Q9HN85 - HALSA - GREMLIN Contacts

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Q9HN85 - Phosphomannomutase

UniProt:	Q9HN85	Sequences: MNVFGSSGTRGVANEELTPGFVLRVAKAAGSVWRADRVAVARDTRTTGRMLENAAVAGLQSIGVDVDRLGVVPTPATQAYAERAGVPAVMVTASHNPSQYNGVKLVGSDGVELAVADLERVERAFTTEQFDNAAWDGVGADREVASAGRDYRAQLSDAVDRAAIAAADLTVALDPGHGAGALTSPTFYRELGCDVVTVNAQPDGHFPGREPEPVREHLGDLGALVRAADADVGIAHDGDADRAIFVDETGEYIEGDATLAALAEAELDAGDTTVSAVNVSQRLVDVCDRTGATLELTPIGSTQIMTRIRELEAEGDHVPVAGEGNGGIIFPEYRMTRDGAYTGARFLELLADGTPASEVVAPYDDYHNVRVNVDYDTEAQRGALLDAAEARALDADADRTTIDGYRLDYGDAWVLVRPSGTEPVVRIYAESTDHERAESLAEAFAADLRAARADA	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	455 (437)
Sequences:	10907 (6690)
Seq/√Len:	320.0

ECOLI - MANB PGM GLMM
BACSU - GLMM PGCA
HALSA - Q9HN85 Q9HR19 Q9HN30
SULSO - Q980S1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
224_L	228_A	4.147	1.00
307_R	310_E	4.126	1.00
180_G	240_A	3.793	1.00
172_A	230_A	3.576	1.00
223_A	227_A	3.396	1.00
248_E	357_S	3.288	1.00
170_T	194_D	2.851	1.00
156_S	190_E	2.850	1.00
46_T	205_H	2.844	1.00
27_K	62_I	2.836	1.00
224_L	227_A	2.737	1.00
284_V	296_L	2.708	1.00
37_R	65_D	2.699	1.00
434_H	438_E	2.667	1.00
272_T	293_T	2.665	1.00
295_E	307_R	2.646	1.00
83_R	150_D	2.628	1.00
186_T	190_E	2.551	1.00
31_S	124_A	2.537	1.00
289_R	362_P	2.457	1.00
52_E	68_R	2.451	1.00
264_E	290_T	2.444	1.00
149_R	153_A	2.413	1.00
219_G	223_A	2.329	1.00
236_H	343_G	2.312	1.00
354_T	358_E	2.288	1.00
38_V	59_L	2.272	1.00
19_P	50_M	2.256	1.00
222_G	226_R	2.243	1.00
26_A	55_A	2.238	1.00
245_F	346_F	2.186	1.00
55_A	89_V	2.182	1.00
170_T	196_V	2.169	1.00
40_V	56_V	2.155	1.00
59_L	89_V	2.149	1.00
41_A	77_T	2.127	1.00
197_T	200_A	2.104	1.00
442_E	446_A	2.098	1.00
29_A	87_P	2.073	1.00
285_D	288_D	2.059	1.00
386_D	390_A	2.056	1.00
433_D	436_R	2.031	1.00
267_L	292_A	2.024	1.00
30_G	59_L	2.021	1.00
39_A	86_V	2.005	1.00
42_R	52_E	2.001	1.00
264_E	362_P	2.000	1.00
42_R	48_G	1.990	1.00
49_R	53_N	1.974	1.00
12_V	99_Q	1.969	1.00
30_G	62_I	1.960	1.00
264_E	268_D	1.959	1.00
123_R	127_T	1.944	1.00
172_A	224_L	1.937	1.00
438_E	442_E	1.925	1.00
124_A	127_T	1.896	1.00
120_R	123_R	1.869	1.00
31_S	62_I	1.856	1.00
284_V	288_D	1.823	1.00
199_N	220_D	1.807	1.00
79_A	83_R	1.803	1.00
307_R	316_D	1.762	1.00
37_R	67_D	1.751	1.00
152_R	187_F	1.750	1.00
149_R	186_T	1.746	1.00
261_A	349_L	1.735	1.00
