Q9HMX7 - HALSA - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

Q9HMX7 - Uncharacterized protein

UniProt:	Q9HMX7	Sequences: MNAREVTGGREFVVRLDPGSEWRTELETLAATEDITAAWFTGLGAVQDAELWYYDQDDFEYTAAEFDEPLEVAACVGNIATLDGEPFAHTHATLSRRSGQALAGHLERATVFAGELYVRELDADLVREHDAATDLDRWL	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	139 (125)
Sequences:	718 (576)
Seq/√Len:	51.5

HALSA - Q9HMX7

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
12_F	29_L	4.469	1.00
96_R	100_Q	3.860	1.00
73_A	93_T	3.693	1.00
73_A	103_A	3.097	1.00
130_D	133_T	2.828	1.00
40_F	90_T	2.703	1.00
10_R	120_E	2.618	1.00
31_A	85_E	2.528	1.00
49_A	94_L	2.456	1.00
68_E	96_R	2.435	1.00
29_L	118_V	2.368	1.00
16_L	25_E	2.228	1.00
28_T	32_T	2.153	1.00
96_R	102_L	2.071	1.00
93_T	101_A	1.908	0.99
30_A	79_I	1.871	0.99
48_D	67_D	1.806	0.99
111_V	114_G	1.754	0.99
14_V	29_L	1.742	0.99
42_G	114_G	1.716	0.99
14_V	116_L	1.710	0.99
73_A	101_A	1.657	0.98
87_F	127_R	1.637	0.98
19_G	47_Q	1.630	0.98
21_E	24_T	1.594	0.98
72_V	114_G	1.577	0.98
21_E	109_A	1.548	0.97
42_G	116_L	1.539	0.97
51_L	92_A	1.525	0.97
22_W	46_V	1.512	0.97
42_G	75_C	1.488	0.97
29_L	33_E	1.476	0.97
22_W	114_G	1.438	0.96
92_A	106_L	1.425	0.96
54_Y	133_T	1.389	0.95
13_V	125_L	1.388	0.95
14_V	26_L	1.385	0.95
16_L	116_L	1.368	0.95
72_V	92_A	1.365	0.95
24_T	108_R	1.350	0.94
79_I	118_V	1.300	0.93
25_E	28_T	1.285	0.93
46_V	109_A	1.247	0.91
64_A	99_G	1.239	0.91
35_I	38_A	1.223	0.91
75_C	90_T	1.210	0.90
41_T	76_V	1.190	0.89
80_A	87_F	1.174	0.89
46_V	110_T	1.121	0.86
26_L	132_A	1.098	0.85
36_T	124_D	1.087	0.85
78_N	117_Y	1.082	0.84
55_D	62_T	1.054	0.83
63_A	107_E	1.051	0.83
45_A	135_L	1.045	0.82
18_P	45_A	1.043	0.82
46_V	72_V	1.040	0.82
40_F	75_C	1.018	0.81
55_D	58_D	1.018	0.81
73_A	76_V	1.011	0.80
43_L	76_V	1.009	0.80
21_E	110_T	1.004	0.80
22_W	72_V	1.004	0.80
53_Y	66_F	0.981	0.78
35_I	120_E	0.972	0.77
14_V	121_L	0.964	0.77
89_H	105_H	0.960	0.77
15_R	113_A	0.959	0.76
46_V	94_L	0.948	0.76
49_A	70_L	0.940	0.75
52_W	107_E	0.920	0.73
19_G	124_D	0.914	0.73
11_E	119_R	0.908	0.72
21_E	108_R	0.865	0.69
75_C	129_H	0.859	0.68
40_F	88_A	0.841	0.67
45_A	112_F	0.838	0.66
15_R	111_V	0.830	0.65
81_T	86_P	0.817	0.64
113_A	135_L	0.815	0.64
52_W	61_Y	0.811	0.64
70_L	94_L	0.809	0.63
56_Q	113_A	0.806	0.63
48_D	65_E	0.804	0.63
103_A	127_R	0.800	0.63
36_T	81_T	0.785	0.61
87_F	136_D	0.774	0.60
12_F	120_E	0.773	0.60
20_S	28_T	0.769	0.60
40_F	93_T	0.762	0.59
17_D	81_T	0.757	0.58
55_D	61_Y	0.756	0.58
31_A	34_D	0.751	0.58
45_A	54_Y	0.748	0.57
34_D	67_D	0.739	0.57
