UVRC - HALSA - GREMLIN Contacts

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UVRC - UvrABC system protein C

UniProt:	Q9HMU5	Sequences: MNGDEVRARASELPAEPGVYQFVARDPDGTADGERVLYVGKAVDIRDRVRSYGDPRSERIAGMVARADDVTVAVTDTETQALLLEANLVKRHQPRYNVRLKDDKSYPLVQVTSHREAPRIEVTRDPDPGAAAFGPYTDKGDVETVVKAVRSVYGLRGCSEHKYRDRERPCLDYEMGLCAAPCTGAISEREYREAVESATRFFEGETGALADPLRREMAAAAQAEAFERAANLRDRLAVVEGFHEGGGAAVAAGDADAGASTDVLGVAVEGDAATVARLHAEGGQLVERDQHRLEAPQGEDRVAAVLAAFLVQYYAERDLPERILLPEPHGDDEVAAWLDAADVAVGVPGAGREARLVELALKNAHRRAGGGDELGALADALGVRRPERIEGVDVSHAQGREVVGSNVCFVDGSAETADYRRKKLDEENDDYANMRRLVGWRAERAVDGRDDRPDPDVLLVDGGRGQLDAALDAVEAAGWDGPDAVIALAKDEEVVVTPDRTYDWGSDAPQLHVLQRVRDEAHRFAVAYHRTLRDDVTTALDGITGVGPELRARLLGRFGSVAGVRQASVKDLRDVAGVGEATAETIAKRL	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	590 (562)
Sequences:	3207 (1917)
Seq/√Len:	80.9

