.599	0.58
38_S	288_L	0.599	0.58
110_D	142_T	0.599	0.58
244_V	306_V	0.599	0.58
22_G	27_G	0.598	0.58
470_P	541_I	0.597	0.57
321_D	339_V	0.597	0.57
285_V	304_G	0.597	0.57
421_L	427_N	0.596	0.57
340_A	350_L	0.596	0.57
256_T	302_R	0.595	0.57
51_H	258_D	0.595	0.57
488_V	540_S	0.594	0.57
528_V	540_S	0.594	0.57
81_L	299_T	0.593	0.57
366_A	375_L	0.592	0.57
289_L	296_E	0.590	0.57
193_V	201_G	0.589	0.56
280_P	515_A	0.589	0.56
510_N	555_E	0.589	0.56
24_V	88_H	0.589	0.56
20_V	288_L	0.588	0.56
375_L	414_L	0.588	0.56
55_T	481_F	0.586	0.56
120_E	127_K	0.585	0.56
196_F	200_V	0.585	0.56
292_G	296_E	0.584	0.56
231_E	234_V	0.584	0.56
200_V	219_V	0.584	0.56
400_A	427_N	0.583	0.56
125_I	401_M	0.583	0.56
284_D	289_L	0.583	0.56
432_S	450_A	0.581	0.55
149_N	167_S	0.580	0.55
480_V	550_I	0.580	0.55
484_N	488_V	0.580	0.55
38_S	253_F	0.579	0.55
92_S	96_S	0.579	0.55
273_V	328_G	0.579	0.55
34_K	114_G	0.578	0.55
490_G	496_G	0.577	0.55
58_P	529_D	0.577	0.55
543_G	550_I	0.575	0.55
281_I	303_F	0.574	0.55
20_V	38_S	0.573	0.54
247_V	369_L	0.572	0.54
341_D	351_A	0.572	0.54
83_I	372_L	0.572	0.54
483_Q	520_G	0.572	0.54
419_D	509_G	0.571	0.54
470_P	562_E	0.571	0.54
59_L	218_T	0.570	0.54
395_A	421_L	0.569	0.54
13_L	231_E	0.568	0.54
415_G	435_V	0.568	0.54
470_P	479_H	0.568	0.54
413_L	432_S	0.567	0.54
81_L	300_E	0.566	0.54
46_G	50_Q	0.566	0.54
422_P	426_E	0.565	0.53
292_G	298_R	0.565	0.53
511_D	551_K	0.564	0.53
52_I	417_N	0.564	0.53
385_P	541_I	0.563	0.53
253_F	302_R	0.563	0.53
426_E	432_S	0.563	0.53
302_R	452_V	0.562	0.53
44_E	48_I	0.562	0.53
8_D	235_T	0.561	0.53
245_L	430_R	0.561	0.53
84_D	87_G	0.560	0.53
443_Q	447_D	0.560	0.53
274_V	316_K	0.559	0.53
83_I	375_L	0.558	0.53
483_Q	548_R	0.558	0.53
323_D	327_A	0.557	0.52
26_H	116_Q	0.557	0.52
111_V	137_A	0.556	0.52
147_N	164_R	0.556	0.52
21_L	105_A	0.556	0.52
485_D	504_V	0.554	0.52
450_A	565_A	0.553	0.52
521_I	527_D	0.552	0.52
37_G	213_V	0.552	0.52
194_Q	198_K	0.551	0.52
508_E	554_D	0.550	0.51
109_V	115_F	0.550	0.51
331_I	334_V	0.549	0.51
44_E	442_Y	0.548	0.51
253_F	256_T	0.548	0.51
142_T	443_Q	0.548	0.51
171_D	192_R	0.548	0.51
413_L	435_V	0.546	0.51
53_G	122_A	0.546	0.51
361_G	410_H	0.546	0.51
531_A	535_N	0.544	0.51
492_E	533_A	0.544	0.51
414_L	424_A	0.544	0.51
119_T	135_V	0.543	0.51
419_D	512_L	0.543	0.51
253_F	304_G	0.543	0.51
271_T	322_L	0.543	0.51
107_L	120_E	0.542	0.50
285_V	488_V	0.541	0.50
424_A	510_N	0.541	0.50
122_A	129_T	0.541	0.50
124_R	390_E	0.541	0.50
420_V	498_L	0.541	0.50
13_L	58_P	0.540	0.50
421_L	464_F	0.539	0.50
127_K	471_A	0.539	0.50
