GREMLIN Database
Q9HN17 - 4-hydroxybutyrate CoA transferase
UniProt: Q9HN17 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 491 (480)
Sequences: 808 (423)
Seq/√Len: 19.3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
129_D162_D5.0531.00
471_R485_T4.5931.00
35_L65_L4.5231.00
137_A166_V3.9731.00
292_Y351_L3.9601.00
137_A145_L3.7671.00
305_A334_Y3.5621.00
366_V432_V3.5351.00
436_H458_A3.4941.00
288_E310_A3.4941.00
366_V415_V3.3971.00
141_G144_W3.3631.00
482_D485_T3.3601.00
87_V99_A3.3051.00
469_L473_R3.1760.99
249_E283_S3.1700.99
466_R470_D3.1380.99
57_A86_G3.0810.99
364_V377_V3.0490.99
250_R254_R2.9990.99
196_V351_L2.9310.99
455_E466_R2.9270.99
215_L218_V2.8780.99
55_A58_R2.8450.99
34_T66_T2.7090.98
305_A326_R2.6220.98
457_A465_L2.5770.98
58_R83_A2.5490.97
30_A33_A2.5290.97
419_A422_V2.4830.97
451_E466_R2.4250.96
325_D329_D2.4010.96
285_A288_E2.3970.96
170_D220_R2.3480.96
20_K217_A2.3240.95
135_V158_V2.3200.95
139_A146_I2.3130.95
29_I53_L2.3090.95
175_G332_E2.3060.95
455_E462_R2.2900.95
66_T88_A2.2290.94
285_A308_D2.1810.93
10_A19_V2.1690.93
471_R482_D2.1460.93
166_V215_L2.1280.93
20_K28_G2.1040.92
151_V182_V2.0790.92
205_E209_R2.0750.92
93_Y268_V2.0510.91
467_A471_R2.0420.91
467_A485_T2.0410.91
323_G326_R2.0220.90
49_V219_V2.0160.90
415_V432_V2.0050.90
11_G177_S2.0020.90
57_A84_A2.0020.90
360_V402_A1.9980.90
197_S201_E1.9970.90
144_W207_A1.9840.90
420_S487_F1.9720.89
371_H479_L1.9250.88
109_A445_P1.9190.88
147_P208_V1.9170.88
243_N438_V1.9020.88
64_A88_A1.8860.87
415_V434_T1.8520.86
148_S172_Q1.8480.86
116_A349_P1.8470.86
452_A455_E1.8450.86
235_A238_R1.8390.86
81_L86_G1.8390.86
138_V148_S1.8250.85
37_V67_V1.8170.85
464_D489_W1.8130.85
85_G102_A1.8000.84
99_A108_L1.7900.84
364_V383_I1.7880.84
302_D326_R1.7740.83
172_Q176_L1.7660.83
11_G139_A1.7460.82
447_V477_G1.7450.82
21_D24_T1.7440.82
102_A108_L1.7400.82
35_L132_V1.7370.82
170_D222_D1.7300.82
168_V220_R1.6980.81
244_V400_V1.6960.81
200_G311_V1.6950.81
403_L414_T1.6930.80
238_R281_G1.6900.80
418_L481_H1.6850.80
28_G216_R1.6500.79
196_V201_E1.6370.78
109_A448_A1.6260.78
451_E470_D1.6250.78
210_F215_L1.6130.77
405_A435_E1.6010.76
363_A403_L1.5660.75
436_H462_R1.5650.75
91_Y118_L1.5580.74
193_P197_S1.5520.74
252_V260_A1.5500.74
227_P321_V1.5480.74
451_E455_E1.5170.72
314_A340_L1.5050.72
196_V203_V1.5020.72
183_V194_L1.5000.72
485_T488_D1.4970.71
139_A177_S1.4680.70
85_G107_E1.4650.70
436_H456_C1.4610.69
280_S306_D1.4590.69
369_Y472_A1.4550.69
163_E216_R1.4540.69
95_A268_V1.4530.69
