GREMLIN Database
Q9HNK0 - Long-chain fatty-acid-CoA ligase
UniProt: Q9HNK0 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 650 (569)
Sequences: 6652 (4554)
Seq/√Len: 190.9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
471_P475_D4.3691.00
456_L493_V4.3531.00
433_E459_R4.1631.00
204_L221_A3.7121.00
587_Q591_D3.6671.00
470_L473_A3.6621.00
135_G469_G3.6321.00
137_V161_E3.5181.00
255_R373_E3.4281.00
223_T465_D3.2631.00
473_A476_A3.2511.00
424_T502_R3.2361.00
85_V113_G3.1351.00
405_L487_F3.0291.00
412_L458_A2.9561.00
254_S375_E2.9361.00
494_E502_R2.8511.00
478_F488_R2.8181.00
456_L501_V2.7791.00
128_A156_D2.7221.00
92_G136_A2.6961.00
437_D453_A2.6691.00
133_D209_Y2.6391.00
435_T457_L2.6361.00
89_D137_V2.5991.00
421_I498_D2.4821.00
95_A98_R2.4751.00
299_E373_E2.4591.00
202_D225_R2.4541.00
480_T488_R2.4491.00
495_L501_V2.4251.00
225_R461_P2.4191.00
221_A466_G2.3991.00
46_R50_P2.3671.00
53_V67_D2.3641.00
79_G179_V2.3611.00
572_D575_A2.3411.00
104_C140_V2.3071.00
477_A487_F2.2761.00
75_T184_R2.2601.00
636_A640_G2.2221.00
456_L503_F2.2071.00
626_K631_I2.1801.00
133_D470_L2.1781.00
432_T462_Q2.1741.00
457_L488_R2.1721.00
72_I180_Y2.1441.00
105_D268_R2.1411.00
458_A463_V2.1331.00
359_D367_R2.1251.00
226_N463_V2.1171.00
108_V113_G2.1061.00
73_V107_A2.0971.00
305_S310_Y2.0811.00
607_R642_V2.0511.00
76_L107_A2.0441.00
333_W358_A2.0311.00
91_V108_V2.0161.00
201_P225_R1.9821.00
408_T487_F1.9731.00
299_E372_G1.9671.00
133_D469_G1.9641.00
512_T518_N1.9581.00
55_P65_S1.9401.00
55_P63_T1.9321.00
200_D203_D1.9291.00
52_V67_D1.9101.00
453_A507_A1.8921.00
384_L389_C1.8831.00
379_S384_L1.8821.00
472_D476_A1.8771.00
48_L70_R1.8541.00
493_V501_V1.8521.00
586_I608_L1.8441.00
528_F537_A1.8311.00
580_E584_A1.8281.00
283_C298_F1.8211.00
181_D184_R1.8171.00
607_R638_A1.7831.00
67_D71_D1.7751.00
589_A592_D1.7731.00
70_R74_R1.7561.00
428_P434_L1.7501.00
325_P328_E1.7481.00
492_V505_E1.7331.00
58_D281_Q1.7281.00
221_A465_D1.7231.00
128_A132_G1.6871.00
68_A71_D1.6851.00
45_D70_R1.6801.00
114_A204_L1.6771.00
204_L465_D1.6681.00
140_V166_M1.6561.00
76_L176_L1.6411.00
58_D63_T1.6381.00
254_S301_T1.6141.00
421_I500_Y1.6141.00
413_A501_V1.6071.00
226_N409_S1.6051.00
408_T458_A1.6041.00
627_K630_H1.6011.00
310_Y377_F1.5941.00
632_R639_V1.5871.00
206_S268_R1.5791.00
47_S51_E1.5781.00
567_I579_D1.5651.00
316_T320_Q1.5621.00
619_L634_R1.5591.00
81_R111_A1.5591.00
531_S589_A1.5551.00
85_V138_G1.5491.00
191_A194_G1.5471.00
540_V548_S1.5381.00
76_L103_Q1.5371.00
607_R641_D1.5341.00
138_G162_F1.5321.00
