Q9HN90 - HALSA - GREMLIN Contacts

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Q9HN90 - Heavy-metal transporting CPx-type ATPase

UniProt:	Q9HN90	Sequences: MTRDSCTLCGLPTPEPPVTGGDDVDGAFCCRGCMEVARTLEDPAAMDDAGAADSLDTGADTTDVDGEAAFLSVSGMHCATCEAFVEAQATDTEGVRAASASYPTETLKVTYDPETVDREAVRAAVDGLGYSATERDGDAAADDDESEVGRLLVGGFFGMMTMLWYVLFLYPAYLDVPSAAQLLDLGGLAGSYLLANVWLMATVVLAYTGYPLFRGAYVSLRAGHPNMDLLVGIAAGAAYVFSTATILTGGREVYFDVAIVVVLAVTVGDYYEGRVKRAAAGRLADLTEERVDDATRRRADGATETVAIEELQAGDEVVVGTGERIPVDGVVTSGSATVDESLVTGESTPVGATPGDDAVGGAVVTDGRLVVAVGDDAASTLDRVVRVLWDVQSARPGVQRLVDRVAAVFVPLVVVLAGVAGGWHLLAGGAAANEALLVGLSVLVVSCPCALGLATPLAVARGVQEALDGGVVVTDVSAFEAAPAVDTVVFDKTGTLTTGEMRVRDVVGDDGVLARAAAVEQYADHPVAAAITDDATPAGDIDDFERVPGRGVAGSLAVRPDGAAAAADAPRVVAGNRALFDDRGWRVPEAYAERAGDARANGNVPVFVGWDGEARGVVVAGDRPRDEWTDVVSTLDADGRDVVVVTGDDPEAAARFRDHDAIAAVFAGVPPEGKTEAVRSLRADGDTVAMVGDGVNDAPALAAADLGVALDHAALAADAADAVVTTEDLGAVPRVFALTDATNGRIRQNLAWAFCYNAIAVPLAVAGVLNPLFAAGAMTVSSLLVVGNSTRSLLDDGVAGP	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	801 (701)
Sequences:	9863 (6514)
Seq/√Len:	246.0

ECOLI - COPA ATZN ATKB
BACSU - COPA CADA ZOSA
HALSA - Q9HN90 Q9HRH2 Q9HSN5
SULSO - Q97UU7 Q97VH4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
650_P	654_A	4.802	1.00
202_T	239_Y	4.181	1.00
641_D	664_A	4.136	1.00
677_A	680_S	3.715	1.00
336_A	369_L	3.633	1.00
570_P	611_D	3.597	1.00
545_E	553_A	3.441	1.00
486_D	686_D	3.390	1.00
330_V	372_A	3.384	1.00
610_W	615_R	3.354	1.00
519_V	554_G	3.350	1.00
682_R	703_A	3.147	1.00
650_P	668_G	3.117	1.00
627_E	728_D	3.101	1.00
316_E	370_V	3.099	1.00
673_G	676_E	3.096	1.00
505_D	603_N	3.055	1.00
543_D	555_S	3.028	1.00
485_V	689_A	3.003	1.00
293_D	305_T	2.943	1.00
550_R	582_D	2.938	1.00
333_S	370_V	2.934	1.00
316_E	332_T	2.924	1.00
295_T	305_T	2.905	1.00
74_S	131_S	2.839	1.00
646_T	653_A	2.759	1.00
534_D	538_A	2.664	1.00
296_R	304_E	2.581	1.00
297_R	370_V	2.544	1.00
512_V	616_G	2.538	1.00
641_D	686_D	2.525	1.00
636_D	663_A	2.489	1.00
679_R	703_A	2.485	1.00
503_V	534_D	2.483	1.00
299_A	302_A	2.458	1.00
654_A	658_D	2.452	1.00
657_R	665_V	2.415	1.00
666_F	677_A	2.377	1.00
372_A	375_D	2.373	1.00
358_A	371_V	2.371	1.00
689_A	708_V	2.369	1.00
573_V	583_R	2.367	1.00
553_A	571_R	2.367	1.00
336_A	364_V	2.344	1.00
629_T	633_S	2.340	1.00
325_I	338_V	2.329	1.00
498_T	623_R	2.324	1.00
570_P	610_W	2.307	1.00
295_T	323_E	2.290	1.00
594_R	597_D	2.231	1.00
327_V	373_V	2.218	1.00
299_A	304_E	2.197	1.00
296_R	299_A	2.195	1.00
246_I	255_F	2.163	1.00
498_T	626_D	2.154	1.00
503_V	618_V	2.154	1.00
162_M	263_L	2.079	1.00
638_D	737_A	2.065	1.00
466_A	738_L	2.049	1.00
580_F	609_G	2.043	1.00
508_G	511_G	2.014	1.00
316_E	372_A	2.013	1.00
572_V	610_W	2.012	1.00
496_L	660_D	2.000	1.00
486_D	687_T	1.999	1.00
595_A	607_F	1.986	1.00
331_V	369_L	1.973	1.00
311_L	327_V	1.966	1.00
547_V	579_L	1.960	1.00
574_A	608_V	1.951	1.00
214_R	218_V	1.943	1.00
489_V	678_V	1.935	1.00
549_G	556_L	1.933	1.00
421_G	439_G	1.925	1.00
630_D	730_G	1.916	1.00
631_V	733_P	1.892	1.00
68_A	110_T	1.888	1.00