146_I207_A1.4450.69
34_T68_V1.4360.68
467_A482_D1.4290.68
137_A154_T1.4280.68
23_T55_A1.4240.67
405_A458_A1.4110.67
330_A333_R1.4090.67
246_T253_D1.3990.66
450_A469_L1.3880.65
43_V316_S1.3660.64
246_T250_R1.3560.64
244_V433_V1.3380.62
123_R185_R1.3370.62
120_D188_P1.3340.62
89_R448_A1.3140.61
313_S339_V1.3140.61
65_L81_L1.3110.61
304_L309_L1.3080.61
398_L478_H1.3050.60
68_V130_P1.3030.60
301_L327_V1.3020.60
37_V134_V1.2990.60
79_T82_V1.2990.60
291_Y309_L1.2970.60
368_L453_I1.2940.60
164_V214_K1.2870.59
235_A239_R1.2760.59
238_R461_F1.2710.58
15_G210_F1.2700.58
164_V211_D1.2660.58
238_R242_D1.2640.58
158_V210_F1.2580.58
259_G285_A1.2570.58
15_G215_L1.2530.57
302_D323_G1.2510.57
171_A222_D1.2500.57
418_L456_C1.2460.57
144_W209_R1.2450.57
82_V102_A1.2440.57
453_I456_C1.2400.56
203_V345_V1.2330.56
327_V331_P1.2280.56
75_D83_A1.2280.56
37_V69_S1.2250.56
159_R184_V1.2200.55
283_S308_D1.2170.55
270_S404_P1.2140.55
51_R80_D1.2020.54
451_E469_L1.1950.54
425_T428_D1.1950.54
110_F268_V1.1880.53
87_V102_A1.1870.53
252_V282_S1.1820.53
324_Q328_F1.1780.53
11_G141_G1.1770.52
145_L166_V1.1730.52
145_L154_T1.1730.52
302_D305_A1.1680.52
36_A130_P1.1650.52
155_P184_V1.1630.52
333_R336_E1.1580.51
378_S487_F1.1550.51
418_L422_V1.1540.51
445_P448_A1.1530.51
53_L86_G1.1470.51
299_G318_A1.1470.51
311_V339_V1.1430.50
119_S153_Q1.1340.50
123_R344_N1.1310.50
49_V165_V1.1290.49
369_Y481_H1.1250.49
149_T172_Q1.1210.49
252_V258_I1.1170.49
29_I65_L1.1070.48
249_E284_L1.1030.48
230_F268_V1.1030.48
304_L337_D1.1010.48
262_P397_H1.1000.48
216_R220_R1.0890.47
149_T317_L1.0840.47
131_D162_D1.0830.47
250_R253_D1.0820.46
158_V164_V1.0790.46
48_A221_T1.0770.46
405_A436_H1.0720.46
240_I438_V1.0710.46
42_S73_V1.0710.46
242_D246_T1.0700.46
371_H393_N1.0640.45
173_P328_F1.0610.45
150_S343_S1.0600.45
88_A109_A1.0570.45
33_A132_V1.0570.45
123_R184_V1.0450.44
407_A410_G1.0450.44
63_L86_G1.0390.44
463_P466_R1.0370.44
232_D368_L1.0370.44
57_A63_L1.0360.44
88_A108_L1.0340.43
375_T382_L1.0340.43
73_V230_F1.0220.43
390_V424_H1.0170.42
29_I132_V1.0130.42
246_T249_E1.0110.42
447_V469_L1.0070.42
24_T27_A0.9960.41
305_A333_R0.9960.41
173_P331_P0.9940.41
137_A168_V0.9940.41
42_S268_V0.9930.41
99_A102_A0.9920.41
31_D57_A0.9860.40
200_G310_A0.9840.40
29_I134_V0.9820.40
319_L377_V0.9760.40
248_L282_S0.9750.40
28_G217_A0.9650.39
46_P301_L0.9640.39
368_L454_I0.9640.39
93_Y317_L0.9620.39
20_K24_T0.9590.39
173_P327_V0.9580.39
199_P368_L0.9580.39
106_R447_V0.9580.39
358_V398_L0.9580.39
