Q9HNM2 - HALSA - GREMLIN Contacts

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Q9HNM2 - Uncharacterized protein

UniProt:	Q9HNM2	Sequences: MAAPGPSADTDTGLDALVDDAGFFRSLVEHGSDAIVTIDDDSTIRYANQGVHRVLGYRPDDLIGDSLTTIMPPRFHDAHFDAVDHYLETGDRRLDWNAIEMPGQHADGHEIQLSITFEEHVHNGVRAFSGIMRDVSRQKAYAATLESLQDITHTLMQARTPGAIGDHVVGAAVDIIGFPVASLYRCDDATGVLRPVAQSDAAAALFADPPALSAGSLAWHAFETNDSAVYHADADATTPVHDPDGPMIAEYAAPLGEHGVLLVGDTDDVAFDDHTSRLIELLAANTQAALERATREAERERQNEQLERFASIVSHDLRDPLQTARATVALAKAGDDDALTDLTAALDRMDALIADVLTLAKHGQTVGETEPVPVASVAADAWSTAGAPTASLSTAPDLPTLNADPERLRTLFENLFGNAVAHGGDDVTVTVGALTGADSGGFFVADDGDGFGDTDTAQLFDYGYTTDTDGTGFGLSIVRDIATAHGWTIDATTSDSGGARFTIHTQ	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	506 (471)
Sequences:	6303 (5324)
Seq/√Len:	245.3

ECOLI - ARCB RCSD EVGS RCSC ATOS KDPD TORS BARA DPIB DCUS
BACSU - KINE KINA YYCG PHOR KINC RESE CITS
HALSA - Q9HNM2 Q9HQG5 Q9HRG1 BAT O51970 Q9HQ16 Q9HRE4 Q9HR10 Q9HQB9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
328_V	342_L	4.467	1.00
478_V	489_I	4.210	1.00
494_S	497_G	4.109	1.00
292_R	296_E	3.984	1.00
479_R	483_T	3.981	1.00
33_D	133_R	3.697	1.00
490_D	502_T	3.353	1.00
445_A	500_R	3.090	1.00
411_L	482_A	3.061	1.00
148_L	152_T	2.866	1.00
452_G	455_D	2.710	1.00
292_R	295_R	2.561	1.00
456_T	491_A	2.540	1.00
391_S	428_T	2.465	1.00
442_F	503_I	2.459	1.00
160_T	163_A	2.432	1.00
34_A	54_V	2.401	1.00
423_G	447_D	2.400	1.00
332_K	340_T	2.389	1.00
415_L	444_V	2.348	1.00
293_A	296_E	2.342	1.00
432_G	443_F	2.331	1.00
446_D	450_G	2.325	1.00
191_G	195_P	2.310	1.00
430_T	445_A	2.304	1.00
139_K	142_A	2.288	1.00
482_A	503_I	2.286	1.00
36_V	130_G	2.277	1.00
491_A	501_F	2.276	1.00
401_L	404_D	2.257	1.00
433_A	442_F	2.248	1.00
434_L	441_G	2.248	1.00
443_F	500_R	2.247	1.00
168_V	286_T	2.241	1.00
411_L	481_I	2.215	1.00
403_A	408_L	2.195	1.00
441_G	504_H	2.176	1.00
439_S	504_H	2.103	1.00
453_D	456_T	2.091	1.00
217_L	221_A	2.066	1.00
481_I	485_H	2.029	1.00
441_G	502_T	2.021	1.00
492_T	500_R	2.010	1.00
422_H	465_T	1.995	1.00
50_G	53_R	1.959	1.00
357_L	360_A	1.948	1.00
451_F	459_L	1.923	1.00
371_P	402_N	1.916	1.00
400_T	404_D	1.907	1.00
166_D	170_G	1.903	1.00
403_A	485_H	1.883	1.00
456_T	493_T	1.883	1.00
57_Y	106_A	1.877	1.00
