VATI - HALSA - GREMLIN Contacts

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VATI - V-type ATP synthase subunit I

UniProt:	Q9HND8	Sequences: MLRPEQMSKVSVAGSTHVLTPVIEAVHDAELVHLSDYDGGIDGFDNGDPMTGADEAAEKLVTVRSLKSLLDVSEGDAGPTRIVTDDALDTELESIRVEATDLDDRRSELTDDLRAVIERIDAAEPFADLGIDLDLLSGYDSLQVAVGTGDQSAIDAALAASDRISAFETFTGQDTIGVFAYPAADDDAALDDALVGVPFTRLDVPDADGSPEQYVSELRERRDTIQAEIEDVDDELAAFRDEHAGFLLAAEERLAIDVQKSEAPLQFASTSHAFVAEGWLPTSEYDAFTDAIESAVGDHVLVEELERADYKPTGHDQHVPADDGADAATDGGTTASFDETDSPPVIQDNPGPVSSFESLTEVINRPQYTEIDPTVVLFLTFPAFYGFMIGDLGYGVLYALLGFWLSRSFDSEMISKLGGVAMWAGGFTALFGVLYGEVFGLHLVTEYLWHGALGLADAPLKKGLHVSAFAELWLAASLVFGIAHLAIGYVFGFVNESRSHGLKDAALESGGQLLLMAGVGVWLFSTHMQSGGGPRPELLYSVVALPPIVGKAGLAAAVVGLVLVTLGEGAAGFLESPTYALVNTVSYTRIAAVLLAKAGMAYVVNLLVFGAYETHLEHPETIDYMFGLFSTTIEHETHFMLFSGEAHGEVLFPGLMHMGAAGILIGVLVLLVGHALVLALGVTSAGLQALRLEYVEFFNKFYEGGGEKYNPFGYTRNYTTED	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	722 (574)
Sequences:	1363 (1031)
Seq/√Len:	43.0

HALSA - VATI
SULSO - VATI

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
501_G	504_D	7.299	1.00
392_L	429_A	6.150	1.00
8_S	282_T	5.652	1.00
105_R	228_E	4.893	1.00
430_L	434_L	4.527	1.00
109_L	225_I	4.391	1.00
484_H	587_Y	4.210	1.00
392_L	433_V	4.201	1.00
112_D	221_R	4.094	1.00
399_A	425_G	4.082	1.00
113_L	222_R	3.921	1.00
116_V	218_L	3.669	1.00
396_V	429_A	3.440	1.00
404_W	408_S	3.379	1.00
393_G	439_F	3.314	1.00
147_G	199_F	3.266	1.00
283_S	348_D	3.259	1.00
402_G	425_G	3.247	1.00
403_F	422_M	3.159	1.00
396_V	399_A	2.990	1.00
14_G	274_F	2.931	1.00
486_A	517_A	2.903	1.00
399_A	403_F	2.901	1.00
223_D	226_Q	2.870	1.00
120_I	215_V	2.859	1.00
389_I	597_K	2.854	1.00
113_L	226_Q	2.772	1.00
10_V	278_G	2.701	1.00
392_L	438_V	2.672	1.00
386_G	431_F	2.650	1.00
562_V	566_L	2.613	1.00
284_E	287_A	2.580	1.00
120_I	219_R	2.536	1.00
390_G	597_K	2.529	1.00
402_G	422_M	2.506	1.00
399_A	422_M	2.494	1.00
554_L	557_A	2.492	1.00
514_L	547_P	2.490	1.00
384_F	590_I	2.444	1.00
6_Q	369_T	2.412	1.00
382_P	427_F	2.319	1.00
116_V	222_R	2.292	1.00
506_A	510_G	2.284	1.00
84_T	87_A	2.264	1.00
224_T	228_E	2.255	1.00
120_I	218_L	2.239	1.00
433_V	438_V	2.121	0.99
376_V	491_F	2.097	0.99
493_F	505_A	2.089	0.99
286_D	289_T	2.085	0.99
399_A	429_A	2.082	0.99
547_P	550_G	2.081	0.99
350_P	353_V	2.073	0.99
493_F	497_S	2.070	0.99
278_G	439_F	2.059	0.99
394_Y	597_K	2.039	0.99
591_A	597_K	2.033	0.99
400_L	404_W	2.027	0.99
220_E	224_T	2.004	0.99
221_R	224_T	1.994	0.99
553_G	556_A	1.989	0.99
399_A	426_G	1.956	0.99
32_V	278_G	1.944	0.99
459_P	463_G	1.940	0.99
223_D	227_A	1.938	0.99
474_L	588_T	1.936	0.99
104_D	108_E	1.917	0.99
290_D	294_S	1.893	0.99
425_G	429_A	1.892	0.99