322_D325_D0.9560.39
412_V461_F0.9550.39
37_V77_L0.9530.38
28_G132_V0.9520.38
50_P176_L0.9510.38
42_S228_Y0.9510.38
54_A81_L0.9480.38
426_E478_H0.9470.38
10_A168_V0.9460.38
290_R310_A0.9430.38
217_A257_V0.9370.37
33_A131_D0.9300.37
300_L318_A0.9300.37
183_V203_V0.9300.37
15_G218_V0.9230.37
194_L203_V0.9170.36
126_R397_H0.9150.36
79_T98_A0.9140.36
444_K452_A0.9140.36
196_V489_W0.9130.36
407_A435_E0.9130.36
173_P324_Q0.9110.36
123_R155_P0.9090.36
169_N221_T0.9070.36
292_Y313_S0.9070.36
280_S303_L0.9030.35
42_S96_T0.9020.35
177_S207_A0.9020.35
237_D427_H0.9000.35
43_V210_F0.8970.35
141_G146_I0.8950.35
120_D124_F0.8930.35
13_V16_D0.8870.35
24_T253_D0.8850.34
94_Q427_H0.8840.34
393_N479_L0.8800.34
236_T404_P0.8710.34
260_A288_E0.8710.34
153_Q157_Y0.8650.33
383_I479_L0.8640.33
179_F293_G0.8610.33
350_S354_R0.8610.33
291_Y299_G0.8600.33
229_E317_L0.8560.33
42_S226_D0.8500.32
138_V172_Q0.8490.32
76_P226_D0.8490.32
188_P404_P0.8430.32
71_G115_I0.8420.32
135_V154_T0.8410.32
95_A110_F0.8410.32
198_A201_E0.8410.32
186_D192_G0.8390.32
241_A444_K0.8380.32
134_V213_E0.8360.32
201_E254_R0.8330.32
455_E470_D0.8300.31
158_V208_V0.8300.31
156_A160_A0.8270.31
134_V462_R0.8260.31
119_S159_R0.8230.31
263_T456_C0.8170.31
100_R372_V0.8140.30
22_A52_A0.8140.30
236_T301_L0.8130.30
245_L282_S0.8120.30
234_T237_D0.8100.30
45_D75_D0.8090.30
271_L309_L0.8080.30
83_A98_A0.8040.30
244_V281_G0.8040.30
97_T101_T0.8020.30
376_H380_A0.8010.30
158_V211_D0.7970.30
219_V359_A0.7960.30
30_A213_E0.7950.29
68_V91_Y0.7940.29
114_G394_R0.7920.29
81_L128_V0.7890.29
168_V315_T0.7890.29
436_H455_E0.7880.29
113_R118_L0.7860.29
264_L357_V0.7850.29
156_A344_N0.7850.29
219_V445_P0.7850.29
93_Y382_L0.7850.29
79_T83_A0.7840.29
166_V314_A0.7830.29
192_G197_S0.7830.29
237_D425_T0.7820.29
248_L358_V0.7820.29
43_V293_G0.7800.29
305_A430_D0.7790.29
250_R406_T0.7780.29
291_Y362_S0.7770.29
253_D431_V0.7760.28
323_G327_V0.7760.28
14_N17_C0.7750.28
53_L393_N0.7750.28
23_T474_E0.7740.28
95_A228_Y0.7700.28
282_S396_A0.7690.28
18_P213_E0.7660.28
271_L418_L0.7660.28
406_T463_P0.7650.28
406_T460_A0.7650.28
53_L57_A0.7650.28
371_H419_A0.7650.28
154_T343_S0.7630.28
50_P78_D0.7620.28
12_R15_G0.7620.28
249_E253_D0.7610.28
154_T166_V0.7610.28
45_D76_P0.7590.28
158_V326_R0.7590.28
469_L488_D0.7580.28
322_D352_I0.7540.27
301_L323_G0.7530.27
461_F474_E0.7500.27
183_V193_P0.7470.27
393_N398_L0.7450.27
407_A414_T0.7440.27
451_E473_R0.7420.27
168_V232_D0.7420.27
245_L489_W0.7420.27
55_A59_D0.7420.27
487_F490_Q0.7410.27
