HELS - HALSA - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

HELS - ATP-dependent DNA helicase Hel308

UniProt:	Q9HMV6	Sequences: MRVADVPGLPGGVADHFEGEGVEELYPPQAEAVERGVTEGANLVASVPTASGKTLIAQLAMLSAIAEGGDSPTFSGDGTALYIVPLRALAGEKAQEFEAFERFGLSVGVSTGNYERDGARLADNDIVVATSEKVDSLVRNGAGWIDDLSCVVADEVHLVDDDHRGPTLEVTLAKLRQQVADLQVVALSATVGNAGELAAWLDAELVDSDWRPIELRTGVHYGQSLHYDDGTQAELSVGSGSQTAAVVADTLADDGSTLVFVNSRRNAEASARRLADVTGNALSSAERERLADIAAEIRGVSDTETSDELADAVASGAAFHHAGLAREHRELVEEAFRDRLVKAVSATPTLAAGVNTPARRVVVRDWQRYDGTAGGMQPLDVLEVHQMFGRAGRPGLDPYGEAVLLANSHDELEELFDRYVYADPEPVRSKLAAEPALRTHVLAAIATGFTTTEDGLHEFLGGTLYATQTDDTGRLRSVTGDVLRYLDRNGFVERDGAALRATATGQLVSRLYVDPMSAATIIDGLRDAARDATETDDEGAFRPASELGDDAALPADASVEPTPLGLYHLVSRTPDMYELYLRSGDREQYTEVAYEHEDELLGATPREEQAEFEDWLSALKTARLMADWASELDEERIAERYDVGPGDIRGKVETAEWLLNAAERLAGELDVECGPAVREARKRVQYGVREELLGLAGVRNVGRKRARRLYNAGVESRADLRNADKGVVLGAVRGRAATAERILETVGHPDPGMDGVAADTDAAPESGGEAGGDEGQASLGDFS	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	783 (624)
Sequences:	3671 (2338)
Seq/√Len:	93.6

ECOLI - YFJK DEAD RECQ
BACSU - YPRA
HALSA - HELS Q9HN80 Q9HNB2
SULSO - HELS Q981C8 Q980C0 HELX

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
156_V	186_A	6.838	1.00
151_V	175_L	4.314	1.00
291_A	314_A	4.239	1.00
78_G	149_S	4.224	1.00
318_A	341_V	3.735	1.00
239_S	242_Q	3.462	1.00
41_A	204_E	3.248	1.00
259_V	343_A	3.199	1.00
240_G	247_V	3.184	1.00
45_A	56_I	3.139	1.00
483_L	499_L	3.066	1.00
106_S	123_D	3.038	1.00
93_K	96_E	2.992	1.00
445_I	492_V	2.939	1.00
502_T	505_G	2.926	1.00
289_R	338_D	2.915	1.00
501_A	505_G	2.814	1.00
239_S	243_T	2.811	1.00
63_S	67_E	2.777	1.00
239_S	246_V	2.761	1.00
625_M	655_A	2.657	1.00
153_A	172_L	2.620	1.00
239_S	244_A	2.607	1.00
627_D	641_Y	2.559	1.00
106_S	125_D	2.540	1.00
469_T	474_R	2.537	1.00
240_G	243_T	2.527	1.00
412_L	415_L	2.434	1.00
292_D	296_E	2.432	1.00
60_A	64_A	2.363	1.00
452_T	455_G	2.345	1.00
40_G	63_S	2.336	1.00
135_D	139_R	2.328	1.00
190_T	386_Q	2.300	1.00
334_E	338_D	2.295	1.00
217_T	384_V	2.294	1.00
517_S	525_L	2.283	1.00
172_L	201_L	2.277	1.00
240_G	244_A	2.270	1.00
157_H	386_Q	2.242	1.00
476_R	482_V	2.227	1.00
216_R	399_Y	2.208	1.00
59_L	62_L	2.205	1.00
507_L	510_R	2.164	1.00
620_K	623_R	2.142	1.00
155_E	390_R	2.133	1.00
272_R	308_E	2.120	1.00
353_G	390_R	2.088	1.00
289_R	292_D	2.078	1.00
515_P	518_A	2.071	1.00
564_L	568_H	2.053	1.00
359_R	397_D	2.047	1.00
307_D	311_D	2.020	1.00
169_E	200_W	1.997	1.00
320_H	349_T	1.972	1.00
242_Q	246_V	1.970	1.00
505_G	508_V	1.933	1.00
288_E	292_D	1.929	1.00
566_L	573_T	1.889	1.00
246_V	249_D	1.888	1.00
476_R	480_G	1.871	1.00
94_A	98_E	1.843	1.00
132_E	349_T	1.842	1.00
242_Q	247_V	1.839	1.00
484_R	488_R	1.823	1.00
464_L	468_Q	1.810	1.00
478_V	482_V	1.802	1.00
483_L	490_G	1.793	1.00
702_G	705_R	1.786	1.00
508_V	518_A	1.785	1.00
525_L	528_A	1.778	1.00
290_L	293_I	1.775	1.00
30_A	34_E	1.774	1.00
386_Q	390_R	1.764	1.00
49_T	389_G	1.756	1.00
