GLNA - HALSA - GREMLIN Contacts

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GLNA - Glutamine synthetase

UniProt:	Q9HNI2	Sequences: MTNGDSSSSALTDNERAVLDDIEAQGIDFLRLQFTDILGTVKNVSIPAHQAEKAFTEGIYFDGSSIEGFVRIQESDMRLDPDPETFAVLPWRSNGDGGSARLICDVVDREGNAFAGGPRQVLKNVLARADDMGYSVSIGPEPEFFLFEKDDDGNATTTAHDQGGYFDLAPKDLASDIRREIIFTLEAMGFEIEASHHEVARGQHEINFKYDDALTTADNIATFRAVVRAVAEQHDVHATFMPKPIGEINGSGMHSHISLFDEDGENVFADNDDEFNLSETAYQFMGGVLEHAPAFTAVTNPTVNSYKRLVPGYEAPVYIAWSGVNRSALIRVPDAAGVSARFEIRSPDPSCNPYLALAAVIAAGLDGIDTDADPGDAVREDIYEFDEDKRDAYGIDTLPGHLGDAVTALESDPVMQDALGEHVCEKFAEAKRHEYAEYKASVSEWETDRYLEKF	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	454 (426)
Sequences:	6393 (3327)
Seq/√Len:	161.2

ECOLI - PUUA GLNA
BACSU - GLNA
HALSA - GLNA
SULSO - GLNA Q97VQ9 Q97W07

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
410_E	432_R	5.209	1.00
286_G	372_A	4.748	1.00
180_E	234_H	4.016	1.00
257_I	284_F	3.871	1.00
366_D	370_T	3.799	1.00
284_F	364_G	3.762	1.00
128_R	369_D	3.557	1.00
132_M	369_D	3.478	1.00
105_D	123_K	3.454	1.00
283_Q	371_D	3.375	1.00
108_D	112_N	3.082	1.00
290_E	370_T	2.959	1.00
127_A	131_D	2.844	1.00
421_E	425_E	2.805	1.00
145_F	200_A	2.779	1.00
177_I	181_I	2.770	1.00
125_V	362_A	2.757	1.00
416_Q	421_E	2.730	1.00
294_A	412_D	2.673	1.00
121_V	423_V	2.630	1.00
444_E	448_D	2.590	1.00
227_V	238_A	2.573	1.00
127_A	130_D	2.564	1.00
138_I	357_L	2.486	1.00
267_V	280_T	2.455	1.00
20_D	24_A	2.455	1.00
180_E	233_Q	2.431	1.00
211_D	219_N	2.402	1.00
279_E	371_D	2.399	1.00
211_D	215_T	2.397	1.00
257_I	360_V	2.364	1.00
291_H	366_D	2.282	1.00
291_H	412_D	2.277	1.00
298_V	359_A	2.258	1.00
401_H	404_D	2.233	1.00
282_Y	373_D	2.185	1.00
407_T	432_R	2.180	1.00
403_G	439_K	2.172	1.00
130_D	135_S	2.166	1.00
126_L	214_L	2.158	1.00
215_T	219_N	2.156	1.00
283_Q	286_G	2.143	1.00
299_T	356_A	2.079	1.00
297_A	409_L	2.062	1.00
21_D	25_Q	2.016	1.00
185_L	226_V	1.998	1.00
212_D	215_T	1.989	1.00
49_H	186_E	1.971	1.00
126_L	213_A	1.967	1.00
188_M	226_V	1.933	1.00
146_L	177_I	1.932	1.00
181_I	227_V	1.922	1.00
293_P	396_D	1.916	1.00
400_G	404_D	1.902	1.00
32_L	104_C	1.873	1.00
147_F	245_I	1.863	1.00
409_L	424_C	1.855	1.00
115_A	422_H	1.852	1.00
408_A	411_S	1.843	1.00
28_D	183_F	1.827	1.00
129_A	136_V	1.822	1.00
16_R	20_D	1.817	1.00
191_E	209_K	1.817	1.00