236_G	240_V	1.887	1.00
353_T	356_D	1.886	1.00
515_R	572_V	1.877	1.00
332_T	372_A	1.875	1.00
210_Y	214_R	1.873	1.00
420_A	438_V	1.865	1.00
534_D	537_P	1.856	1.00
123_A	127_G	1.849	1.00
751_A	755_C	1.849	1.00
682_R	705_D	1.830	1.00
633_S	637_A	1.827	1.00
117_D	120_A	1.822	1.00
636_D	642_V	1.812	1.00
551_G	556_L	1.811	1.00
745_R	791_R	1.797	1.00
82_E	102_Y	1.795	1.00
126_D	131_S	1.795	1.00
415_V	419_V	1.785	1.00
607_F	614_A	1.781	1.00
643_V	664_A	1.769	1.00
605_P	617_V	1.769	1.00
676_E	679_R	1.768	1.00
311_L	317_V	1.760	1.00
516_A	608_V	1.758	1.00
213_F	236_G	1.745	1.00
122_R	132_A	1.741	1.00
487_T	643_V	1.740	1.00
712_H	727_E	1.738	1.00
297_R	303_T	1.734	1.00
97_A	110_T	1.733	1.00
654_A	665_V	1.731	1.00
645_V	677_A	1.724	1.00
303_T	318_V	1.723	1.00
386_R	390_D	1.722	1.00
680_S	684_D	1.721	1.00
404_R	408_V	1.718	1.00
489_V	681_L	1.702	1.00
299_A	315_D	1.698	1.00
517_A	535_A	1.695	1.00
606_V	620_A	1.679	1.00
296_R	306_V	1.677	1.00
529_A	533_D	1.673	1.00
624_P	660_D	1.672	1.00
489_V	645_V	1.664	1.00
555_S	571_R	1.655	1.00
597_D	601_N	1.647	1.00
634_T	737_A	1.641	1.00
487_T	686_D	1.640	1.00
608_V	616_G	1.640	1.00
675_T	703_A	1.621	1.00
504_R	603_N	1.618	1.00
198_W	243_T	1.591	1.00
544_F	551_G	1.589	1.00
343_V	359_V	1.582	1.00
666_F	680_S	1.578	1.00
331_V	338_V	1.571	1.00
469_G	734_R	1.571	1.00
679_R	683_A	1.569	1.00
576_N	579_L	1.561	1.00
318_V	370_V	1.554	1.00
329_G	371_V	1.552	1.00
295_T	303_T	1.550	1.00
462_G	742_T	1.543	1.00
330_V	374_G	1.543	1.00
644_V	653_A	1.542	1.00
547_V	553_A	1.542	1.00
541_I	556_L	1.542	1.00
78_C	81_C	1.541	1.00
544_F	552_V	1.531	1.00
632_V	642_V	1.526	1.00
233_I	414_V	1.522	1.00
549_G	552_V	1.515	1.00
296_R	315_D	1.512	1.00
629_T	659_H	1.506	1.00
112_D	115_T	1.505	1.00
498_T	502_R	1.504	1.00
630_D	634_T	1.493	1.00
484_A	687_T	1.492	1.00
577_R	581_D	1.486	1.00
335_S	351_G	1.482	1.00
627_E	730_G	1.479	1.00
339_D	365_T	1.477	1.00
679_R	682_R	1.472	1.00
335_S	353_T	1.470	1.00
488_V	689_A	1.468	1.00
423_W	427_A	1.467	1.00
232_G	236_G	1.467	1.00
337_T	351_G	1.463	1.00
511_G	514_A	1.461	1.00
330_V	355_G	1.460	1.00
514_A	568_D	1.457	1.00
465_E	469_G	1.453	1.00
69_A	111_Y	1.437	1.00
598_A	619_V	1.434	1.00
600_A	651_E	1.431	1.00
726_T	731_A	1.415	1.00
580_F	585_W	1.414	1.00
376_D	379_S	1.414	1.00
120_A	123_A	1.414	1.00
340_E	352_A	1.412	1.00
553_A	573_V	1.400	1.00
573_V	579_L	1.399	1.00
357_D	374_G	1.394	1.00
317_V	371_V	1.393	1.00
421_G	425_L	1.376	1.00
520_E	528_A	1.374	1.00
524_D	546_R	1.372	1.00
543_D	551_G	1.372	1.00
531_I	618_V	1.371	1.00
338_V	369_L	1.371	1.00
521_Q	536_T	1.367	1.00
646_T	667_A	1.366	1.00
213_F	232_G	1.365	1.00
544_F	549_G	1.358	1.00
458_A	789_S	1.353	1.00
205_L	213_F	1.352	1.00
745_R	789_S	1.349	1.00
368_R	522_Y	1.345	1.00
154_G	211_P	1.343	1.00
502_R	533_D	1.342	1.00
543_D	549_G	1.340	1.00
96_R	110_T	1.339	1.00
89_A	107_L	1.338	1.00
490_F	496_L	1.325	1.00
502_R	623_R	1.324	1.00
319_V	371_V	1.323	1.00
504_R	621_G	1.323	1.00
496_L	624_P	1.320	1.00
481_A	687_T	1.310	1.00
416_L	765_V	1.309	1.00
90_T	97_A	1.308	1.00
