Q9HN17 - HALSA - GREMLIN Contacts

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Q9HN17 - 4-hydroxybutyrate CoA transferase

UniProt:	Q9HN17	Sequences: MTAPRTAGVAGRVNGDCPVKDATTVAAGIADDATLAVSGFGSVGDPKAVPRALAAAARDGRDLALTVVSGGSVGDPLDTDLVAAGGVARRYPYQATTAARTAANERELAFADRGIAGLSDEVRFGRLVDPDVAVVEAVAVGPGWLIPSTSVGQTPAYVRAADEVVVEVNDAQPMGLSAFHDVVVRDPPPDRGPLAVSAPGERVGESAVRFDPEKLRAVVRTDRRDDPYEFRDPTATDRRIADNVLTVLERAVDRDPVIGAAPTLQFGVGSLGNALMGALSGSSLADGELRYYGEVIQDGLLDLLADGDLAVASATSLALSVDGQDRVFDAPERYAEDVVLRPSNVSNAPSLIDRFGVVAVNSAVGVDLYGHVNSTHVSGARLINGIGGSVDFNRNAHLTVVALPATAAGGDVSTVVPLASHVDHTEHDTDVVVTEHGVADLRGKPPVARAEAIIECAAPAFRPDLRAYLDRARESSGHLPHDLSTAFDWQS	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	491 (480)
Sequences:	808 (423)
Seq/√Len:	19.3

ECOLI - SCPC
HALSA - Q9HN17

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
129_D	162_D	5.053	1.00
471_R	485_T	4.593	1.00
35_L	65_L	4.523	1.00
137_A	166_V	3.973	1.00
292_Y	351_L	3.960	1.00
137_A	145_L	3.767	1.00
305_A	334_Y	3.562	1.00
366_V	432_V	3.535	1.00
436_H	458_A	3.494	1.00
288_E	310_A	3.494	1.00
366_V	415_V	3.397	1.00
141_G	144_W	3.363	1.00
482_D	485_T	3.360	1.00
87_V	99_A	3.305	1.00
469_L	473_R	3.176	0.99
249_E	283_S	3.170	0.99
466_R	470_D	3.138	0.99
57_A	86_G	3.081	0.99
364_V	377_V	3.049	0.99
250_R	254_R	2.999	0.99
196_V	351_L	2.931	0.99
455_E	466_R	2.927	0.99
215_L	218_V	2.878	0.99
55_A	58_R	2.845	0.99
34_T	66_T	2.709	0.98
305_A	326_R	2.622	0.98
457_A	465_L	2.577	0.98
58_R	83_A	2.549	0.97
30_A	33_A	2.529	0.97
419_A	422_V	2.483	0.97
451_E	466_R	2.425	0.96
325_D	329_D	2.401	0.96
285_A	288_E	2.397	0.96
170_D	220_R	2.348	0.96
20_K	217_A	2.324	0.95
135_V	158_V	2.320	0.95
139_A	146_I	2.313	0.95
29_I	53_L	2.309	0.95
175_G	332_E	2.306	0.95
455_E	462_R	2.290	0.95
66_T	88_A	2.229	0.94
285_A	308_D	2.181	0.93
10_A	19_V	2.169	0.93
471_R	482_D	2.146	0.93
166_V	215_L	2.128	0.93
20_K	28_G	2.104	0.92
151_V	182_V	2.079	0.92
205_E	209_R	2.075	0.92
93_Y	268_V	2.051	0.91
467_A	471_R	2.042	0.91
467_A	485_T	2.041	0.91
323_G	326_R	2.022	0.90
49_V	219_V	2.016	0.90
415_V	432_V	2.005	0.90
11_G	177_S	2.002	0.90
57_A	84_A	2.002	0.90
360_V	402_A	1.998	0.90
197_S	201_E	1.997	0.90
144_W	207_A	1.984	0.90
420_S	487_F	1.972	0.89
371_H	479_L	1.925	0.88