373_P	376_S	1.877	1.00
142_A	146_E	1.852	1.00
325_R	346_L	1.846	1.00
407_R	410_T	1.826	1.00
72_P	75_F	1.822	1.00
372_V	403_A	1.821	1.00
434_L	443_F	1.807	1.00
443_F	502_T	1.784	1.00
220_H	224_T	1.784	1.00
31_G	35_I	1.768	1.00
326_A	330_L	1.757	1.00
28_V	46_Y	1.753	1.00
169_V	181_A	1.744	1.00
301_R	304_E	1.742	1.00
428_T	447_D	1.725	1.00
389_T	392_L	1.695	1.00
36_V	51_V	1.684	1.00
393_S	430_T	1.676	1.00
404_D	410_T	1.674	1.00
432_G	445_A	1.664	1.00
412_F	442_F	1.654	1.00
58_R	61_D	1.651	1.00
350_D	354_A	1.650	1.00
255_L	287_Q	1.641	1.00
85_H	89_T	1.640	1.00
370_E	405_P	1.639	1.00
376_S	380_D	1.632	1.00
271_F	275_T	1.630	1.00
328_V	332_K	1.628	1.00
75_F	102_P	1.608	1.00
451_F	455_D	1.598	1.00
332_K	343_T	1.597	1.00
338_A	345_A	1.568	1.00
66_S	69_T	1.562	1.00
84_D	88_E	1.544	1.00
455_D	458_Q	1.544	1.00
451_F	456_T	1.533	1.00
65_D	69_T	1.533	1.00
337_D	341_D	1.510	1.00
36_V	44_I	1.506	1.00
79_H	82_A	1.504	1.00
303_N	306_L	1.500	1.00
404_D	407_R	1.500	1.00
80_F	84_D	1.489	1.00
411_L	478_V	1.485	1.00
461_D	464_Y	1.484	1.00
233_D	236_A	1.476	1.00
216_S	219_W	1.468	1.00
220_H	228_A	1.464	1.00
340_T	344_A	1.459	1.00
339_L	345_A	1.457	1.00
482_A	487_W	1.453	1.00
324_A	346_L	1.452	1.00
61_D	106_A	1.448	1.00
346_L	349_M	1.441	1.00
353_I	356_V	1.439	1.00
105_H	109_H	1.435	1.00
452_G	495_D	1.431	1.00
341_D	345_A	1.424	1.00
349_M	352_L	1.422	1.00
347_D	351_A	1.419	1.00
327_T	330_L	1.401	1.00
348_R	352_L	1.397	1.00
349_M	357_L	1.396	1.00
377_V	381_A	1.378	1.00
357_L	361_K	1.371	1.00
493_T	499_A	1.366	1.00
490_D	503_I	1.363	1.00
89_T	92_R	1.348	1.00
316_D	320_P	1.331	1.00
83_V	86_Y	1.330	1.00
336_D	339_L	1.327	1.00
311_S	316_D	1.324	1.00
299_R	303_N	1.320	1.00
393_S	428_T	1.319	1.00
328_V	331_A	1.318	1.00
314_S	319_D	1.317	1.00
349_M	353_I	1.317	1.00
303_N	307_E	1.316	1.00
470_G	473_F	1.304	1.00
138_Q	142_A	1.301	1.00
57_Y	61_D	1.299	1.00
115_I	118_E	1.298	1.00
141_Y	145_L	1.296	1.00
439_S	488_T	1.294	1.00
218_A	222_F	1.294	1.00
436_G	441_G	1.292	1.00
142_A	145_L	1.288	1.00
352_L	357_L	1.285	1.00
86_Y	89_T	1.283	1.00
395_A	398_L	1.277	1.00
85_H	91_D	1.262	1.00
346_L	353_I	1.258	1.00
105_H	111_I	1.256	1.00
198_Q	201_A	1.256	1.00
493_T	497_G	1.255	1.00
