GREMLIN Database
Q9HNI7 - Possible phosphate binding protein
UniProt: Q9HNI7 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 320 (271)
Sequences: 3248 (2475)
Seq/√Len: 150.4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
192_A205_A4.4511.00
55_A59_D3.8411.00
109_D267_R3.7561.00
140_L204_A3.7031.00
36_D70_E3.1591.00
40_V89_A3.0281.00
146_V202_Y2.9201.00
128_T243_Q2.7651.00
264_G268_S2.7241.00
300_T303_D2.6381.00
135_D243_Q2.5561.00
272_T276_D2.5001.00
196_L205_A2.4721.00
268_S272_T2.4061.00
305_E308_R2.3971.00
64_E276_D2.3801.00
133_P243_Q2.3021.00
305_E309_N2.2931.00
99_A301_I2.2841.00
38_R70_E2.2801.00
129_Q200_D2.2331.00
301_I308_R2.2141.00
38_R90_D2.1741.00
123_F247_A2.1481.00
271_Q298_E2.1021.00
128_T132_S2.0771.00
147_F185_W2.0731.00
36_D68_S2.0671.00
169_D179_T2.0251.00
195_Q202_Y1.9971.00
135_D139_D1.9661.00
299_A303_D1.9311.00
111_V258_A1.8701.00
36_D67_A1.8001.00
121_R250_P1.7901.00
136_S139_D1.7651.00
145_V206_G1.7641.00
55_A58_F1.7611.00
144_T203_M1.7551.00
143_E203_M1.7251.00
126_I206_G1.7161.00
60_Y64_E1.7131.00
184_K202_Y1.6951.00
156_S185_W1.6911.00
59_D62_E1.6911.00
123_F209_A1.6891.00
21_L24_C1.6841.00
302_D305_E1.6751.00
148_G155_G1.6741.00
37_V91_I1.6471.00
161_Q165_D1.6421.00
65_T69_I1.6251.00
263_E266_V1.6151.00
87_D261_S1.6111.00
268_S271_Q1.6071.00
115_V295_G1.6011.00
162_M246_A1.5771.00
85_E106_S1.5501.00
103_D301_I1.5481.00
301_I305_E1.5331.00
127_T196_L1.5201.00
130_P243_Q1.5171.00
258_A267_R1.5001.00
84_L94_A1.4821.00
131_D243_Q1.4661.00
156_S160_L1.4651.00
144_T182_T1.4581.00
91_I270_V1.4211.00
238_E241_E1.4121.00
280_S283_K1.3911.00
94_A257_L1.3871.00
95_S153_T1.3581.00
186_S192_A1.3561.00
145_V181_F1.3551.00
115_V297_A1.3551.00
60_Y277_A1.3491.00
282_L286_N1.3431.00
76_D79_A1.3391.00
138_S166_A1.3151.00
18_I21_L1.3141.00
38_R72_K1.3131.00
81_L102_G1.3051.00
59_D63_S1.3021.00
113_I299_A1.2811.00
126_I204_A1.2801.00
83_A89_A1.2581.00
145_V204_A1.2481.00
13_A16_I1.2451.00
82_Q85_E1.2341.00
99_A103_D1.2311.00
62_E68_S1.2261.00
275_L298_E1.2221.00
40_V80_V1.2211.00
146_V186_S1.2131.00
165_D309_N1.2101.00
193_I207_T1.2021.00
266_V270_V1.1981.00
150_R185_W1.1821.00
281_D284_G1.1731.00
168_L180_D1.1631.00
128_T245_L1.1621.00
97_T311_K1.1551.00
193_I215_H1.1551.00
91_I262_W1.1471.00
57_V277_A1.1371.00
99_A255_P1.1371.00
158_F251_I1.1361.00
122_Y154_S1.1301.00
61_L65_T1.1180.99
193_I205_A1.0940.99
65_T266_V1.0900.99
158_F310_V1.0840.99
244_L247_A1.0800.99
123_F250_P1.0770.99
148_G185_W1.0750.99
266_V269_D1.0740.99
141_A168_L1.0690.99
107_V260_R1.0650.99
147_F183_G1.0590.99
12_A15_T1.0500.99
60_Y273_A1.0500.99
126_I140_L1.0450.99
67_A266_V1.0450.99
110_V299_A1.0410.99
91_I258_A1.0340.99
65_T273_A1.0310.99
153_T158_F1.0280.99
64_E273_A1.0230.99
126_I145_V1.0210.99
34_D67_A1.0200.99
146_V195_Q1.0160.99
37_V69_I1.0150.99
265_S268_S1.0100.99
14_G17_G1.0040.99
134_I143_E0.9980.99
