VATE - HALSA - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

VATE - V-type ATP synthase subunit E

UniProt:	Q9HNE0	Sequences: MSLETVVEDIRDEARERAKEIRADADERADEIVAEAEADADDIIADAEAEVTAEIDQEREQQLSSAELEAKQMRLEARRDALQSVRSAVEDRIVALDGDEREELTRELLDAASTEFDGADTVRVFGRADDEALISEILDDYDGYEYAGEYDCLGGVVVESDASRIRVNNTFDSILADAWENNLKAISARLFDEEQ	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	195 (184)
Sequences:	758 (545)
Seq/√Len:	40.2

HALSA - VATE
SULSO - VATE

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
24_D	28_R	4.260	1.00
137_I	141_Y	3.902	1.00
126_G	134_I	3.760	1.00
28_R	31_E	3.378	1.00
106_R	140_D	3.246	1.00
102_E	136_E	3.234	1.00
77_A	80_D	3.039	1.00
37_E	41_D	2.940	1.00
109_L	124_V	2.910	1.00
97_D	100_E	2.734	1.00
17_R	20_E	2.569	1.00
22_R	26_D	2.432	1.00
92_R	95_A	2.416	1.00
112_A	158_V	2.357	1.00
88_A	91_D	2.226	1.00
30_D	34_A	2.170	0.99
131_E	135_S	2.136	0.99
33_V	37_E	2.049	0.99
14_A	18_A	1.979	0.99
8_E	11_R	1.964	0.99
26_D	30_D	1.884	0.98
173_S	176_A	1.876	0.98
23_A	27_E	1.797	0.98
101_R	171_F	1.772	0.98
152_C	172_D	1.671	0.96
91_D	98_G	1.667	0.96
103_E	106_R	1.649	0.96
152_C	170_T	1.624	0.96
143_G	146_Y	1.606	0.96
88_A	92_R	1.567	0.95
184_K	187_S	1.542	0.94
93_I	133_L	1.524	0.94
138_L	142_D	1.516	0.94
128_A	132_A	1.470	0.93
59_R	62_Q	1.456	0.93
104_L	108_L	1.454	0.92
185_A	188_A	1.396	0.91
101_R	130_D	1.394	0.91
124_V	156_V	1.359	0.90
83_Q	87_S	1.353	0.89
35_E	39_D	1.349	0.89
70_A	169_N	1.345	0.89
71_K	174_I	1.320	0.88
121_T	161_D	1.318	0.88
154_G	169_N	1.281	0.87
143_G	158_V	1.264	0.86
66_A	85_V	1.263	0.86
125_F	159_E	1.253	0.85
75_L	192_D	1.247	0.85
15_R	19_K	1.231	0.84
97_D	129_D	1.229	0.84
82_L	86_R	1.228	0.84
168_N	173_S	1.225	0.84
169_N	174_I	1.219	0.84
78_R	81_A	1.219	0.84
55_I	62_Q	1.214	0.84
123_R	147_A	1.196	0.83
123_R	145_E	1.187	0.82
78_R	142_D	1.175	0.82
87_S	128_A	1.173	0.81
87_S	91_D	1.170	0.81
170_T	181_N	1.160	0.81
20_E	24_D	1.158	0.81
23_A	40_A	1.153	0.80
12_D	41_D	1.140	0.80
128_A	131_E	1.137	0.79
98_G	103_E	1.137	0.79
106_R	110_D	1.135	0.79
85_V	179_W	1.128	0.79
16_E	19_K	1.126	0.79
65_S	68_L	1.125	0.79
93_I	145_E	1.122	0.78
131_E	146_Y	1.118	0.78
25_A	29_A	1.105	0.77
121_T	160_S	1.105	0.77
66_A	182_N	1.103	0.77
134_I	142_D	1.096	0.77
85_V	182_N	1.094	0.77
132_A	135_S	1.086	0.76
20_E	31_E	1.080	0.76
26_D	29_A	1.077	0.76
43_I	47_A	1.076	0.75
16_E	30_D	1.075	0.75
