Q9HNK1 - HALSA - GREMLIN Contacts

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Q9HNK1 - Uncharacterized protein

UniProt:	Q9HNK1	Sequences: MLARQRARRDTTGGCAMSSGIIPVVATIIALGVLSQVVADKLQVPSVLFLILAGIVVGPEVLGVVTLSSFGGIDTLAGIVGLSVAVIVFEGAFHLKLEKLREAPGAWLRLVTVGAAIALFGTAIVVRVLLGTGWDVAFLIGSLLVATGPTVITPILSVVPVRDRVGAALETEGVVNDVTAAILAIVVFRVVENPQRSVDVVLQDFVTRLGTGVLVGLVVAAVVWYILRRIDLSKGNAPQNARLVVLAGALVAYGAADTLYSEAGIAAVATAGVLLGNADLPYEKEIEAFKGDVTLVVLSFVFIGLAALLSFQTLLDLGVAGLAVAVLVALVIRPLAVFASTARSRYTSAERVFMSAVGPRGIIPASVATLFAVELQGYGMPQAANVLVGTVFLTILLTVVFEGGFARHIAQALNVIPMRVIIVGGGTVGRALAERLEDRGENVVLVEDDPEAVERARNEGYTVHSGDGSDTDELRAAGAENAKILTAATGDDDVNLLVAQLADSKFDIDTIIARANNPDNIDAFEDLGVSTVSSSLATAWGIDNIIERPALSNWMTEIGRSGDVQEVEVTSEELVGLTIADLDDDLPGGVIIALAGRDGDNQVPNPEFTIQHGDHLTFLGRKEAVRDALNWCHPDDG	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	637 (508)
Sequences:	3394 (2376)
Seq/√Len:	105.4

ECOLI - KEFC KEFB YBAL
BACSU - YJBQ
HALSA - Q9HNK1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
485_L	502_A	5.166	1.00
395_I	399_V	4.998	1.00
399_V	403_G	4.411	1.00
394_T	399_V	3.973	1.00
399_V	402_E	3.640	1.00
395_I	402_E	3.269	1.00
409_I	412_A	3.028	1.00
395_I	403_G	3.016	1.00
395_I	398_T	2.983	1.00
393_L	399_V	2.859	1.00
487_A	499_A	2.838	1.00
422_I	433_A	2.815	1.00
389_G	399_V	2.815	1.00
391_V	395_I	2.784	1.00
386_V	399_V	2.669	1.00
363_I	366_S	2.624	1.00
360_R	364_P	2.624	1.00
359_P	363_I	2.579	1.00
399_V	406_A	2.577	1.00
359_P	362_I	2.545	1.00
203_Q	207_T	2.473	1.00
357_V	363_I	2.467	1.00
394_T	402_E	2.430	1.00
387_L	391_V	2.429	1.00
419_R	483_K	2.427	1.00
485_L	509_D	2.425	1.00
362_I	366_S	2.409	1.00
393_L	403_G	2.401	1.00
123_A	141_G	2.378	1.00
357_V	362_I	2.370	1.00
360_R	363_I	2.324	1.00
391_V	402_E	2.319	1.00
388_V	402_E	2.304	1.00
407_R	411_Q	2.302	1.00
338_F	355_S	2.293	1.00
394_T	403_G	2.290	1.00
389_G	395_I	2.268	1.00
323_A	327_L	2.259	1.00
394_T	398_T	2.248	1.00
384_A	399_V	2.209	1.00
398_T	403_G	2.144	1.00
386_V	403_G	2.118	1.00
206_V	210_G	2.111	1.00
398_T	402_E	2.076	1.00
388_V	399_V	2.050	1.00
399_V	405_F	2.034	1.00
359_P	364_P	2.031	1.00
417_P	481_N	2.021	1.00
391_V	399_V	2.005	1.00
387_L	399_V	1.980	1.00
499_A	529_V	1.970	1.00
388_V	395_I	1.953	1.00
388_V	403_G	1.933	1.00
390_T	399_V	1.902	1.00
503_D	530_S	1.901	1.00
392_F	399_V	1.886	1.00
384_A	395_I	1.881	1.00
202_L	206_V	1.875	1.00
500_Q	527_L	1.863	1.00
387_L	395_I	1.858	1.00
