GREMLIN Database
Q9HNN3 - General stress protein 69
UniProt: Q9HNN3 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 352 (300)
Sequences: 24725 (15623)
Seq/√Len: 902.0

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
42_Y293_E3.6131.00
33_E68_E3.3241.00
71_A119_G3.0901.00
261_G308_E2.9981.00
112_E152_R2.9971.00
42_Y46_H2.6371.00
108_R150_D2.5871.00
305_S308_E2.5731.00
5_E12_E2.5641.00
111_V147_L2.5601.00
260_D311_R2.5551.00
145_D149_A2.4541.00
108_R146_D2.4071.00
122_H154_D2.2411.00
255_R259_R2.2091.00
61_R64_E2.2091.00
4_R15_E2.1301.00
17_G50_Y2.0461.00
46_H293_E2.0431.00
104_V146_D2.0431.00
306_D310_E2.0401.00
275_S309_R2.0151.00
73_H76_E1.9821.00
127_Q180_S1.9661.00
37_L72_E1.9331.00
32_D35_D1.9231.00
81_T123_V1.9081.00
253_A256_F1.8911.00
260_D308_E1.8661.00
146_D149_A1.8501.00
199_S203_R1.8301.00
256_F311_R1.8201.00
83_V107_L1.8041.00
42_Y289_K1.7941.00
297_S300_E1.7781.00
263_R301_T1.7761.00
46_H296_A1.7761.00
146_D150_D1.7741.00
310_E314_E1.7591.00
127_Q210_I1.7411.00
104_V108_R1.7381.00
20_A51_F1.7321.00
83_V126_L1.7161.00
43_A48_I1.7151.00
37_L68_E1.7091.00
143_L146_D1.7081.00
289_K293_E1.7071.00
111_V126_L1.7061.00
37_L69_A1.6881.00
195_H198_D1.6841.00
109_D113_K1.6751.00
80_A127_Q1.6711.00
33_E37_L1.6591.00
168_A172_H1.6551.00
264_T294_A1.6341.00
64_E117_R1.6191.00
3_H12_E1.5891.00
271_Q301_T1.5831.00
35_D38_E1.5811.00
37_L41_E1.5771.00
145_D176_A1.5721.00
40_V69_A1.5631.00
108_R112_E1.5451.00
263_R267_Q1.5241.00
111_V123_V1.5141.00
79_V120_V1.5061.00
163_S166_W1.5031.00
200_V209_L1.4921.00
55_D110_A1.4791.00
81_T114_S1.4691.00
113_K117_R1.4611.00
201_R277_D1.4581.00
153_A156_I1.4491.00
44_L77_M1.4281.00
11_V78_T1.4171.00
42_Y45_D1.3881.00
311_R314_E1.3861.00
256_F260_D1.3811.00
131_P166_W1.3741.00
113_K116_D1.3721.00
168_A199_S1.3681.00
68_E119_G1.3571.00
168_A202_E1.3501.00
253_A311_R1.3501.00
51_F66_L1.3421.00
67_G119_G1.3381.00
11_V155_A1.3321.00
263_R268_A1.3311.00
108_R143_L1.3291.00
264_T267_Q1.3271.00
276_F313_A1.3191.00
171_D203_R1.3151.00
49_T78_T1.3121.00
41_E72_E1.3081.00
128_L144_L1.3041.00
184_V189_E1.2991.00
147_L153_A1.2981.00
201_R278_E1.2971.00
255_R265_M1.2931.00
123_V153_A1.2811.00
164_I199_S1.2771.00
104_V142_D1.2661.00
5_E10_G1.2631.00
293_E297_S1.2571.00
74_G120_V1.2461.00
39_M292_I1.2451.00
64_E68_E1.2411.00
208_S281_T1.2311.00
38_E289_K1.2231.00
192_V209_L1.2181.00
41_E45_D1.2161.00
