Q9HNF7 - HALSA - GREMLIN Contacts

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Q9HNF7 - Na+/H+ antiporter

UniProt:	Q9HNF7	Sequences: MSDFTPLAYEDIDDARKPTLTEALVPVLVVVVSLGVGSGYLGLAPHAPLLWSITFTGLFARYHLGYDWERVSDAALAGLRMGLQAILILFVIYGLIATWTSAGTIPGLMYYGLGALTPAVFLPVTAILAAVVAFAIGSSWTTVGTLGVAFVGIGSGLGIPLPMTAGAIVSGAYAGDKQSPLSDTTNLAAAVTNADLYDHINGMRLGTAIAFGLSVLAYAVLGVLIVDGGAANVTAISGPLAGSYALGPLVFLPLVVTFGLAFRGYPALPSLVAGVFAGALTTIAVQGASFTAAWDIFLNGTTPETGSELVNNLLTTGGIAGSAWTIAVVVAALSLGGLLERTGVLPTLTHHLTRAIWSPESLVAGTGVAAIATNAFSAQQYMSIVVPSVSLRTLYDEYDLNERDLSRAVEAAGTPTGPFFPWHAGAVFMTGALYTSQPGAISWWWAPYYFFGILSPLVLFGLVLAGRGYDRAGSATQPAAPAANAAATDDD	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	491 (435)
Sequences:	2190 (1445)
Seq/√Len:	69.3

BACSU - MLEN NHAC
HALSA - Q9HNF7 Q9HS26 ARCD

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
217_A	450_F	6.297	1.00
138_S	141_T	4.934	1.00
360_E	464_L	4.084	1.00
396_D	402_E	3.948	1.00
256_V	277_A	3.912	1.00
154_G	164_T	3.469	1.00
130_A	211_F	3.406	1.00
143_V	429_M	3.344	1.00
212_G	216_L	3.251	1.00
123_P	215_V	2.994	1.00
178_Q	204_R	2.962	1.00
67_D	70_R	2.958	1.00
358_S	361_S	2.931	1.00
202_G	404_D	2.917	1.00
123_P	219_A	2.860	1.00
151_V	161_L	2.806	1.00
213_L	454_L	2.802	1.00
366_T	395_Y	2.668	1.00
98_T	297_F	2.604	1.00
360_E	463_V	2.599	1.00
289_S	292_A	2.563	1.00
90_F	319_I	2.440	1.00
364_A	464_L	2.405	1.00
351_H	354_R	2.393	1.00
257_T	274_G	2.377	1.00
114_G	237_S	2.357	1.00
122_L	163_M	2.339	1.00
340_E	389_V	2.309	1.00
77_A	341_R	2.286	1.00
125_T	150_F	2.267	1.00
442_S	446_A	2.251	1.00
126_A	211_F	2.227	1.00
107_G	246_L	2.223	1.00
374_N	416_T	2.212	1.00
375_A	420_F	2.196	1.00
167_A	218_Y	2.190	1.00
449_Y	452_G	2.179	1.00
193_N	402_E	2.157	1.00
367_G	412_A	2.151	1.00
369_A	391_L	2.134	1.00
279_A	293_A	2.100	1.00
367_G	460_F	2.081	1.00
450_F	454_L	2.063	1.00
107_G	111_Y	2.036	1.00
259_G	263_R	2.026	1.00
77_A	80_R	1.979	1.00
194_A	402_E	1.972	1.00
400_L	404_D	1.956	1.00
74_A	341_R	1.946	1.00
101_S	296_I	1.944	1.00
274_G	278_G	1.935	1.00
98_T	275_V	1.924	1.00
44_A	48_P	1.905	1.00
20_L	351_H	1.901	1.00
60_A	71_V	1.899	1.00
216_L	220_V	1.895	1.00
210_A	454_L	1.869	1.00
213_L	458_V	1.868	1.00
240_L	246_L	1.833	1.00
430_T	442_S	1.830	1.00
91_V	268_L	1.824	1.00
219_A	223_V	1.810	1.00
245_A	248_P	1.802	1.00
107_G	251_F	1.784	1.00
195_D	198_D	1.784	1.00