285_D	366_Y	1.731	1.00
12_V	100_Y	1.722	1.00
436_R	439_S	1.722	1.00
113_L	121_V	1.719	1.00
29_A	105_L	1.709	1.00
234_I	343_G	1.695	1.00
27_K	31_S	1.682	1.00
196_V	228_A	1.681	1.00
23_L	54_A	1.657	1.00
287_C	292_A	1.653	1.00
122_E	126_T	1.597	1.00
356_A	360_V	1.588	1.00
429_A	441_A	1.533	1.00
439_S	443_A	1.526	1.00
225_V	233_G	1.524	1.00
12_V	15_E	1.523	1.00
185_P	189_R	1.516	1.00
175_P	200_A	1.505	1.00
223_A	226_R	1.505	1.00
186_T	189_R	1.502	1.00
153_A	190_E	1.497	1.00
306_T	310_E	1.496	1.00
389_E	401_T	1.485	1.00
248_E	355_P	1.474	1.00
437_A	441_A	1.473	1.00
435_E	439_S	1.459	1.00
23_L	57_A	1.447	1.00
22_V	103_V	1.441	1.00
369_V	438_E	1.441	1.00
185_P	200_A	1.441	1.00
23_L	61_S	1.435	1.00
59_L	64_V	1.432	1.00
272_T	295_E	1.427	1.00
446_A	449_R	1.426	1.00
275_S	294_L	1.417	1.00
32_V	117_D	1.409	1.00
149_R	190_E	1.395	1.00
204_G	207_P	1.385	1.00
220_D	223_A	1.383	1.00
44_T	71_V	1.383	1.00
445_A	449_R	1.376	1.00
297_T	307_R	1.374	1.00
22_V	51_L	1.372	1.00
171_V	232_V	1.370	1.00
39_A	80_Y	1.368	1.00
262_L	330_F	1.360	1.00
383_A	387_A	1.358	1.00
79_A	154_Q	1.354	1.00
251_E	361_A	1.350	1.00
221_L	235_A	1.346	1.00
304_I	321_A	1.343	1.00
13_A	47_T	1.338	1.00
30_G	64_V	1.334	1.00
219_G	222_G	1.322	1.00
441_A	445_A	1.314	1.00
42_R	49_R	1.314	1.00
32_V	124_A	1.303	1.00
387_A	391_R	1.303	1.00
9_T	25_V	1.302	1.00
46_T	204_G	1.297	1.00
221_L	246_V	1.296	1.00
259_L	322_G	1.295	1.00
26_A	103_V	1.294	1.00
431_S	437_A	1.286	1.00
403_D	406_R	1.286	1.00
249_T	357_S	1.279	1.00
170_T	228_A	1.273	1.00
56_V	60_Q	1.269	1.00
123_R	126_T	1.268	1.00
263_A	273_T	1.258	1.00
282_R	359_V	1.253	1.00
358_E	361_A	1.250	1.00
169_L	231_D	1.241	1.00
232_V	347_L	1.237	1.00
155_L	341_Y	1.236	1.00
226_R	249_T	1.225	1.00
32_V	120_R	1.220	1.00
438_E	441_A	1.218	1.00
386_D	389_E	1.217	1.00
158_A	345_R	1.212	1.00
355_P	358_E	1.212	1.00
42_R	68_R	1.210	1.00
232_V	350_L	1.208	1.00
72_V	76_A	1.205	1.00
191_L	344_A	1.202	1.00
310_E	316_D	1.200	1.00
59_L	66_V	1.200	1.00
170_T	229_D	1.198	1.00
155_L	344_A	1.190	1.00
150_D	153_A	1.190	1.00
293_T	316_D	1.173	1.00
154_Q	157_D	1.171	1.00
26_A	59_L	1.168	1.00
40_V	55_A	1.159	1.00
268_D	352_D	1.149	1.00
146_S	149_R	1.147	1.00
153_A	157_D	1.144	1.00
148_G	183_T	1.144	1.00
148_G	186_T	1.124	1.00
260_A	282_R	1.124	1.00
220_D	224_L	1.118	1.00
275_S	279_V	1.117	1.00