109_A	445_P	1.919	0.88
147_P	208_V	1.917	0.88
243_N	438_V	1.902	0.88
64_A	88_A	1.886	0.87
415_V	434_T	1.852	0.86
148_S	172_Q	1.848	0.86
116_A	349_P	1.847	0.86
452_A	455_E	1.845	0.86
235_A	238_R	1.839	0.86
81_L	86_G	1.839	0.86
138_V	148_S	1.825	0.85
37_V	67_V	1.817	0.85
464_D	489_W	1.813	0.85
85_G	102_A	1.800	0.84
99_A	108_L	1.790	0.84
364_V	383_I	1.788	0.84
302_D	326_R	1.774	0.83
172_Q	176_L	1.766	0.83
11_G	139_A	1.746	0.82
447_V	477_G	1.745	0.82
21_D	24_T	1.744	0.82
102_A	108_L	1.740	0.82
35_L	132_V	1.737	0.82
170_D	222_D	1.730	0.82
168_V	220_R	1.698	0.81
244_V	400_V	1.696	0.81
200_G	311_V	1.695	0.81
403_L	414_T	1.693	0.80
238_R	281_G	1.690	0.80
418_L	481_H	1.685	0.80
28_G	216_R	1.650	0.79
196_V	201_E	1.637	0.78
109_A	448_A	1.626	0.78
451_E	470_D	1.625	0.78
210_F	215_L	1.613	0.77
405_A	435_E	1.601	0.76
363_A	403_L	1.566	0.75
436_H	462_R	1.565	0.75
91_Y	118_L	1.558	0.74
193_P	197_S	1.552	0.74
252_V	260_A	1.550	0.74
227_P	321_V	1.548	0.74
451_E	455_E	1.517	0.72
314_A	340_L	1.505	0.72
196_V	203_V	1.502	0.72
183_V	194_L	1.500	0.72
485_T	488_D	1.497	0.71
139_A	177_S	1.468	0.70
85_G	107_E	1.465	0.70
436_H	456_C	1.461	0.69
280_S	306_D	1.459	0.69
369_Y	472_A	1.455	0.69
163_E	216_R	1.454	0.69
95_A	268_V	1.453	0.69
146_I	207_A	1.445	0.69
34_T	68_V	1.436	0.68
467_A	482_D	1.429	0.68
137_A	154_T	1.428	0.68
23_T	55_A	1.424	0.67
405_A	458_A	1.411	0.67
330_A	333_R	1.409	0.67
246_T	253_D	1.399	0.66
450_A	469_L	1.388	0.65
43_V	316_S	1.366	0.64
246_T	250_R	1.356	0.64
244_V	433_V	1.338	0.62
123_R	185_R	1.337	0.62
120_D	188_P	1.334	0.62
89_R	448_A	1.314	0.61
313_S	339_V	1.314	0.61
65_L	81_L	1.311	0.61
304_L	309_L	1.308	0.61
398_L	478_H	1.305	0.60
68_V	130_P	1.303	0.60
301_L	327_V	1.302	0.60
37_V	134_V	1.299	0.60
79_T	82_V	1.299	0.60
291_Y	309_L	1.297	0.60
368_L	453_I	1.294	0.60
164_V	214_K	1.287	0.59
235_A	239_R	1.276	0.59
238_R	461_F	1.271	0.58
15_G	210_F	1.270	0.58
164_V	211_D	1.266	0.58
238_R	242_D	1.264	0.58
158_V	210_F	1.258	0.58
259_G	285_A	1.257	0.58
15_G	215_L	1.253	0.57
302_D	323_G	1.251	0.57
171_A	222_D	1.250	0.57
418_L	456_C	1.246	0.57
144_W	209_R	1.245	0.57
82_V	102_A	1.244	0.57
453_I	456_C	1.240	0.56
203_V	345_V	1.233	0.56
327_V	331_P	1.228	0.56
75_D	83_A	1.228	0.56
