GREMLIN Database
Q9HNP8 - Oligopeptidase
UniProt: Q9HNP8 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 632 (545)
Sequences: 6827 (4722)
Seq/√Len: 202.3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
249_Q253_E6.9741.00
199_E272_T5.3631.00
287_D291_Q5.3241.00
602_Q607_D5.2461.00
193_L279_K4.8411.00
187_S190_V4.6831.00
595_A599_E3.9031.00
595_A603_D3.7601.00
288_T291_Q3.5971.00
572_D584_R3.4051.00
243_P341_M3.3001.00
246_A249_Q3.2661.00
518_R521_E3.1651.00
57_Y66_A2.9881.00
521_E525_D2.9781.00
312_D529_A2.8591.00
278_V282_E2.8561.00
584_R587_E2.7171.00
587_E603_D2.6141.00
525_D529_A2.5401.00
268_S272_T2.5361.00
291_Q301_V2.5051.00
64_E131_R2.5001.00
65_A69_D2.4811.00
172_E176_D2.4321.00
65_A68_E2.4261.00
169_A172_E2.3871.00
376_A433_Q2.2991.00
64_E68_E2.2301.00
246_A250_T2.2161.00
73_E104_D2.1921.00
524_G528_R2.1761.00
69_D73_E2.1481.00
361_I376_A2.1351.00
71_Q138_D2.1081.00
358_E362_E2.1061.00
595_A600_L2.1041.00
571_E575_D2.0961.00
92_L96_E2.0711.00
522_V525_D2.0661.00
193_L196_E2.0551.00
68_E72_A2.0511.00
58_E62_E2.0421.00
286_Y295_D2.0361.00
507_L518_R2.0331.00
572_D576_D2.0271.00
168_L172_E1.9911.00
243_P345_D1.9911.00
200_V273_Q1.9681.00
62_E65_A1.9601.00
190_V193_L1.8921.00
591_R600_L1.8751.00
71_Q75_D1.8731.00
192_G196_E1.8701.00
197_L276_R1.8701.00
222_E228_A1.8671.00
503_R525_D1.8611.00
477_R481_N1.8531.00
302_E306_T1.8421.00
576_D580_D1.8391.00
503_R507_L1.8391.00
408_I429_S1.8171.00
577_D580_D1.7991.00
117_D397_Y1.7941.00
156_E159_Q1.7901.00
352_E355_D1.7891.00
66_A69_D1.7861.00
61_D65_A1.7751.00
309_D313_D1.7751.00
503_R522_V1.7591.00
270_M504_L1.7571.00
599_E603_D1.7551.00
242_T247_F1.7401.00
123_Q127_A1.7341.00
188_A192_G1.7311.00
68_E71_Q1.7291.00
154_T157_Q1.7291.00
591_R595_A1.7281.00
305_D502_Q1.7081.00
467_L473_D1.7021.00
166_P170_A1.6691.00
352_E412_Y1.6681.00
52_A55_S1.6651.00
166_P169_A1.6601.00
220_T228_A1.6561.00
368_G371_Y1.6481.00
467_L472_D1.6451.00
181_M295_D1.6451.00
263_R520_D1.6431.00
184_H285_N1.6391.00
260_S263_R1.6381.00
314_N615_E1.6381.00
249_Q337_W1.6361.00
60_D131_R1.6051.00
466_L472_D1.5941.00
305_D309_D1.5901.00
580_D583_A1.5891.00
356_A361_I1.5881.00
66_A104_D1.5551.00
525_D528_R1.5541.00
294_L297_G1.5501.00
493_R497_F1.5481.00
398_S432_S1.5471.00
173_H177_D1.5401.00
87_D90_T1.5331.00
73_E76_A1.5251.00
503_R506_E1.5221.00
416_I463_V1.5131.00
357_R361_I1.5001.00
310_T314_N1.4901.00
240_L251_V1.4841.00
323_D350_D1.4811.00
