GREMLIN Database
Q9HN35 - DNA-binding protein MutS2
UniProt: Q9HN35 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 669 (532)
Sequences: 4485 (2966)
Seq/√Len: 128.6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
451_G508_E5.2101.00
449_I452_G4.6171.00
211_E214_A4.5561.00
432_A503_L4.4441.00
215_E439_L4.1471.00
218_P439_L3.5421.00
325_S356_A3.4241.00
441_E511_R3.3981.00
448_R511_R3.3871.00
298_R393_R3.2541.00
183_G498_L3.2461.00
450_E509_A3.1661.00
207_P211_E3.0411.00
516_A557_A2.9601.00
218_P222_L2.9581.00
496_V515_I2.8871.00
271_E276_T2.7581.00
279_V283_D2.7361.00
180_L184_Y2.7231.00
217_V428_V2.6861.00
280_N283_D2.6751.00
296_R302_G2.6541.00
303_E385_S2.6541.00
283_D287_S2.6421.00
428_V503_L2.5511.00
207_P442_R2.5231.00
442_R512_V2.5011.00
450_E508_E2.4531.00
284_A287_S2.4431.00
469_Y492_V2.3981.00
443_G511_R2.3791.00
450_E468_E2.3731.00
350_L374_R2.3681.00
214_A442_R2.2911.00
497_V518_L2.2881.00
166_L199_V2.2691.00
185_T434_D2.2621.00
280_N284_A2.2531.00
161_A166_L2.2101.00
448_R470_G2.1601.00
223_S226_A2.1571.00
495_V505_V2.1541.00
473_G613_T2.1491.00
320_G378_A2.0981.00
166_L501_M2.0341.00
474_V584_L2.0321.00
167_S200_E2.0181.00
306_V310_G2.0171.00
221_V433_A1.9681.00
452_G495_V1.9331.00
475_A617_I1.9281.00
362_R365_G1.9251.00
611_G614_V1.9111.00
156_Y160_A1.8921.00
155_T517_E1.8921.00
211_E439_L1.8821.00
209_A212_R1.8801.00
451_G468_E1.8751.00
229_R426_L1.8741.00
408_L411_P1.8621.00
588_H611_G1.8591.00
282_L287_S1.8531.00
345_A353_R1.8471.00
430_R434_D1.8441.00
198_E425_A1.8431.00
347_E350_L1.8431.00
198_E424_V1.8321.00
214_A218_P1.8311.00
301_I390_R1.8191.00
316_L320_G1.7961.00
477_L595_V1.7871.00
453_R458_D1.7861.00
207_P514_A1.7821.00
218_P504_P1.7701.00
186_T192_E1.7621.00
279_V282_L1.7521.00
299_E303_E1.7411.00
236_V256_A1.7371.00
283_D288_D1.7351.00
282_L286_V1.7321.00
404_T407_D1.7321.00
152_D206_E1.7301.00
562_V587_L1.7171.00
549_D555_E1.7131.00
553_G656_A1.6981.00
441_E509_A1.6891.00
476_L614_V1.6881.00
377_D381_R1.6841.00
279_V285_A1.6831.00
278_A283_D1.6821.00
558_A591_G1.6761.00
448_R509_A1.6671.00
187_V229_R1.6671.00
187_V233_R1.6531.00
273_D276_T1.6421.00
585_E659_E1.6361.00
437_C498_L1.6271.00
154_E204_R1.6261.00
203_V209_A1.6181.00
276_T279_V1.6131.00
654_D658_G1.6121.00
562_V592_A1.6121.00
659_E662_Y1.6061.00
396_G400_E1.6041.00
280_N285_A1.5971.00
251_D254_D1.5941.00
295_D306_V1.5911.00
437_C455_P1.5861.00
452_G491_L1.5831.00
312_D316_L1.5811.00
206_E209_A1.5761.00
321_A325_S1.5731.00
428_V501_M1.5711.00
228_N263_D1.5681.00
564_V567_L1.5671.00
169_E174_A1.5661.00
547_V583_I1.5651.00
334_E342_A1.5651.00
400_E404_T1.5501.00
210_M442_R1.5341.00
620_A634_V1.5301.00
295_D305_D1.5221.00
194_F424_V1.5201.00
496_V561_L1.5201.00
284_A288_D1.5191.00
169_E178_A1.5161.00
300_A303_E1.5161.00
319_R324_D1.5141.00