280_T	368_I	1.777	1.00
279_E	283_Q	1.768	1.00
437_E	449_R	1.765	1.00
126_L	212_D	1.764	1.00
294_A	414_V	1.762	1.00
277_L	281_A	1.754	1.00
286_G	374_P	1.724	1.00
283_Q	372_A	1.719	1.00
295_F	299_T	1.691	1.00
217_A	357_L	1.690	1.00
27_I	88_V	1.685	1.00
145_F	251_S	1.674	1.00
298_V	409_L	1.637	1.00
184_T	230_V	1.635	1.00
403_G	407_T	1.633	1.00
291_H	363_A	1.632	1.00
406_V	428_A	1.624	1.00
351_C	356_A	1.623	1.00
223_F	227_V	1.619	1.00
80_D	107_V	1.596	1.00
55_F	83_P	1.587	1.00
121_V	358_A	1.579	1.00
293_P	408_A	1.576	1.00
142_P	220_I	1.574	1.00
184_T	187_A	1.562	1.00
290_E	372_A	1.561	1.00
414_V	418_A	1.556	1.00
362_A	418_A	1.553	1.00
404_D	407_T	1.552	1.00
22_I	48_A	1.545	1.00
85_T	103_I	1.518	1.00
129_A	365_L	1.509	1.00
123_K	214_L	1.507	1.00
273_D	282_Y	1.501	1.00
381_D	384_E	1.470	1.00
410_E	428_A	1.457	1.00
33_Q	101_R	1.442	1.00
125_V	358_A	1.439	1.00
136_V	361_I	1.423	1.00
300_N	305_S	1.402	1.00
134_Y	267_V	1.388	1.00
185_L	190_F	1.378	1.00
146_L	231_A	1.365	1.00
283_Q	373_D	1.363	1.00
101_R	222_T	1.358	1.00
407_T	410_E	1.343	1.00
297_A	406_V	1.339	1.00
125_V	128_R	1.331	1.00
413_P	417_D	1.328	1.00
282_Y	374_P	1.322	1.00
216_T	219_N	1.321	1.00
296_T	300_N	1.321	1.00
208_F	216_T	1.313	1.00
20_D	23_E	1.304	1.00
148_E	158_T	1.302	1.00
279_E	373_D	1.301	1.00
407_T	411_S	1.298	1.00
344_I	360_V	1.296	1.00
35_T	221_A	1.291	1.00
279_E	282_Y	1.288	1.00
149_K	232_E	1.284	1.00
257_I	364_G	1.284	1.00
285_M	342_F	1.283	1.00
19_L	52_E	1.276	1.00
436_A	439_K	1.265	1.00
123_K	127_A	1.260	1.00
330_I	342_F	1.253	1.00
17_A	20_D	1.252	1.00
293_P	296_T	1.251	1.00
117_G	120_Q	1.242	1.00
416_Q	425_E	1.242	1.00
148_E	236_V	1.239	1.00
198_E	205_E	1.226	1.00
108_D	115_A	1.224	1.00
284_F	365_L	1.219	1.00
180_E	184_T	1.219	1.00
286_G	375_G	1.218	1.00
62_D	65_S	1.216	1.00
416_Q	424_C	1.216	1.00
294_A	415_M	1.210	1.00
137_S	260_F	1.198	1.00
200_A	249_N	1.198	1.00
28_D	186_E	1.188	1.00
86_F	100_A	1.188	1.00
431_K	434_E	1.185	1.00
294_A	408_A	1.182	1.00
295_F	359_A	1.181	1.00
128_R	362_A	1.179	1.00
410_E	425_E	1.174	1.00
280_T	283_Q	1.164	1.00
22_I	51_A	1.164	1.00
174_A	204_H	1.163	1.00
438_Y	445_W	1.162	1.00
436_A	440_A	1.156	1.00
409_L	415_M	1.147	1.00
285_M	330_I	1.137	1.00
226_V	230_V	1.135	1.00
62_D	66_I	1.134	1.00
41_V	103_I	1.131	1.00