221_Y	225_L	1.753	1.00
83_I	129_A	1.753	1.00
659_L	684_V	1.752	1.00
390_R	393_R	1.750	1.00
243_T	247_V	1.745	1.00
165_G	169_E	1.743	1.00
61_M	80_A	1.742	1.00
504_T	508_V	1.740	1.00
298_R	302_D	1.736	1.00
286_E	342_K	1.729	1.00
49_T	155_E	1.723	1.00
59_L	64_A	1.711	1.00
240_G	246_V	1.704	1.00
242_Q	245_A	1.696	1.00
560_E	564_L	1.678	1.00
49_T	89_L	1.676	1.00
566_L	569_L	1.664	1.00
320_H	333_E	1.642	1.00
517_S	520_T	1.640	1.00
218_G	401_E	1.602	1.00
600_L	605_P	1.600	1.00
88_A	132_E	1.599	1.00
505_G	513_V	1.596	1.00
347_T	390_R	1.596	1.00
475_L	483_L	1.596	1.00
479_T	483_L	1.595	1.00
627_D	632_L	1.588	1.00
485_Y	489_N	1.581	1.00
332_V	341_V	1.565	1.00
310_A	314_A	1.564	1.00
301_S	304_E	1.562	1.00
244_A	248_A	1.548	1.00
701_V	706_A	1.548	1.00
211_R	215_L	1.544	1.00
289_R	293_I	1.540	1.00
597_E	600_L	1.538	1.00
485_Y	488_R	1.538	1.00
483_L	494_R	1.534	1.00
365_D	371_G	1.529	1.00
61_M	65_I	1.519	1.00
367_Q	376_M	1.511	1.00
289_R	296_E	1.509	1.00
295_A	310_A	1.509	1.00
303_T	306_S	1.492	1.00
505_G	515_P	1.486	1.00
221_Y	224_S	1.483	1.00
619_L	622_A	1.481	1.00
331_L	335_A	1.471	1.00
239_S	249_D	1.468	1.00
293_I	296_E	1.467	1.00
524_G	528_A	1.461	1.00
436_A	440_H	1.456	1.00
504_T	518_A	1.455	1.00
65_I	105_L	1.451	1.00
361_V	364_R	1.451	1.00
701_V	709_L	1.451	1.00
291_A	295_A	1.451	1.00
505_G	518_A	1.447	1.00
86_L	352_A	1.441	1.00
705_R	710_Y	1.431	0.99
491_F	494_R	1.423	0.99
511_L	515_P	1.416	0.99
295_A	298_R	1.415	0.99
504_T	507_L	1.405	0.99
155_E	353_G	1.405	0.99
412_L	416_F	1.403	0.99
164_R	349_T	1.403	0.99
44_V	186_A	1.399	0.99
703_R	707_R	1.396	0.99
475_L	478_V	1.391	0.99
93_K	97_F	1.391	0.99
263_S	266_N	1.387	0.99
510_R	514_D	1.382	0.99
508_V	525_L	1.382	0.99
659_L	680_A	1.381	0.99
499_L	505_G	1.373	0.99
522_I	528_A	1.372	0.99
384_V	402_A	1.369	0.99
54_T	97_F	1.366	0.99
582_R	585_D	1.364	0.99
480_G	483_L	1.362	0.99
459_F	462_G	1.357	0.99
429_S	463_T	1.355	0.99
241_S	246_V	1.353	0.99
590_T	600_L	1.353	0.99
479_T	487_D	1.353	0.99
475_L	482_V	1.351	0.99
596_H	600_L	1.350	0.99
302_D	305_T	1.349	0.99
222_G	225_L	1.349	0.99
502_T	509_S	1.346	0.99
87_R	113_N	1.345	0.99
481_D	484_R	1.344	0.99
193_N	196_E	1.338	0.99
333_E	349_T	1.328	0.99
502_T	507_L	1.324	0.99
388_F	402_A	1.323	0.99
591_E	594_Y	1.322	0.99
84_V	90_A	1.319	0.99
506_Q	510_R	1.319	0.99
490_G	493_E	1.317	0.99
484_R	487_D	1.317	0.99
157_H	321_H	1.315	0.99
264_R	323_G	1.310	0.99
705_R	713_G	1.306	0.99
567_Y	571_S	1.303	0.99
454_D	458_E	1.301	0.99
477_S	481_D	1.301	0.99
617_S	620_K	1.301	0.99
354_V	404_L	1.299	0.99
511_L	518_A	1.297	0.99
453_E	480_G	1.284	0.99
60_A	65_I	1.283	0.99
294_A	297_I	1.279	0.99
347_T	392_G	1.278	0.99
501_A	512_Y	1.273	0.99
565_G	568_H	1.269	0.99
242_Q	250_T	1.266	0.99
25_L	33_V	1.264	0.99
91_G	94_A	1.257	0.99
108_G	124_N	1.255	0.99
291_A	294_A	1.249	0.99
451_T	455_G	1.247	0.99
484_R	497_A	1.245	0.99
583_S	586_R	1.245	0.99
490_G	494_R	1.245	0.99