386_V	395_I	1.855	1.00
119_L	142_S	1.851	1.00
403_G	406_A	1.847	1.00
359_P	366_S	1.840	1.00
409_I	413_L	1.839	1.00
475_R	480_E	1.828	1.00
126_V	137_A	1.806	1.00
121_G	336_A	1.806	1.00
413_L	416_I	1.798	1.00
389_G	394_T	1.788	1.00
402_E	406_A	1.779	1.00
487_A	495_N	1.762	1.00
487_A	498_V	1.755	1.00
384_A	398_T	1.744	1.00
384_A	394_T	1.743	1.00
356_A	362_I	1.719	1.00
217_L	221_A	1.708	1.00
503_D	511_I	1.703	1.00
421_I	482_A	1.693	1.00
390_T	394_T	1.688	1.00
502_A	509_D	1.677	1.00
362_I	368_A	1.676	1.00
391_V	398_T	1.672	1.00
388_V	392_F	1.667	1.00
224_W	279_D	1.657	1.00
358_G	362_I	1.654	1.00
124_I	129_L	1.652	1.00
386_V	394_T	1.626	1.00
363_I	368_A	1.619	1.00
389_G	393_L	1.618	1.00
392_F	395_I	1.618	1.00
338_F	348_S	1.617	1.00
402_E	405_F	1.614	1.00
198_V	202_L	1.614	1.00
383_A	399_V	1.600	1.00
383_A	386_V	1.595	1.00
479_A	506_F	1.586	1.00
390_T	402_E	1.581	1.00
124_I	128_V	1.567	1.00
479_A	485_L	1.566	1.00
395_I	400_V	1.562	1.00
357_V	364_P	1.560	1.00
510_T	530_S	1.557	1.00
386_V	390_T	1.553	1.00
389_G	403_G	1.551	1.00
384_A	403_G	1.549	1.00
484_I	546_I	1.545	1.00
360_R	366_S	1.540	1.00
370_L	373_V	1.536	1.00
395_I	405_F	1.529	1.00
390_T	403_G	1.522	1.00
388_V	391_V	1.517	1.00
35_S	56_V	1.517	1.00
288_A	291_G	1.516	1.00
418_M	483_K	1.511	1.00
33_V	247_A	1.504	1.00
357_V	360_R	1.501	1.00
338_F	342_A	1.497	1.00
356_A	363_I	1.491	1.00
30_A	247_A	1.488	1.00
386_V	402_E	1.479	1.00
391_V	394_T	1.470	1.00
386_V	398_T	1.466	1.00
390_T	398_T	1.462	1.00
486_T	542_I	1.460	1.00
364_P	368_A	1.458	1.00
199_D	203_Q	1.455	1.00
390_T	395_I	1.433	1.00
142_S	183_L	1.433	1.00
385_N	389_G	1.427	1.00
398_T	405_F	1.423	1.00
393_L	398_T	1.422	1.00
394_T	406_A	1.415	1.00
395_I	406_A	1.405	1.00
421_I	479_A	1.404	1.00
328_V	332_I	1.402	1.00
408_H	412_A	1.397	1.00
391_V	403_G	1.397	1.00
387_L	398_T	1.394	1.00
412_A	416_I	1.391	1.00
123_A	138_F	1.388	1.00
357_V	366_S	1.367	1.00
392_F	403_G	1.366	1.00
423_V	485_L	1.364	1.00
491_D	494_V	1.363	1.00
383_A	387_L	1.360	1.00
389_G	398_T	1.359	1.00
394_T	405_F	1.352	1.00
117_I	121_G	1.348	0.99
356_A	359_P	1.343	0.99
285_E	290_K	1.337	0.99
314_L	389_G	1.336	0.99
360_R	368_A	1.331	0.99
358_G	363_I	1.327	0.99
383_A	395_I	1.322	0.99
387_L	390_T	1.316	0.99
389_G	402_E	1.315	0.99
31_L	57_V	1.311	0.99
204_D	207_T	1.309	0.99
384_A	402_E	1.308	0.99
123_A	134_W	1.307	0.99
389_G	392_F	1.306	0.99
533_S	536_L	1.303	0.99
