Q9HMW4 - HALSA - GREMLIN Contacts

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Q9HMW4 - Oligopeptide binding protein

UniProt:	Q9HMW4	Sequences: MANRDNHARPSRPNTDQSTSEAHSRRRVLKALGATGVAAGVAGCLGGGSDDSAATATSEETSSPDTETLQPENIPRGGTFKVATTSTTNGLNAFRIGDGQTSARVNSVMDAGFSRTGEAYEDILPLWFEDFSVSEPVDQIEITLRDNLEYGNGYGELTADDYLWNLNNLWRPDWTAFTYSHLFNVGADNTPITFEKVDKYTIRETIPEPRPFFPYNEPLGGMYPIPKALAKPYVEAEDADGLEQDEEVMRAAFNGNLGPWDLKRWSQQSVMAFERAEDYYLRQWAKRDDRVPEVMANAPYFDEFHMQYFNKASTAREALKGGEIDRVSIPSTDVPEFRDQGGIELYKNPYRSWSGYLGINHRANGWTQLRNKKVRHAMAHIYHNEFIVENILNGRAGVQNTLHPTWGPYAPENPTTFSGSLDEARRLLKEGTSNDYGYSGDTFVGPDGNQVELTIVYQSGQTDDLRAAYLKKRLGKVGIKLNQETTSWPNLMSNYFKTTETAPGFSGEPGYGDENRQPSDYNRGPQDEAVSAQPWDFMLTLGFDYGPNTPASTITNLFGTEQSFNSYGYAPDRDLVGMRDAAQTAASRDAAKAKITEMLEYLSEERPVIFEYNPYNFYAYNDSVENIPDSPANDYYVEERYSEMYFSDGASGR	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	653 (499)
Sequences:	17496 (13532)
Seq/√Len:	605.8

ECOLI - YEJA OPPA YGIS SAPA MPPA NIKA DDPA DPPA GSIB YBAE SGRR
BACSU - APPA OPPA DPPE YHJP
HALSA - Q9HMW4 Q9HMI3
SULSO - Q97UG7 Q97VF7 Q97VK5 Q97UH5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
263_K	274_E	4.297	1.00
373_K	430_E	3.449	1.00
195_E	203_R	3.306	1.00
197_V	203_R	3.303	1.00
423_E	426_R	3.264	1.00
385_E	389_E	3.164	1.00
198_D	201_T	3.101	1.00
146_D	200_Y	3.080	1.00
452_E	480_K	3.064	1.00
577_G	581_A	2.986	1.00
163_L	167_N	2.890	1.00
585_A	590_A	2.817	1.00
261_D	274_E	2.761	1.00
452_E	482_N	2.696	1.00
163_L	196_K	2.627	1.00
79_T	303_E	2.581	1.00
227_K	231_K	2.581	1.00
367_T	370_R	2.537	1.00
383_H	386_F	2.534	1.00
378_M	474_L	2.521	1.00
569_Y	605_E	2.495	1.00
426_R	430_E	2.474	1.00
454_T	484_E	2.459	1.00
380_H	423_E	2.435	1.00
116_T	122_D	2.361	1.00
574_D	577_G	2.359	1.00
132_S	143_T	2.349	1.00
373_K	376_H	2.332	1.00
195_E	205_T	2.322	1.00
130_D	143_T	2.320	1.00
160_D	196_K	2.295	1.00
454_T	482_N	2.290	1.00
157_L	257_L	2.267	1.00
134_S	138_D	2.249	1.00
113_F	131_F	2.234	1.00
139_Q	203_R	2.218	1.00
116_T	124_L	2.203	1.00
475_G	480_K	2.192	1.00
372_K	376_H	2.184	1.00
154_Y	228_A	2.177	1.00
151_G	276_A	2.173	1.00
373_K	427_L	2.156	1.00
590_A	593_A	2.123	1.00
363_A	501_T	2.123	1.00
139_Q	205_T	2.104	1.00
581_A	594_K	2.099	1.00
149_E	156_E	2.077	1.00
148_L	157_L	2.070	1.00
572_D	605_E	2.065	1.00
587_S	590_A	2.065	1.00
272_A	303_E	2.060	1.00
149_E	278_D	2.041	1.00
572_D	601_Y	2.026	1.00