236_F251_V1.4741.00
520_D544_W1.4731.00
197_L200_V1.4631.00
323_D326_R1.4631.00
300_P303_V1.4601.00
170_A173_H1.4591.00
59_T62_E1.4531.00
210_M266_I1.4491.00
158_L162_I1.4431.00
580_D584_R1.4421.00
103_R403_D1.4391.00
315_L491_L1.4361.00
326_R329_L1.4331.00
272_T275_K1.4271.00
306_T310_T1.4241.00
199_E202_G1.4171.00
576_D581_A1.4171.00
127_A131_R1.4121.00
222_E226_G1.4081.00
90_T93_A1.4061.00
245_R331_V1.4001.00
82_G149_E1.3991.00
55_S405_Q1.3981.00
211_L548_P1.3941.00
360_V423_A1.3891.00
60_D64_E1.3821.00
69_D104_D1.3741.00
571_E616_R1.3621.00
293_A297_G1.3591.00
325_K333_D1.3571.00
193_L283_A1.3571.00
370_D373_Q1.3511.00
223_D227_D1.3441.00
245_R335_E1.3411.00
358_E361_I1.3361.00
203_A269_T1.3301.00
196_E199_E1.3291.00
596_Y599_E1.3271.00
578_Q583_A1.3221.00
159_Q163_E1.3191.00
170_A176_D1.3181.00
147_D151_Q1.3181.00
67_F135_L1.3171.00
250_T254_Q1.3161.00
167_E172_E1.3101.00
72_A75_D1.3051.00
223_D226_G1.3011.00
369_E373_Q1.3011.00
599_E602_Q1.2961.00
362_E469_T1.2961.00
612_A616_R1.2951.00
578_Q581_A1.2931.00
50_K53_L1.2911.00
309_D529_A1.2871.00
245_R337_W1.2841.00
72_A76_A1.2831.00
453_V569_L1.2801.00
524_G541_E1.2781.00
193_L197_L1.2751.00
71_Q74_L1.2671.00
169_A173_H1.2651.00
571_E574_L1.2641.00
288_T506_E1.2631.00
280_L289_A1.2581.00
254_Q257_D1.2561.00
197_L280_L1.2331.00
180_R295_D1.2301.00
413_Q418_S1.2241.00
180_R185_T1.2241.00
362_E365_A1.2221.00
297_G558_Q1.2171.00
51_W54_A1.2161.00
469_T473_D1.2151.00
610_T613_P1.2081.00
586_R590_T1.2011.00
131_R135_L1.1941.00
496_L526_R1.1941.00
288_T301_V1.1861.00
467_L471_E1.1851.00
311_V495_T1.1811.00
270_M519_I1.1801.00
400_G403_D1.1791.00
368_G373_Q1.1771.00
583_A587_E1.1741.00
415_D418_S1.1731.00
271_K275_K1.1661.00
229_V251_V1.1641.00
146_F150_L1.1621.00
167_E170_A1.1601.00
155_R159_Q1.1591.00
64_E135_L1.1591.00
374_R377_D1.1571.00
355_D358_E1.1561.00
55_S58_E1.1481.00
231_I254_Q1.1461.00
116_S129_Q1.1441.00
99_D441_Y1.1431.00
497_F550_F1.1341.00
328_A349_P1.1321.00
538_D541_E1.1301.00
474_H477_R1.1151.00
305_D506_E1.1141.00
206_D210_M1.1111.00
77_L94_A1.1071.00
158_L161_M1.1061.00
253_E539_H1.1021.00
75_D142_A1.1001.00
499_D530_Y1.0941.00
587_E590_T1.0901.00
274_M504_L1.0881.00
186_R190_V1.0861.00
470_V473_D1.0761.00
321_H325_K1.0741.00
119_D122_D1.0731.00
365_A372_Q1.0711.00
180_R298_N1.0701.00
239_L251_V1.0621.00
138_D142_A1.0541.00
236_F255_F1.0541.00
75_D138_D1.0521.00
363_A377_D1.0511.00
476_R480_L1.0491.00