396_L	399_V	1.303	0.99
383_A	391_V	1.296	0.99
358_G	368_A	1.295	0.99
428_V	542_I	1.292	0.99
383_A	403_G	1.289	0.99
120_F	124_I	1.289	0.99
341_T	351_R	1.284	0.99
133_G	136_V	1.279	0.99
397_L	401_F	1.278	0.99
388_V	398_T	1.275	0.99
410_A	413_L	1.274	0.99
387_L	394_T	1.272	0.99
218_V	222_V	1.269	0.99
409_I	416_I	1.260	0.99
57_V	64_V	1.256	0.99
396_L	400_V	1.254	0.99
358_G	364_P	1.248	0.99
362_I	365_A	1.245	0.99
216_G	219_V	1.241	0.99
197_S	202_L	1.239	0.99
489_T	498_V	1.235	0.99
370_L	378_Y	1.232	0.99
357_V	361_G	1.230	0.99
77_A	304_G	1.225	0.99
383_A	402_E	1.225	0.99
537_A	541_G	1.216	0.99
354_M	362_I	1.215	0.99
354_M	357_V	1.214	0.99
279_D	457_R	1.211	0.99
205_F	208_R	1.210	0.99
88_V	146_A	1.210	0.99
225_Y	229_R	1.204	0.99
387_L	402_E	1.204	0.99
361_G	366_S	1.197	0.99
204_D	208_R	1.192	0.99
354_M	363_I	1.192	0.99
523_A	526_D	1.192	0.99
422_I	432_L	1.186	0.99
408_H	411_Q	1.185	0.99
118_A	122_T	1.182	0.99
286_I	289_F	1.180	0.99
447_E	452_A	1.176	0.99
449_D	452_A	1.170	0.99
143_L	368_A	1.169	0.99
423_V	498_V	1.168	0.99
349_A	353_F	1.165	0.98
287_E	291_G	1.164	0.98
385_N	399_V	1.157	0.98
165_V	350_E	1.156	0.98
40_D	43_Q	1.151	0.98
197_S	201_V	1.150	0.98
398_T	406_A	1.150	0.98
362_I	367_V	1.149	0.98
403_G	407_R	1.148	0.98
254_G	258_T	1.131	0.98
112_T	116_A	1.128	0.98
398_T	404_G	1.124	0.98
119_L	183_L	1.122	0.98
384_A	387_L	1.120	0.98
203_Q	206_V	1.119	0.98
122_T	126_V	1.118	0.98
359_P	368_A	1.110	0.98
197_S	200_V	1.108	0.98
407_R	410_A	1.098	0.98
400_V	404_G	1.096	0.98
410_A	415_V	1.090	0.98
396_L	403_G	1.085	0.98
401_F	405_F	1.080	0.98
225_Y	228_R	1.079	0.98
67_L	75_T	1.075	0.97
384_A	388_V	1.071	0.97
363_I	367_V	1.071	0.97
342_A	345_R	1.070	0.97
326_V	330_L	1.068	0.97
285_E	291_G	1.065	0.97
500_Q	504_S	1.061	0.97
400_V	403_G	1.058	0.97
396_L	402_E	1.056	0.97
479_A	505_K	1.053	0.97
359_P	367_V	1.051	0.97
389_G	406_A	1.051	0.97
52_L	56_V	1.050	0.97
315_L	319_V	1.050	0.97
215_V	219_V	1.049	0.97
327_L	331_V	1.049	0.97
411_Q	415_V	1.048	0.97
168_A	346_Y	1.047	0.97
486_T	546_I	1.047	0.97
368_A	371_F	1.033	0.97
212_G	220_A	1.018	0.96
110_L	340_S	1.015	0.96
126_V	132_T	1.015	0.96
407_R	413_L	1.015	0.96
390_T	393_L	1.009	0.96
125_V	129_L	1.009	0.96
385_N	395_I	1.006	0.96
180_A	367_V	1.005	0.96
116_A	120_F	1.005	0.96
447_E	453_V	1.002	0.96
132_T	137_A	1.001	0.96
354_M	359_P	1.001	0.96
517_N	520_N	1.000	0.96
320_A	324_V	1.000	0.96