160_D	227_K	2.017	1.00
79_T	305_H	1.997	1.00
133_V	140_I	1.995	1.00
110_D	126_L	1.958	1.00
593_A	597_E	1.951	1.00
318_A	323_E	1.938	1.00
141_E	203_R	1.935	1.00
143_T	201_T	1.902	1.00
261_D	277_E	1.872	1.00
129_E	146_D	1.867	1.00
192_I	207_P	1.862	1.00
166_L	204_E	1.860	1.00
266_S	269_S	1.849	1.00
471_K	475_G	1.846	1.00
83_A	324_I	1.845	1.00
574_D	597_E	1.803	1.00
81_K	305_H	1.787	1.00
92_N	168_N	1.773	1.00
162_Y	202_I	1.772	1.00
372_K	605_E	1.767	1.00
381_I	477_V	1.766	1.00
582_A	595_I	1.762	1.00
399_Q	613_N	1.761	1.00
158_T	161_D	1.750	1.00
575_L	598_M	1.750	1.00
264_R	272_A	1.736	1.00
160_D	163_L	1.728	1.00
359_I	609_I	1.724	1.00
161_D	227_K	1.724	1.00
78_G	302_D	1.709	1.00
152_N	226_P	1.708	1.00
578_M	597_E	1.708	1.00
129_E	143_T	1.697	1.00
274_E	303_E	1.693	1.00
160_D	199_K	1.689	1.00
582_A	594_K	1.662	1.00
147_N	156_E	1.642	1.00
154_Y	226_P	1.642	1.00
600_E	604_E	1.637	1.00
116_T	120_Y	1.635	1.00
376_H	423_E	1.625	1.00
494_N	499_T	1.613	1.00
263_K	303_E	1.612	1.00
264_R	270_V	1.606	1.00
570_A	576_V	1.592	1.00
573_R	577_G	1.586	1.00
129_E	145_R	1.584	1.00
275_R	302_D	1.583	1.00
493_S	497_K	1.580	1.00
134_S	139_Q	1.579	1.00
270_V	305_H	1.575	1.00
420_S	423_E	1.573	1.00
369_L	453_L	1.549	1.00
597_E	600_E	1.542	1.00
266_S	270_V	1.537	1.00
574_D	601_Y	1.533	1.00
113_F	142_I	1.531	1.00
284_W	299_P	1.530	1.00
425_R	429_K	1.527	1.00
159_A	196_K	1.524	1.00
570_A	573_R	1.514	1.00
309_F	318_A	1.506	1.00
578_M	594_K	1.504	1.00
193_T	205_T	1.500	1.00
594_K	597_E	1.491	1.00
560_T	570_A	1.486	1.00
320_K	336_E	1.463	1.00
359_I	502_A	1.456	1.00
260_W	301_F	1.455	1.00
385_E	398_V	1.449	1.00
382_Y	470_L	1.447	1.00
422_D	425_R	1.442	1.00
131_F	142_I	1.442	1.00
379_A	606_R	1.425	1.00
362_R	568_G	1.422	1.00
487_S	490_N	1.420	1.00
372_K	604_E	1.417	1.00
593_A	596_T	1.412	1.00
429_K	434_N	1.402	1.00
98_D	101_T	1.395	1.00
116_T	119_A	1.385	1.00
450_Q	480_K	1.385	1.00
592_K	596_T	1.384	1.00
156_E	200_Y	1.381	1.00
141_E	201_T	1.379	1.00
560_T	576_V	1.378	1.00
363_A	368_Q	1.377	1.00
581_A	590_A	1.377	1.00
464_D	468_A	1.375	1.00
577_G	580_D	1.374	1.00
585_A	594_K	1.372	1.00
134_S	141_E	1.371	1.00
376_H	606_R	1.370	1.00
335_P	338_R	1.367	1.00
569_Y	572_D	1.366	1.00
342_G	622_D	1.361	1.00
151_G	261_D	1.359	1.00
388_V	398_V	1.356	1.00
433_S	446_P	1.354	1.00
158_T	199_K	1.343	1.00
457_Y	483_Q	1.336	1.00
263_K	272_A	1.332	1.00