343_T390_A1.5321.00
529_A537_A1.5291.00
475_D481_R1.5211.00
638_A641_D1.5201.00
537_A551_L1.4981.00
587_Q606_F1.4971.00
458_A489_T1.4961.00
75_T180_Y1.4931.00
204_L223_T1.4901.00
619_L630_H1.4871.00
129_H216_T1.4831.00
59_G99_M1.4811.00
324_S328_E1.4631.00
464_F477_A1.4611.00
64_L69_L1.4501.00
138_G164_A1.4451.00
95_A166_M1.4431.00
496_R500_Y1.4391.00
535_A612_E1.4381.00
535_A554_N1.4381.00
386_P390_A1.4351.00
630_H633_D1.4311.00
76_L140_V1.4281.00
175_P178_A1.4271.00
421_I496_R1.4241.00
223_T226_N1.4211.00
124_P152_E1.4111.00
64_L72_I1.4051.00
551_L606_F1.3931.00
544_Q640_G1.3791.00
96_H142_E1.3731.00
548_S642_V1.3731.00
56_A69_L1.3721.00
561_W565_Q1.3711.00
85_V91_V1.3531.00
434_L495_L1.3491.00
436_V456_L1.3461.00
74_R193_Q1.3401.00
65_S68_A1.3391.00
584_A588_S1.3371.00
416_P427_P1.3341.00
581_R584_A1.3281.00
509_Q522_G1.3281.00
586_I589_A1.3221.00
98_R167_D1.3131.00
178_A181_D1.3121.00
437_D457_L1.3111.00
255_R281_Q1.3051.00
92_G131_L1.3011.00
80_F108_V1.3001.00
139_V150_V1.2881.00
322_A328_E1.2811.00
328_E332_E1.2741.00
527_A596_G1.2731.00
82_D182_R1.2721.00
54_D253_D1.2701.00
109_L205_A1.2691.00
434_L458_A1.2661.00
433_E486_W1.2661.00
76_L179_V1.2631.00
550_I609_V1.2631.00
496_R502_R1.2611.00
86_T89_D1.2581.00
38_A42_G1.2561.00
71_D75_T1.2561.00
81_R195_W1.2451.00
419_D427_P1.2441.00
437_D454_G1.2421.00
275_P280_A1.2341.00
181_D185_D1.2311.00
69_L106_L1.2311.00
464_F478_F1.2301.00
290_T293_E1.2271.00
611_T617_N1.2251.00
460_G463_V1.2241.00
314_Y318_R1.2241.00
633_D636_A1.2171.00
629_H633_D1.2171.00
176_L180_Y1.2161.00
134_S209_Y1.2151.00
91_V113_G1.2141.00
221_A468_W1.2141.00
90_R468_W1.2131.00
105_D206_S1.2101.00
222_L226_N1.2071.00
301_T373_E1.2051.00
108_V115_V1.2021.00
558_V582_V1.2011.00
528_F534_V1.1981.00
102_A284_Y1.1971.00
481_R488_R1.1951.00
457_L480_T1.1931.00
72_I103_Q1.1891.00
434_L456_L1.1871.00
107_A111_A1.1841.00
478_F487_F1.1821.00
255_R301_T1.1821.00
555_F559_S1.1811.00
436_V495_L1.1801.00
44_Y48_L1.1791.00
99_M103_Q1.1771.00
565_Q581_R1.1751.00
360_T364_S1.1741.00
258_S267_E1.1691.00
253_D301_T1.1601.00
144_D148_Q1.1541.00
437_D488_R1.1531.00
146_L149_R1.1471.00
129_H133_D1.1421.00
235_R278_S1.1411.00
551_L590_V1.1371.00
401_E423_G1.1351.00
434_L501_V1.1331.00
77_A111_A1.1291.00
538_M626_K1.1281.00
405_L408_T1.1241.00
408_T463_V1.1231.00
90_R116_T1.1221.00
64_L99_M1.1211.00
380_G402_G1.1181.00
434_L493_V1.1161.00
131_L136_A1.1161.00
336_R340_A1.1081.00
551_L586_I1.1081.00
98_R142_E1.1031.00
77_A110_A1.0961.00
492_V507_A1.0951.00
51_E54_D1.0901.00