431_L	440_H	1.243	0.99
469_T	489_N	1.242	0.99
501_A	506_Q	1.240	0.99
112_G	130_T	1.239	0.99
94_A	109_V	1.234	0.98
249_D	253_D	1.233	0.98
312_A	319_F	1.233	0.98
514_D	518_A	1.231	0.98
502_T	506_Q	1.229	0.98
370_D	375_G	1.224	0.98
63_S	66_A	1.223	0.98
97_F	126_I	1.223	0.98
508_V	511_L	1.223	0.98
505_G	509_S	1.214	0.98
482_V	485_Y	1.212	0.98
291_A	296_E	1.208	0.98
507_L	511_L	1.204	0.98
49_T	392_G	1.202	0.98
58_Q	387_M	1.202	0.98
284_S	287_R	1.201	0.98
695_L	698_V	1.199	0.98
667_G	674_G	1.196	0.98
217_T	385_H	1.194	0.98
501_A	507_L	1.190	0.98
45_A	187_L	1.190	0.98
494_R	498_A	1.189	0.98
320_H	355_N	1.187	0.98
709_L	713_G	1.183	0.98
523_D	527_D	1.181	0.98
515_P	519_A	1.179	0.98
428_R	468_Q	1.177	0.98
83_I	134_V	1.177	0.98
487_D	493_E	1.176	0.98
132_E	164_R	1.173	0.98
129_A	134_V	1.172	0.98
196_E	468_Q	1.171	0.98
57_A	187_L	1.168	0.98
389_G	400_G	1.166	0.98
501_A	504_T	1.165	0.98
24_E	30_A	1.163	0.98
88_A	350_L	1.160	0.98
442_L	446_A	1.159	0.98
164_R	355_N	1.154	0.98
513_V	517_S	1.151	0.98
274_L	345_S	1.148	0.98
487_D	490_G	1.147	0.98
318_A	335_A	1.146	0.98
60_A	63_S	1.146	0.98
482_V	486_L	1.144	0.97
153_A	168_L	1.144	0.97
299_G	304_E	1.143	0.97
505_G	511_L	1.143	0.97
370_D	377_Q	1.141	0.97
477_S	482_V	1.135	0.97
491_F	518_A	1.135	0.97
164_R	169_E	1.132	0.97
330_E	334_E	1.130	0.97
483_L	489_N	1.130	0.97
270_S	345_S	1.129	0.97
81_L	127_V	1.127	0.97
155_E	386_Q	1.126	0.97
378_P	410_D	1.126	0.97
267_A	321_H	1.126	0.97
371_G	375_G	1.125	0.97
460_L	465_Y	1.115	0.97
247_V	360_R	1.112	0.97
590_T	604_T	1.111	0.97
613_E	616_L	1.110	0.97
688_V	693_L	1.110	0.97
707_R	710_Y	1.109	0.97
309_L	319_F	1.103	0.97
577_Y	594_Y	1.103	0.97
301_S	306_S	1.100	0.97
484_R	490_G	1.100	0.97
61_M	64_A	1.098	0.97
273_R	277_V	1.098	0.97
510_R	515_P	1.096	0.97
244_A	249_D	1.093	0.97
264_R	322_A	1.090	0.97
47_V	51_S	1.087	0.97
508_V	521_I	1.085	0.97
512_Y	517_S	1.085	0.97
278_T	287_R	1.084	0.97
150_C	183_Q	1.082	0.96
241_S	248_A	1.081	0.96
525_L	529_A	1.079	0.96
247_V	250_T	1.076	0.96
86_L	132_E	1.075	0.96
360_R	403_V	1.071	0.96
597_E	601_L	1.070	0.96
260_F	387_M	1.069	0.96
49_T	357_P	1.066	0.96
239_S	248_A	1.066	0.96
463_T	466_A	1.065	0.96
508_V	513_V	1.065	0.96
674_G	677_V	1.063	0.96
164_R	333_E	1.062	0.96
353_G	393_R	1.059	0.96
33_V	59_L	1.056	0.96
384_V	388_F	1.054	0.96
459_F	463_T	1.053	0.96
309_L	332_V	1.049	0.96
593_A	596_H	1.047	0.96
287_R	290_L	1.042	0.96
285_A	292_D	1.042	0.96
320_H	392_G	1.037	0.96
487_D	494_R	1.037	0.96
291_A	297_I	1.035	0.95
582_R	590_T	1.034	0.95
511_L	519_A	1.034	0.95
579_L	582_R	1.034	0.95
516_M	520_T	1.032	0.95
188_S	191_V	1.028	0.95
510_R	518_A	1.027	0.95
164_R	320_H	1.027	0.95
157_H	323_G	1.027	0.95
354_V	358_A	1.027	0.95
189_A	393_R	1.026	0.95
37_V	63_S	1.022	0.95
366_W	369_Y	1.017	0.95
659_L	681_R	1.017	0.95
458_E	462_G	1.013	0.95
630_S	689_R	1.012	0.95
255_G	359_R	1.009	0.95
302_D	306_S	1.009	0.95
115_E	118_G	1.008	0.95