350_D	353_I	1.255	1.00
306_L	310_A	1.254	1.00
351_A	355_D	1.250	1.00
204_A	207_A	1.248	1.00
120_H	124_G	1.239	1.00
149_Q	152_T	1.237	1.00
298_E	301_R	1.235	1.00
51_V	55_L	1.233	1.00
412_F	416_F	1.229	1.00
219_W	223_E	1.225	1.00
47_A	51_V	1.224	1.00
200_D	203_A	1.220	1.00
205_L	208_D	1.219	1.00
377_V	382_W	1.219	1.00
49_Q	53_R	1.218	1.00
52_H	59_P	1.213	1.00
353_I	357_L	1.212	1.00
441_G	490_D	1.206	1.00
86_Y	92_R	1.199	1.00
65_D	70_I	1.197	1.00
180_V	264_G	1.196	1.00
460_F	489_I	1.195	1.00
86_Y	90_G	1.194	1.00
324_A	342_L	1.193	1.00
143_A	146_E	1.191	1.00
332_K	336_D	1.190	1.00
100_E	139_K	1.187	1.00
199_S	202_A	1.184	1.00
39_D	45_R	1.181	1.00
159_R	296_E	1.180	1.00
323_T	345_A	1.177	1.00
328_V	339_L	1.174	1.00
289_A	293_A	1.172	1.00
102_P	112_Q	1.161	1.00
379_A	382_W	1.160	1.00
198_Q	202_A	1.155	1.00
378_A	433_A	1.141	1.00
454_T	457_A	1.131	1.00
299_R	302_Q	1.128	1.00
269_V	275_T	1.128	1.00
148_L	151_I	1.124	1.00
132_M	135_V	1.118	1.00
448_G	457_A	1.118	1.00
336_D	345_A	1.115	1.00
356_V	361_K	1.113	1.00
378_A	381_A	1.108	1.00
112_Q	115_I	1.106	1.00
340_T	343_T	1.105	1.00
216_S	222_F	1.102	1.00
349_M	360_A	1.099	1.00
493_T	496_S	1.099	1.00
219_W	222_F	1.091	1.00
482_A	489_I	1.087	1.00
491_A	499_A	1.087	1.00
73_P	76_H	1.085	1.00
374_V	442_F	1.085	1.00
113_L	118_E	1.084	1.00
415_L	503_I	1.076	1.00
34_A	132_M	1.076	1.00
317_L	321_L	1.073	1.00
483_T	488_T	1.072	1.00
139_K	143_A	1.070	1.00
97_N	100_E	1.069	1.00
458_Q	461_D	1.069	1.00
455_D	464_Y	1.062	1.00
372_V	380_D	1.062	1.00
197_A	202_A	1.061	1.00
39_D	43_T	1.061	1.00
222_F	225_N	1.058	1.00
492_T	502_T	1.058	1.00
372_V	376_S	1.058	1.00
143_A	147_S	1.055	1.00
314_S	318_R	1.053	1.00
172_A	282_L	1.052	1.00
196_V	202_A	1.051	1.00
302_Q	307_E	1.050	1.00
319_D	323_T	1.047	1.00
238_T	241_H	1.046	1.00
135_V	139_K	1.046	1.00
161_P	290_L	1.042	1.00
221_A	227_S	1.042	1.00
112_Q	116_T	1.039	1.00
101_M	104_Q	1.039	1.00
407_R	481_I	1.029	1.00
319_D	322_Q	1.028	1.00
218_A	260_V	1.025	1.00
314_S	320_P	1.021	1.00
346_L	352_L	1.018	1.00
144_T	147_S	1.015	1.00
358_T	361_K	1.011	1.00
315_H	320_P	1.002	1.00
329_A	332_K	1.000	1.00
111_I	117_F	0.998	1.00
372_V	377_V	0.996	1.00
114_S	138_Q	0.991	1.00
385_A	420_V	0.988	1.00