135_G159_D1.0901.00
641_D644_D1.0881.00
296_G369_A1.0871.00
599_P602_R1.0861.00
236_R430_T1.0861.00
285_A294_D1.0801.00
74_R110_A1.0781.00
637_D641_D1.0761.00
87_A203_D1.0761.00
614_T617_N1.0751.00
314_Y388_L1.0701.00
611_T619_L1.0701.00
44_Y73_V1.0681.00
56_A66_Y1.0681.00
324_S327_S1.0671.00
80_F140_V1.0641.00
549_A603_I1.0601.00
182_R185_D1.0581.00
72_I75_T1.0521.00
585_R588_S1.0471.00
571_D575_A1.0451.00
567_I581_R1.0431.00
93_V115_V1.0431.00
202_D465_D1.0401.00
46_R49_A1.0391.00
76_L80_F1.0381.00
474_T478_F1.0361.00
230_N462_Q1.0341.00
562_A567_I1.0331.00
538_M632_R1.0311.00
329_R333_W1.0291.00
419_D500_Y1.0281.00
390_A422_V1.0261.00
413_A434_L1.0261.00
561_W582_V1.0261.00
437_D507_A1.0251.00
55_P58_D1.0241.00
528_F603_I1.0231.00
54_D252_S1.0211.00
339_R343_T1.0211.00
112_G199_R1.0201.00
69_L103_Q1.0171.00
580_E583_R1.0111.00
349_I352_R1.0111.00
333_W336_R1.0061.00
94_F127_I1.0061.00
177_S181_D1.0051.00
266_L304_T1.0031.00
533_L585_R1.0031.00
92_G139_V0.9991.00
383_S543_G0.9950.99
577_C608_L0.9940.99
287_S290_T0.9920.99
428_P499_G0.9920.99
266_L402_G0.9880.99
131_L157_L0.9860.99
139_V160_L0.9860.99
266_L378_I0.9850.99
333_W337_V0.9850.99
456_L495_L0.9800.99
605_Q642_V0.9740.99
220_V464_F0.9720.99
58_D283_C0.9690.99
340_A354_A0.9690.99
147_R151_R0.9660.99
294_D297_L0.9640.99
508_K518_N0.9620.99
207_L468_W0.9610.99
105_D115_V0.9610.99
258_S282_V0.9590.99
466_G471_P0.9580.99
233_Q431_D0.9570.99
320_Q323_D0.9570.99
459_R486_W0.9560.99
540_V639_V0.9540.99
193_Q197_D0.9490.99
125_A596_G0.9490.99
230_N411_V0.9480.99
635_F638_A0.9470.99
199_R224_H0.9440.99
361_L365_D0.9440.99
230_N410_P0.9380.99
118_V127_I0.9370.99
81_R192_Y0.9350.99
45_D49_A0.9350.99
478_F481_R0.9340.99
415_N500_Y0.9330.99
229_A461_P0.9320.99
141_V147_R0.9310.99
76_L104_C0.9310.99
598_E601_E0.9260.99
199_R203_D0.9230.99
229_A462_Q0.9230.99
47_S279_G0.9210.99
251_T254_S0.9190.99
364_S367_R0.9170.99
97_T258_S0.9170.99
132_G157_L0.9170.99
295_F303_A0.9110.99
560_E564_S0.9040.99
195_W198_D0.9030.99
339_R390_A0.9030.99
579_D582_V0.9030.99
552_V609_V0.9020.99
226_N465_D0.9010.99
168_T177_S0.9010.99
524_I597_F0.8980.99
321_A331_F0.8960.99
83_L182_R0.8960.99
320_Q369_A0.8950.99
60_G297_L0.8940.99
286_E294_D0.8900.99
64_L103_Q0.8870.99
61_V297_L0.8860.99
455_E488_R0.8800.99
436_V493_V0.8790.99
588_S592_D0.8790.99
325_P329_R0.8780.99
72_I99_M0.8780.99
552_V613_F0.8750.99
436_V501_V0.8740.99
585_R589_A0.8720.99
177_S180_Y0.8710.99
57_P69_L0.8700.99
536_Q552_V0.8700.99
314_Y391_L0.8680.99
63_T281_Q0.8640.99
