Q9HNL8 - HALSA - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

Q9HNL8 - HAM1 protein homolog

UniProt:	Q9HNL8	Sequences: MSTLRFVTTNSGKVQEAASYLDGLRRVEQLDYDYAELQSDDLAAIATHGAREAYRETDDDTPVIVDDAGLFVRGLSGFPGPYSAYVEDTLGIERVWELASDLDDRHAAFRCVVAYTDGDTVETFTGAVQGTMVAPRGDGGFGYDPIFEHDGTTFAEMPTDRKNALSHRGRALATFADWLAERAD	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	184 (176)
Sequences:	4618 (3263)
Seq/√Len:	246.0

ECOLI - RDGB
BACSU - NTPA
HALSA - Q9HNL8
SULSO - NTPA

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
39_S	44_A	3.336	1.00
128_V	154_F	3.095	1.00
136_R	156_E	2.947	1.00
78_F	98_L	2.688	1.00
92_I	146_I	2.587	1.00
34_Y	37_L	2.578	1.00
38_Q	48_H	2.565	1.00
71_F	108_A	2.436	1.00
158_P	161_R	2.428	1.00
108_A	127_A	2.327	1.00
133_V	153_T	2.269	1.00
46_A	114_A	2.263	1.00
94_R	98_L	2.254	1.00
124_F	178_W	2.235	1.00
152_T	161_R	2.234	1.00
108_A	129_Q	2.178	1.00
73_R	106_H	2.168	1.00
87_E	90_L	2.131	1.00
86_V	98_L	2.012	1.00
73_R	108_A	2.000	1.00
3_T	61_T	1.989	1.00
71_F	110_R	1.970	1.00
12_G	15_Q	1.962	1.00
72_V	95_V	1.946	1.00
43_A	125_T	1.925	1.00
97_E	100_S	1.923	1.00
110_R	125_T	1.886	1.00
73_R	104_D	1.859	1.00
26_R	29_Q	1.833	1.00
93_E	135_P	1.803	1.00
26_R	30_L	1.751	1.00
89_T	135_P	1.735	1.00
89_T	93_E	1.689	1.00
47_T	51_R	1.682	1.00
19_S	163_N	1.626	1.00
51_R	121_V	1.625	1.00
133_V	148_E	1.579	1.00
114_A	123_T	1.549	1.00
169_G	173_A	1.528	1.00
3_T	28_E	1.507	1.00
62_P	115_Y	1.495	1.00
6_F	17_A	1.485	1.00
170_R	173_A	1.474	1.00
47_T	121_V	1.454	1.00
47_T	123_T	1.451	1.00
92_I	135_P	1.442	1.00
133_V	136_R	1.430	1.00
78_F	86_V	1.427	1.00
22_D	25_R	1.427	1.00
51_R	55_R	1.420	1.00
40_D	44_A	1.413	1.00
50_A	114_A	1.382	1.00
42_L	71_F	1.377	1.00
5_R	53_A	1.371	1.00
122_E	178_W	1.370	1.00
148_E	151_G	1.336	1.00
161_R	164_A	1.334	1.00
93_E	97_E	1.320	1.00
115_Y	175_F	1.295	1.00
3_T	26_R	1.259	1.00
43_A	123_T	1.257	1.00
96_W	146_I	1.226	1.00
52_E	56_E	1.222	1.00
54_Y	116_T	1.220	1.00
157_M	161_R	1.209	1.00
57_T	61_T	1.169	1.00
8_T	14_V	1.168	1.00
42_L	68_A	1.158	1.00
57_T	63_V	1.137	1.00
152_T	157_M	1.136	1.00
110_R	127_A	1.125	1.00
88_D	91_G	1.108	1.00
57_T	60_D	1.102	1.00
5_R	61_T	1.100	1.00
54_Y	117_D	1.090	1.00
43_A	114_A	1.086	1.00
107_A	132_M	1.081	1.00
129_Q	150_D	1.071	1.00
91_G	94_R	1.071	1.00
53_A	63_V	1.063	1.00