37_V	69_S	1.225	0.56
159_R	184_V	1.220	0.55
283_S	308_D	1.217	0.55
270_S	404_P	1.214	0.55
51_R	80_D	1.202	0.54
451_E	469_L	1.195	0.54
425_T	428_D	1.195	0.54
110_F	268_V	1.188	0.53
87_V	102_A	1.187	0.53
252_V	282_S	1.182	0.53
324_Q	328_F	1.178	0.53
11_G	141_G	1.177	0.52
145_L	166_V	1.173	0.52
145_L	154_T	1.173	0.52
302_D	305_A	1.168	0.52
36_A	130_P	1.165	0.52
155_P	184_V	1.163	0.52
333_R	336_E	1.158	0.51
378_S	487_F	1.155	0.51
418_L	422_V	1.154	0.51
445_P	448_A	1.153	0.51
53_L	86_G	1.147	0.51
299_G	318_A	1.147	0.51
311_V	339_V	1.143	0.50
119_S	153_Q	1.134	0.50
123_R	344_N	1.131	0.50
49_V	165_V	1.129	0.49
369_Y	481_H	1.125	0.49
149_T	172_Q	1.121	0.49
252_V	258_I	1.117	0.49
29_I	65_L	1.107	0.48
249_E	284_L	1.103	0.48
230_F	268_V	1.103	0.48
304_L	337_D	1.101	0.48
262_P	397_H	1.100	0.48
216_R	220_R	1.089	0.47
149_T	317_L	1.084	0.47
131_D	162_D	1.083	0.47
250_R	253_D	1.082	0.46
158_V	164_V	1.079	0.46
48_A	221_T	1.077	0.46
405_A	436_H	1.072	0.46
240_I	438_V	1.071	0.46
42_S	73_V	1.071	0.46
242_D	246_T	1.070	0.46
371_H	393_N	1.064	0.45
173_P	328_F	1.061	0.45
150_S	343_S	1.060	0.45
88_A	109_A	1.057	0.45
33_A	132_V	1.057	0.45
123_R	184_V	1.045	0.44
407_A	410_G	1.045	0.44
63_L	86_G	1.039	0.44
463_P	466_R	1.037	0.44
232_D	368_L	1.037	0.44
57_A	63_L	1.036	0.44
88_A	108_L	1.034	0.43
375_T	382_L	1.034	0.43
73_V	230_F	1.022	0.43
390_V	424_H	1.017	0.42
29_I	132_V	1.013	0.42
246_T	249_E	1.011	0.42
447_V	469_L	1.007	0.42
24_T	27_A	0.996	0.41
305_A	333_R	0.996	0.41
173_P	331_P	0.994	0.41
137_A	168_V	0.994	0.41
42_S	268_V	0.993	0.41
99_A	102_A	0.992	0.41
31_D	57_A	0.986	0.40
200_G	310_A	0.984	0.40
29_I	134_V	0.982	0.40
319_L	377_V	0.976	0.40
248_L	282_S	0.975	0.40
28_G	217_A	0.965	0.39
46_P	301_L	0.964	0.39
368_L	454_I	0.964	0.39
93_Y	317_L	0.962	0.39
20_K	24_T	0.959	0.39
173_P	327_V	0.958	0.39
199_P	368_L	0.958	0.39
106_R	447_V	0.958	0.39
358_V	398_L	0.958	0.39
322_D	325_D	0.956	0.39
412_V	461_F	0.955	0.39
37_V	77_L	0.953	0.38
28_G	132_V	0.952	0.38
50_P	176_L	0.951	0.38
42_S	228_Y	0.951	0.38
54_A	81_L	0.948	0.38
426_E	478_H	0.947	0.38
10_A	168_V	0.946	0.38
290_R	310_A	0.943	0.38
217_A	257_V	0.937	0.37
33_A	131_D	0.930	0.37
300_L	318_A	0.930	0.37
183_V	203_V	0.930	0.37
15_G	218_V	0.923	0.37