299_G	302_D	1.008	0.95
518_A	522_I	1.007	0.95
413_E	416_F	1.006	0.95
489_N	492_V	1.006	0.95
645_P	649_R	1.003	0.95
560_E	575_D	1.000	0.95
212_P	215_L	0.999	0.94
499_L	504_T	0.998	0.94
397_D	400_G	0.998	0.94
270_S	364_R	0.992	0.94
683_R	690_E	0.992	0.94
62_L	66_A	0.990	0.94
495_D	498_A	0.987	0.94
266_N	270_S	0.987	0.94
247_V	255_G	0.986	0.94
49_T	53_K	0.986	0.94
297_I	306_S	0.985	0.94
243_T	248_A	0.984	0.94
176_R	202_D	0.981	0.94
663_E	678_R	0.978	0.94
222_G	226_H	0.977	0.94
492_V	499_L	0.977	0.94
242_Q	249_D	0.975	0.94
511_L	514_D	0.974	0.94
583_S	589_Y	0.971	0.94
514_D	521_I	0.969	0.94
58_Q	96_E	0.969	0.94
507_L	517_S	0.969	0.94
48_P	392_G	0.967	0.93
707_R	713_G	0.965	0.93
504_T	522_I	0.964	0.93
30_A	33_V	0.963	0.93
441_V	450_T	0.963	0.93
526_R	529_A	0.961	0.93
300_V	303_T	0.960	0.93
246_V	254_D	0.960	0.93
80_A	126_I	0.958	0.93
609_Q	613_E	0.957	0.93
483_L	487_D	0.957	0.93
258_L	274_L	0.956	0.93
461_G	465_Y	0.955	0.93
478_V	483_L	0.954	0.93
503_A	506_Q	0.954	0.93
84_V	344_V	0.954	0.93
500_R	505_G	0.951	0.93
586_R	590_T	0.950	0.93
463_T	467_T	0.950	0.93
189_A	392_G	0.950	0.93
359_R	364_R	0.950	0.93
505_G	521_I	0.946	0.93
195_G	199_A	0.945	0.93
58_Q	97_F	0.941	0.93
691_E	710_Y	0.940	0.92
258_L	346_A	0.940	0.92
508_V	515_P	0.938	0.92
608_E	611_E	0.938	0.92
710_Y	713_G	0.936	0.92
502_T	517_S	0.927	0.92
151_V	172_L	0.925	0.92
257_T	362_V	0.925	0.92
501_A	510_R	0.923	0.92
83_I	482_V	0.922	0.92
610_A	620_K	0.922	0.92
706_A	709_L	0.922	0.92
573_T	582_R	0.922	0.92
708_R	711_N	0.921	0.92
132_E	350_L	0.920	0.92
88_A	349_T	0.915	0.91
320_H	350_L	0.915	0.91
357_P	392_G	0.915	0.91
486_L	490_G	0.912	0.91
582_R	592_V	0.912	0.91
509_S	517_S	0.907	0.91
520_T	527_D	0.907	0.91
81_L	148_L	0.907	0.91
299_G	303_T	0.906	0.91
333_E	392_G	0.905	0.91
292_D	295_A	0.904	0.91
211_R	214_E	0.903	0.91
576_M	579_L	0.903	0.91
483_L	486_L	0.902	0.91
518_A	523_D	0.902	0.91
561_P	585_D	0.901	0.91
59_L	63_S	0.900	0.91
479_T	482_V	0.897	0.91
625_M	684_V	0.896	0.91
189_A	192_G	0.896	0.91
189_A	389_G	0.895	0.91
298_R	301_S	0.889	0.90
591_E	600_L	0.887	0.90
123_D	144_W	0.887	0.90
90_A	109_V	0.886	0.90
224_S	229_D	0.885	0.90
54_T	58_Q	0.884	0.90
117_D	124_N	0.883	0.90
675_P	678_R	0.883	0.90
296_E	300_V	0.883	0.90
510_R	521_I	0.882	0.90
519_A	523_D	0.881	0.90
493_E	500_R	0.878	0.90
598_D	604_T	0.878	0.90
611_E	615_W	0.878	0.90
256_S	262_N	0.878	0.90
565_G	569_L	0.877	0.90
674_G	681_R	0.872	0.89
329_R	333_E	0.869	0.89
439_T	443_A	0.867	0.89
589_Y	599_E	0.865	0.89
28_P	47_V	0.865	0.89
349_T	355_N	0.862	0.89
49_T	54_T	0.859	0.89
392_G	400_G	0.857	0.89
475_L	479_T	0.857	0.89
389_G	392_G	0.855	0.88
135_D	394_P	0.854	0.88
609_Q	612_F	0.854	0.88
702_G	707_R	0.853	0.88
80_A	152_V	0.853	0.88
49_T	390_R	0.852	0.88
500_R	506_Q	0.850	0.88
347_T	355_N	0.846	0.88
476_R	492_V	0.846	0.88
290_L	300_V	0.845	0.88
507_L	512_Y	0.844	0.88
298_R	314_A	0.844	0.88
212_P	391_A	0.841	0.88