572_V	615_R	1.303	1.00
425_L	432_A	1.301	1.00
490_F	642_V	1.291	1.00
573_V	609_G	1.288	1.00
70_F	106_T	1.288	1.00
297_R	318_V	1.287	1.00
514_A	518_A	1.287	1.00
577_R	607_F	1.282	1.00
519_V	552_V	1.278	1.00
158_G	208_T	1.277	1.00
318_V	368_R	1.277	1.00
638_D	740_D	1.276	1.00
314_G	372_A	1.274	1.00
548_P	551_G	1.274	1.00
465_E	468_D	1.273	1.00
676_E	680_S	1.272	1.00
507_V	594_R	1.270	1.00
431_A	434_E	1.270	1.00
533_D	536_T	1.263	1.00
123_A	126_D	1.260	1.00
74_S	133_T	1.256	1.00
86_E	90_T	1.256	1.00
641_D	663_A	1.254	1.00
204_V	259_I	1.250	1.00
330_V	357_D	1.246	1.00
169_L	172_A	1.244	1.00
124_A	128_L	1.244	1.00
92_T	124_A	1.244	1.00
603_N	619_V	1.238	1.00
592_A	596_G	1.237	1.00
547_V	550_R	1.234	1.00
541_I	554_G	1.232	1.00
159_M	263_L	1.232	1.00
122_R	126_D	1.230	1.00
708_V	732_V	1.225	1.00
551_G	554_G	1.217	1.00
90_T	98_A	1.216	1.00
89_A	98_A	1.212	1.00
501_M	527_V	1.208	1.00
473_V	722_A	1.207	1.00
687_T	705_D	1.206	1.00
591_Y	614_A	1.202	1.00
294_A	326_P	1.200	1.00
295_T	320_G	1.197	1.00
518_A	541_I	1.196	1.00
519_V	572_V	1.192	1.00
89_A	121_V	1.191	1.00
507_V	598_A	1.191	1.00
68_A	108_K	1.191	1.00
572_V	608_V	1.188	1.00
155_G	159_M	1.187	1.00
254_Y	257_V	1.181	1.00
541_I	544_F	1.178	1.00
357_D	375_D	1.177	1.00
92_T	116_V	1.174	1.00
70_F	108_K	1.171	1.00
549_G	554_G	1.168	1.00
748_Q	788_N	1.167	1.00
516_A	618_V	1.164	1.00
664_A	684_D	1.161	1.00
331_V	334_G	1.158	1.00
155_G	267_V	1.153	1.00
483_P	743_N	1.153	1.00
585_W	614_A	1.146	1.00
160_M	164_W	1.146	1.00
96_R	112_D	1.145	1.00
156_F	160_M	1.143	1.00
72_S	135_R	1.140	1.00
542_D	555_S	1.139	1.00
627_E	631_V	1.134	1.00
596_G	600_A	1.133	1.00
634_T	638_D	1.131	1.00
285_D	468_D	1.131	1.00
672_E	676_E	1.130	1.00
506_V	618_V	1.128	1.00
653_A	665_V	1.120	1.00
100_A	107_L	1.119	1.00
624_P	656_F	1.119	1.00
95_V	121_V	1.119	1.00
482_A	706_L	1.117	1.00
506_V	534_D	1.116	1.00
544_F	556_L	1.111	1.00
702_A	719_A	1.108	1.00
408_V	412_L	1.107	1.00
419_V	423_W	1.106	1.00
499_G	622_D	1.105	1.00
743_N	747_R	1.104	1.00
307_A	310_E	1.102	1.00
274_R	278_A	1.089	1.00
239_Y	243_T	1.084	1.00
73_V	76_M	1.084	1.00
556_L	568_D	1.081	1.00
306_V	310_E	1.080	1.00
516_A	574_A	1.080	1.00
333_S	354_P	1.077	1.00
575_G	579_L	1.076	1.00
553_A	583_R	1.074	1.00
297_R	316_E	1.073	1.00
669_V	673_G	1.073	1.00
162_M	165_Y	1.071	1.00
645_V	669_V	1.071	1.00
166_V	260_V	1.070	1.00
634_T	637_A	1.068	1.00
503_V	620_A	1.064	1.00
205_L	236_G	1.061	1.00
73_V	107_L	1.060	1.00
358_A	369_L	1.059	1.00
158_G	164_W	1.055	1.00
164_W	171_P	1.052	1.00
634_T	730_G	1.050	1.00
630_D	633_S	1.046	1.00
422_G	426_L	1.043	1.00
205_L	258_A	1.041	1.00
458_A	745_R	1.041	1.00
519_V	574_A	1.039	1.00
161_T	164_W	1.033	1.00
88_Q	128_L	1.030	1.00
342_L	362_A	1.030	1.00
425_L	435_A	1.029	1.00
482_A	735_V	1.029	1.00
71_L	132_A	1.028	1.00
83_A	87_A	1.028	1.00
741_A	744_G	1.020	1.00
585_W	609_G	1.019	1.00
482_A	736_F	1.016	1.00
217_Y	221_R	1.016	1.00
296_R	317_V	1.014	1.00
194_L	253_V	1.011	1.00
737_A	795_D	1.011	1.00
638_D	736_F	1.010	1.00
89_A	92_T	1.009	1.00
