THSB - HALSA - GREMLIN Contacts

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THSB - Thermosome subunit beta

UniProt:	Q9HNI0	Sequences: MAQQQRMQGQPMIIMGDDAQRVKDRDAQEHNISAARAVADAVRSTLGPKGMDKMLVSSMGDVTVTNDGVTILQEMDIDNPTAEMIVEVAETQEDEAGDGTTTAVAIAGELLKNAEDLLERDIHPTAIIKGYNLAAEQAREEVDNVAVDVDPDDKDLIRSVAETSMTGKGAELDKELLSSIIYDAVNQVAVETNDGGIVVDAANINIETQTGHGVNESQLLRGAAISKDPVHDQMPAAVEDADVLLLNEAIEVEEAEADTSVNIESPDQLQSFLDQEEKQLKEKVQQIADTGANVVFCQKGIDDMAQHYLAKEGILAVRRTKKSDIEFLTNVLDASVVTDLDAASEADVVAGSVTRDSDDELFYVEGESEQAHGVTLLLRGSTDHVVDELERGVSDALDVSAQTLSDGRVLPGGGATEVEVASRLRDFADSVSGREQLAVEAFADSLELVPRVLAENAGLDSIDTLVDLRSAHENDDDEHIGLNVLSGDLEDTFEAGVVEPAHAKEQAVTSASEAANLVLKIDDIISAGDLSTDKGDDDGGAGGMGGGMGGGMGGMM	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	556 (497)
Sequences:	5542 (2409)
Seq/√Len:	108.0

ECOLI - CH60
BACSU - CH60
HALSA - THSB THSA
SULSO - THSA THSB THSG

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
146_A	501_A	4.376	1.00
137_Q	140_E	4.349	1.00
142_V	501_A	4.142	1.00
491_D	494_E	4.027	1.00
141_E	144_N	3.896	1.00
154_K	183_D	3.742	1.00
483_N	486_S	3.646	1.00
483_N	490_E	3.552	1.00
431_V	439_V	3.366	1.00
158_R	179_S	3.224	1.00
490_E	495_A	3.132	1.00
179_S	183_D	3.127	1.00
350_A	354_T	3.026	1.00
328_L	331_V	3.018	1.00
113_N	444_D	3.007	1.00
479_H	491_D	2.979	1.00
133_L	435_E	2.972	1.00
450_P	468_L	2.959	1.00
459_L	482_L	2.833	1.00
482_L	487_G	2.800	1.00
417_E	504_K	2.777	1.00
154_K	186_N	2.728	1.00
66_N	71_I	2.717	1.00
464_T	489_L	2.675	1.00
135_A	512_S	2.646	1.00
131_Y	512_S	2.644	1.00
351_G	366_G	2.587	1.00
424_L	439_V	2.550	1.00
135_A	508_V	2.529	1.00
351_G	354_T	2.509	1.00
346_A	349_V	2.462	1.00
285_Q	289_D	2.445	1.00
447_E	469_R	2.424	1.00
110_L	131_Y	2.398	1.00
350_A	353_V	2.359	1.00
467_D	470_S	2.327	1.00
132_N	516_N	2.283	1.00
425_R	443_A	2.242	1.00
142_V	416_T	2.240	1.00
329_T	332_L	2.206	1.00
328_L	332_L	2.187	1.00
137_Q	427_F	2.166	1.00
471_A	480_I	2.162	1.00
217_S	378_L	2.149	1.00
140_E	144_N	2.144	1.00
327_F	331_V	2.141	1.00
141_E	423_R	2.139	1.00
136_E	140_E	2.115	1.00
83_E	86_V	2.051	1.00
175_E	179_S	2.040	1.00
301_I	316_A	2.033	1.00
36_R	40_D	2.025	1.00
349_V	356_D	2.017	1.00
110_L	442_F	2.003	1.00
334_A	339_D	1.990	1.00
483_N	495_A	1.990	1.00
236_A	294_V	1.973	1.00
307_H	310_A	1.966	1.00
36_R	108_G	1.946	1.00
278_K	282_E	1.943	1.00