62_D	70_V	1.129	1.00
230_V	234_H	1.128	1.00
79_L	106_V	1.127	1.00
291_H	370_T	1.127	1.00
295_F	363_A	1.121	1.00
296_T	346_S	1.121	1.00
27_I	100_A	1.115	1.00
137_S	210_Y	1.108	1.00
292_A	329_L	1.105	1.00
201_R	248_I	1.103	1.00
241_M	304_N	1.093	1.00
82_D	105_D	1.092	1.00
211_D	216_T	1.088	1.00
306_Y	402_L	1.086	0.99
194_A	207_N	1.086	0.99
129_A	132_M	1.083	0.99
255_S	360_V	1.078	0.99
63_G	66_I	1.070	0.99
289_L	330_I	1.064	0.99
284_F	360_V	1.061	0.99
113_A	120_Q	1.060	0.99
433_H	437_E	1.058	0.99
293_P	404_D	1.051	0.99
297_A	300_N	1.050	0.99
262_E	265_E	1.049	0.99
305_S	348_D	1.045	0.99
122_L	213_A	1.045	0.99
146_L	238_A	1.044	0.99
134_Y	280_T	1.044	0.99
79_L	104_C	1.043	0.99
153_G	156_T	1.041	0.99
323_G	377_A	1.036	0.99
145_F	249_N	1.029	0.99
442_V	446_E	1.027	0.99
52_E	56_T	1.026	0.99
297_A	427_F	1.024	0.99
18_V	86_F	1.019	0.99
147_F	239_T	1.018	0.99
246_G	442_V	1.017	0.99
205_E	254_H	1.016	0.99
131_D	369_D	1.016	0.99
184_T	233_Q	1.012	0.99
199_V	249_N	1.012	0.99
30_L	51_A	0.999	0.99
193_E	209_K	0.998	0.99
198_E	254_H	0.993	0.99
428_A	432_R	0.993	0.99
154_N	157_T	0.991	0.99
409_L	428_A	0.989	0.99
435_Y	439_K	0.988	0.99
184_T	226_V	0.980	0.99
269_A	276_N	0.979	0.99
307_K	446_E	0.978	0.99
231_A	238_A	0.972	0.99
87_A	101_R	0.968	0.99
41_V	221_A	0.962	0.99
286_G	373_D	0.962	0.99
425_E	429_E	0.954	0.99
303_V	402_L	0.950	0.99
329_L	346_S	0.949	0.99
68_G	71_R	0.949	0.99
293_P	319_I	0.948	0.99
412_D	416_Q	0.947	0.99
36_D	42_K	0.943	0.99
295_F	415_M	0.936	0.98
412_D	415_M	0.935	0.98
283_Q	368_I	0.933	0.98
65_S	70_V	0.933	0.98
255_S	356_A	0.931	0.98
177_I	236_V	0.930	0.98
206_I	223_F	0.925	0.98
288_V	330_I	0.924	0.98
296_T	299_T	0.924	0.98
208_F	223_F	0.922	0.98
121_V	125_V	0.918	0.98
28_D	94_N	0.917	0.98
188_M	222_T	0.917	0.98
438_Y	443_S	0.916	0.98
62_D	67_E	0.914	0.98
17_A	21_D	0.910	0.98
406_V	435_Y	0.906	0.98
320_A	395_I	0.903	0.98
66_I	69_F	0.902	0.98
432_R	436_A	0.900	0.98
73_Q	381_D	0.898	0.98
18_V	102_L	0.897	0.98
15_E	19_L	0.897	0.98
182_I	195_S	0.896	0.98
443_S	446_E	0.890	0.98
366_D	417_D	0.889	0.98
406_V	431_K	0.889	0.98
138_I	216_T	0.888	0.98
62_D	69_F	0.887	0.98
19_L	23_E	0.887	0.98
441_S	445_W	0.885	0.98
410_E	421_E	0.884	0.98
242_P	348_D	0.883	0.98
403_G	435_Y	0.883	0.98
220_I	253_M	0.876	0.98
117_G	121_V	0.875	0.98