19_S22_S0.9950.99
159_P206_G0.9930.99
39_F58_F0.9830.99
103_D308_R0.9780.99
161_Q310_V0.9730.99
259_R262_W0.9720.99
155_G189_H0.9700.98
208_G254_A0.9700.98
144_T184_K0.9650.98
271_Q275_L0.9650.98
39_F93_D0.9630.98
15_T18_I0.9580.98
162_M166_A0.9570.98
87_D259_R0.9540.98
278_T295_G0.9520.98
194_E199_R0.9510.98
58_F274_L0.9510.98
17_G20_G0.9490.98
124_S248_S0.9490.98
11_G17_G0.9470.98
193_I196_L0.9440.98
283_K286_N0.9430.98
90_D259_R0.9410.98
87_D90_D0.9410.98
20_G24_C0.9370.98
122_Y152_S0.9350.98
17_G21_L0.9330.98
81_L98_L0.9320.98
43_P77_H0.9320.98
127_T207_T0.9270.98
112_G275_L0.9250.98
133_P143_E0.9120.98
258_A262_W0.9120.98
99_A304_Y0.9020.98
79_A83_A0.9010.98
196_L242_L0.8830.97
97_T157_L0.8830.97
270_V274_L0.8790.97
12_A17_G0.8770.97
152_S189_H0.8740.97
129_Q203_M0.8730.97
170_V178_V0.8720.97
85_E105_A0.8710.97
168_L181_F0.8700.97
248_S251_I0.8620.97
95_S98_L0.8580.97
191_T194_E0.8540.97
125_T209_A0.8540.97
80_V89_A0.8520.97
164_A169_D0.8520.97
196_L202_Y0.8510.97
111_V256_L0.8500.97
100_V308_R0.8430.96
154_S208_G0.8420.96
77_H189_H0.8370.96
129_Q241_E0.8360.96
285_S289_D0.8350.96
265_S269_D0.8350.96
58_F62_E0.8240.96
132_S135_D0.8230.96
58_F71_P0.8220.96
252_P306_P0.8200.96
35_A67_A0.8170.96
37_V65_T0.8140.96
132_S243_Q0.8130.96
42_T98_L0.8100.95
16_I19_S0.8080.95
288_S291_L0.8060.95
74_A83_A0.8060.95
149_A152_S0.8040.95
144_T202_Y0.8000.95
11_G15_T0.7980.95
109_D260_R0.7960.95
19_S24_C0.7950.95
279_E282_L0.7910.95
162_M165_D0.7850.95
282_L285_S0.7840.95
281_D285_S0.7830.95
82_Q86_N0.7820.94
186_S195_Q0.7790.94
83_A88_Q0.7770.94
141_A180_D0.7730.94
93_D256_L0.7730.94
154_S254_A0.7710.94
264_G267_R0.7680.94
104_N308_R0.7680.94
46_S49_N0.7630.94
128_T133_P0.7620.94
163_L204_A0.7610.94
188_D191_T0.7600.94
9_T14_G0.7540.93
125_T247_A0.7530.93
138_S141_A0.7490.93
94_A98_L0.7450.93
163_L168_L0.7440.93
130_P240_P0.7410.93
267_R271_Q0.7390.93
74_A79_A0.7340.92
127_T242_L0.7340.92
61_L273_A0.7320.92
152_S155_G0.7320.92
77_H152_S0.7310.92
111_V271_Q0.7310.92
122_Y148_G0.7290.92
10_A14_G0.7210.92
153_T251_I0.7200.92
147_F206_G0.7190.92
279_E283_K0.7180.92
65_T270_V0.7160.91
14_G19_S0.7160.91
170_V181_F0.7140.91
61_L69_I0.7120.91
37_V262_W0.7100.91
19_S23_G0.7090.91
124_S159_P0.6920.90
178_V181_F0.6920.90
24_C34_D0.6870.90
95_S189_H0.6840.89
122_Y189_H0.6830.89
148_G189_H0.6830.89
293_F296_V0.6820.89
51_K55_A0.6820.89
208_G211_V0.6820.89
14_G24_C0.6810.89
103_D109_D0.6780.89
10_A15_T0.6770.89
12_A19_S0.6750.89
124_S206_G0.6750.89
10_A16_I0.6740.89
209_A247_A0.6700.88
192_A196_L0.6690.88
263_E267_R0.6650.88
259_R263_E0.6650.88
258_A270_V0.6600.88
74_A80_V0.6580.88
146_V192_A0.6570.88
109_D271_Q0.6530.87
138_S218_Q0.6510.87
262_W266_V0.6490.87
42_T94_A0.6460.87
99_A257_L0.6450.87
84_L257_L0.6450.87
13_A17_G0.6420.86
169_D178_V0.6420.86
130_P133_P0.6390.86
126_I245_L0.6360.86
113_I303_D0.6350.86
165_D249_D0.6340.86