234_I	245_F	1.114	1.00
139_G	142_R	1.109	1.00
352_D	355_P	1.108	1.00
120_R	124_A	1.105	1.00
38_V	87_P	1.100	1.00
222_G	252_Y	1.095	1.00
89_V	103_V	1.092	1.00
52_E	56_V	1.092	1.00
218_L	252_Y	1.092	1.00
160_D	348_E	1.090	1.00
56_V	68_R	1.090	1.00
81_A	88_A	1.084	1.00
173_L	188_Y	1.084	1.00
83_R	154_Q	1.077	1.00
371_V	445_A	1.077	1.00
188_Y	343_G	1.076	1.00
267_L	271_D	1.076	1.00
275_S	296_L	1.071	1.00
119_E	122_E	1.070	1.00
369_V	441_A	1.070	1.00
371_V	442_E	1.068	1.00
29_A	89_V	1.067	1.00
79_A	150_D	1.067	1.00
286_V	290_T	1.067	1.00
379_A	383_A	1.065	1.00
9_T	105_L	1.064	1.00
295_E	316_D	1.064	1.00
198_V	220_D	1.063	1.00
405_Y	440_L	1.059	1.00
152_R	183_T	1.058	1.00
436_R	440_L	1.057	1.00
198_V	224_L	1.054	1.00
117_D	120_R	1.054	1.00
152_R	190_E	1.054	1.00
84_A	147_A	1.053	1.00
260_A	286_V	1.052	1.00
77_T	88_A	1.051	1.00
19_P	54_A	1.051	1.00
73_P	76_A	1.044	1.00
180_G	236_H	1.041	1.00
54_A	58_G	1.038	1.00
55_A	91_V	1.037	1.00
247_D	251_E	1.032	1.00
21_F	25_V	1.031	1.00
279_V	283_L	1.024	1.00
77_T	90_M	1.023	1.00
388_A	416_V	1.023	1.00
41_A	90_M	1.022	1.00
154_Q	158_A	1.017	1.00
177_H	209_R	1.013	1.00
284_V	294_L	1.012	1.00
225_V	246_V	1.011	1.00
196_V	230_A	1.007	1.00
196_V	224_L	1.006	1.00
267_L	290_T	1.005	1.00
382_G	386_D	1.005	1.00
27_K	61_S	1.005	1.00
181_A	200_A	1.002	1.00
189_R	197_T	1.002	1.00
114_A	117_D	1.001	1.00
407_L	414_V	1.001	1.00
55_A	59_L	0.997	1.00
188_Y	347_L	0.997	1.00
173_L	180_G	0.994	1.00
44_T	202_P	0.992	1.00
199_N	213_P	0.990	1.00
107_G	117_D	0.988	1.00
181_A	185_P	0.982	1.00
259_L	283_L	0.980	1.00
221_L	233_G	0.978	1.00
47_T	50_M	0.976	1.00
287_C	294_L	0.975	1.00
303_Q	306_T	0.974	1.00
406_R	413_W	0.972	1.00
173_L	236_H	0.968	1.00
153_A	156_S	0.966	1.00
403_D	407_L	0.966	1.00
69_L	72_V	0.966	1.00
308_I	318_V	0.964	1.00
28_A	125_F	0.962	1.00
57_A	61_S	0.958	1.00
432_T	436_R	0.957	1.00
257_A	365_D	0.955	1.00
350_L	359_V	0.955	1.00
28_A	124_A	0.951	1.00
115_V	303_Q	0.949	1.00
52_E	91_V	0.946	1.00
134_A	137_G	0.943	1.00
218_L	244_I	0.943	1.00
65_D	143_E	0.942	1.00
119_E	123_R	0.942	1.00
172_A	196_V	0.941	1.00
53_N	57_A	0.941	1.00
442_E	445_A	0.938	1.00
285_D	289_R	0.937	1.00
257_A	360_V	0.932	1.00
116_A	120_R	0.929	1.00
330_F	345_R	0.927	1.00
170_T	231_D	0.924	1.00
60_Q	141_D	0.922	1.00
272_T	316_D	0.919	1.00
48_G	101_N	0.919	1.00