352_S	356_D	1.940	1.00
32_I	36_R	1.931	1.00
162_E	175_E	1.928	1.00
327_F	330_N	1.927	1.00
413_G	492_T	1.904	1.00
334_A	341_D	1.893	1.00
43_R	108_G	1.884	1.00
33_S	37_A	1.879	1.00
156_L	159_S	1.869	1.00
442_F	512_S	1.851	1.00
126_A	435_E	1.846	1.00
459_L	487_G	1.835	1.00
138_A	420_V	1.832	1.00
454_A	459_L	1.821	1.00
111_L	518_V	1.816	1.00
147_V	493_F	1.807	1.00
238_V	241_A	1.803	1.00
143_D	505_E	1.792	1.00
25_R	29_E	1.787	1.00
137_Q	423_R	1.784	1.00
533_D	536_D	1.778	1.00
490_E	497_V	1.768	1.00
423_R	426_D	1.758	1.00
471_A	477_D	1.757	1.00
427_F	439_V	1.749	1.00
154_K	179_S	1.736	1.00
427_F	430_S	1.713	1.00
141_E	145_V	1.713	1.00
131_Y	442_F	1.705	1.00
245_L	318_R	1.685	1.00
181_I	393_V	1.682	1.00
63_T	391_R	1.677	1.00
334_A	343_A	1.675	1.00
349_V	354_T	1.673	1.00
409_V	498_V	1.669	1.00
102_T	507_A	1.652	1.00
350_A	356_D	1.630	1.00
286_Q	289_D	1.629	1.00
418_V	450_P	1.626	1.00
343_A	347_D	1.620	1.00
21_R	523_D	1.617	1.00
39_A	108_G	1.601	1.00
30_H	33_S	1.599	1.00
339_D	343_A	1.592	1.00
391_R	394_S	1.592	1.00
117_L	437_L	1.573	1.00
334_A	337_V	1.562	1.00
185_V	404_L	1.541	1.00
139_R	143_D	1.538	1.00
109_E	112_K	1.531	1.00
140_E	143_D	1.524	1.00
467_D	471_A	1.522	1.00
138_A	446_L	1.509	1.00
240_D	267_D	1.503	1.00
454_A	461_S	1.482	1.00
128_I	132_N	1.477	1.00
342_A	345_E	1.473	1.00
93_E	391_R	1.470	1.00
61_D	384_H	1.468	1.00
337_V	343_A	1.467	1.00
66_N	391_R	1.456	1.00
134_A	442_F	1.452	1.00
117_L	122_I	1.442	1.00
467_D	488_D	1.435	1.00
419_E	478_E	1.429	1.00
421_A	469_R	1.421	1.00
426_D	429_D	1.414	1.00
36_R	112_K	1.413	1.00
238_V	270_Q	1.412	1.00
492_T	497_V	1.407	1.00
448_L	452_V	1.406	1.00
114_A	131_Y	1.406	1.00
288_A	314_I	1.405	1.00
341_D	346_A	1.403	1.00
351_G	356_D	1.400	1.00
327_F	332_L	1.400	1.00
447_E	451_R	1.399	1.00
129_K	435_E	1.390	1.00
416_T	420_V	1.381	1.00
212_H	216_E	1.377	1.00
424_L	443_A	1.371	1.00
337_V	341_D	1.365	1.00
238_V	294_V	1.353	1.00
245_L	334_A	1.336	1.00
237_A	352_S	1.332	0.99
436_Q	440_E	1.332	0.99
40_D	108_G	1.330	0.99
113_N	116_D	1.329	0.99
339_D	346_A	1.324	0.99
339_D	349_V	1.321	0.99
446_L	508_V	1.316	0.99
139_R	509_T	1.309	0.99
244_L	343_A	1.306	0.99
137_Q	439_V	1.300	0.99
272_F	312_E	1.283	0.99
415_A	419_E	1.281	0.99
137_Q	141_E	1.276	0.99
422_S	426_D	1.264	0.99
345_E	348_V	1.264	0.99
35_A	518_V	1.259	0.99
334_A	344_S	1.258	0.99
