THSA - HALSA - GREMLIN Contacts

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THSA - Thermosome subunit alpha

UniProt:	Q9HN70	Sequences: MAQQMGNQPLIVLSEDSQRTSGEDAQSMNITAGKAVAESVRTTLGPKGMDKMLVDSSGEVVVTNDGVTILKEMDIEHPAANMIVEVAETQETEVGDGTTTSVVVSGELLSEAETLLEQDIHATTLAQGYRQAAEKAKELLDDAAIDVSADDTETLEKIAATAMTGKGAENAKGVLSDLVVRAVQSVADDNDVDTDNVKVEKVTGGAIENSELIEGVIVDKERVSENMPYAVEDANIALVDDGLEVQETEIDTEVNVTDPDQLQNFLDQEEEQLKEMVDALKDAGANVVFADSGIDDMAQHYLAKEGILAVRRAKSDDFTRLSRATGATPVSNVNDIEAADLGAAGSVAQKDIGGDERIFVEDVEEAKSVTLILRGGTEHVVDEVERAIEDSLGVVRVTLEDGQVMPGGGAPETELAMQLRDFADSVGGREQLAVEAFADALEVIPRTLAENAGHDPIDSLVDLRSQHDGGDTEAGLDAYNGDVIDMESEGIVEPLRVKTQAIESATEAATMILRIDDVIAAGDLAGGQVGDDDGDDGPAGGPGGMGGGMGGMGGMGGMGGAM	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	562 (500)
Sequences:	5487 (2345)
Seq/√Len:	104.9

ECOLI - CH60
BACSU - CH60
HALSA - THSA THSB
SULSO - THSA THSB THSG

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
135_K	138_E	4.904	1.00
144_A	495_L	4.704	1.00
140_L	495_L	4.497	1.00
485_D	488_S	4.240	1.00
139_L	142_D	4.146	1.00
152_T	181_R	4.106	1.00
477_D	480_N	3.946	1.00
477_D	484_I	3.771	1.00
156_E	177_D	3.525	1.00
287_V	329_P	3.501	1.00
426_V	434_V	3.455	1.00
177_D	181_R	3.449	1.00
484_I	489_E	3.318	1.00
345_G	362_D	3.305	1.00
131_Q	430_E	3.228	1.00
473_E	485_D	3.188	1.00
111_E	439_D	3.186	1.00
445_P	463_L	3.065	1.00
412_E	498_K	2.985	1.00
476_L	481_G	2.971	1.00
64_N	69_I	2.957	1.00
152_T	184_Q	2.944	1.00
454_H	476_L	2.889	1.00
459_S	483_V	2.812	1.00
133_A	502_I	2.803	1.00
133_A	506_T	2.788	1.00
129_Y	506_T	2.738	1.00
108_L	129_Y	2.730	1.00
419_L	434_V	2.670	1.00
278_D	282_D	2.593	1.00
442_E	464_R	2.491	1.00
462_D	465_S	2.389	1.00
210_S	373_L	2.383	1.00
130_R	510_T	2.373	1.00
140_L	411_P	2.370	1.00
138_E	142_D	2.320	1.00
466_Q	474_A	2.311	1.00
420_R	438_A	2.305	1.00
294_I	309_A	2.280	1.00
139_L	418_Q	2.225	1.00
477_D	489_E	2.193	1.00
108_L	437_F	2.188	1.00
34_K	38_E	2.181	1.00
135_K	422_F	2.174	1.00
173_G	177_D	2.138	1.00
408_G	486_M	2.127	1.00
134_E	138_E	2.110	1.00
81_N	84_V	2.109	1.00
271_E	275_E	2.068	1.00
141_D	499_T	2.061	1.00
34_K	106_G	2.053	1.00
527_G	530_G	2.023	1.00
41_R	106_G	2.012	1.00
300_H	303_A	2.009	1.00
160_A	173_G	2.006	1.00
30_I	34_K	1.990	1.00
31_T	35_A	1.980	1.00
437_F	506_T	1.980	1.00
454_H	481_G	1.979	1.00
136_A	415_L	1.955	1.00