242_P	350_S	0.873	0.98
295_F	300_N	0.867	0.98
176_D	234_H	0.864	0.97
141_E	205_E	0.863	0.97
410_E	413_P	0.862	0.97
30_L	48_A	0.858	0.97
382_I	385_F	0.856	0.97
268_F	281_A	0.856	0.97
424_C	428_A	0.856	0.97
141_E	198_E	0.854	0.97
177_I	234_H	0.853	0.97
385_F	395_I	0.851	0.97
140_P	220_I	0.846	0.97
336_A	339_S	0.843	0.97
129_A	259_L	0.842	0.97
177_I	230_V	0.842	0.97
427_F	431_K	0.840	0.97
175_S	179_R	0.838	0.97
92_R	99_S	0.837	0.97
320_A	328_A	0.837	0.97
84_E	215_T	0.836	0.97
298_V	424_C	0.835	0.97
442_V	445_W	0.835	0.97
335_A	339_S	0.832	0.97
25_Q	88_V	0.832	0.97
282_Y	286_G	0.831	0.97
116_G	422_H	0.830	0.97
162_Q	165_Y	0.830	0.97
154_N	158_T	0.826	0.97
134_Y	259_L	0.825	0.97
71_R	74_E	0.823	0.97
89_L	101_R	0.821	0.97
316_P	345_R	0.820	0.97
257_I	344_I	0.819	0.96
366_D	414_V	0.819	0.96
54_A	59_I	0.818	0.96
359_A	419_L	0.817	0.96
138_I	284_F	0.817	0.96
260_F	267_V	0.816	0.96
406_V	432_R	0.816	0.96
107_V	113_A	0.812	0.96
113_A	123_K	0.804	0.96
49_H	191_E	0.801	0.96
62_D	71_R	0.800	0.96
288_V	342_F	0.796	0.96
46_I	54_A	0.795	0.96
296_T	398_L	0.792	0.96
298_V	419_L	0.791	0.96
381_D	385_F	0.789	0.96
302_T	350_S	0.788	0.96
62_D	68_G	0.786	0.96
180_E	230_V	0.785	0.96
125_V	129_A	0.785	0.96
433_H	436_A	0.783	0.95
333_P	341_R	0.782	0.95
403_G	432_R	0.782	0.95
18_V	83_P	0.780	0.95
420_G	423_V	0.778	0.95
183_F	186_E	0.778	0.95
292_A	330_I	0.774	0.95
44_V	166_F	0.771	0.95
246_G	441_S	0.769	0.95
437_E	440_A	0.769	0.95
413_P	421_E	0.769	0.95
129_A	134_Y	0.768	0.95
63_G	71_R	0.766	0.95
107_V	120_Q	0.761	0.95
65_S	68_G	0.759	0.95
310_V	317_V	0.756	0.95
144_F	181_I	0.756	0.95
173_L	232_E	0.755	0.94
132_M	365_L	0.755	0.94
143_E	198_E	0.754	0.94
183_F	187_A	0.753	0.94
115_A	420_G	0.751	0.94
63_G	69_F	0.750	0.94
65_S	71_R	0.749	0.94
259_L	267_V	0.748	0.94
50_Q	53_K	0.748	0.94
408_A	412_D	0.747	0.94
301_P	305_S	0.745	0.94
125_V	418_A	0.744	0.94
132_M	267_V	0.744	0.94
159_A	165_Y	0.741	0.94
63_G	70_V	0.738	0.94
320_A	382_I	0.737	0.94
376_D	379_R	0.736	0.94
153_G	157_T	0.733	0.94
120_Q	124_N	0.733	0.94
378_V	382_I	0.732	0.94
115_A	120_Q	0.731	0.93
138_I	217_A	0.728	0.93
415_M	424_C	0.726	0.93
67_E	71_R	0.725	0.93
93_S	176_D	0.723	0.93
29_F	182_I	0.722	0.93
153_G	158_T	0.722	0.93
135_S	262_E	0.722	0.93
426_K	429_E	0.722	0.93
366_D	372_A	0.721	0.93