104_T	253_P	1.768	1.00
206_G	411_A	1.767	1.00
457_L	461_G	1.740	1.00
371_I	416_T	1.736	1.00
20_L	348_L	1.727	1.00
450_F	453_I	1.726	1.00
298_L	320_A	1.711	1.00
403_R	470_D	1.681	1.00
214_S	218_Y	1.677	1.00
295_D	299_N	1.661	0.99
189_A	194_A	1.633	0.99
283_I	293_A	1.633	0.99
159_I	164_T	1.632	0.99
234_T	238_G	1.622	0.99
154_G	161_L	1.610	0.99
260_L	273_A	1.608	0.99
96_I	144_G	1.591	0.99
36_V	41_L	1.585	0.99
323_A	327_A	1.581	0.99
163_M	221_L	1.531	0.99
370_A	409_V	1.531	0.99
346_P	350_H	1.529	0.99
239_P	311_N	1.526	0.99
160_P	225_I	1.523	0.99
111_Y	248_P	1.518	0.99
357_W	361_S	1.515	0.99
82_G	333_L	1.513	0.99
184_T	384_I	1.500	0.99
60_A	342_T	1.498	0.99
35_G	39_G	1.495	0.99
165_A	433_L	1.494	0.99
461_G	465_A	1.491	0.99
29_V	55_F	1.487	0.99
428_F	432_A	1.486	0.99
54_T	272_V	1.471	0.99
363_V	404_D	1.463	0.99
280_L	284_A	1.461	0.99
191_V	388_S	1.455	0.99
198_D	403_R	1.439	0.98
443_W	446_A	1.438	0.98
367_G	459_L	1.433	0.98
98_T	279_A	1.429	0.98
194_A	198_D	1.425	0.98
189_A	193_N	1.425	0.98
213_L	217_A	1.415	0.98
249_L	281_T	1.408	0.98
250_V	281_T	1.407	0.98
449_Y	453_I	1.406	0.98
78_G	337_G	1.395	0.98
177_K	410_E	1.394	0.98
166_G	170_S	1.390	0.98
164_T	168_I	1.382	0.98
170_S	218_Y	1.382	0.98
221_L	450_F	1.377	0.98
90_F	323_A	1.374	0.98
408_A	459_L	1.369	0.98
100_T	316_T	1.366	0.98
98_T	278_G	1.363	0.98
388_S	409_V	1.360	0.98
255_V	259_G	1.354	0.98
217_A	221_L	1.351	0.98
101_S	282_T	1.345	0.98
364_A	460_F	1.342	0.98
392_R	396_D	1.326	0.97
169_V	426_A	1.321	0.97
281_T	285_V	1.310	0.97
417_G	425_G	1.308	0.97
203_M	410_E	1.300	0.97
158_G	161_L	1.300	0.97
111_Y	251_F	1.298	0.97
22_E	63_H	1.298	0.97
446_A	453_I	1.286	0.97
202_G	403_R	1.284	0.97
417_G	423_H	1.278	0.97
288_A	296_I	1.273	0.97
393_T	397_E	1.259	0.96
282_T	288_A	1.253	0.96
207_T	455_S	1.248	0.96
415_P	455_S	1.246	0.96
87_L	268_L	1.243	0.96
237_S	241_A	1.241	0.96
127_I	215_V	1.231	0.96
250_V	285_V	1.229	0.96
210_A	455_S	1.228	0.96
122_L	159_I	1.222	0.96
462_L	468_G	1.215	0.96
147_G	165_A	1.214	0.96
419_F	453_I	1.204	0.95
177_K	414_T	1.200	0.95
215_V	219_A	1.192	0.95
25_V	55_F	1.187	0.95
442_S	445_W	1.181	0.95
97_A	101_S	1.181	0.95
76_L	80_R	1.179	0.95
217_A	454_L	1.177	0.95
151_V	165_A	1.170	0.95
320_A	324_W	1.162	0.94
45_P	48_P	1.161	0.94
214_S	454_L	1.159	0.94
411_A	459_L	1.155	0.94
248_P	255_V	1.154	0.94
