GREMLIN Database
SYL - Leucine--tRNA ligase
UniProt: Q9HN72 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 885 (774)
Sequences: 3625 (1911)
Seq/√Len: 68.7

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
143_E146_D5.2991.00
769_N772_G4.8351.00
240_H315_E4.4101.00
770_P774_D4.2091.00
21_D114_E4.0061.00
203_D207_D3.9841.00
314_A355_R3.8031.00
18_R22_D3.7871.00
434_S476_A3.6321.00
236_P249_V3.6141.00
234_E249_V3.5451.00
302_E306_T3.4731.00
19_E23_A3.2661.00
760_D780_E3.2151.00
702_T725_G3.2071.00
389_D392_T3.1371.00
510_T514_N3.0971.00
500_S503_F3.0671.00
747_A763_D3.0651.00
388_L396_E2.9591.00
24_D123_E2.8721.00
178_L185_P2.7651.00
8_D11_A2.7281.00
210_D224_R2.6281.00
145_R429_I2.6181.00
203_D229_R2.6141.00
236_P247_D2.5951.00
67_R72_E2.5691.00
211_E552_R2.5571.00
664_F711_I2.5201.00
154_A190_D2.5141.00
27_R123_E2.5061.00
309_N312_T2.5001.00
24_D27_R2.4871.00
208_G541_K2.4771.00
246_E275_A2.4661.00
248_V266_L2.4191.00
271_P326_S2.3791.00
100_E104_R2.3671.00
82_S129_C2.3571.00
514_N550_E2.3381.00
506_A509_D2.3371.00
143_E442_D2.3211.00
108_Q111_D2.3041.00
470_T477_P2.2981.00
73_D515_D2.2901.00
775_V779_P2.2571.00
259_H384_D2.2561.00
179_C182_C2.2121.00
306_T315_E2.2091.00
80_W110_R2.2021.00
764_T773_V2.1861.00
107_D110_R2.1831.00
261_A316_I2.1791.00
503_F506_A2.1781.00
201_Y545_D2.1771.00
207_D229_R2.1711.00
110_R125_E2.1521.00
142_T439_S2.1411.00
569_G577_D2.1411.00
80_W125_E2.1401.00
402_D405_A2.1271.00
655_A744_H2.1211.00
509_D512_R2.0981.00
749_S763_D2.0901.00
468_Q479_V2.0901.00
162_S184_T2.0861.00
307_A318_V2.0831.00
276_A305_F2.0801.00
289_E299_Q2.0791.00
356_Q380_V2.0741.00
34_D72_E2.0701.00
341_D345_E2.0511.00
440_V444_D2.0241.00
69_M706_K2.0231.00
441_P444_D2.0201.00
160_C182_C2.0161.00
471_C474_C2.0101.00
396_E399_A2.0091.00
650_A699_R2.0071.00
234_E405_A2.0021.00
771_T774_D1.9871.00
705_V729_V1.9861.00
653_T700_G1.9531.00
430_V469_T1.9451.00
384_D400_D1.9441.00
774_D778_A1.9401.00
274_E287_V1.9401.00
499_A517_L1.9391.00
429_I437_P1.9331.00
339_H357_V1.9331.00
432_C435_C1.9321.00
659_A675_A1.9311.00
760_D782_M1.9301.00
652_E656_T1.9191.00
435_C474_C1.9181.00
238_T247_D1.9161.00
348_Q354_V1.9141.00
658_Q737_P1.9001.00
395_E406_S1.8961.00
768_E773_V1.8961.00
372_A375_A1.8941.00
772_G775_V1.8881.00
70_D661_T1.8851.00
17_Q714_H1.8701.00
622_L712_A1.8611.00
154_A192_D1.8561.00
204_E544_A1.8541.00
160_C179_C1.8451.00
390_S394_R1.8271.00
266_L273_A1.8201.00
235_V258_I1.8101.00
432_C474_C1.8091.00
155_A195_F1.8081.00
540_T551_H1.8081.00
417_V485_M1.7971.00
787_A792_A1.7931.00
137_N425_T1.7831.00
359_A378_V1.7701.00
782_M785_V1.7701.00
231_D406_S1.7691.00
702_T706_K1.7681.00
658_Q662_T1.7621.00
196_F489_L1.7541.00
544_A552_R1.7471.00
622_L715_V1.7391.00
383_G386_T1.7341.00
66_Y70_D1.7151.00
749_S761_I1.7141.00
432_C471_C1.7001.00
758_V761_I1.6971.00
661_T734_W1.6931.00
229_R408_V1.6871.00
235_V401_I1.6871.00
258_I401_I1.6810.99
750_L773_V1.6800.99
452_F463_A1.6740.99
385_Y400_D1.6720.99
297_E349_A1.6690.99