77_A	81_A	1.064	0.75
44_I	48_E	1.063	0.75
31_E	35_E	1.061	0.74
118_G	122_V	1.049	0.74
84_S	87_S	1.046	0.73
19_K	35_E	1.045	0.73
103_E	107_E	1.038	0.73
17_R	21_I	1.004	0.70
61_Q	190_L	1.002	0.70
135_S	146_Y	1.001	0.70
12_D	15_R	1.001	0.70
69_E	80_D	0.994	0.69
138_L	141_Y	0.988	0.69
182_N	185_A	0.978	0.68
86_R	179_W	0.976	0.68
10_I	14_A	0.976	0.68
145_E	148_G	0.974	0.68
131_E	144_Y	0.971	0.68
30_D	33_V	0.969	0.67
34_A	38_A	0.966	0.67
84_S	89_V	0.965	0.67
34_A	49_A	0.958	0.67
98_G	129_D	0.949	0.66
22_R	33_V	0.945	0.65
131_E	136_E	0.942	0.65
15_R	18_A	0.936	0.65
116_F	174_I	0.931	0.64
84_S	88_A	0.923	0.64
38_A	41_D	0.922	0.64
24_D	31_E	0.921	0.63
92_R	120_D	0.913	0.63
20_E	35_E	0.907	0.62
120_D	161_D	0.904	0.62
20_E	27_E	0.903	0.62
39_D	45_A	0.901	0.62
13_E	16_E	0.899	0.62
34_A	37_E	0.895	0.61
25_A	28_R	0.893	0.61
49_A	52_T	0.889	0.61
52_T	56_D	0.885	0.60
112_A	167_V	0.878	0.60
22_R	50_E	0.865	0.59
78_R	82_L	0.854	0.58
68_L	171_F	0.844	0.57
95_A	132_A	0.843	0.57
168_N	179_W	0.839	0.56
110_D	141_Y	0.839	0.56
63_L	81_A	0.822	0.55
68_L	78_R	0.817	0.54
69_E	72_Q	0.816	0.54
109_L	156_V	0.813	0.54
128_A	150_Y	0.812	0.54
8_E	15_R	0.812	0.54
131_E	173_S	0.808	0.53
125_F	145_E	0.808	0.53
26_D	46_D	0.807	0.53
46_D	50_E	0.806	0.53
10_I	75_L	0.805	0.53
85_V	131_E	0.804	0.53
13_E	52_T	0.798	0.52
44_I	62_Q	0.794	0.52
76_E	181_N	0.792	0.52
38_A	115_E	0.789	0.52
109_L	134_I	0.785	0.51
9_D	13_E	0.778	0.51
126_G	156_V	0.777	0.51
71_K	79_R	0.768	0.50
18_A	33_V	0.767	0.50
43_I	46_D	0.767	0.50
33_V	52_T	0.766	0.50
19_K	26_D	0.765	0.49
44_I	187_S	0.764	0.49
19_K	22_R	0.762	0.49
131_E	161_D	0.759	0.49
113_S	129_D	0.755	0.49
39_D	171_F	0.752	0.48
20_E	28_R	0.742	0.47
95_A	99_D	0.737	0.47
81_A	190_L	0.736	0.47
123_R	152_C	0.722	0.46
114_T	165_I	0.721	0.45
98_G	132_A	0.719	0.45
16_E	52_T	0.714	0.45
17_R	174_I	0.714	0.45
142_D	183_L	0.709	0.44
8_E	73_M	0.707	0.44
10_I	66_A	0.704	0.44
31_E	49_A	0.702	0.44
23_A	34_A	0.700	0.44
156_V	174_I	0.692	0.43
123_R	159_E	0.692	0.43
112_A	145_E	0.691	0.43
144_Y	185_A	0.686	0.42
10_I	146_Y	0.684	0.42
134_I	137_I	0.684	0.42
99_D	132_A	0.681	0.42
9_D	12_D	0.677	0.41
139_D	186_I	0.671	0.41
73_M	76_E	0.670	0.41
45_A	49_A	0.670	0.41
91_D	129_D	0.669	0.41
31_E	62_Q	0.669	0.41
169_N	184_K	0.669	0.41
71_K	150_Y	0.669	0.41
15_R	129_D	0.668	0.41
44_I	55_I	0.663	0.40
16_E	45_A	0.663	0.40
147_A	166_R	0.661	0.40