146_A	183_L	0.998	0.96
393_L	402_E	0.998	0.96
496_L	527_L	0.997	0.96
392_F	402_E	0.997	0.96
45_P	154_P	0.989	0.96
388_V	393_L	0.982	0.96
342_A	348_S	0.980	0.96
56_V	61_V	0.979	0.96
453_V	463_V	0.979	0.96
471_T	505_K	0.979	0.96
515_A	521_I	0.978	0.96
234_K	451_E	0.977	0.96
496_L	523_A	0.975	0.95
393_L	406_A	0.969	0.95
55_I	61_V	0.963	0.95
211_T	215_V	0.962	0.95
212_G	216_G	0.961	0.95
422_I	486_T	0.960	0.95
383_A	398_T	0.960	0.95
224_W	278_A	0.955	0.95
69_S	77_A	0.955	0.95
399_V	404_G	0.953	0.95
516_N	534_S	0.953	0.95
357_V	373_V	0.949	0.95
111_V	114_G	0.948	0.95
118_A	337_V	0.944	0.95
26_A	254_G	0.937	0.94
357_V	368_A	0.936	0.94
383_A	394_T	0.935	0.94
384_A	391_V	0.923	0.94
389_G	405_F	0.922	0.94
198_V	201_V	0.922	0.94
426_G	429_G	0.921	0.94
329_A	360_R	0.920	0.94
425_G	433_A	0.920	0.94
364_P	367_V	0.919	0.94
468_G	498_V	0.918	0.94
391_V	396_L	0.917	0.94
362_I	373_V	0.916	0.94
456_A	461_Y	0.913	0.94
423_V	468_G	0.913	0.94
390_T	396_L	0.912	0.94
498_V	502_A	0.910	0.93
147_T	176_N	0.907	0.93
385_N	388_V	0.904	0.93
479_A	509_D	0.902	0.93
106_A	171_T	0.902	0.93
392_F	396_L	0.899	0.93
388_V	394_T	0.898	0.93
478_G	481_N	0.898	0.93
118_A	176_N	0.896	0.93
227_L	248_G	0.895	0.93
475_R	505_K	0.894	0.93
253_Y	264_G	0.894	0.93
452_A	455_R	0.887	0.93
199_D	202_L	0.885	0.93
115_A	179_T	0.885	0.93
492_D	495_N	0.883	0.92
390_T	406_A	0.883	0.92
108_L	112_T	0.882	0.92
361_G	365_A	0.881	0.92
285_E	288_A	0.878	0.92
210_G	214_L	0.876	0.92
183_L	367_V	0.870	0.92
359_P	370_L	0.867	0.92
359_P	365_A	0.865	0.92
356_A	360_R	0.863	0.92
114_G	118_A	0.861	0.91
139_L	143_L	0.861	0.91
522_D	526_D	0.860	0.91
489_T	495_N	0.854	0.91
386_V	391_V	0.847	0.91
326_V	393_L	0.845	0.91
28_I	36_Q	0.845	0.91
321_G	324_V	0.844	0.91
456_A	459_E	0.842	0.91
115_A	175_V	0.841	0.91
533_S	537_A	0.834	0.90
93_F	273_V	0.834	0.90
419_R	442_N	0.830	0.90
496_L	520_N	0.830	0.90
502_A	506_F	0.829	0.90
435_R	543_D	0.829	0.90
283_E	291_G	0.825	0.90
408_H	413_L	0.824	0.90
356_A	366_S	0.822	0.89
379_G	399_V	0.821	0.89
536_L	540_W	0.820	0.89
287_E	290_K	0.819	0.89
210_G	322_L	0.816	0.89
388_V	400_V	0.815	0.89
393_L	396_L	0.811	0.89
537_A	542_I	0.811	0.89
205_F	216_G	0.811	0.89
201_V	204_D	0.810	0.89
421_I	485_L	0.808	0.89
386_V	405_F	0.808	0.89
110_L	344_S	0.806	0.89
96_K	277_N	0.804	0.88
200_V	203_Q	0.803	0.88
363_I	371_F	0.796	0.88
541_G	545_I	0.795	0.88
361_G	364_P	0.791	0.88
392_F	406_A	0.790	0.88