658_Q739_R1.6640.99
536_S555_F1.6640.99
280_D284_A1.6560.99
402_D406_S1.6520.99
162_S182_C1.6460.99
29_P512_R1.6460.99
219_V560_T1.6370.99
650_A741_V1.6360.99
584_R587_D1.6350.99
435_C471_C1.6220.99
60_T523_V1.6200.99
208_G211_E1.6170.99
248_V264_F1.6150.99
740_D743_D1.6140.99
283_V320_V1.6120.99
233_V398_T1.6070.99
157_V166_V1.6060.99
464_E468_Q1.5980.99
283_V301_V1.5920.99
759_R786_L1.5900.99
440_V447_V1.5900.99
286_F299_Q1.5870.99
288_E291_A1.5840.99
261_A333_L1.5780.99
147_A546_L1.5670.99
311_A400_D1.5630.99
152_R192_D1.5610.99
160_C184_T1.5570.99
314_A353_P1.5530.99
467_K479_V1.5460.99
507_P548_M1.5440.99
137_N490_D1.5440.99
146_D442_D1.5410.99
398_T406_S1.5410.99
751_I761_I1.5380.99
703_A707_L1.5350.99
495_F540_T1.5330.99
542_A546_L1.5330.99
344_H354_V1.5300.99
432_C436_G1.5220.99
657_V707_L1.5130.99
568_D577_D1.5090.99
381_N386_T1.5090.99
197_E200_A1.5030.99
162_S179_C1.4980.99
231_D408_V1.4940.99
436_G474_C1.4690.99
698_A702_T1.4690.99
203_D410_Y1.4630.99
179_C184_T1.4610.99
285_H289_E1.4600.99
308_T315_E1.4580.99
508_F513_A1.4580.99
652_E655_A1.4580.99
706_K732_A1.4530.99
628_M680_V1.4430.98
657_V703_A1.4410.98
705_V719_C1.4320.98
468_Q477_P1.4310.98
14_Q18_R1.4310.98
103_E130_D1.4290.98
234_E407_A1.4190.98
235_V250_A1.4180.98
433_E477_P1.4130.98
651_R744_H1.4100.98
15_H718_E1.4080.98
264_F316_I1.3990.98
356_Q359_A1.3920.98
204_E208_G1.3890.98
126_I498_F1.3820.98
448_E451_E1.3800.98
653_T703_A1.3780.98
152_R431_H1.3770.98
344_H348_Q1.3750.98
432_C438_V1.3690.98
429_I439_S1.3680.98
767_I772_G1.3640.98
282_D285_H1.3560.98
385_Y397_L1.3450.98
104_R107_D1.3450.98
359_A380_V1.3380.97
19_E721_T1.3340.97
66_Y661_T1.3340.97
207_D210_D1.3280.97
469_T478_A1.3270.97
303_T320_V1.3230.97
596_L712_A1.3230.97
567_E577_D1.3220.97
751_I758_V1.3130.97
110_R114_E1.3110.97
783_Y786_L1.3110.97
737_P742_S1.3090.97
705_V723_L1.3050.97
782_M786_L1.3040.97
600_R677_D1.3040.97
255_V398_T1.3030.97
391_E394_R1.3010.97
652_E682_L1.2980.97
754_T786_L1.2940.97
674_Q678_E1.2930.97
570_T576_K1.2900.97
585_I594_A1.2700.96
506_A510_T1.2670.96
727_G732_A1.2570.96
203_D231_D1.2520.96
142_T442_D1.2480.96
647_E746_R1.2470.96
432_C472_P1.2450.96
26_F730_A1.2390.96
703_A706_K1.2380.96
709_A716_A1.2360.96
433_E479_V1.2350.96
399_A406_S1.2340.96
395_E399_A1.2320.96
626_L715_V1.2280.96
656_T660_A1.2270.96
30_D33_D1.2260.96
280_D301_V1.2260.96
54_V116_L1.2190.96
625_L708_L1.2140.95
40_A76_H1.2110.95
259_H400_D1.2110.95
683_L700_G1.2030.95
136_W139_W1.2000.95
779_P784_D1.1980.95
425_T490_D1.1940.95
593_T615_V1.1940.95
463_A467_K1.1900.95
238_T403_G1.1900.95
99_R103_E1.1890.95
675_A678_E1.1890.95
302_E305_F1.1850.95
258_I311_A1.1850.95
150_V196_F1.1830.95
143_E546_L1.1820.95
436_G471_C1.1790.95
288_E292_D1.1790.95
241_T244_G1.1730.95
100_E451_E1.1700.94
432_C478_A1.1680.94
9_H619_H1.1650.94
341_D372_A1.1650.94
200_A203_D1.1640.94
146_D473_D1.1620.94
764_T768_E1.1620.94
570_T577_D1.1580.94
10_H587_D1.1490.94
435_C438_V1.1490.94
510_T550_E1.1440.94
