Q9HN16 - HALSA - GREMLIN Contacts

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Q9HN16 - Uncharacterized protein

UniProt:	Q9HN16	Sequences: MSRTLRLSAIRPSWLPAGLDARRLVLFWSAVAGVLVPVYFLVLADVSHLAWDYRAYHAAAEAALHGDPFVGIETGLPGVSYVYPPVAVALFVPQAAAGGWQTAFAIQSACNVAAALGLAALTVHTIEARRGRLDDIDRLLVVGFCVASAPVLSALGLGQVDTLIALALAGTFVALERDHQGIAGVVIAAAALVKVFPVVLGLWLVFRRAWHAIGVAVATATGALVAGGLWFGVDAYIRYVHVLAARSRVSEFAGTVSPDFFAMSLYRPLSQLLGTVDPRLYGPLALLAVAPAVWFVARREHTLTDRLTTYLAVVAGMLLVSPASNALYVVYAYFPLVCLLYLDPGGRERWLLLAGTAAMAFPVQPAHVAAGLASLGAPSTASHAVLAVVAPVLSVASVPLLGLSAVLVWCTIHTAGRHVPLTTAHTAASGD	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	431 (368)
Sequences:	1679 (1346)
Seq/√Len:	70.2

HALSA - Q9HN16

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
192_L	223_A	5.389	1.00
192_L	224_L	5.215	1.00
61_E	65_H	4.511	1.00
53_Y	103_A	4.225	1.00
185_V	219_T	4.036	1.00
111_N	162_T	3.708	1.00
167_A	190_A	3.601	1.00
62_A	67_D	3.493	1.00
64_L	95_A	3.419	1.00
191_A	198_V	3.169	1.00
293_V	316_G	3.133	1.00
68_P	71_G	3.081	1.00
97_A	102_T	3.056	1.00
215_V	219_T	2.871	1.00
60_A	93_P	2.865	1.00
86_V	223_A	2.861	1.00
60_A	92_V	2.606	1.00
60_A	91_F	2.534	1.00
63_A	231_F	2.508	1.00
121_L	166_L	2.430	1.00
114_A	166_L	2.425	1.00
98_G	102_T	2.424	1.00
69_F	88_V	2.421	1.00
118_L	165_A	2.381	1.00
294_W	298_R	2.331	1.00
284_L	288_A	2.244	1.00
196_F	328_Y	2.136	1.00
171_T	187_I	2.136	1.00
222_G	226_A	2.119	1.00
110_C	163_L	2.114	1.00
214_G	218_A	2.101	1.00
287_L	291_P	2.051	1.00
83_Y	161_D	2.037	1.00
161_D	328_Y	2.005	1.00
314_V	318_L	1.996	1.00
183_A	209_A	1.967	1.00
199_V	317_M	1.953	1.00
188_A	219_T	1.926	1.00
262_A	325_N	1.922	1.00
298_R	302_T	1.916	1.00
297_A	313_V	1.850	1.00
179_H	183_A	1.842	1.00
262_A	267_R	1.839	1.00
64_L	96_A	1.834	1.00
116_L	142_V	1.817	1.00
209_A	212_A	1.817	1.00
184_G	188_A	1.800	1.00
223_A	227_G	1.761	1.00
114_A	163_L	1.759	1.00
228_G	235_A	1.723	1.00
84_P	322_P	1.715	1.00
353_L	357_A	1.708	1.00
124_H	129_R	1.704	1.00
323_A	327_L	1.695	1.00
352_L	356_T	1.686	1.00
283_P	287_L	1.667	1.00
197_P	328_Y	1.660	0.99
160_V	164_I	1.660	0.99
315_A	402_G	1.658	0.99
199_V	202_L	1.658	0.99
200_L	314_V	1.619	0.99
55_A	83_Y	1.611	0.99
235_A	239_Y	1.610	0.99
179_H	182_I	1.602	0.99
393_L	396_A	1.580	0.99
82_V	328_Y	1.569	0.99
81_Y	87_A	1.565	0.99
82_V	250_S	1.561	0.99
