GREMLIN Database
Q9HN11 - Uncharacterized protein
UniProt: Q9HN11 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 162 (159)
Sequences: 120 (82)
Seq/√Len: 6.5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
13_V83_A4.0080.95
109_G136_V3.4490.89
111_L137_V2.9310.79
18_L42_V2.7270.74
145_A149_A2.5530.69
91_V95_V2.5040.67
28_G83_A2.4910.67
82_L87_D2.1900.56
17_L40_T2.0390.50
34_G53_V2.0090.49
51_R120_Q1.9490.47
36_E117_P1.9430.47
22_F30_V1.9290.46
61_L71_Q1.9220.46
4_F8_P1.8930.45
51_R132_P1.8860.45
3_K63_D1.8790.45
9_G46_A1.8500.44
49_D125_D1.8320.43
38_P142_L1.8310.43
38_P56_T1.8270.43
94_A133_R1.8180.42
103_I125_D1.7590.40
110_L152_E1.7130.39
120_Q125_D1.7000.38
25_N86_L1.6960.38
7_S92_T1.6620.37
24_V150_L1.6240.36
26_D57_T1.5900.34
14_I75_Q1.5830.34
58_E150_L1.5180.32
48_V84_P1.5100.32
53_V143_P1.5080.32
49_D120_Q1.4980.31
44_Q139_D1.4510.30
91_V124_E1.4470.30
105_A116_I1.4250.29
113_D149_A1.4200.29
49_D102_G1.4080.29
35_I156_V1.4000.28
123_S134_L1.3940.28
56_T83_A1.3930.28
4_F36_E1.3830.28
111_L136_V1.3820.28
70_F79_L1.3600.27
23_S135_Y1.3560.27
69_I77_P1.3320.26
5_E12_A1.3280.26
115_G136_V1.3190.26
114_H150_L1.3140.26
26_D71_Q1.2940.25
37_I73_I1.2920.25
98_A117_P1.2910.25
31_V92_T1.2760.25
37_I123_S1.2630.24
104_V121_T1.2610.24
146_V156_V1.2420.24
56_T72_N1.2310.24
16_L122_I1.2150.23
35_I52_V1.1980.23
113_D145_A1.1670.22
98_A120_Q1.1670.22
102_G125_D1.1540.22
75_Q121_T1.1480.21
146_V149_A1.1480.21
118_I141_E1.1400.21
8_P90_V1.1390.21
37_I137_V1.1310.21
94_A141_E1.1210.21
51_R91_V1.1150.21
112_A142_L1.0890.20
12_A93_V1.0730.20
84_P123_S1.0670.20
26_D44_Q1.0610.19
74_S105_A1.0500.19
32_S45_E1.0460.19
6_G55_S1.0440.19
44_Q87_D1.0370.19
114_H142_L1.0300.19
23_S39_Y1.0280.19
15_R126_P1.0230.18
64_G147_F1.0190.18
39_Y155_A1.0120.18
95_V110_L1.0110.18
38_P90_V1.0060.18
80_M111_L1.0040.18
95_V157_R0.9880.18
28_G56_T0.9840.18
49_D103_I0.9810.18
35_I141_E0.9630.17
91_V137_V0.9580.17
16_L32_S0.9430.17
47_G109_G0.9380.17
9_G53_V0.9370.17
121_T159_V0.9350.17
96_Q147_F0.9290.16
13_V48_V0.9180.16
12_A91_V0.9140.16
15_R161_L0.9110.16
29_R67_T0.9070.16
84_P88_L0.9050.16
120_Q132_P0.8960.16
115_G143_P0.8950.16
14_I130_D0.8900.16
44_Q72_N0.8680.15
42_V96_Q0.8620.15
91_V159_V0.8570.15
64_G159_V0.8520.15
2_Q101_P0.8520.15
10_Q129_T0.8410.15
93_V107_V0.8360.15
61_L113_D0.8330.15
14_I60_I0.8320.15
72_N94_A0.8310.15
23_S121_T0.8310.15
39_Y67_T0.8310.15
131_E160_E0.8270.15
46_A74_S0.8260.15
18_L52_V0.8210.14
149_A152_E0.8160.14
51_R61_L0.8120.14
64_G71_Q0.8120.14
69_I134_L0.8080.14
23_S107_V0.7940.14
17_L55_S0.7900.14
77_P92_T0.7890.14
10_Q14_I0.7880.14