339_A	343_A	1.952	1.00
231_V	234_A	1.934	1.00
330_V	333_V	1.917	1.00
109_L	512_I	1.913	1.00
466_Q	471_D	1.885	1.00
124_T	430_E	1.863	1.00
145_I	487_E	1.855	1.00
422_F	434_V	1.851	1.00
418_Q	421_D	1.849	1.00
449_A	454_H	1.848	1.00
152_T	177_D	1.847	1.00
230_A	346_S	1.839	1.00
179_V	388_I	1.837	1.00
404_V	492_V	1.828	1.00
135_K	418_Q	1.821	1.00
154_T	157_K	1.811	1.00
61_V	386_R	1.791	1.00
139_L	143_A	1.780	1.00
484_I	491_I	1.776	1.00
100_T	501_A	1.766	1.00
312_R	320_R	1.762	1.00
129_Y	437_F	1.758	1.00
37_A	106_G	1.752	1.00
386_R	389_E	1.745	1.00
23_E	27_S	1.741	1.00
344_A	360_V	1.736	1.00
422_F	425_S	1.734	1.00
279_A	282_D	1.718	1.00
413_T	445_P	1.717	1.00
229_Y	287_V	1.702	1.00
19_R	517_D	1.682	1.00
137_K	141_D	1.678	1.00
183_V	399_L	1.667	1.00
28_M	31_T	1.661	1.00
462_D	482_D	1.657	1.00
115_L	432_L	1.651	1.00
107_E	110_S	1.632	1.00
126_A	130_R	1.631	1.00
91_E	386_R	1.621	1.00
238_L	311_R	1.620	1.00
64_N	386_R	1.603	1.00
136_A	441_L	1.600	1.00
416_A	464_R	1.590	1.00
414_E	472_T	1.579	1.00
442_E	446_R	1.577	1.00
59_E	379_H	1.570	1.00
462_D	466_Q	1.568	1.00
281_K	307_I	1.540	1.00
233_D	260_D	1.536	1.00
449_A	456_P	1.531	1.00
138_E	141_D	1.524	1.00
419_L	438_A	1.521	1.00
205_G	209_N	1.517	1.00
112_A	129_Y	1.491	1.00
132_A	437_F	1.487	1.00
321_L	360_V	1.474	1.00
115_L	120_I	1.458	1.00
411_P	415_L	1.454	1.00
353_G	356_E	1.448	1.00
443_V	447_T	1.444	1.00
34_K	110_S	1.428	1.00
111_E	114_T	1.425	1.00
38_E	106_G	1.424	1.00
441_L	502_I	1.405	1.00
135_K	434_V	1.402	1.00
237_A	336_I	1.401	1.00
413_T	464_R	1.401	1.00
137_K	503_E	1.395	1.00
135_K	139_L	1.391	1.00
274_K	278_D	1.391	1.00
486_M	491_I	1.390	1.00
136_A	419_L	1.377	1.00
231_V	263_Q	1.377	1.00
238_L	327_A	1.375	1.00
417_M	421_D	1.373	1.00
265_F	305_E	1.352	0.99
236_I	324_A	1.347	0.99
471_D	485_D	1.345	0.99
410_A	414_E	1.344	0.99
178_L	210_S	1.339	0.99
324_A	336_I	1.338	0.99
127_Q	430_E	1.331	0.99
400_E	496_R	1.328	0.99
91_E	393_G	1.325	0.99
289_F	360_V	1.315	0.99
64_N	164_T	1.299	0.99
474_A	483_V	1.295	0.99
339_A	342_G	1.280	0.99
231_V	287_V	1.278	0.99
148_S	154_T	1.276	0.99
431_Q	435_E	1.273	0.99
145_I	154_T	1.273	0.99
343_A	364_E	1.265	0.99
33_G	512_I	1.262	0.99
339_A	348_A	1.229	0.99
131_Q	135_K	1.222	0.99
235_N	323_R	1.220	0.99
143_A	146_D	1.216	0.99
110_S	443_V	1.204	0.99
107_E	443_V	1.201	0.99
30_I	109_L	1.198	0.99
445_P	449_A	1.197	0.99