6_Q	282_T	1.880	0.99
550_G	554_L	1.860	0.99
396_V	438_V	1.859	0.99
14_G	22_V	1.852	0.99
124_E	219_R	1.852	0.99
382_P	437_E	1.836	0.98
234_D	238_A	1.833	0.98
355_S	358_S	1.823	0.98
194_L	199_F	1.820	0.98
349_N	357_E	1.817	0.98
524_F	528_M	1.806	0.98
561_L	564_V	1.802	0.98
390_G	435_Y	1.800	0.98
489_Y	576_S	1.797	0.98
511_G	514_L	1.776	0.98
8_S	285_Y	1.775	0.98
492_G	509_S	1.771	0.98
514_L	518_G	1.771	0.98
227_A	230_E	1.768	0.98
540_Y	543_V	1.752	0.98
402_G	418_G	1.742	0.98
216_S	220_E	1.734	0.98
106_R	233_D	1.733	0.98
261_S	264_P	1.725	0.98
284_E	346_I	1.713	0.98
553_G	557_A	1.690	0.97
584_T	597_K	1.685	0.97
551_K	555_A	1.671	0.97
479_V	523_L	1.654	0.97
281_P	284_E	1.646	0.97
414_I	417_L	1.629	0.97
504_D	508_E	1.619	0.97
353_V	374_T	1.617	0.97
551_K	557_A	1.601	0.96
470_A	591_A	1.595	0.96
507_L	554_L	1.585	0.96
426_G	430_L	1.575	0.96
213_Q	217_E	1.572	0.96
384_F	480_F	1.568	0.96
113_L	225_I	1.560	0.96
212_E	216_S	1.551	0.96
415_S	418_G	1.551	0.96
490_V	494_V	1.549	0.96
403_F	407_R	1.547	0.96
535_R	539_L	1.527	0.95
395_G	429_A	1.525	0.95
11_S	277_E	1.517	0.95
230_E	234_D	1.516	0.95
461_K	464_L	1.510	0.95
394_Y	601_A	1.492	0.95
575_E	583_N	1.491	0.95
413_M	417_L	1.488	0.94
102_L	232_V	1.477	0.94
470_A	585_V	1.456	0.94
588_T	594_L	1.454	0.94
117_I	226_Q	1.451	0.94
599_G	603_V	1.447	0.94
226_Q	230_E	1.446	0.94
216_S	219_R	1.446	0.94
231_D	234_D	1.437	0.93
495_N	499_S	1.419	0.93
463_G	466_V	1.410	0.93
411_S	418_G	1.410	0.93
492_G	496_E	1.402	0.92
422_M	426_G	1.388	0.92
585_V	603_V	1.386	0.92
583_N	597_K	1.382	0.92
582_V	599_G	1.377	0.92
110_T	233_D	1.376	0.92
465_H	468_A	1.375	0.92
289_T	293_E	1.375	0.92
578_T	583_N	1.372	0.92
232_V	235_E	1.365	0.91
394_Y	605_N	1.343	0.91
235_E	238_A	1.343	0.91
29_A	288_F	1.341	0.91
575_E	578_T	1.320	0.90
99_A	360_T	1.319	0.90
111_D	115_A	1.311	0.90
547_P	555_A	1.308	0.90
5_E	348_D	1.304	0.89
122_A	288_F	1.301	0.89
389_I	394_Y	1.283	0.89
116_V	221_R	1.283	0.89
388_M	435_Y	1.281	0.89
79_P	84_T	1.279	0.88
23_I	267_F	1.279	0.88
349_N	372_D	1.273	0.88
547_P	556_A	1.272	0.88
270_T	273_A	1.270	0.88
406_S	422_M	1.269	0.88
596_A	600_M	1.268	0.88
381_F	437_E	1.262	0.88
222_R	226_Q	1.261	0.88
376_V	484_H	1.258	0.88
389_I	584_T	1.253	0.87
539_L	543_V	1.252	0.87
484_H	488_G	1.251	0.87
547_P	557_A	1.248	0.87
495_N	575_E	1.248	0.87
547_P	554_L	1.242	0.87
488_G	587_Y	1.242	0.87
382_P	575_E	1.240	0.87
110_T	229_I	1.236	0.87
290_D	293_E	1.234	0.87
109_L	229_I	1.232	0.87
347_Q	366_P	1.229	0.86
547_P	551_K	1.227	0.86
588_T	591_A	1.227	0.86
562_V	565_T	1.224	0.86
551_K	554_L	1.220	0.86
66_L	69_L	1.219	0.86
547_P	611_A	1.215	0.86
390_G	473_W	1.215	0.86
218_L	222_R	1.211	0.86
550_G	555_A	1.211	0.86