500_E	533_D	1.006	1.00
577_R	592_A	1.006	1.00
149_G	153_V	1.005	1.00
71_L	122_R	1.003	1.00
321_T	546_R	1.003	1.00
517_A	532_T	1.003	1.00
481_A	484_A	1.003	1.00
680_S	683_A	1.000	1.00
414_V	418_G	1.000	1.00
546_R	549_G	0.999	1.00
513_L	534_D	0.998	1.00
550_R	670_P	0.996	1.00
321_T	336_A	0.994	1.00
209_G	262_V	0.992	1.00
488_V	640_R	0.992	1.00
383_R	386_R	0.991	1.00
650_P	667_A	0.985	1.00
512_V	608_V	0.984	1.00
106_T	389_W	0.982	1.00
633_S	636_D	0.978	1.00
610_W	613_E	0.978	1.00
533_D	537_P	0.977	1.00
69_A	118_R	0.976	1.00
556_L	572_V	0.976	1.00
578_A	668_G	0.976	1.00
165_Y	259_I	0.974	1.00
165_Y	169_L	0.972	1.00
317_V	373_V	0.972	1.00
682_R	688_V	0.971	1.00
331_V	356_D	0.970	1.00
321_T	364_V	0.970	1.00
194_L	246_I	0.970	1.00
166_V	169_L	0.968	1.00
198_W	239_Y	0.968	1.00
432_A	436_L	0.967	1.00
788_N	791_R	0.967	1.00
320_G	323_E	0.967	1.00
511_G	570_P	0.966	1.00
488_V	691_V	0.965	1.00
496_L	644_V	0.963	1.00
643_V	677_A	0.960	1.00
481_A	705_D	0.960	1.00
152_L	156_F	0.959	1.00
775_A	779_T	0.955	1.00
550_R	578_A	0.952	1.00
598_A	603_N	0.952	1.00
691_V	732_V	0.948	1.00
760_A	773_F	0.948	1.00
640_R	736_F	0.948	1.00
122_R	134_E	0.947	1.00
675_T	679_R	0.947	1.00
666_F	669_V	0.947	1.00
116_V	120_A	0.947	1.00
487_T	641_D	0.946	1.00
485_V	687_T	0.944	1.00
736_F	740_D	0.944	1.00
312_Q	315_D	0.943	1.00
573_V	585_W	0.943	1.00
170_Y	173_Y	0.943	1.00
527_V	620_A	0.943	1.00
205_L	235_A	0.941	1.00
649_D	668_G	0.940	1.00
632_V	636_D	0.937	1.00
573_V	580_F	0.937	1.00
203_V	207_Y	0.935	1.00
125_V	132_A	0.934	1.00
490_F	732_V	0.933	1.00
542_D	569_A	0.932	1.00
657_R	662_I	0.932	1.00
547_V	551_G	0.932	1.00
731_A	734_R	0.931	1.00
317_V	327_V	0.930	1.00
165_Y	171_P	0.929	1.00
783_L	787_G	0.928	1.00
72_S	133_T	0.927	1.00
423_W	767_G	0.927	1.00
745_R	748_Q	0.927	1.00
612_G	615_R	0.926	1.00
285_D	715_L	0.925	1.00
122_R	131_S	0.925	1.00
505_D	619_V	0.924	1.00
644_V	662_I	0.923	1.00
375_D	378_A	0.922	1.00
319_V	325_I	0.922	1.00
235_A	262_V	0.919	1.00
573_V	612_G	0.916	1.00
649_D	652_A	0.915	1.00
634_T	733_P	0.915	1.00
85_V	128_L	0.914	1.00
305_T	323_E	0.913	1.00
326_P	371_V	0.912	1.00
150_R	154_G	0.910	1.00
308_I	311_L	0.909	1.00
445_V	760_A	0.909	1.00
219_S	226_N	0.907	1.00
190_G	193_L	0.906	1.00
645_V	666_F	0.901	1.00
638_D	733_P	0.900	1.00
650_P	665_V	0.899	1.00
434_E	438_V	0.898	1.00
337_T	366_D	0.893	1.00
325_I	369_L	0.892	1.00
593_E	596_G	0.889	1.00
594_R	598_A	0.888	1.00
438_V	441_S	0.886	1.00
504_R	619_V	0.886	1.00
225_P	229_L	0.885	1.00
73_V	132_A	0.884	1.00
329_G	358_A	0.884	1.00
153_V	157_F	0.881	1.00
475_D	721_D	0.881	1.00
82_E	85_V	0.880	1.00
518_A	540_D	0.879	1.00
634_T	734_R	0.879	1.00
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413_V	761_V	0.874	0.99
261_V	775_A	0.873	0.99
325_I	358_A	0.873	0.99
296_R	311_L	0.872	0.99
507_V	617_V	0.871	0.99
627_E	630_D	0.870	0.99
299_A	306_V	0.870	0.99
709_A	713_A	0.869	0.99
338_V	358_A	0.869	0.99
734_R	795_D	0.868	0.99
279_A	464_Q	0.867	0.99
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86_E	395_R	0.865	0.99