407_R	411_A	1.153	0.94
94_G	297_F	1.152	0.94
362_L	394_L	1.149	0.94
68_W	269_P	1.148	0.94
360_E	460_F	1.147	0.94
308_E	312_N	1.145	0.94
111_Y	246_L	1.137	0.94
173_Y	429_M	1.137	0.94
193_N	392_R	1.134	0.94
185_T	410_E	1.128	0.93
299_N	320_A	1.127	0.93
73_D	80_R	1.125	0.93
24_L	28_L	1.122	0.93
174_A	410_E	1.120	0.93
130_A	174_A	1.119	0.93
340_E	346_P	1.115	0.93
70_R	73_D	1.114	0.93
370_A	413_G	1.100	0.93
453_I	457_L	1.099	0.93
320_A	323_A	1.098	0.92
379_Q	383_S	1.098	0.92
394_L	397_E	1.093	0.92
18_P	347_T	1.092	0.92
204_R	208_A	1.088	0.92
75_A	334_S	1.086	0.92
252_L	281_T	1.073	0.92
150_F	168_I	1.072	0.92
56_T	338_L	1.070	0.92
410_E	414_T	1.069	0.91
249_L	252_L	1.066	0.91
45_P	49_L	1.062	0.91
162_P	444_W	1.056	0.91
151_V	435_T	1.056	0.91
85_A	381_Y	1.044	0.90
29_V	59_F	1.041	0.90
125_T	167_A	1.041	0.90
154_G	158_G	1.039	0.90
173_Y	423_H	1.031	0.90
169_V	377_S	1.025	0.90
358_S	398_Y	1.024	0.90
19_T	22_E	1.022	0.90
116_L	124_V	1.020	0.89
363_V	463_V	1.018	0.89
359_P	398_Y	1.018	0.89
104_T	250_V	1.015	0.89
107_G	250_V	1.014	0.89
69_E	73_D	1.013	0.89
451_F	455_S	1.010	0.89
325_T	425_G	1.004	0.89
347_T	351_H	1.003	0.89
252_L	277_A	1.002	0.89
69_E	127_I	0.998	0.88
454_L	458_V	0.998	0.88
128_L	150_F	0.996	0.88
394_L	398_Y	0.994	0.88
199_H	406_S	0.990	0.88
236_I	310_V	0.985	0.88
247_G	250_V	0.984	0.88
86_I	326_I	0.983	0.88
50_L	94_G	0.979	0.87
210_A	458_V	0.976	0.87
43_L	48_P	0.972	0.87
419_F	449_Y	0.968	0.87
112_G	244_Y	0.966	0.87
74_A	337_G	0.965	0.87
43_L	46_H	0.960	0.86
364_A	368_V	0.959	0.86
260_L	265_Y	0.955	0.86
129_A	146_L	0.941	0.85
129_A	133_A	0.940	0.85
178_Q	208_A	0.940	0.85
380_Q	456_P	0.939	0.85
209_I	212_G	0.935	0.85
291_T	295_D	0.932	0.85
207_T	410_E	0.925	0.84
19_T	23_A	0.923	0.84
415_P	451_F	0.922	0.84
187_L	384_I	0.919	0.84
206_G	407_R	0.919	0.84
73_D	77_A	0.915	0.84
57_G	61_R	0.915	0.84
151_V	155_S	0.915	0.84
458_V	461_G	0.914	0.84
91_V	275_V	0.914	0.84
79_L	87_L	0.909	0.83
192_T	406_S	0.908	0.83
93_Y	322_S	0.907	0.83
420_F	423_H	0.901	0.83
57_G	338_L	0.899	0.83
359_P	400_L	0.898	0.82
360_E	364_A	0.897	0.82
86_I	329_V	0.894	0.82
214_S	217_A	0.892	0.82
235_A	238_G	0.890	0.82
130_A	134_F	0.887	0.82
393_T	396_D	0.887	0.82
165_A	435_T	0.887	0.82
356_I	361_S	0.885	0.82
22_E	64_L	0.883	0.81
116_L	120_V	0.882	0.81
317_G	321_G	0.882	0.81
256_V	259_G	0.881	0.81