33_W	87_P	0.918	1.00
272_T	318_V	0.917	1.00
317_H	331_P	0.914	1.00
377_T	380_Q	0.914	1.00
156_S	191_L	0.912	1.00
258_T	346_F	0.908	1.00
177_H	199_N	0.902	1.00
320_V	328_I	0.902	1.00
118_L	121_V	0.902	1.00
171_V	193_C	0.895	1.00
151_Y	155_L	0.892	1.00
273_T	287_C	0.891	1.00
289_R	363_Y	0.890	1.00
169_L	350_L	0.888	1.00
203_D	211_P	0.885	1.00
184_S	236_H	0.885	1.00
286_V	289_R	0.883	1.00
39_A	69_L	0.882	1.00
172_A	228_A	0.878	1.00
174_D	221_L	0.877	1.00
259_L	273_T	0.875	1.00
67_D	86_V	0.875	1.00
41_A	72_V	0.873	1.00
273_T	283_L	0.872	1.00
380_Q	383_A	0.872	1.00
26_A	58_G	0.870	1.00
138_V	142_R	0.867	1.00
42_R	71_V	0.867	1.00
258_T	328_I	0.866	1.00
243_A	342_T	0.866	1.00
25_V	125_F	0.864	1.00
147_A	150_D	0.856	1.00
162_A	167_A	0.856	1.00
234_I	243_A	0.853	1.00
183_T	340_A	0.852	1.00
268_D	290_T	0.851	1.00
171_V	347_L	0.851	1.00
400_T	408_D	0.849	1.00
375_Y	378_E	0.848	1.00
184_S	340_A	0.848	1.00
80_Y	147_A	0.847	1.00
442_E	449_R	0.847	1.00
19_P	23_L	0.844	1.00
70_G	182_L	0.843	1.00
245_F	258_T	0.842	1.00
113_L	117_D	0.840	1.00
345_R	348_E	0.836	1.00
222_G	246_V	0.836	1.00
266_E	345_R	0.834	1.00
271_D	317_H	0.831	1.00
427_I	445_A	0.830	1.00
373_V	445_A	0.830	1.00
435_E	438_E	0.829	1.00
122_E	125_F	0.829	1.00
134_A	138_V	0.829	1.00
271_D	292_A	0.826	1.00
288_D	294_L	0.821	1.00
383_A	386_D	0.819	1.00
265_A	349_L	0.819	1.00
35_A	124_A	0.819	1.00
246_V	252_Y	0.815	1.00
81_A	87_P	0.814	1.00
35_A	120_R	0.810	1.00
169_L	347_L	0.809	1.00
148_G	182_L	0.809	1.00
37_R	86_V	0.807	1.00
72_V	90_M	0.806	1.00
83_R	147_A	0.805	1.00
188_Y	193_C	0.802	1.00
391_R	394_D	0.801	1.00
135_W	138_V	0.799	1.00
328_I	342_T	0.799	1.00
260_A	280_S	0.797	1.00
261_A	360_V	0.797	1.00
221_L	225_V	0.796	1.00
354_T	362_P	0.796	1.00
234_I	347_L	0.795	1.00
236_H	339_G	0.793	1.00
26_A	30_G	0.791	1.00
429_A	437_A	0.791	1.00
274_V	307_R	0.791	1.00
71_V	179_A	0.791	1.00
152_R	186_T	0.789	1.00
130_F	133_A	0.788	1.00
264_E	286_V	0.785	1.00
275_S	284_V	0.785	1.00
274_V	321_A	0.785	1.00
216_E	219_G	0.782	1.00
20_G	24_R	0.781	1.00
41_A	69_L	0.781	1.00
387_A	390_A	0.781	1.00
80_Y	84_A	0.778	1.00
298_P	303_Q	0.777	1.00
44_T	179_A	0.776	1.00
440_L	443_A	0.775	1.00
57_A	132_N	0.773	1.00
146_S	150_D	0.772	1.00
411_D	432_T	0.771	1.00
118_L	122_E	0.769	1.00
264_E	363_Y	0.768	1.00
243_A	339_G	0.767	1.00
262_L	345_R	0.765	0.99
