GREMLIN Database
RS24 - 30S ribosomal protein S24e
UniProt: Q9HNL4 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 102 (97)
Sequences: 162 (124)
Seq/√Len: 12.6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
8_Q17_T4.3691.00
32_R88_R4.0341.00
21_F66_G3.7970.99
25_H64_T3.4610.99
77_A86_L2.4460.89
43_L70_V2.1080.80
38_S42_K2.0820.79
25_H57_T1.9840.76
84_H88_R1.8920.72
52_V92_G1.8060.69
45_K62_R1.7560.66
55_L64_T1.7050.64
14_L59_F1.6810.63
21_F68_A1.6750.63
46_D74_P1.6600.62
74_P78_A1.6450.61
13_L18_D1.6310.60
53_H67_R1.6260.60
23_I50_V1.6160.60
39_L50_V1.5380.56
87_E90_K1.5360.56
40_A88_R1.5330.56
83_D87_E1.5040.54
52_V68_A1.5020.54
22_K63_K1.4660.52
47_S88_R1.3640.47
49_E74_P1.3440.46
10_D72_D1.2990.44
34_S77_A1.2750.42
32_R84_H1.2570.41
14_L80_V1.2490.41
53_H57_T1.1920.38
38_S41_A1.1660.37
12_P87_E1.1570.37
86_L91_I1.1550.36
23_I96_A1.1340.35
5_I43_L1.1290.35
42_K77_A1.1160.35
7_G48_E1.1100.34
36_R89_N1.0930.34
5_I8_Q1.0790.33
59_F72_D1.0490.32
48_E74_P1.0490.32
58_K61_M1.0380.31
4_E19_V1.0290.31
76_Q79_E1.0200.30
29_T40_A1.0150.30
41_A74_P0.9970.29
50_V77_A0.9960.29
4_E65_R0.9960.29
57_T88_R0.9860.29
46_D94_D0.9770.28
2_E48_E0.9590.28
45_K57_T0.9430.27
19_V58_K0.9350.27
31_S55_L0.9220.26
39_L68_A0.9190.26
5_I75_A0.9160.26
2_E23_I0.9060.26
77_A89_N0.9060.26
55_L91_I0.8950.25
40_A64_T0.8870.25
35_V39_L0.8850.25
8_Q83_D0.8780.24
42_K51_V0.8540.24
3_I37_D0.8540.24
34_S97_D0.8360.23
31_S87_E0.8310.23
9_E92_G0.8230.22
59_F62_R0.8170.22
38_S77_A0.8120.22
25_H40_A0.8060.22
46_D90_K0.8010.22
1_M41_A0.8000.22
32_R40_A0.7910.21
17_T70_V0.7840.21
87_E94_D0.7700.21
2_E77_A0.7670.21
36_R57_T0.7630.20
5_I86_L0.7430.20
42_K46_D0.7300.19
67_R86_L0.7290.19
31_S50_V0.7220.19
44_D82_H0.7170.19
28_A68_A0.7110.19
2_E9_E0.7110.19
35_V80_V0.7100.19
20_Q70_V0.7070.19
44_D78_A0.7020.18
37_D40_A0.6880.18
85_M88_R0.6810.18
52_V85_M0.6800.18
85_M89_N0.6760.18
41_A44_D0.6750.18
7_G54_E0.6670.17
58_K79_E0.6650.17
6_L65_R0.6570.17
40_A77_A0.6570.17
52_V67_R0.6550.17
48_E52_V0.6420.17
69_K89_N0.6400.17
4_E13_L0.6390.17
19_V73_S0.6370.16
53_H69_K0.6320.16
13_L82_H0.6290.16
59_F79_E0.6290.16
20_Q56_D0.6280.16
5_I95_D0.6170.16
40_A50_V0.6160.16
4_E54_E0.6110.16
14_L56_D0.6050.16
33_L95_D0.6020.16
77_A91_I0.5950.15
36_R88_R0.5850.15
19_V44_D0.5760.15
63_K73_S0.5740.15
40_A51_V0.5720.15
64_T68_A0.5710.15
16_R71_Y0.5650.15
60_G71_Y0.5650.15
11_N60_G0.5650.15
11_N16_R0.5650.15
11_N71_Y0.5650.15
16_R60_G0.5650.15
9_E53_H0.5640.15
67_R89_N0.5630.14
29_T44_D0.5580.14
87_E91_I0.5570.14
34_S37_D0.5560.14
6_L20_Q0.5480.14
41_A59_F0.5470.14
51_V80_V0.5470.14
22_K65_R0.5440.14
52_V89_N0.5400.14
4_E22_K0.5380.14
17_T44_D0.5300.14
32_R36_R0.5300.14
2_E14_L0.5290.14
82_H88_R0.5220.13
57_T82_H0.5180.13
36_R50_V0.5130.13
44_D69_K0.5120.13
84_H95_D0.5090.13
33_L63_K0.5080.13
46_D86_L0.5020.13
65_R78_A0.5000.13
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1xn9A 1 0.9902 100 0.157 Contact Map
1ywxA 1 1 100 0.158 Contact Map
2v94A 1 0.9118 100 0.182 Contact Map
2g1dA 1 0.951 100 0.185 Contact Map
4ujpZ 1 1 100 0.236 Contact Map
4bpeP 1 0.9902 100 0.24 Contact Map
3j7a1 1 1 100 0.244 Contact Map
3j60Y 1 1 100 0.246 Contact Map
3zeyT 1 1 100 0.251 Contact Map
4w23Y 1 1 100 0.259 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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