156_L	166_G	0.789	0.87
408_H	416_I	0.789	0.87
387_L	403_G	0.787	0.87
251_V	255_A	0.786	0.87
285_E	470_D	0.786	0.87
172_E	354_M	0.785	0.87
487_A	513_A	0.783	0.87
211_T	219_V	0.781	0.87
123_A	128_V	0.781	0.87
410_A	414_N	0.779	0.87
540_W	547_E	0.778	0.87
495_N	527_L	0.778	0.87
304_G	308_L	0.770	0.86
169_L	305_L	0.769	0.86
213_V	217_L	0.768	0.86
203_Q	212_G	0.767	0.86
486_T	512_I	0.766	0.86
412_A	415_V	0.766	0.86
23_P	26_A	0.765	0.86
208_R	212_G	0.765	0.86
48_L	400_V	0.762	0.86
334_P	356_A	0.760	0.85
534_S	538_T	0.759	0.85
399_V	407_R	0.757	0.85
356_A	364_P	0.753	0.85
354_M	360_R	0.750	0.85
286_I	290_K	0.749	0.85
361_G	368_A	0.749	0.85
86_V	184_A	0.746	0.84
209_L	220_A	0.746	0.84
497_L	500_Q	0.745	0.84
420_V	436_L	0.744	0.84
387_L	392_F	0.744	0.84
132_T	140_I	0.743	0.84
363_I	373_V	0.740	0.84
512_I	546_I	0.740	0.84
446_V	464_H	0.740	0.84
356_A	405_F	0.739	0.84
362_I	371_F	0.738	0.84
115_A	118_A	0.737	0.84
44_V	51_I	0.737	0.84
518_P	533_S	0.735	0.84
152_I	357_V	0.735	0.84
95_L	276_G	0.734	0.83
141_G	145_V	0.733	0.83
384_A	405_F	0.733	0.83
152_I	173_G	0.731	0.83
202_L	205_F	0.729	0.83
341_T	346_Y	0.726	0.83
529_V	533_S	0.725	0.83
140_I	144_L	0.724	0.83
385_N	403_G	0.724	0.83
101_R	104_P	0.723	0.83
514_R	534_S	0.721	0.82
417_P	483_K	0.721	0.82
98_E	102_E	0.721	0.82
176_N	180_A	0.718	0.82
133_G	137_A	0.718	0.82
85_A	88_V	0.717	0.82
494_V	497_L	0.717	0.82
241_A	245_V	0.717	0.82
437_E	443_V	0.717	0.82
42_L	469_S	0.716	0.82
319_V	322_L	0.716	0.82
268_V	351_R	0.715	0.82
58_G	65_V	0.712	0.82
445_L	461_Y	0.711	0.81
490_G	534_S	0.711	0.81
230_I	244_V	0.710	0.81
408_H	414_N	0.709	0.81
512_I	542_I	0.708	0.81
55_I	396_L	0.707	0.81
143_L	183_L	0.706	0.81
104_P	540_W	0.704	0.81
363_I	370_L	0.704	0.81
223_V	248_G	0.704	0.81
244_V	248_G	0.704	0.81
543_D	547_E	0.703	0.81
384_A	389_G	0.702	0.81
353_F	360_R	0.702	0.81
196_R	199_D	0.699	0.80
120_F	123_A	0.699	0.80
385_N	402_E	0.698	0.80
389_G	400_V	0.696	0.80
230_I	241_A	0.696	0.80
360_R	365_A	0.695	0.80
387_L	406_A	0.692	0.80
386_V	406_A	0.692	0.80
433_A	443_V	0.692	0.80
391_V	397_L	0.692	0.80
126_V	130_L	0.691	0.80
123_A	126_V	0.690	0.79
425_G	445_L	0.690	0.79
173_G	176_N	0.689	0.79
394_T	404_G	0.689	0.79
407_R	415_V	0.687	0.79
50_L	299_S	0.686	0.79
317_L	321_G	0.684	0.79
198_V	203_Q	0.682	0.79
390_T	405_F	0.681	0.79
492_D	523_A	0.679	0.78
492_D	520_N	0.678	0.78
356_A	368_A	0.678	0.78