53_Y	107_Q	1.561	0.99
356_T	360_A	1.524	0.99
281_Y	285_A	1.510	0.99
95_A	98_G	1.501	0.99
106_I	109_A	1.501	0.99
70_V	81_Y	1.497	0.99
363_V	366_A	1.494	0.99
309_T	313_V	1.474	0.99
111_N	163_L	1.468	0.99
63_A	92_V	1.452	0.99
325_N	328_Y	1.432	0.98
308_T	311_L	1.429	0.98
83_Y	194_K	1.427	0.98
154_A	161_D	1.419	0.98
224_L	227_G	1.416	0.98
218_A	222_G	1.414	0.98
269_L	274_G	1.395	0.98
227_G	232_G	1.393	0.98
106_I	110_C	1.381	0.98
163_L	166_L	1.371	0.98
30_A	33_G	1.366	0.98
161_D	330_V	1.365	0.98
51_W	79_V	1.349	0.98
232_G	235_A	1.343	0.98
102_T	106_I	1.340	0.98
191_A	220_A	1.328	0.98
364_Q	367_H	1.326	0.97
264_S	267_R	1.320	0.97
60_A	88_V	1.316	0.97
64_L	92_V	1.310	0.97
192_L	227_G	1.310	0.97
201_G	216_A	1.307	0.97
143_G	147_A	1.294	0.97
295_F	299_R	1.293	0.97
411_T	414_T	1.286	0.97
409_W	412_I	1.285	0.97
166_L	170_G	1.284	0.97
396_A	399_P	1.275	0.97
57_H	103_A	1.271	0.97
394_S	397_S	1.265	0.97
262_A	328_Y	1.259	0.97
216_A	219_T	1.259	0.97
159_Q	322_P	1.257	0.97
168_L	171_T	1.246	0.96
117_G	166_L	1.239	0.96
149_A	326_A	1.239	0.96
215_V	218_A	1.231	0.96
211_H	215_V	1.228	0.96
323_A	328_Y	1.226	0.96
205_V	213_I	1.225	0.96
388_V	391_P	1.224	0.96
56_Y	59_A	1.219	0.96
118_L	169_A	1.219	0.96
283_P	290_A	1.214	0.96
56_Y	91_F	1.214	0.96
107_Q	163_L	1.211	0.96
25_V	225_V	1.208	0.96
79_V	318_L	1.207	0.96
189_A	223_A	1.200	0.95
201_G	210_W	1.196	0.95
407_L	411_T	1.195	0.95
282_G	286_L	1.184	0.95
55_A	79_V	1.170	0.95
321_S	331_Y	1.167	0.95
116_L	120_A	1.166	0.95
59_A	82_V	1.166	0.95
188_A	220_A	1.163	0.95
30_A	40_F	1.160	0.95
360_A	364_Q	1.155	0.94
198_V	202_L	1.146	0.94
296_V	413_H	1.146	0.94
102_T	105_A	1.134	0.94
100_W	105_A	1.126	0.94
279_R	283_P	1.125	0.94
182_I	186_V	1.121	0.93
56_Y	82_V	1.121	0.93
412_I	415_A	1.115	0.93
292_A	296_V	1.110	0.93
321_S	325_N	1.109	0.93
117_G	414_T	1.107	0.93
50_A	104_F	1.102	0.93
204_L	216_A	1.101	0.93
83_Y	328_Y	1.100	0.93
266_Y	270_S	1.092	0.93
117_G	163_L	1.087	0.92
246_R	249_V	1.087	0.92
308_T	312_A	1.084	0.92
242_V	249_V	1.079	0.92
237_I	241_H	1.075	0.92
205_V	210_W	1.075	0.92
56_Y	83_Y	1.073	0.92
53_Y	94_Q	1.064	0.92
189_A	219_T	1.063	0.92
73_E	76_L	1.062	0.91
28_W	32_A	1.059	0.91
225_V	228_G	1.057	0.91
357_A	361_F	1.048	0.91
81_Y	88_V	1.043	0.91
120_A	124_H	1.041	0.91
204_L	207_R	1.039	0.91
190_A	197_P	1.031	0.90