114_M399_G1.0481.00
398_S429_S1.0471.00
203_A207_A1.0471.00
466_L473_D1.0461.00
61_D64_E1.0451.00
528_R533_N1.0441.00
131_R134_S1.0401.00
236_F240_L1.0391.00
503_R526_R1.0371.00
66_A108_V1.0351.00
322_A325_K1.0331.00
157_Q160_S1.0321.00
233_Q237_T1.0321.00
502_Q506_E1.0291.00
368_G586_R1.0291.00
170_A174_Y1.0281.00
75_D82_G1.0261.00
192_G195_S1.0261.00
457_V569_L1.0251.00
507_L512_E1.0211.00
262_V265_T1.0211.00
310_T615_E1.0191.00
252_H256_Y1.0171.00
520_D524_G1.0171.00
361_I383_W1.0141.00
591_R603_D1.0141.00
326_R331_V1.0131.00
204_P273_Q1.0101.00
503_R529_A1.0091.00
313_D615_E1.0081.00
173_H176_D1.0061.00
346_S350_D1.0021.00
134_S138_D1.0011.00
466_L471_E0.9961.00
598_I602_Q0.9951.00
270_M544_W0.9941.00
313_D316_D0.9921.00
221_V224_P0.9901.00
494_Q497_F0.9891.00
76_A97_L0.9881.00
329_L342_P0.9881.00
129_Q133_A0.9881.00
279_K282_E0.9871.00
229_V235_N0.9871.00
460_A570_V0.9861.00
273_Q277_D0.9851.00
159_Q172_E0.9821.00
217_E220_T0.9801.00
303_V306_T0.9781.00
119_D391_G0.9761.00
313_D611_S0.9751.00
591_R594_S0.9731.00
470_V475_F0.9721.00
197_L279_K0.9690.99
365_A376_A0.9680.99
245_R338_D0.9660.99
96_E99_D0.9650.99
598_I608_M0.9640.99
194_L198_G0.9590.99
502_Q554_F0.9580.99
568_A606_V0.9580.99
62_E66_A0.9550.99
132_G135_L0.9510.99
150_L154_T0.9500.99
576_D584_R0.9490.99
223_D228_A0.9480.99
309_D499_D0.9480.99
270_M274_M0.9450.99
96_E100_A0.9430.99
70_V101_V0.9420.99
70_V139_V0.9420.99
253_E257_D0.9380.99
54_A58_E0.9370.99
466_L469_T0.9360.99
245_R249_Q0.9360.99
424_H452_E0.9360.99
247_F250_T0.9350.99
301_V305_D0.9350.99
92_L167_E0.9350.99
425_E428_H0.9330.99
184_H191_E0.9320.99
128_L131_R0.9310.99
378_G384_V0.9300.99
114_M401_T0.9280.99
89_E93_A0.9270.99
399_G407_F0.9250.99
600_L603_D0.9250.99
308_V499_D0.9250.99
294_L304_Y0.9240.99
466_L470_V0.9230.99
447_E597_P0.9230.99
94_A146_F0.9220.99
204_P207_A0.9220.99
257_D261_G0.9220.99
51_W56_I0.9100.99
202_G206_D0.9090.99
189_E192_G0.9070.99
504_L544_W0.9070.99
318_L492_Y0.9030.99
239_L242_T0.9020.99
115_R118_E0.9010.99
469_T472_D0.8980.99
598_I607_D0.8980.99
55_S407_F0.8980.99
585_Y589_L0.8950.99
71_Q142_A0.8940.99
490_T494_Q0.8930.99
206_D209_N0.8930.99
384_V426_L0.8920.99
83_R87_D0.8890.99
188_A191_E0.8890.99
408_I414_D0.8880.99
220_T225_A0.8860.99
159_Q162_I0.8850.99
244_D247_F0.8840.99
271_K519_I0.8830.99
526_R530_Y0.8810.99
504_L519_I0.8780.99
217_E221_V0.8770.99
54_A59_T0.8760.99
110_A399_G0.8760.99
447_E450_V0.8760.99
