Q9HNF1 - HALSA - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

Q9HNF1 - Cell division inhibitor

UniProt:	Q9HNF1	Sequences: MSGRVFAVASGKGGVGKTTTAVNVAAVMAEADRSVVLVDADLGMANVDHVVACDESATATLHDVLADDAALTDATAAAPAGFDVIVGGTTITDFGRADPSALPDVAATLRDRYDCVIVDTGGGLSHDTTVPLGLADETVLVSTRQTAALANTAKTRALVERVGGHVAGAVVTRVTDDAGGADAGHGDAAAATLQTDILGLIPEDSRVADSERAGTPLVSLAPESPAAQAYRELAYTLLDEPLPVSFRDGDASGDAASGLMAASAPSGAPTDDGSGAGAATGDDQTRDASILWRLTGGLLGSNGKR	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	305 (237)
Sequences:	13601 (8556)
Seq/√Len:	555.8

ECOLI - MRP MIND BCSQ
BACSU - YLXH SOJ MIND SALA YWQD YVEL
HALSA - Q9HNF1 Q9HQY5 Q9HHU2 Q9HHZ7 Q9HQJ7 O54573 O51969 Q9HHL5 O51991
SULSO - Q97ZW4 Q981B3 Q97VX7 Q97WA2 Q97YM8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
83_D	113_Y	4.246	1.00
202_P	229_A	4.022	1.00
21_A	117_I	3.699	1.00
31_A	235_Y	3.357	1.00
28_M	115_C	2.986	1.00
20_T	230_Y	2.985	1.00
7_A	135_A	2.936	1.00
216_P	219_S	2.891	1.00
33_R	115_C	2.888	1.00
4_R	137_E	2.527	1.00
173_R	203_E	2.522	1.00
36_V	113_Y	2.498	1.00
178_A	181_A	2.494	1.00
22_V	47_V	2.259	1.00
50_V	147_A	2.255	1.00
143_T	173_R	2.245	1.00
77_A	83_D	2.240	1.00
37_L	47_V	2.234	1.00
30_E	231_R	2.228	1.00
27_V	234_A	2.175	1.00
21_A	37_L	2.155	1.00
20_T	170_V	2.130	1.00
8_V	24_V	2.119	1.00
27_V	218_V	2.103	1.00
170_V	233_L	2.083	1.00
206_R	209_D	2.065	1.00
25_A	37_L	2.030	1.00
199_G	236_T	1.972	1.00
31_A	231_R	1.916	1.00
34_S	114_D	1.897	1.00
137_E	167_A	1.742	1.00
187_D	191_A	1.723	1.00
33_R	238_L	1.710	1.00
175_T	203_E	1.692	1.00
70_A	73_D	1.676	1.00
25_A	117_I	1.662	1.00
49_H	150_A	1.640	1.00
40_A	131_P	1.633	1.00
199_G	233_L	1.626	1.00
72_T	112_R	1.623	1.00
60_T	63_D	1.610	1.00
22_V	50_V	1.597	1.00
28_M	117_I	1.595	1.00
24_V	237_L	1.590	1.00
171_V	186_G	1.583	1.00
8_V	139_V	1.558	1.00
188_A	192_T	1.557	1.00
40_A	118_V	1.557	1.00
7_A	120_T	1.542	1.00
24_V	234_A	1.514	1.00
204_D	226_A	1.512	1.00
198_L	236_T	1.510	1.00
29_A	82_F	1.503	1.00
189_A	193_L	1.481	1.00
33_R	114_D	1.476	1.00
186_G	190_A	1.461	1.00
8_V	21_A	1.415	1.00
40_A	61_L	1.395	1.00
25_A	47_V	1.380	1.00
139_V	170_V	1.347	1.00
144_R	171_V	1.336	1.00
138_T	159_V	1.334	1.00
16_G	172_T	1.333	1.00
5_V	118_V	1.332	1.00
206_R	221_A	1.330	1.00
31_A	238_L	1.329	1.00
9_A	155_T	1.328	1.00
20_T	172_T	1.319	1.00