289_E292_D1.1440.94
628_M701_V1.1420.94
161_P187_T1.1420.94
653_T657_V1.1390.94
567_E570_T1.1360.94
145_R437_P1.1350.93
629_A701_V1.1340.93
15_H721_T1.1330.93
99_R451_E1.1330.93
619_H623_E1.1320.93
36_E67_R1.1310.93
511_Q514_N1.1300.93
785_V788_R1.1260.93
496_L517_L1.1230.93
373_Y377_G1.1210.93
396_E400_D1.1200.93
625_L704_A1.1160.93
163_C182_C1.1150.93
435_C472_P1.1150.93
35_P515_D1.1140.93
241_T245_D1.1140.93
185_P292_D1.1120.93
752_E762_V1.1100.93
273_A277_A1.1070.93
771_T775_V1.1070.93
219_V526_D1.1050.93
709_A729_V1.1030.92
273_A320_V1.1010.92
203_D408_V1.1010.92
142_T429_I1.1000.92
360_P363_D1.0980.92
67_R70_D1.0970.92
789_A794_G1.0960.92
16_W718_E1.0960.92
376_D391_E1.0950.92
163_C179_C1.0930.92
115_A587_D1.0930.92
588_E616_R1.0930.92
341_D344_H1.0930.92
161_P184_T1.0900.92
768_E776_V1.0880.92
68_R119_G1.0870.92
433_E476_A1.0850.92
218_N526_D1.0840.92
452_F465_D1.0830.92
708_L716_A1.0830.92
63_F521_E1.0820.92
649_V686_Y1.0810.92
220_R224_R1.0800.92
472_P478_A1.0800.92
649_V683_L1.0750.92
233_V401_I1.0710.91
279_R282_D1.0670.91
144_F539_V1.0630.91
394_R397_L1.0590.91
262_T355_R1.0580.91
778_A792_A1.0570.91
680_V684_V1.0570.91
467_K482_T1.0560.91
235_V255_V1.0560.91
360_P373_Y1.0510.91
143_E548_M1.0510.91
139_W442_D1.0500.91
163_C184_T1.0480.90
717_E728_F1.0450.90
762_V773_V1.0440.90
659_A663_H1.0430.90
790_K794_G1.0430.90
430_V478_A1.0420.90
602_A608_F1.0420.90
277_A305_F1.0390.90
438_V474_C1.0380.90
764_T776_V1.0370.90
676_V704_A1.0350.90
173_E176_D1.0340.90
375_A390_S1.0310.90
680_V704_A1.0310.90
373_Y376_D1.0270.90
311_A397_L1.0260.89
683_L704_A1.0260.89
787_A790_K1.0260.89
368_V371_A1.0240.89
284_A288_E1.0240.89
440_V443_D1.0220.89
255_V394_R1.0210.89
64_A119_G1.0190.89
132_D504_D1.0180.89
663_H671_R1.0180.89
720_W724_G1.0160.89
255_V397_L1.0160.89
265_A321_A1.0080.89
378_V389_D1.0070.89
463_A466_W1.0060.89
358_V379_L1.0050.89
559_T605_S1.0050.89
513_A550_E1.0050.89
630_R722_A1.0040.88
380_V386_T1.0030.88
160_C183_D1.0030.88
474_C478_A1.0020.88
131_P448_E1.0010.88
204_E541_K0.9990.88
344_H363_D0.9980.88
87_A101_W0.9950.88
236_P405_A0.9910.88
781_W784_D0.9900.88
358_V373_Y0.9900.88
738_D741_V0.9850.87
770_P775_V0.9840.87
70_D736_T0.9830.87
19_E25_V0.9820.87
438_V478_A0.9800.87
768_E772_G0.9790.87
762_V780_E0.9780.87
569_G579_G0.9770.87
743_D766_G0.9760.87
597_F601_A0.9740.87
312_T315_E0.9740.87
139_W143_E0.9730.87
358_V390_S0.9720.87
19_E728_F0.9700.87
259_H311_A0.9700.87
565_L577_D0.9670.87
284_A287_V0.9670.87
285_H288_E0.9640.86
583_E587_D0.9610.86
321_A350_H0.9610.86
144_F542_A0.9600.86
656_T707_L0.9580.86
147_A542_A0.9580.86
239_V244_G0.9540.86
379_L390_S0.9530.86
173_E180_W0.9510.86
653_T696_V0.9500.86
274_E284_A0.9500.86
132_D502_A0.9480.85
629_A705_V0.9470.85
160_C167_L0.9460.85
754_T777_T0.9460.85
708_L712_A0.9460.85
58_A599_L0.9450.85
281_D285_H0.9440.85
276_A303_T0.9430.85
40_A60_T0.9420.85
372_A377_G0.9410.85
127_T130_D0.9400.85
239_V245_D0.9390.85
365_D368_V0.9380.85
500_S509_D0.9380.85