165_T168_L0.8740.99
198_G280_L0.8720.99
517_D521_E0.8720.99
405_Q436_S0.8710.99
457_V585_Y0.8700.99
89_E165_T0.8680.99
203_A272_T0.8670.99
572_D575_D0.8670.99
194_L280_L0.8660.99
81_E84_L0.8640.99
53_L56_I0.8620.99
147_D191_E0.8600.99
326_R332_D0.8590.99
165_T172_E0.8580.99
163_E167_E0.8580.99
221_V226_G0.8570.99
96_E167_E0.8540.99
233_Q255_F0.8540.99
129_Q205_S0.8530.99
174_Y177_D0.8490.99
375_V426_L0.8470.99
460_A566_A0.8470.99
277_D505_H0.8470.99
114_M397_Y0.8460.99
135_L138_D0.8460.99
350_D414_D0.8420.99
545_M551_Y0.8380.99
534_A537_D0.8380.99
424_H559_Y0.8380.99
302_E305_D0.8370.99
448_I451_A0.8340.98
496_L531_Y0.8340.98
113_S117_D0.8320.98
464_N574_L0.8310.98
157_Q161_M0.8310.98
396_A421_T0.8310.98
97_L100_A0.8300.98
105_A136_M0.8290.98
356_A363_A0.8260.98
63_W132_G0.8250.98
386_V410_M0.8210.98
276_R280_L0.8180.98
372_Q376_A0.8150.98
465_H469_T0.8140.98
150_L180_R0.8140.98
225_A250_T0.8130.98
389_N392_K0.8130.98
574_L577_D0.8130.98
59_T115_R0.8130.98
363_A423_A0.8100.98
147_D188_A0.8100.98
421_T549_H0.8090.98
143_T147_D0.8090.98
60_D128_L0.8080.98
121_R391_G0.8070.98
515_T518_R0.8050.98
70_V108_V0.8050.98
156_E160_S0.8040.98
170_A177_D0.8030.98
378_G426_L0.8030.98
611_S615_E0.8030.98
424_H428_H0.7970.98
84_L149_E0.7970.98
71_Q135_L0.7920.98
467_L470_V0.7910.98
63_W109_S0.7900.98
252_H336_M0.7860.98
139_V143_T0.7860.98
208_Y211_L0.7850.98
56_I404_T0.7840.98
436_S590_T0.7810.98
63_W67_F0.7800.98
371_Y375_V0.7800.98
549_H556_V0.7790.98
408_I413_Q0.7760.98
69_D72_A0.7750.98
66_A70_V0.7750.98
306_T309_D0.7730.98
67_F71_Q0.7710.97
93_A97_L0.7700.97
151_Q155_R0.7690.97
255_F258_T0.7680.97
56_I123_Q0.7680.97
273_Q553_N0.7680.97
405_Q438_H0.7670.97
359_H362_E0.7660.97
93_A96_E0.7650.97
109_S113_S0.7650.97
172_E175_F0.7630.97
357_R360_V0.7620.97
372_Q375_V0.7590.97
170_A442_V0.7550.97
67_F108_V0.7550.97
507_L522_V0.7540.97
494_Q560_A0.7520.97
267_G545_M0.7510.97
73_E100_A0.7490.97
472_D475_F0.7490.97
57_Y104_D0.7470.97
361_I372_Q0.7460.97
435_T593_S0.7460.97
414_D418_S0.7450.97
359_H419_M0.7430.97
170_A175_F0.7430.97
142_A146_F0.7420.97
304_Y308_V0.7420.97
464_N468_D0.7410.97
321_H334_L0.7410.97
277_D289_A0.7410.97
425_E452_E0.7390.97
114_M407_F0.7380.97
173_H596_Y0.7380.97
362_E465_H0.7370.97
549_H559_Y0.7350.97
229_V247_F0.7340.97
499_D503_R0.7340.97
319_Q323_D0.7330.97
356_A383_W0.7320.97
207_A210_M0.7310.97
417_S420_F0.7300.97
207_A211_L0.7270.96
565_A601_L0.7260.96