477_D	491_D	1.255	0.99
418_V	469_R	1.255	0.99
338_T	341_D	1.252	0.99
339_D	342_A	1.243	0.99
147_V	156_L	1.241	0.99
281_K	285_Q	1.231	0.99
80_P	524_I	1.229	0.99
480_I	489_L	1.218	0.99
405_S	502_H	1.216	0.99
350_A	355_R	1.215	0.99
138_A	424_L	1.214	0.99
261_V	264_E	1.212	0.99
80_P	526_S	1.205	0.99
180_I	217_S	1.205	0.99
210_T	378_L	1.204	0.99
155_D	158_R	1.203	0.99
93_E	398_D	1.200	0.99
32_I	111_L	1.196	0.99
349_V	352_S	1.196	0.99
66_N	166_T	1.185	0.99
427_F	431_V	1.177	0.99
334_A	346_A	1.175	0.99
440_E	444_D	1.174	0.99
466_V	470_S	1.162	0.99
150_D	156_L	1.156	0.99
328_L	364_V	1.155	0.99
440_E	443_A	1.151	0.99
450_P	454_A	1.150	0.98
133_L	137_Q	1.145	0.98
251_E	276_E	1.144	0.98
349_V	355_R	1.139	0.98
122_I	437_L	1.137	0.98
477_D	480_I	1.134	0.98
112_K	448_L	1.130	0.98
245_L	312_E	1.123	0.98
411_P	415_A	1.110	0.98
406_D	502_H	1.102	0.98
459_L	464_T	1.099	0.98
335_S	339_D	1.095	0.98
334_A	349_V	1.089	0.98
144_N	423_R	1.084	0.98
338_T	343_A	1.080	0.98
145_V	148_D	1.079	0.98
109_E	448_L	1.078	0.98
134_A	439_V	1.077	0.98
344_S	347_D	1.077	0.98
337_V	342_A	1.073	0.98
142_V	505_E	1.071	0.98
160_V	409_V	1.065	0.98
20_Q	526_S	1.062	0.97
93_E	394_S	1.052	0.97
245_L	320_T	1.047	0.97
391_R	398_D	1.040	0.97
362_F	365_E	1.034	0.97
411_P	493_F	1.032	0.97
343_A	346_A	1.031	0.97
353_V	356_D	1.031	0.97
65_T	388_E	1.026	0.97
357_S	363_Y	1.026	0.97
212_H	378_L	1.024	0.97
334_A	338_T	1.020	0.97
338_T	348_V	1.019	0.97
432_S	439_V	1.017	0.97
341_D	349_V	1.016	0.97
505_E	509_T	1.015	0.97
22_V	30_H	1.015	0.97
133_L	431_V	1.014	0.97
453_L	484_V	1.009	0.97
336_V	339_D	0.996	0.96
151_P	156_L	0.995	0.96
300_G	303_D	0.991	0.96
35_A	85_I	0.982	0.96
22_V	26_D	0.982	0.96
338_T	342_A	0.980	0.96
145_V	478_E	0.979	0.96
88_V	103_A	0.977	0.96
67_D	70_T	0.969	0.96
57_S	74_E	0.965	0.96
208_T	387_D	0.965	0.96
464_T	482_L	0.962	0.95
419_E	479_H	0.961	0.95
378_L	386_V	0.959	0.95
335_S	341_D	0.954	0.95
295_V	309_L	0.950	0.95
242_D	291_G	0.949	0.95
68_G	101_T	0.949	0.95
71_I	391_R	0.948	0.95
410_L	501_A	0.946	0.95
265_S	268_Q	0.942	0.95
274_D	278_K	0.940	0.95
479_H	493_F	0.938	0.95
142_V	420_V	0.936	0.95
145_V	420_V	0.936	0.95
219_L	296_F	0.934	0.95
432_S	435_E	0.932	0.95
393_V	397_L	0.932	0.95
32_I	115_E	0.930	0.95
183_D	187_Q	0.927	0.94
158_R	161_A	0.925	0.94
343_A	349_V	0.924	0.94
397_L	401_A	0.921	0.94