422_F	426_V	1.195	0.99
132_A	434_V	1.194	0.99
435_E	439_D	1.193	0.99
254_V	257_T	1.185	0.99
203_T	373_L	1.179	0.99
461_V	465_S	1.177	0.99
401_D	496_R	1.158	0.98
153_E	156_E	1.154	0.98
406_P	487_E	1.153	0.98
158_I	404_V	1.150	0.98
120_I	432_L	1.150	0.98
406_P	410_A	1.149	0.98
471_D	474_A	1.148	0.98
244_E	269_E	1.142	0.98
28_M	77_H	1.136	0.98
63_T	383_E	1.133	0.98
414_E	473_E	1.132	0.98
310_V	358_I	1.131	0.98
91_E	389_E	1.123	0.98
201_K	382_D	1.120	0.98
140_L	499_T	1.119	0.98
238_L	313_A	1.114	0.98
373_L	381_V	1.112	0.98
33_G	83_I	1.111	0.98
18_Q	520_A	1.101	0.98
427_G	434_V	1.100	0.98
205_G	373_L	1.090	0.98
344_A	366_A	1.090	0.98
386_R	393_G	1.088	0.98
258_D	261_Q	1.083	0.98
86_V	101_S	1.079	0.97
428_G	431_Q	1.077	0.97
238_L	305_E	1.075	0.97
499_T	503_E	1.068	0.97
435_E	438_A	1.065	0.97
351_D	354_G	1.050	0.97
65_D	68_T	1.048	0.97
293_G	296_D	1.043	0.97
459_S	476_L	1.043	0.97
69_I	386_R	1.041	0.97
238_L	322_S	1.040	0.97
131_Q	426_V	1.036	0.97
235_N	284_G	1.029	0.97
288_V	302_L	1.029	0.97
142_D	418_Q	1.027	0.97
56_S	78_P	1.026	0.97
337_E	340_D	1.024	0.97
416_A	442_E	1.023	0.97
477_D	491_I	1.020	0.96
143_A	472_T	1.017	0.96
461_V	464_R	1.013	0.96
426_V	430_E	1.011	0.96
521_A	524_L	1.010	0.96
454_H	459_S	1.007	0.96
66_G	99_T	1.006	0.96
494_P	497_V	1.006	0.96
55_D	72_E	1.006	0.96
383_E	386_R	1.004	0.96
337_E	341_L	1.003	0.96
392_L	396_R	1.003	0.96
44_L	103_V	1.001	0.96
149_A	154_T	0.994	0.96
44_L	100_T	0.994	0.96
76_E	525_A	0.993	0.96
234_A	287_V	0.993	0.96
405_M	495_L	0.992	0.96
260_D	323_R	0.988	0.96
243_L	280_L	0.985	0.96
87_A	102_V	0.984	0.96
76_E	522_G	0.983	0.96
427_G	430_E	0.981	0.96
415_L	441_L	0.980	0.96
448_L	478_A	0.980	0.96
230_A	326_G	0.978	0.95
234_A	324_A	0.978	0.95
65_D	390_D	0.976	0.95
388_I	392_L	0.972	0.95
99_T	390_D	0.968	0.95
350_K	356_E	0.966	0.95
523_D	527_G	0.966	0.95
423_A	431_Q	0.962	0.95
38_E	41_R	0.959	0.95
98_T	390_D	0.958	0.95
149_A	153_E	0.955	0.95
232_E	326_G	0.954	0.95
155_L	184_Q	0.953	0.95
156_E	159_A	0.950	0.95
289_F	313_A	0.950	0.95
20_T	28_M	0.944	0.95
140_L	415_L	0.942	0.94
185_S	214_E	0.939	0.94
30_I	113_E	0.937	0.94
347_V	363_V	0.936	0.94
371_L	388_I	0.933	0.94
27_S	31_T	0.933	0.94
143_A	415_L	0.931	0.94
41_R	447_T	0.931	0.94
267_D	271_E	0.928	0.94
156_E	160_A	0.928	0.94
487_E	492_V	0.927	0.94
111_E	440_A	0.927	0.94
33_G	109_L	0.925	0.94