405_T	613_N	1.329	1.00
110_D	257_L	1.327	1.00
484_E	494_N	1.319	1.00
81_K	325_D	1.318	1.00
344_E	622_D	1.317	1.00
272_A	305_H	1.315	1.00
83_A	315_A	1.307	1.00
601_Y	605_E	1.298	1.00
77_G	302_D	1.298	1.00
197_V	201_T	1.295	1.00
590_A	594_K	1.291	1.00
110_D	280_Y	1.288	1.00
152_N	228_A	1.285	1.00
226_P	229_L	1.283	1.00
427_L	430_E	1.279	1.00
472_K	476_K	1.272	1.00
455_I	481_L	1.259	1.00
149_E	276_A	1.255	1.00
457_Y	485_T	1.253	1.00
374_V	428_L	1.253	1.00
148_L	257_L	1.246	1.00
469_Y	473_R	1.246	1.00
204_E	213_F	1.243	1.00
163_L	194_F	1.242	1.00
273_F	306_M	1.240	1.00
194_F	202_I	1.231	1.00
143_T	200_Y	1.229	1.00
374_V	431_G	1.229	1.00
473_R	476_K	1.229	1.00
378_M	479_I	1.224	1.00
196_K	199_K	1.214	1.00
208_E	584_T	1.213	1.00
281_L	284_W	1.211	1.00
574_D	578_M	1.209	1.00
151_G	278_D	1.209	1.00
80_F	326_R	1.205	1.00
498_T	568_G	1.201	1.00
162_Y	224_P	1.201	1.00
104_R	273_F	1.193	1.00
125_P	131_F	1.182	1.00
145_R	280_Y	1.182	1.00
471_K	483_Q	1.168	1.00
145_R	148_L	1.165	1.00
81_K	307_Q	1.156	1.00
421_L	425_R	1.156	1.00
369_L	378_M	1.154	1.00
270_V	307_Q	1.150	1.00
325_D	621_N	1.150	1.00
388_V	396_A	1.144	1.00
578_M	601_Y	1.144	1.00
319_L	619_A	1.140	1.00
488_W	492_M	1.140	1.00
318_A	324_I	1.140	1.00
192_I	205_T	1.139	1.00
569_Y	575_L	1.132	1.00
376_H	427_L	1.130	1.00
581_A	585_A	1.126	1.00
426_R	429_K	1.121	1.00
358_G	503_P	1.116	1.00
474_L	481_L	1.115	1.00
589_D	593_A	1.113	1.00
165_N	224_P	1.110	1.00
575_L	602_L	1.108	1.00
589_D	592_K	1.105	1.00
167_N	171_R	1.097	1.00
335_P	339_D	1.096	1.00
381_I	474_L	1.096	1.00
386_F	473_R	1.095	1.00
453_L	481_L	1.093	1.00
325_D	623_S	1.090	1.00
127_W	162_Y	1.082	1.00
363_A	370_R	1.081	1.00
157_L	224_P	1.080	1.00
601_Y	604_E	1.079	1.00
453_L	502_A	1.077	1.00
132_S	141_E	1.077	1.00
261_D	276_A	1.075	1.00
513_D	591_A	1.067	1.00
140_I	213_F	1.064	1.00
159_A	197_V	1.064	1.00
471_K	481_L	1.061	1.00
164_W	227_K	1.060	1.00
581_A	597_E	1.058	1.00
228_A	232_P	1.058	1.00
320_K	340_Q	1.055	1.00
422_D	426_R	1.055	1.00
110_D	279_Y	1.045	1.00
423_E	427_L	1.044	1.00
314_T	318_A	1.041	1.00
44_C	47_G	1.040	1.00
229_L	254_N	1.040	1.00
578_M	598_M	1.038	1.00
421_L	477_V	1.038	1.00
472_K	475_G	1.033	1.00
274_E	277_E	1.030	1.00
569_Y	607_P	1.029	1.00
578_M	581_A	1.026	1.00
129_E	200_Y	1.024	1.00
392_L	612_Y	1.021	1.00
359_I	378_M	1.020	1.00
156_E	199_K	1.018	1.00
470_L	474_L	1.017	1.00