89_V	163_S	0.655	0.40
81_A	84_S	0.653	0.39
24_D	48_E	0.649	0.39
111_A	115_E	0.647	0.39
9_D	14_A	0.644	0.39
74_R	92_R	0.641	0.38
23_A	39_D	0.640	0.38
112_A	116_F	0.637	0.38
21_I	28_R	0.636	0.38
105_T	170_T	0.632	0.38
51_V	56_D	0.630	0.37
158_V	161_D	0.629	0.37
86_R	90_E	0.626	0.37
95_A	128_A	0.626	0.37
51_V	55_I	0.622	0.37
121_T	143_G	0.619	0.36
47_A	71_K	0.618	0.36
149_E	170_T	0.615	0.36
23_A	26_D	0.612	0.36
83_Q	164_R	0.612	0.36
126_G	167_V	0.612	0.36
9_D	55_I	0.611	0.36
10_I	23_A	0.611	0.36
14_A	41_D	0.611	0.36
157_V	168_N	0.609	0.36
147_A	163_S	0.609	0.36
18_A	181_N	0.608	0.35
90_E	179_W	0.608	0.35
40_A	61_Q	0.605	0.35
53_A	103_E	0.602	0.35
54_E	63_L	0.597	0.35
158_V	182_N	0.597	0.35
9_D	15_R	0.596	0.34
45_A	56_D	0.592	0.34
99_D	156_V	0.590	0.34
131_E	138_L	0.589	0.34
17_R	40_A	0.588	0.34
22_R	183_L	0.586	0.34
121_T	162_A	0.582	0.33
149_E	152_C	0.581	0.33
65_S	77_A	0.581	0.33
70_A	159_E	0.566	0.32
100_E	107_E	0.566	0.32
84_S	162_A	0.562	0.32
39_D	55_I	0.560	0.32
125_F	128_A	0.560	0.32
133_L	158_V	0.558	0.31
110_D	128_A	0.558	0.31
84_S	94_V	0.554	0.31
117_D	171_F	0.553	0.31
41_D	45_A	0.550	0.31
84_S	135_S	0.550	0.31
99_D	131_E	0.549	0.31
92_R	104_L	0.548	0.31
72_Q	154_G	0.546	0.30
126_G	130_D	0.543	0.30
35_E	38_A	0.540	0.30
9_D	179_W	0.538	0.30
62_Q	109_L	0.538	0.30
159_E	187_S	0.536	0.30
108_L	114_T	0.533	0.29
160_S	182_N	0.531	0.29
56_D	61_Q	0.530	0.29
77_A	152_C	0.528	0.29
68_L	72_Q	0.527	0.29
118_G	190_L	0.525	0.29
111_A	169_N	0.523	0.29
91_D	95_A	0.522	0.29
14_A	40_A	0.521	0.29
123_R	160_S	0.519	0.28
61_Q	152_C	0.516	0.28
11_R	14_A	0.514	0.28
125_F	148_G	0.512	0.28
168_N	186_I	0.512	0.28
98_G	147_A	0.511	0.28
21_I	31_E	0.511	0.28
113_S	122_V	0.509	0.28
48_E	71_K	0.509	0.28
151_D	166_R	0.506	0.27
104_L	162_A	0.503	0.27
63_L	86_R	0.503	0.27
67_E	158_V	0.502	0.27
134_I	138_L	0.502	0.27
103_E	109_L	0.501	0.27
147_A	150_Y	0.500	0.27

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4efaE	1	0.9795	100	0.295	Contact Map
2dm9A	2	0.5744	100	0.317	Contact Map
3v6iA	1	0.9538	100	0.325	Contact Map
3lg8A	1	0.4821	99.9	0.544	Contact Map
2kk7A	1	0.241	97.7	0.827	Contact Map
1l2pA	1	0.3128	94.3	0.876	Contact Map
4efaG	1	0.4769	78.7	0.906	Contact Map
2wssS	1	0.7231	76.6	0.908	Contact Map
3v6iB	1	0.4667	67.5	0.914	Contact Map
2k6iA	1	0.2256	27.4	0.933	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0073 seconds.