530_S	533_G	1.204	0.85
502_L	506_A	1.198	0.85
370_E	495_N	1.197	0.85
62_T	69_L	1.197	0.85
107_S	111_D	1.189	0.84
508_E	512_Q	1.189	0.84
402_G	406_S	1.184	0.84
587_Y	590_I	1.183	0.84
466_V	470_A	1.182	0.84
343_P	364_N	1.181	0.84
389_I	588_T	1.180	0.84
124_E	215_V	1.176	0.84
280_L	288_F	1.173	0.84
281_P	346_I	1.173	0.84
459_P	462_K	1.169	0.83
394_Y	590_I	1.167	0.83
30_E	288_F	1.167	0.83
538_L	542_V	1.154	0.83
575_E	597_K	1.150	0.82
94_S	98_E	1.143	0.82
95_I	598_A	1.142	0.82
434_L	494_V	1.140	0.82
412_E	416_K	1.138	0.82
415_S	483_A	1.136	0.82
353_V	357_E	1.132	0.81
63_V	215_V	1.129	0.81
228_E	232_V	1.123	0.81
372_D	394_Y	1.116	0.80
98_E	235_E	1.116	0.80
261_S	265_L	1.113	0.80
394_Y	512_Q	1.111	0.80
132_D	135_L	1.108	0.80
251_E	255_A	1.105	0.80
394_Y	583_N	1.102	0.80
543_V	548_I	1.098	0.79
468_A	471_E	1.097	0.79
15_S	18_V	1.092	0.79
217_E	221_R	1.092	0.79
493_F	510_G	1.090	0.79
389_I	428_T	1.081	0.78
597_K	600_M	1.081	0.78
363_I	593_V	1.079	0.78
297_G	403_F	1.078	0.78
60_L	118_E	1.071	0.78
86_D	290_D	1.068	0.77
225_I	228_E	1.068	0.77
387_F	435_Y	1.067	0.77
110_T	113_L	1.060	0.77
63_V	146_V	1.047	0.76
279_W	592_A	1.045	0.76
490_V	513_L	1.044	0.76
571_A	575_E	1.044	0.76
496_E	509_S	1.044	0.76
104_D	134_D	1.041	0.76
121_D	124_E	1.036	0.75
470_A	474_L	1.036	0.75
448_L	452_A	1.035	0.75
117_I	222_R	1.029	0.75
288_F	292_I	1.029	0.75
460_L	463_G	1.028	0.75
549_V	553_G	1.026	0.75
52_G	55_E	1.024	0.74
574_L	583_N	1.023	0.74
64_R	70_L	1.023	0.74
394_Y	584_T	1.020	0.74
71_D	500_H	1.018	0.74
124_E	216_S	1.017	0.74
110_T	225_I	1.014	0.74
564_V	568_E	1.013	0.74
161_S	164_I	1.012	0.74
569_G	573_F	1.011	0.73
5_E	283_S	1.009	0.73
351_G	419_G	1.009	0.73
300_V	303_E	1.008	0.73
285_Y	304_E	1.007	0.73
393_G	397_L	1.005	0.73
147_G	150_D	1.004	0.73
64_R	251_E	1.003	0.73
99_A	236_L	1.002	0.73
446_E	450_H	1.001	0.73
413_M	416_K	0.997	0.72
31_L	288_F	0.995	0.72
213_Q	216_S	0.991	0.72
10_V	288_F	0.983	0.71
543_V	553_G	0.982	0.71
106_R	232_V	0.981	0.71
27_H	394_Y	0.981	0.71
514_L	554_L	0.979	0.71
389_I	601_A	0.979	0.71
381_F	471_E	0.979	0.71
544_A	548_I	0.976	0.71
548_I	554_L	0.975	0.71
102_L	106_R	0.972	0.70
387_F	480_F	0.970	0.70
513_L	587_Y	0.967	0.70
522_W	539_L	0.966	0.70
161_S	190_L	0.964	0.70
186_D	189_A	0.964	0.70
347_Q	365_R	0.961	0.70
484_H	593_V	0.959	0.69
384_F	387_F	0.959	0.69
392_L	443_L	0.957	0.69
116_V	120_I	0.957	0.69
343_P	368_Y	0.954	0.69
350_P	375_V	0.951	0.69
107_S	110_T	0.950	0.69
437_E	575_E	0.949	0.69
348_D	500_H	0.946	0.68
581_L	588_T	0.944	0.68
25_A	291_A	0.942	0.68
503_K	507_L	0.941	0.68
493_F	509_S	0.938	0.68
32_V	87_A	0.937	0.68
106_R	229_I	0.936	0.68
586_S	589_R	0.934	0.67
49_P	56_A	0.928	0.67