25_N88_L0.7870.14
121_T138_T0.7850.14
79_L98_A0.7830.14
19_E72_N0.7810.14
102_G120_Q0.7790.14
29_R135_Y0.7740.14
16_L20_R0.7740.14
13_V156_V0.7630.13
2_Q113_D0.7570.13
42_V151_A0.7550.13
96_Q105_A0.7540.13
89_H141_E0.7510.13
39_Y54_D0.7480.13
75_Q92_T0.7480.13
76_I142_L0.7480.13
18_L65_E0.7470.13
61_L67_T0.7470.13
7_S31_V0.7420.13
87_D124_E0.7370.13
103_I120_Q0.7340.13
76_I136_V0.7170.13
108_T142_L0.7160.13
40_T161_L0.7140.13
89_H138_T0.7130.13
134_L153_M0.7130.13
23_S78_S0.7040.12
32_S123_S0.7030.12
9_G60_I0.7000.12
78_S135_Y0.6950.12
24_V130_D0.6950.12
15_R26_D0.6920.12
8_P36_E0.6920.12
30_V130_D0.6900.12
88_L139_D0.6900.12
114_H151_A0.6880.12
44_Q81_D0.6860.12
57_T92_T0.6820.12
47_G87_D0.6800.12
47_G90_V0.6760.12
49_D86_L0.6760.12
62_D161_L0.6730.12
40_T153_M0.6700.12
53_V150_L0.6700.12
110_L158_S0.6680.12
9_G94_A0.6680.12
51_R125_D0.6670.12
15_R62_D0.6670.12
74_S136_V0.6640.12
19_E116_I0.6600.12
16_L84_P0.6570.12
118_I137_V0.6530.12
34_G157_R0.6500.12
26_D34_G0.6490.12
47_G157_R0.6490.12
125_D132_P0.6460.12
12_A86_L0.6350.11
9_G29_R0.6300.11
17_L71_Q0.6290.11
23_S124_E0.6270.11
74_S87_D0.6230.11
12_A58_E0.6230.11
24_V57_T0.6210.11
112_A144_G0.6190.11
22_F57_T0.6170.11
13_V70_F0.6150.11
45_E123_S0.6140.11
101_P111_L0.6130.11
73_I141_E0.6110.11
73_I160_E0.6110.11
44_Q91_V0.6090.11
52_V88_L0.6010.11
144_G156_V0.5980.11
83_A128_F0.5950.11
5_E11_Q0.5950.11
10_Q22_F0.5950.11
87_D91_V0.5910.11
19_E69_I0.5840.11
57_T130_D0.5780.11
142_L152_E0.5760.10
20_R123_S0.5720.10
53_V93_V0.5690.10
13_V84_P0.5690.10
26_D86_L0.5610.10
16_L22_F0.5550.10
47_G85_V0.5550.10
19_E77_P0.5540.10
75_Q152_E0.5510.10
105_A139_D0.5500.10
108_T134_L0.5490.10
9_G70_F0.5430.10
93_V150_L0.5390.10
25_N61_L0.5390.10
37_I157_R0.5350.10
64_G161_L0.5340.10
37_I79_L0.5320.10
93_V152_E0.5310.10
24_V131_E0.5280.10
98_A132_P0.5230.10
151_A156_V0.5220.10
108_T146_V0.5200.10
49_D89_H0.5180.10
53_V115_G0.5160.10
117_P133_R0.5120.10
145_A161_L0.5110.10
45_E102_G0.5110.10
49_D54_D0.5100.10
94_A157_R0.5090.10
22_F54_D0.5060.10
105_A112_A0.5030.10
5_E147_F0.5010.10
56_T61_L0.5000.09
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1y7pA 5 0.4691 97.6 0.877 Contact Map
2ko1A 2 0.463 97.2 0.886 Contact Map
2pc6A 2 0.463 97 0.888 Contact Map
2f1fA 4 0.4568 96.7 0.892 Contact Map
1ygyA 4 0.8827 96.6 0.894 Contact Map
2lvwA 2 0.5062 96.2 0.898 Contact Map
2fgcA 2 0.463 95.9 0.901 Contact Map
1zpvA 3 0.4568 95.2 0.906 Contact Map
2cg4A 6 0.8086 95.1 0.906 Contact Map
3louA 3 0.4444 94.5 0.909 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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