113_I297_A0.6280.85
11_G18_I0.6280.85
262_W267_R0.6260.85
278_T281_D0.6260.85
97_T148_G0.6230.85
96_P153_T0.6230.85
64_E280_S0.6170.84
115_V120_S0.6160.84
113_I304_Y0.6140.84
162_M249_D0.6120.84
24_C31_G0.6110.83
95_S154_S0.6100.83
207_T211_V0.6060.83
195_Q201_E0.6030.83
122_Y153_T0.6030.83
64_E272_T0.6010.82
13_A21_L0.6000.82
37_V67_A0.6000.82
95_S208_G0.5980.82
12_A21_L0.5970.82
125_T212_S0.5940.82
129_Q133_P0.5940.82
166_A181_F0.5930.82
40_V79_A0.5930.82
122_Y155_G0.5930.82
146_V196_L0.5920.82
96_P254_A0.5920.82
128_T204_A0.5910.81
98_L153_T0.5880.81
128_T135_D0.5870.81
128_T140_L0.5870.81
93_D254_A0.5860.81
10_A13_A0.5820.80
84_L89_A0.5820.80
20_G23_G0.5810.80
30_G33_E0.5780.80
241_E244_L0.5780.80
18_I22_S0.5770.80
94_A189_H0.5760.80
101_V151_L0.5740.80
16_I20_G0.5720.79
208_G212_S0.5710.79
90_D261_S0.5710.79
255_P304_Y0.5700.79
148_G186_S0.5680.79
50_V73_V0.5670.79
80_V95_S0.5670.79
33_E263_E0.5660.79
17_G22_S0.5660.79
39_F256_L0.5650.78
163_L180_D0.5640.78
208_G253_R0.5640.78
206_G246_A0.5630.78
118_G122_Y0.5630.78
169_D218_Q0.5630.78
158_F248_S0.5590.78
189_H255_P0.5580.78
108_T257_L0.5570.77
59_D268_S0.5570.77
127_T205_A0.5560.77
98_L254_A0.5550.77
288_S296_V0.5520.77
77_H95_S0.5500.77
17_G32_G0.5490.76
10_A20_G0.5490.76
129_Q132_S0.5480.76
45_E190_N0.5480.76
81_L94_A0.5470.76
107_V112_G0.5460.76
140_L143_E0.5460.76
41_L71_P0.5460.76
202_Y205_A0.5450.76
44_A154_S0.5440.76
149_A185_W0.5420.76
34_D68_S0.5410.75
42_T54_Y0.5390.75
269_D272_T0.5380.75
77_H98_L0.5380.75
49_N52_E0.5370.75
102_G108_T0.5360.75
153_T208_G0.5360.75
157_L310_V0.5350.75
9_T16_I0.5320.74
139_D166_A0.5320.74
193_I242_L0.5320.74
16_I30_G0.5320.74
93_D96_P0.5310.74
60_Y280_S0.5310.74
277_A283_K0.5300.74
72_K83_A0.5300.74
52_E55_A0.5300.74
54_Y71_P0.5280.74
193_I221_L0.5270.74
57_V274_L0.5250.73
269_D273_A0.5240.73
148_G207_T0.5240.73
76_D190_N0.5210.73
152_S208_G0.5210.73
9_T12_A0.5210.73
273_A277_A0.5200.73
11_G16_I0.5190.72
45_E95_S0.5170.72
114_R293_F0.5170.72
262_W265_S0.5170.72
153_T157_L0.5170.72
84_L106_S0.5170.72
40_V71_P0.5160.72
54_Y95_S0.5150.72
37_V266_V0.5130.72
264_G272_T0.5120.71
11_G30_G0.5120.71
10_A17_G0.5110.71
212_S253_R0.5110.71
141_A163_L0.5110.71
140_L245_L0.5110.71
134_I139_D0.5100.71
44_A254_A0.5090.71
157_L304_Y0.5080.71
143_E204_A0.5070.71
99_A305_E0.5060.71
65_T68_S0.5040.70
62_E65_T0.5010.70
99_A308_R0.5000.70
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3ekiA 1 0.8313 100 0.369 Contact Map
3myuA 1 0.7969 100 0.419 Contact Map
3v83A 6 0.8688 100 0.426 Contact Map
1h45A 1 0.825 100 0.435 Contact Map
2d3iA 1 0.8313 100 0.44 Contact Map
1blfA 1 0.9219 100 0.442 Contact Map
1ryoA 1 0.8438 100 0.444 Contact Map
1iejA 1 0.8344 100 0.446 Contact Map
1cb6A 1 0.9125 100 0.449 Contact Map
3mc2A 1 0.8313 100 0.457 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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