72_P	102_P	0.987	1.00
338_A	342_L	0.987	1.00
71_M	74_R	0.986	1.00
388_P	391_S	0.985	1.00
346_L	350_D	0.984	1.00
85_H	88_E	0.983	1.00
252_A	262_L	0.981	1.00
458_Q	464_Y	0.979	1.00
351_A	354_A	0.973	1.00
44_I	62_L	0.972	1.00
114_S	133_R	0.970	1.00
490_D	504_H	0.965	1.00
310_A	322_Q	0.965	1.00
304_E	308_R	0.963	1.00
382_W	392_L	0.960	1.00
356_V	360_A	0.960	1.00
430_T	447_D	0.959	1.00
343_T	347_D	0.959	1.00
225_N	256_G	0.959	1.00
98_A	114_S	0.957	1.00
395_A	399_P	0.956	1.00
336_D	340_T	0.954	1.00
79_H	92_R	0.951	1.00
101_M	115_I	0.949	1.00
192_V	195_P	0.948	1.00
171_A	175_I	0.945	1.00
342_L	346_L	0.944	1.00
169_V	183_L	0.938	1.00
158_A	167_H	0.936	1.00
448_G	452_G	0.934	1.00
119_E	125_V	0.931	1.00
171_A	174_D	0.927	1.00
369_T	485_H	0.927	1.00
317_L	352_L	0.927	1.00
375_A	379_A	0.924	1.00
373_P	378_A	0.922	1.00
325_R	350_D	0.920	1.00
339_L	342_L	0.919	1.00
98_A	103_G	0.918	1.00
80_F	86_Y	0.917	1.00
127_A	130_G	0.916	1.00
114_S	118_E	0.914	1.00
341_D	344_A	0.911	1.00
259_G	287_Q	0.908	1.00
311_S	318_R	0.907	1.00
79_H	86_Y	0.903	1.00
151_I	282_L	0.903	1.00
357_L	363_G	0.901	1.00
375_A	378_A	0.899	1.00
330_L	333_A	0.898	1.00
316_D	319_D	0.897	1.00
217_L	222_F	0.897	1.00
338_A	341_D	0.893	1.00
342_L	345_A	0.893	1.00
349_M	356_V	0.892	1.00
112_Q	139_K	0.892	1.00
221_A	228_A	0.891	1.00
114_S	117_F	0.889	1.00
449_D	468_T	0.887	1.00
191_G	196_V	0.885	1.00
113_L	116_T	0.885	1.00
398_L	404_D	0.883	1.00
220_H	229_V	0.881	1.00
288_A	292_R	0.881	1.00
459_L	501_F	0.878	0.99
380_D	383_S	0.878	0.99
459_L	491_A	0.877	0.99
49_Q	52_H	0.876	0.99
448_G	453_D	0.876	0.99
221_A	230_Y	0.875	0.99
327_T	338_A	0.873	0.99
34_A	51_V	0.873	0.99
197_A	200_D	0.870	0.99
38_I	42_S	0.869	0.99
196_V	203_A	0.868	0.99
448_G	451_F	0.867	0.99
112_Q	117_F	0.865	0.99
451_F	457_A	0.862	0.99
233_D	248_I	0.861	0.99
193_L	197_A	0.859	0.99
355_D	358_T	0.858	0.99
78_A	82_A	0.857	0.99
195_P	199_S	0.852	0.99
335_D	339_L	0.851	0.99
311_S	314_S	0.849	0.99
216_S	221_A	0.846	0.99
220_H	223_E	0.845	0.99
120_H	125_V	0.845	0.99
354_A	357_L	0.845	0.99
38_I	83_V	0.840	0.99
345_A	352_L	0.840	0.99
217_L	220_H	0.838	0.99
29_E	49_Q	0.837	0.99
327_T	341_D	0.836	0.99
120_H	123_N	0.832	0.99
448_G	454_T	0.832	0.99
329_A	343_T	0.831	0.99