229_R430_R1.5061.00
450_E470_G1.5051.00
194_F420_L1.4881.00
271_E279_V1.4821.00
234_A259_H1.4691.00
285_A288_D1.4671.00
275_L284_A1.4631.00
588_H613_T1.4471.00
451_G632_S1.4471.00
281_D285_A1.4411.00
275_L282_L1.4361.00
274_R278_A1.4331.00
349_Q352_L1.4271.00
280_N287_S1.4271.00
214_A439_L1.4261.00
547_V564_V1.4241.00
276_T280_N1.4211.00
359_L362_R1.4181.00
493_A563_L1.4141.00
199_V501_M1.4081.00
346_L349_Q1.4021.00
282_L288_D1.4011.00
282_L285_A1.3961.00
626_E648_E1.3871.00
488_T633_P1.3831.00
278_A284_A1.3801.00
275_L283_D1.3631.00
279_V284_A1.3501.00
330_E348_E1.3491.00
283_D286_V1.3391.00
215_E218_P1.3361.00
344_D371_P1.3331.00
586_A590_A1.3331.00
220_R228_N1.3241.00
648_E654_D1.3231.00
185_T431_F1.3191.00
121_P147_C1.3151.00
216_V425_A1.3111.00
431_F435_F1.3081.00
472_D615_D1.3061.00
293_A397_R1.2971.00
447_F496_V1.2951.00
204_R514_A1.2901.00
183_G431_F1.2861.00
617_I635_K1.2841.00
203_V210_M1.2841.00
615_D635_K1.2831.00
469_Y488_T1.2771.00
280_N288_D1.2761.00
472_D635_K1.2711.00
122_R126_L1.2651.00
153_A201_G1.2641.00
183_G501_M1.2641.00
618_H634_V1.2621.00
271_E275_L1.2581.00
361_R365_G1.2581.00
579_I583_I1.2531.00
547_V567_L1.2461.00
645_L661_F1.2421.00
587_L594_G1.2411.00
588_H614_V1.2391.00
190_L420_L1.2391.00
279_V287_S1.2381.00
606_D609_G1.2381.00
449_I495_V1.2331.00
228_N426_L1.2301.00
474_V588_H1.2301.00
211_E215_E1.2281.00
403_A407_D1.1970.99
275_L278_A1.1940.99
393_R396_G1.1940.99
500_H515_I1.1910.99
210_M214_A1.1900.99
207_P214_A1.1820.99
169_E177_L1.1790.99
247_D292_V1.1780.99
375_D380_A1.1760.99
231_R259_H1.1740.99
214_A217_V1.1740.99
320_G325_S1.1600.99
278_A288_D1.1590.99
619_A633_P1.1470.99
273_D277_R1.1400.99
452_G469_Y1.1360.99
278_A281_D1.1260.99
161_A200_E1.1260.99
278_A286_V1.1240.99
314_L317_V1.1200.99
250_L405_L1.1190.99
276_T283_D1.1180.99
272_L276_T1.1160.99
281_D288_D1.1140.99
276_T282_L1.1130.99
520_Y527_T1.1070.99
357_A362_R1.1050.99
449_I469_Y1.1010.99
271_E274_R1.1010.99
343_R357_A1.1000.99
235_A256_A1.0990.99
177_L181_A1.0980.99
315_S318_E1.0980.99
443_G446_G1.0970.99
271_E284_A1.0920.99
328_G345_A1.0910.99
231_R263_D1.0880.99
648_E661_F1.0860.99
278_A287_S1.0860.99
161_A167_S1.0830.99
318_E322_G1.0800.99
500_H514_A1.0800.99
442_R513_P1.0740.99
275_L280_N1.0720.99
625_G661_F1.0710.99
381_R385_S1.0710.99
469_Y491_L1.0700.99
585_E589_E1.0700.99
298_R400_E1.0660.99
245_D406_A1.0600.99
311_A387_T1.0540.99
451_G466_P1.0540.99
330_E349_Q1.0490.98
194_F198_E1.0480.98
398_K402_A1.0470.98
214_A501_M1.0460.98
436_D508_E1.0440.98
270_D274_R1.0400.98
361_R364_F1.0360.98
277_R283_D1.0320.98
537_L545_E1.0230.98
220_R426_L1.0210.98
295_D309_E1.0160.98
513_P593_S1.0120.98
152_D209_A1.0090.98
271_E282_L1.0070.98
273_D279_V1.0050.98
277_R282_L1.0030.98
265_S268_G1.0020.98
532_A537_L1.0010.98
160_A520_Y1.0010.98