165_V	353_F	0.677	0.78
30_A	34_L	0.677	0.78
397_L	402_E	0.676	0.78
221_A	225_Y	0.675	0.78
36_Q	299_S	0.674	0.78
252_A	274_L	0.674	0.78
394_T	400_V	0.673	0.78
392_F	405_F	0.672	0.78
387_L	400_V	0.671	0.78
362_I	370_L	0.671	0.78
53_A	278_A	0.671	0.78
449_D	463_V	0.671	0.78
506_F	509_D	0.670	0.77
535_S	539_A	0.669	0.77
496_L	500_Q	0.669	0.77
429_G	488_A	0.667	0.77
453_V	465_S	0.667	0.77
317_L	386_V	0.666	0.77
471_T	501_L	0.666	0.77
532_V	541_G	0.665	0.77
358_G	371_F	0.663	0.77
181_A	265_I	0.662	0.77
420_V	441_E	0.661	0.77
353_F	368_A	0.661	0.77
94_H	150_T	0.661	0.77
345_R	348_S	0.661	0.77
26_A	250_L	0.660	0.76
339_A	343_R	0.659	0.76
150_T	173_G	0.658	0.76
347_T	351_R	0.657	0.76
385_N	394_T	0.656	0.76
273_V	285_E	0.656	0.76
452_A	456_A	0.655	0.76
55_I	210_G	0.655	0.76
172_E	337_V	0.653	0.76
420_V	486_T	0.653	0.76
484_I	510_T	0.653	0.76
286_I	291_G	0.652	0.76
390_T	400_V	0.650	0.75
206_V	209_L	0.648	0.75
134_W	137_A	0.648	0.75
427_T	490_G	0.648	0.75
151_V	445_L	0.646	0.75
359_P	373_V	0.645	0.75
148_G	301_V	0.644	0.75
510_T	531_T	0.641	0.74
331_V	334_P	0.641	0.74
26_A	33_V	0.641	0.74
27_T	31_L	0.641	0.74
385_N	398_T	0.640	0.74
535_S	538_T	0.640	0.74
409_I	414_N	0.640	0.74
386_V	393_L	0.639	0.74
386_V	400_V	0.639	0.74
388_V	406_A	0.639	0.74
102_E	105_G	0.639	0.74
197_S	204_D	0.639	0.74
312_Q	316_D	0.638	0.74
319_V	323_A	0.638	0.74
427_T	514_R	0.637	0.74
119_L	123_A	0.637	0.74
532_V	542_I	0.637	0.74
327_L	481_N	0.634	0.74
420_V	484_I	0.634	0.74
537_A	540_W	0.633	0.73
64_V	444_V	0.633	0.73
400_V	405_F	0.632	0.73
514_R	535_S	0.631	0.73
450_P	454_E	0.630	0.73
531_T	545_I	0.630	0.73
401_F	404_G	0.629	0.73
57_V	307_A	0.627	0.73
310_S	313_T	0.626	0.73
483_K	510_T	0.625	0.72
313_T	317_L	0.625	0.72
107_W	126_V	0.624	0.72
63_G	80_V	0.624	0.72
215_V	274_L	0.624	0.72
122_T	144_L	0.623	0.72
520_N	524_F	0.623	0.72
66_T	76_L	0.622	0.72
26_A	247_A	0.622	0.72
107_W	175_V	0.620	0.72
240_N	539_A	0.619	0.72
142_S	186_V	0.618	0.72
23_P	152_I	0.616	0.71
358_G	366_S	0.616	0.71
241_A	280_L	0.615	0.71
172_E	180_A	0.614	0.71
118_A	336_A	0.613	0.71
209_L	213_V	0.612	0.71
342_A	351_R	0.612	0.71
146_A	180_A	0.611	0.71
499_A	511_I	0.611	0.71
245_V	276_G	0.611	0.71
117_I	340_S	0.610	0.71
242_R	266_A	0.610	0.71
407_R	416_I	0.608	0.70
150_T	180_A	0.608	0.70
116_A	119_L	0.608	0.70
391_V	400_V	0.608	0.70
428_V	488_A	0.606	0.70
443_V	462_T	0.606	0.70
128_V	134_W	0.606	0.70