114_S	124_L	1.017	1.00
142_I	204_E	1.008	1.00
151_G	254_N	1.006	1.00
146_D	156_E	1.005	1.00
376_H	604_E	1.004	1.00
575_L	579_R	0.999	1.00
114_S	126_L	0.999	1.00
465_L	468_A	0.999	1.00
317_E	320_K	0.991	1.00
379_A	609_I	0.990	1.00
159_A	202_I	0.986	1.00
143_T	146_D	0.983	1.00
150_Y	161_D	0.981	1.00
143_T	198_D	0.979	1.00
397_G	615_Y	0.978	1.00
80_F	624_V	0.978	1.00
379_A	384_N	0.973	1.00
411_P	596_T	0.968	1.00
387_I	466_R	0.962	1.00
127_W	148_L	0.960	1.00
467_A	483_Q	0.960	1.00
76_R	300_Y	0.952	1.00
324_I	327_V	0.948	1.00
344_E	620_Y	0.948	1.00
140_I	214_P	0.943	1.00
80_F	301_F	0.942	1.00
372_K	606_R	0.941	1.00
347_K	615_Y	0.940	1.00
580_D	584_T	0.939	1.00
37_V	40_G	0.939	1.00
582_A	598_M	0.938	1.00
411_P	600_E	0.936	1.00
451_V	479_I	0.935	1.00
140_I	206_I	0.935	1.00
161_D	164_W	0.932	1.00
392_L	396_A	0.921	1.00
373_K	431_G	0.916	1.00
389_E	394_G	0.915	1.00
196_K	202_I	0.914	1.00
147_N	200_Y	0.912	1.00
44_C	48_G	0.912	1.00
421_L	476_K	0.909	1.00
434_N	446_P	0.909	1.00
388_V	612_Y	0.908	1.00
160_D	164_W	0.907	1.00
163_L	202_I	0.906	1.00
376_H	380_H	0.905	1.00
383_H	473_R	0.904	1.00
490_N	493_S	0.903	1.00
164_W	230_A	0.903	1.00
386_F	390_N	0.903	1.00
588_R	592_K	0.898	1.00
334_V	338_R	0.897	1.00
333_D	336_E	0.896	1.00
575_L	601_Y	0.891	1.00
111_A	126_L	0.890	1.00
141_E	197_V	0.889	1.00
87_T	265_W	0.888	1.00
134_S	137_V	0.884	1.00
335_P	393_N	0.883	1.00
330_P	333_D	0.880	1.00
402_L	610_F	0.880	1.00
167_N	194_F	0.878	1.00
41_V	44_C	0.875	1.00
486_T	494_N	0.875	1.00
456_V	486_T	0.873	1.00
206_I	213_F	0.872	1.00
128_F	142_I	0.872	1.00
127_W	257_L	0.870	1.00
377_A	428_L	0.868	1.00
456_V	494_N	0.868	1.00
434_N	448_G	0.866	1.00
213_F	217_E	0.865	1.00
36_G	39_A	0.865	1.00
108_V	273_F	0.864	1.00
378_M	453_L	0.863	1.00
454_T	501_T	0.863	1.00
346_Y	620_Y	0.863	1.00
397_G	405_T	0.861	1.00
151_G	255_G	0.858	1.00
380_H	417_F	0.857	1.00
316_R	320_K	0.852	1.00
353_W	508_E	0.848	1.00
275_R	283_Q	0.846	1.00
380_H	427_L	0.841	1.00
151_G	262_L	0.837	1.00
275_R	301_F	0.834	1.00
283_Q	299_P	0.832	1.00
275_R	282_R	0.829	1.00
93_A	225_I	0.823	1.00
343_I	619_A	0.823	1.00
581_A	584_T	0.821	1.00
358_G	567_Y	0.820	1.00
113_F	214_P	0.819	1.00
495_Y	503_P	0.818	1.00
107_S	273_F	0.818	1.00
275_R	299_P	0.817	1.00
273_F	304_F	0.816	1.00
78_G	301_F	0.815	1.00
27_R	30_K	0.815	1.00
579_R	598_M	0.814	1.00
384_N	398_V	0.811	1.00
94_F	169_L	0.811	1.00