271_Q275_S1.2051.00
50_Y80_A1.2011.00
187_V312_V1.2001.00
155_A179_D1.1991.00
290_A293_E1.1991.00
252_D255_R1.1871.00
125_V180_S1.1771.00
171_D199_S1.1751.00
15_E274_L1.1741.00
63_E114_S1.1721.00
183_Y209_L1.1671.00
34_D38_E1.1671.00
112_E116_D1.1671.00
38_E42_Y1.1661.00
78_T125_V1.1651.00
267_Q297_S1.1611.00
144_L156_I1.1561.00
142_D146_D1.1501.00
20_A66_L1.1481.00
257_L268_A1.1461.00
55_D106_Y1.1421.00
286_F292_I1.1411.00
86_D101_E1.1261.00
252_D256_F1.1201.00
112_E150_D1.1151.00
156_I178_F1.1101.00
15_E299_S1.1101.00
40_V51_F1.1101.00
273_L282_V1.1021.00
198_D202_E1.0921.00
70_L77_M1.0901.00
158_V178_F1.0871.00
187_V269_A1.0841.00
41_E69_A1.0841.00
256_F259_R1.0801.00
267_Q294_A1.0791.00
118_L123_V1.0781.00
105_D109_D1.0571.00
225_T255_R1.0551.00
64_E116_D1.0541.00
14_S48_I1.0491.00
147_L152_R1.0371.00
254_L265_M1.0371.00
104_V139_D1.0291.00
102_M128_L1.0241.00
74_G122_H1.0191.00
106_Y109_D1.0181.00
50_Y210_I1.0151.00
138_P173_A1.0151.00
169_E172_H1.0141.00
167_L205_A1.0091.00
145_D148_R1.0061.00
286_F291_D1.0041.00
245_E249_E0.9961.00
9_S179_D0.9891.00
307_A310_E0.9861.00
14_S49_T0.9811.00
138_P169_E0.9801.00
108_R111_V0.9801.00
44_L73_H0.9801.00
292_I296_A0.9751.00
201_R279_V0.9741.00
276_F309_R0.9731.00
168_A203_R0.9731.00
185_G276_F0.9731.00
108_R147_L0.9711.00
46_H297_S0.9711.00
124_D154_D0.9701.00
104_V143_L0.9691.00
148_R179_D0.9621.00
230_L234_D0.9531.00
143_L147_L0.9531.00
190_Q193_H0.9511.00
310_E313_A0.9411.00
180_S210_I0.9361.00
208_S280_A0.9311.00
233_G237_G0.9301.00
274_L298_A0.9291.00
158_V167_L0.9211.00
142_D145_D0.9191.00
197_V209_L0.9151.00
20_A62_S0.9111.00
294_A297_S0.9051.00
139_D142_D0.9011.00
160_L212_R0.8951.00
110_A113_K0.8941.00
249_E252_D0.8901.00
147_L150_D0.8901.00
18_F43_A0.8881.00
225_T252_D0.8831.00
253_A315_L0.8831.00
211_P282_V0.8821.00
290_A294_A0.8801.00
148_R176_A0.8791.00
107_L147_L0.8761.00
48_I296_A0.8681.00
140_V143_L0.8671.00
234_D237_G0.8661.00
35_D289_K0.8661.00
33_E61_R0.8651.00
41_E73_H0.8641.00
40_V66_L0.8621.00
33_E65_L0.8591.00
3_H49_T0.8581.00
164_I168_A0.8531.00
257_L261_G0.8521.00
17_G284_P0.8441.00
141_L170_G0.8421.00
17_G281_T0.8401.00
80_A125_V0.8381.00
130_N160_L0.8381.00
307_A311_R0.8371.00
103_G106_Y0.8351.00
275_S306_D0.8351.00
38_E41_E0.8351.00
197_V201_R0.8341.00
248_W252_D0.8321.00
214_P284_P0.8311.00
137_T173_A0.8191.00
9_S155_A0.8161.00
304_L309_R0.8111.00
53_T66_L0.8111.00