137_K	499_T	0.918	0.94
261_Q	264_N	0.918	0.94
156_E	173_G	0.911	0.93
343_A	348_A	0.910	0.93
417_M	420_R	0.909	0.93
37_A	41_R	0.909	0.93
139_L	415_L	0.908	0.93
230_A	348_A	0.907	0.93
279_A	285_A	0.905	0.93
264_N	267_D	0.904	0.93
181_R	214_E	0.903	0.93
425_S	434_V	0.901	0.93
181_R	185_S	0.901	0.93
20_T	24_D	0.900	0.93
308_L	347_V	0.899	0.93
437_F	441_L	0.897	0.93
178_L	371_L	0.896	0.93
463_L	483_V	0.895	0.93
358_I	361_E	0.895	0.93
238_L	265_F	0.894	0.93
157_K	490_G	0.893	0.93
340_D	344_A	0.893	0.93
383_E	387_A	0.892	0.93
128_G	433_A	0.889	0.93
495_L	499_T	0.888	0.93
234_A	286_N	0.888	0.93
302_L	309_A	0.886	0.92
398_T	402_G	0.886	0.92
159_A	395_V	0.885	0.92
411_P	495_L	0.885	0.92
53_L	519_I	0.884	0.92
373_L	384_V	0.884	0.92
279_A	334_N	0.882	0.92
450_E	456_P	0.881	0.92
183_V	197_V	0.880	0.92
349_Q	356_E	0.880	0.92
212_L	289_F	0.867	0.92
482_D	489_E	0.865	0.92
454_H	478_A	0.863	0.91
155_L	159_A	0.861	0.91
165_G	172_K	0.861	0.91
512_I	518_V	0.859	0.91
18_Q	522_G	0.857	0.91
41_R	450_E	0.856	0.91
108_L	512_I	0.856	0.91
414_E	474_A	0.855	0.91
42_T	51_K	0.852	0.91
416_A	441_L	0.852	0.91
413_T	442_E	0.851	0.91
280_L	285_A	0.847	0.91
158_I	394_V	0.847	0.91
201_K	385_E	0.846	0.91
152_T	156_E	0.845	0.91
63_T	69_I	0.845	0.91
63_T	386_R	0.845	0.91
124_T	479_Y	0.845	0.91
473_E	487_E	0.842	0.90
389_E	393_G	0.841	0.90
141_D	144_A	0.840	0.90
414_E	463_L	0.839	0.90
423_A	438_A	0.839	0.90
183_V	392_L	0.837	0.90
415_L	418_Q	0.836	0.90
207_I	384_V	0.835	0.90
281_K	305_E	0.834	0.90
18_Q	521_A	0.834	0.90
141_D	495_L	0.833	0.90
406_P	473_E	0.833	0.90
124_T	427_G	0.833	0.90
413_T	416_A	0.832	0.90
139_L	414_E	0.830	0.90
500_Q	503_E	0.829	0.90
128_G	132_A	0.828	0.90
130_R	134_E	0.828	0.90
30_I	110_S	0.827	0.90
339_A	350_K	0.825	0.90
425_S	431_Q	0.824	0.89
133_A	437_F	0.824	0.89
423_A	435_E	0.821	0.89
429_R	432_L	0.819	0.89
71_K	88_E	0.819	0.89
120_I	429_R	0.815	0.89
443_V	446_R	0.814	0.89
143_A	411_P	0.813	0.89
227_M	293_G	0.810	0.89
135_K	142_D	0.809	0.89
476_L	482_D	0.809	0.89
526_G	529_V	0.803	0.88
83_I	86_V	0.803	0.88
449_A	476_L	0.801	0.88
44_L	444_I	0.798	0.88
324_A	363_V	0.796	0.88
100_T	444_I	0.796	0.88
343_A	350_K	0.795	0.88
263_Q	267_D	0.794	0.88
133_A	137_K	0.792	0.88
236_I	344_A	0.791	0.87
401_D	499_T	0.788	0.87
522_G	526_G	0.787	0.87
414_E	417_M	0.787	0.87
241_D	316_D	0.786	0.87