515_R	610_W	0.864	0.99
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502_R	537_P	0.861	0.99
155_G	270_Y	0.861	0.99
496_L	632_V	0.861	0.99
383_R	672_E	0.860	0.99
119_E	123_A	0.857	0.99
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580_F	583_R	0.849	0.99
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505_D	598_A	0.831	0.99
513_L	535_A	0.829	0.99
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216_A	225_P	0.826	0.99
162_M	166_V	0.826	0.99
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421_G	435_A	0.822	0.99
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580_F	584_G	0.819	0.99
435_A	439_G	0.818	0.99
581_D	592_A	0.817	0.99
628_W	632_V	0.816	0.99
722_A	735_V	0.816	0.99
106_T	135_R	0.816	0.99
169_L	173_Y	0.815	0.99
281_G	285_D	0.814	0.99
201_A	259_I	0.814	0.99
88_Q	124_A	0.814	0.99
321_T	524_D	0.813	0.99
165_Y	201_A	0.812	0.99
365_T	529_A	0.811	0.99
571_R	612_G	0.811	0.99
477_S	481_A	0.811	0.99
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621_G	659_H	0.810	0.99
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744_G	748_Q	0.809	0.99
489_V	669_V	0.809	0.99
380_T	672_E	0.809	0.99
741_A	745_R	0.805	0.99
430_A	434_E	0.805	0.99
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400_R	404_R	0.799	0.99
319_V	326_P	0.799	0.99
352_A	356_D	0.798	0.99
360_G	379_S	0.797	0.99
714_A	717_A	0.797	0.99
154_G	158_G	0.795	0.99
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317_V	326_P	0.794	0.99
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709_A	720_A	0.793	0.99
646_T	665_V	0.793	0.99
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579_L	583_R	0.785	0.99
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548_P	556_L	0.773	0.99
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285_D	288_E	0.772	0.99
420_A	439_G	0.772	0.99
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213_F	235_A	0.770	0.99
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257_V	261_V	0.769	0.99
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578_A	581_D	0.765	0.99
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229_L	414_V	0.761	0.99
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599_R	651_E	0.757	0.99
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519_V	608_V	0.756	0.99
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189_A	193_L	0.752	0.98
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656_F	659_H	0.751	0.98
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347_S	652_A	0.751	0.98
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596_G	599_R	0.750	0.98
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541_I	549_G	0.748	0.98
673_G	677_A	0.747	0.98
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763_L	773_F	0.746	0.98
323_E	524_D	0.745	0.98
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601_N	659_H	0.742	0.98
417_A	439_G	0.741	0.98
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415_V	418_G	0.740	0.98
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168_F	172_A	0.737	0.98