466_V	469_R	0.920	0.94
331_V	368_S	0.916	0.94
40_D	43_R	0.915	0.94
296_F	320_T	0.912	0.94
46_L	102_T	0.912	0.94
431_V	435_E	0.910	0.94
333_D	337_V	0.907	0.94
157_I	186_N	0.907	0.94
132_N	136_E	0.906	0.94
100_T	395_D	0.905	0.94
421_A	447_E	0.903	0.94
250_I	287_I	0.903	0.94
245_L	272_F	0.902	0.94
67_D	395_D	0.902	0.94
139_R	505_E	0.901	0.94
89_A	104_V	0.899	0.94
20_Q	528_G	0.896	0.93
388_E	391_R	0.893	0.93
500_P	503_A	0.890	0.93
35_A	111_L	0.890	0.93
357_S	362_F	0.888	0.93
101_T	395_D	0.888	0.93
43_R	452_V	0.887	0.93
529_D	533_D	0.885	0.93
527_A	530_L	0.884	0.93
433_G	436_Q	0.883	0.93
335_S	338_T	0.882	0.93
442_F	446_L	0.876	0.93
403_T	407_G	0.872	0.92
351_G	355_R	0.871	0.92
281_K	284_V	0.871	0.92
141_E	419_E	0.869	0.92
422_S	425_R	0.869	0.92
287_I	292_A	0.868	0.92
29_E	33_S	0.867	0.92
426_D	430_S	0.867	0.92
329_T	334_A	0.866	0.92
378_L	389_L	0.863	0.92
339_D	344_S	0.863	0.92
46_L	105_A	0.860	0.92
420_V	446_L	0.856	0.92
55_L	525_I	0.855	0.92
336_V	344_S	0.854	0.92
183_D	221_R	0.852	0.92
430_S	439_V	0.852	0.92
241_A	293_N	0.850	0.91
532_T	535_G	0.848	0.91
430_S	436_Q	0.848	0.91
483_N	497_V	0.847	0.91
187_Q	221_R	0.847	0.91
286_Q	292_A	0.843	0.91
411_P	479_H	0.843	0.91
419_E	468_L	0.839	0.91
493_F	498_V	0.836	0.91
322_K	326_E	0.835	0.91
344_S	348_V	0.833	0.91
18_D	528_G	0.833	0.91
20_Q	527_A	0.833	0.91
143_D	501_A	0.833	0.91
518_V	524_I	0.833	0.91
488_D	495_A	0.832	0.91
322_K	325_I	0.830	0.90
122_I	434_R	0.830	0.90
141_E	420_V	0.830	0.90
419_E	480_I	0.829	0.90
329_T	337_V	0.828	0.90
341_D	344_S	0.828	0.90
339_D	348_V	0.824	0.90
468_L	489_L	0.823	0.90
271_S	274_D	0.822	0.90
434_R	437_L	0.821	0.90
420_V	423_R	0.819	0.90
388_E	392_G	0.818	0.90
459_L	484_V	0.818	0.90
180_I	376_L	0.817	0.90
309_L	316_A	0.817	0.90
44_S	53_K	0.815	0.90
448_L	451_R	0.814	0.90
158_R	175_E	0.813	0.90
78_D	528_G	0.812	0.90
429_D	440_E	0.812	0.90
334_A	342_A	0.812	0.90
130_G	438_A	0.811	0.89
321_K	326_E	0.810	0.89
32_I	112_K	0.809	0.89
135_A	442_F	0.806	0.89
110_L	518_V	0.805	0.89
418_V	421_A	0.805	0.89
416_T	501_A	0.804	0.89
343_A	348_V	0.803	0.89
157_I	161_A	0.798	0.89
421_A	446_L	0.797	0.89
65_T	71_I	0.797	0.89
361_L	364_V	0.797	0.89
418_V	447_E	0.796	0.89
155_D	159_S	0.796	0.89
158_R	162_E	0.795	0.89
394_S	398_D	0.795	0.89
501_A	505_E	0.795	0.89
241_A	294_V	0.794	0.88
126_A	485_L	0.791	0.88