640_G644_D0.8620.99
50_P279_G0.8600.99
73_V110_A0.8600.99
83_L162_F0.8580.98
87_A112_G0.8570.98
368_D372_G0.8570.98
546_F642_V0.8570.98
594_N603_I0.8540.98
583_R587_Q0.8530.98
132_G159_D0.8520.98
209_Y219_G0.8520.98
129_H470_L0.8510.98
190_D194_G0.8500.98
327_S330_V0.8450.98
92_G118_V0.8430.98
255_R283_C0.8420.98
303_A374_I0.8400.98
290_T294_D0.8400.98
90_R135_G0.8380.98
191_A195_W0.8370.98
578_R583_R0.8350.98
68_A72_I0.8330.98
347_P351_L0.8320.98
509_Q626_K0.8320.98
427_P500_Y0.8320.98
211_S625_K0.8310.98
350_G354_A0.8280.98
333_W354_A0.8260.98
63_T298_F0.8250.98
352_R356_A0.8240.98
557_A560_E0.8240.98
90_R114_A0.8230.98
231_L277_A0.8220.98
106_L276_L0.8220.98
227_F409_S0.8180.98
538_M631_I0.8170.98
132_G158_D0.8150.98
229_A431_D0.8150.98
524_I603_I0.8110.98
86_T137_V0.8100.98
590_V593_V0.8090.98
47_S66_Y0.8080.98
570_P575_A0.8080.98
402_G410_P0.8080.98
301_T375_E0.8070.98
269_L410_P0.8060.98
86_T195_W0.8010.98
523_P601_E0.8000.98
77_A107_A0.7990.98
338_G342_H0.7960.98
355_H363_F0.7950.98
39_Y199_R0.7940.97
292_R296_G0.7940.97
331_F335_T0.7940.97
357_L361_L0.7940.97
587_Q590_V0.7930.97
132_G216_T0.7930.97
70_R110_A0.7920.97
57_P99_M0.7890.97
194_G197_D0.7890.97
415_N424_T0.7880.97
165_T169_P0.7880.97
337_V351_L0.7880.97
267_E271_G0.7880.97
538_M613_F0.7860.97
133_D468_W0.7860.97
55_P281_Q0.7850.97
511_L518_N0.7850.97
266_L410_P0.7850.97
296_G368_D0.7840.97
334_A358_A0.7840.97
271_G284_Y0.7810.97
416_P500_Y0.7800.97
190_D193_Q0.7800.97
603_I606_F0.7790.97
337_V354_A0.7770.97
293_E296_G0.7770.97
334_A362_V0.7740.97
349_I353_A0.7740.97
104_C176_L0.7720.97
531_S534_V0.7710.97
412_L434_L0.7690.97
266_L381_G0.7680.97
609_V635_F0.7680.97
101_W262_L0.7680.97
589_A593_V0.7680.97
330_V362_V0.7670.97
119_Y263_A0.7660.97
471_P474_T0.7650.97
546_F604_K0.7620.97
207_L219_G0.7600.97
617_N634_R0.7600.97
204_L466_G0.7580.97
143_N167_D0.7570.97
562_A576_I0.7570.97
472_D475_D0.7550.97
488_R507_A0.7530.97
335_T394_G0.7530.97
147_R165_T0.7530.97
550_I607_R0.7520.97
618_D630_H0.7520.97
38_A201_P0.7500.96
621_T627_K0.7500.96
72_I176_L0.7490.96
48_L52_V0.7470.96
74_R196_I0.7470.96
80_F138_G0.7470.96
358_A363_F0.7420.96
74_R192_Y0.7410.96
205_A227_F0.7410.96
584_A587_Q0.7400.96
326_V329_R0.7380.96
45_D110_A0.7360.96
505_E629_H0.7340.96
75_T183_G0.7340.96
212_G506_R0.7340.96
536_Q620_L0.7330.96
559_S563_A0.7310.96
211_S506_R0.7310.96
611_T634_R0.7300.96
326_V330_V0.7280.96
83_L164_A0.7260.96
558_V562_A0.7250.96
611_T635_F0.7240.96
79_G183_G0.7220.96
56_A276_L0.7200.96
78_A193_Q0.7190.96
