GREMLIN Database
Q9HND3 - Electron transfer flavoprotein subunit beta
UniProt: Q9HND3 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 266 (244)
Sequences: 3515 (2037)
Seq/√Len: 130.4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
159_V175_D4.1891.00
55_E80_R3.7481.00
131_G183_T3.3091.00
106_A109_E3.2411.00
48_A79_D3.2101.00
70_I81_A3.1661.00
148_D163_R3.0071.00
211_S214_D2.9581.00
110_D210_K2.9571.00
58_A73_A2.8001.00
43_E46_Q2.6381.00
80_R208_A2.6101.00
143_A176_V2.4091.00
2_K55_E2.4051.00
256_D260_D2.3731.00
118_S134_L2.3271.00
74_L81_A2.3001.00
43_E189_N2.2341.00
146_V162_V2.1101.00
49_E192_R2.0981.00
4_L108_V2.0971.00
42_E192_R2.0911.00
33_L69_T2.0811.00
146_V182_L2.0121.00
160_A176_V1.9781.00
176_V180_A1.9721.00
161_S175_D1.9631.00
105_A109_E1.9631.00
41_V78_A1.9631.00
6_T118_S1.9191.00
57_V82_V1.8991.00
116_V140_V1.8291.00
84_V103_L1.7841.00
150_D161_S1.7621.00
245_G253_G1.7581.00
67_E71_R1.7261.00
164_R171_E1.7251.00
115_L180_A1.7241.00
241_E257_V1.7101.00
34_N37_D1.7041.00
57_V80_R1.6961.00
101_A137_T1.6891.00
64_E85_W1.6871.00
121_Q126_S1.6731.00
110_D208_A1.6591.00
60_T66_A1.6391.00
253_G256_D1.6391.00
4_L113_P1.6311.00
160_A178_L1.6291.00
108_V116_V1.5851.00
184_I188_I1.5731.00
58_A78_A1.5691.00
56_V78_A1.5431.00
163_R172_E1.5091.00
195_S198_G1.4941.00
84_V107_V1.4931.00
59_V107_V1.4931.00
151_T160_A1.4801.00
85_W209_P1.4561.00
135_A142_W1.4411.00
63_P66_A1.4141.00
47_L51_G1.3991.00
88_A213_D1.3771.00
82_V107_V1.3661.00
57_V113_P1.3561.00
92_T103_L1.3531.00
244_E253_G1.3451.00
241_E253_G1.3401.00
158_G177_E1.3391.00
2_K57_V1.3131.00
44_A56_V1.2991.00
150_D156_D1.2931.00
159_V177_E1.2881.00
83_R209_P1.2731.00
67_E209_P1.2721.00
110_D215_L1.2541.00
50_A150_D1.2371.00
58_A70_I1.2311.00
140_V181_V1.2201.00
74_L205_K1.2010.99
41_V76_K1.1930.99
147_N163_R1.1890.99
25_E28_Y1.1880.99
43_E188_I1.1760.99
104_L134_L1.1690.99
210_K215_L1.1680.99
156_D161_S1.1650.99
252_S255_A1.1600.99
39_Y189_N1.1570.99
99_T224_S1.1370.99
60_T83_R1.1360.99
197_R201_Q1.1350.99
122_A125_D1.1340.99
33_L73_A1.1310.99
45_V198_G1.1260.99
43_E149_L1.1190.99
105_A138_L1.1010.99
85_W211_S1.1000.99
82_V210_K1.0940.99
150_D163_R1.0930.99
102_R106_A1.0900.99
260_D263_V1.0800.99
2_K112_D1.0770.99
102_R137_T1.0720.99
117_F182_L1.0650.99
143_A162_V1.0620.99
4_L59_V1.0610.99
48_A54_V1.0530.99
114_E158_G1.0530.99
45_V76_K1.0530.99
151_T156_D1.0460.99
212_L219_A1.0360.98
161_S172_E1.0350.98
199_I205_K1.0350.98
108_V134_L1.0340.98
257_V260_D1.0310.98
7_V73_A1.0190.98
36_W120_V1.0120.98
156_D159_V1.0020.98
132_I142_W1.0020.98
212_L217_L0.9970.98
251_A255_A0.9960.98