215_T	220_L	1.318	1.00
196_D	240_E	1.307	1.00
224_S	227_A	1.304	1.00
188_A	191_A	1.298	1.00
46_N	151_N	1.264	1.00
137_E	168_G	1.261	1.00
205_S	209_D	1.261	1.00
174_V	200_L	1.256	1.00
51_V	82_F	1.246	1.00
20_T	24_V	1.243	1.00
4_R	136_D	1.242	1.00
22_V	51_V	1.217	1.00
207_V	226_A	1.216	1.00
201_I	226_A	1.202	1.00
180_G	183_A	1.200	1.00
102_L	105_V	1.199	1.00
228_Q	231_R	1.192	1.00
59_A	63_D	1.165	1.00
145_Q	148_A	1.149	1.00
29_A	81_G	1.141	1.00
27_V	231_R	1.139	1.00
204_D	224_S	1.136	1.00
225_P	228_Q	1.129	1.00
69_A	73_D	1.126	1.00
18_T	47_V	1.123	1.00
9_A	120_T	1.120	1.00
18_T	50_V	1.113	1.00
120_T	131_P	1.106	1.00
89_T	154_K	1.105	1.00
8_V	20_T	1.093	1.00
71_L	85_I	1.091	1.00
80_A	83_D	1.090	1.00
36_V	75_T	1.090	1.00
233_L	237_L	1.072	1.00
103_P	107_A	1.067	1.00
61_L	64_V	1.062	1.00
28_M	234_A	1.046	1.00
232_E	236_T	1.042	1.00
172_T	230_Y	1.028	1.00
176_D	185_H	1.023	1.00
181_A	185_H	1.008	1.00
46_N	147_A	1.006	1.00
64_V	74_A	1.000	1.00
28_M	35_V	0.996	1.00
235_Y	239_D	0.996	1.00
201_I	229_A	0.992	1.00
231_R	235_Y	0.989	1.00
105_V	108_T	0.988	1.00
6_F	115_C	0.987	1.00
115_C	238_L	0.984	1.00
95_G	125_S	0.983	1.00
26_A	30_E	0.980	1.00
34_S	112_R	0.978	1.00
147_A	211_E	0.973	1.00
27_V	31_A	0.969	1.00
215_T	219_S	0.965	1.00
74_A	85_I	0.964	1.00
53_C	84_V	0.961	1.00
23_N	26_A	0.957	1.00
110_R	136_D	0.948	1.00
232_E	235_Y	0.946	1.00
25_A	82_F	0.945	1.00
6_F	237_L	0.944	1.00
222_P	227_A	0.943	1.00
38_V	116_V	0.942	1.00
218_V	231_R	0.939	1.00
62_H	66_A	0.938	1.00
145_Q	208_A	0.935	1.00
229_A	232_E	0.931	1.00
8_V	117_I	0.925	1.00
30_E	219_S	0.924	1.00
3_G	110_R	0.911	1.00
197_I	200_L	0.900	1.00
59_A	69_A	0.890	1.00
5_V	110_R	0.885	1.00
176_D	179_G	0.885	1.00
23_N	218_V	0.882	1.00
204_D	225_P	0.879	1.00
64_V	105_V	0.877	1.00
142_S	186_G	0.874	1.00
30_E	218_V	0.870	1.00
9_A	128_T	0.864	1.00
187_D	190_A	0.862	1.00
42_L	127_D	0.862	1.00
115_C	241_P	0.861	1.00
51_V	78_A	0.859	1.00
6_F	137_E	0.858	1.00
213_A	220_L	0.853	1.00
98_D	101_A	0.852	1.00
24_V	233_L	0.851	1.00
45_A	87_G	0.848	1.00
38_V	118_V	0.847	1.00
141_V	172_T	0.847	1.00
78_A	83_D	0.842	1.00
104_D	108_T	0.838	1.00
96_R	99_P	0.836	1.00
5_V	136_D	0.835	1.00
217_L	227_A	0.832	1.00
186_G	192_T	0.829	1.00
105_V	109_L	0.824	1.00
144_R	174_V	0.824	1.00
19_T	207_V	0.822	1.00
40_A	102_L	0.818	1.00
64_V	85_I	0.818	1.00