17_A	113_V	1.058	1.00
47_T	114_A	1.046	1.00
48_H	52_E	1.043	1.00
11_S	15_Q	1.042	1.00
174_T	177_D	1.016	1.00
14_V	29_Q	1.012	1.00
64_I	113_V	1.009	1.00
70_L	132_M	0.993	1.00
23_G	176_A	0.990	1.00
116_T	121_V	0.990	1.00
39_S	48_H	0.987	1.00
124_F	175_F	0.976	1.00
73_R	77_G	0.972	1.00
50_A	116_T	0.962	1.00
95_V	146_I	0.952	1.00
64_I	175_F	0.949	1.00
90_L	93_E	0.946	1.00
139_G	158_P	0.945	1.00
113_V	175_F	0.945	1.00
92_I	145_P	0.931	1.00
47_T	116_T	0.930	1.00
96_W	105_R	0.926	1.00
174_T	178_W	0.919	1.00
51_R	116_T	0.911	1.00
154_F	157_M	0.908	1.00
176_A	180_A	0.905	1.00
5_R	63_V	0.900	1.00
106_H	129_Q	0.893	1.00
173_A	176_A	0.884	1.00
74_G	102_L	0.882	1.00
112_V	125_T	0.878	1.00
37_L	52_E	0.876	0.99
83_S	143_Y	0.873	0.99
68_A	111_C	0.872	0.99
32_Y	37_L	0.865	0.99
41_D	81_P	0.864	0.99
131_T	148_E	0.864	0.99
14_V	18_A	0.863	0.99
33_D	37_L	0.857	0.99
112_V	123_T	0.848	0.99
12_G	17_A	0.847	0.99
131_T	150_D	0.846	0.99
113_V	172_L	0.840	0.99
45_I	81_P	0.839	0.99
137_G	155_A	0.835	0.99
128_V	165_L	0.832	0.99
124_F	174_T	0.829	0.99
133_V	146_I	0.826	0.99
91_G	95_V	0.824	0.99
19_S	159_T	0.821	0.99
128_V	170_R	0.804	0.99
87_E	91_G	0.802	0.99
52_E	55_R	0.801	0.99
96_W	133_V	0.801	0.99
5_R	57_T	0.793	0.99
86_V	94_R	0.782	0.99
173_A	177_D	0.779	0.99
92_I	95_V	0.758	0.99
149_H	157_M	0.758	0.99
81_P	85_Y	0.757	0.99
19_S	22_D	0.756	0.99
17_A	172_L	0.754	0.98
151_G	161_R	0.753	0.98
117_D	120_T	0.740	0.98
144_D	162_K	0.736	0.98
15_Q	19_S	0.732	0.98
27_V	30_L	0.732	0.98
6_F	64_I	0.727	0.98
101_D	105_R	0.726	0.98
102_L	105_R	0.725	0.98
99_A	132_M	0.720	0.98
106_H	131_T	0.711	0.98
92_I	96_W	0.710	0.98
37_L	48_H	0.705	0.98
102_L	106_H	0.699	0.98
31_D	37_L	0.698	0.98
15_Q	18_A	0.694	0.97
17_A	21_L	0.692	0.97
177_D	180_A	0.690	0.97
41_D	44_A	0.690	0.97
131_T	151_G	0.689	0.97
73_R	129_Q	0.689	0.97
40_D	82_Y	0.688	0.97
162_K	166_S	0.688	0.97
88_D	95_V	0.684	0.97
40_D	81_P	0.675	0.97
12_G	88_D	0.673	0.97
138_D	156_E	0.673	0.97
31_D	34_Y	0.667	0.97
94_R	97_E	0.667	0.97
70_L	109_F	0.666	0.97
15_Q	159_T	0.664	0.97
68_A	92_I	0.663	0.97
111_C	171_A	0.660	0.97
126_G	170_R	0.659	0.96
112_V	124_F	0.659	0.96
11_S	18_A	0.656	0.96
154_F	165_L	0.655	0.96
16_E	162_K	0.655	0.96
20_Y	159_T	0.653	0.96
42_L	110_R	0.653	0.96
170_R	174_T	0.652	0.96
153_T	156_E	0.648	0.96