71_M	76_H	0.831	0.99
197_A	203_A	0.827	0.99
134_D	138_Q	0.827	0.99
255_L	283_A	0.826	0.99
113_L	117_F	0.825	0.99
336_D	341_D	0.825	0.99
173_V	181_A	0.823	0.99
100_E	104_Q	0.822	0.99
44_I	63_I	0.818	0.99
353_I	358_T	0.818	0.99
389_T	393_S	0.817	0.99
451_F	454_T	0.816	0.99
158_A	164_I	0.813	0.99
216_S	220_H	0.812	0.99
456_T	459_L	0.809	0.99
374_V	381_A	0.808	0.99
224_T	228_A	0.808	0.99
49_Q	59_P	0.807	0.99
381_A	385_A	0.806	0.99
68_T	71_M	0.804	0.99
385_A	413_E	0.804	0.99
35_I	48_N	0.802	0.99
101_M	105_H	0.802	0.99
453_D	457_A	0.802	0.99
78_A	83_V	0.801	0.99
103_G	106_A	0.800	0.99
79_H	83_V	0.799	0.99
338_A	343_T	0.798	0.99
376_S	379_A	0.797	0.99
358_T	365_T	0.797	0.99
299_R	305_Q	0.795	0.99
115_I	119_E	0.795	0.99
83_V	92_R	0.791	0.99
402_N	405_P	0.789	0.99
37_T	40_D	0.788	0.99
219_W	227_S	0.787	0.99
449_D	493_T	0.786	0.99
384_T	409_R	0.785	0.99
309_F	315_H	0.785	0.99
182_S	185_R	0.784	0.99
47_A	62_L	0.784	0.99
191_G	198_Q	0.784	0.99
82_A	85_H	0.781	0.99
488_T	504_H	0.779	0.99
372_V	375_A	0.778	0.99
165_G	171_A	0.774	0.99
325_R	329_A	0.774	0.99
82_A	91_D	0.774	0.99
112_Q	118_E	0.773	0.99
315_H	319_D	0.773	0.99
74_R	79_H	0.770	0.99
450_G	454_T	0.769	0.99
396_P	399_P	0.767	0.99
368_E	371_P	0.765	0.99
453_D	494_S	0.765	0.99
99_I	103_G	0.760	0.99
129_S	132_M	0.758	0.99
422_H	467_D	0.756	0.98
219_W	225_N	0.755	0.98
27_L	31_G	0.755	0.98
337_D	340_T	0.755	0.98
378_A	382_W	0.754	0.98
154_T	167_H	0.753	0.98
112_Q	119_E	0.752	0.98
346_L	357_L	0.750	0.98
195_P	198_Q	0.747	0.98
369_T	402_N	0.746	0.98
421_A	465_T	0.745	0.98
388_P	392_L	0.745	0.98
183_L	255_L	0.744	0.98
332_K	339_L	0.744	0.98
285_N	289_A	0.743	0.98
335_D	341_D	0.739	0.98
178_F	181_A	0.738	0.98
331_A	342_L	0.737	0.98
354_A	360_A	0.737	0.98
78_A	90_G	0.736	0.98
346_L	356_V	0.736	0.98
136_S	139_K	0.734	0.98
423_G	426_D	0.733	0.98
131_I	134_D	0.731	0.98
465_T	468_T	0.731	0.98
392_L	398_L	0.731	0.98
97_N	105_H	0.730	0.98
199_S	203_A	0.730	0.98
338_A	344_A	0.727	0.98
221_A	224_T	0.727	0.98
309_F	314_S	0.726	0.98
78_A	86_Y	0.726	0.98
82_A	86_Y	0.726	0.98
376_S	382_W	0.726	0.98
348_R	354_A	0.725	0.98
375_A	385_A	0.725	0.98
343_T	346_L	0.723	0.98
374_V	378_A	0.723	0.98
87_L	91_D	0.720	0.98