158_I	398_T	0.786	0.87
153_E	157_K	0.785	0.87
484_I	488_S	0.780	0.87
143_A	406_P	0.780	0.87
38_E	42_T	0.776	0.86
239_V	243_L	0.775	0.86
182_A	204_G	0.774	0.86
263_Q	329_P	0.771	0.86
419_L	422_F	0.771	0.86
214_E	361_E	0.771	0.86
110_S	503_E	0.770	0.86
445_P	460_L	0.770	0.86
314_K	320_R	0.770	0.86
50_D	64_N	0.769	0.86
231_V	286_N	0.767	0.86
224_S	227_M	0.767	0.86
149_A	188_D	0.766	0.86
136_A	418_Q	0.765	0.86
420_R	435_E	0.765	0.86
55_D	59_E	0.763	0.86
45_G	48_G	0.762	0.85
277_V	305_E	0.759	0.85
81_N	396_R	0.758	0.85
32_A	79_A	0.758	0.85
240_D	317_D	0.758	0.85
350_K	361_E	0.756	0.85
217_I	268_Q	0.755	0.85
297_M	355_D	0.755	0.85
345_G	348_A	0.754	0.85
36_V	83_I	0.752	0.85
339_A	354_G	0.752	0.85
327_A	336_I	0.751	0.85
105_S	505_A	0.750	0.85
87_A	101_S	0.747	0.84
315_S	318_F	0.746	0.84
348_A	361_E	0.744	0.84
185_S	369_V	0.743	0.84
477_D	482_D	0.743	0.84
436_A	439_D	0.741	0.84
439_D	442_E	0.741	0.84
66_G	95_G	0.740	0.84
66_G	390_D	0.739	0.84
143_A	418_Q	0.739	0.84
55_D	61_V	0.739	0.84
343_A	354_G	0.739	0.84
348_A	352_I	0.729	0.83
277_V	301_Y	0.725	0.83
90_Q	504_S	0.723	0.82
421_D	425_S	0.723	0.82
131_Q	434_V	0.722	0.82
522_G	527_G	0.722	0.82
442_E	455_D	0.721	0.82
164_T	386_R	0.720	0.82
420_R	439_D	0.720	0.82
431_Q	434_V	0.719	0.82
214_E	362_D	0.718	0.82
417_M	464_R	0.718	0.82
70_L	102_V	0.717	0.82
347_V	360_V	0.716	0.82
146_D	149_A	0.714	0.82
449_A	459_S	0.714	0.82
497_V	501_A	0.712	0.81
525_A	529_V	0.712	0.81
159_A	180_V	0.712	0.81
124_T	127_Q	0.711	0.81
475_G	486_M	0.709	0.81
165_G	498_K	0.708	0.81
116_L	125_L	0.708	0.81
343_A	352_I	0.705	0.81
524_L	527_G	0.703	0.81
275_E	278_D	0.700	0.80
463_L	466_Q	0.699	0.80
525_A	528_Q	0.698	0.80
164_T	383_E	0.694	0.80
63_T	84_V	0.693	0.80
216_V	227_M	0.693	0.80
197_V	381_V	0.691	0.79
259_P	285_A	0.691	0.79
139_L	419_L	0.690	0.79
420_R	442_E	0.689	0.79
131_Q	422_F	0.686	0.79
297_M	301_Y	0.686	0.79
273_L	297_M	0.686	0.79
428_G	432_L	0.685	0.79
232_E	346_S	0.685	0.79
29_N	109_L	0.684	0.79
183_V	192_V	0.683	0.79
160_A	176_S	0.683	0.79
222_R	308_L	0.683	0.79
405_M	411_P	0.681	0.78
183_V	395_V	0.679	0.78
29_N	518_V	0.679	0.78
241_D	311_R	0.677	0.78
229_Y	329_P	0.677	0.78
264_N	286_N	0.675	0.78
305_E	336_I	0.675	0.78
237_A	341_L	0.674	0.78
285_A	341_L	0.674	0.78
413_T	460_L	0.671	0.77
344_A	348_A	0.669	0.77
246_Q	275_E	0.669	0.77
245_V	248_T	0.667	0.77
