GREMLIN Database
Q9HNH7 - Uncharacterized protein
UniProt: Q9HNH7 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 127 (116)
Sequences: 6489 (4122)
Seq/√Len: 382.7

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
52_R94_E3.2631.00
59_K69_M2.9491.00
67_L71_D2.7991.00
74_K120_E2.5351.00
46_P49_V2.4941.00
48_D87_A2.4101.00
77_V88_M2.1001.00
78_F106_V2.0861.00
52_R56_E2.0751.00
107_E110_A2.0641.00
48_D90_A2.0171.00
56_E95_Y1.9281.00
58_V121_A1.9101.00
33_I115_V1.8361.00
62_L123_A1.8001.00
50_Q116_G1.7821.00
59_K63_E1.7451.00
110_A114_G1.6421.00
53_Q57_N1.6211.00
42_I115_V1.6181.00
75_V121_A1.6171.00
84_D116_G1.5981.00
52_R95_Y1.5511.00
27_V67_L1.5381.00
23_D73_L1.5061.00
56_E59_K1.5001.00
82_M107_E1.4711.00
47_I51_T1.4691.00
79_M88_M1.4641.00
68_N71_D1.4281.00
23_D124_A1.3781.00
36_T39_G1.3701.00
53_Q56_E1.3631.00
79_M105_A1.3471.00
34_P115_V1.3441.00
22_T25_D1.3381.00
28_F122_I1.3241.00
104_S120_E1.3151.00
31_G118_E1.2561.00
72_V121_A1.2331.00
41_L113_K1.2211.00
89_N103_R1.2061.00
87_A90_A1.2061.00
36_T43_A1.1981.00
80_D84_D1.1871.00
91_A94_E1.1561.00
29_T61_I1.1471.00
22_T27_V1.1471.00
62_L67_L1.1331.00
27_V65_E1.1211.00
84_D87_A1.1091.00
92_Y103_R1.0821.00
80_D110_A1.0791.00
10_A19_Q1.0771.00
9_D63_E1.0701.00
78_F108_V1.0671.00
26_V124_A1.0661.00
34_P54_S1.0621.00
52_R91_A1.0551.00
76_S120_E1.0501.00
22_T67_L1.0481.00
29_T121_A1.0331.00
97_Q100_P1.0231.00
47_I88_M1.0151.00
78_F104_S1.0141.00
26_V73_L1.0121.00
90_A93_K1.0081.00
62_L72_V0.9941.00
51_T88_M0.9891.00
63_E68_N0.9871.00
72_V96_F0.9861.00
80_D114_G0.9501.00
32_Q61_I0.9501.00
83_D110_A0.9471.00
90_A94_E0.9201.00
20_A61_I0.9201.00
81_D84_D0.9061.00
80_D116_G0.9061.00
44_D49_V0.9021.00
59_K95_Y0.8791.00
60_A63_E0.8671.00
69_M72_V0.8601.00
48_D91_A0.8591.00
41_L44_D0.8421.00
91_A95_Y0.8301.00
80_D109_A0.8261.00
55_L95_Y0.8161.00
34_P50_Q0.8151.00
47_I84_D0.8121.00
85_F105_A0.8101.00
37_P53_Q0.8051.00
55_L119_I0.7981.00
48_D52_R0.7951.00
75_V96_F0.7941.00
75_V92_Y0.7871.00
80_D108_V0.7821.00
93_K100_P0.7741.00
70_Q97_Q0.7721.00
55_L69_M0.7631.00
69_M95_Y0.7401.00
35_M40_E0.7351.00
47_I91_A0.7331.00
46_P116_G0.7251.00
43_A53_Q0.7221.00
89_N92_Y0.7121.00
72_V123_A0.7121.00
51_T117_V0.7101.00
47_I117_V0.7041.00
25_D124_A0.7000.99
45_E50_Q0.6920.99
9_D60_A0.6900.99
78_F120_E0.6880.99
14_V113_K0.6870.99
36_T41_L0.6860.99
55_L92_Y0.6840.99
16_A89_N0.6740.99
77_V119_I0.6740.99
20_A27_V0.6730.99
29_T58_V0.6710.99
67_L124_A0.6690.99
19_Q61_I0.6690.99
20_A65_E0.6600.99
45_E49_V0.6570.99
49_V52_R0.6510.99
27_V123_A0.6500.99
76_S104_S0.6490.99
54_S119_I0.6470.99
48_D94_E0.6470.99
79_M82_M0.6390.99
82_M110_A0.6190.99
37_P60_A0.6180.99
56_E60_A0.6070.99
86_D90_A0.6040.99
39_G43_A0.6040.99
47_I87_A0.6020.98
43_A49_V0.6000.98
74_K104_S0.5950.98
85_F112_P0.5920.98
44_D50_Q0.5920.98
19_Q64_A0.5890.98
33_I113_K0.5840.98
21_A73_L0.5840.98
43_A46_P0.5830.98
81_D116_G0.5790.98
23_D28_F0.5760.98
46_P87_A0.5750.98
46_P50_Q0.5720.98
62_L121_A0.5720.98
61_I64_A0.5670.98
30_A102_A0.5610.98
72_V75_V0.5610.98
62_L69_M0.5570.98
44_D116_G0.5550.97
89_N93_K0.5550.97
77_V103_R0.5550.97
24_G124_A0.5530.97
33_I54_S0.5460.97
17_Y31_G0.5430.97
70_Q98_D0.5420.97
32_Q58_V0.5400.97
67_L123_A0.5370.97
34_P42_I0.5370.97
80_D107_E0.5290.97
79_M84_D0.5250.96
23_D26_V0.5240.96
18_S21_A0.5240.96
26_V122_I0.5210.96
54_S117_V0.5190.96
53_Q60_A0.5120.96
36_T40_E0.5100.96
32_Q57_N0.5060.96
9_D38_D0.5050.96
81_D107_E0.5010.95
21_A102_A0.5000.95
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2b33A 3 0.9921 100 0.119 Contact Map
2dyyA 3 0.9921 100 0.132 Contact Map
1xrgA 3 0.9843 100 0.134 Contact Map
1qahA 3 1 100 0.141 Contact Map
3vczA 5 0.9685 100 0.148 Contact Map
3l7qA 3 0.9764 100 0.148 Contact Map
3r0pA 5 0.9843 100 0.149 Contact Map
1x25A 3 0.9921 100 0.151 Contact Map
3m1xA 3 0.9764 100 0.152 Contact Map
3k0tA 3 0.9764 100 0.154 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0065 seconds.