323_G	386_Q	0.841	0.88
586_R	589_Y	0.837	0.87
102_R	105_L	0.837	0.87
592_V	596_H	0.836	0.87
291_A	299_G	0.836	0.87
481_D	487_D	0.834	0.87
662_A	677_V	0.833	0.87
86_L	382_L	0.832	0.87
346_A	356_T	0.830	0.87
27_P	31_E	0.829	0.87
503_A	523_D	0.829	0.87
294_A	310_A	0.828	0.87
480_G	487_D	0.826	0.87
92_E	350_L	0.825	0.87
225_L	228_D	0.824	0.87
504_T	511_L	0.823	0.86
592_V	600_L	0.823	0.86
165_G	320_H	0.821	0.86
616_L	623_R	0.819	0.86
274_L	343_A	0.819	0.86
647_D	654_T	0.818	0.86
157_H	190_T	0.817	0.86
589_Y	600_L	0.816	0.86
521_I	529_A	0.815	0.86
333_E	350_L	0.815	0.86
301_S	305_T	0.814	0.86
490_G	501_A	0.813	0.86
333_E	357_P	0.813	0.86
601_L	605_P	0.813	0.86
40_G	183_Q	0.813	0.86
524_G	527_D	0.813	0.86
464_L	467_T	0.812	0.86
450_T	456_L	0.811	0.86
708_R	713_G	0.809	0.86
92_E	164_R	0.808	0.85
157_H	352_A	0.807	0.85
505_G	512_Y	0.805	0.85
378_P	381_V	0.804	0.85
300_V	304_E	0.801	0.85
271_A	317_A	0.800	0.85
656_E	685_Q	0.800	0.85
617_S	623_R	0.798	0.85
349_T	393_R	0.797	0.85
321_H	392_G	0.797	0.85
513_V	521_I	0.796	0.85
484_R	494_R	0.796	0.85
261_V	267_A	0.796	0.85
487_D	492_V	0.794	0.84
704_K	710_Y	0.794	0.84
488_R	492_V	0.793	0.84
587_E	594_Y	0.792	0.84
160_D	380_D	0.791	0.84
95_Q	330_E	0.791	0.84
696_A	706_A	0.790	0.84
600_L	604_T	0.785	0.84
478_V	481_D	0.783	0.84
49_T	92_E	0.783	0.84
494_R	497_A	0.781	0.83
666_A	673_C	0.780	0.83
289_R	294_A	0.780	0.83
244_A	250_T	0.777	0.83
674_G	678_R	0.775	0.83
522_I	529_A	0.771	0.83
575_D	582_R	0.770	0.83
329_R	350_L	0.768	0.82
688_V	697_G	0.767	0.82
463_T	468_Q	0.767	0.82
689_R	697_G	0.766	0.82
516_M	521_I	0.764	0.82
581_L	588_Q	0.764	0.82
588_Q	591_E	0.763	0.82
288_E	291_A	0.763	0.82
285_A	289_R	0.761	0.82
624_L	648_I	0.759	0.82
506_Q	514_D	0.758	0.82
290_L	294_A	0.757	0.82
83_I	151_V	0.756	0.81
499_L	514_D	0.754	0.81
239_S	251_L	0.754	0.81
564_L	571_S	0.751	0.81
87_R	320_H	0.750	0.81
333_E	355_N	0.750	0.81
358_A	361_V	0.750	0.81
504_T	514_D	0.749	0.81
505_G	510_R	0.749	0.81
508_V	529_A	0.748	0.81
580_Y	583_S	0.744	0.80
193_N	200_W	0.744	0.80
504_T	512_Y	0.743	0.80
316_G	320_H	0.742	0.80
88_A	351_A	0.742	0.80
584_G	588_Q	0.741	0.80
49_T	324_L	0.740	0.80
600_L	603_A	0.740	0.80
676_A	679_E	0.739	0.80
677_V	680_A	0.739	0.80
569_L	572_R	0.739	0.80
601_L	604_T	0.739	0.80
650_G	654_T	0.739	0.80
566_L	571_S	0.738	0.80
704_K	708_R	0.738	0.80
694_G	697_G	0.737	0.80
164_R	350_L	0.736	0.80
624_L	641_Y	0.736	0.80
425_E	428_R	0.735	0.80
517_S	573_T	0.732	0.79
509_S	512_Y	0.732	0.79
240_G	250_T	0.732	0.79
590_T	597_E	0.730	0.79
566_L	570_V	0.730	0.79
479_T	486_L	0.729	0.79
247_V	251_L	0.729	0.79
89_L	155_E	0.728	0.79
489_N	515_P	0.727	0.79
159_V	460_L	0.727	0.79
507_L	513_V	0.725	0.79
308_E	312_A	0.725	0.79
560_E	566_L	0.724	0.79
582_R	588_Q	0.723	0.78
89_L	353_G	0.723	0.78
578_E	595_E	0.722	0.78
239_S	247_V	0.722	0.78
191_V	425_E	0.722	0.78
159_V	186_A	0.721	0.78
474_R	478_V	0.721	0.78
502_T	512_Y	0.721	0.78