42_E46_Q0.9950.98
42_E191_P0.9920.98
51_G54_V0.9910.98
7_V41_V0.9770.98
141_Q180_A0.9690.98
9_E69_T0.9660.97
88_A212_L0.9650.97
218_D223_A0.9600.97
7_V69_T0.9590.97
149_L162_V0.9540.97
38_D76_K0.9480.97
45_V49_E0.9420.97
39_Y187_G0.9360.97
43_E148_D0.9320.97
64_E67_E0.9290.97
197_R200_R0.9280.97
116_V134_L0.9270.97
257_V261_A0.9260.97
109_E112_D0.9240.97
66_A83_R0.9210.97
6_T134_L0.9150.97
233_E236_T0.9070.96
133_A137_T0.9050.96
67_E83_R0.8990.96
151_T178_L0.8970.96
200_R203_Q0.8940.96
117_F184_I0.8930.96
103_L215_L0.8920.96
166_L169_G0.8920.96
61_I100_K0.8920.96
163_R170_V0.8880.96
128_G132_I0.8870.96
101_A133_A0.8780.96
7_V58_A0.8680.95
106_A110_D0.8660.95
218_D224_S0.8650.95
113_P140_V0.8610.95
103_L212_L0.8580.95
106_A215_L0.8580.95
76_K191_P0.8560.95
118_S181_V0.8530.95
38_D72_M0.8500.95
40_A184_I0.8490.95
132_I144_A0.8480.95
13_V32_D0.8450.95
193_Y199_I0.8420.94
67_E207_I0.8410.94
237_E240_A0.8380.94
108_V113_P0.8360.94
151_T157_E0.8360.94
88_A219_A0.8350.94
63_P83_R0.8350.94
6_T104_L0.8340.94
122_A126_S0.8300.94
149_L160_A0.8290.94
105_A134_L0.8240.94
160_A182_L0.8230.94
86_D212_L0.8220.94
80_R111_E0.8200.94
108_V138_L0.8170.94
5_V56_V0.8160.94
11_A26_S0.8160.94
120_V126_S0.8150.93
26_S63_P0.8090.93
72_M76_K0.8080.93
213_D216_G0.8060.93
165_E187_G0.8060.93
136_E142_W0.8040.93
18_E21_G0.7990.93
43_E50_A0.7970.93
99_T223_A0.7960.93
82_V208_A0.7950.93
142_W181_V0.7800.92
6_T108_V0.7780.92
81_A207_I0.7770.92
65_R68_E0.7750.92
120_V186_T0.7750.92
61_I84_V0.7720.92
36_W39_Y0.7720.92
40_A117_F0.7640.91
21_G232_Y0.7600.91
210_K214_D0.7590.91
100_K125_D0.7540.91
76_K194_A0.7540.91
86_D92_T0.7520.90
107_V210_K0.7510.90
228_I231_M0.7480.90
95_L102_R0.7450.90
201_Q205_K0.7370.90
33_L38_D0.7370.90
71_R203_Q0.7330.89
253_G257_V0.7330.89
143_A173_L0.7320.89
156_D175_D0.7300.89
46_Q192_R0.7270.89
59_V104_L0.7230.89
120_V185_Q0.7200.88
39_Y185_Q0.7160.88
3_V56_V0.7150.88
32_D123_N0.7100.88
202_A205_K0.7070.88
127_F226_L0.7060.87
34_N123_N0.7050.87
49_E54_V0.7030.87
33_L72_M0.6980.87
44_A117_F0.6920.86
23_E228_I0.6890.86
134_L181_V0.6890.86
41_V58_A0.6860.86
115_L182_L0.6840.86
115_L160_A0.6810.85
5_V40_A0.6800.85
4_L111_E0.6800.85
123_N126_S0.6780.85
46_Q49_E0.6780.85
252_S256_D0.6720.85
37_D127_F0.6720.85
143_A160_A0.6710.85
84_V215_L0.6710.85
218_D225_S0.6710.85
70_I83_R0.6680.84
106_A216_G0.6650.84
113_P116_V0.6640.84
109_E139_G0.6590.84
224_S228_I0.6560.83
118_S131_G0.6520.83
5_V44_A0.6500.83
12_A32_D0.6450.82
94_L133_A0.6450.82
117_F149_L0.6450.82
37_D125_D0.6440.82
9_E31_Y0.6440.82
245_G251_A0.6420.82
70_I207_I0.6400.82
149_L182_L0.6400.82