278_A282_L1.0000.98
247_D395_A0.9940.98
608_C614_V0.9920.98
280_N286_V0.9900.98
608_C635_K0.9880.98
279_V286_V0.9870.98
439_L504_P0.9860.98
167_S180_L0.9850.98
214_A428_V0.9850.98
307_T385_S0.9840.98
395_A399_R0.9830.98
275_L279_V0.9800.98
495_V506_P0.9780.98
404_T408_L0.9770.98
168_V173_D0.9760.98
313_L317_V0.9740.98
354_G359_L0.9730.97
548_A554_E0.9700.97
303_E307_T0.9670.97
313_L382_V0.9670.97
495_V510_A0.9660.97
557_A560_R0.9560.97
198_E203_V0.9550.97
178_A181_A0.9540.97
359_L365_G0.9530.97
214_A504_P0.9510.97
207_P444_G0.9480.97
217_V221_V0.9480.97
193_A237_S0.9450.97
468_E632_S0.9410.97
281_D294_N0.9410.97
279_V288_D0.9390.97
123_D127_E0.9360.97
211_E441_E0.9350.97
425_A428_V0.9340.97
357_A361_R0.9310.97
359_L363_V0.9280.97
623_E640_R0.9270.97
346_L350_L0.9200.96
271_E280_N0.9200.96
198_E421_E0.9170.96
471_V475_A0.9160.96
163_F170_I0.9160.96
336_D342_A0.9140.96
617_I633_P0.9140.96
447_F492_V0.9120.96
231_R262_G0.9100.96
365_G371_P0.9100.96
321_A357_A0.9060.96
301_I397_R0.9050.96
360_A363_V0.9050.96
242_A412_T0.9020.96
300_A389_A0.9020.96
277_R280_N0.9000.96
255_G258_A0.8990.96
605_R637_H0.8980.96
475_A488_T0.8950.96
270_D282_L0.8950.96
648_E657_V0.8950.96
618_H637_H0.8940.96
274_R283_D0.8930.96
427_A431_F0.8930.96
262_G265_S0.8900.96
307_T317_V0.8870.96
444_G559_S0.8870.96
532_A535_A0.8810.96
505_V510_A0.8810.96
330_E346_L0.8800.95
424_V428_V0.8780.95
500_H512_V0.8750.95
578_K581_A0.8740.95
496_V512_V0.8740.95
438_V504_P0.8670.95
263_D419_A0.8670.95
360_A365_G0.8600.95
242_A409_R0.8590.95
359_L372_V0.8580.95
437_C458_D0.8580.95
574_G600_L0.8560.95
477_L633_P0.8540.95
157_S517_E0.8530.95
359_L364_F0.8490.95
489_L597_V0.8490.95
293_A401_L0.8480.94
221_V504_P0.8470.94
467_V491_L0.8470.94
275_L286_V0.8460.94
382_V385_S0.8450.94
169_E172_E0.8410.94
153_A203_V0.8400.94
360_A364_F0.8360.94
317_V320_G0.8350.94
281_D284_A0.8320.94
275_L285_A0.8280.94
292_V395_A0.8280.94
539_D570_I0.8230.94
378_A381_R0.8220.94
204_R559_S0.8210.93
464_T487_S0.8200.93
183_G427_A0.8160.93
211_E442_R0.8150.93
272_L284_A0.8140.93
175_R180_L0.8140.93
281_D286_V0.8130.93
154_E518_L0.8130.93
446_G559_S0.8130.93
270_D276_T0.8110.93
148_V153_A0.8080.93
445_R511_R0.8050.93
186_T427_A0.8040.93
210_M514_A0.8020.93
489_L492_V0.8000.93
519_H555_E0.8000.93
249_D252_A0.7970.92
305_D390_R0.7970.92
185_T427_A0.7970.92
251_D255_G0.7950.92
442_R499_A0.7930.92
492_V561_L0.7930.92
217_V429_A0.7920.92
184_Y192_E0.7870.92
276_T288_D0.7830.92
452_G492_V0.7820.92
621_G627_L0.7810.92
652_E656_A0.7810.92
358_K362_R0.7780.92
271_E278_A0.7780.92
214_A221_V0.7780.92
314_L318_E0.7770.91
210_M501_M0.7750.91
214_A498_L0.7750.91
357_A365_G0.7740.91
445_R593_S0.7740.91
442_R514_A0.7740.91
259_H262_G0.7730.91
483_G618_H0.7710.91
417_H421_E0.7700.91
556_S592_A0.7670.91