150_T	299_S	0.603	0.70
103_A	106_A	0.603	0.70
245_V	249_A	0.602	0.70
125_V	136_V	0.602	0.70
105_G	315_L	0.602	0.70
216_G	220_A	0.601	0.70
91_G	95_L	0.598	0.69
396_L	406_A	0.597	0.69
384_A	406_A	0.597	0.69
201_V	207_T	0.596	0.69
266_A	297_V	0.596	0.69
108_L	111_V	0.595	0.69
544_N	548_R	0.595	0.69
68_S	307_A	0.593	0.69
421_I	509_D	0.592	0.68
527_L	530_S	0.592	0.68
243_L	249_A	0.588	0.68
316_D	320_A	0.587	0.68
65_V	68_S	0.587	0.68
408_H	415_V	0.587	0.68
348_S	352_V	0.585	0.67
390_T	401_F	0.585	0.67
197_S	207_T	0.584	0.67
217_L	222_V	0.582	0.67
33_V	244_V	0.581	0.67
247_A	490_G	0.581	0.67
222_V	225_Y	0.579	0.67
61_V	64_V	0.578	0.67
239_Q	243_L	0.577	0.66
383_A	388_V	0.577	0.66
534_S	539_A	0.575	0.66
103_A	107_W	0.575	0.66
425_G	461_Y	0.574	0.66
113_V	340_S	0.574	0.66
446_V	477_A	0.574	0.66
387_L	393_L	0.574	0.66
95_L	307_A	0.573	0.66
112_T	175_V	0.572	0.66
391_V	405_F	0.571	0.66
92_A	306_A	0.570	0.65
384_A	393_L	0.570	0.65
389_G	408_H	0.570	0.65
542_I	546_I	0.570	0.65
319_V	324_V	0.570	0.65
163_D	195_Q	0.569	0.65
543_D	546_I	0.568	0.65
285_E	289_F	0.567	0.65
427_T	535_S	0.567	0.65
363_I	369_T	0.566	0.65
145_V	333_R	0.565	0.65
27_T	64_V	0.565	0.65
484_I	488_A	0.564	0.65
456_A	463_V	0.564	0.65
513_A	529_V	0.564	0.65
346_Y	349_A	0.563	0.65
120_F	198_V	0.563	0.65
239_Q	250_L	0.563	0.65
346_Y	351_R	0.562	0.64
52_L	69_S	0.562	0.64
434_E	459_E	0.562	0.64
121_G	124_I	0.561	0.64
358_G	361_G	0.560	0.64
362_I	372_A	0.560	0.64
333_R	357_V	0.560	0.64
209_L	216_G	0.560	0.64
212_G	274_L	0.560	0.64
368_A	373_V	0.560	0.64
346_Y	350_E	0.559	0.64
432_L	486_T	0.558	0.64
126_V	141_G	0.558	0.64
83_S	267_A	0.557	0.64
536_L	539_A	0.557	0.64
360_R	371_F	0.556	0.64
322_L	326_V	0.556	0.64
245_V	303_I	0.556	0.64
115_A	145_V	0.555	0.63
110_L	114_G	0.554	0.63
399_V	410_A	0.554	0.63
518_P	521_I	0.553	0.63
422_I	539_A	0.552	0.63
426_G	468_G	0.552	0.63
320_A	323_A	0.552	0.63
539_A	546_I	0.550	0.63
429_G	447_E	0.550	0.63
59_P	466_G	0.550	0.63
196_R	200_V	0.550	0.63
83_S	301_V	0.549	0.63
264_G	300_F	0.549	0.63
39_A	52_L	0.549	0.63
144_L	427_T	0.549	0.63
403_G	408_H	0.548	0.62
84_V	296_V	0.547	0.62
533_S	538_T	0.547	0.62
241_A	244_V	0.546	0.62
121_G	332_I	0.546	0.62
368_A	372_A	0.545	0.62
223_V	227_L	0.545	0.62
310_S	316_D	0.544	0.62
244_V	249_A	0.543	0.62
321_G	325_A	0.543	0.62
80_V	304_G	0.543	0.62
33_V	36_Q	0.543	0.62
115_A	183_L	0.543	0.62
226_I	509_D	0.543	0.62