430_T	441_I	0.880	0.81
157_L	164_T	0.875	0.81
371_I	375_A	0.874	0.81
234_T	237_S	0.873	0.81
122_L	160_P	0.873	0.81
288_A	292_A	0.871	0.80
177_K	207_T	0.870	0.80
169_V	429_M	0.868	0.80
155_S	161_L	0.865	0.80
351_H	355_A	0.862	0.80
238_G	241_A	0.858	0.79
184_T	410_E	0.857	0.79
199_H	410_E	0.857	0.79
209_I	458_V	0.856	0.79
133_A	142_T	0.854	0.79
356_I	362_L	0.851	0.79
353_T	397_E	0.850	0.79
350_H	397_E	0.846	0.79
210_A	214_S	0.845	0.78
205_L	467_R	0.842	0.78
426_A	445_W	0.842	0.78
130_A	133_A	0.836	0.78
45_P	424_A	0.830	0.77
235_A	239_P	0.827	0.77
173_Y	218_Y	0.825	0.77
308_E	311_N	0.824	0.77
367_G	463_V	0.822	0.76
58_L	63_H	0.818	0.76
177_K	199_H	0.816	0.76
245_A	284_A	0.815	0.76
363_V	469_Y	0.810	0.75
434_Y	442_S	0.810	0.75
247_G	285_V	0.809	0.75
356_I	365_G	0.807	0.75
102_A	281_T	0.806	0.75
140_W	428_F	0.805	0.75
135_A	258_F	0.805	0.75
26_P	30_V	0.796	0.74
127_I	241_A	0.794	0.74
277_A	281_T	0.792	0.74
202_G	400_L	0.789	0.73
465_A	468_G	0.788	0.73
214_S	457_L	0.786	0.73
462_L	465_A	0.783	0.73
139_S	183_D	0.782	0.73
460_F	464_L	0.780	0.73
139_S	184_T	0.780	0.73
53_I	335_L	0.779	0.73
324_W	327_A	0.778	0.72
458_V	462_L	0.777	0.72
56_T	59_F	0.776	0.72
384_I	414_T	0.775	0.72
79_L	330_V	0.773	0.72
139_S	172_A	0.772	0.72
28_L	259_G	0.769	0.72
22_E	25_V	0.769	0.72
18_P	21_T	0.768	0.71
355_A	358_S	0.766	0.71
373_T	387_P	0.763	0.71
265_Y	273_A	0.759	0.71
289_S	457_L	0.758	0.70
97_A	293_A	0.758	0.70
86_I	105_I	0.757	0.70
239_P	242_G	0.757	0.70
256_V	273_A	0.756	0.70
157_L	222_G	0.755	0.70
102_A	400_L	0.754	0.70
267_A	313_L	0.753	0.70
22_E	59_F	0.750	0.70
94_G	275_V	0.749	0.70
185_T	188_A	0.749	0.70
66_Y	70_R	0.747	0.69
416_T	452_G	0.747	0.69
309_L	312_N	0.744	0.69
380_Q	425_G	0.742	0.69
98_T	293_A	0.742	0.69
176_D	410_E	0.738	0.68
53_I	331_A	0.737	0.68
160_P	448_Y	0.735	0.68
47_A	52_S	0.735	0.68
395_Y	405_L	0.734	0.68
169_V	449_Y	0.732	0.68
19_T	63_H	0.731	0.68
178_Q	184_T	0.729	0.67
298_L	324_W	0.727	0.67
216_L	308_E	0.726	0.67
441_I	444_W	0.725	0.67
138_S	381_Y	0.725	0.67
193_N	396_D	0.725	0.67
185_T	200_I	0.725	0.67
292_A	296_I	0.724	0.67
379_Q	417_G	0.722	0.67
384_I	409_V	0.719	0.66
316_T	321_G	0.719	0.66
95_L	271_L	0.718	0.66
88_I	92_I	0.717	0.66
142_T	172_A	0.717	0.66
60_A	260_L	0.716	0.66
26_P	56_T	0.715	0.66
259_G	262_F	0.715	0.66
430_T	445_W	0.715	0.66
367_G	371_I	0.714	0.66