475_A615_D0.7640.91
221_V429_A0.7630.91
446_G593_S0.7630.91
513_P559_S0.7620.91
433_A436_D0.7620.91
620_A632_S0.7620.91
227_A266_V0.7590.91
618_H621_G0.7580.90
431_F437_C0.7580.90
326_L329_R0.7570.90
271_E285_A0.7560.90
273_D278_A0.7560.90
217_V504_P0.7560.90
277_R284_A0.7560.90
446_G513_P0.7540.90
154_E497_V0.7520.90
203_V500_H0.7500.90
587_L592_A0.7500.90
569_S572_E0.7480.90
238_V412_T0.7470.90
303_E306_V0.7460.90
482_S487_S0.7460.90
235_A419_A0.7430.90
581_A585_E0.7430.90
274_R277_R0.7430.90
276_T285_A0.7420.89
260_L415_L0.7390.89
618_H636_D0.7390.89
154_E501_M0.7390.89
260_L419_A0.7380.89
658_G662_Y0.7370.89
515_I593_S0.7370.89
219_E223_S0.7340.89
277_R286_V0.7340.89
658_G661_F0.7320.89
197_V201_G0.7310.89
204_R500_H0.7310.89
156_Y161_A0.7300.89
627_L645_L0.7290.89
241_A253_L0.7290.89
274_R281_D0.7270.89
249_D257_L0.7270.89
447_F513_P0.7260.88
120_T123_D0.7230.88
149_A152_D0.7220.88
577_A581_A0.7190.88
400_E403_A0.7170.88
410_A413_E0.7160.88
194_F197_V0.7150.88
160_A549_D0.7140.88
314_L320_G0.7140.88
350_L353_R0.7110.87
473_G591_G0.7090.87
121_P124_D0.7090.87
231_R266_V0.7070.87
405_L412_T0.7070.87
300_A396_G0.7060.87
458_D495_V0.7060.87
657_V661_F0.7050.87
447_F512_V0.7030.87
256_A419_A0.7020.87
166_L497_V0.7020.87
173_D176_D0.7010.87
424_V427_A0.7000.87
273_D280_N0.7000.87
357_A360_A0.6960.86
167_S199_V0.6960.86
357_A363_V0.6960.86
174_A388_A0.6960.86
578_K582_G0.6960.86
292_V305_D0.6950.86
208_D211_E0.6940.86
446_G558_A0.6940.86
221_V432_A0.6930.86
331_L340_G0.6920.86
477_L617_I0.6920.86
154_E500_H0.6870.86
644_E657_V0.6850.85
482_S650_L0.6850.85
175_R178_A0.6850.85
480_V650_L0.6840.85
480_V491_L0.6840.85
625_G645_L0.6830.85
653_A656_A0.6820.85
154_E496_V0.6800.85
492_V595_V0.6780.85
271_E283_D0.6770.85
499_A505_V0.6760.85
531_G539_D0.6760.85
474_V614_V0.6730.84
160_A163_F0.6720.84
194_F417_H0.6720.84
438_V509_A0.6710.84
176_D181_A0.6710.84
328_G331_L0.6700.84
304_Q308_I0.6700.84
471_V593_S0.6700.84
306_V312_D0.6680.84
546_R596_F0.6670.84
198_E213_P0.6670.84
472_D617_I0.6640.84
457_L464_T0.6630.84
354_G357_A0.6630.84
272_L282_L0.6620.83
623_E645_L0.6610.83
606_D610_F0.6590.83
527_T601_A0.6590.83
443_G513_P0.6580.83
589_E611_G0.6550.83
310_G382_V0.6530.83
214_A503_L0.6530.83
580_I596_F0.6510.82
272_L283_D0.6500.82
273_D282_L0.6500.82
315_S319_R0.6500.82
392_R396_G0.6470.82
497_V500_H0.6470.82
170_I527_T0.6460.82
347_E372_V0.6460.82
208_D212_R0.6460.82
175_R196_G0.6460.82
307_T313_L0.6450.82
272_L280_N0.6450.82
328_G349_Q0.6450.82
449_I492_V0.6450.82
270_D273_D0.6450.82
395_A402_A0.6440.82
194_F421_E0.6430.82
528_L539_D0.6420.82
154_E515_I0.6390.81
586_A655_G0.6380.81
275_L288_D0.6370.81
543_L569_S0.6360.81
276_T286_V0.6350.81
144_R413_E0.6340.81
188_V232_I0.6330.81
301_I305_D0.6320.81
472_D475_A0.6310.80
216_V220_R0.6310.80