187_D	200_L	0.811	1.00
236_T	240_E	0.810	1.00
17_K	122_G	0.802	1.00
27_V	230_Y	0.802	1.00
44_M	122_G	0.801	1.00
11_G	158_L	0.799	1.00
23_N	216_P	0.799	1.00
5_V	116_V	0.792	1.00
36_V	116_V	0.791	1.00
157_A	160_E	0.791	1.00
72_T	108_T	0.788	1.00
175_T	184_G	0.786	1.00
15_V	148_A	0.784	1.00
35_V	114_D	0.781	1.00
90_T	157_A	0.780	1.00
69_A	74_A	0.779	1.00
12_K	17_K	0.770	1.00
98_D	127_D	0.765	1.00
160_E	163_G	0.765	1.00
62_H	97_A	0.763	1.00
19_T	211_E	0.757	1.00
209_D	213_A	0.757	1.00
107_A	110_R	0.756	1.00
45_A	88_G	0.756	1.00
40_A	127_D	0.756	1.00
140_L	152_T	0.754	1.00
223_E	228_Q	0.754	1.00
96_R	126_H	0.751	1.00
129_T	158_L	0.751	1.00
167_A	241_P	0.749	1.00
131_P	135_A	0.748	1.00
153_A	192_T	0.746	1.00
70_A	108_T	0.738	1.00
171_V	174_V	0.737	1.00
75_T	83_D	0.737	1.00
143_T	148_A	0.737	1.00
18_T	46_N	0.736	1.00
180_G	185_H	0.732	1.00
221_A	224_S	0.728	1.00
226_A	229_A	0.723	1.00
26_A	218_V	0.720	1.00
75_T	113_Y	0.718	1.00
10_S	15_V	0.715	1.00
37_L	51_V	0.714	1.00
202_P	225_P	0.712	1.00
63_D	68_D	0.708	1.00
73_D	76_A	0.707	1.00
225_P	229_A	0.706	1.00
27_V	227_A	0.705	1.00
186_G	200_L	0.704	1.00
58_T	62_H	0.703	1.00
117_I	237_L	0.702	1.00
20_T	141_V	0.700	1.00
45_A	48_D	0.698	1.00
125_S	128_T	0.698	1.00
137_E	241_P	0.696	1.00
218_V	227_A	0.696	1.00
78_A	84_V	0.695	1.00
4_R	167_A	0.694	1.00
144_R	181_A	0.689	1.00
38_V	106_A	0.687	1.00
190_A	200_L	0.686	1.00
177_D	181_A	0.685	1.00
103_P	134_L	0.685	1.00
36_V	109_L	0.679	1.00
70_A	75_T	0.678	1.00
86_V	89_T	0.678	1.00
49_H	147_A	0.672	1.00
137_E	166_V	0.670	1.00
35_V	82_F	0.670	1.00
140_L	156_R	0.669	1.00
113_Y	116_V	0.669	1.00
3_G	116_V	0.669	1.00
120_T	128_T	0.668	1.00
171_V	189_A	0.668	1.00
83_D	86_V	0.666	1.00
35_V	117_I	0.664	1.00
210_S	217_L	0.663	1.00
153_A	157_A	0.662	1.00
49_H	146_T	0.657	1.00
142_S	169_A	0.655	1.00
4_R	33_R	0.654	1.00
26_A	216_P	0.648	1.00
209_D	220_L	0.648	1.00
217_L	226_A	0.647	1.00
94_F	98_D	0.647	1.00
32_D	81_G	0.646	1.00
228_Q	232_E	0.642	1.00
9_A	132_L	0.639	1.00
5_V	135_A	0.633	1.00
178_A	205_S	0.633	1.00
227_A	231_R	0.632	1.00
20_T	201_I	0.630	1.00
97_A	100_S	0.629	1.00
38_V	85_I	0.627	1.00
174_V	186_G	0.626	1.00
26_A	219_S	0.625	1.00
60_T	88_G	0.624	1.00
64_V	67_D	0.624	1.00
146_T	150_A	0.623	1.00
46_N	150_A	0.622	1.00
23_N	230_Y	0.621	1.00