169_L	232_V	0.764	0.99
280_S	322_G	0.763	0.99
398_D	408_D	0.761	0.99
408_D	443_A	0.761	0.99
390_A	393_L	0.758	0.99
347_L	350_L	0.758	0.99
251_E	257_A	0.757	0.99
168_D	194_D	0.756	0.99
225_V	230_A	0.755	0.99
54_A	57_A	0.753	0.99
271_D	319_P	0.752	0.99
388_A	392_A	0.750	0.99
319_P	332_E	0.750	0.99
244_I	252_Y	0.748	0.99
431_S	436_R	0.748	0.99
159_V	344_A	0.743	0.99
305_M	329_I	0.742	0.99
7_S	276_A	0.741	0.99
105_L	121_V	0.740	0.99
39_A	84_A	0.739	0.99
258_T	262_L	0.738	0.99
226_R	229_D	0.733	0.99
277_V	415_L	0.733	0.99
60_Q	142_R	0.732	0.99
327_G	337_R	0.731	0.99
401_T	404_G	0.730	0.99
288_D	293_T	0.729	0.99
5_G	8_G	0.727	0.99
67_D	145_A	0.727	0.99
367_H	433_D	0.726	0.99
149_R	152_R	0.725	0.99
145_A	149_R	0.725	0.99
56_V	66_V	0.724	0.99
218_L	246_V	0.723	0.99
400_T	404_G	0.723	0.99
385_L	389_E	0.723	0.99
132_N	135_W	0.722	0.99
177_H	213_P	0.722	0.99
281_Q	430_E	0.721	0.99
356_A	359_V	0.721	0.99
283_L	322_G	0.720	0.99
414_V	444_F	0.718	0.99
173_L	184_S	0.717	0.99
182_L	186_T	0.717	0.99
6_S	420_G	0.715	0.99
69_L	76_A	0.715	0.99
154_Q	333_Y	0.715	0.99
290_T	363_Y	0.715	0.99
262_L	349_L	0.713	0.99
172_A	198_V	0.713	0.99
154_Q	334_R	0.713	0.99
24_R	125_F	0.708	0.99
167_A	194_D	0.707	0.99
56_V	141_D	0.698	0.99
185_P	197_T	0.696	0.99
76_A	148_G	0.692	0.99
247_D	357_S	0.691	0.99
406_R	415_L	0.690	0.99
267_L	287_C	0.690	0.99
373_V	449_R	0.690	0.99
443_A	447_D	0.688	0.99
251_E	360_V	0.688	0.99
172_A	233_G	0.687	0.99
232_V	245_F	0.687	0.99
138_V	141_D	0.686	0.99
152_R	156_S	0.685	0.99
26_A	89_V	0.683	0.99
259_L	320_V	0.679	0.99
136_D	139_G	0.679	0.99
354_T	359_V	0.678	0.99
32_V	121_V	0.677	0.99
95_H	104_K	0.676	0.99
93_A	96_N	0.676	0.99
31_S	127_T	0.675	0.99
443_A	446_A	0.673	0.99
384_L	387_A	0.670	0.99
369_V	445_A	0.670	0.99
98_S	205_H	0.670	0.99
379_A	418_P	0.668	0.99
198_V	223_A	0.668	0.99
396_D	400_T	0.668	0.99
69_L	77_T	0.667	0.99
253_I	356_A	0.667	0.99
375_Y	380_Q	0.666	0.99
111_V	309_R	0.665	0.99
381_R	385_L	0.665	0.99
14_N	18_T	0.664	0.99
128_E	131_D	0.663	0.99
31_S	131_D	0.662	0.99
48_G	52_E	0.662	0.99
15_E	99_Q	0.661	0.99
372_N	424_V	0.661	0.99
181_A	202_P	0.657	0.98
133_A	138_V	0.655	0.98
29_A	33_W	0.652	0.98
367_H	434_H	0.651	0.98
46_T	98_S	0.650	0.98
84_A	150_D	0.650	0.98
243_A	343_G	0.647	0.98
401_T	405_Y	0.647	0.98
169_L	351_A	0.643	0.98
385_L	418_P	0.641	0.98