392_T396_E0.9380.85
266_L276_A0.9370.85
765_A768_E0.9370.85
182_C185_P0.9340.85
33_D36_E0.9340.85
660_A672_A0.9320.84
251_F409_Q0.9300.84
500_S512_R0.9300.84
772_G776_V0.9270.84
16_W717_E0.9250.84
188_E294_D0.9190.84
299_Q322_D0.9180.84
48_Q108_Q0.9130.83
366_A369_E0.9100.83
93_E577_D0.9100.83
565_L568_D0.9070.83
435_C478_A0.9070.83
283_V287_V0.9050.83
156_T188_E0.9040.83
438_V471_C0.9040.83
311_A401_I0.9030.83
379_L385_Y0.9020.82
103_E107_D0.9020.82
55_R608_F0.8990.82
367_D370_A0.8980.82
152_R437_P0.8980.82
25_V730_A0.8970.82
208_G552_R0.8970.82
240_H308_T0.8970.82
216_P219_V0.8970.82
139_W548_M0.8930.82
388_L393_A0.8930.82
173_E178_L0.8920.82
286_F322_D0.8920.82
286_F290_V0.8910.82
69_M733_A0.8890.82
248_V332_A0.8890.82
502_A512_R0.8880.81
63_F667_M0.8880.81
305_F318_V0.8880.81
90_A101_W0.8880.81
499_A512_R0.8870.81
672_A676_V0.8870.81
559_T608_F0.8870.81
760_D777_T0.8860.81
435_C473_D0.8840.81
38_V64_A0.8840.81
287_V291_A0.8830.81
629_A719_C0.8830.81
649_V682_L0.8820.81
395_E398_T0.8800.81
60_T76_H0.8800.81
751_I762_V0.8800.81
593_T619_H0.8790.81
727_G731_E0.8770.81
279_R283_V0.8760.81
500_S508_F0.8760.81
705_V716_A0.8750.80
314_A383_G0.8730.80
97_N451_E0.8720.80
265_A335_A0.8710.80
495_F549_L0.8710.80
398_T402_D0.8690.80
217_S221_D0.8690.80
469_T472_P0.8690.80
432_C476_A0.8680.80
338_A356_Q0.8640.80
559_T667_M0.8630.80
565_L569_G0.8620.79
540_T549_L0.8610.79
391_E395_E0.8610.79
111_D115_A0.8590.79
235_V252_T0.8570.79
650_A654_A0.8570.79
35_P520_D0.8560.79
748_T766_G0.8560.79
264_F333_L0.8540.79
379_L393_A0.8510.79
654_A657_V0.8510.79
774_D793_D0.8500.79
566_G577_D0.8500.79
517_L551_H0.8500.79
492_S495_F0.8500.79
273_A287_V0.8440.78
239_V318_V0.8440.78
776_V780_E0.8440.78
142_T145_R0.8420.78
584_R588_E0.8410.78
784_D787_A0.8400.78
272_L275_A0.8390.78
160_C185_P0.8390.78
463_A468_Q0.8370.77
239_V246_E0.8360.77
770_P773_V0.8340.77
589_Y616_R0.8330.77
754_T787_A0.8330.77
458_N461_D0.8320.77
25_V728_F0.8320.77
42_F555_F0.8310.77
80_W127_T0.8310.77
62_A664_F0.8300.77
321_A333_L0.8290.77
213_D220_R0.8280.77
471_C476_A0.8270.77
436_G472_P0.8260.77
156_T190_D0.8260.77
145_R439_S0.8220.76
144_F546_L0.8220.76
746_R766_G0.8200.76
179_C183_D0.8200.76
579_G583_E0.8180.76
702_T724_G0.8170.76
399_A402_D0.8160.76
625_L628_M0.8160.76
716_A729_V0.8150.76
160_C163_C0.8150.76
557_G667_M0.8140.75
126_I130_D0.8140.75
471_C478_A0.8130.75
163_C183_D0.8130.75
69_M709_A0.8120.75
249_V405_A0.8110.75
353_P356_Q0.8060.75
656_T675_A0.8040.75
625_L712_A0.8040.75
790_K793_D0.8040.75
42_F531_M0.8020.74
96_T100_E0.8000.74
778_A784_D0.8000.74
221_D224_R0.7990.74
485_M489_L0.7990.74
338_A354_V0.7980.74
80_W114_E0.7970.74
495_F517_L0.7970.74
712_A715_V0.7970.74
425_T489_L0.7970.74
299_Q350_H0.7960.74
412_L531_M0.7950.74
709_A728_F0.7950.74
627_S631_A0.7940.74
40_A523_V0.7920.73
642_L696_V0.7920.73
754_T758_V0.7920.73
178_L182_C0.7920.73
233_V255_V0.7910.73
19_E22_D0.7900.73
728_F731_E0.7880.73
338_A344_H0.7880.73
750_L764_T0.7860.73