297_M	300_E	0.539	0.50
322_L	325_A	0.537	0.50
470_P	557_W	0.537	0.50
519_K	550_I	0.536	0.50
293_D	298_R	0.535	0.50
480_V	483_Q	0.535	0.50
326_M	330_P	0.535	0.50
292_G	303_F	0.534	0.49
219_V	222_G	0.533	0.49
25_D	28_K	0.533	0.49
81_L	260_I	0.533	0.49
422_P	470_P	0.532	0.49
49_T	95_R	0.532	0.49
483_Q	522_Q	0.532	0.49
458_E	462_A	0.532	0.49
23_H	91_F	0.531	0.49
494_V	533_A	0.530	0.49
330_P	334_V	0.530	0.49
166_R	193_V	0.529	0.49
224_A	531_A	0.526	0.48
98_G	392_G	0.526	0.48
420_V	435_V	0.525	0.48
248_K	258_D	0.523	0.48
425_A	437_N	0.523	0.48
22_G	95_R	0.523	0.48
134_V	203_I	0.522	0.48
502_T	518_V	0.522	0.48
485_D	522_Q	0.521	0.48
390_E	427_N	0.521	0.48
87_G	264_G	0.521	0.48
17_I	211_E	0.521	0.48
56_A	287_A	0.520	0.48
511_D	549_D	0.519	0.47
34_K	211_E	0.519	0.47
328_G	507_I	0.519	0.47
467_I	518_V	0.519	0.47
435_V	522_Q	0.518	0.47
237_D	320_P	0.518	0.47
281_I	338_D	0.518	0.47
142_T	417_N	0.518	0.47
550_I	556_L	0.517	0.47
32_L	57_V	0.517	0.47
23_H	26_H	0.517	0.47
253_F	285_V	0.517	0.47
473_F	489_V	0.517	0.47
15_T	56_A	0.516	0.47
50_Q	95_R	0.516	0.47
241_A	317_V	0.516	0.47
273_V	332_R	0.515	0.47
494_V	553_G	0.514	0.47
89_H	332_R	0.514	0.47
425_A	470_P	0.513	0.47
234_V	297_M	0.513	0.47
342_V	349_E	0.511	0.46
116_Q	120_E	0.510	0.46
499_K	558_V	0.510	0.46
205_V	389_A	0.509	0.46
20_V	40_V	0.509	0.46
43_G	452_V	0.509	0.46
424_A	428_A	0.508	0.46
364_V	388_S	0.508	0.46
278_P	322_L	0.508	0.46
480_V	540_S	0.508	0.46
285_V	293_D	0.507	0.46
17_I	22_G	0.507	0.46
95_R	392_G	0.507	0.46
392_G	490_G	0.507	0.46
33_D	50_Q	0.507	0.46
424_A	431_E	0.506	0.46
105_A	129_T	0.506	0.46
89_H	210_G	0.506	0.46
387_M	483_Q	0.505	0.46
35_I	196_F	0.505	0.46
492_E	534_G	0.504	0.46
116_Q	564_H	0.504	0.46
130_G	226_R	0.503	0.45
137_A	148_P	0.503	0.45
506_G	512_L	0.503	0.45
114_G	164_R	0.503	0.45
365_K	388_S	0.503	0.45
274_V	315_L	0.502	0.45
294_L	298_R	0.502	0.45
21_L	126_L	0.501	0.45
96_S	128_D	0.501	0.45
420_V	511_D	0.501	0.45
333_V	499_K	0.501	0.45
425_A	495_S	0.500	0.45
205_V	540_S	0.500	0.45

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1g7sA	1	0.9283	100	0.312	Contact Map
4upyB	1	0.9517	100	0.363	Contact Map
3wbiA	1	0.9217	100	0.372	Contact Map
4n3nA	2	0.94	100	0.387	Contact Map
3izyP	1	0.8167	100	0.391	Contact Map
1zo1I	1	0.8183	100	0.397	Contact Map
3j4jA	1	0.8317	100	0.412	Contact Map
4n3sA	1	0.7067	100	0.533	Contact Map
4kjzA	1	0.675	100	0.541	Contact Map
1darA	1	0.78	100	0.602	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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