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642_V	662_I	0.736	0.98
524_D	544_F	0.735	0.98
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125_V	131_S	0.735	0.98
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655_R	659_H	0.732	0.98
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546_R	551_G	0.724	0.98
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549_G	553_A	0.717	0.98
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226_N	229_L	0.714	0.98
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360_G	380_T	0.709	0.98
162_M	204_V	0.709	0.98
763_L	768_V	0.705	0.98
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158_G	161_T	0.703	0.98
480_E	484_A	0.702	0.98
580_F	607_F	0.701	0.98
488_V	642_V	0.701	0.98
461_R	793_L	0.701	0.98
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165_Y	170_Y	0.697	0.97
277_R	280_A	0.697	0.97
267_V	271_Y	0.695	0.97
458_A	742_T	0.695	0.97
503_V	506_V	0.694	0.97
412_L	416_L	0.692	0.97
111_Y	116_V	0.692	0.97
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541_I	551_G	0.691	0.97
215_G	228_D	0.691	0.97
80_T	83_A	0.690	0.97
206_A	210_Y	0.690	0.97
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319_V	358_A	0.685	0.97
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159_M	163_L	0.682	0.97
316_E	333_S	0.681	0.97
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748_Q	791_R	0.680	0.97
295_T	318_V	0.680	0.97
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313_A	378_A	0.678	0.97
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529_A	532_T	0.676	0.97
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516_A	531_I	0.676	0.97
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171_P	175_D	0.659	0.96
632_V	660_D	0.659	0.96
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294_A	311_L	0.651	0.96
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733_P	736_F	0.639	0.96
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194_L	197_V	0.634	0.96
515_R	615_R	0.633	0.96
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394_A	477_S	0.631	0.96
635_L	640_R	0.630	0.95
689_A	706_L	0.630	0.95
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730_G	733_P	0.628	0.95
334_G	367_G	0.625	0.95
424_H	435_A	0.625	0.95
656_F	660_D	0.624	0.95
755_C	758_A	0.621	0.95
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757_N	778_M	0.619	0.95
284_A	288_E	0.619	0.95
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111_Y	118_R	0.617	0.95
149_G	152_L	0.617	0.95
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417_A	443_L	0.616	0.95
297_R	301_G	0.615	0.95
165_Y	173_Y	0.614	0.95
158_G	169_L	0.613	0.95
231_V	775_A	0.611	0.95
733_P	737_A	0.610	0.95
324_R	339_D	0.609	0.95
90_T	93_E	0.609	0.95
144_D	147_E	0.609	0.95
579_L	606_V	0.608	0.95
151_L	166_V	0.608	0.95
645_V	678_V	0.607	0.94
513_L	517_A	0.607	0.94
386_R	389_W	0.606	0.94
678_V	688_V	0.606	0.94
191_S	194_L	0.606	0.94
576_N	580_F	0.605	0.94
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516_A	534_D	0.603	0.94