379_Q	423_H	0.713	0.66
183_D	188_A	0.713	0.66
379_Q	424_A	0.712	0.66
32_V	243_S	0.712	0.66
205_L	209_I	0.709	0.65
380_Q	417_G	0.708	0.65
372_A	397_E	0.707	0.65
194_A	401_N	0.707	0.65
395_Y	408_A	0.706	0.65
447_P	450_F	0.706	0.65
138_S	380_Q	0.703	0.65
230_A	234_T	0.703	0.65
154_G	157_L	0.703	0.65
151_V	168_I	0.702	0.65
30_V	34_L	0.701	0.64
192_T	402_E	0.701	0.64
418_P	452_G	0.697	0.64
426_A	430_T	0.694	0.64
177_K	183_D	0.693	0.64
362_L	366_T	0.691	0.63
387_P	413_G	0.691	0.63
78_G	333_L	0.689	0.63
129_A	142_T	0.686	0.63
142_T	381_Y	0.685	0.63
319_I	327_A	0.685	0.63
131_V	255_V	0.685	0.63
199_H	203_M	0.683	0.62
120_V	123_P	0.681	0.62
221_L	225_I	0.681	0.62
33_S	48_P	0.677	0.62
282_T	293_A	0.676	0.62
212_G	289_S	0.676	0.62
186_N	190_A	0.675	0.62
385_V	420_F	0.673	0.61
186_N	196_L	0.673	0.61
173_Y	452_G	0.672	0.61
216_L	219_A	0.671	0.61
251_F	278_G	0.671	0.61
89_L	173_Y	0.669	0.61
93_Y	318_G	0.669	0.61
149_A	330_V	0.669	0.61
65_G	68_W	0.668	0.61
245_A	285_V	0.668	0.61
296_I	319_I	0.667	0.61
289_S	296_I	0.666	0.60
163_M	170_S	0.665	0.60
207_T	411_A	0.665	0.60
333_L	374_N	0.662	0.60
24_L	27_V	0.660	0.60
101_S	104_T	0.659	0.60
92_I	143_V	0.656	0.59
383_S	387_P	0.656	0.59
89_L	326_I	0.656	0.59
404_D	463_V	0.655	0.59
241_A	276_F	0.653	0.59
412_A	459_L	0.652	0.59
125_T	129_A	0.650	0.59
292_A	295_D	0.649	0.59
415_P	456_P	0.649	0.59
89_L	92_I	0.649	0.59
69_E	350_H	0.648	0.58
217_A	220_V	0.648	0.58
435_T	444_W	0.647	0.58
23_A	358_S	0.646	0.58
57_G	60_A	0.645	0.58
27_V	376_F	0.644	0.58
185_T	199_H	0.644	0.58
374_N	383_S	0.643	0.58
404_D	462_L	0.643	0.58
23_A	347_T	0.642	0.58
374_N	417_G	0.642	0.58
141_T	253_P	0.641	0.58
123_P	133_A	0.641	0.58
173_Y	416_T	0.639	0.57
49_L	89_L	0.639	0.57
18_P	22_E	0.638	0.57
188_A	199_H	0.637	0.57
202_G	470_D	0.636	0.57
261_A	278_G	0.635	0.57
106_P	244_Y	0.634	0.57
126_A	141_T	0.634	0.57
49_L	59_F	0.634	0.57
20_L	347_T	0.634	0.57
143_V	271_L	0.633	0.57
374_N	380_Q	0.630	0.56
63_H	66_Y	0.627	0.56
184_T	189_A	0.626	0.56
408_A	412_A	0.626	0.56
21_T	26_P	0.625	0.56
130_A	215_V	0.624	0.56
141_T	380_Q	0.624	0.56
86_I	330_V	0.624	0.56
333_L	388_S	0.623	0.55
26_P	344_V	0.622	0.55
141_T	381_Y	0.622	0.55
246_L	250_V	0.621	0.55
202_G	407_R	0.621	0.55
204_R	217_A	0.620	0.55
213_L	280_L	0.620	0.55
144_G	148_V	0.618	0.55
47_A	386_V	0.618	0.55
280_L	396_D	0.616	0.55