168_V196_G0.6300.80
271_E287_S0.6290.80
276_T281_D0.6290.80
277_R287_S0.6290.80
153_A204_R0.6260.80
446_G511_R0.6260.80
333_D343_R0.6240.80
353_R356_A0.6230.80
203_V213_P0.6230.80
254_D258_A0.6230.80
311_A315_S0.6220.79
289_A395_A0.6220.79
171_V532_A0.6210.79
173_D178_A0.6200.79
235_A259_H0.6190.79
186_T424_V0.6180.79
420_L424_V0.6180.79
427_A430_R0.6170.79
207_P443_G0.6170.79
272_L279_V0.6150.79
271_E277_R0.6150.79
272_L288_D0.6140.79
567_L583_I0.6130.78
227_A231_R0.6130.78
438_V505_V0.6120.78
297_L397_R0.6120.78
489_L520_Y0.6110.78
196_G200_E0.6100.78
121_P125_V0.6090.78
156_Y520_Y0.6080.78
493_A541_A0.6080.78
250_L256_A0.6080.78
272_L275_L0.6070.78
488_T492_V0.6070.78
270_D278_A0.6070.78
647_V652_E0.6070.78
277_R288_D0.6070.78
271_E281_D0.6040.77
332_A336_D0.6040.77
203_V207_P0.6030.77
210_M500_H0.6030.77
338_A342_A0.6020.77
428_V431_F0.6020.77
281_D287_S0.6010.77
160_A167_S0.6010.77
574_G640_R0.6000.77
564_V583_I0.5990.77
577_A597_V0.5990.77
275_L287_S0.5970.77
273_D286_V0.5960.77
609_G613_T0.5960.77
619_A639_A0.5950.76
132_V143_V0.5950.76
198_E428_V0.5950.76
334_E375_D0.5940.76
343_R346_L0.5930.76
443_G559_S0.5930.76
487_S490_D0.5930.76
169_E176_D0.5920.76
272_L278_A0.5920.76
339_V364_F0.5910.76
167_S170_I0.5910.76
316_L319_R0.5910.76
654_D657_V0.5910.76
216_V219_E0.5910.76
409_R413_E0.5900.76
482_S646_I0.5890.76
276_T284_A0.5890.76
197_V421_E0.5890.76
569_S580_I0.5880.76
253_L256_A0.5870.75
237_S240_E0.5870.75
517_E555_E0.5870.75
220_R425_A0.5870.75
338_A341_A0.5860.75
277_R411_P0.5860.75
495_V512_V0.5860.75
185_T430_R0.5850.75
157_S160_A0.5850.75
377_D380_A0.5840.75
244_I249_D0.5810.75
250_L402_A0.5810.75
482_S528_L0.5790.74
214_A512_V0.5790.74
437_C494_V0.5790.74
403_A406_A0.5790.74
183_G503_L0.5780.74
241_A244_I0.5780.74
550_D562_V0.5770.74
444_G511_R0.5760.74
591_G613_T0.5760.74
227_A262_G0.5750.74
264_G268_G0.5740.74
175_R181_A0.5730.74
397_R400_E0.5730.74
204_R518_L0.5720.74
556_S587_L0.5700.73
418_D421_E0.5700.73
324_D329_R0.5690.73
597_V621_G0.5690.73
167_S196_G0.5690.73
197_V239_H0.5670.73
328_G353_R0.5670.73
344_D373_A0.5670.73
120_T124_D0.5670.73
177_L180_L0.5670.73
185_T435_F0.5660.73
608_C616_G0.5660.73
492_V496_V0.5640.73
260_L264_G0.5630.72
216_V421_E0.5630.72
258_A273_D0.5610.72
308_I390_R0.5610.72
245_D405_L0.5590.72
274_R404_T0.5590.72
297_L400_E0.5580.72
325_S353_R0.5570.72
247_D398_K0.5570.72
293_A301_I0.5560.71
532_A631_R0.5550.71
491_L495_V0.5550.71
474_V592_A0.5550.71
539_D569_S0.5530.71
290_E394_A0.5530.71
154_E203_V0.5520.71
497_V501_M0.5520.71
173_D177_L0.5520.71
119_R123_D0.5520.71
579_I640_R0.5510.71
144_R417_H0.5500.71
380_A383_R0.5500.71
563_L618_H0.5490.71
172_E176_D0.5490.71
476_L584_L0.5490.71
622_L628_V0.5490.71
120_T221_V0.5470.70
300_A304_Q0.5470.70
245_D253_L0.5460.70
297_L302_G0.5460.70