371_N	433_S	0.810	1.00
74_I	300_Y	0.809	1.00
138_D	205_T	0.807	1.00
355_G	463_D	0.805	1.00
113_F	123_I	0.804	1.00
142_I	214_P	0.802	1.00
363_A	367_T	0.801	1.00
111_A	223_Y	0.799	1.00
319_L	343_I	0.795	1.00
598_M	601_Y	0.794	1.00
362_R	498_T	0.793	1.00
573_R	576_V	0.792	1.00
337_F	343_I	0.792	1.00
457_Y	467_A	0.791	1.00
596_T	600_E	0.787	1.00
113_F	128_F	0.784	1.00
381_I	421_L	0.782	1.00
171_R	174_W	0.781	1.00
190_T	208_E	0.778	1.00
127_W	157_L	0.776	1.00
108_V	255_G	0.773	1.00
108_V	262_L	0.773	1.00
401_T	599_L	0.772	1.00
309_F	324_I	0.771	1.00
460_G	464_D	0.769	1.00
87_T	308_Y	0.765	1.00
317_E	321_G	0.764	1.00
82_V	326_R	0.764	1.00
262_L	271_M	0.762	1.00
338_R	347_K	0.762	1.00
387_I	469_Y	0.761	1.00
357_L	502_A	0.761	1.00
265_W	271_M	0.761	1.00
75_P	78_G	0.760	1.00
490_N	494_N	0.757	1.00
382_Y	387_I	0.753	1.00
411_P	414_P	0.750	1.00
39_A	42_A	0.749	1.00
165_N	225_I	0.747	1.00
159_A	163_L	0.747	1.00
148_L	200_Y	0.747	1.00
167_N	170_W	0.745	1.00
196_K	203_R	0.744	1.00
190_T	210_R	0.744	1.00
94_F	168_N	0.744	1.00
133_V	137_V	0.742	1.00
161_D	165_N	0.741	1.00
109_M	255_G	0.741	1.00
361_H	607_P	0.740	1.00
424_A	477_V	0.739	1.00
340_Q	343_I	0.739	1.00
458_Q	463_D	0.738	1.00
277_E	302_D	0.738	1.00
274_E	302_D	0.736	1.00
357_L	470_L	0.736	1.00
131_F	214_P	0.736	1.00
319_L	327_V	0.735	1.00
142_I	217_E	0.733	1.00
468_A	483_Q	0.732	1.00
382_Y	474_L	0.732	1.00
38_A	41_V	0.732	1.00
132_S	135_E	0.731	1.00
361_H	567_Y	0.730	1.00
37_V	41_V	0.729	1.00
210_R	216_N	0.727	1.00
40_G	43_G	0.725	1.00
138_D	208_E	0.725	1.00
456_V	484_E	0.725	1.00
112_G	128_F	0.724	1.00
33_G	36_G	0.723	1.00
316_R	337_F	0.723	1.00
427_L	431_G	0.723	1.00
315_A	327_V	0.722	1.00
80_F	304_F	0.722	1.00
226_P	254_N	0.721	1.00
87_T	267_Q	0.720	1.00
152_N	254_N	0.717	1.00
107_S	304_F	0.716	1.00
374_V	433_S	0.716	1.00
96_I	105_V	0.715	1.00
419_G	476_K	0.715	1.00
468_A	471_K	0.714	1.00
44_C	50_D	0.713	1.00
380_H	419_G	0.712	1.00
374_V	451_V	0.711	1.00
411_P	599_L	0.711	1.00
342_G	621_N	0.709	1.00
456_V	500_E	0.709	1.00
30_K	33_G	0.707	1.00
78_G	300_Y	0.706	1.00
349_P	615_Y	0.705	1.00
115_R	123_I	0.705	1.00
51_D	54_A	0.705	1.00
228_A	231_K	0.702	1.00
559_G	580_D	0.699	1.00
341_G	345_L	0.699	1.00
148_L	280_Y	0.697	1.00
457_Y	464_D	0.695	1.00
455_I	467_A	0.695	1.00
464_D	485_T	0.695	1.00
597_E	601_Y	0.694	1.00
371_N	431_G	0.693	1.00