435_T	442_S	0.615	0.54
418_P	429_M	0.613	0.54
40_Y	218_Y	0.613	0.54
97_A	250_V	0.613	0.54
242_G	276_F	0.613	0.54
170_S	449_Y	0.611	0.54
220_V	235_A	0.611	0.54
370_A	387_P	0.610	0.54
228_G	256_V	0.609	0.54
218_Y	451_F	0.608	0.54
311_N	314_L	0.608	0.54
372_A	376_F	0.608	0.54
266_P	269_P	0.607	0.54
133_A	294_W	0.606	0.53
457_L	460_F	0.605	0.53
108_L	183_D	0.604	0.53
353_T	356_I	0.604	0.53
120_V	124_V	0.602	0.53
441_I	446_A	0.602	0.53
253_P	261_A	0.601	0.53
376_F	418_P	0.601	0.53
122_L	154_G	0.601	0.53
151_V	432_A	0.600	0.53
117_T	124_V	0.598	0.52
101_S	288_A	0.597	0.52
126_A	253_P	0.597	0.52
134_F	183_D	0.596	0.52
87_L	105_I	0.595	0.52
72_S	105_I	0.593	0.52
156_G	236_I	0.592	0.52
139_S	142_T	0.591	0.52
85_A	141_T	0.590	0.51
218_Y	450_F	0.589	0.51
140_W	417_G	0.589	0.51
220_V	243_S	0.587	0.51
60_A	365_G	0.587	0.51
378_A	417_G	0.585	0.51
133_A	180_P	0.585	0.51
169_V	423_H	0.585	0.51
112_G	149_A	0.584	0.51
150_F	427_V	0.583	0.51
194_A	376_F	0.582	0.51
176_D	182_S	0.581	0.50
339_L	342_T	0.580	0.50
291_T	450_F	0.580	0.50
173_Y	418_P	0.578	0.50
260_L	270_S	0.577	0.50
221_L	448_Y	0.577	0.50
404_D	408_A	0.577	0.50
332_A	336_G	0.575	0.50
207_T	414_T	0.575	0.50
220_V	224_L	0.574	0.50
57_G	71_V	0.573	0.49
174_A	466_G	0.572	0.49
329_V	382_M	0.572	0.49
110_Y	114_G	0.571	0.49
400_L	405_L	0.571	0.49
195_D	201_N	0.571	0.49
53_I	452_G	0.570	0.49
206_G	459_L	0.568	0.49
239_P	310_V	0.564	0.48
323_A	326_I	0.563	0.48
366_T	408_A	0.563	0.48
50_L	331_A	0.562	0.48
141_T	382_M	0.562	0.48
121_F	161_L	0.562	0.48
430_T	435_T	0.561	0.48
140_W	424_A	0.561	0.48
380_Q	451_F	0.560	0.48
154_G	159_I	0.559	0.48
211_F	451_F	0.559	0.48
105_I	332_A	0.558	0.48
105_I	274_G	0.557	0.48
102_A	251_F	0.557	0.48
142_T	156_G	0.556	0.47
290_F	299_N	0.555	0.47
64_L	89_L	0.555	0.47
186_N	387_P	0.554	0.47
53_I	57_G	0.553	0.47
144_G	432_A	0.553	0.47
66_Y	341_R	0.552	0.47
153_I	156_G	0.551	0.47
196_L	427_V	0.550	0.47
273_A	277_A	0.550	0.47
130_A	294_W	0.549	0.47
363_V	408_A	0.549	0.47
281_T	284_A	0.548	0.46
53_I	75_A	0.548	0.46
274_G	385_V	0.546	0.46
367_G	408_A	0.546	0.46
361_S	464_L	0.545	0.46
190_A	456_P	0.545	0.46
356_I	398_Y	0.545	0.46
31_V	373_T	0.545	0.46
28_L	31_V	0.544	0.46
199_H	414_T	0.543	0.46
38_S	45_P	0.542	0.46
89_L	139_S	0.539	0.45
116_L	128_L	0.539	0.45
287_G	319_I	0.539	0.45
121_F	157_L	0.539	0.45