194_L	203_V	0.917	0.36
126_R	397_H	0.915	0.36
79_T	98_A	0.914	0.36
444_K	452_A	0.914	0.36
196_V	489_W	0.913	0.36
407_A	435_E	0.913	0.36
173_P	324_Q	0.911	0.36
123_R	155_P	0.909	0.36
169_N	221_T	0.907	0.36
292_Y	313_S	0.907	0.36
280_S	303_L	0.903	0.35
42_S	96_T	0.902	0.35
177_S	207_A	0.902	0.35
237_D	427_H	0.900	0.35
43_V	210_F	0.897	0.35
141_G	146_I	0.895	0.35
120_D	124_F	0.893	0.35
13_V	16_D	0.887	0.35
24_T	253_D	0.885	0.34
94_Q	427_H	0.884	0.34
393_N	479_L	0.880	0.34
236_T	404_P	0.871	0.34
260_A	288_E	0.871	0.34
153_Q	157_Y	0.865	0.33
383_I	479_L	0.864	0.33
179_F	293_G	0.861	0.33
350_S	354_R	0.861	0.33
291_Y	299_G	0.860	0.33
229_E	317_L	0.856	0.33
42_S	226_D	0.850	0.32
138_V	172_Q	0.849	0.32
76_P	226_D	0.849	0.32
188_P	404_P	0.843	0.32
71_G	115_I	0.842	0.32
135_V	154_T	0.841	0.32
95_A	110_F	0.841	0.32
198_A	201_E	0.841	0.32
186_D	192_G	0.839	0.32
241_A	444_K	0.838	0.32
134_V	213_E	0.836	0.32
201_E	254_R	0.833	0.32
455_E	470_D	0.830	0.31
158_V	208_V	0.830	0.31
156_A	160_A	0.827	0.31
134_V	462_R	0.826	0.31
119_S	159_R	0.823	0.31
263_T	456_C	0.817	0.31
100_R	372_V	0.814	0.30
22_A	52_A	0.814	0.30
236_T	301_L	0.813	0.30
245_L	282_S	0.812	0.30
234_T	237_D	0.810	0.30
45_D	75_D	0.809	0.30
271_L	309_L	0.808	0.30
83_A	98_A	0.804	0.30
244_V	281_G	0.804	0.30
97_T	101_T	0.802	0.30
376_H	380_A	0.801	0.30
158_V	211_D	0.797	0.30
219_V	359_A	0.796	0.30
30_A	213_E	0.795	0.29
68_V	91_Y	0.794	0.29
114_G	394_R	0.792	0.29
81_L	128_V	0.789	0.29
168_V	315_T	0.789	0.29
436_H	455_E	0.788	0.29
113_R	118_L	0.786	0.29
264_L	357_V	0.785	0.29
156_A	344_N	0.785	0.29
219_V	445_P	0.785	0.29
93_Y	382_L	0.785	0.29
79_T	83_A	0.784	0.29
166_V	314_A	0.783	0.29
192_G	197_S	0.783	0.29
237_D	425_T	0.782	0.29
248_L	358_V	0.782	0.29
43_V	293_G	0.780	0.29
305_A	430_D	0.779	0.29
250_R	406_T	0.778	0.29
291_Y	362_S	0.777	0.29
253_D	431_V	0.776	0.28
323_G	327_V	0.776	0.28
14_N	17_C	0.775	0.28
53_L	393_N	0.775	0.28
23_T	474_E	0.774	0.28
95_A	228_Y	0.770	0.28
282_S	396_A	0.769	0.28
18_P	213_E	0.766	0.28
271_L	418_L	0.766	0.28
406_T	463_P	0.765	0.28
406_T	460_A	0.765	0.28
53_L	57_A	0.765	0.28
371_H	419_A	0.765	0.28
154_T	343_S	0.763	0.28
50_P	78_D	0.762	0.28
12_R	15_G	0.762	0.28
249_E	253_D	0.761	0.28