194_N198_D0.8111.00
169_E173_A0.8101.00
109_D112_E0.8091.00
190_Q313_A0.8081.00
44_L76_E0.8051.00
16_V274_L0.8051.00
8_D204_G0.8031.00
226_P252_D0.8001.00
232_E237_G0.7971.00
40_V44_L0.7951.00
249_E253_A0.7901.00
288_S291_D0.7891.00
199_S202_E0.7891.00
141_L174_I0.7881.00
34_D37_L0.7851.00
287_R291_D0.7821.00
36_A65_L0.7801.00
275_S303_A0.7781.00
158_V161_G0.7771.00
141_L156_I0.7761.00
75_D122_H0.7761.00
39_M289_K0.7751.00
266_G294_A0.7721.00
115_M152_R0.7701.00
55_D117_R0.7681.00
73_H77_M0.7671.00
232_E236_R0.7641.00
198_D201_R0.7631.00
23_V39_M0.7541.00
235_H239_R0.7501.00
257_L315_L0.7481.00
137_T140_V0.7451.00
242_E245_E0.7441.00
219_L251_V0.7411.00
257_L308_E0.7401.00
141_L178_F0.7381.00
181_V200_V0.7331.00
18_F23_V0.7321.00
23_V36_A0.7321.00
61_R65_L0.7311.00
166_W169_E0.7291.00
144_L148_R0.7221.00
261_G305_S0.7181.00
83_V102_M0.7151.00
210_I281_T0.7151.00
192_V197_V0.7141.00
200_V205_A0.7101.00
171_D205_A0.7091.00
101_E106_Y0.7081.00
259_R262_E0.7071.00
268_A301_T0.7061.00
188_L219_L0.7041.00
55_D113_K0.7021.00
187_V316_Y0.7001.00
251_V255_R0.6981.00
63_E117_R0.6971.00
185_G273_L0.6961.00
185_G193_H0.6951.00
44_L51_F0.6941.00
158_V181_V0.6901.00
274_L282_V0.6871.00
164_I195_H0.6851.00
127_Q157_G0.6841.00
13_V50_Y0.6831.00
148_R153_A0.6831.00
257_L311_R0.6821.00
268_A312_V0.6821.00
165_G168_A0.6801.00
107_L140_V0.6801.00
44_L49_T0.6791.00
230_L236_R0.6791.00
211_P214_P0.6761.00
171_D177_A0.6751.00
226_P245_E0.6741.00
17_G283_T0.6741.00
149_A176_A0.6711.00
258_E268_A0.6691.00
263_R297_S0.6691.00
248_W251_V0.6681.00
68_E72_E0.6671.00
211_P279_V0.6641.00
80_A210_I0.6641.00
304_L308_E0.6601.00
6_L208_S0.6581.00
70_L73_H0.6581.00
149_A175_E0.6561.00
132_D135_E0.6561.00
260_D305_S0.6551.00
254_L269_A0.6551.00
270_I298_A0.6511.00
102_M140_V0.6481.00
43_A51_F0.6481.00
214_P273_L0.6471.00
3_H14_S0.6461.00
196_F200_V0.6461.00
53_T62_S0.6451.00
172_H203_R0.6451.00
131_P161_G0.6441.00
271_Q298_A0.6431.00
268_A304_L0.6431.00
233_G236_R0.6411.00
18_F39_M0.6361.00
171_D174_I0.6351.00
133_V166_W0.6331.00
261_G268_A0.6321.00
185_G190_Q0.6321.00
111_V143_L0.6281.00
145_D174_I0.6271.00
263_R271_Q0.6271.00
128_L140_V0.6241.00
52_D182_Q0.6231.00
272_W313_A0.6221.00
108_R152_R0.6201.00
24_G62_S0.6201.00
148_R156_I0.6181.00
291_D294_A0.6171.00
31_R36_A0.6171.00
145_D156_I0.6161.00
126_L153_A0.6151.00
81_T126_L0.6151.00
60_G117_R0.6111.00