42_K	167_D	0.721	0.93
237_H	451_L	0.721	0.93
275_F	323_G	0.720	0.93
380_E	385_F	0.720	0.93
284_F	288_V	0.715	0.93
291_H	294_A	0.714	0.93
25_Q	86_F	0.712	0.93
15_E	56_T	0.708	0.92
105_D	117_G	0.708	0.92
358_A	419_L	0.707	0.92
299_T	412_D	0.707	0.92
288_V	344_I	0.706	0.92
259_L	361_I	0.706	0.92
136_V	257_I	0.705	0.92
327_S	382_I	0.705	0.92
190_F	208_F	0.703	0.92
270_D	273_D	0.700	0.92
258_S	341_R	0.697	0.92
121_V	124_N	0.696	0.92
38_L	430_A	0.693	0.92
182_I	192_I	0.690	0.91
128_R	131_D	0.689	0.91
321_W	332_V	0.689	0.91
191_E	219_N	0.689	0.91
447_T	451_L	0.689	0.91
82_D	85_T	0.688	0.91
241_M	307_K	0.688	0.91
245_I	248_I	0.688	0.91
199_V	314_E	0.687	0.91
165_Y	196_H	0.686	0.91
22_I	30_L	0.686	0.91
326_R	345_R	0.686	0.91
161_D	165_Y	0.686	0.91
296_T	399_P	0.686	0.91
438_Y	441_S	0.685	0.91
255_S	357_L	0.685	0.91
419_L	424_C	0.684	0.91
325_N	383_Y	0.683	0.91
328_A	382_I	0.678	0.91
303_V	438_Y	0.678	0.91
312_G	315_A	0.677	0.91
31_R	43_N	0.676	0.91
356_A	359_A	0.672	0.90
257_I	288_V	0.671	0.90
82_D	123_K	0.671	0.90
291_H	372_A	0.671	0.90
423_V	426_K	0.668	0.90
192_I	206_I	0.668	0.90
311_P	317_V	0.667	0.90
291_H	295_F	0.667	0.90
423_V	427_F	0.666	0.90
438_Y	449_R	0.666	0.90
307_K	438_Y	0.663	0.90
178_R	195_S	0.663	0.90
242_P	305_S	0.663	0.90
185_L	223_F	0.660	0.89
67_E	70_V	0.658	0.89
143_E	254_H	0.658	0.89
243_K	250_G	0.655	0.89
21_D	88_V	0.652	0.89
283_Q	374_P	0.652	0.89
63_G	67_E	0.652	0.89
290_E	396_D	0.650	0.89
217_A	353_P	0.642	0.88
51_A	102_L	0.641	0.88
120_Q	123_K	0.641	0.88
417_D	421_E	0.640	0.88
298_V	427_F	0.640	0.88
325_N	381_D	0.638	0.88
242_P	302_T	0.637	0.88
45_S	92_R	0.636	0.88
64_S	67_E	0.636	0.88
141_E	256_H	0.634	0.88
138_I	257_I	0.632	0.87
37_I	423_V	0.632	0.87
143_E	205_E	0.631	0.87
60_Y	335_A	0.631	0.87
126_L	130_D	0.630	0.87
55_F	58_G	0.629	0.87
124_N	128_R	0.627	0.87
268_F	361_I	0.626	0.87
190_F	222_T	0.625	0.87
327_S	383_Y	0.625	0.87
319_I	329_L	0.625	0.87
46_I	59_I	0.624	0.87
142_P	208_F	0.623	0.87
303_V	443_S	0.623	0.87
58_G	61_F	0.623	0.87
29_F	183_F	0.622	0.87
124_N	127_A	0.621	0.86
16_R	19_L	0.621	0.86
341_R	345_R	0.619	0.86
322_S	328_A	0.618	0.86
377_A	380_E	0.618	0.86
60_Y	78_R	0.617	0.86
34_F	66_I	0.617	0.86
112_N	115_A	0.617	0.86
108_D	114_F	0.615	0.86
146_L	181_I	0.614	0.86
172_D	229_A	0.614	0.86