142_A145_F0.7260.96
523_Y543_E0.7250.96
268_S271_K0.7250.96
463_V479_I0.7250.96
171_Y175_F0.7250.96
146_F149_E0.7250.96
165_T170_A0.7240.96
491_L560_A0.7230.96
52_A355_D0.7220.96
137_T141_S0.7220.96
312_D499_D0.7220.96
479_I482_E0.7220.96
454_A589_L0.7210.96
70_V74_L0.7180.96
62_E74_L0.7180.96
267_G516_P0.7170.96
373_Q376_A0.7160.96
235_N388_E0.7150.96
275_K279_K0.7140.96
166_P172_E0.7130.96
133_A137_T0.7120.96
279_K283_A0.7110.96
200_V204_P0.7110.96
113_S399_G0.7100.96
92_L165_T0.7090.96
319_Q322_A0.7090.96
396_A408_I0.7080.96
428_H452_E0.7080.96
547_I550_F0.7060.96
587_E591_R0.7060.96
58_E61_D0.7040.96
65_A74_L0.7020.96
349_P475_F0.7020.96
374_R430_L0.7010.96
56_I60_D0.7010.96
148_P151_Q0.7010.96
214_A259_I0.7000.96
583_A586_R0.7000.96
200_V203_A0.6990.96
353_Y386_V0.6990.96
565_A608_M0.6990.96
520_D541_E0.6970.95
60_D63_W0.6950.95
155_R158_L0.6940.95
457_V570_V0.6930.95
220_T223_D0.6910.95
370_D586_R0.6890.95
134_S137_T0.6880.95
122_D127_A0.6880.95
307_L560_A0.6860.95
124_E128_L0.6850.95
450_V600_L0.6830.95
496_L527_K0.6820.95
301_V506_E0.6820.95
168_L176_D0.6810.95
276_R279_K0.6800.95
60_D74_L0.6800.95
451_A454_A0.6800.95
257_D260_S0.6780.95
331_V334_L0.6780.95
82_G148_P0.6780.95
172_E177_D0.6770.95
356_A412_Y0.6760.95
271_K516_P0.6740.95
349_P352_E0.6740.95
118_E409_L0.6730.95
374_R433_Q0.6720.94
420_F462_L0.6710.94
70_V73_E0.6710.94
349_P355_D0.6700.94
378_G383_W0.6690.94
210_M269_T0.6680.94
181_M296_S0.6640.94
457_V573_I0.6630.94
452_E559_Y0.6630.94
208_Y212_T0.6630.94
351_I412_Y0.6620.94
310_T313_D0.6620.94
222_E225_A0.6610.94
528_R534_A0.6590.94
435_T444_S0.6590.94
171_Y174_Y0.6590.94
291_Q295_D0.6580.94
467_L476_R0.6560.94
401_T407_F0.6560.94
177_D298_N0.6560.94
121_R390_R0.6530.94
239_L247_F0.6520.94
167_E176_D0.6520.94
166_P176_D0.6520.94
115_R119_D0.6510.94
249_Q335_E0.6500.93
304_Y502_Q0.6500.93
521_E524_G0.6460.93
184_H187_S0.6460.93
207_A268_S0.6450.93
224_P247_F0.6450.93
142_A195_S0.6440.93
260_S542_R0.6430.93
127_A130_A0.6430.93
289_A293_A0.6420.93
83_R90_T0.6410.93
425_E459_E0.6410.93
367_L374_R0.6380.93
364_V372_Q0.6360.93
500_V523_Y0.6360.93
385_D389_N0.6330.93
95_L153_C0.6330.93
107_T403_D0.6330.93
495_T560_A0.6290.92
248_R338_D0.6290.92
416_I420_F0.6290.92
463_V483_Y0.6290.92
442_V593_S0.6280.92
56_I59_T0.6280.92
209_N213_D0.6270.92
360_V414_D0.6270.92
231_I239_L0.6260.92
323_D534_A0.6260.92
258_T262_V0.6260.92
290_R502_Q0.6250.92
547_I556_V0.6250.92