765_A772_G0.7860.73
259_H309_N0.7860.73
643_D646_A0.7850.73
372_A390_S0.7840.73
754_T783_Y0.7840.73
564_V602_A0.7840.73
513_A551_H0.7820.72
379_L384_D0.7820.72
397_L400_D0.7810.72
385_Y390_S0.7800.72
129_C487_T0.7780.72
198_T534_L0.7780.72
171_Q486_D0.7780.72
564_V608_F0.7770.72
508_F543_F0.7740.72
206_L229_R0.7740.72
541_K552_R0.7740.72
126_I133_Y0.7730.72
659_A678_E0.7730.72
42_F498_F0.7720.72
262_T352_L0.7710.71
34_D67_R0.7700.71
672_A711_I0.7700.71
374_T377_G0.7690.71
662_T666_D0.7660.71
653_T679_L0.7650.71
366_A370_A0.7650.71
435_C476_A0.7640.71
397_L401_I0.7630.71
721_T726_D0.7630.71
470_T476_A0.7630.71
781_W785_V0.7610.70
132_D448_E0.7610.70
90_A94_R0.7590.70
754_T782_M0.7590.70
319_V352_L0.7580.70
499_A513_A0.7550.70
267_A287_V0.7550.70
188_E291_A0.7550.70
66_Y665_D0.7540.70
469_T477_P0.7530.70
712_A716_A0.7520.70
155_A193_Q0.7500.69
264_F335_A0.7490.69
567_E579_G0.7490.69
277_A283_V0.7470.69
264_F307_A0.7470.69
430_V440_V0.7470.69
373_Y390_S0.7460.69
148_G197_E0.7460.69
644_P699_R0.7440.69
273_A276_A0.7440.69
750_L762_V0.7430.69
596_L618_S0.7430.69
309_N316_I0.7420.69
430_V444_D0.7410.68
566_G569_G0.7410.68
235_V264_F0.7400.68
778_A787_A0.7380.68
664_F672_A0.7370.68
469_T476_A0.7360.68
567_E580_V0.7350.68
209_L220_R0.7350.68
107_D114_E0.7340.68
21_D24_D0.7340.68
244_G275_A0.7330.68
324_V333_L0.7320.67
485_M490_D0.7320.67
384_D397_L0.7320.67
277_A280_D0.7310.67
358_V377_G0.7300.67
431_H479_V0.7300.67
323_F335_A0.7290.67
109_M113_F0.7290.67
649_V700_G0.7280.67
204_E552_R0.7270.67
96_T101_W0.7270.67
739_R742_S0.7260.67
179_C185_P0.7260.67
430_V474_C0.7260.67
762_V776_V0.7250.67
754_T760_D0.7250.67
199_T202_A0.7240.67
302_E315_E0.7230.66
500_S506_A0.7230.66
249_V407_A0.7210.66
302_E319_V0.7210.66
137_N485_M0.7200.66
472_P476_A0.7190.66
379_L397_L0.7190.66
497_R500_S0.7170.66
56_N120_Y0.7170.66
180_W457_G0.7160.66
213_D557_G0.7160.66
250_A333_L0.7150.66
778_A793_D0.7140.66
559_T604_P0.7120.65
103_E127_T0.7120.65
301_V320_V0.7120.65
489_L539_V0.7110.65
265_A324_V0.7100.65
646_A686_Y0.7100.65
240_H306_T0.7090.65
376_D389_D0.7080.65
40_A56_N0.7070.65
308_T312_T0.7070.65
106_I127_T0.7060.65
497_R501_P0.7060.65
432_C469_T0.7050.65
461_D479_V0.7050.65
496_L543_F0.7030.64
393_A397_L0.7030.64
261_A335_A0.7010.64
709_A730_A0.7010.64
187_T288_E0.7010.64
56_N560_T0.7000.64
211_E556_A0.7000.64
791_A794_G0.6990.64
155_A416_G0.6990.64
733_A736_T0.6990.64
699_R703_A0.6980.64
173_E183_D0.6980.64
508_F550_E0.6980.64
780_E783_Y0.6980.64
531_M534_L0.6970.64
267_A290_V0.6970.64
362_G370_A0.6970.64
178_L183_D0.6960.64
706_K709_A0.6960.64
7_Y13_E0.6950.63
263_Y319_V0.6950.63
775_V778_A0.6950.63
361_A378_V0.6940.63
660_A676_V0.6930.63
434_S473_D0.6920.63
266_L332_A0.6910.63
438_V472_P0.6900.63
624_R684_V0.6890.63
116_L586_V0.6870.63
787_A791_A0.6860.62
307_A316_I0.6860.62
68_R731_E0.6840.62
356_Q360_P0.6840.62
780_E784_D0.6840.62
594_A615_V0.6830.62
51_M54_V0.6830.62
431_H436_G0.6830.62
152_R483_D0.6820.62
379_L386_T0.6810.62
621_F680_V0.6810.62