51_L	131_A	0.736	0.56
45_A	113_A	0.732	0.56
70_L	96_R	0.731	0.56
94_L	102_L	0.727	0.55
56_Q	112_F	0.724	0.55
41_T	80_A	0.722	0.55
40_F	118_V	0.716	0.54
46_V	92_A	0.713	0.54
50_E	65_E	0.705	0.53
45_A	52_W	0.701	0.53
24_T	28_T	0.695	0.52
12_F	33_E	0.694	0.52
25_E	29_L	0.688	0.51
28_T	67_D	0.687	0.51
37_A	125_L	0.675	0.50
53_Y	61_Y	0.673	0.50
93_T	103_A	0.664	0.49
37_A	123_A	0.660	0.48
18_P	112_F	0.659	0.48
10_R	99_G	0.658	0.48
45_A	56_Q	0.657	0.48
106_L	109_A	0.654	0.48
66_F	122_D	0.648	0.47
33_E	120_E	0.645	0.47
18_P	132_A	0.643	0.47
18_P	130_D	0.636	0.46
54_Y	59_F	0.633	0.46
39_W	117_Y	0.632	0.45
40_F	48_D	0.626	0.45
62_T	97_R	0.625	0.45
65_E	108_R	0.624	0.45
54_Y	78_N	0.622	0.44
58_D	62_T	0.621	0.44
46_V	114_G	0.617	0.44
23_R	130_D	0.611	0.43
68_E	100_Q	0.610	0.43
50_E	108_R	0.601	0.42
30_A	122_D	0.598	0.42
67_D	97_R	0.594	0.42
52_W	136_D	0.589	0.41
20_S	113_A	0.588	0.41
38_A	118_V	0.584	0.41
51_L	109_A	0.583	0.40
73_A	90_T	0.581	0.40
16_L	20_S	0.579	0.40
61_Y	135_L	0.579	0.40
17_D	45_A	0.577	0.40
76_V	88_A	0.571	0.39
52_W	103_A	0.570	0.39
51_L	94_L	0.567	0.39
45_A	61_Y	0.565	0.39
10_R	112_F	0.563	0.38
27_E	36_T	0.562	0.38
28_T	31_A	0.562	0.38
19_G	32_T	0.559	0.38
81_T	92_A	0.559	0.38
23_R	108_R	0.556	0.38
90_T	131_A	0.554	0.38
68_E	98_S	0.553	0.37
87_F	107_E	0.550	0.37
62_T	122_D	0.550	0.37
34_D	100_Q	0.547	0.37
79_I	97_R	0.546	0.37
45_A	99_G	0.546	0.37
111_V	117_Y	0.541	0.36
19_G	111_V	0.540	0.36
9_G	73_A	0.540	0.36
24_T	48_D	0.539	0.36
14_V	118_V	0.537	0.36
45_A	59_F	0.535	0.36
50_E	63_A	0.535	0.36
43_L	78_N	0.534	0.36
11_E	64_A	0.528	0.35
95_S	101_A	0.527	0.35
19_G	128_E	0.527	0.35
34_D	111_V	0.526	0.35
33_E	118_V	0.526	0.35
55_D	88_A	0.526	0.35
102_L	127_R	0.524	0.35
49_A	102_L	0.523	0.35
23_R	37_A	0.522	0.34
124_D	131_A	0.521	0.34
54_Y	61_Y	0.521	0.34
42_G	112_F	0.518	0.34
61_Y	115_E	0.516	0.34
30_A	35_I	0.516	0.34
38_A	80_A	0.512	0.34
69_P	95_S	0.511	0.33
129_H	132_A	0.508	0.33
34_D	131_A	0.506	0.33
32_T	129_H	0.505	0.33
25_E	60_E	0.504	0.33
47_Q	72_V	0.500	0.32

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3htnA	3	0.9856	100	0.228	Contact Map
2h6lA	3	0.9928	100	0.242	Contact Map
3hwuA	3	0.9784	100	0.256	Contact Map
2dt4A	3	0.9928	100	0.274	Contact Map
2hx0A	3	0.9281	100	0.375	Contact Map
2p6yA	3	0.8849	100	0.376	Contact Map
4bt2A	2	0.9424	54.1	0.92	Contact Map
1xv2A	2	0.9353	44	0.924	Contact Map
1hcuA	1	0.5971	34.3	0.929	Contact Map
1nxcA	1	0.5971	11	0.943	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0064 seconds.