62_E71_Q0.6230.92
154_T185_T0.6220.92
117_D393_R0.6210.92
439_Q442_V0.6210.92
94_A97_L0.6210.92
50_K389_N0.6210.92
408_I412_Y0.6200.92
258_T261_G0.6190.92
169_A176_D0.6180.92
453_V601_L0.6180.92
100_A103_R0.6180.92
468_D473_D0.6180.92
341_M345_D0.6170.92
181_M292_A0.6160.92
73_E97_L0.6160.92
133_A136_M0.6150.91
290_R305_D0.6130.91
126_Q129_Q0.6130.91
240_L255_F0.6110.91
368_G375_V0.6100.91
212_T266_I0.6080.91
229_V239_L0.6070.91
485_E488_R0.6070.91
334_L339_L0.6060.91
543_E546_R0.6050.91
84_L87_D0.6050.91
396_A451_A0.6040.91
335_E537_D0.6040.91
165_T169_A0.6040.91
548_P552_Y0.6030.91
254_Q258_T0.6030.91
334_L342_P0.6020.91
460_A567_V0.6020.91
370_D590_T0.6010.91
447_E596_Y0.6010.91
331_V335_E0.6000.90
183_P186_R0.5990.90
140_S144_S0.5960.90
602_Q609_S0.5960.90
77_L101_V0.5960.90
410_M421_T0.5950.90
117_D409_L0.5950.90
290_R301_V0.5940.90
429_S432_S0.5930.90
196_E283_A0.5930.90
217_E222_E0.5920.90
156_E162_I0.5910.90
343_I486_R0.5910.90
329_L332_D0.5900.90
232_S235_N0.5890.90
355_D359_H0.5890.90
299_I304_Y0.5890.90
134_S141_S0.5880.90
216_L232_S0.5870.89
116_S126_Q0.5870.89
90_T97_L0.5870.89
310_T610_T0.5850.89
363_A368_G0.5840.89
424_H549_H0.5830.89
291_Q302_E0.5830.89
60_D65_A0.5830.89
345_D474_H0.5820.89
373_Q377_D0.5810.89
425_E559_Y0.5800.89
139_V142_A0.5800.89
298_N596_Y0.5790.89
468_D472_D0.5780.89
361_I366_P0.5780.89
74_L139_V0.5760.89
60_D71_Q0.5760.89
446_Y451_A0.5750.89
520_D542_R0.5740.88
400_G432_S0.5740.88
572_D581_A0.5740.88
207_A212_T0.5720.88
194_L197_L0.5720.88
208_Y548_P0.5720.88
73_E102_Y0.5720.88
393_R397_Y0.5700.88
84_L94_A0.5700.88
440_P443_Y0.5700.88
108_V132_G0.5700.88
207_A213_D0.5680.88
100_A104_D0.5680.88
87_D161_M0.5680.88
434_Y590_T0.5680.88
351_I482_E0.5670.88
139_V145_F0.5670.88
210_M264_N0.5660.88
103_R107_T0.5650.88
500_V504_L0.5650.88
588_F600_L0.5650.88
571_E615_E0.5650.88
124_E127_A0.5640.88
211_L266_I0.5640.88
431_H446_Y0.5640.88
237_T340_Y0.5630.87
495_T499_D0.5630.87
438_H590_T0.5620.87
197_L201_F0.5620.87
282_E287_D0.5610.87
126_Q209_N0.5610.87
77_L143_T0.5600.87
475_F479_I0.5590.87
252_H335_E0.5590.87
587_E595_A0.5570.87
384_V429_S0.5570.87
210_M213_D0.5560.87
88_G92_L0.5550.87
106_K400_G0.5550.87
55_S59_T0.5550.87
104_D403_D0.5520.86
274_M519_I0.5510.86
362_E366_P0.5510.86
252_H337_W0.5510.86
524_G539_H0.5510.86
64_E67_F0.5510.86
310_T611_S0.5500.86
166_P174_Y0.5500.86
385_D392_K0.5500.86
370_D374_R0.5500.86
353_Y479_I0.5490.86