439_D	443_V	0.666	0.77
129_Y	132_A	0.665	0.77
406_P	486_M	0.664	0.77
405_M	492_V	0.664	0.77
357_R	360_V	0.661	0.76
189_D	344_A	0.661	0.76
129_Y	133_A	0.661	0.76
275_E	279_A	0.658	0.76
423_A	426_V	0.657	0.76
322_S	329_P	0.657	0.76
278_D	305_E	0.656	0.76
30_I	120_I	0.654	0.76
240_D	315_S	0.654	0.76
65_D	375_G	0.654	0.76
91_E	390_D	0.652	0.75
41_R	443_V	0.649	0.75
493_E	498_K	0.648	0.75
449_A	460_L	0.647	0.75
526_G	530_G	0.647	0.75
136_A	139_L	0.646	0.75
155_L	395_V	0.646	0.75
345_G	363_V	0.645	0.75
24_D	27_S	0.643	0.74
233_D	345_G	0.643	0.74
104_V	289_F	0.642	0.74
295_D	298_A	0.641	0.74
238_L	321_L	0.641	0.74
136_A	502_I	0.640	0.74
293_G	301_Y	0.639	0.74
61_V	72_E	0.639	0.74
234_A	347_V	0.638	0.74
104_V	505_A	0.636	0.74
291_D	302_L	0.636	0.74
462_D	483_V	0.635	0.73
339_A	344_A	0.635	0.73
381_V	384_V	0.634	0.73
363_V	366_A	0.634	0.73
179_V	391_S	0.633	0.73
237_A	327_A	0.632	0.73
312_R	317_D	0.631	0.73
222_R	349_Q	0.629	0.73
414_E	418_Q	0.628	0.73
63_T	164_T	0.628	0.73
222_R	227_M	0.628	0.73
462_D	474_A	0.628	0.73
68_T	386_R	0.628	0.73
56_S	524_L	0.628	0.73
522_G	528_Q	0.626	0.72
501_A	505_A	0.625	0.72
302_L	307_I	0.624	0.72
235_N	260_D	0.623	0.72
341_L	345_G	0.622	0.72
40_V	99_T	0.622	0.72
182_A	186_V	0.621	0.72
23_E	238_L	0.621	0.72
222_R	226_N	0.621	0.72
480_N	484_I	0.619	0.72
240_D	313_A	0.619	0.72
68_T	390_D	0.619	0.72
58_G	307_I	0.617	0.71
165_G	387_A	0.617	0.71
341_L	344_A	0.616	0.71
243_L	298_A	0.614	0.71
485_D	489_E	0.613	0.71
347_V	353_G	0.613	0.71
272_Q	276_M	0.612	0.71
343_A	363_V	0.611	0.71
378_E	382_D	0.611	0.71
136_A	438_A	0.611	0.71
87_A	105_S	0.609	0.70
423_A	434_V	0.609	0.70
342_G	349_Q	0.608	0.70
37_A	40_V	0.608	0.70
268_Q	272_Q	0.608	0.70
106_G	110_S	0.606	0.70
179_V	395_V	0.606	0.70
204_G	374_R	0.606	0.70
235_N	343_A	0.605	0.70
66_G	98_T	0.603	0.70
165_G	247_E	0.603	0.70
370_T	374_R	0.603	0.70
419_L	423_A	0.603	0.70
135_K	415_L	0.602	0.69
178_L	204_G	0.602	0.69
34_K	37_A	0.601	0.69
458_D	462_D	0.601	0.69
81_N	85_E	0.599	0.69
52_M	512_I	0.597	0.69
165_G	202_V	0.597	0.69
237_A	283_A	0.597	0.69
165_G	504_S	0.596	0.69
519_I	522_G	0.596	0.69
54_V	521_A	0.595	0.69
194_T	270_E	0.592	0.68
125_L	437_F	0.592	0.68
416_A	438_A	0.592	0.68
32_A	77_H	0.592	0.68
394_V	398_T	0.591	0.68
34_K	113_E	0.591	0.68
292_S	314_K	0.589	0.68
29_N	512_I	0.588	0.68
172_K	493_E	0.588	0.68