553_P558_V0.7190.96
431_D462_Q0.7180.95
463_V487_F0.7170.95
575_A578_R0.7160.95
617_N620_L0.7140.95
389_C401_E0.7140.95
39_Y201_P0.7130.95
513_L519_V0.7130.95
561_W564_S0.7090.95
575_A579_D0.7090.95
310_Y399_I0.7090.95
511_L541_G0.7080.95
125_A128_A0.7070.95
539_V549_A0.7060.95
250_V254_S0.7050.95
592_D595_T0.7040.95
95_A101_W0.7020.95
614_T618_D0.7000.95
256_H275_P0.7000.95
637_D640_G0.6980.95
519_V547_V0.6970.95
95_A142_E0.6960.95
524_I593_V0.6920.94
227_F273_F0.6910.94
478_F486_W0.6880.94
59_G62_E0.6880.94
493_V503_F0.6870.94
109_L273_F0.6860.94
45_D74_R0.6860.94
45_D197_D0.6860.94
424_T496_R0.6850.94
505_E522_G0.6840.94
225_R465_D0.6840.94
514_S545_K0.6840.94
337_V340_A0.6830.94
582_V586_I0.6830.94
85_V111_A0.6820.94
64_L68_A0.6810.94
131_L139_V0.6790.94
93_V101_W0.6780.94
381_G623_T0.6780.94
222_L409_S0.6780.94
364_S368_D0.6780.94
125_A216_T0.6780.94
85_V137_V0.6780.94
388_L392_F0.6750.94
583_R607_R0.6750.94
436_V504_L0.6750.94
178_A182_R0.6750.94
405_L477_A0.6750.94
255_R298_F0.6740.94
205_A224_H0.6730.94
132_G156_D0.6720.94
57_P103_Q0.6720.94
561_W566_E0.6690.93
533_L589_A0.6670.93
52_V65_S0.6660.93
553_P586_I0.6660.93
590_V603_I0.6650.93
531_S585_R0.6650.93
515_T518_N0.6640.93
90_R469_G0.6640.93
42_G46_R0.6640.93
318_R332_E0.6620.93
102_A271_G0.6620.93
534_V589_A0.6620.93
493_V504_L0.6620.93
71_D184_R0.6620.93
193_Q196_I0.6600.93
577_C610_A0.6600.93
583_R608_L0.6600.93
353_A357_L0.6600.93
51_E279_G0.6570.93
534_V551_L0.6560.93
311_E388_L0.6560.93
579_D583_R0.6560.93
286_E290_T0.6550.93
457_L478_F0.6540.93
573_R577_C0.6520.93
115_V268_R0.6520.93
348_G351_L0.6480.92
94_F120_A0.6480.92
591_D606_F0.6470.92
157_L160_L0.6470.92
79_G83_L0.6460.92
367_R397_L0.6450.92
393_H420_P0.6450.92
560_E563_A0.6440.92
583_R605_Q0.6440.92
553_P608_L0.6430.92
412_L462_Q0.6430.92
251_T375_E0.6420.92
104_C166_M0.6410.92
305_S309_V0.6400.92
114_A207_L0.6390.92
316_T319_E0.6380.92
365_D368_D0.6380.92
265_V410_P0.6370.92
353_A356_A0.6360.92
200_D225_R0.6360.92
135_G468_W0.6350.92
293_E297_L0.6330.91
537_A549_A0.6330.91
383_S386_P0.6330.91
424_T500_Y0.6320.91
377_F397_L0.6320.91
93_V104_C0.6310.91
87_A197_D0.6310.91
525_E628_R0.6310.91
413_A458_A0.6310.91
78_A192_Y0.6310.91
556_D559_S0.6310.91
259_F305_S0.6290.91
94_F149_R0.6290.91
129_H132_G0.6290.91
232_N277_A0.6290.91
235_R274_L0.6280.91
559_S573_R0.6280.91
69_L276_L0.6270.91
412_L432_T0.6270.91
351_L355_H0.6260.91
400_L417_Y0.6260.91
361_L364_S0.6260.91
421_I424_T0.6260.91
87_A200_D0.6230.91
230_N409_S0.6230.91
539_V547_V0.6230.91
574_D578_R0.6220.91