149_K	237_H	0.614	0.86
417_D	420_G	0.613	0.86
160_H	163_G	0.613	0.86
139_G	207_N	0.612	0.86
294_A	413_P	0.611	0.86
181_I	226_V	0.611	0.86
141_E	254_H	0.610	0.85
92_R	176_D	0.609	0.85
369_D	372_A	0.609	0.85
89_L	188_M	0.609	0.85
155_A	158_T	0.609	0.85
93_S	99_S	0.608	0.85
292_A	295_F	0.607	0.85
33_Q	41_V	0.607	0.85
421_E	424_C	0.603	0.85
65_S	69_F	0.603	0.85
224_R	228_R	0.602	0.85
259_L	280_T	0.601	0.85
220_I	357_L	0.600	0.85
430_A	433_H	0.600	0.85
418_A	423_V	0.600	0.85
138_I	213_A	0.600	0.85
399_P	402_L	0.599	0.84
181_I	206_I	0.599	0.84
210_Y	258_S	0.599	0.84
278_S	281_A	0.596	0.84
32_L	54_A	0.594	0.84
265_E	338_V	0.594	0.84
87_A	222_T	0.593	0.84
316_P	327_S	0.593	0.84
29_F	45_S	0.592	0.84
135_S	212_D	0.591	0.84
34_F	79_L	0.591	0.84
437_E	445_W	0.590	0.84
135_S	260_F	0.590	0.84
145_F	248_I	0.590	0.84
91_W	226_V	0.587	0.83
380_E	383_Y	0.587	0.83
101_R	188_M	0.586	0.83
87_A	215_T	0.586	0.83
51_A	83_P	0.586	0.83
420_G	424_C	0.585	0.83
40_T	228_R	0.585	0.83
132_M	371_D	0.584	0.83
382_I	397_T	0.584	0.83
273_D	276_N	0.583	0.83
88_V	100_A	0.582	0.83
294_A	409_L	0.581	0.83
122_L	358_A	0.581	0.83
129_A	361_I	0.581	0.83
347_P	351_C	0.580	0.83
256_H	341_R	0.579	0.82
142_P	223_F	0.578	0.82
287_G	368_I	0.576	0.82
359_A	415_M	0.576	0.82
445_W	449_R	0.576	0.82
229_A	232_E	0.574	0.82
210_Y	213_A	0.573	0.82
364_G	367_G	0.573	0.82
225_A	229_A	0.573	0.82
300_N	304_N	0.572	0.82
174_A	236_V	0.570	0.81
288_V	360_V	0.569	0.81
347_P	356_A	0.569	0.81
153_G	448_D	0.569	0.81
303_V	446_E	0.568	0.81
150_D	154_N	0.567	0.81
139_G	196_H	0.566	0.81
295_F	298_V	0.566	0.81
50_Q	191_E	0.565	0.81
325_N	378_V	0.564	0.81
304_N	446_E	0.564	0.81
413_P	416_Q	0.563	0.81
205_E	343_E	0.562	0.81
193_E	210_Y	0.562	0.81
270_D	274_E	0.561	0.80
196_H	199_V	0.560	0.80
361_I	365_L	0.559	0.80
365_L	369_D	0.559	0.80
146_L	174_A	0.559	0.80
425_E	428_A	0.558	0.80
64_S	69_F	0.556	0.80
22_I	27_I	0.556	0.80
34_F	106_V	0.556	0.80
310_V	313_Y	0.556	0.80
159_A	162_Q	0.556	0.80
83_P	102_L	0.555	0.80
90_P	188_M	0.555	0.80
442_V	447_T	0.552	0.79
99_S	179_R	0.550	0.79
409_L	412_D	0.550	0.79
290_E	294_A	0.548	0.79
385_F	393_Y	0.548	0.79
403_G	410_E	0.547	0.79
254_H	343_E	0.546	0.79
298_V	355_L	0.545	0.78
379_R	385_F	0.545	0.78
147_F	244_P	0.544	0.78
437_E	441_S	0.543	0.78
250_G	308_R	0.543	0.78