43_R	455_E	0.791	0.88
357_S	365_E	0.790	0.88
275_Q	297_C	0.789	0.88
268_Q	271_S	0.788	0.88
444_D	447_E	0.787	0.88
455_E	461_S	0.786	0.88
506_Q	509_T	0.783	0.88
161_A	400_S	0.780	0.88
57_S	61_D	0.780	0.88
184_A	211_G	0.778	0.87
357_S	360_E	0.778	0.87
154_K	158_R	0.778	0.87
160_V	399_V	0.775	0.87
304_M	359_D	0.773	0.87
39_A	43_R	0.772	0.87
528_G	532_T	0.772	0.87
333_D	339_D	0.770	0.87
359_D	362_F	0.767	0.87
335_S	347_D	0.767	0.87
130_G	134_A	0.767	0.87
336_V	341_D	0.767	0.87
349_V	353_V	0.767	0.87
376_L	393_V	0.765	0.87
238_V	293_N	0.764	0.86
73_Q	90_E	0.763	0.86
337_V	340_L	0.762	0.86
266_P	292_A	0.760	0.86
288_A	312_E	0.760	0.86
145_V	411_P	0.759	0.86
102_T	449_V	0.757	0.86
419_E	422_S	0.757	0.86
345_E	349_V	0.754	0.86
159_S	496_G	0.754	0.86
78_D	531_S	0.753	0.86
530_L	533_D	0.752	0.86
113_N	445_S	0.751	0.86
450_P	465_L	0.751	0.86
138_A	423_R	0.750	0.85
65_T	391_R	0.750	0.85
85_I	88_V	0.748	0.85
83_E	401_A	0.747	0.85
337_V	346_A	0.747	0.85
112_K	509_T	0.746	0.85
151_P	155_D	0.744	0.85
40_D	44_S	0.740	0.85
187_Q	374_V	0.740	0.85
433_G	437_L	0.739	0.85
481_G	492_T	0.738	0.85
490_E	494_E	0.737	0.84
341_D	348_V	0.735	0.84
160_V	403_T	0.734	0.84
223_A	234_M	0.733	0.84
247_N	324_D	0.733	0.84
185_V	397_L	0.731	0.84
126_A	432_S	0.729	0.84
185_V	204_I	0.729	0.84
221_R	365_E	0.729	0.84
135_A	139_R	0.729	0.84
68_G	395_D	0.729	0.84
334_A	348_V	0.728	0.84
245_L	329_T	0.728	0.84
214_V	389_L	0.725	0.83
242_D	267_D	0.725	0.83
127_I	442_F	0.721	0.83
333_D	342_A	0.720	0.83
447_E	460_D	0.720	0.83
145_V	416_T	0.719	0.83
329_T	336_V	0.718	0.83
326_E	329_T	0.718	0.83
34_A	79_N	0.718	0.83
441_A	444_D	0.716	0.83
57_S	63_T	0.716	0.83
357_S	361_L	0.714	0.83
246_L	250_I	0.714	0.83
425_R	440_E	0.714	0.83
317_V	362_F	0.713	0.82
138_A	141_E	0.713	0.82
137_Q	144_N	0.712	0.82
89_A	103_A	0.709	0.82
346_A	354_T	0.708	0.82
229_P	315_L	0.708	0.82
133_L	439_V	0.707	0.82
133_L	427_F	0.706	0.82
454_A	482_L	0.706	0.82
531_S	534_K	0.705	0.82
271_S	293_N	0.704	0.82
52_D	66_N	0.702	0.81
145_V	423_R	0.701	0.81
406_D	505_E	0.701	0.81
34_A	81_T	0.700	0.81
270_Q	274_D	0.700	0.81
46_L	449_V	0.700	0.81
430_S	433_G	0.696	0.81
234_M	300_G	0.695	0.81
429_D	436_Q	0.693	0.81
131_Y	438_A	0.693	0.81
425_R	444_D	0.692	0.81
58_S	530_L	0.690	0.80
47_G	50_G	0.687	0.80
118_L	485_L	0.687	0.80
528_G	534_K	0.685	0.80
528_G	533_D	0.684	0.80