16_E	163_N	0.647	0.96
109_F	154_F	0.645	0.96
35_A	56_E	0.642	0.96
141_F	162_K	0.639	0.96
109_F	146_I	0.639	0.96
64_I	115_Y	0.636	0.96
32_Y	35_A	0.631	0.96
54_Y	62_P	0.627	0.95
38_Q	81_P	0.627	0.95
98_L	101_D	0.625	0.95
99_A	105_R	0.625	0.95
152_T	156_E	0.622	0.95
109_F	143_Y	0.621	0.95
151_G	165_L	0.617	0.95
35_A	48_H	0.614	0.95
34_Y	53_A	0.613	0.95
136_R	152_T	0.612	0.95
24_L	180_A	0.609	0.95
9_T	30_L	0.609	0.95
115_Y	122_E	0.606	0.94
34_Y	49_G	0.604	0.94
20_Y	113_V	0.603	0.94
137_G	141_F	0.601	0.94
141_F	144_D	0.601	0.94
60_D	63_V	0.590	0.94
164_A	169_G	0.589	0.94
54_Y	63_V	0.589	0.94
46_A	123_T	0.588	0.93
55_R	60_D	0.586	0.93
12_G	20_Y	0.586	0.93
175_F	179_L	0.586	0.93
132_M	146_I	0.579	0.93
152_T	158_P	0.579	0.93
4_L	115_Y	0.578	0.93
42_L	69_G	0.576	0.93
96_W	99_A	0.576	0.93
135_P	145_P	0.575	0.93
105_R	132_M	0.574	0.93
20_Y	172_L	0.574	0.93
136_R	153_T	0.572	0.93
19_S	160_D	0.561	0.92
34_Y	52_E	0.559	0.92
18_A	22_D	0.556	0.91
88_D	92_I	0.556	0.91
76_S	79_P	0.551	0.91
89_T	92_I	0.548	0.91
43_A	112_V	0.545	0.91
137_G	140_G	0.541	0.90
90_L	94_R	0.539	0.90
66_D	113_V	0.538	0.90
9_T	53_A	0.538	0.90
35_A	52_E	0.535	0.90
104_D	131_T	0.532	0.90
105_R	133_V	0.530	0.89
114_A	121_V	0.530	0.89
125_T	174_T	0.530	0.89
163_N	166_S	0.529	0.89
71_F	77_G	0.529	0.89
21_L	176_A	0.528	0.89
116_T	119_D	0.525	0.89
42_L	81_P	0.524	0.89
112_V	126_G	0.523	0.89
157_M	165_L	0.520	0.89
16_E	168_R	0.519	0.88
155_A	163_N	0.519	0.88
135_P	146_I	0.518	0.88
150_D	170_R	0.518	0.88
111_C	167_H	0.516	0.88
11_S	14_V	0.516	0.88
151_G	157_M	0.514	0.88
62_P	117_D	0.512	0.88
9_T	29_Q	0.509	0.87
72_V	75_L	0.509	0.87
141_F	145_P	0.509	0.87
103_D	131_T	0.507	0.87
54_Y	61_T	0.506	0.87
20_Y	163_N	0.506	0.87
91_G	146_I	0.503	0.87
68_A	83_S	0.502	0.87
72_V	107_A	0.501	0.87
32_Y	53_A	0.500	0.87

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1v7rA	1	0.9837	100	0.073	Contact Map
1b78A	2	0.9674	100	0.079	Contact Map
2carA	2	0.9837	100	0.083	Contact Map
1k7kA	1	0.9783	100	0.101	Contact Map
1vp2A	3	0.9674	100	0.117	Contact Map
3tquA	2	0.9783	100	0.137	Contact Map
4bnqA	2	0.9837	100	0.154	Contact Map
1ex2A	2	0.8207	96.1	0.892	Contact Map
4jhcA	2	0.8261	96	0.893	Contact Map
4p0eA	2	0.8207	95.4	0.898	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0074 seconds.