272_R	311_D	0.721	0.78
628_W	631_E	0.720	0.78
50_A	322_A	0.720	0.78
489_N	496_G	0.720	0.78
347_T	353_G	0.719	0.78
351_A	357_P	0.719	0.78
92_E	348_P	0.718	0.78
49_T	351_A	0.718	0.78
48_P	350_L	0.714	0.78
88_A	92_E	0.713	0.78
87_R	349_T	0.713	0.78
57_A	152_V	0.713	0.78
605_P	610_A	0.713	0.78
508_V	512_Y	0.712	0.77
241_S	247_V	0.712	0.77
599_E	605_P	0.711	0.77
492_V	496_G	0.711	0.77
223_Q	227_Y	0.711	0.77
243_T	249_D	0.711	0.77
189_A	386_Q	0.709	0.77
88_A	355_N	0.706	0.77
591_E	595_E	0.704	0.77
321_H	386_Q	0.704	0.77
483_L	493_E	0.703	0.77
322_A	357_P	0.702	0.76
568_H	572_R	0.701	0.76
246_V	250_T	0.701	0.76
521_I	662_A	0.700	0.76
610_A	621_T	0.700	0.76
367_Q	378_P	0.700	0.76
569_L	573_T	0.699	0.76
304_E	313_V	0.698	0.76
93_K	400_G	0.698	0.76
648_I	654_T	0.698	0.76
134_V	175_L	0.697	0.76
307_D	310_A	0.695	0.76
245_A	249_D	0.693	0.75
510_R	523_D	0.693	0.75
507_L	522_I	0.692	0.75
517_S	658_L	0.691	0.75
294_A	314_A	0.690	0.75
594_Y	601_L	0.690	0.75
501_A	508_V	0.689	0.75
199_A	467_T	0.687	0.75
469_T	476_R	0.686	0.75
135_D	170_V	0.685	0.75
92_E	353_G	0.684	0.75
92_E	355_N	0.683	0.74
58_Q	93_K	0.683	0.74
347_T	357_P	0.682	0.74
267_A	271_A	0.681	0.74
100_F	126_I	0.679	0.74
521_I	524_G	0.678	0.74
576_M	580_Y	0.677	0.74
459_F	468_Q	0.677	0.74
311_D	314_A	0.676	0.74
505_G	517_S	0.676	0.74
92_E	389_G	0.674	0.73
592_V	595_E	0.673	0.73
244_A	247_V	0.672	0.73
296_E	302_D	0.672	0.73
702_G	708_R	0.669	0.73
296_E	303_T	0.669	0.73
513_V	525_L	0.668	0.73
309_L	312_A	0.667	0.73
296_E	299_G	0.666	0.73
199_A	259_V	0.665	0.72
441_V	456_L	0.665	0.72
354_V	396_L	0.663	0.72
626_A	630_S	0.663	0.72
692_L	707_R	0.663	0.72
576_M	582_R	0.663	0.72
349_T	354_V	0.663	0.72
201_L	215_L	0.659	0.72
243_T	246_V	0.659	0.72
87_R	392_G	0.658	0.72
177_Q	462_G	0.658	0.72
135_D	167_T	0.657	0.72
569_L	585_D	0.656	0.71
224_S	227_Y	0.655	0.71
508_V	517_S	0.655	0.71
132_E	333_E	0.654	0.71
598_D	602_G	0.652	0.71
247_V	253_D	0.650	0.71
486_L	491_F	0.650	0.71
127_V	131_S	0.650	0.71
300_V	305_T	0.650	0.71
585_D	592_V	0.649	0.71
353_G	386_Q	0.648	0.71
695_L	700_N	0.646	0.70
164_R	357_P	0.645	0.70
615_W	621_T	0.645	0.70
489_N	493_E	0.644	0.70
291_A	300_V	0.643	0.70
681_R	685_Q	0.643	0.70
615_W	618_A	0.643	0.70
132_E	391_A	0.643	0.70
509_S	522_I	0.641	0.70
155_E	190_T	0.639	0.69
350_L	355_N	0.639	0.69
680_A	687_G	0.638	0.69
518_A	525_L	0.636	0.69
59_L	65_I	0.636	0.69
561_P	683_R	0.635	0.69
357_P	389_G	0.635	0.69
520_T	526_R	0.635	0.69
455_G	463_T	0.634	0.69
248_A	252_A	0.634	0.69
566_L	576_M	0.634	0.69
271_A	324_L	0.633	0.69
265_R	268_E	0.633	0.69
502_T	523_D	0.632	0.69
475_L	494_R	0.631	0.69
288_E	299_G	0.631	0.69
577_Y	580_Y	0.629	0.68
169_E	429_S	0.628	0.68
589_Y	593_A	0.628	0.68
105_L	125_D	0.627	0.68
256_S	261_V	0.627	0.68
49_T	386_Q	0.627	0.68
692_L	710_Y	0.627	0.68
241_S	244_A	0.626	0.68
499_L	502_T	0.625	0.68
164_R	392_G	0.625	0.68
457_H	465_Y	0.624	0.68
29_Q	52_G	0.624	0.68