79_L	222_G	0.539	0.45
126_A	214_S	0.538	0.45
116_L	139_S	0.538	0.45
392_R	402_E	0.537	0.45
122_L	167_A	0.535	0.45
293_A	296_I	0.533	0.45
123_P	160_P	0.533	0.45
104_T	191_V	0.533	0.45
164_T	294_W	0.533	0.45
353_T	394_L	0.532	0.45
218_Y	221_L	0.532	0.45
44_A	324_W	0.532	0.45
41_L	290_F	0.530	0.44
127_I	453_I	0.529	0.44
435_T	446_A	0.528	0.44
154_G	160_P	0.528	0.44
245_A	249_L	0.527	0.44
74_A	328_V	0.527	0.44
85_A	374_N	0.526	0.44
123_P	419_F	0.525	0.44
144_G	428_F	0.525	0.44
153_I	244_Y	0.525	0.44
216_L	359_P	0.524	0.44
258_F	262_F	0.524	0.44
89_L	190_A	0.524	0.44
256_V	260_L	0.523	0.43
311_N	328_V	0.523	0.43
465_A	469_Y	0.522	0.43
369_A	406_S	0.522	0.43
37_G	43_L	0.522	0.43
244_Y	286_Q	0.522	0.43
47_A	61_R	0.521	0.43
140_W	455_S	0.521	0.43
462_L	467_R	0.521	0.43
375_A	416_T	0.521	0.43
364_A	367_G	0.518	0.43
178_Q	200_I	0.518	0.43
25_V	246_L	0.518	0.43
34_L	38_S	0.518	0.43
26_P	250_V	0.517	0.43
254_L	271_L	0.517	0.43
177_K	185_T	0.517	0.43
274_G	413_G	0.516	0.43
238_G	242_G	0.516	0.43
123_P	382_M	0.516	0.43
234_T	326_I	0.515	0.42
352_L	369_A	0.515	0.42
151_V	160_P	0.515	0.42
189_A	192_T	0.514	0.42
149_A	366_T	0.514	0.42
121_F	165_A	0.514	0.42
60_A	344_V	0.513	0.42
178_Q	410_E	0.513	0.42
374_N	381_Y	0.512	0.42
76_L	83_L	0.512	0.42
174_A	178_Q	0.512	0.42
65_G	212_G	0.512	0.42
276_F	280_L	0.512	0.42
71_V	342_T	0.511	0.42
79_L	269_P	0.511	0.42
167_A	210_A	0.511	0.42
107_G	466_G	0.511	0.42
327_A	390_S	0.511	0.42
214_S	450_F	0.510	0.42
363_V	366_T	0.510	0.42
400_L	470_D	0.509	0.42
50_L	333_L	0.507	0.42
150_F	193_N	0.506	0.41
203_M	348_L	0.506	0.41
30_V	451_F	0.506	0.41
166_G	386_V	0.506	0.41
26_P	52_S	0.505	0.41
58_L	61_R	0.505	0.41
250_V	254_L	0.505	0.41
61_R	71_V	0.504	0.41
105_I	109_M	0.503	0.41
112_G	180_P	0.500	0.41
442_S	447_P	0.500	0.41
108_L	192_T	0.500	0.41

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4f35D	2	0.8208	99.9	0.812	Contact Map
4r1iA	2	0.8921	99.9	0.833	Contact Map
4r0cA	3	0.4582	99.7	0.865	Contact Map
3qe7A	2	0.7169	86	0.964	Contact Map
4pd6A	3	0.4521	75.1	0.968	Contact Map
2kncA	1	0.1059	24.7	0.977	Contact Map
3zuxA	1	0.6008	18.6	0.978	Contact Map
2l9xA	1	0.0591	17.5	0.978	Contact Map
4czbA	2	0.666	16.6	0.979	Contact Map
4tphA	2	0.778	16.4	0.979	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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