451_F	491_A	0.718	0.98
455_D	466_T	0.718	0.98
330_L	338_A	0.717	0.98
331_A	334_G	0.717	0.98
327_T	332_K	0.716	0.98
37_T	42_S	0.716	0.98
350_D	357_L	0.714	0.98
299_R	307_E	0.714	0.98
113_L	132_M	0.713	0.98
380_D	409_R	0.713	0.98
310_A	315_H	0.710	0.98
31_G	37_T	0.707	0.98
152_T	156_M	0.707	0.98
372_V	385_A	0.706	0.98
167_H	171_A	0.705	0.98
87_L	92_R	0.704	0.98
348_R	353_I	0.703	0.98
257_E	287_Q	0.702	0.98
134_D	139_K	0.702	0.98
135_V	138_Q	0.701	0.98
115_I	132_M	0.700	0.98
180_V	184_Y	0.700	0.98
164_I	168_V	0.698	0.97
44_I	47_A	0.698	0.97
86_Y	91_D	0.697	0.97
34_A	50_G	0.696	0.97
195_P	200_D	0.696	0.97
349_M	354_A	0.696	0.97
312_I	316_D	0.695	0.97
151_I	156_M	0.694	0.97
113_L	119_E	0.693	0.97
110_E	114_S	0.693	0.97
191_G	194_R	0.692	0.97
172_A	263_V	0.691	0.97
291_E	295_R	0.690	0.97
97_N	101_M	0.690	0.97
331_A	339_L	0.686	0.97
448_G	455_D	0.685	0.97
316_D	352_L	0.685	0.97
81_D	84_D	0.678	0.97
314_S	357_L	0.676	0.97
371_P	400_T	0.675	0.97
80_F	83_V	0.674	0.97
297_A	307_E	0.674	0.97
306_L	421_A	0.674	0.97
379_A	386_G	0.673	0.97
76_H	79_H	0.673	0.97
335_D	338_A	0.672	0.97
411_L	485_H	0.672	0.97
327_T	333_A	0.671	0.97
182_S	264_G	0.670	0.97
390_A	394_T	0.670	0.97
416_F	431_V	0.670	0.97
218_A	221_A	0.669	0.97
197_A	201_A	0.668	0.97
117_F	130_G	0.666	0.97
139_K	145_L	0.665	0.97
400_T	405_P	0.661	0.97
390_A	393_S	0.661	0.97
117_F	128_F	0.660	0.96
263_V	279_I	0.660	0.96
210_P	214_A	0.659	0.96
34_A	48_N	0.658	0.96
134_D	137_R	0.658	0.96
280_E	284_A	0.657	0.96
345_A	348_R	0.655	0.96
265_D	269_V	0.655	0.96
271_F	276_S	0.654	0.96
404_D	409_R	0.654	0.96
36_V	47_A	0.653	0.96
405_P	410_T	0.652	0.96
379_A	383_S	0.652	0.96
330_L	334_G	0.652	0.96
47_A	52_H	0.650	0.96
57_Y	105_H	0.649	0.96
327_T	334_G	0.648	0.96
222_F	227_S	0.648	0.96
173_V	271_F	0.647	0.96
104_Q	110_E	0.646	0.96
465_T	469_D	0.646	0.96
47_A	55_L	0.645	0.96
261_L	283_A	0.644	0.96
367_G	404_D	0.643	0.96
325_R	328_V	0.643	0.96
187_D	190_T	0.641	0.96
352_L	360_A	0.640	0.96
221_A	225_N	0.639	0.96
162_G	166_D	0.638	0.96
150_D	153_H	0.638	0.96
352_L	356_V	0.637	0.96
452_G	466_T	0.637	0.96
418_N	450_G	0.635	0.96
406_E	409_R	0.635	0.96
310_A	314_S	0.635	0.96
189_A	192_V	0.634	0.96
66_S	70_I	0.634	0.96
452_G	457_A	0.633	0.96