130_L219_G0.6210.91
61_V283_C0.6200.91
511_L521_P0.6200.91
310_Y379_S0.6200.91
63_T283_C0.6190.91
148_Q152_E0.6190.91
211_S264_H0.6190.91
562_A566_E0.6180.90
453_A492_V0.6180.90
528_F593_V0.6180.90
425_I456_L0.6180.90
208_I265_V0.6170.90
59_G100_E0.6170.90
359_D364_S0.6150.90
512_T547_V0.6130.90
234_S429_V0.6130.90
225_R229_A0.6130.90
61_V298_F0.6130.90
150_V153_V0.6100.90
583_R586_I0.6100.90
88_G203_D0.6090.90
41_G45_D0.6090.90
59_G64_L0.6080.90
630_H634_R0.6070.90
168_T175_P0.6070.90
230_N269_L0.6070.90
85_V89_D0.6060.90
154_E158_D0.6060.90
89_D113_G0.6060.90
613_F626_K0.6030.89
287_S294_D0.6030.89
457_L507_A0.6010.89
71_D74_R0.6000.89
400_L416_P0.6000.89
546_F605_Q0.5990.89
356_A360_T0.5990.89
318_R321_A0.5990.89
291_L309_V0.5990.89
510_L518_N0.5970.89
94_F139_V0.5970.89
229_A233_Q0.5970.89
129_H217_P0.5930.89
206_S227_F0.5930.89
103_Q176_L0.5930.89
201_P224_H0.5930.89
355_H359_D0.5920.88
154_E160_L0.5920.88
148_Q151_R0.5910.88
124_P149_R0.5900.88
96_H120_A0.5900.88
611_T614_T0.5890.88
436_V454_G0.5870.88
318_R322_A0.5870.88
72_I100_E0.5860.88
226_N464_F0.5860.88
567_I571_D0.5850.88
73_V77_A0.5840.88
38_A46_R0.5840.88
555_F573_R0.5830.88
81_R86_T0.5820.88
251_T301_T0.5820.88
614_T619_L0.5820.88
104_C108_V0.5820.88
45_D196_I0.5810.88
143_N146_L0.5800.87
505_E520_A0.5800.87
88_G112_G0.5800.87
160_L163_V0.5800.87
192_Y195_W0.5800.87
85_V108_V0.5800.87
350_G353_A0.5770.87
424_T494_E0.5770.87
571_D576_I0.5770.87
261_P264_H0.5770.87
288_P292_R0.5760.87
153_V156_D0.5760.87
292_R316_T0.5750.87
210_T506_R0.5750.87
454_G492_V0.5740.87
227_F265_V0.5740.87
552_V612_E0.5730.87
158_D161_E0.5730.87
527_A597_F0.5710.87
40_K224_H0.5710.87
80_F104_C0.5710.87
324_S331_F0.5710.87
619_L635_F0.5700.87
81_R191_A0.5690.86
201_P232_N0.5680.86
177_S184_R0.5680.86
120_A263_A0.5680.86
474_T486_W0.5680.86
435_T486_W0.5670.86
162_F174_R0.5660.86
105_D109_L0.5660.86
229_A232_N0.5650.86
577_C586_I0.5650.86
69_L73_V0.5640.86
527_A530_A0.5610.86
258_S271_G0.5610.86
218_K625_K0.5590.86
524_I547_V0.5590.86
98_R166_M0.5580.85
270_S304_T0.5580.85
588_S591_D0.5580.85
79_G180_Y0.5580.85
308_R312_K0.5580.85
425_I501_V0.5570.85
54_D279_G0.5560.85
259_F303_A0.5560.85
91_V140_V0.5550.85
113_G138_G0.5550.85
319_E323_D0.5550.85
597_F600_Y0.5550.85
335_T338_G0.5540.85
382_G543_G0.5540.85
526_D529_A0.5530.85
79_G82_D0.5530.85
211_S214_T0.5530.85
329_R332_E0.5520.85
506_R625_K0.5520.85
562_A565_Q0.5520.85
106_L273_F0.5520.85
338_G363_F0.5520.85
108_V111_A0.5500.85
505_E509_Q0.5500.85
633_D637_D0.5500.85