201_E336_E0.7370.26
151_V222_D0.7360.26
467_A470_D0.7360.26
91_Y111_A0.7360.26
139_A166_V0.7360.26
239_R478_H0.7350.26
163_E166_V0.7330.26
42_S45_D0.7300.26
123_R186_D0.7290.26
164_V216_R0.7290.26
240_I291_Y0.7240.26
127_L363_A0.7230.26
46_P188_P0.7230.26
162_D244_V0.7230.26
124_F188_P0.7220.26
46_P404_P0.7220.26
120_D237_D0.7220.26
137_A141_G0.7220.26
100_R370_G0.7210.26
299_G315_T0.7210.26
17_C359_A0.7200.26
34_T380_A0.7180.26
139_A345_V0.7180.26
188_P262_P0.7180.26
199_P290_R0.7150.25
366_V372_V0.7140.25
293_G300_L0.7140.25
18_P282_S0.7130.25
176_L321_V0.7130.25
82_V97_T0.7120.25
78_D372_V0.7120.25
117_G430_D0.7120.25
163_E253_D0.7100.25
15_G19_V0.7090.25
147_P271_L0.7090.25
231_R270_S0.7070.25
463_P469_L0.7060.25
475_S484_S0.7040.25
252_V278_A0.7040.25
418_L486_A0.7030.25
404_P414_T0.7020.25
141_G218_V0.7020.25
164_V213_E0.7000.25
376_H426_E0.6990.25
276_M402_A0.6980.25
66_T89_R0.6970.25
12_R215_L0.6960.25
237_D426_E0.6950.24
375_T424_H0.6940.24
53_L134_V0.6930.24
296_I352_I0.6930.24
45_D227_P0.6930.24
378_S420_S0.6910.24
251_A256_P0.6910.24
122_V127_L0.6900.24
137_A157_Y0.6900.24
438_V444_K0.6900.24
351_L355_F0.6860.24
24_T35_L0.6850.24
102_A105_E0.6850.24
14_N215_L0.6840.24
238_R248_L0.6840.24
122_V130_P0.6830.24
96_T324_Q0.6830.24
142_P200_G0.6830.24
172_Q321_V0.6820.24
49_V53_L0.6820.24
151_V173_P0.6810.24
78_D479_L0.6810.24
392_F396_A0.6800.24
94_Q425_T0.6800.24
42_S50_P0.6790.24
155_P185_R0.6790.24
436_H460_A0.6780.24
433_V438_V0.6780.24
146_I206_S0.6770.24
164_V359_A0.6750.24
271_L400_V0.6740.23
176_L195_A0.6740.23
308_D436_H0.6720.23
140_V260_A0.6700.23
273_N297_Q0.6690.23
237_D301_L0.6670.23
53_L63_L0.6670.23
74_G363_A0.6670.23
197_S213_E0.6660.23
122_V160_A0.6640.23
415_V435_E0.6640.23
316_S444_K0.6640.23
13_V222_D0.6610.23
256_P355_F0.6610.23
366_V453_I0.6600.23
226_D293_G0.6600.23
245_L279_L0.6590.23
133_A161_A0.6580.23
360_V400_V0.6570.23
23_T359_A0.6570.23
12_R463_P0.6570.23
270_S414_T0.6550.23
305_A330_A0.6540.23
19_V450_A0.6530.23
94_Q426_E0.6530.23
58_R64_A0.6510.22
146_I474_E0.6500.22
85_G108_L0.6500.22
71_G234_T0.6500.22
10_A253_D0.6460.22
174_M177_S0.6460.22
485_T489_W0.6460.22
239_R242_D0.6460.22
8_G11_G0.6460.22
330_A445_P0.6450.22
235_A325_D0.6440.22
53_L65_L0.6440.22
37_V50_P0.6430.22
383_I408_A0.6430.22
199_P311_V0.6400.22
38_S41_G0.6390.22
151_V316_S0.6350.22
266_F276_M0.6340.22
146_I284_L0.6340.22
27_A217_A0.6340.22
12_R409_G0.6340.22
349_P396_A0.6330.22
432_V441_L0.6330.22
18_P239_R0.6330.22