170_E531_M0.6800.62
14_Q115_A0.6790.62
273_A305_F0.6790.62
82_S127_T0.6770.61
702_T723_L0.6770.61
597_F614_G0.6760.61
625_L705_V0.6750.61
250_A264_F0.6740.61
233_V406_S0.6720.61
376_D394_R0.6710.61
776_V779_P0.6710.61
752_E783_Y0.6700.61
160_C178_L0.6700.61
167_L179_C0.6690.60
261_A309_N0.6690.60
647_E747_A0.6690.60
338_A355_R0.6680.60
173_E530_V0.6680.60
765_A769_N0.6680.60
648_Y682_L0.6670.60
311_A403_G0.6670.60
164_E182_C0.6660.60
59_I604_P0.6650.60
585_I593_T0.6650.60
503_F509_D0.6650.60
496_L540_T0.6650.60
51_M598_T0.6640.60
385_Y396_E0.6640.60
212_L215_W0.6630.60
356_Q363_D0.6630.60
286_F301_V0.6620.60
430_V471_C0.6620.60
430_V472_P0.6620.60
277_A320_V0.6620.60
171_Q488_F0.6620.60
613_E616_R0.6610.60
371_A375_A0.6600.59
706_K725_G0.6590.59
303_T306_T0.6590.59
178_L184_T0.6570.59
127_T498_F0.6570.59
234_E330_T0.6550.59
260_G336_V0.6540.59
761_I785_V0.6540.59
117_G714_H0.6530.59
356_Q361_A0.6520.59
617_S620_T0.6520.59
673_V711_I0.6520.59
762_V777_T0.6510.58
382_A386_T0.6480.58
430_V441_P0.6470.58
140_L543_F0.6460.58
469_T474_C0.6460.58
269_D323_F0.6460.58
488_F531_M0.6460.58
748_T751_I0.6430.57
787_A793_D0.6420.57
519_V555_F0.6410.57
565_L607_A0.6410.57
26_F709_A0.6410.57
11_A15_H0.6400.57
570_T579_G0.6400.57
231_D395_E0.6400.57
653_T656_T0.6400.57
241_T246_E0.6400.57
31_D34_D0.6400.57
275_A278_D0.6390.57
788_R794_G0.6380.57
662_T665_D0.6380.57
751_I773_V0.6370.57
146_D229_R0.6370.57
483_D487_T0.6370.57
357_V361_A0.6370.57
80_W106_I0.6370.57
616_R620_T0.6360.57
153_R195_F0.6360.57
63_F67_R0.6360.57
366_A371_A0.6360.57
379_L389_D0.6350.57
581_A584_R0.6340.56
130_D502_A0.6340.56
129_C488_F0.6340.56
75_L124_R0.6340.56
30_D34_D0.6340.56
269_D326_S0.6330.56
655_A741_V0.6330.56
743_D746_R0.6330.56
746_R767_I0.6330.56
287_V290_V0.6330.56
339_H356_Q0.6310.56
436_G478_A0.6300.56
344_H356_Q0.6300.56
341_D374_T0.6270.56
298_P345_E0.6260.55
255_V258_I0.6260.55
240_H244_G0.6260.55
339_H344_H0.6260.55
59_I599_L0.6260.55
755_R790_K0.6250.55
486_D490_D0.6250.55
752_E780_E0.6250.55
431_H438_V0.6250.55
215_W558_L0.6250.55
649_V679_L0.6240.55
457_G462_A0.6230.55
377_G382_A0.6230.55
348_Q351_D0.6220.55
266_L305_F0.6220.55
137_N489_L0.6220.55
60_T120_Y0.6220.55
654_A699_R0.6220.55
344_H369_E0.6220.55
760_D784_D0.6210.55
48_Q583_E0.6200.55
173_E179_C0.6190.55
290_V322_D0.6190.55
230_T328_V0.6190.55
33_D73_D0.6170.54
38_V63_F0.6160.54
417_V486_D0.6160.54
70_D734_W0.6140.54
78_M122_W0.6140.54
454_H462_A0.6140.54
365_D369_E0.6140.54
23_A728_F0.6130.54
195_F488_F0.6130.54
657_V737_P0.6130.54
207_D410_Y0.6120.54
384_D396_E0.6120.54
645_A648_Y0.6120.54
93_E162_S0.6100.54
56_N76_H0.6100.54
296_D322_D0.6090.53
701_V705_V0.6080.53
183_D570_T0.6080.53
357_V379_L0.6070.53
203_D206_L0.6070.53
75_L516_W0.6070.53
173_E531_M0.6070.53
181_R492_S0.6070.53
94_R101_W0.6060.53
239_V307_A0.6040.53
660_A707_L0.6040.53
28_V515_D0.6030.53
749_S762_V0.6030.53
676_V707_L0.6030.53
320_V333_L0.6030.53
645_A699_R0.6020.53
464_E467_K0.6020.53