552_A	555_A	0.927	0.67
64_R	68_S	0.926	0.67
70_L	73_S	0.925	0.67
584_T	588_T	0.922	0.66
515_L	519_V	0.921	0.66
565_T	568_E	0.921	0.66
260_K	394_Y	0.921	0.66
238_A	242_E	0.920	0.66
18_V	21_P	0.920	0.66
384_F	582_V	0.913	0.66
25_A	296_V	0.912	0.66
424_A	585_V	0.909	0.65
535_R	538_L	0.903	0.65
435_Y	592_A	0.902	0.65
90_T	93_E	0.902	0.65
470_A	473_W	0.899	0.64
12_V	32_V	0.896	0.64
361_E	365_R	0.895	0.64
202_L	603_V	0.892	0.64
467_S	470_A	0.890	0.64
574_L	578_T	0.890	0.64
592_A	601_A	0.888	0.63
10_V	32_V	0.888	0.63
387_F	431_F	0.885	0.63
389_I	591_A	0.884	0.63
222_R	237_A	0.882	0.63
435_Y	473_W	0.881	0.63
88_L	250_A	0.881	0.63
370_E	388_M	0.876	0.62
469_F	473_W	0.872	0.62
53_A	57_A	0.870	0.62
180_A	250_A	0.868	0.62
388_M	594_L	0.867	0.62
399_A	410_D	0.865	0.61
565_T	574_L	0.862	0.61
442_H	478_L	0.862	0.61
253_R	590_I	0.861	0.61
120_I	222_R	0.860	0.61
115_A	254_L	0.859	0.61
353_V	378_F	0.859	0.61
417_L	420_V	0.857	0.61
60_L	64_R	0.857	0.61
27_H	588_T	0.855	0.60
26_V	30_E	0.854	0.60
431_F	480_F	0.853	0.60
405_L	414_I	0.852	0.60
142_L	401_L	0.851	0.60
364_N	389_I	0.850	0.60
27_H	260_K	0.849	0.60
144_V	184_A	0.849	0.60
406_S	419_G	0.848	0.60
565_T	572_G	0.848	0.60
90_T	94_S	0.848	0.60
509_S	575_E	0.845	0.60
148_T	345_V	0.845	0.60
13_A	275_V	0.844	0.59
493_F	512_Q	0.844	0.59
62_T	66_L	0.844	0.59
147_G	194_L	0.842	0.59
98_E	239_F	0.838	0.59
26_V	288_F	0.838	0.59
431_F	594_L	0.836	0.59
109_L	221_R	0.836	0.59
336_S	339_E	0.836	0.59
15_S	435_Y	0.835	0.59
231_D	302_V	0.835	0.59
25_A	295_A	0.834	0.59
453_L	458_A	0.834	0.59
173_Q	371_I	0.832	0.58
581_L	591_A	0.829	0.58
478_L	588_T	0.827	0.58
512_Q	587_Y	0.826	0.58
103_D	106_R	0.825	0.58
352_P	484_H	0.823	0.58
583_N	605_N	0.823	0.58
52_G	89_D	0.821	0.57
357_E	361_E	0.821	0.57
112_D	115_A	0.820	0.57
594_L	597_K	0.818	0.57
388_M	593_V	0.817	0.57
505_A	510_G	0.815	0.57
485_L	580_A	0.814	0.57
58_E	61_V	0.814	0.57
108_E	112_D	0.814	0.57
387_F	594_L	0.810	0.56
286_D	290_D	0.807	0.56
396_V	443_L	0.807	0.56
214_Y	218_L	0.805	0.56
213_Q	223_D	0.805	0.56
489_Y	580_A	0.805	0.56
587_Y	593_V	0.804	0.56
488_G	512_Q	0.804	0.56
27_H	582_V	0.801	0.55
563_L	566_L	0.800	0.55
156_A	160_A	0.800	0.55
179_F	221_R	0.800	0.55
209_G	213_Q	0.799	0.55
396_V	550_G	0.798	0.55
355_S	420_V	0.798	0.55
56_A	60_L	0.797	0.55
168_E	171_T	0.797	0.55
390_G	598_A	0.797	0.55
415_S	419_G	0.795	0.55
267_F	276_A	0.794	0.55
578_T	585_V	0.794	0.55
522_W	526_T	0.794	0.55
485_L	596_A	0.793	0.55
105_R	235_E	0.791	0.55
62_T	100_T	0.790	0.54
544_A	547_P	0.789	0.54
511_G	593_V	0.788	0.54
467_S	582_V	0.786	0.54
9_K	35_S	0.785	0.54
561_L	565_T	0.783	0.54
197_V	205_P	0.780	0.53
395_G	425_G	0.780	0.53
49_P	57_A	0.779	0.53