569_Y	601_Y	0.687	1.00
44_C	49_S	0.687	1.00
164_W	231_K	0.687	1.00
167_N	190_T	0.686	1.00
428_L	433_S	0.686	1.00
474_L	479_I	0.685	1.00
169_L	221_G	0.685	1.00
261_D	278_D	0.684	1.00
359_I	369_L	0.684	1.00
491_L	503_P	0.683	1.00
136_P	139_Q	0.682	1.00
144_L	157_L	0.682	1.00
150_Y	255_G	0.682	1.00
83_A	309_F	0.680	1.00
194_F	204_E	0.677	1.00
33_G	37_V	0.674	1.00
138_D	192_I	0.674	1.00
607_P	610_F	0.674	1.00
119_A	628_P	0.672	1.00
434_N	447_D	0.672	1.00
138_D	209_P	0.670	1.00
428_L	451_V	0.668	1.00
428_L	431_G	0.667	1.00
157_L	165_N	0.666	1.00
47_G	50_D	0.666	1.00
163_L	195_E	0.665	1.00
104_R	271_M	0.665	1.00
594_K	598_M	0.664	1.00
591_A	595_I	0.663	1.00
474_L	502_A	0.663	1.00
144_L	148_L	0.663	1.00
326_R	624_V	0.661	1.00
260_W	303_E	0.660	1.00
96_I	101_T	0.658	1.00
150_Y	224_P	0.658	1.00
507_G	510_G	0.657	1.00
319_L	621_N	0.656	1.00
150_Y	228_A	0.655	1.00
415_T	418_S	0.655	1.00
77_G	300_Y	0.654	1.00
126_L	280_Y	0.654	1.00
337_F	619_A	0.653	1.00
582_A	591_A	0.652	1.00
144_L	200_Y	0.652	1.00
408_P	588_R	0.649	1.00
455_I	504_G	0.649	1.00
580_D	583_Q	0.648	1.00
229_L	233_Y	0.647	1.00
137_V	586_A	0.646	1.00
486_T	490_N	0.645	1.00
102_S	220_G	0.644	1.00
588_R	591_A	0.644	1.00
466_R	612_Y	0.644	1.00
475_G	479_I	0.643	1.00
621_N	624_V	0.643	1.00
369_L	374_V	0.639	1.00
378_M	609_I	0.639	1.00
309_F	315_A	0.639	1.00
470_L	481_L	0.639	1.00
363_A	369_L	0.638	1.00
620_Y	627_I	0.636	1.00
466_R	470_L	0.636	1.00
110_D	281_L	0.636	1.00
159_A	198_D	0.629	1.00
433_S	451_V	0.628	1.00
91_L	265_W	0.628	1.00
468_A	472_K	0.627	1.00
262_L	273_F	0.626	1.00
158_T	227_K	0.626	1.00
191_P	194_F	0.625	1.00
166_L	217_E	0.624	1.00
407_G	410_A	0.624	1.00
311_K	314_T	0.624	1.00
380_H	418_S	0.623	1.00
307_Q	318_A	0.622	1.00
361_H	370_R	0.621	1.00
211_P	591_A	0.620	1.00
109_M	253_F	0.619	1.00
48_G	51_D	0.619	1.00
260_W	299_P	0.619	1.00
32_L	35_T	0.618	1.00
382_Y	609_I	0.618	1.00
158_T	200_Y	0.617	1.00
382_Y	611_E	0.617	1.00
486_T	491_L	0.617	1.00
262_L	265_W	0.617	1.00
421_L	428_L	0.616	1.00
565_N	568_G	0.615	1.00
432_T	448_G	0.614	1.00
170_W	207_P	0.613	1.00
46_G	49_S	0.613	1.00
385_E	388_V	0.613	1.00
408_P	411_P	0.612	1.00
167_N	196_K	0.611	1.00
458_Q	491_L	0.611	1.00
475_G	481_L	0.609	1.00
572_D	575_L	0.604	1.00
271_M	308_Y	0.604	1.00
150_Y	157_L	0.604	1.00
208_E	580_D	0.603	1.00
368_Q	451_V	0.603	1.00
363_A	499_T	0.603	1.00
356_Y	608_V	0.603	1.00