358_A	361_F	1.031	0.90
82_V	246_R	1.027	0.90
159_Q	194_K	1.026	0.90
361_F	367_H	1.022	0.90
203_W	309_T	1.021	0.90
119_A	333_Y	1.020	0.90
93_P	96_A	1.015	0.90
281_Y	284_L	1.009	0.89
52_D	194_K	0.994	0.89
324_S	329_V	0.987	0.88
190_A	196_F	0.987	0.88
293_V	297_A	0.977	0.88
290_A	294_W	0.975	0.88
119_A	145_C	0.973	0.87
220_A	224_L	0.963	0.87
285_A	299_R	0.962	0.87
82_V	249_V	0.961	0.87
195_V	325_N	0.960	0.87
24_L	36_V	0.959	0.87
86_V	192_L	0.958	0.87
227_G	249_V	0.957	0.87
402_G	407_L	0.953	0.86
187_I	264_S	0.953	0.86
89_A	231_F	0.952	0.86
107_Q	157_L	0.948	0.86
178_D	183_A	0.947	0.86
154_A	162_T	0.947	0.86
262_A	327_L	0.943	0.86
149_A	161_D	0.942	0.86
118_L	166_L	0.942	0.86
295_F	298_R	0.936	0.85
55_A	82_V	0.934	0.85
232_G	236_Y	0.932	0.85
228_G	232_G	0.931	0.85
404_S	407_L	0.929	0.85
88_V	327_L	0.929	0.85
187_I	216_A	0.926	0.85
91_F	161_D	0.920	0.84
31_V	38_V	0.919	0.84
410_C	414_T	0.918	0.84
31_V	40_F	0.916	0.84
82_V	154_A	0.913	0.84
172_F	310_Y	0.912	0.84
80_S	84_P	0.909	0.84
81_Y	327_L	0.909	0.84
59_A	91_F	0.907	0.83
161_D	324_S	0.906	0.83
167_A	193_V	0.899	0.83
162_T	166_L	0.899	0.83
50_A	54_R	0.896	0.83
225_V	229_L	0.893	0.82
161_D	164_I	0.892	0.82
176_E	179_H	0.886	0.82
393_L	400_L	0.884	0.82
389_V	398_V	0.882	0.82
387_A	395_V	0.881	0.82
362_P	365_P	0.880	0.82
169_A	310_Y	0.879	0.81
386_L	389_V	0.878	0.81
88_V	323_A	0.876	0.81
294_W	297_A	0.874	0.81
153_S	157_L	0.872	0.81
143_G	146_V	0.870	0.81
28_W	35_L	0.869	0.81
160_V	328_Y	0.868	0.81
161_D	197_P	0.868	0.81
153_S	326_A	0.867	0.81
140_L	356_T	0.863	0.80
263_M	271_Q	0.862	0.80
164_I	190_A	0.862	0.80
25_V	39_Y	0.860	0.80
246_R	257_S	0.856	0.80
227_G	235_A	0.849	0.79
117_G	120_A	0.849	0.79
168_L	198_V	0.847	0.79
74_T	138_R	0.846	0.79
35_L	39_Y	0.844	0.79
195_V	199_V	0.843	0.79
32_A	40_F	0.841	0.79
56_Y	325_N	0.841	0.79
296_V	410_C	0.840	0.78
73_E	77_P	0.838	0.78
82_V	327_L	0.837	0.78
406_V	409_W	0.836	0.78
180_Q	209_A	0.836	0.78
51_W	80_S	0.830	0.78
79_V	325_N	0.828	0.77
112_V	155_L	0.825	0.77
28_W	31_V	0.823	0.77
81_Y	271_Q	0.823	0.77
70_V	82_V	0.822	0.77
387_A	391_P	0.819	0.77
86_V	189_A	0.818	0.77
177_R	182_I	0.817	0.77
389_V	403_L	0.816	0.76
201_G	213_I	0.813	0.76
59_A	81_Y	0.810	0.76
68_P	234_D	0.808	0.76
204_L	213_I	0.806	0.76
80_S	318_L	0.803	0.75
113_A	226_A	0.799	0.75
187_I	204_L	0.798	0.75