313_V	319_D	0.632	0.96
373_P	379_A	0.632	0.96
423_G	465_T	0.631	0.95
75_F	78_A	0.630	0.95
78_A	81_D	0.630	0.95
76_H	80_F	0.629	0.95
262_L	265_D	0.629	0.95
352_L	355_D	0.629	0.95
38_I	44_I	0.627	0.95
38_I	117_F	0.623	0.95
404_D	408_L	0.621	0.95
227_S	280_E	0.620	0.95
374_V	380_D	0.619	0.95
319_D	349_M	0.617	0.95
149_Q	153_H	0.616	0.95
411_L	415_L	0.614	0.95
243_P	246_P	0.613	0.95
366_V	369_T	0.613	0.95
52_H	62_L	0.612	0.95
373_P	381_A	0.612	0.95
55_L	62_L	0.610	0.95
66_S	71_M	0.610	0.95
71_M	75_F	0.608	0.94
52_H	55_L	0.608	0.94
378_A	442_F	0.607	0.94
102_P	110_E	0.607	0.94
236_A	240_V	0.603	0.94
68_T	72_P	0.603	0.94
104_Q	107_D	0.602	0.94
473_F	477_I	0.600	0.94
198_Q	204_A	0.599	0.94
151_I	171_A	0.598	0.94
161_P	165_G	0.597	0.94
300_E	303_N	0.597	0.94
348_R	357_L	0.597	0.94
98_A	116_T	0.596	0.94
331_A	335_D	0.596	0.94
27_L	30_H	0.596	0.94
307_E	349_M	0.596	0.94
105_H	108_G	0.595	0.94
140_A	144_T	0.595	0.94
182_S	262_L	0.595	0.94
318_R	350_D	0.594	0.94
302_Q	306_L	0.592	0.94
315_H	318_R	0.591	0.94
353_I	359_L	0.589	0.93
326_A	331_A	0.589	0.93
128_F	132_M	0.589	0.93
194_R	197_A	0.586	0.93
414_N	417_G	0.586	0.93
141_Y	144_T	0.586	0.93
383_S	386_G	0.586	0.93
78_A	85_H	0.585	0.93
99_I	104_Q	0.585	0.93
417_G	421_A	0.583	0.93
353_I	361_K	0.581	0.93
37_T	127_A	0.580	0.93
415_L	501_F	0.579	0.93
467_D	470_G	0.578	0.93
84_D	87_L	0.578	0.93
255_L	258_H	0.578	0.93
369_T	403_A	0.577	0.93
325_R	347_D	0.577	0.93
79_H	87_L	0.576	0.93
80_F	90_G	0.576	0.93
451_F	499_A	0.575	0.93
79_H	91_D	0.575	0.93
345_A	350_D	0.571	0.92
436_G	439_S	0.569	0.92
312_I	319_D	0.569	0.92
82_A	89_T	0.567	0.92
285_N	288_A	0.566	0.92
339_L	343_T	0.566	0.92
110_E	113_L	0.566	0.92
46_Y	49_Q	0.565	0.92
418_N	474_G	0.563	0.92
101_M	132_M	0.562	0.92
289_A	295_R	0.561	0.92
375_A	382_W	0.560	0.92
164_I	167_H	0.560	0.92
191_G	197_A	0.559	0.92
345_A	353_I	0.559	0.92
417_G	422_H	0.559	0.92
122_H	125_V	0.558	0.92
112_Q	136_S	0.556	0.91
101_M	112_Q	0.556	0.91
154_T	170_G	0.555	0.91
154_T	157_Q	0.554	0.91
37_T	45_R	0.553	0.91
411_L	503_I	0.553	0.91
57_Y	70_I	0.553	0.91
173_V	180_V	0.553	0.91
335_D	342_L	0.552	0.91
109_H	116_T	0.552	0.91
98_A	101_M	0.552	0.91
327_T	345_A	0.551	0.91
43_T	47_A	0.551	0.91