154_T	166_V	0.761	0.28
45_D	76_P	0.759	0.28
158_V	326_R	0.759	0.28
469_L	488_D	0.758	0.28
322_D	352_I	0.754	0.27
301_L	323_G	0.753	0.27
461_F	474_E	0.750	0.27
183_V	193_P	0.747	0.27
393_N	398_L	0.745	0.27
407_A	414_T	0.744	0.27
451_E	473_R	0.742	0.27
168_V	232_D	0.742	0.27
245_L	489_W	0.742	0.27
55_A	59_D	0.742	0.27
487_F	490_Q	0.741	0.27
201_E	336_E	0.737	0.26
151_V	222_D	0.736	0.26
467_A	470_D	0.736	0.26
91_Y	111_A	0.736	0.26
139_A	166_V	0.736	0.26
239_R	478_H	0.735	0.26
163_E	166_V	0.733	0.26
42_S	45_D	0.730	0.26
123_R	186_D	0.729	0.26
164_V	216_R	0.729	0.26
240_I	291_Y	0.724	0.26
127_L	363_A	0.723	0.26
46_P	188_P	0.723	0.26
162_D	244_V	0.723	0.26
124_F	188_P	0.722	0.26
46_P	404_P	0.722	0.26
120_D	237_D	0.722	0.26
137_A	141_G	0.722	0.26
100_R	370_G	0.721	0.26
299_G	315_T	0.721	0.26
17_C	359_A	0.720	0.26
34_T	380_A	0.718	0.26
139_A	345_V	0.718	0.26
188_P	262_P	0.718	0.26
199_P	290_R	0.715	0.25
366_V	372_V	0.714	0.25
293_G	300_L	0.714	0.25
18_P	282_S	0.713	0.25
176_L	321_V	0.713	0.25
82_V	97_T	0.712	0.25
78_D	372_V	0.712	0.25
117_G	430_D	0.712	0.25
163_E	253_D	0.710	0.25
15_G	19_V	0.709	0.25
147_P	271_L	0.709	0.25
231_R	270_S	0.707	0.25
463_P	469_L	0.706	0.25
475_S	484_S	0.704	0.25
252_V	278_A	0.704	0.25
418_L	486_A	0.703	0.25
404_P	414_T	0.702	0.25
141_G	218_V	0.702	0.25
164_V	213_E	0.700	0.25
376_H	426_E	0.699	0.25
276_M	402_A	0.698	0.25
66_T	89_R	0.697	0.25
12_R	215_L	0.696	0.25
237_D	426_E	0.695	0.24
375_T	424_H	0.694	0.24
53_L	134_V	0.693	0.24
296_I	352_I	0.693	0.24
45_D	227_P	0.693	0.24
378_S	420_S	0.691	0.24
251_A	256_P	0.691	0.24
122_V	127_L	0.690	0.24
137_A	157_Y	0.690	0.24
438_V	444_K	0.690	0.24
351_L	355_F	0.686	0.24
24_T	35_L	0.685	0.24
102_A	105_E	0.685	0.24
14_N	215_L	0.684	0.24
238_R	248_L	0.684	0.24
122_V	130_P	0.683	0.24
96_T	324_Q	0.683	0.24
142_P	200_G	0.683	0.24
172_Q	321_V	0.682	0.24
49_V	53_L	0.682	0.24
151_V	173_P	0.681	0.24
78_D	479_L	0.681	0.24
392_F	396_A	0.680	0.24
94_Q	425_T	0.680	0.24
42_S	50_P	0.679	0.24
155_P	185_R	0.679	0.24
436_H	460_A	0.678	0.24
433_V	438_V	0.678	0.24
146_I	206_S	0.677	0.24
164_V	359_A	0.675	0.24
271_L	400_V	0.674	0.23
176_L	195_A	0.674	0.23
308_D	436_H	0.672	0.23
140_V	260_A	0.670	0.23
273_N	297_Q	0.669	0.23