55_A	80_S	0.797	0.75
56_Y	331_Y	0.792	0.74
240_V	244_A	0.791	0.74
94_Q	103_A	0.790	0.74
181_G	215_V	0.790	0.74
24_L	27_F	0.787	0.74
161_D	196_F	0.786	0.74
52_D	328_Y	0.785	0.74
355_G	360_A	0.784	0.74
56_Y	328_Y	0.783	0.73
86_V	191_A	0.783	0.73
212_A	215_V	0.779	0.73
82_V	325_N	0.778	0.73
388_V	393_L	0.774	0.73
357_A	364_Q	0.771	0.72
324_S	327_L	0.771	0.72
82_V	196_F	0.768	0.72
311_L	314_V	0.766	0.72
262_A	323_A	0.765	0.72
392_V	395_V	0.764	0.72
204_L	313_V	0.763	0.71
34_V	42_V	0.759	0.71
149_A	398_V	0.758	0.71
36_V	42_V	0.756	0.71
402_G	406_V	0.755	0.71
52_D	325_N	0.755	0.71
342_L	346_G	0.753	0.70
280_L	284_L	0.752	0.70
168_L	331_Y	0.748	0.70
23_R	27_F	0.747	0.70
286_L	297_A	0.743	0.69
292_A	359_M	0.742	0.69
188_A	192_L	0.742	0.69
79_V	84_P	0.742	0.69
86_V	197_P	0.740	0.69
283_P	286_L	0.738	0.69
82_V	195_V	0.736	0.69
351_L	364_Q	0.733	0.68
56_Y	80_S	0.732	0.68
314_V	331_Y	0.731	0.68
97_A	106_I	0.731	0.68
102_T	167_A	0.731	0.68
362_P	367_H	0.729	0.68
31_V	100_W	0.729	0.68
56_Y	197_P	0.728	0.68
116_L	138_R	0.728	0.68
351_L	358_A	0.727	0.68
195_V	328_Y	0.727	0.68
403_L	414_T	0.725	0.68
400_L	409_W	0.721	0.67
197_P	262_A	0.719	0.67
30_A	34_V	0.719	0.67
138_R	162_T	0.718	0.67
27_F	217_V	0.717	0.67
181_G	211_H	0.715	0.67
392_V	396_A	0.714	0.66
238_R	242_V	0.714	0.66
148_S	151_V	0.714	0.66
33_G	42_V	0.711	0.66
88_V	196_F	0.711	0.66
122_T	169_A	0.710	0.66
144_F	358_A	0.708	0.66
387_A	392_V	0.707	0.66
267_R	321_S	0.705	0.65
202_L	207_R	0.705	0.65
192_L	220_A	0.703	0.65
204_L	258_P	0.702	0.65
84_P	399_P	0.702	0.65
159_Q	325_N	0.700	0.65
196_F	325_N	0.700	0.65
31_V	35_L	0.699	0.65
280_L	285_A	0.698	0.65
122_T	175_L	0.697	0.65
296_V	300_E	0.695	0.64
26_L	29_S	0.694	0.64
135_D	139_L	0.694	0.64
222_G	225_V	0.692	0.64
104_F	111_N	0.691	0.64
82_V	245_A	0.691	0.64
239_Y	246_R	0.687	0.63
401_L	404_S	0.686	0.63
86_V	188_A	0.684	0.63
218_A	394_S	0.682	0.63
97_A	213_I	0.681	0.63
307_L	338_C	0.681	0.63
233_V	359_M	0.681	0.63
84_P	197_P	0.679	0.63
319_L	399_P	0.679	0.63
80_S	186_V	0.677	0.62
203_W	213_I	0.677	0.62
56_Y	238_R	0.677	0.62
61_E	95_A	0.676	0.62
174_A	182_I	0.674	0.62
160_V	323_A	0.673	0.62
171_T	183_A	0.669	0.61
74_T	77_P	0.669	0.61
82_V	248_R	0.668	0.61
386_L	390_A	0.668	0.61
278_P	282_G	0.666	0.61
361_F	366_A	0.666	0.61
210_W	214_G	0.666	0.61