344_N410_G0.6320.22
95_A221_T0.6310.22
137_A208_V0.6300.22
102_A107_E0.6300.22
16_D215_L0.6300.22
141_G210_F0.6300.22
150_S225_D0.6290.21
230_F318_A0.6270.21
268_V317_L0.6270.21
18_P163_E0.6270.21
199_P279_L0.6270.21
154_T157_Y0.6250.21
93_Y292_Y0.6230.21
406_T435_E0.6220.21
133_A157_Y0.6210.21
258_I263_T0.6200.21
127_L162_D0.6200.21
241_A348_A0.6190.21
293_G314_A0.6190.21
73_V270_S0.6170.21
147_P471_R0.6170.21
303_L342_P0.6160.21
432_V453_I0.6150.21
84_A113_R0.6150.21
21_D332_E0.6130.21
93_Y424_H0.6120.21
16_D19_V0.6110.21
73_V268_V0.6100.21
109_A447_V0.6100.21
171_A227_P0.6100.21
276_M291_Y0.6090.21
34_T130_P0.6080.21
134_V281_G0.6070.21
164_V478_H0.6070.21
427_H478_H0.6050.20
170_D221_T0.6050.20
326_R330_A0.6050.20
173_P396_A0.6040.20
231_R319_L0.6040.20
34_T128_V0.6040.20
79_T128_V0.6020.20
403_L435_E0.6020.20
10_A140_V0.6010.20
41_G71_G0.6010.20
110_F226_D0.6010.20
208_V487_F0.5990.20
46_P270_S0.5970.20
474_E477_G0.5970.20
252_V284_L0.5970.20
173_P323_G0.5970.20
233_P277_G0.5970.20
414_T435_E0.5970.20
352_I368_L0.5960.20
89_R111_A0.5960.20
405_A415_V0.5960.20
120_D126_R0.5950.20
22_A48_A0.5940.20
380_A479_L0.5940.20
366_V433_V0.5930.20
463_P467_A0.5930.20
76_P268_V0.5930.20
245_L252_V0.5920.20
73_V96_T0.5890.20
376_H427_H0.5890.20
56_A344_N0.5880.20
42_S93_Y0.5870.20
309_L334_Y0.5870.20
450_A466_R0.5870.20
173_P248_L0.5850.20
400_V458_A0.5850.20
74_G425_T0.5830.20
110_F179_F0.5830.20
291_Y402_A0.5790.19
413_S490_Q0.5790.19
292_Y308_D0.5790.19
183_V345_V0.5780.19
231_R271_L0.5770.19
23_T478_H0.5770.19
226_D268_V0.5770.19
401_V479_L0.5760.19
241_A245_L0.5750.19
237_D315_T0.5740.19
432_V466_R0.5730.19
355_F456_C0.5720.19
71_G424_H0.5720.19
50_P77_L0.5710.19
293_G296_I0.5710.19
179_F338_V0.5710.19
396_A441_L0.5700.19
248_L357_V0.5700.19
75_D226_D0.5690.19
336_E466_R0.5680.19
240_I243_N0.5660.19
50_P172_Q0.5660.19
149_T171_A0.5640.19
463_P470_D0.5640.19
228_Y319_L0.5640.19
425_T487_F0.5610.19
152_G297_Q0.5610.19
21_D65_L0.5610.19
198_A250_R0.5590.19
19_V475_S0.5580.19
241_A402_A0.5580.19
145_L162_D0.5570.19
137_A316_S0.5570.19
95_A397_H0.5570.19
360_V463_P0.5560.19
249_E282_S0.5560.19
55_A250_R0.5560.19
248_L252_V0.5550.18
242_D281_G0.5550.18
100_R429_T0.5540.18
196_V199_P0.5540.18
155_P186_D0.5530.18
21_D25_V0.5530.18
342_P345_V0.5520.18
321_V378_S0.5520.18
23_T52_A0.5520.18
116_A342_P0.5510.18
229_E339_V0.5510.18
45_D237_D0.5510.18
263_T358_V0.5500.18
232_D329_D0.5500.18
31_D86_G0.5490.18
401_V408_A0.5480.18
138_V176_L0.5450.18