402_A405_L0.5460.70
639_A642_T0.5450.70
274_R279_V0.5440.70
426_L430_R0.5440.70
324_D327_L0.5440.70
432_A504_P0.5440.70
250_L253_L0.5430.70
355_E358_K0.5430.70
564_V575_A0.5420.70
168_V172_E0.5420.70
464_T567_L0.5410.69
199_V498_L0.5400.69
577_A584_L0.5400.69
317_V321_A0.5390.69
335_Y338_A0.5390.69
312_D315_S0.5390.69
161_A201_G0.5380.69
326_L333_D0.5380.69
236_V241_A0.5370.69
327_L330_E0.5370.69
129_L143_V0.5370.69
134_P137_A0.5360.69
619_A645_L0.5360.69
574_G619_A0.5360.69
228_N266_V0.5360.69
180_L196_G0.5350.69
247_D289_A0.5350.69
178_A232_I0.5350.69
543_L546_R0.5350.69
510_A514_A0.5350.69
190_L416_V0.5350.69
165_E170_I0.5350.69
183_G437_C0.5340.68
190_L419_A0.5320.68
496_V513_P0.5320.68
496_V500_H0.5310.68
293_A296_R0.5300.68
145_E554_E0.5290.68
230_D234_A0.5290.68
317_V333_D0.5280.68
482_S573_P0.5280.68
536_T573_P0.5280.68
237_S569_S0.5270.67
568_E641_S0.5260.67
207_P500_H0.5250.67
278_A285_A0.5250.67
292_V398_K0.5240.67
354_G362_R0.5240.67
481_N599_H0.5240.67
201_G488_T0.5240.67
483_G619_A0.5240.67
265_S441_E0.5230.67
569_S576_S0.5220.67
459_V462_A0.5220.67
399_R403_A0.5210.67
190_L409_R0.5210.67
428_V626_E0.5200.66
342_A383_R0.5200.66
375_D379_M0.5200.66
183_G199_V0.5200.66
266_V269_D0.5190.66
171_V537_L0.5190.66
343_R349_Q0.5190.66
275_L281_D0.5190.66
206_E212_R0.5180.66
314_L321_A0.5180.66
157_S581_A0.5180.66
574_G605_R0.5180.66
329_R352_L0.5170.66
392_R395_A0.5170.66
318_E334_E0.5170.66
340_G394_A0.5160.66
329_R349_Q0.5160.66
581_A584_L0.5150.66
437_C503_L0.5140.66
308_I382_V0.5140.66
262_G266_V0.5140.66
373_A629_V0.5130.65
274_R287_S0.5130.65
483_G631_R0.5120.65
581_A607_Q0.5120.65
407_D444_G0.5120.65
341_A345_A0.5110.65
298_R397_R0.5110.65
508_E511_R0.5110.65
270_D284_A0.5100.65
165_E168_V0.5100.65
639_A645_L0.5100.65
256_A260_L0.5100.65
345_A349_Q0.5090.65
157_S549_D0.5090.65
474_V613_T0.5090.65
384_E389_A0.5090.65
483_G637_H0.5080.65
347_E351_G0.5080.65
605_R638_L0.5080.65
449_I496_V0.5080.65
337_D364_F0.5080.65
274_R280_N0.5080.65
325_S357_A0.5070.64
208_D441_E0.5070.64
358_K361_R0.5060.64
521_Y546_R0.5060.64
198_E375_D0.5060.64
442_R445_R0.5060.64
498_L501_M0.5060.64
528_L546_R0.5060.64
263_D422_V0.5040.64
308_I578_K0.5020.64
192_E427_A0.5020.64
321_A331_L0.5020.64
341_A348_E0.5020.64
291_S294_N0.5010.64
304_Q307_T0.5000.63
343_R379_M0.5000.63
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1wb9A 2 0.9522 100 0.351 Contact Map
3thxA 1 0.9297 100 0.351 Contact Map
2o8bB 1 0.9417 100 0.361 Contact Map
3thxB 1 0.9537 100 0.383 Contact Map
1ewqA 2 0.9447 100 0.391 Contact Map
2r8rA 1 0.2541 99 0.937 Contact Map
4uxhA 3 0.2436 98.8 0.941 Contact Map
4hseA 1 0.3244 98.7 0.943 Contact Map
4rvcA 4 0.296 98.7 0.943 Contact Map
2i3bA 1 0.2048 98.7 0.943 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0135 seconds.