132_E	320_H	0.624	0.68
250_T	360_R	0.623	0.68
287_R	296_E	0.623	0.68
92_E	349_T	0.621	0.67
465_Y	468_Q	0.618	0.67
520_T	524_G	0.618	0.67
206_V	211_R	0.617	0.67
565_G	573_T	0.615	0.67
687_G	692_L	0.615	0.67
134_V	139_R	0.614	0.66
51_S	212_P	0.614	0.66
657_W	661_A	0.614	0.66
524_G	529_A	0.614	0.66
294_A	301_S	0.612	0.66
648_I	657_W	0.611	0.66
288_E	293_I	0.610	0.66
499_L	508_V	0.610	0.66
502_T	521_I	0.609	0.66
169_E	211_R	0.608	0.66
320_H	329_R	0.608	0.66
297_I	300_V	0.607	0.66
296_E	301_S	0.607	0.66
133_K	349_T	0.606	0.65
82_Y	113_N	0.605	0.65
593_A	598_D	0.605	0.65
87_R	111_T	0.605	0.65
627_D	640_R	0.605	0.65
261_V	345_S	0.603	0.65
88_A	157_H	0.602	0.65
683_R	688_V	0.602	0.65
457_H	461_G	0.601	0.65
505_G	524_G	0.600	0.65
692_L	713_G	0.600	0.65
484_R	495_D	0.599	0.65
284_S	291_A	0.599	0.65
48_P	88_A	0.599	0.65
246_V	251_L	0.598	0.64
475_L	493_E	0.598	0.64
320_H	357_P	0.597	0.64
285_A	288_E	0.597	0.64
206_V	210_W	0.597	0.64
48_P	348_P	0.596	0.64
437_L	443_A	0.595	0.64
619_L	623_R	0.595	0.64
261_V	270_S	0.594	0.64
586_R	597_E	0.594	0.64
647_D	651_K	0.592	0.64
561_P	564_L	0.591	0.63
503_A	508_V	0.591	0.63
85_P	392_G	0.590	0.63
705_R	709_L	0.590	0.63
476_R	493_E	0.590	0.63
49_T	189_A	0.588	0.63
58_Q	256_S	0.588	0.63
501_A	518_A	0.587	0.63
26_Y	30_A	0.587	0.63
89_L	389_G	0.587	0.63
359_R	362_V	0.585	0.63
291_A	306_S	0.583	0.62
349_T	357_P	0.583	0.62
692_L	698_V	0.583	0.62
291_A	307_D	0.582	0.62
691_E	709_L	0.582	0.62
249_D	255_G	0.582	0.62
679_E	683_R	0.582	0.62
675_P	679_E	0.581	0.62
99_A	102_R	0.581	0.62
394_P	397_D	0.581	0.62
359_R	394_P	0.581	0.62
220_H	223_Q	0.579	0.62
132_E	392_G	0.578	0.62
165_G	333_E	0.577	0.62
286_E	290_L	0.577	0.62
703_R	711_N	0.577	0.62
688_V	692_L	0.576	0.62
562_T	575_D	0.575	0.61
169_E	173_A	0.575	0.61
320_H	347_T	0.575	0.61
583_S	600_L	0.575	0.61
563_P	566_L	0.575	0.61
362_V	667_G	0.574	0.61
702_G	709_L	0.574	0.61
496_G	525_L	0.573	0.61
355_N	396_L	0.573	0.61
324_L	389_G	0.573	0.61
83_I	131_S	0.572	0.61
457_H	460_L	0.571	0.61
132_E	358_A	0.571	0.61
489_N	498_A	0.570	0.61
358_A	386_Q	0.570	0.61
441_V	444_A	0.569	0.61
349_T	392_G	0.568	0.60
132_E	323_G	0.568	0.60
54_T	390_R	0.567	0.60
298_R	306_S	0.567	0.60
139_R	174_K	0.567	0.60
169_E	316_G	0.567	0.60
124_N	127_V	0.566	0.60
240_G	248_A	0.566	0.60
515_P	523_D	0.565	0.60
336_F	358_A	0.565	0.60
285_A	301_S	0.564	0.60
26_Y	47_V	0.564	0.60
244_A	255_G	0.564	0.60
517_S	528_A	0.563	0.60
633_D	636_R	0.562	0.60
93_K	387_M	0.562	0.60
49_T	350_L	0.562	0.60
159_V	377_Q	0.561	0.59
92_E	356_T	0.560	0.59
486_L	496_G	0.558	0.59
199_A	285_A	0.558	0.59
651_K	656_E	0.558	0.59
306_S	310_A	0.557	0.59
132_E	355_N	0.556	0.59
521_I	528_A	0.556	0.59
669_L	674_G	0.555	0.59
627_D	631_E	0.554	0.59
287_R	314_A	0.551	0.58
32_A	93_K	0.550	0.58
191_V	200_W	0.550	0.58
564_L	572_R	0.549	0.58
311_D	315_S	0.548	0.58
584_G	600_L	0.548	0.58
680_A	683_R	0.546	0.57
439_T	442_L	0.546	0.57