54_A61_D0.5490.86
65_A71_Q0.5470.86
58_E65_A0.5470.86
500_V544_W0.5470.86
118_E389_N0.5470.86
479_I483_Y0.5470.86
601_L608_M0.5450.86
61_D74_L0.5450.86
160_S163_E0.5440.86
266_I545_M0.5430.86
245_R332_D0.5430.86
364_V367_L0.5420.85
292_A296_S0.5420.85
578_Q582_A0.5420.85
499_D529_A0.5420.85
207_A269_T0.5410.85
581_A604_A0.5410.85
455_S549_H0.5400.85
326_R335_E0.5380.85
212_T233_Q0.5380.85
177_D180_R0.5370.85
221_V225_A0.5360.85
243_P348_G0.5360.85
102_Y139_V0.5360.85
110_A445_N0.5350.85
357_R386_V0.5350.85
136_M140_S0.5350.85
481_N485_E0.5350.85
103_R106_K0.5340.85
66_A77_L0.5330.85
97_L101_V0.5330.85
273_Q551_Y0.5330.85
83_R93_A0.5330.85
527_K540_I0.5320.84
260_S267_G0.5320.84
432_S435_T0.5310.84
428_H559_Y0.5300.84
110_A113_S0.5290.84
126_Q130_A0.5290.84
352_E478_H0.5290.84
244_D250_T0.5280.84
339_L489_S0.5270.84
98_R102_Y0.5260.84
120_T393_R0.5260.84
420_F463_V0.5260.84
474_H478_H0.5260.84
523_Y527_K0.5260.84
77_L97_L0.5260.84
128_L132_G0.5250.84
130_A133_A0.5250.84
280_L292_A0.5240.84
360_V426_L0.5230.83
305_D499_D0.5230.83
91_L168_L0.5210.83
238_N241_K0.5210.83
336_M538_D0.5210.83
437_E440_P0.5200.83
388_E411_N0.5200.83
410_M413_Q0.5200.83
130_A209_N0.5190.83
563_I566_A0.5190.83
346_S485_E0.5190.83
89_E152_A0.5160.83
300_P609_S0.5150.82
224_P228_A0.5150.82
496_L543_E0.5130.82
308_V495_T0.5130.82
573_I577_D0.5130.82
315_L492_Y0.5130.82
251_V255_F0.5120.82
54_A62_E0.5120.82
384_V410_M0.5120.82
252_H539_H0.5110.82
428_H459_E0.5110.82
66_A107_T0.5110.82
216_L391_G0.5100.82
171_Y176_D0.5080.82
455_S459_E0.5070.81
395_G421_T0.5070.81
374_R378_G0.5060.81
452_E459_E0.5050.81
424_H459_E0.5050.81
453_V565_A0.5050.81
145_F149_E0.5030.81
354_A357_R0.5020.81
56_I74_L0.5020.81
386_V422_L0.5020.81
186_R191_E0.5020.81
366_P369_E0.5020.81
117_D399_G0.5020.81
378_G429_S0.5010.81
74_L77_L0.5010.81
448_I558_Q0.5010.81
326_R333_D0.5010.81
492_Y495_T0.5000.81
416_I479_I0.5000.81
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3ce2A 1 0.9304 100 0.207 Contact Map
2qr4A 2 0.818 100 0.248 Contact Map
4ka7A 1 0.9003 100 0.333 Contact Map
1y791 1 0.9051 100 0.335 Contact Map
2o3eA 1 0.8829 100 0.346 Contact Map
2o36A 1 0.8655 100 0.354 Contact Map
3sksA 1 0.8449 100 0.363 Contact Map
3ahnA 1 0.8703 100 0.37 Contact Map
1r42A 1 0.807 100 0.486 Contact Map
4ca6A 1 0.8212 100 0.491 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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