76_D	399_A	0.779	0.53
227_A	231_D	0.779	0.53
591_A	594_L	0.779	0.53
475_A	522_W	0.778	0.53
60_L	74_E	0.776	0.53
466_V	473_W	0.776	0.53
443_L	590_I	0.776	0.53
548_I	553_G	0.775	0.53
488_G	592_A	0.774	0.53
56_A	254_L	0.772	0.53
390_G	591_A	0.772	0.53
394_Y	591_A	0.772	0.53
76_D	290_D	0.769	0.52
390_G	431_F	0.766	0.52
548_I	556_A	0.765	0.52
67_K	72_V	0.765	0.52
92_L	286_D	0.764	0.52
9_K	394_Y	0.763	0.52
230_E	483_A	0.763	0.52
57_A	61_V	0.762	0.52
270_T	277_E	0.759	0.51
99_A	566_L	0.757	0.51
510_G	514_L	0.756	0.51
582_V	606_L	0.756	0.51
71_D	94_S	0.755	0.51
403_F	406_S	0.754	0.51
66_L	70_L	0.753	0.51
378_F	382_P	0.752	0.51
171_T	223_D	0.752	0.51
55_E	146_V	0.749	0.51
497_S	502_L	0.748	0.50
537_E	540_Y	0.748	0.50
597_K	605_N	0.747	0.50
119_R	218_L	0.747	0.50
421_A	434_L	0.747	0.50
220_E	223_D	0.744	0.50
419_G	423_W	0.744	0.50
66_L	73_S	0.743	0.50
338_D	429_A	0.742	0.50
521_V	526_T	0.742	0.50
489_Y	583_N	0.741	0.50
429_A	438_V	0.737	0.49
140_D	143_Q	0.735	0.49
394_Y	587_Y	0.733	0.49
84_T	88_L	0.732	0.49
52_G	491_F	0.731	0.49
6_Q	365_R	0.731	0.49
569_G	576_S	0.731	0.49
87_A	483_A	0.730	0.49
108_E	115_A	0.730	0.49
601_A	605_N	0.730	0.49
465_H	470_A	0.729	0.49
568_E	572_G	0.729	0.49
355_S	362_V	0.729	0.49
394_Y	428_T	0.728	0.49
470_A	594_L	0.728	0.49
413_M	549_V	0.727	0.48
512_Q	518_G	0.727	0.48
399_A	438_V	0.726	0.48
59_K	93_E	0.726	0.48
470_A	588_T	0.726	0.48
219_R	223_D	0.725	0.48
572_G	576_S	0.724	0.48
78_G	229_I	0.724	0.48
585_V	599_G	0.724	0.48
159_A	596_A	0.723	0.48
588_T	605_N	0.722	0.48
540_Y	544_A	0.720	0.48
518_G	593_V	0.719	0.48
382_P	565_T	0.717	0.47
515_L	572_G	0.717	0.47
154_I	476_A	0.717	0.47
358_S	516_M	0.717	0.47
389_I	594_L	0.714	0.47
578_T	582_V	0.713	0.47
566_L	570_A	0.711	0.47
27_H	594_L	0.710	0.47
175_T	181_Y	0.710	0.47
80_T	84_T	0.709	0.47
604_V	610_G	0.709	0.47
117_I	247_L	0.706	0.46
578_T	591_A	0.706	0.46
57_A	73_S	0.704	0.46
260_K	512_Q	0.704	0.46
390_G	511_G	0.702	0.46
447_Y	582_V	0.701	0.46
515_L	522_W	0.701	0.46
494_V	498_R	0.701	0.46
572_G	583_N	0.698	0.46
292_I	300_V	0.697	0.46
397_L	466_V	0.697	0.46
394_Y	593_V	0.696	0.46
229_I	403_F	0.696	0.46
113_L	259_Q	0.695	0.45
9_K	341_D	0.695	0.45
357_E	569_G	0.691	0.45
524_F	550_G	0.689	0.45
219_R	226_Q	0.687	0.45
61_V	64_R	0.686	0.45
225_I	545_L	0.686	0.45
193_A	383_A	0.686	0.45
435_Y	603_V	0.685	0.44
491_F	539_L	0.685	0.44
424_A	591_A	0.685	0.44
523_L	527_H	0.684	0.44
63_V	298_D	0.684	0.44
364_N	588_T	0.683	0.44
354_S	416_K	0.683	0.44
423_W	496_E	0.683	0.44
528_M	577_P	0.682	0.44
133_L	175_T	0.682	0.44
538_L	541_S	0.682	0.44
394_Y	594_L	0.681	0.44
132_D	516_M	0.681	0.44
376_V	487_I	0.680	0.44
543_V	551_K	0.678	0.44
63_V	541_S	0.678	0.44