467_D	489_L	0.684	0.80
422_S	469_R	0.683	0.80
486_S	490_E	0.683	0.80
411_P	492_T	0.682	0.80
304_M	308_Y	0.680	0.79
248_E	318_R	0.679	0.79
531_S	535_G	0.679	0.79
92_Q	510_S	0.679	0.79
274_D	305_A	0.676	0.79
118_L	127_I	0.673	0.79
138_A	508_V	0.673	0.79
333_D	343_A	0.672	0.79
131_Y	134_A	0.672	0.79
261_V	332_L	0.671	0.78
204_I	386_V	0.668	0.78
65_T	86_V	0.667	0.78
300_G	308_Y	0.666	0.78
346_A	350_A	0.664	0.78
418_V	465_L	0.663	0.78
208_T	390_E	0.663	0.78
252_V	255_A	0.663	0.78
72_L	104_V	0.662	0.78
424_L	427_F	0.662	0.78
38_V	85_I	0.661	0.77
106_I	511_A	0.660	0.77
31_N	524_I	0.660	0.77
337_V	348_V	0.657	0.77
181_I	396_A	0.657	0.77
166_T	391_R	0.655	0.77
468_L	471_A	0.655	0.77
126_A	129_K	0.654	0.77
161_A	182_Y	0.654	0.77
483_N	488_D	0.653	0.77
436_Q	439_V	0.651	0.76
162_E	178_S	0.651	0.76
282_E	285_Q	0.650	0.76
339_D	345_E	0.649	0.76
243_V	270_Q	0.648	0.76
336_V	342_A	0.646	0.76
421_A	443_A	0.644	0.76
347_D	351_G	0.644	0.76
321_K	324_D	0.642	0.75
79_N	83_E	0.641	0.75
141_E	424_L	0.640	0.75
166_T	388_E	0.638	0.75
286_Q	341_D	0.638	0.75
185_V	400_S	0.638	0.75
360_E	363_Y	0.637	0.75
503_A	507_A	0.636	0.75
143_D	146_A	0.636	0.75
482_L	488_D	0.632	0.74
175_E	485_L	0.631	0.74
507_A	511_A	0.631	0.74
454_A	464_T	0.630	0.74
248_E	323_S	0.624	0.73
137_Q	420_V	0.624	0.73
333_D	348_V	0.624	0.73
358_D	364_V	0.624	0.73
26_D	29_E	0.623	0.73
181_I	400_S	0.621	0.73
333_D	336_V	0.618	0.73
354_T	365_E	0.618	0.73
214_V	397_L	0.617	0.72
352_S	355_R	0.616	0.72
247_N	322_K	0.615	0.72
329_T	341_D	0.615	0.72
302_D	305_A	0.615	0.72
386_V	389_L	0.614	0.72
161_A	164_S	0.614	0.72
39_A	42_V	0.613	0.72
419_E	423_R	0.613	0.72
425_R	447_E	0.613	0.72
31_N	111_L	0.611	0.72
309_L	314_I	0.610	0.72
410_L	498_V	0.610	0.72
315_L	353_V	0.610	0.72
218_Q	333_D	0.609	0.71
525_I	528_G	0.608	0.71
296_F	364_V	0.607	0.71
231_H	234_M	0.606	0.71
135_A	509_T	0.606	0.71
354_T	371_A	0.606	0.71
410_L	416_T	0.605	0.71
60_G	314_I	0.605	0.71
54_M	518_V	0.604	0.71
106_I	296_F	0.604	0.71
160_V	407_G	0.604	0.71
298_Q	309_L	0.604	0.71
253_E	282_E	0.603	0.71
95_E	506_Q	0.603	0.71
282_E	286_Q	0.602	0.71
211_G	379_R	0.602	0.71
43_R	448_L	0.602	0.71
280_L	304_M	0.602	0.71
125_T	128_I	0.601	0.71
532_T	536_D	0.601	0.71
151_P	190_V	0.600	0.70
393_V	399_V	0.600	0.70
108_G	112_K	0.599	0.70
229_P	233_Q	0.595	0.70
68_G	97_G	0.595	0.70