187_T291_A0.6020.53
509_D514_N0.6010.52
657_V661_T0.6000.52
281_D284_A0.5990.52
303_T319_V0.5990.52
140_L431_H0.5980.52
789_A792_A0.5980.52
267_A326_S0.5970.52
10_H14_Q0.5970.52
625_L716_A0.5960.52
192_D483_D0.5960.52
339_H379_L0.5960.52
461_D467_K0.5950.52
240_H245_D0.5940.52
530_V536_S0.5930.52
172_V531_M0.5930.52
25_V731_E0.5920.51
162_S183_D0.5920.51
96_T104_R0.5920.51
680_V685_R0.5920.51
55_R62_A0.5920.51
48_Q104_R0.5910.51
754_T785_V0.5910.51
543_F548_M0.5910.51
476_A479_V0.5900.51
430_V435_C0.5890.51
416_G490_D0.5890.51
55_R59_I0.5890.51
431_H437_P0.5890.51
238_T245_D0.5880.51
705_V708_L0.5870.51
430_V447_V0.5870.51
93_E181_R0.5870.51
654_A742_S0.5860.51
425_T539_V0.5860.51
359_A362_G0.5850.51
365_D370_A0.5850.51
309_N383_G0.5840.50
112_Q582_P0.5840.50
59_I608_F0.5840.50
290_V299_Q0.5820.50
123_E502_A0.5820.50
204_E545_D0.5810.50
359_A363_D0.5810.50
150_V418_S0.5810.50
294_D323_F0.5810.50
385_Y398_T0.5810.50
702_T720_W0.5800.50
251_F408_V0.5800.50
147_A545_D0.5800.50
280_D283_V0.5800.50
360_P367_D0.5800.50
89_N182_C0.5790.50
644_P648_Y0.5790.50
462_A466_W0.5780.50
650_A700_G0.5780.50
487_T531_M0.5780.50
743_D784_D0.5770.50
115_A585_I0.5760.49
432_C473_D0.5760.49
115_A586_V0.5760.49
717_E730_A0.5750.49
351_D505_D0.5750.49
573_S578_N0.5750.49
472_P477_P0.5740.49
137_N416_G0.5740.49
312_T400_D0.5730.49
241_T275_A0.5730.49
521_E559_T0.5730.49
440_V469_T0.5720.49
35_P723_L0.5700.49
726_D775_V0.5690.49
630_R633_N0.5690.49
697_V700_G0.5680.49
255_V264_F0.5680.49
333_L350_H0.5680.49
487_T540_T0.5670.48
648_Y685_R0.5670.48
495_F551_H0.5660.48
69_M732_A0.5660.48
286_F293_P0.5660.48
221_D225_N0.5660.48
42_F128_T0.5650.48
646_A696_V0.5650.48
496_L549_L0.5640.48
392_T395_E0.5630.48
773_V776_V0.5630.48
375_A378_V0.5630.48
760_D783_Y0.5610.48
367_D371_A0.5610.48
210_D213_D0.5610.48
394_R398_T0.5600.48
198_T531_M0.5590.47
762_V768_E0.5590.47
599_L607_A0.5580.47
11_A14_Q0.5570.47
135_K139_W0.5570.47
58_A591_A0.5550.47
752_E760_D0.5550.47
639_D642_L0.5550.47
262_T347_A0.5530.47
54_V118_F0.5530.47
518_P551_H0.5530.47
338_A357_V0.5520.47
485_M496_L0.5520.47
632_V701_V0.5520.47
376_D390_S0.5520.47
413_R534_L0.5510.46
651_R654_A0.5500.46
611_S614_G0.5490.46
784_D788_R0.5480.46
278_D282_D0.5480.46
78_M118_F0.5480.46
10_H115_A0.5470.46
31_D35_P0.5470.46
747_A765_A0.5470.46
751_I755_R0.5470.46
162_S187_T0.5460.46
89_N184_T0.5460.46
142_T146_D0.5460.46
659_A662_T0.5450.46
608_F615_V0.5450.46
362_G371_A0.5450.46
36_E63_F0.5440.46
171_Q487_T0.5440.46
287_V320_V0.5440.46
622_L708_L0.5430.46
379_L394_R0.5430.46
286_F350_H0.5430.46
40_A64_A0.5420.45
257_T336_V0.5410.45
44_Y87_A0.5410.45
149_L197_E0.5410.45
274_E280_D0.5400.45
191_L607_A0.5400.45
425_T486_D0.5390.45
62_A608_F0.5390.45
19_E717_E0.5390.45
68_R759_R0.5380.45
568_D579_G0.5380.45
488_F492_S0.5380.45
316_I333_L0.5380.45
664_F783_Y0.5370.45
124_R501_P0.5370.45
306_T318_V0.5370.45
222_M529_A0.5370.45
89_N163_C0.5370.45
625_L680_V0.5360.45
56_N483_D0.5360.45
363_D368_V0.5360.45