157_G180_S0.6101.00
308_E311_R0.6091.00
267_Q301_T0.6071.00
268_A308_E0.6061.00
271_Q303_A0.6051.00
123_V126_L0.6001.00
254_L312_V0.6001.00
115_M120_V0.6001.00
246_T249_E0.5991.00
261_G301_T0.5971.00
269_A273_L0.5971.00
270_I295_W0.5961.00
164_I196_F0.5951.00
244_Y247_G0.5921.00
51_F70_L0.5911.00
21_W213_V0.5901.00
148_R177_A0.5881.00
83_V110_A0.5881.00
169_E202_E0.5871.00
168_A171_D0.5861.00
37_L65_L0.5861.00
214_P270_I0.5831.00
174_I178_F0.5811.00
313_A317_A0.5791.00
50_Y78_T0.5771.00
136_L169_E0.5771.00
63_E81_T0.5761.00
49_T76_E0.5761.00
14_S50_Y0.5751.00
39_M286_F0.5741.00
111_V115_M0.5731.00
114_S126_L0.5731.00
245_E248_W0.5721.00
85_Y130_N0.5721.00
68_E71_A0.5711.00
56_V85_Y0.5711.00
158_V170_G0.5701.00
185_G197_V0.5681.00
125_V157_G0.5681.00
44_L69_A0.5641.00
13_V281_T0.5641.00
64_E119_G0.5631.00
69_A72_E0.5621.00
219_L247_G0.5611.00
106_Y110_A0.5591.00
145_D175_E0.5591.00
31_R35_D0.5581.00
161_G167_L0.5581.00
183_Y196_F0.5571.00
86_D100_K0.5571.00
111_V152_R0.5551.00
190_Q316_Y0.5521.00
191_D194_N0.5521.00
289_K292_I0.5501.00
270_I284_P0.5501.00
17_G210_I0.5461.00
82_K129_H0.5451.00
70_L79_V0.5451.00
96_G99_P0.5451.00
138_P142_D0.5441.00
286_F295_W0.5431.00
232_E235_H0.5431.00
46_H292_I0.5421.00
300_E303_A0.5421.00
213_V217_S0.5411.00
16_V284_P0.5411.00
167_L200_V0.5391.00
7_G208_S0.5351.00
167_L181_V0.5351.00
238_F241_E0.5341.00
40_V70_L0.5331.00
35_D290_A0.5271.00
244_Y248_W0.5261.00
86_D99_P0.5241.00
107_L143_L0.5231.00
165_G169_E0.5211.00
188_L251_V0.5201.00
211_P273_L0.5141.00
55_D87_F0.5141.00
95_H98_L0.5141.00
258_E261_G0.5121.00
13_V78_T0.5111.00
297_S301_T0.5091.00
226_P248_W0.5091.00
226_P249_E0.5081.00
192_V196_F0.5071.00
8_D179_D0.5071.00
161_G181_V0.5051.00
57_Y82_K0.5031.00
112_E147_L0.5031.00
148_R155_A0.5031.00
16_V298_A0.5021.00
57_Y129_H0.5011.00
115_M121_D0.5001.00
148_R174_I0.5001.00
247_G250_K0.5001.00
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1pyfA 1 0.8693 100 0.185 Contact Map
1pz1A 1 0.929 100 0.189 Contact Map
4xk2A 5 0.8807 100 0.193 Contact Map
3n2tA 1 0.9148 100 0.193 Contact Map
3v0sA 1 0.7926 100 0.194 Contact Map
3erpA 6 0.8239 100 0.214 Contact Map
3lutA 3 0.8636 100 0.216 Contact Map
1lqaA 2 0.8892 100 0.218 Contact Map
3n6qA 5 0.8324 100 0.222 Contact Map
3eauA 3 0.8693 100 0.222 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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