29_L	32_L	0.602	1.00
387_I	470_L	0.602	1.00
172_P	175_T	0.601	1.00
433_S	448_G	0.599	1.00
576_V	580_D	0.598	1.00
31_A	34_A	0.598	1.00
474_L	477_V	0.597	1.00
131_F	143_T	0.596	1.00
455_I	502_A	0.596	1.00
89_N	98_D	0.595	1.00
28_V	31_A	0.595	1.00
167_N	227_K	0.595	1.00
164_W	228_A	0.594	1.00
157_L	200_Y	0.594	1.00
233_Y	241_G	0.591	1.00
383_H	419_G	0.590	1.00
34_A	38_A	0.590	1.00
357_L	611_E	0.589	1.00
125_P	130_D	0.588	1.00
371_N	374_V	0.588	1.00
359_I	379_A	0.587	1.00
428_L	479_I	0.586	1.00
135_E	139_Q	0.586	1.00
378_M	502_A	0.585	1.00
492_M	495_Y	0.585	1.00
159_A	200_Y	0.585	1.00
433_S	449_N	0.584	1.00
425_R	477_V	0.584	1.00
316_R	333_D	0.583	1.00
115_R	218_P	0.581	1.00
341_G	622_D	0.581	1.00
133_V	214_P	0.581	1.00
362_R	370_R	0.581	1.00
45_L	48_G	0.581	1.00
301_F	624_V	0.579	1.00
448_G	451_V	0.577	1.00
212_F	513_D	0.577	1.00
488_W	505_F	0.577	1.00
322_G	621_N	0.576	1.00
354_S	399_Q	0.575	1.00
282_R	299_P	0.574	1.00
379_A	417_F	0.574	1.00
429_K	433_S	0.574	1.00
234_V	240_D	0.573	1.00
319_L	324_I	0.571	1.00
347_K	617_F	0.570	1.00
49_S	52_S	0.570	1.00
34_A	37_V	0.569	1.00
139_Q	195_E	0.568	1.00
43_G	46_G	0.567	1.00
357_L	455_I	0.567	1.00
281_L	299_P	0.566	1.00
152_N	229_L	0.566	1.00
598_M	602_L	0.566	1.00
371_N	446_P	0.566	1.00
603_S	606_R	0.565	1.00
342_G	345_L	0.565	1.00
44_C	51_D	0.564	1.00
260_W	275_R	0.563	1.00
428_L	432_T	0.563	1.00
515_N	583_Q	0.562	1.00
413_N	596_T	0.561	1.00
312_A	315_A	0.561	1.00
156_E	228_A	0.560	1.00
341_G	344_E	0.559	1.00
167_N	193_T	0.558	1.00
347_K	395_R	0.558	1.00
428_L	477_V	0.558	1.00
586_A	590_A	0.556	1.00
225_I	230_A	0.555	1.00
585_A	591_A	0.555	1.00
318_A	321_G	0.555	1.00
380_H	420_S	0.555	1.00
416_T	603_S	0.555	1.00
357_L	609_I	0.554	1.00
113_F	218_P	0.554	1.00
114_S	281_L	0.554	1.00
567_Y	608_V	0.553	0.99
111_A	142_I	0.553	0.99
50_D	53_A	0.552	0.99
49_S	53_A	0.552	0.99
164_W	168_N	0.552	0.99
253_F	262_L	0.551	0.99
585_A	588_R	0.550	0.99
355_G	466_R	0.549	0.99
334_V	617_F	0.549	0.99
606_R	609_I	0.548	0.99
135_E	205_T	0.548	0.99
414_P	600_E	0.548	0.99
446_P	449_N	0.546	0.99
150_Y	158_T	0.546	0.99
414_P	603_S	0.546	0.99
98_D	488_W	0.546	0.99
373_K	426_R	0.544	0.99
282_R	300_Y	0.544	0.99
313_S	333_D	0.544	0.99
388_V	392_L	0.543	0.99
233_Y	252_A	0.543	0.99
74_I	78_G	0.542	0.99
154_Y	161_D	0.542	0.99
493_S	496_F	0.541	0.99
408_P	592_K	0.540	0.99
604_E	607_P	0.540	0.99