22_V	54_A	0.640	0.98
262_L	342_T	0.638	0.98
23_L	58_G	0.638	0.98
349_L	352_D	0.637	0.98
281_Q	366_Y	0.635	0.98
7_S	370_R	0.634	0.98
137_G	140_A	0.634	0.98
67_D	144_V	0.631	0.98
263_A	283_L	0.631	0.98
433_D	437_A	0.629	0.98
389_E	393_L	0.628	0.98
436_R	443_A	0.628	0.98
12_V	16_E	0.627	0.98
233_G	246_V	0.627	0.98
14_N	50_M	0.626	0.98
72_V	148_G	0.626	0.98
260_A	363_Y	0.625	0.98
379_A	382_G	0.624	0.98
256_D	368_N	0.623	0.98
188_Y	192_G	0.618	0.98
282_R	366_Y	0.617	0.98
50_M	54_A	0.616	0.98
18_T	21_F	0.615	0.98
218_L	221_L	0.615	0.98
148_G	152_R	0.614	0.98
374_D	424_V	0.614	0.98
109_D	309_R	0.613	0.98
184_S	343_G	0.612	0.98
278_N	299_I	0.612	0.98
346_F	356_A	0.610	0.98
224_L	230_A	0.610	0.98
116_A	119_E	0.609	0.97
375_Y	381_R	0.608	0.97
283_L	294_L	0.607	0.97
195_V	200_A	0.607	0.97
253_I	261_A	0.607	0.97
271_D	293_T	0.605	0.97
439_S	442_E	0.605	0.97
263_A	320_V	0.605	0.97
94_S	104_K	0.604	0.97
295_E	318_V	0.603	0.97
416_V	448_L	0.603	0.97
444_F	447_D	0.603	0.97
49_R	70_G	0.603	0.97
281_Q	408_D	0.602	0.97
29_A	38_V	0.602	0.97
121_V	125_F	0.599	0.97
24_R	128_E	0.599	0.97
184_S	188_Y	0.596	0.97
113_L	118_L	0.594	0.97
135_W	139_G	0.594	0.97
96_N	421_T	0.593	0.97
231_D	248_E	0.593	0.97
17_L	25_V	0.593	0.97
440_L	444_F	0.592	0.97
404_G	407_L	0.592	0.97
36_D	108_S	0.592	0.97
412_A	440_L	0.592	0.97
17_L	22_V	0.590	0.97
320_V	330_F	0.590	0.97
376_D	379_A	0.590	0.97
265_A	352_D	0.589	0.97
60_Q	66_V	0.588	0.97
24_R	126_T	0.588	0.97
380_Q	384_L	0.588	0.97
57_A	60_Q	0.588	0.97
275_S	281_Q	0.587	0.97
375_Y	418_P	0.587	0.97
21_F	125_F	0.586	0.97
437_A	440_L	0.585	0.97
7_S	112_E	0.585	0.97
159_V	166_A	0.585	0.97
371_V	441_A	0.581	0.97
25_V	105_L	0.580	0.97
274_V	297_T	0.579	0.97
96_N	100_Y	0.579	0.97
5_G	420_G	0.578	0.97
175_P	198_V	0.578	0.97
38_V	64_V	0.578	0.97
22_V	26_A	0.576	0.96
17_L	21_F	0.576	0.96
434_H	437_A	0.574	0.96
162_A	166_A	0.574	0.96
226_R	251_E	0.574	0.96
68_R	143_E	0.573	0.96
441_A	444_F	0.573	0.96
170_T	230_A	0.571	0.96
350_L	356_A	0.569	0.96
413_W	430_E	0.569	0.96
274_V	304_I	0.568	0.96
199_N	212_E	0.566	0.96
281_Q	285_D	0.564	0.96
11_G	16_E	0.563	0.96
22_V	55_A	0.562	0.96
83_R	153_A	0.562	0.96
226_R	250_G	0.559	0.96
371_V	449_R	0.558	0.96
55_A	103_V	0.558	0.96
19_P	57_A	0.557	0.96
53_N	138_V	0.556	0.96
251_E	365_D	0.555	0.96
24_R	27_K	0.554	0.96
184_S	195_V	0.554	0.96