509_Q538_M0.5500.85
391_L395_M0.5480.84
87_A198_D0.5480.84
544_Q643_Y0.5460.84
524_I539_V0.5460.84
341_A347_P0.5460.84
632_R636_A0.5460.84
393_H422_V0.5450.84
192_Y196_I0.5440.84
510_L520_A0.5440.84
466_G487_F0.5440.84
256_H280_A0.5420.84
474_T477_A0.5420.84
212_G218_K0.5420.84
174_R178_A0.5400.84
230_N412_L0.5390.83
428_P495_L0.5380.83
232_N236_R0.5380.83
574_D610_A0.5370.83
511_L543_G0.5370.83
49_A53_V0.5370.83
435_T482_E0.5370.83
356_A359_D0.5360.83
413_A428_P0.5350.83
381_G401_E0.5350.83
41_G110_A0.5350.83
207_L221_A0.5330.83
115_V206_S0.5320.83
470_L474_T0.5320.83
211_S218_K0.5310.82
118_V130_L0.5310.82
401_E415_N0.5300.82
400_L414_V0.5300.82
621_T625_K0.5290.82
131_L134_S0.5280.82
74_R78_A0.5270.82
165_T168_T0.5270.82
180_Y183_G0.5270.82
558_V564_S0.5270.82
105_D208_I0.5260.82
453_A517_K0.5260.82
533_L561_W0.5260.82
154_E157_L0.5250.82
117_T207_L0.5240.82
48_L66_Y0.5240.82
338_G355_H0.5230.82
133_D219_G0.5220.81
331_F338_G0.5220.81
302_S376_F0.5210.81
618_D627_K0.5210.81
412_L489_T0.5210.81
398_P418_E0.5200.81
233_Q429_V0.5200.81
49_A193_Q0.5190.81
455_E507_A0.5190.81
123_S126_Q0.5180.81
300_P307_P0.5180.81
337_V341_A0.5170.81
264_H517_K0.5160.81
405_L489_T0.5160.81
302_S375_E0.5150.81
491_D506_R0.5150.81
334_A363_F0.5150.81
366_I371_G0.5150.81
420_P500_Y0.5140.80
275_P282_V0.5130.80
473_A477_A0.5130.80
570_P579_D0.5120.80
421_I502_R0.5120.80
545_K548_S0.5120.80
347_P352_R0.5120.80
58_D61_V0.5120.80
480_T486_W0.5110.80
534_V537_A0.5110.80
618_D633_D0.5100.80
325_P330_V0.5100.80
563_A566_E0.5100.80
110_A192_Y0.5090.80
347_P350_G0.5090.80
370_L374_I0.5080.80
374_I377_F0.5080.80
517_K601_E0.5080.80
109_L115_V0.5080.80
256_H267_E0.5080.80
44_Y69_L0.5070.80
544_Q639_V0.5070.80
453_A494_E0.5070.80
257_L298_F0.5060.79
555_F558_V0.5060.79
429_V432_T0.5050.79
408_T412_L0.5050.79
409_S463_V0.5040.79
518_N547_V0.5040.79
94_F146_L0.5040.79
155_S158_D0.5040.79
357_L360_T0.5030.79
365_D371_G0.5020.79
76_L108_V0.5020.79
438_E453_A0.5010.79
92_G134_S0.5000.79
494_E497_P0.5000.79
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3tsyA 2 0.66 100 0.375 Contact Map
1mdbA 1 0.8 100 0.39 Contact Map
3ni2A 1 0.7892 100 0.393 Contact Map
2d1sA 1 0.8046 100 0.393 Contact Map
3etcA 2 0.7862 100 0.396 Contact Map
1v25A 2 0.7385 100 0.396 Contact Map
1amuA 1 0.7585 100 0.396 Contact Map
1ry2A 1 0.8231 100 0.4 Contact Map
2v7bA 1 0.7385 100 0.401 Contact Map
3rixA 1 0.64 100 0.401 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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