237_D	301_L	0.667	0.23
53_L	63_L	0.667	0.23
74_G	363_A	0.667	0.23
197_S	213_E	0.666	0.23
122_V	160_A	0.664	0.23
415_V	435_E	0.664	0.23
316_S	444_K	0.664	0.23
13_V	222_D	0.661	0.23
256_P	355_F	0.661	0.23
366_V	453_I	0.660	0.23
226_D	293_G	0.660	0.23
245_L	279_L	0.659	0.23
133_A	161_A	0.658	0.23
360_V	400_V	0.657	0.23
23_T	359_A	0.657	0.23
12_R	463_P	0.657	0.23
270_S	414_T	0.655	0.23
305_A	330_A	0.654	0.23
19_V	450_A	0.653	0.23
94_Q	426_E	0.653	0.23
58_R	64_A	0.651	0.22
146_I	474_E	0.650	0.22
85_G	108_L	0.650	0.22
71_G	234_T	0.650	0.22
10_A	253_D	0.646	0.22
174_M	177_S	0.646	0.22
485_T	489_W	0.646	0.22
239_R	242_D	0.646	0.22
8_G	11_G	0.646	0.22
330_A	445_P	0.645	0.22
235_A	325_D	0.644	0.22
53_L	65_L	0.644	0.22
37_V	50_P	0.643	0.22
383_I	408_A	0.643	0.22
199_P	311_V	0.640	0.22
38_S	41_G	0.639	0.22
151_V	316_S	0.635	0.22
266_F	276_M	0.634	0.22
146_I	284_L	0.634	0.22
27_A	217_A	0.634	0.22
12_R	409_G	0.634	0.22
349_P	396_A	0.633	0.22
432_V	441_L	0.633	0.22
18_P	239_R	0.633	0.22
344_N	410_G	0.632	0.22
95_A	221_T	0.631	0.22
137_A	208_V	0.630	0.22
102_A	107_E	0.630	0.22
16_D	215_L	0.630	0.22
141_G	210_F	0.630	0.22
150_S	225_D	0.629	0.21
230_F	318_A	0.627	0.21
268_V	317_L	0.627	0.21
18_P	163_E	0.627	0.21
199_P	279_L	0.627	0.21
154_T	157_Y	0.625	0.21
93_Y	292_Y	0.623	0.21
406_T	435_E	0.622	0.21
133_A	157_Y	0.621	0.21
258_I	263_T	0.620	0.21
127_L	162_D	0.620	0.21
241_A	348_A	0.619	0.21
293_G	314_A	0.619	0.21
73_V	270_S	0.617	0.21
147_P	471_R	0.617	0.21
303_L	342_P	0.616	0.21
432_V	453_I	0.615	0.21
84_A	113_R	0.615	0.21
21_D	332_E	0.613	0.21
93_Y	424_H	0.612	0.21
16_D	19_V	0.611	0.21
73_V	268_V	0.610	0.21
109_A	447_V	0.610	0.21
171_A	227_P	0.610	0.21
276_M	291_Y	0.609	0.21
34_T	130_P	0.608	0.21
134_V	281_G	0.607	0.21
164_V	478_H	0.607	0.21
427_H	478_H	0.605	0.20
170_D	221_T	0.605	0.20
326_R	330_A	0.605	0.20
173_P	396_A	0.604	0.20
231_R	319_L	0.604	0.20
34_T	128_V	0.604	0.20
79_T	128_V	0.602	0.20
403_L	435_E	0.602	0.20
10_A	140_V	0.601	0.20
41_G	71_G	0.601	0.20
110_F	226_D	0.601	0.20
208_V	487_F	0.599	0.20
46_P	270_S	0.597	0.20
474_E	477_G	0.597	0.20
252_V	284_L	0.597	0.20
173_P	323_G	0.597	0.20
233_P	277_G	0.597	0.20
414_T	435_E	0.597	0.20
352_I	368_L	0.596	0.20
89_R	111_A	0.596	0.20