107_A	511_A	0.594	0.70
180_I	211_G	0.593	0.69
506_Q	510_S	0.592	0.69
321_K	328_L	0.589	0.69
457_A	484_V	0.589	0.69
93_E	395_D	0.587	0.69
26_D	30_H	0.587	0.69
491_D	495_A	0.587	0.69
131_Y	135_A	0.587	0.69
321_K	331_V	0.585	0.68
467_D	480_I	0.584	0.68
329_T	340_L	0.584	0.68
73_Q	248_E	0.583	0.68
499_E	504_K	0.582	0.68
185_V	197_I	0.581	0.68
463_D	466_V	0.579	0.68
229_P	234_M	0.578	0.68
471_A	489_L	0.578	0.68
70_T	391_R	0.576	0.67
494_E	512_S	0.576	0.67
450_P	466_V	0.574	0.67
89_A	107_A	0.574	0.67
36_R	39_A	0.574	0.67
352_S	366_G	0.573	0.67
250_I	305_A	0.573	0.67
528_G	531_S	0.572	0.67
32_I	122_I	0.572	0.67
63_T	74_E	0.571	0.67
336_V	346_A	0.569	0.66
350_A	371_A	0.568	0.66
25_R	245_L	0.567	0.66
260_S	383_D	0.566	0.66
319_R	324_D	0.566	0.66
262_N	266_P	0.566	0.66
321_K	329_T	0.565	0.66
117_L	519_L	0.563	0.66
454_A	465_L	0.563	0.66
22_V	528_G	0.563	0.66
245_L	296_F	0.562	0.65
29_E	32_I	0.562	0.65
84_M	514_A	0.562	0.65
68_G	100_T	0.561	0.65
244_L	290_T	0.561	0.65
157_I	400_S	0.561	0.65
329_T	338_T	0.560	0.65
36_R	115_E	0.558	0.65
331_V	348_V	0.556	0.65
70_T	395_D	0.556	0.65
368_S	371_A	0.554	0.64
452_V	455_E	0.552	0.64
337_V	344_S	0.551	0.64
123_H	520_K	0.550	0.64
285_Q	312_E	0.550	0.64
42_V	101_T	0.549	0.64
213_G	294_V	0.548	0.63
114_A	442_F	0.547	0.63
383_D	387_D	0.547	0.63
116_D	120_R	0.547	0.63
174_K	499_E	0.547	0.63
346_A	356_D	0.546	0.63
127_I	424_L	0.545	0.63
83_E	87_E	0.544	0.63
352_S	365_E	0.544	0.63
31_N	54_M	0.544	0.63
31_N	80_P	0.544	0.63
530_L	534_K	0.543	0.63
20_Q	29_E	0.543	0.63
242_D	262_N	0.543	0.63
231_H	255_A	0.543	0.63
143_D	406_D	0.542	0.63
319_R	327_F	0.542	0.63
333_D	349_V	0.542	0.63
114_A	130_G	0.542	0.63
324_D	491_D	0.541	0.62
229_P	238_V	0.540	0.62
117_L	441_A	0.540	0.62
138_A	443_A	0.540	0.62
143_D	148_D	0.540	0.62
449_V	453_L	0.539	0.62
28_Q	522_D	0.539	0.62
239_E	352_S	0.539	0.62
231_H	237_A	0.537	0.62
37_A	243_V	0.536	0.62
527_A	533_D	0.536	0.62
279_Q	282_E	0.536	0.62
261_V	265_S	0.536	0.62
284_V	288_A	0.536	0.62
31_N	518_V	0.535	0.62
333_D	341_D	0.535	0.62
358_D	361_L	0.534	0.61
238_V	268_Q	0.534	0.61
443_A	447_E	0.534	0.61
375_T	379_R	0.534	0.61
108_G	111_L	0.534	0.61
281_K	289_D	0.533	0.61
111_L	439_V	0.533	0.61
160_V	274_D	0.532	0.61
471_A	478_E	0.532	0.61
122_I	433_G	0.532	0.61
55_L	482_L	0.531	0.61
363_Y	366_G	0.531	0.61
207_E	518_V	0.529	0.61