417_V488_F0.5360.45
512_R515_D0.5360.45
659_A671_R0.5350.45
501_P504_D0.5350.45
748_T767_I0.5340.44
752_E776_V0.5340.44
140_L489_L0.5330.44
526_D560_T0.5330.44
12_I622_L0.5330.44
774_D794_G0.5320.44
331_G340_D0.5320.44
85_L131_P0.5320.44
565_L570_T0.5320.44
54_V582_P0.5320.44
486_D489_L0.5310.44
651_R655_A0.5310.44
338_A341_D0.5300.44
564_V601_A0.5300.44
760_D786_L0.5290.44
531_M536_S0.5290.44
101_W109_M0.5290.44
508_F548_M0.5290.44
503_F507_P0.5290.44
261_A321_A0.5290.44
150_V429_I0.5280.44
56_N60_T0.5280.44
344_H371_A0.5280.44
149_L518_P0.5280.44
470_T475_G0.5270.44
676_V680_V0.5270.44
147_A151_D0.5270.44
238_T308_T0.5270.44
632_V636_A0.5260.44
256_D394_R0.5260.44
39_L498_F0.5260.44
282_D289_E0.5260.44
107_D111_D0.5260.44
499_A515_D0.5250.43
642_L646_A0.5240.43
57_Y80_W0.5240.43
777_T786_L0.5240.43
605_S667_M0.5240.43
788_R793_D0.5230.43
417_V490_D0.5230.43
356_Q372_A0.5230.43
743_D765_A0.5230.43
92_N150_V0.5230.43
656_T679_L0.5230.43
265_A268_P0.5230.43
259_H382_A0.5230.43
58_A118_F0.5220.43
398_T666_D0.5210.43
216_P558_L0.5200.43
345_E349_A0.5190.43
760_D787_A0.5190.43
323_F341_D0.5190.43
659_A673_V0.5180.43
216_P561_Q0.5180.43
34_D405_A0.5180.43
700_G703_A0.5180.43
621_F677_D0.5180.43
277_A302_E0.5180.43
664_F667_M0.5180.43
774_D791_A0.5180.43
599_L673_V0.5170.42
180_W487_T0.5170.42
385_Y393_A0.5170.42
58_A62_A0.5170.42
499_A509_D0.5170.42
559_T609_P0.5160.42
109_M112_Q0.5160.42
750_L759_R0.5160.42
163_C185_P0.5150.42
751_I754_T0.5150.42
213_D556_A0.5150.42
648_Y651_R0.5150.42
783_Y787_A0.5150.42
500_S505_D0.5140.42
217_S224_R0.5140.42
344_H368_V0.5140.42
162_S185_P0.5140.42
497_R503_F0.5130.42
567_E609_P0.5130.42
239_V248_V0.5130.42
530_V534_L0.5130.42
38_V60_T0.5130.42
521_E557_G0.5120.42
315_E318_V0.5120.42
97_N100_E0.5120.42
133_Y492_S0.5120.42
408_V766_G0.5120.42
135_K442_D0.5120.42
183_D576_K0.5110.42
31_D73_D0.5110.42
789_A793_D0.5100.42
328_V334_M0.5100.42
42_F536_S0.5100.42
469_T473_D0.5090.42
749_S785_V0.5090.42
586_V593_T0.5090.42
720_W725_G0.5080.41
62_A599_L0.5080.41
567_E576_K0.5080.41
429_I481_E0.5080.41
465_D468_Q0.5080.41
763_D781_W0.5070.41
266_L320_V0.5070.41
657_V679_L0.5070.41
573_S577_D0.5070.41
49_L139_W0.5060.41
55_R58_A0.5060.41
307_A333_L0.5050.41
171_Q489_L0.5040.41
351_D726_D0.5040.41
526_D530_V0.5030.41
558_L561_Q0.5030.41
371_A374_T0.5030.41
9_H615_V0.5020.41
122_W125_E0.5020.41
190_D409_Q0.5020.41
344_H357_V0.5020.41
117_G591_A0.5020.41
253_T331_G0.5020.41
647_E651_R0.5010.41
89_N179_C0.5000.40
622_L625_L0.5000.40
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2v0cA 1 0.8249 100 0.267 Contact Map
4arcA 1 0.8554 100 0.272 Contact Map
1gaxA 1 0.8678 100 0.439 Contact Map
3ziuA 1 0.6814 100 0.458 Contact Map
1ffyA 1 0.8927 100 0.48 Contact Map
1ileA 1 0.7966 100 0.482 Contact Map
1wz2A 1 0.8881 100 0.495 Contact Map
1wkbA 1 0.7186 100 0.54 Contact Map
4qreA 1 0.5424 100 0.701 Contact Map
1rqgA 2 0.5627 100 0.704 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0191 seconds.