155_L	158_A	0.553	0.96
378_E	382_G	0.553	0.96
10_R	95_H	0.552	0.96
262_L	346_F	0.552	0.96
172_A	221_L	0.552	0.96
330_F	342_T	0.551	0.95
211_P	215_R	0.550	0.95
174_D	235_A	0.548	0.95
243_A	346_F	0.545	0.95
211_P	214_V	0.544	0.95
249_T	361_A	0.544	0.95
203_D	207_P	0.543	0.95
65_D	140_A	0.541	0.95
395_A	398_D	0.541	0.95
181_A	195_V	0.540	0.95
129_Q	134_A	0.540	0.95
187_F	190_E	0.539	0.95
151_Y	338_D	0.539	0.95
173_L	195_V	0.538	0.95
258_T	326_G	0.537	0.95
409_Y	412_A	0.537	0.95
78_Q	335_M	0.537	0.95
260_A	264_E	0.537	0.95
167_A	231_D	0.537	0.95
357_S	361_A	0.536	0.95
251_E	357_S	0.536	0.95
266_E	319_P	0.536	0.95
81_A	86_V	0.536	0.95
21_F	24_R	0.534	0.95
187_F	340_A	0.534	0.95
209_R	217_H	0.534	0.95
285_D	432_T	0.534	0.95
138_V	143_E	0.533	0.95
23_L	27_K	0.533	0.95
360_V	363_Y	0.532	0.95
330_F	341_Y	0.531	0.95
27_K	130_F	0.530	0.94
412_A	431_S	0.530	0.94
248_E	358_E	0.529	0.94
235_A	246_V	0.527	0.94
76_A	183_T	0.527	0.94
168_D	351_A	0.526	0.94
286_V	363_Y	0.524	0.94
96_N	104_K	0.524	0.94
218_L	233_G	0.522	0.94
402_I	416_V	0.522	0.94
416_V	427_I	0.521	0.94
444_F	448_L	0.521	0.94
115_V	118_L	0.518	0.94
218_L	222_G	0.518	0.94
95_H	241_D	0.516	0.94
301_S	337_R	0.516	0.94
374_D	422_E	0.515	0.94
13_A	51_L	0.515	0.94
138_V	144_V	0.515	0.94
218_L	235_A	0.513	0.93
189_R	194_D	0.513	0.93
189_R	192_G	0.513	0.93
384_L	425_V	0.512	0.93
254_E	257_A	0.512	0.93
158_A	341_Y	0.511	0.93
36_D	120_R	0.511	0.93
106_V	112_E	0.510	0.93
39_A	88_A	0.510	0.93
253_I	360_V	0.508	0.93
37_R	84_A	0.508	0.93
412_A	436_R	0.508	0.93
215_R	252_Y	0.506	0.93
408_D	439_S	0.506	0.93
188_Y	236_H	0.505	0.93
131_D	134_A	0.504	0.93
376_D	380_Q	0.504	0.93
59_L	87_P	0.504	0.93
168_D	193_C	0.503	0.93
202_P	206_F	0.503	0.93
310_E	317_H	0.503	0.93
184_S	192_G	0.502	0.93
283_L	287_C	0.500	0.93
278_N	428_Y	0.500	0.93

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1wqaA	3	0.978	100	0.086	Contact Map
2f7lA	4	0.978	100	0.087	Contact Map
1tuoA	1	0.9143	100	0.132	Contact Map
3pdkA	2	0.9495	100	0.141	Contact Map
1p5dX	1	0.9648	100	0.148	Contact Map
3uw2A	1	0.9516	100	0.151	Contact Map
3i3wA	2	0.9473	100	0.154	Contact Map
3na5A	2	0.9758	100	0.17	Contact Map
2z0fA	2	0.9319	100	0.173	Contact Map
4hjhA	2	0.956	100	0.186	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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