55_E	58_E	0.678	0.44
93_E	238_A	0.676	0.44
105_R	232_V	0.674	0.43
503_K	506_A	0.674	0.43
536_P	539_L	0.672	0.43
112_D	224_T	0.671	0.43
496_E	504_D	0.670	0.43
66_L	76_D	0.669	0.43
7_M	274_F	0.666	0.43
582_V	591_A	0.665	0.43
495_N	509_S	0.663	0.42
427_F	436_G	0.662	0.42
27_H	597_K	0.661	0.42
459_P	464_L	0.660	0.42
83_V	87_A	0.660	0.42
550_G	553_G	0.659	0.42
113_L	117_I	0.658	0.42
428_T	511_G	0.658	0.42
104_D	174_D	0.657	0.42
585_V	591_A	0.657	0.42
511_G	516_M	0.653	0.41
387_F	476_A	0.653	0.41
443_L	587_Y	0.652	0.41
27_H	389_I	0.651	0.41
479_V	483_A	0.651	0.41
389_I	512_Q	0.651	0.41
129_L	211_P	0.651	0.41
248_L	506_A	0.651	0.41
412_E	418_G	0.650	0.41
368_Y	435_Y	0.649	0.41
380_T	583_N	0.649	0.41
273_A	296_V	0.649	0.41
278_G	459_P	0.649	0.41
368_Y	590_I	0.649	0.41
126_F	431_F	0.647	0.41
530_S	534_P	0.646	0.41
363_I	388_M	0.646	0.41
547_P	553_G	0.645	0.41
64_R	71_D	0.644	0.41
551_K	556_A	0.643	0.41
384_F	588_T	0.642	0.40
94_S	248_L	0.641	0.40
443_L	593_V	0.640	0.40
134_D	160_A	0.640	0.40
443_L	446_E	0.640	0.40
536_P	549_V	0.639	0.40
399_A	407_R	0.639	0.40
394_Y	518_G	0.638	0.40
477_S	509_S	0.637	0.40
532_G	535_R	0.637	0.40
27_H	571_A	0.636	0.40
428_T	597_K	0.636	0.40
48_D	87_A	0.635	0.40
279_W	511_G	0.634	0.40
394_Y	575_E	0.634	0.40
351_G	523_L	0.633	0.40
397_L	421_A	0.633	0.40
388_M	582_V	0.633	0.40
386_G	428_T	0.633	0.40
224_T	227_A	0.632	0.40
291_A	354_S	0.631	0.39
99_A	222_R	0.629	0.39
181_Y	187_D	0.629	0.39
564_V	567_G	0.629	0.39
133_L	159_A	0.628	0.39
252_E	560_G	0.628	0.39
284_E	519_V	0.625	0.39
380_T	578_T	0.624	0.39
435_Y	479_V	0.624	0.39
571_A	599_G	0.622	0.39
489_Y	593_V	0.621	0.39
513_L	517_A	0.620	0.38
124_E	233_D	0.620	0.38
85_D	246_F	0.620	0.38
279_W	417_L	0.620	0.38
599_G	602_Y	0.620	0.38
444_V	593_V	0.619	0.38
573_F	584_T	0.618	0.38
511_G	518_G	0.617	0.38
366_P	386_G	0.617	0.38
62_T	303_E	0.617	0.38
231_D	235_E	0.617	0.38
467_S	599_G	0.616	0.38
139_Y	398_Y	0.616	0.38
595_L	603_V	0.615	0.38
29_A	291_A	0.615	0.38
140_D	180_A	0.612	0.38
590_I	593_V	0.611	0.38
535_R	540_Y	0.611	0.38
287_A	290_D	0.611	0.38
417_L	421_A	0.610	0.38
366_P	586_S	0.608	0.37
446_E	452_A	0.608	0.37
520_G	607_L	0.608	0.37
101_D	134_D	0.608	0.37
364_N	584_T	0.608	0.37
437_E	583_N	0.607	0.37
525_S	542_V	0.607	0.37
512_Q	605_N	0.607	0.37
436_G	591_A	0.607	0.37
406_S	420_V	0.606	0.37
15_S	19_L	0.606	0.37
45_D	190_L	0.605	0.37
281_P	403_F	0.605	0.37
394_Y	600_M	0.603	0.37
569_G	574_L	0.602	0.37
345_V	387_F	0.601	0.37
294_S	483_A	0.601	0.37
371_I	376_V	0.601	0.37
357_E	527_H	0.601	0.37
420_V	467_S	0.601	0.37
565_T	580_A	0.600	0.37
213_Q	425_G	0.599	0.37
600_M	604_V	0.598	0.37
348_D	519_V	0.598	0.37
65_S	92_L	0.598	0.37