405_A	415_V	0.596	0.20
120_D	126_R	0.595	0.20
22_A	48_A	0.594	0.20
380_A	479_L	0.594	0.20
366_V	433_V	0.593	0.20
463_P	467_A	0.593	0.20
76_P	268_V	0.593	0.20
245_L	252_V	0.592	0.20
73_V	96_T	0.589	0.20
376_H	427_H	0.589	0.20
56_A	344_N	0.588	0.20
42_S	93_Y	0.587	0.20
309_L	334_Y	0.587	0.20
450_A	466_R	0.587	0.20
173_P	248_L	0.585	0.20
400_V	458_A	0.585	0.20
74_G	425_T	0.583	0.20
110_F	179_F	0.583	0.20
291_Y	402_A	0.579	0.19
413_S	490_Q	0.579	0.19
292_Y	308_D	0.579	0.19
183_V	345_V	0.578	0.19
231_R	271_L	0.577	0.19
23_T	478_H	0.577	0.19
226_D	268_V	0.577	0.19
401_V	479_L	0.576	0.19
241_A	245_L	0.575	0.19
237_D	315_T	0.574	0.19
432_V	466_R	0.573	0.19
355_F	456_C	0.572	0.19
71_G	424_H	0.572	0.19
50_P	77_L	0.571	0.19
293_G	296_I	0.571	0.19
179_F	338_V	0.571	0.19
396_A	441_L	0.570	0.19
248_L	357_V	0.570	0.19
75_D	226_D	0.569	0.19
336_E	466_R	0.568	0.19
240_I	243_N	0.566	0.19
50_P	172_Q	0.566	0.19
149_T	171_A	0.564	0.19
463_P	470_D	0.564	0.19
228_Y	319_L	0.564	0.19
425_T	487_F	0.561	0.19
152_G	297_Q	0.561	0.19
21_D	65_L	0.561	0.19
198_A	250_R	0.559	0.19
19_V	475_S	0.558	0.19
241_A	402_A	0.558	0.19
145_L	162_D	0.557	0.19
137_A	316_S	0.557	0.19
95_A	397_H	0.557	0.19
360_V	463_P	0.556	0.19
249_E	282_S	0.556	0.19
55_A	250_R	0.556	0.19
248_L	252_V	0.555	0.18
242_D	281_G	0.555	0.18
100_R	429_T	0.554	0.18
196_V	199_P	0.554	0.18
155_P	186_D	0.553	0.18
21_D	25_V	0.553	0.18
342_P	345_V	0.552	0.18
321_V	378_S	0.552	0.18
23_T	52_A	0.552	0.18
116_A	342_P	0.551	0.18
229_E	339_V	0.551	0.18
45_D	237_D	0.551	0.18
263_T	358_V	0.550	0.18
232_D	329_D	0.550	0.18
31_D	86_G	0.549	0.18
401_V	408_A	0.548	0.18
138_V	176_L	0.545	0.18
217_A	324_Q	0.545	0.18
119_S	155_P	0.545	0.18
123_R	187_P	0.544	0.18
34_T	279_L	0.544	0.18
242_D	364_V	0.543	0.18
446_P	468_Y	0.542	0.18
245_L	276_M	0.542	0.18
261_A	289_L	0.542	0.18
151_V	340_L	0.542	0.18
95_A	233_P	0.541	0.18
88_A	448_A	0.539	0.18
45_D	73_V	0.539	0.18
338_V	359_A	0.539	0.18
56_A	232_D	0.538	0.18
41_G	72_S	0.538	0.18
246_T	254_R	0.537	0.18
371_H	401_V	0.537	0.18
284_L	428_D	0.536	0.18
315_T	343_S	0.534	0.18
245_L	378_S	0.534	0.18
87_V	311_V	0.533	0.18
35_L	213_E	0.533	0.18
97_T	348_A	0.533	0.18
93_Y	486_A	0.533	0.18
147_P	257_V	0.532	0.18
78_D	100_R	0.532	0.18