452_A	478_A	0.587	0.68
115_L	436_A	0.587	0.68
129_Y	433_A	0.586	0.67
500_Q	504_S	0.585	0.67
211_E	333_V	0.583	0.67
116_L	479_Y	0.583	0.67
474_A	484_I	0.582	0.67
141_D	401_D	0.582	0.67
232_E	362_D	0.582	0.67
524_L	528_Q	0.581	0.67
133_A	503_E	0.581	0.67
253_E	378_E	0.581	0.67
72_E	227_M	0.581	0.67
202_V	355_D	0.580	0.67
147_V	174_V	0.579	0.66
161_T	493_E	0.579	0.66
158_I	402_G	0.578	0.66
107_E	447_T	0.578	0.66
26_Q	516_D	0.577	0.66
82_M	508_A	0.577	0.66
210_S	308_L	0.577	0.66
159_A	162_A	0.576	0.66
132_A	153_E	0.576	0.66
466_Q	483_V	0.576	0.66
71_K	241_D	0.574	0.66
188_D	367_K	0.574	0.66
263_Q	269_E	0.574	0.66
238_L	289_F	0.572	0.66
346_S	361_E	0.571	0.65
197_V	246_Q	0.571	0.65
239_V	290_A	0.570	0.65
173_G	479_Y	0.570	0.65
406_P	472_T	0.570	0.65
350_K	359_F	0.569	0.65
121_H	514_R	0.569	0.65
240_D	318_F	0.569	0.65
442_E	460_L	0.569	0.65
348_A	354_G	0.568	0.65
29_N	52_M	0.568	0.65
142_D	145_I	0.568	0.65
388_I	394_V	0.568	0.65
340_D	343_A	0.566	0.65
234_A	327_A	0.565	0.65
93_E	500_Q	0.565	0.65
39_S	43_T	0.564	0.64
222_R	231_V	0.563	0.64
159_A	176_S	0.563	0.64
342_G	350_K	0.561	0.64
287_V	360_V	0.561	0.64
339_A	352_I	0.561	0.64
18_Q	27_S	0.560	0.64
100_T	104_V	0.560	0.64
18_Q	518_V	0.560	0.64
148_S	481_G	0.559	0.64
213_I	217_I	0.558	0.64
198_K	202_V	0.557	0.64
521_A	527_G	0.556	0.63
522_G	525_A	0.556	0.63
27_S	30_I	0.555	0.63
123_T	126_A	0.554	0.63
199_V	373_L	0.553	0.63
442_E	457_I	0.553	0.63
447_T	450_E	0.553	0.63
343_A	351_D	0.553	0.63
39_S	67_V	0.552	0.63
442_E	481_G	0.551	0.63
181_R	184_Q	0.551	0.63
54_V	257_T	0.550	0.63
272_Q	275_E	0.549	0.62
115_L	513_L	0.549	0.62
443_V	450_E	0.549	0.62
228_P	303_A	0.548	0.62
342_G	346_S	0.548	0.62
269_E	441_L	0.548	0.62
182_A	212_L	0.548	0.62
266_L	298_A	0.547	0.62
120_I	428_G	0.547	0.62
338_A	345_G	0.545	0.62
164_T	393_G	0.544	0.62
237_A	285_A	0.543	0.62
185_S	208_E	0.543	0.62
417_M	474_A	0.543	0.62
297_M	300_H	0.543	0.62
112_A	128_G	0.542	0.61
311_R	314_K	0.542	0.61
455_D	460_L	0.542	0.61
114_T	118_Q	0.542	0.61
108_L	506_T	0.542	0.61
55_D	58_G	0.542	0.61
300_H	304_K	0.542	0.61
183_V	369_V	0.541	0.61
236_I	327_A	0.541	0.61
410_A	463_L	0.540	0.61
44_L	99_T	0.540	0.61
344_A	347_V	0.540	0.61
407_G	491_I	0.539	0.61
95_G	390_D	0.539	0.61
108_L	133_A	0.538	0.61
207_I	392_L	0.538	0.61
386_R	415_L	0.538	0.61
50_D	514_R	0.538	0.61