183_F	192_I	0.539	0.99
48_G	54_A	0.539	0.99
371_N	430_E	0.539	0.99
374_V	378_M	0.538	0.99
355_G	614_P	0.538	0.99
77_G	303_E	0.538	0.99
133_V	139_Q	0.538	0.99
307_Q	323_E	0.536	0.99
387_I	611_E	0.534	0.99
150_Y	165_N	0.534	0.99
168_N	230_A	0.534	0.99
32_L	36_G	0.534	0.99
176_A	179_Y	0.534	0.99
84_T	88_T	0.534	0.99
113_F	217_E	0.533	0.99
584_T	594_K	0.533	0.99
391_I	469_Y	0.533	0.99
35_T	38_A	0.533	0.99
386_F	469_Y	0.533	0.99
409_Y	592_K	0.532	0.99
36_G	40_G	0.532	0.99
624_V	627_I	0.531	0.99
481_L	502_A	0.530	0.99
371_N	432_T	0.529	0.99
133_V	138_D	0.529	0.99
111_A	257_L	0.528	0.99
196_K	201_T	0.528	0.99
108_V	253_F	0.528	0.99
433_S	447_D	0.528	0.99
30_K	37_V	0.527	0.99
81_K	324_I	0.527	0.99
154_Y	227_K	0.525	0.99
575_L	578_M	0.524	0.99
459_S	485_T	0.523	0.99
76_R	302_D	0.522	0.99
84_T	306_M	0.521	0.99
463_D	504_G	0.521	0.99
107_S	306_M	0.520	0.99
420_S	426_R	0.519	0.99
488_W	491_L	0.519	0.99
150_Y	154_Y	0.518	0.99
151_G	257_L	0.517	0.99
368_Q	501_T	0.517	0.99
515_N	595_I	0.515	0.99
189_N	192_I	0.514	0.99
381_I	419_G	0.513	0.99
79_T	272_A	0.513	0.99
492_M	496_F	0.513	0.99
451_V	477_V	0.513	0.99
385_E	418_S	0.513	0.99
43_G	47_G	0.513	0.99
572_D	577_G	0.511	0.99
251_A	267_Q	0.510	0.99
280_Y	284_W	0.510	0.99
105_V	108_V	0.510	0.99
313_S	317_E	0.509	0.99
345_L	619_A	0.509	0.99
90_G	95_R	0.508	0.99
340_Q	622_D	0.507	0.99
334_V	395_R	0.507	0.99
105_V	109_M	0.507	0.99
142_I	202_I	0.506	0.99
447_D	450_Q	0.504	0.99
413_N	416_T	0.504	0.99
458_Q	461_Q	0.504	0.99
164_W	225_I	0.504	0.99
112_G	162_Y	0.503	0.99
463_D	506_S	0.503	0.99
265_W	308_Y	0.503	0.99
29_L	33_G	0.502	0.99
469_Y	472_K	0.502	0.99
433_S	450_Q	0.502	0.99
355_G	611_E	0.502	0.99
360_N	501_T	0.502	0.99
377_A	427_L	0.501	0.99
128_F	131_F	0.501	0.99
329_I	334_V	0.501	0.99
283_Q	300_Y	0.500	0.99
125_P	128_F	0.500	0.99
413_N	600_E	0.500	0.99

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1xocA	2	0.7642	100	0.27	Contact Map
4qflA	1	0.7473	100	0.275	Contact Map
3drfA	1	0.7626	100	0.285	Contact Map
4wedA	1	0.7228	100	0.285	Contact Map
4fajA	1	0.7443	100	0.291	Contact Map
4oevA	1	0.7519	100	0.291	Contact Map
3zs6A	1	0.7473	100	0.296	Contact Map
2grvA	1	0.7458	100	0.298	Contact Map
4tozA	1	0.7642	100	0.301	Contact Map
1jetA	1	0.7611	100	0.306	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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