80_S	325_N	0.664	0.61
127_E	308_T	0.664	0.61
168_L	191_A	0.663	0.61
360_A	365_P	0.662	0.61
204_L	212_A	0.662	0.61
113_A	241_H	0.661	0.60
250_S	257_S	0.660	0.60
246_R	250_S	0.658	0.60
264_S	269_L	0.658	0.60
151_V	333_Y	0.656	0.60
245_A	248_R	0.650	0.59
26_L	34_V	0.648	0.59
191_A	201_G	0.647	0.59
292_A	316_G	0.647	0.59
310_Y	316_G	0.645	0.59
27_F	31_V	0.645	0.59
56_Y	159_Q	0.644	0.58
363_V	367_H	0.643	0.58
308_T	342_L	0.642	0.58
399_P	402_G	0.642	0.58
66_G	97_A	0.642	0.58
87_A	238_R	0.641	0.58
248_R	265_L	0.640	0.58
311_L	338_C	0.639	0.58
51_W	55_A	0.638	0.58
230_W	285_A	0.638	0.58
171_T	200_L	0.637	0.58
361_F	414_T	0.636	0.57
265_L	269_L	0.634	0.57
55_A	325_N	0.633	0.57
326_A	329_V	0.632	0.57
223_A	235_A	0.630	0.57
66_G	211_H	0.629	0.57
95_A	103_A	0.628	0.57
190_A	317_M	0.626	0.56
389_V	392_V	0.625	0.56
357_A	360_A	0.624	0.56
182_I	306_R	0.624	0.56
90_L	93_P	0.622	0.56
296_V	405_A	0.620	0.56
96_A	177_R	0.617	0.55
81_Y	259_D	0.615	0.55
171_T	190_A	0.614	0.55
196_F	327_L	0.614	0.55
361_F	364_Q	0.612	0.55
411_T	415_A	0.610	0.54
72_I	76_L	0.609	0.54
56_Y	195_V	0.608	0.54
22_R	119_A	0.608	0.54
262_A	271_Q	0.607	0.54
59_A	398_V	0.605	0.54
139_L	143_G	0.604	0.54
299_R	303_L	0.601	0.53
56_Y	324_S	0.600	0.53
312_A	318_L	0.600	0.53
36_V	40_F	0.599	0.53
150_P	271_Q	0.596	0.53
161_D	334_F	0.596	0.53
265_L	288_A	0.595	0.53
203_W	206_F	0.593	0.52
35_L	65_H	0.592	0.52
350_W	365_P	0.591	0.52
199_V	315_A	0.591	0.52
397_S	400_L	0.589	0.52
365_P	368_V	0.589	0.52
202_L	205_V	0.586	0.51
136_I	140_L	0.586	0.51
238_R	249_V	0.586	0.51
223_A	335_P	0.585	0.51
56_Y	327_L	0.584	0.51
84_P	184_G	0.583	0.51
359_M	362_P	0.582	0.51
154_A	210_W	0.580	0.51
81_Y	325_N	0.579	0.51
286_L	293_V	0.579	0.51
299_R	302_T	0.578	0.51
107_Q	111_N	0.578	0.51
396_A	400_L	0.578	0.51
359_M	414_T	0.577	0.50
111_N	154_A	0.576	0.50
107_Q	166_L	0.574	0.50
31_V	37_P	0.572	0.50
35_L	185_V	0.572	0.50
102_T	113_A	0.571	0.50
98_G	106_I	0.569	0.49
170_G	174_A	0.569	0.49
313_V	324_S	0.568	0.49
195_V	327_L	0.568	0.49
208_R	281_Y	0.567	0.49
94_Q	107_Q	0.567	0.49
23_R	26_L	0.566	0.49
25_V	30_A	0.565	0.49
385_V	388_V	0.564	0.49
348_E	351_L	0.564	0.49
71_G	221_T	0.563	0.49
265_L	285_A	0.562	0.49
322_P	328_Y	0.561	0.48
398_V	401_L	0.560	0.48
222_G	230_W	0.559	0.48
218_A	221_T	0.559	0.48
61_E	67_D	0.559	0.48