260_K	605_N	0.597	0.36
88_L	91_E	0.596	0.36
128_D	223_D	0.595	0.36
47_G	51_T	0.594	0.36
27_H	578_T	0.594	0.36
345_V	370_E	0.593	0.36
105_R	108_E	0.593	0.36
543_V	546_P	0.593	0.36
540_Y	555_A	0.592	0.36
410_D	487_I	0.592	0.36
284_E	500_H	0.592	0.36
63_V	254_L	0.591	0.36
217_E	286_D	0.590	0.36
389_I	511_G	0.590	0.36
546_P	553_G	0.588	0.36
59_K	89_D	0.588	0.36
391_D	589_R	0.588	0.36
68_S	247_L	0.588	0.36
465_H	473_W	0.587	0.36
363_I	385_Y	0.587	0.36
173_Q	549_V	0.586	0.35
58_E	66_L	0.585	0.35
144_V	189_A	0.584	0.35
229_I	233_D	0.584	0.35
571_A	591_A	0.584	0.35
372_D	576_S	0.582	0.35
470_A	597_K	0.582	0.35
435_Y	441_L	0.582	0.35
366_P	589_R	0.582	0.35
274_F	582_V	0.581	0.35
394_Y	484_H	0.581	0.35
289_T	477_S	0.581	0.35
186_D	193_A	0.581	0.35
288_F	406_S	0.581	0.35
33_H	288_F	0.581	0.35
89_D	269_S	0.580	0.35
576_S	588_T	0.579	0.35
536_P	541_S	0.578	0.35
573_F	576_S	0.577	0.35
63_V	219_R	0.576	0.35
512_Q	593_V	0.576	0.35
578_T	597_K	0.576	0.35
121_D	164_I	0.573	0.34
383_A	482_I	0.573	0.34
398_Y	402_G	0.572	0.34
389_I	582_V	0.572	0.34
512_Q	600_M	0.572	0.34
536_P	542_V	0.572	0.34
433_V	467_S	0.570	0.34
172_G	175_T	0.570	0.34
545_L	555_A	0.569	0.34
382_P	424_A	0.568	0.34
475_A	479_V	0.568	0.34
288_F	386_G	0.568	0.34
65_S	69_L	0.567	0.34
488_G	593_V	0.567	0.34
390_G	594_L	0.566	0.34
68_S	215_V	0.566	0.34
70_L	75_G	0.566	0.34
243_H	506_A	0.566	0.34
115_A	123_A	0.566	0.34
50_M	218_L	0.566	0.34
239_F	254_L	0.565	0.34
11_S	268_A	0.564	0.34
599_G	604_V	0.564	0.34
132_D	380_T	0.563	0.33
358_S	413_M	0.563	0.33
389_I	571_A	0.562	0.33
97_V	101_D	0.562	0.33
242_E	245_G	0.562	0.33
10_V	300_V	0.561	0.33
155_D	158_L	0.561	0.33
132_D	204_V	0.561	0.33
186_D	270_T	0.560	0.33
15_S	304_E	0.559	0.33
357_E	594_L	0.559	0.33
234_D	237_A	0.559	0.33
54_D	66_L	0.559	0.33
512_Q	583_N	0.557	0.33
409_F	415_S	0.557	0.33
87_A	286_D	0.557	0.33
68_S	290_D	0.557	0.33
431_F	593_V	0.557	0.33
437_E	441_L	0.556	0.33
572_G	588_T	0.555	0.33
257_D	576_S	0.554	0.33
344_P	589_R	0.554	0.33
290_D	403_F	0.553	0.33
593_V	597_K	0.553	0.33
568_E	575_E	0.553	0.33
435_Y	594_L	0.553	0.33
486_A	516_M	0.552	0.33
496_E	506_A	0.552	0.33
221_R	225_I	0.552	0.33
55_E	59_K	0.551	0.32
71_D	286_D	0.550	0.32
367_Q	370_E	0.550	0.32
518_G	583_N	0.549	0.32
595_L	598_A	0.549	0.32
575_E	579_Y	0.549	0.32
91_E	124_E	0.547	0.32
487_I	496_E	0.547	0.32
126_F	439_F	0.547	0.32
252_E	360_T	0.547	0.32
167_F	249_A	0.547	0.32
284_E	348_D	0.547	0.32
384_F	406_S	0.546	0.32
356_F	423_W	0.545	0.32
222_R	478_L	0.544	0.32
574_L	593_V	0.544	0.32
471_E	595_L	0.543	0.32
391_D	586_S	0.543	0.32
119_R	581_L	0.542	0.32
12_V	113_L	0.542	0.32
260_K	597_K	0.542	0.32
445_T	588_T	0.541	0.32
24_E	260_K	0.541	0.32