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269_D	276_K	0.602	0.94
710_L	717_A	0.602	0.94
778_M	781_S	0.601	0.94
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245_T	252_E	0.601	0.94
483_P	740_D	0.600	0.94
756_Y	784_L	0.600	0.94
536_T	539_G	0.600	0.94
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655_R	658_D	0.599	0.94
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531_I	606_V	0.598	0.94
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162_M	169_L	0.593	0.94
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237_A	440_L	0.592	0.94
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508_G	538_A	0.590	0.94
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522_Y	532_T	0.589	0.94
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780_V	787_G	0.587	0.93
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548_P	552_V	0.587	0.93
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348_T	351_G	0.586	0.93
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83_A	102_Y	0.585	0.93
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724_V	732_V	0.582	0.93
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594_R	617_V	0.581	0.93
241_F	245_T	0.581	0.93
146_S	149_G	0.580	0.93
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603_N	621_G	0.574	0.93
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238_A	258_A	0.572	0.93
158_G	162_M	0.571	0.92
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162_M	173_Y	0.570	0.92
164_W	168_F	0.570	0.92
481_A	706_L	0.570	0.92
331_V	353_T	0.570	0.92
489_V	643_V	0.570	0.92
279_A	457_L	0.569	0.92
148_V	270_Y	0.569	0.92
116_V	121_V	0.569	0.92
76_M	102_Y	0.569	0.92
482_A	689_A	0.569	0.92
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246_I	253_V	0.567	0.92
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490_F	631_V	0.566	0.92
275_V	461_R	0.565	0.92
579_L	585_W	0.565	0.92
164_W	167_L	0.565	0.92
81_C	130_Y	0.565	0.92
92_T	120_A	0.564	0.92
111_Y	117_D	0.564	0.92
402_V	407_A	0.562	0.92
337_T	348_T	0.561	0.92
195_A	203_V	0.561	0.92
84_F	87_A	0.560	0.92
728_D	731_A	0.560	0.92
77_H	102_Y	0.560	0.92
660_D	729_L	0.559	0.92
72_S	132_A	0.558	0.92
429_G	434_E	0.557	0.92
522_Y	541_I	0.557	0.92
398_V	743_N	0.556	0.91
201_A	239_Y	0.556	0.91
86_E	98_A	0.556	0.91
319_V	329_G	0.555	0.91
394_A	679_R	0.555	0.91
297_R	368_R	0.555	0.91
70_F	135_R	0.554	0.91
599_R	649_D	0.554	0.91
331_V	352_A	0.554	0.91
334_G	369_L	0.554	0.91
260_V	264_A	0.553	0.91
401_L	754_F	0.553	0.91
143_D	147_E	0.553	0.91
216_A	232_G	0.553	0.91
519_V	556_L	0.552	0.91
71_L	107_L	0.552	0.91
89_A	95_V	0.552	0.91
336_A	366_D	0.551	0.91
614_A	617_V	0.551	0.91
611_D	615_R	0.550	0.91
76_M	105_E	0.550	0.91
104_T	389_W	0.550	0.91
314_G	330_V	0.549	0.91
77_H	81_C	0.548	0.91
556_L	570_P	0.547	0.91
87_A	91_D	0.547	0.91
129_G	134_E	0.547	0.91
150_R	153_V	0.547	0.91
628_W	729_L	0.547	0.91
516_A	616_G	0.546	0.91
157_F	160_M	0.546	0.91
430_A	435_A	0.545	0.91
412_L	415_V	0.544	0.91
79_A	82_E	0.544	0.91
664_A	677_A	0.541	0.90