86_V	100_L	0.542	0.62
243_L	297_V	0.541	0.61
362_I	369_T	0.541	0.61
383_A	405_F	0.540	0.61
147_T	150_T	0.538	0.61
247_A	513_A	0.538	0.61
144_L	329_A	0.537	0.61
139_L	187_V	0.537	0.61
124_I	493_D	0.536	0.61
389_G	396_L	0.536	0.61
511_I	529_V	0.535	0.61
340_S	344_S	0.535	0.61
52_L	548_R	0.535	0.61
132_T	325_A	0.535	0.61
538_T	541_G	0.534	0.60
206_V	213_V	0.534	0.60
50_L	58_G	0.533	0.60
39_A	49_F	0.532	0.60
114_G	363_I	0.532	0.60
211_T	220_A	0.531	0.60
151_V	298_L	0.531	0.60
322_L	386_V	0.531	0.60
111_V	115_A	0.531	0.60
433_A	445_L	0.530	0.60
485_L	498_V	0.530	0.60
397_L	440_G	0.529	0.60
455_R	459_E	0.529	0.60
529_V	542_I	0.526	0.59
27_T	57_V	0.525	0.59
337_V	340_S	0.525	0.59
301_V	306_A	0.525	0.59
255_A	259_L	0.524	0.59
213_V	220_A	0.524	0.59
113_V	116_A	0.524	0.59
480_E	508_I	0.524	0.59
114_G	173_G	0.524	0.59
176_N	301_V	0.524	0.59
533_S	539_A	0.524	0.59
404_G	408_H	0.522	0.59
46_S	107_W	0.522	0.59
503_D	529_V	0.522	0.59
59_P	307_A	0.521	0.59
357_V	365_A	0.521	0.59
361_G	367_V	0.520	0.58
444_V	469_S	0.519	0.58
81_G	149_P	0.519	0.58
193_N	213_V	0.518	0.58
212_G	445_L	0.517	0.58
325_A	390_T	0.517	0.58
107_W	114_G	0.516	0.58
24_V	88_V	0.516	0.58
392_F	401_F	0.516	0.58
149_P	173_G	0.514	0.58
541_G	544_N	0.514	0.58
122_T	329_A	0.513	0.57
207_T	215_V	0.512	0.57
21_I	24_V	0.512	0.57
83_S	269_A	0.511	0.57
366_S	370_L	0.511	0.57
267_A	301_V	0.511	0.57
32_G	223_V	0.510	0.57
513_A	527_L	0.509	0.57
180_A	184_A	0.509	0.57
137_A	467_D	0.509	0.57
284_K	287_E	0.508	0.57
512_I	531_T	0.507	0.57
213_V	218_V	0.507	0.57
359_P	402_E	0.507	0.57
214_L	217_L	0.506	0.56
365_A	371_F	0.506	0.56
360_R	367_V	0.506	0.56
468_G	489_T	0.505	0.56
190_V	331_V	0.505	0.56
145_V	176_N	0.503	0.56
124_I	134_W	0.503	0.56
263_A	269_A	0.503	0.56
114_G	176_N	0.502	0.56
243_L	296_V	0.502	0.56
39_A	178_V	0.501	0.56
280_L	465_S	0.500	0.56
34_L	38_V	0.500	0.56

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4bwzA	2	0.5965	100	0.643	Contact Map
4czbA	2	0.6122	100	0.655	Contact Map
4cz8A	2	0.6091	100	0.658	Contact Map
4gx0A	3	0.4819	100	0.749	Contact Map
1lnqA	6	0.4584	100	0.749	Contact Map
2aefA	2	0.3407	100	0.766	Contact Map
3l4bC	2	0.3344	100	0.787	Contact Map
3mt5A	5	0.3312	100	0.787	Contact Map
4g65A	2	0.3485	100	0.788	Contact Map
3nafA	3	0.3532	100	0.788	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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