347_D	350_A	0.529	0.61
165_M	177_L	0.529	0.61
158_R	182_Y	0.528	0.61
447_E	465_L	0.528	0.61
246_L	297_C	0.528	0.61
159_S	162_E	0.527	0.60
147_V	479_H	0.527	0.60
469_R	480_I	0.527	0.60
348_V	355_R	0.526	0.60
55_L	74_E	0.526	0.60
195_G	198_V	0.525	0.60
220_L	224_A	0.525	0.60
242_D	265_S	0.525	0.60
284_V	287_I	0.525	0.60
187_Q	215_N	0.524	0.60
399_V	403_T	0.524	0.60
329_T	343_A	0.524	0.60
157_I	160_V	0.523	0.60
205_N	209_Q	0.523	0.60
444_D	448_L	0.523	0.60
422_S	480_I	0.523	0.60
65_T	166_T	0.522	0.60
321_K	330_N	0.521	0.60
218_Q	377_L	0.521	0.60
149_V	403_T	0.521	0.60
278_K	285_Q	0.519	0.59
333_D	340_L	0.519	0.59
246_L	274_D	0.518	0.59
359_D	365_E	0.516	0.59
279_Q	283_K	0.515	0.59
480_I	490_E	0.515	0.59
32_I	208_T	0.514	0.59
307_H	311_K	0.514	0.59
84_M	386_V	0.513	0.58
129_K	516_N	0.512	0.58
243_V	364_V	0.512	0.58
447_E	487_G	0.512	0.58
269_L	314_I	0.512	0.58
267_D	271_S	0.511	0.58
163_T	499_E	0.511	0.58
204_I	397_L	0.510	0.58
184_A	188_V	0.510	0.58
342_A	347_D	0.510	0.58
530_L	536_D	0.510	0.58
66_N	111_L	0.509	0.58
411_P	478_E	0.509	0.58
206_I	378_L	0.509	0.58
460_D	465_L	0.508	0.58
242_D	348_V	0.508	0.58
161_A	178_S	0.508	0.58
444_D	462_I	0.508	0.58
510_S	519_L	0.507	0.58
111_L	247_N	0.507	0.58
134_A	155_D	0.506	0.57
145_V	419_E	0.506	0.57
287_I	290_T	0.506	0.57
333_D	378_L	0.506	0.57
209_Q	359_D	0.506	0.57
258_D	262_N	0.505	0.57
529_D	532_T	0.504	0.57
92_Q	103_A	0.503	0.57
111_L	517_L	0.503	0.57
137_Q	426_D	0.503	0.57
46_L	101_T	0.503	0.57
318_R	321_K	0.503	0.57
111_L	294_V	0.502	0.57
190_V	372_H	0.502	0.57
67_D	380_G	0.501	0.57
217_S	315_L	0.501	0.57
97_G	395_D	0.501	0.57
33_S	36_R	0.501	0.57
221_R	366_G	0.501	0.57
195_G	515_A	0.501	0.57
69_V	73_Q	0.500	0.57
421_A	448_L	0.500	0.57
155_D	494_E	0.500	0.57
204_I	253_E	0.500	0.57
304_M	307_H	0.500	0.57

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3j1bA	4	0.9119	100	0.088	Contact Map
1q3qA	4	0.9263	100	0.089	Contact Map
3ruvA	6	0.9227	100	0.1	Contact Map
1a6dA	2	0.8993	100	0.108	Contact Map
3p9dG	1	0.9047	100	0.109	Contact Map
3ko1A	5	0.9029	100	0.118	Contact Map
1a6dB	2	0.8975	100	0.127	Contact Map
3p9dA	1	0.9424	100	0.138	Contact Map
3p9dE	1	0.9191	100	0.143	Contact Map
3iygA	1	0.9209	100	0.148	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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