163_A	167_H	0.550	0.91
364_Q	367_G	0.550	0.91
378_A	412_F	0.550	0.91
345_A	349_M	0.550	0.91
214_A	217_L	0.549	0.91
193_L	199_S	0.547	0.91
111_I	116_T	0.547	0.91
67_L	72_P	0.546	0.91
450_G	498_G	0.546	0.91
38_I	67_L	0.545	0.91
104_Q	108_G	0.545	0.91
422_H	447_D	0.543	0.90
312_I	317_L	0.543	0.90
463_G	471_T	0.543	0.90
281_L	285_N	0.542	0.90
317_L	353_I	0.541	0.90
250_E	264_G	0.541	0.90
318_R	357_L	0.541	0.90
356_V	359_L	0.538	0.90
316_D	414_N	0.538	0.90
154_T	171_A	0.538	0.90
401_L	407_R	0.536	0.90
118_E	131_I	0.535	0.90
196_V	200_D	0.534	0.90
111_I	118_E	0.534	0.90
203_A	207_A	0.533	0.90
450_G	457_A	0.533	0.90
169_V	182_S	0.533	0.90
466_T	470_G	0.532	0.90
327_T	331_A	0.530	0.89
398_L	433_A	0.530	0.89
416_F	420_V	0.530	0.89
227_S	231_H	0.529	0.89
126_R	130_G	0.529	0.89
376_S	385_A	0.529	0.89
196_V	201_A	0.528	0.89
324_A	328_V	0.528	0.89
44_I	65_D	0.527	0.89
98_A	102_P	0.524	0.89
446_D	498_G	0.524	0.89
317_L	320_P	0.523	0.89
47_A	59_P	0.523	0.89
374_V	385_A	0.522	0.89
349_M	355_D	0.522	0.89
341_D	353_I	0.522	0.89
358_T	407_R	0.522	0.89
71_M	103_G	0.521	0.89
401_L	409_R	0.520	0.88
76_H	86_Y	0.520	0.88
35_I	46_Y	0.519	0.88
385_A	417_G	0.518	0.88
311_S	320_P	0.516	0.88
322_Q	330_L	0.516	0.88
68_T	76_H	0.512	0.88
247_M	252_A	0.511	0.88
46_Y	51_V	0.511	0.88
78_A	91_D	0.508	0.87
72_P	110_E	0.508	0.87
221_A	226_D	0.508	0.87
43_T	64_G	0.507	0.87
100_E	105_H	0.507	0.87
37_T	46_Y	0.507	0.87
469_D	473_F	0.506	0.87
334_G	338_A	0.506	0.87
37_T	48_N	0.506	0.87
259_G	264_G	0.504	0.87
335_D	345_A	0.504	0.87
28_V	48_N	0.503	0.87
478_V	503_I	0.503	0.87
291_E	296_E	0.502	0.87
114_S	119_E	0.502	0.87
118_E	129_S	0.501	0.87
102_P	106_A	0.501	0.87
255_L	259_G	0.500	0.86

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4gczA	2	0.6838	100	0.447	Contact Map
4i5sA	2	0.6502	100	0.474	Contact Map
3a0rA	2	0.6166	100	0.482	Contact Map
4r3aA	1	0.587	100	0.545	Contact Map
4mpcA	2	0.5534	100	0.608	Contact Map
4q20A	2	0.4269	100	0.609	Contact Map
4ctiA	2	0.4368	100	0.61	Contact Map
2q8gA	2	0.5375	100	0.616	Contact Map
3d36A	2	0.4091	100	0.617	Contact Map
3jz3A	2	0.2905	100	0.621	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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