561_L	602_Y	0.541	0.32
214_Y	225_I	0.540	0.32
593_V	604_V	0.540	0.32
274_F	435_Y	0.540	0.32
571_A	588_T	0.540	0.32
216_S	234_D	0.539	0.31
574_L	580_A	0.539	0.31
160_A	166_A	0.539	0.31
229_I	473_W	0.539	0.31
453_L	531_G	0.539	0.31
222_R	229_I	0.538	0.31
437_E	580_A	0.538	0.31
63_V	248_L	0.537	0.31
95_I	241_D	0.536	0.31
335_A	477_S	0.535	0.31
60_L	70_L	0.535	0.31
38_D	131_I	0.534	0.31
510_G	518_G	0.533	0.31
596_A	604_V	0.532	0.31
552_A	556_A	0.531	0.31
267_F	375_V	0.531	0.31
425_G	597_K	0.530	0.31
389_I	411_S	0.529	0.31
382_P	390_G	0.529	0.31
288_F	402_G	0.529	0.31
357_E	372_D	0.528	0.31
416_K	590_I	0.527	0.31
36_D	592_A	0.526	0.30
511_G	591_A	0.526	0.30
356_F	600_M	0.526	0.30
13_A	472_L	0.525	0.30
428_T	587_Y	0.524	0.30
345_V	365_R	0.524	0.30
216_S	227_A	0.524	0.30
480_F	510_G	0.523	0.30
64_R	223_D	0.522	0.30
596_A	607_L	0.522	0.30
435_Y	578_T	0.522	0.30
458_A	461_K	0.521	0.30
193_A	493_F	0.520	0.30
27_H	492_G	0.519	0.30
225_I	429_A	0.519	0.30
50_M	53_A	0.519	0.30
452_A	460_L	0.519	0.30
540_Y	570_A	0.518	0.30
360_T	379_L	0.518	0.30
518_G	605_N	0.518	0.30
512_Q	576_S	0.517	0.30
59_K	254_L	0.517	0.30
405_L	565_T	0.517	0.30
479_V	513_L	0.516	0.30
536_P	540_Y	0.516	0.30
575_E	600_M	0.516	0.30
424_A	603_V	0.515	0.30
134_D	193_A	0.514	0.29
388_M	603_V	0.513	0.29
205_P	359_L	0.512	0.29
380_T	597_K	0.512	0.29
234_D	506_A	0.511	0.29
374_T	377_L	0.511	0.29
595_L	599_G	0.511	0.29
34_L	263_A	0.510	0.29
344_P	586_S	0.510	0.29
26_V	191_D	0.509	0.29
368_Y	478_L	0.508	0.29
363_I	590_I	0.508	0.29
356_F	388_M	0.508	0.29
71_D	74_E	0.508	0.29
427_F	473_W	0.508	0.29
544_A	555_A	0.508	0.29
447_Y	451_G	0.507	0.29
71_D	98_E	0.507	0.29
51_T	54_D	0.507	0.29
185_D	283_S	0.506	0.29
382_P	603_V	0.506	0.29
190_L	212_E	0.506	0.29
117_I	246_F	0.506	0.29
496_E	505_A	0.506	0.29
359_L	566_L	0.506	0.29
473_W	591_A	0.506	0.29
121_D	223_D	0.506	0.29
545_L	557_A	0.505	0.29
437_E	597_K	0.505	0.29
394_Y	588_T	0.504	0.29
572_G	582_V	0.504	0.29
427_F	431_F	0.503	0.29
39_G	429_A	0.503	0.29
109_L	417_L	0.502	0.29
389_I	575_E	0.502	0.29
213_Q	528_M	0.501	0.28
101_D	287_A	0.501	0.28
267_F	278_G	0.501	0.28
397_L	486_A	0.500	0.28

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3j9tb	1	0.3809	100	0.404	Contact Map
3rrkA	1	0.3989	100	0.729	Contact Map
2jtwA	1	0.0346	95.8	0.968	Contact Map
1i84S	2	0.0817	92.2	0.973	Contact Map
3ojaB	1	0.2271	91.6	0.973	Contact Map
2dfsA	2	0.1967	91.6	0.973	Contact Map
1u7lA	1	0.4058	91.3	0.973	Contact Map
1fxkC	2	0.1842	86	0.976	Contact Map
4cgkA	3	0.4238	84.9	0.976	Contact Map
1fxkA	2	0.1482	82.3	0.977	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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