350_W	362_P	0.557	0.48
135_D	201_G	0.556	0.48
86_V	328_Y	0.556	0.48
352_L	360_A	0.556	0.48
305_D	308_T	0.555	0.48
400_L	404_S	0.555	0.48
221_T	359_M	0.555	0.48
262_A	321_S	0.552	0.47
52_D	159_Q	0.551	0.47
227_G	233_V	0.551	0.47
34_V	44_A	0.550	0.47
218_A	368_V	0.550	0.47
91_F	141_V	0.550	0.47
218_A	352_L	0.549	0.47
51_W	324_S	0.548	0.47
220_A	223_A	0.548	0.47
121_L	124_H	0.547	0.47
217_V	272_L	0.546	0.47
78_G	290_A	0.546	0.47
176_E	209_A	0.546	0.47
410_C	415_A	0.544	0.46
29_S	112_V	0.543	0.46
60_A	63_A	0.543	0.46
35_L	41_L	0.543	0.46
261_F	326_A	0.543	0.46
168_L	200_L	0.540	0.46
205_V	208_R	0.539	0.46
352_L	357_A	0.538	0.46
188_A	322_P	0.536	0.45
214_G	265_L	0.536	0.45
81_Y	161_D	0.535	0.45
55_A	331_Y	0.534	0.45
210_W	358_A	0.534	0.45
52_D	188_A	0.533	0.45
50_A	111_N	0.533	0.45
274_G	394_S	0.532	0.45
30_A	39_Y	0.531	0.45
198_V	201_G	0.529	0.45
29_S	35_L	0.529	0.45
397_S	405_A	0.528	0.44
111_N	116_L	0.527	0.44
210_W	213_I	0.527	0.44
191_A	197_P	0.526	0.44
50_A	271_Q	0.525	0.44
48_H	156_G	0.525	0.44
86_V	325_N	0.525	0.44
60_A	309_T	0.525	0.44
89_A	309_T	0.523	0.44
27_F	39_Y	0.523	0.44
271_Q	324_S	0.523	0.44
161_D	329_V	0.522	0.44
55_A	164_I	0.522	0.44
387_A	393_L	0.521	0.44
26_L	137_D	0.520	0.43
108_S	155_L	0.520	0.43
170_G	222_G	0.518	0.43
297_A	301_H	0.517	0.43
341_Y	345_G	0.516	0.43
322_P	325_N	0.515	0.43
34_V	40_F	0.515	0.43
395_V	400_L	0.515	0.43
378_P	397_S	0.513	0.43
266_Y	279_R	0.512	0.43
406_V	411_T	0.512	0.43
294_W	355_G	0.510	0.42
213_I	263_M	0.509	0.42
230_W	336_L	0.508	0.42
214_G	226_A	0.507	0.42
296_V	406_V	0.506	0.42
188_A	195_V	0.506	0.42
190_A	323_A	0.506	0.42
391_P	396_A	0.506	0.42
288_A	357_A	0.505	0.42
197_P	325_N	0.504	0.42
98_G	404_S	0.503	0.41
68_P	312_A	0.503	0.41
29_S	142_V	0.502	0.41
30_A	136_I	0.502	0.41
79_V	82_V	0.500	0.41

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3wajA	1	0.7935	94.1	0.919	Contact Map
3rceA	1	0.8097	17.6	0.96	Contact Map
2kluA	1	0.1183	7.4	0.966	Contact Map
2l2tA	2	0.1021	3.3	0.971	Contact Map
3wt9A	1	0.3387	3.3	0.971	Contact Map
2jwaA	2	0.1021	3.1	0.972	Contact Map
4p02A	1	0.2947	3	0.972	Contact Map
4ogqG	1	0.0858	2.7	0.973	Contact Map
2k1eA	3	0.2251	2	0.974	Contact Map
2m20A	2	0.109	1.9	0.975	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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