233_D	343_A	0.537	0.61
351_D	356_E	0.537	0.61
163_M	175_L	0.537	0.61
283_A	336_I	0.535	0.60
236_I	325_T	0.534	0.60
303_A	317_D	0.533	0.60
300_H	307_I	0.533	0.60
97_G	497_V	0.532	0.60
104_V	502_I	0.531	0.60
240_D	312_R	0.531	0.60
61_V	389_E	0.530	0.60
350_K	354_G	0.529	0.60
222_R	358_I	0.529	0.60
197_V	341_L	0.529	0.60
87_A	91_E	0.528	0.59
292_S	312_R	0.528	0.59
464_R	474_A	0.526	0.59
40_V	43_T	0.526	0.59
44_L	47_K	0.524	0.59
211_E	361_E	0.522	0.59
20_T	54_V	0.522	0.59
411_P	493_E	0.521	0.58
445_P	461_V	0.521	0.58
89_T	93_E	0.521	0.58
78_P	194_T	0.520	0.58
466_Q	472_T	0.519	0.58
18_Q	23_E	0.519	0.58
255_N	259_P	0.519	0.58
83_I	512_I	0.519	0.58
235_N	255_N	0.518	0.58
292_S	295_D	0.518	0.58
342_G	348_A	0.518	0.58
231_V	327_A	0.517	0.58
109_L	434_V	0.517	0.58
523_D	526_G	0.517	0.58
511_M	515_I	0.517	0.58
100_T	497_V	0.516	0.58
19_R	22_G	0.515	0.58
277_V	298_A	0.515	0.58
158_I	260_D	0.515	0.58
211_E	372_I	0.515	0.58
271_E	274_K	0.514	0.57
95_G	98_T	0.514	0.57
406_P	474_A	0.513	0.57
251_D	255_N	0.513	0.57
439_D	457_I	0.513	0.57
131_Q	364_E	0.512	0.57
127_Q	510_T	0.512	0.57
391_S	399_L	0.511	0.57
104_V	108_L	0.511	0.57
134_E	421_D	0.511	0.57
106_G	109_L	0.511	0.57
396_R	491_I	0.510	0.57
254_V	258_D	0.510	0.57
352_I	357_R	0.509	0.57
345_G	349_Q	0.509	0.57
83_I	105_S	0.509	0.57
260_D	264_N	0.509	0.57
91_E	98_T	0.509	0.57
108_L	436_A	0.508	0.57
239_V	285_A	0.508	0.57
61_V	393_G	0.508	0.57
458_D	463_L	0.507	0.56
351_D	355_D	0.507	0.56
432_L	438_A	0.505	0.56
152_T	519_I	0.505	0.56
109_L	287_V	0.504	0.56
157_K	337_E	0.503	0.56
122_A	302_L	0.503	0.56
126_A	511_M	0.503	0.56
186_V	192_V	0.503	0.56
401_D	495_L	0.503	0.56
92_T	361_E	0.503	0.56
416_A	443_V	0.503	0.56
65_D	98_T	0.502	0.56
202_V	512_I	0.502	0.56
53_L	72_E	0.501	0.56
115_L	428_G	0.501	0.56
20_T	522_G	0.501	0.56
67_V	71_K	0.500	0.55

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1q3qA	4	0.9146	100	0.094	Contact Map
3ruvA	6	0.9146	100	0.101	Contact Map
3j1bA	4	0.8986	100	0.104	Contact Map
1a6dA	2	0.8879	100	0.114	Contact Map
3p9dG	1	0.9004	100	0.122	Contact Map
3ko1A	5	0.8897	100	0.124	Contact Map
1a6dB	2	0.8861	100	0.13	Contact Map
3p9dA	1	0.9288	100	0.141	Contact Map
3p9dD	2	0.9093	100	0.154	Contact Map
3p9dE	1	0.9093	100	0.156	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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