42_E49_E0.6380.82
135_A181_V0.6370.81
18_E25_E0.6360.81
227_D230_A0.6360.81
31_Y65_R0.6340.81
235_E238_S0.6330.81
148_D172_E0.6280.81
13_V17_F0.6280.81
122_A127_F0.6260.80
108_V111_E0.6260.80
241_E261_A0.6260.80
36_W126_S0.6210.80
243_I253_G0.6210.80
200_R204_S0.6200.80
196_L203_Q0.6170.79
52_D151_T0.6140.79
165_E185_Q0.6110.79
120_V145_V0.6110.79
41_V45_V0.6100.79
8_K60_T0.6080.78
60_T70_I0.6080.78
47_L115_L0.6070.78
25_E29_L0.6070.78
86_D91_E0.6060.78
37_D69_T0.6030.78
20_S23_E0.6030.78
145_V185_Q0.6020.78
162_V180_A0.5980.77
75_A198_G0.5970.77
141_Q176_V0.5920.77
12_A30_D0.5920.77
95_L225_S0.5900.76
108_V181_V0.5860.76
95_L99_T0.5830.75
62_G73_A0.5820.75
162_V172_E0.5770.75
75_A202_A0.5760.75
3_V6_T0.5760.75
146_V149_L0.5750.75
109_E138_L0.5730.74
108_V140_V0.5710.74
121_Q234_P0.5700.74
61_I104_L0.5690.74
57_V111_E0.5680.74
107_V111_E0.5680.74
164_R173_L0.5670.73
71_R206_E0.5660.73
257_V262_G0.5630.73
21_G25_E0.5630.73
105_A137_T0.5620.73
11_A29_L0.5620.73
61_I95_L0.5610.73
47_L54_V0.5610.73
3_V117_F0.5610.73
121_Q128_G0.5600.73
103_L107_V0.5600.73
132_I183_T0.5580.72
9_E65_R0.5580.72
239_D242_Y0.5550.72
39_Y165_E0.5520.72
50_A151_T0.5510.71
23_E26_S0.5500.71
147_N165_E0.5500.71
41_V184_I0.5490.71
115_L178_L0.5480.71
22_T26_S0.5450.71
110_D214_D0.5440.70
94_L127_F0.5400.70
39_Y186_T0.5390.70
223_A230_A0.5390.70
2_K113_P0.5340.69
71_R207_I0.5330.69
15_D29_L0.5320.69
35_E123_N0.5320.69
206_E256_D0.5310.69
33_L41_V0.5310.69
150_D172_E0.5300.68
127_F224_S0.5300.68
94_L125_D0.5300.68
9_E62_G0.5300.68
126_S142_W0.5290.68
212_L216_G0.5280.68
145_V164_R0.5270.68
83_R207_I0.5270.68
41_V73_A0.5260.68
232_Y235_E0.5230.67
120_V187_G0.5230.67
65_R69_T0.5210.67
79_D205_K0.5200.67
35_E120_V0.5200.67
129_A133_A0.5180.67
100_K127_F0.5180.67
176_V182_L0.5180.67
76_K204_S0.5160.66
23_E230_A0.5110.66
73_A78_A0.5110.66
206_E209_P0.5090.65
128_G145_V0.5090.65
40_A119_G0.5080.65
74_L207_I0.5070.65
164_R167_E0.5060.65
201_Q204_S0.5050.65
45_V56_V0.5040.65
61_I103_L0.5030.64
190_E199_I0.5020.64
26_S85_W0.5020.64
64_E83_R0.5010.64
80_R205_K0.5010.64
99_T218_D0.5000.64
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4l2iB 1 0.9624 100 0.197 Contact Map
1o97C 1 0.906 100 0.201 Contact Map
1efpB 1 0.9098 100 0.23 Contact Map
1efvB 1 0.9323 100 0.25 Contact Map
3ih5A 6 0.7444 100 0.633 Contact Map
4l2iA 1 0.8722 100 0.638 Contact Map
1o97D 1 0.812 100 0.645 Contact Map
1efvA 1 0.8045 99.9 0.683 Contact Map
1efpA 1 0.7857 99.9 0.691 Contact Map
3fetA 2 0.6128 99.9 0.7 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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