159_A	163_G	0.543	0.78
275_F	282_Y	0.543	0.78
140_P	253_M	0.543	0.78
185_L	192_I	0.542	0.78
193_E	207_N	0.542	0.78
190_F	220_I	0.542	0.78
15_E	83_P	0.542	0.78
323_G	379_R	0.541	0.78
31_R	225_A	0.539	0.78
198_E	256_H	0.537	0.77
292_A	346_S	0.537	0.77
31_R	45_S	0.536	0.77
103_I	222_T	0.536	0.77
139_G	210_Y	0.536	0.77
54_A	57_E	0.535	0.77
412_D	424_C	0.535	0.77
415_M	419_L	0.534	0.77
128_R	132_M	0.534	0.77
146_L	236_V	0.534	0.77
72_I	75_S	0.534	0.77
297_A	305_S	0.533	0.77
292_A	319_I	0.533	0.77
299_T	344_I	0.533	0.77
378_V	385_F	0.533	0.77
29_F	92_R	0.533	0.77
165_Y	199_V	0.533	0.77
402_L	406_V	0.532	0.77
251_S	349_P	0.532	0.77
307_K	443_S	0.532	0.77
190_F	223_F	0.531	0.77
221_A	351_C	0.530	0.77
413_P	425_E	0.530	0.77
270_D	282_Y	0.529	0.76
33_Q	222_T	0.527	0.76
438_Y	442_V	0.527	0.76
43_N	168_L	0.527	0.76
270_D	279_E	0.526	0.76
65_S	199_V	0.526	0.76
296_T	405_A	0.526	0.76
365_L	368_I	0.525	0.76
72_I	314_E	0.524	0.76
270_D	276_N	0.523	0.76
422_H	425_E	0.522	0.75
275_F	377_A	0.522	0.75
141_E	326_R	0.522	0.75
122_L	214_L	0.521	0.75
318_Y	394_G	0.521	0.75
139_G	258_S	0.521	0.75
203_Q	251_S	0.521	0.75
326_R	343_E	0.520	0.75
303_V	435_Y	0.518	0.75
260_F	263_D	0.518	0.75
315_A	383_Y	0.517	0.75
179_R	183_F	0.517	0.75
148_E	160_H	0.517	0.75
145_F	243_K	0.514	0.74
199_V	313_Y	0.514	0.74
66_I	70_V	0.514	0.74
21_D	86_F	0.513	0.74
406_V	410_E	0.512	0.74
139_G	244_P	0.511	0.74
136_V	284_F	0.511	0.74
362_A	415_M	0.511	0.74
296_T	319_I	0.511	0.74
50_Q	193_E	0.508	0.74
94_N	183_F	0.508	0.74
401_H	435_Y	0.508	0.74
287_G	367_G	0.507	0.73
409_L	419_L	0.507	0.73
28_D	187_A	0.506	0.73
193_E	258_S	0.505	0.73
319_I	396_D	0.504	0.73
81_P	102_L	0.502	0.73
138_I	255_S	0.502	0.73
291_H	414_V	0.501	0.73
160_H	165_Y	0.501	0.73
370_T	373_D	0.500	0.72

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4lniA	5	0.9736	100	0.094	Contact Map
4acfA	5	0.9581	100	0.116	Contact Map
4s17A	5	0.9163	100	0.117	Contact Map
1f52A	5	0.9537	100	0.125	Contact Map
3ng0A	5	0.9427	100	0.129	Contact Map
4hppA	3	0.9009	100	0.138	Contact Map
2j9iA	5	0.9053	100	0.18	Contact Map
3o6xA	3	0.8414	100	0.336	Contact Map
3fkyA	8	0.7115	100	0.35	Contact Map
2ojwA	5	0.7599	100	0.361	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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