217_A324_Q0.5450.18
119_S155_P0.5450.18
123_R187_P0.5440.18
34_T279_L0.5440.18
242_D364_V0.5430.18
446_P468_Y0.5420.18
245_L276_M0.5420.18
261_A289_L0.5420.18
151_V340_L0.5420.18
95_A233_P0.5410.18
88_A448_A0.5390.18
45_D73_V0.5390.18
338_V359_A0.5390.18
56_A232_D0.5380.18
41_G72_S0.5380.18
246_T254_R0.5370.18
371_H401_V0.5370.18
284_L428_D0.5360.18
315_T343_S0.5340.18
245_L378_S0.5340.18
87_V311_V0.5330.18
35_L213_E0.5330.18
97_T348_A0.5330.18
93_Y486_A0.5330.18
147_P257_V0.5320.18
78_D100_R0.5320.18
140_V192_G0.5310.18
291_Y328_F0.5300.18
31_D109_A0.5300.18
35_L310_A0.5290.18
25_V69_S0.5280.17
283_S478_H0.5280.17
56_A242_D0.5270.17
126_R188_P0.5270.17
38_S72_S0.5270.17
178_A350_S0.5260.17
96_T226_D0.5250.17
114_G428_D0.5250.17
150_S261_A0.5250.17
193_P348_A0.5250.17
259_G451_E0.5250.17
293_G318_A0.5240.17
266_F299_G0.5240.17
280_S308_D0.5240.17
257_V289_L0.5240.17
151_V168_V0.5230.17
317_L344_N0.5230.17
211_D216_R0.5230.17
99_A122_V0.5220.17
63_L73_V0.5220.17
54_A206_S0.5220.17
431_V452_A0.5220.17
35_L150_S0.5210.17
37_V271_L0.5210.17
57_A81_L0.5190.17
364_V407_A0.5190.17
259_G296_I0.5190.17
338_V422_V0.5180.17
163_E217_A0.5180.17
350_S432_V0.5170.17
245_L278_A0.5170.17
122_V157_Y0.5170.17
43_V57_A0.5160.17
218_V311_V0.5160.17
201_E489_W0.5160.17
228_Y383_I0.5160.17
257_V282_S0.5150.17
393_N401_V0.5140.17
319_L327_V0.5140.17
226_D318_A0.5130.17
149_T302_D0.5130.17
254_R455_E0.5110.17
165_V217_A0.5110.17
300_L309_L0.5110.17
123_R363_A0.5110.17
284_L308_D0.5100.17
186_D348_A0.5100.17
359_A396_A0.5090.17
134_V461_F0.5080.17
13_V232_D0.5080.17
326_R482_D0.5080.17
276_M419_A0.5070.17
240_I398_L0.5060.17
149_T227_P0.5060.17
17_C451_E0.5060.17
177_S206_S0.5050.17
78_D408_A0.5050.17
344_N407_A0.5040.17
432_V469_L0.5040.17
172_Q227_P0.5040.17
242_D310_A0.5030.17
122_V237_D0.5020.17
472_A482_D0.5020.17
145_L157_Y0.5010.16
25_V100_R0.5010.16
137_A155_P0.5010.16
168_V185_R0.5000.16
258_I378_S0.5000.16
335_A485_T0.5000.16
148_S227_P0.5000.16
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2g39A 2 0.9817 100 0.393 Contact Map
4eu9A 2 0.9837 100 0.393 Contact Map
2nvvA 2 0.9613 100 0.408 Contact Map
3qliA 2 0.8452 100 0.593 Contact Map
3eh7A 2 0.7862 100 0.596 Contact Map
2oasA 3 0.8289 100 0.601 Contact Map
3gk7A 2 0.8574 100 0.608 Contact Map
3d3uA 1 0.7576 100 0.608 Contact Map
2hj0A 2 0.888 100 0.645 Contact Map
1xr4A 2 0.8574 100 0.657 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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