306_V	327_V	0.541	0.90
546_R	556_L	0.540	0.90
82_E	100_A	0.538	0.90
157_F	164_W	0.537	0.90
487_T	688_V	0.535	0.90
776_G	780_V	0.534	0.90
578_A	670_P	0.534	0.90
211_P	266_T	0.533	0.90
425_L	429_G	0.533	0.90
118_R	132_A	0.533	0.90
220_L	223_G	0.532	0.90
488_V	635_L	0.532	0.90
588_P	591_Y	0.531	0.90
690_M	760_A	0.531	0.90
155_G	162_M	0.530	0.89
641_D	684_D	0.530	0.89
575_G	609_G	0.529	0.89
500_E	529_A	0.529	0.89
581_D	584_G	0.529	0.89
601_N	619_V	0.528	0.89
93_E	96_R	0.528	0.89
402_V	750_L	0.527	0.89
366_D	369_L	0.527	0.89
105_E	276_K	0.527	0.89
555_S	569_A	0.527	0.89
271_Y	457_L	0.526	0.89
459_V	480_E	0.525	0.89
119_E	122_R	0.525	0.89
156_F	166_V	0.524	0.89
198_W	247_L	0.524	0.89
664_A	686_D	0.524	0.89
243_T	255_F	0.523	0.89
95_V	98_A	0.523	0.89
205_L	240_V	0.523	0.89
488_V	708_V	0.523	0.89
186_G	189_A	0.523	0.89
742_T	788_N	0.522	0.89
394_A	475_D	0.522	0.89
741_A	748_Q	0.521	0.89
188_L	191_S	0.521	0.89
333_S	542_D	0.520	0.89
407_A	411_P	0.520	0.89
217_Y	229_L	0.520	0.89
319_V	369_L	0.520	0.89
157_F	161_T	0.519	0.88
598_A	601_N	0.519	0.88
542_D	551_G	0.519	0.88
377_A	382_D	0.518	0.88
170_Y	174_L	0.518	0.88
201_A	258_A	0.518	0.88
201_A	205_L	0.518	0.88
540_D	568_D	0.518	0.88
84_F	128_L	0.517	0.88
164_W	172_A	0.517	0.88
78_C	102_Y	0.516	0.88
486_D	688_V	0.516	0.88
651_E	654_A	0.516	0.88
162_M	260_V	0.516	0.88
474_T	718_D	0.515	0.88
69_A	109_V	0.515	0.88
71_L	109_V	0.514	0.88
94_G	116_V	0.514	0.88
85_V	89_A	0.514	0.88
486_D	641_D	0.514	0.88
282_R	464_Q	0.513	0.88
519_V	541_I	0.513	0.88
80_T	84_F	0.512	0.88
148_V	151_L	0.511	0.88
245_T	251_R	0.511	0.88
359_V	380_T	0.511	0.88
779_T	783_L	0.511	0.88
79_A	102_Y	0.511	0.88
245_T	249_G	0.510	0.88
157_F	166_V	0.510	0.88
109_V	118_R	0.510	0.88
304_E	307_A	0.510	0.88
757_N	781_S	0.509	0.88
421_G	438_V	0.509	0.88
445_V	777_A	0.509	0.88
516_A	535_A	0.509	0.88
308_I	327_V	0.509	0.88
152_L	155_G	0.508	0.87
579_L	582_D	0.508	0.87
707_G	719_A	0.508	0.87
437_L	440_L	0.508	0.87
73_V	105_E	0.508	0.87
579_L	609_G	0.507	0.87
489_V	677_A	0.507	0.87
342_L	360_G	0.506	0.87
147_E	150_R	0.506	0.87
579_L	607_F	0.506	0.87
598_A	605_P	0.505	0.87
458_A	462_G	0.505	0.87
418_G	421_G	0.505	0.87
423_W	766_A	0.505	0.87
437_L	441_S	0.505	0.87
112_D	116_V	0.505	0.87
88_Q	125_V	0.504	0.87
171_P	174_L	0.504	0.87
120_A	124_A	0.504	0.87
155_G	169_L	0.503	0.87
445_V	764_A	0.503	0.87
590_A	594_R	0.502	0.87
390_D	393_S	0.502	0.87
550_R	576_N	0.501	0.87
147_E	151_L	0.501	0.87
604_V	649_D	0.500	0.87
81_C	102_Y	0.500	0.87

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3j09A	2	0.8752	100	0.263	Contact Map
4bbjA	1	0.7903	100	0.267	Contact Map
4umwA	1	0.7378	100	0.283	Contact Map
3j08A	2	0.7778	100	0.335	Contact Map
3b8cA	1	0.7765	100	0.495	Contact Map
1mhsA	2	0.8439	100	0.501	Contact Map
3ixzA	1	0.8052	100	0.518	Contact Map
2zxeA	1	0.799	100	0.519	Contact Map
3ar4A	1	0.7853	100	0.528	Contact Map
3skxA	1	0.3146	100	0.799	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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