499_L	515_P	0.546	0.57
510_R	513_V	0.545	0.57
89_L	349_T	0.543	0.57
190_T	390_R	0.543	0.57
290_L	295_A	0.543	0.57
88_A	386_Q	0.542	0.57
284_S	290_L	0.542	0.57
285_A	297_I	0.541	0.57
507_L	518_A	0.541	0.57
111_T	397_D	0.541	0.57
634_E	638_A	0.540	0.57
680_A	684_V	0.540	0.57
504_T	513_V	0.539	0.56
654_T	657_W	0.539	0.56
584_G	591_E	0.538	0.56
650_G	653_E	0.537	0.56
26_Y	51_S	0.536	0.56
169_E	193_N	0.535	0.56
589_Y	604_T	0.535	0.56
279_G	343_A	0.535	0.56
251_L	343_A	0.535	0.56
453_E	494_R	0.534	0.56
46_S	381_V	0.534	0.56
83_I	171_T	0.534	0.56
113_N	329_R	0.533	0.56
239_S	250_T	0.533	0.56
135_D	138_V	0.533	0.56
166_P	201_L	0.533	0.56
613_E	622_A	0.533	0.56
424_P	428_R	0.532	0.56
132_E	357_P	0.532	0.56
453_E	462_G	0.532	0.56
631_E	692_L	0.531	0.55
242_Q	248_A	0.530	0.55
585_D	593_A	0.529	0.55
240_G	255_G	0.528	0.55
170_V	173_A	0.528	0.55
164_R	167_T	0.527	0.55
355_N	393_R	0.527	0.55
585_D	589_Y	0.527	0.55
504_T	521_I	0.526	0.55
491_F	495_D	0.526	0.55
506_Q	522_I	0.526	0.55
358_A	391_A	0.525	0.55
85_P	390_R	0.525	0.55
215_L	400_G	0.524	0.54
130_T	133_K	0.524	0.54
686_Y	691_E	0.523	0.54
499_L	513_V	0.523	0.54
621_T	624_L	0.522	0.54
487_D	495_D	0.522	0.54
189_A	357_P	0.522	0.54
469_T	477_S	0.522	0.54
302_D	310_A	0.521	0.54
518_A	524_G	0.521	0.54
492_V	595_E	0.521	0.54
349_T	356_T	0.521	0.54
92_E	133_K	0.520	0.54
288_E	311_D	0.520	0.54
696_A	710_Y	0.520	0.54
448_G	451_T	0.519	0.54
679_E	682_K	0.519	0.54
612_F	672_E	0.519	0.54
687_G	691_E	0.519	0.54
152_V	187_L	0.518	0.54
49_T	52_G	0.518	0.54
664_R	668_E	0.517	0.53
476_R	495_D	0.516	0.53
366_W	378_P	0.515	0.53
389_G	393_R	0.515	0.53
517_S	521_I	0.515	0.53
218_G	403_V	0.515	0.53
489_N	494_R	0.514	0.53
482_V	492_V	0.514	0.53
48_P	111_T	0.513	0.53
194_A	205_L	0.513	0.53
224_S	228_D	0.513	0.53
570_V	684_V	0.513	0.53
266_N	269_A	0.512	0.53
260_F	351_A	0.510	0.52
303_T	310_A	0.510	0.52
565_G	572_R	0.509	0.52
165_G	350_L	0.509	0.52
615_W	619_L	0.509	0.52
590_T	594_Y	0.508	0.52
44_V	191_V	0.507	0.52
510_R	524_G	0.507	0.52
322_A	392_G	0.507	0.52
418_R	423_D	0.506	0.52
595_E	598_D	0.505	0.52
316_G	321_H	0.505	0.52
86_L	349_T	0.504	0.52
284_S	288_E	0.504	0.52
167_T	170_V	0.504	0.52
627_D	643_V	0.504	0.52
521_I	573_T	0.504	0.52
701_V	708_R	0.503	0.51
90_A	128_V	0.503	0.51
49_T	400_G	0.502	0.51
489_N	500_R	0.502	0.51
616_L	619_L	0.502	0.51
576_M	592_V	0.502	0.51
450_T	455_G	0.501	0.51
288_E	295_A	0.501	0.51
505_G	525_L	0.500	0.51

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2zj8A	2	0.8863	100	0.292	Contact Map
2p6rA	1	0.8697	100	0.303	Contact Map
2va8A	1	0.8723	100	0.312	Contact Map
5agaA	4	0.9349	100	0.327	Contact Map
4f92B	1	0.9119	100	0.349	Contact Map
4bgdA	1	0.9055	100	0.384	Contact Map
4bujA	1	0.7957	100	0.448	Contact Map
4qu4A	1	0.8148	100	0.478	Contact Map
4u4cA	1	0.8442	100	0.482	Contact Map
4a4zA	1	0.8352	100	0.489	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0166 seconds.