22_V	37_L	0.618	1.00
3_G	34_S	0.615	1.00
23_N	217_L	0.614	1.00
63_D	67_D	0.612	1.00
205_S	208_A	0.611	1.00
79_P	83_D	0.609	1.00
154_K	157_A	0.609	1.00
48_D	82_F	0.606	1.00
34_S	81_G	0.606	1.00
139_V	237_L	0.600	1.00
171_V	197_I	0.600	1.00
12_K	15_V	0.599	1.00
146_T	212_R	0.597	1.00
12_K	147_A	0.594	1.00
3_G	112_R	0.593	1.00
7_A	138_T	0.591	1.00
78_A	81_G	0.590	1.00
191_A	194_Q	0.589	1.00
190_A	198_L	0.588	1.00
61_L	85_I	0.585	1.00
132_L	138_T	0.583	1.00
59_A	73_D	0.582	1.00
26_A	29_A	0.577	0.99
201_I	233_L	0.576	0.99
27_V	30_E	0.573	0.99
21_A	47_V	0.573	0.99
73_D	78_A	0.572	0.99
48_D	86_V	0.571	0.99
95_G	98_D	0.569	0.99
194_Q	197_I	0.569	0.99
140_L	166_V	0.568	0.99
6_F	167_A	0.567	0.99
28_M	238_L	0.567	0.99
234_A	238_L	0.565	0.99
35_V	115_C	0.562	0.99
187_D	197_I	0.558	0.99
75_T	78_A	0.557	0.99
11_G	155_T	0.557	0.99
34_S	113_Y	0.556	0.99
118_V	131_P	0.556	0.99
210_S	220_L	0.554	0.99
46_N	148_A	0.553	0.99
7_A	131_P	0.550	0.99
58_T	63_D	0.547	0.99
210_S	216_P	0.547	0.99
168_G	196_D	0.546	0.99
175_T	205_S	0.546	0.99
71_L	109_L	0.545	0.99
171_V	200_L	0.541	0.99
66_A	97_A	0.535	0.99
76_A	86_V	0.535	0.99
153_A	193_L	0.535	0.99
59_A	62_H	0.533	0.99
106_A	134_L	0.532	0.99
219_S	222_P	0.532	0.99
101_A	105_V	0.531	0.99
132_L	162_V	0.530	0.99
189_A	192_T	0.529	0.99
110_R	116_V	0.529	0.99
34_S	83_D	0.528	0.99
59_A	74_A	0.528	0.99
31_A	234_A	0.526	0.99
36_V	83_D	0.526	0.99
79_P	82_F	0.525	0.99
207_V	217_L	0.524	0.99
10_S	17_K	0.523	0.99
208_A	211_E	0.522	0.99
180_G	208_A	0.519	0.99
5_V	106_A	0.518	0.99
24_V	170_V	0.518	0.99
177_D	180_G	0.518	0.99
70_A	74_A	0.514	0.99
168_G	198_L	0.514	0.99
26_A	82_F	0.513	0.99
207_V	210_S	0.509	0.99
97_A	101_A	0.507	0.99
201_I	230_Y	0.506	0.99
143_T	208_A	0.505	0.99
217_L	220_L	0.505	0.99
181_A	184_G	0.503	0.99
207_V	211_E	0.500	0.99
138_T	166_V	0.500	0.99

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1g3qA	1	0.7738	100	0.323	Contact Map
1hyqA	1	0.7607	100	0.33	Contact Map
4pfsA	1	0.7607	100	0.333	Contact Map
3ea0A	2	0.7639	100	0.341	Contact Map
4rz3A	2	0.7672	100	0.347	Contact Map
3pg5A	2	0.7016	100	0.352	Contact Map
3q9lA	2	0.8033	100	0.352	Contact Map
4v03A	2	0.7607	100	0.355	Contact Map
1wcv1	2	0.7639	100	0.357	Contact Map
3ez9A	2	0.6721	100	0.38	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.009 seconds.