140_V	192_G	0.531	0.18
291_Y	328_F	0.530	0.18
31_D	109_A	0.530	0.18
35_L	310_A	0.529	0.18
25_V	69_S	0.528	0.17
283_S	478_H	0.528	0.17
56_A	242_D	0.527	0.17
126_R	188_P	0.527	0.17
38_S	72_S	0.527	0.17
178_A	350_S	0.526	0.17
96_T	226_D	0.525	0.17
114_G	428_D	0.525	0.17
150_S	261_A	0.525	0.17
193_P	348_A	0.525	0.17
259_G	451_E	0.525	0.17
293_G	318_A	0.524	0.17
266_F	299_G	0.524	0.17
280_S	308_D	0.524	0.17
257_V	289_L	0.524	0.17
151_V	168_V	0.523	0.17
317_L	344_N	0.523	0.17
211_D	216_R	0.523	0.17
99_A	122_V	0.522	0.17
63_L	73_V	0.522	0.17
54_A	206_S	0.522	0.17
431_V	452_A	0.522	0.17
35_L	150_S	0.521	0.17
37_V	271_L	0.521	0.17
57_A	81_L	0.519	0.17
364_V	407_A	0.519	0.17
259_G	296_I	0.519	0.17
338_V	422_V	0.518	0.17
163_E	217_A	0.518	0.17
350_S	432_V	0.517	0.17
245_L	278_A	0.517	0.17
122_V	157_Y	0.517	0.17
43_V	57_A	0.516	0.17
218_V	311_V	0.516	0.17
201_E	489_W	0.516	0.17
228_Y	383_I	0.516	0.17
257_V	282_S	0.515	0.17
393_N	401_V	0.514	0.17
319_L	327_V	0.514	0.17
226_D	318_A	0.513	0.17
149_T	302_D	0.513	0.17
254_R	455_E	0.511	0.17
165_V	217_A	0.511	0.17
300_L	309_L	0.511	0.17
123_R	363_A	0.511	0.17
284_L	308_D	0.510	0.17
186_D	348_A	0.510	0.17
359_A	396_A	0.509	0.17
134_V	461_F	0.508	0.17
13_V	232_D	0.508	0.17
326_R	482_D	0.508	0.17
276_M	419_A	0.507	0.17
240_I	398_L	0.506	0.17
149_T	227_P	0.506	0.17
17_C	451_E	0.506	0.17
177_S	206_S	0.505	0.17
78_D	408_A	0.505	0.17
344_N	407_A	0.504	0.17
432_V	469_L	0.504	0.17
172_Q	227_P	0.504	0.17
242_D	310_A	0.503	0.17
122_V	237_D	0.502	0.17
472_A	482_D	0.502	0.17
145_L	157_Y	0.501	0.16
25_V	100_R	0.501	0.16
137_A	155_P	0.501	0.16
168_V	185_R	0.500	0.16
258_I	378_S	0.500	0.16
335_A	485_T	0.500	0.16
148_S	227_P	0.500	0.16

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2g39A	2	0.9817	100	0.393	Contact Map
4eu9A	2	0.9837	100	0.393	Contact Map
2nvvA	2	0.9613	100	0.408	Contact Map
3qliA	2	0.8452	100	0.593	Contact Map
3eh7A	2	0.7862	100	0.596	Contact Map
2oasA	3	0.8289	100	0.601	Contact Map
3gk7A	2	0.8574	100	0.608	Contact Map
3d3uA	1	0.7576	100	0.608	Contact Map
2hj0A	2	0.888	100	0.645	Contact Map
1xr4A	2	0.8574	100	0.657	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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