ECOLI - UVRC
BACSU - UVRC
HALSA - UVRC

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
116_E	188_E	4.619	1.00
15_A	44_D	4.575	1.00
584_E	588_K	4.243	1.00
13_L	49_V	4.037	1.00
225_A	228_R	4.031	1.00
415_E	418_D	3.885	1.00
187_S	190_E	3.468	1.00
216_E	232_L	3.433	1.00
423_K	532_L	3.433	1.00
26_D	35_R	3.314	1.00
435_R	472_D	3.228	1.00
564_V	572_L	3.193	1.00
541_D	551_R	3.159	1.00
64_V	67_A	3.116	1.00
410_V	415_E	3.058	1.00
36_V	92_H	2.924	1.00
578_V	586_I	2.905	1.00
131_A	199_T	2.805	1.00
214_R	240_E	2.731	1.00
488_L	514_L	2.650	1.00
29_G	69_D	2.585	1.00
423_K	528_Y	2.553	1.00
464_R	468_D	2.542	1.00
392_V	442_A	2.504	1.00
210_A	236_L	2.489	1.00
387_E	411_D	2.478	1.00
268_V	302_V	2.466	1.00
467_L	487_A	2.454	1.00
354_A	358_E	2.386	1.00
571_D	574_D	2.372	1.00
9_R	69_D	2.371	1.00
15_A	46_R	2.342	1.00
573_R	580_E	2.333	1.00
219_A	223_A	2.320	1.00
493_E	496_V	2.310	1.00
439_G	476_A	2.283	1.00
213_L	236_L	2.283	1.00
459_L	486_I	2.265	1.00
110_Q	130_A	2.245	1.00
580_E	584_E	2.239	1.00
27_P	68_D	2.169	1.00
563_G	566_Q	2.138	1.00
117_A	163_Y	2.137	1.00
230_A	234_D	2.130	1.00
214_R	218_A	2.106	1.00
569_V	573_R	2.071	1.00
220_A	232_L	2.056	1.00
494_V	497_T	2.035	1.00
111_V	120_I	2.017	1.00
431_Y	465_G	1.971	1.00
111_V	199_T	1.953	1.00
568_S	571_D	1.948	1.00
569_V	584_E	1.943	1.00
218_A	221_A	1.942	1.00
200_R	205_E	1.939	1.00
186_I	190_E	1.935	1.00
218_A	222_Q	1.934	1.00
468_D	471_L	1.925	1.00
562_A	566_Q	1.921	1.00
391_G	407_V	1.920	1.00
391_G	517_V	1.916	1.00
377_L	510_Q	1.913	1.00
122_V	143_E	1.908	1.00
528_Y	532_L	1.908	1.00
421_R	528_Y	1.907	1.00
537_T	542_G	1.878	1.00
375_G	378_A	1.860	1.00
493_E	498_P	1.850	1.00
60_I	63_M	1.849	1.00
442_A	458_L	1.843	1.00
216_E	228_R	1.841	1.00
210_A	240_E	1.827	1.00
438_V	473_A	1.824	1.00
471_L	485_V	1.819	1.00
402_V	433_N	1.817	1.00
215_R	219_A	1.817	1.00
37_L	95_R	1.800	1.00
169_P	183_T	1.777	1.00
435_R	476_A	1.766	1.00
546_V	582_T	1.764	1.00
37_L	59_R	1.759	1.00
396_H	428_N	1.752	1.00
544_T	585_T	1.745	1.00
36_V	39_V	1.739	1.00
190_E	193_E	1.728	1.00
76_D	247_G	1.726	1.00
228_R	232_L	1.719	1.00
265_G	326_P	1.709	1.00
16_E	74_V	1.701	1.00
392_V	438_V	1.691	1.00
431_Y	469_A	1.685	1.00
558_F	575_V	1.682	1.00
228_R	231_N	1.673	1.00
471_L	475_E	1.666	1.00
37_L	60_I	1.655	1.00
173_Y	180_A	1.653	1.00
392_V	406_N	1.645	1.00
114_H	130_A	1.631	1.00
188_E	192_R	1.629	1.00
15_A	47_D	1.625	1.00
326_P	361_L	1.619	1.00
397_A	529_H	1.609	1.00
192_R	196_E	1.605	1.00
63_M	67_A	1.587	1.00
265_G	361_L	1.587	1.00
44_D	47_D	1.584	1.00
579_G	582_T	1.584	1.00
473_A	477_A	1.573	1.00
51_S	54_D	1.555	1.00
390_E	441_R	1.554	1.00
443_E	447_D	1.553	1.00
332_D	335_A	1.553	1.00
394_V	404_G	1.548	1.00
307_A	331_D	1.541	0.99
557_R	575_V	1.528	0.99
267_A	365_H	1.525	0.99
26_D	66_R	1.522	0.99
405_S	524_F	1.521	0.99
582_T	586_I	1.515	0.99
458_L	474_V	1.512	0.99
180_A	185_A	1.511	0.99
385_R	456_D	1.509	0.99
391_G	521_A	1.502	0.99
489_A	496_V	1.498	0.99
212_P	216_E	1.496	0.99
550_L	582_T	1.487	0.99
515_Q	519_D	1.483	0.99
582_T	585_T	1.481	0.99
388_R	418_D	1.480	0.99
216_E	219_A	1.477	0.99
321_E	341_A	1.476	0.99
408_C	418_D	1.475	0.99
220_A	225_A	1.465	0.99
581_A	585_T	1.457	0.99
557_R	574_D	1.456	0.99
131_A	203_E	1.454	0.99
459_L	488_L	1.447	0.99
302_V	327_E	1.447	0.99
425_D	436_R	1.445	0.99
404_G	433_N	1.444	0.99
388_R	410_V	1.441	0.99
325_L	345_V	1.441	0.99
22_F	67_A	1.438	0.99
264_L	309_F	1.429	0.99
264_L	310_L	1.427	0.99
561_V	564_V	1.416	0.99
179_A	186_I	1.414	0.99
549_E	552_A	1.413	0.99
409_F	414_A	1.411	0.99
58_E	61_A	1.397	0.99
520_E	523_R	1.391	0.99
494_V	498_P	1.387	0.99
553_R	575_V	1.386	0.99
325_L	347_V	1.371	0.99
213_L	232_L	1.371	0.99
13_L	70_V	1.369	0.99
471_L	498_P	1.369	0.99
496_V	499_D	1.368	0.99
548_P	552_A	1.362	0.99
279_H	313_Y	1.361	0.99
435_R	473_A	1.357	0.99
546_V	586_I	1.355	0.99
264_L	277_R	1.353	0.99
578_V	582_T	1.350	0.99
404_G	437_L	1.344	0.99
59_R	63_M	1.336	0.99
405_S	521_A	1.336	0.99
529_H	533_R	1.335	0.99
278_L	288_R	1.335	0.99
469_A	473_A	1.331	0.98
193_E	196_E	1.330	0.98
376_A	510_Q	1.326	0.98
383_V	386_P	1.313	0.98
120_I	198_A	1.312	0.98
154_G	198_A	1.312	0.98
112_T	121_E	1.305	0.98
435_R	439_G	1.304	0.98
495_V	514_L	1.303	0.98
57_S	60_I	1.301	0.98
396_H	424_L	1.297	0.98
405_S	525_A	1.296	0.98
391_G	459_L	1.291	0.98
210_A	214_R	1.286	0.98
460_V	470_A	1.285	0.98
526_V	530_R	1.277	0.98
26_D	37_L	1.267	0.98
488_L	495_V	1.266	0.98
47_D	55_P	1.261	0.98
376_A	508_A	1.260	0.98
154_G	194_A	1.258	0.98
9_R	12_E	1.256	0.98
324_L	346_G	1.254	0.98
157_G	172_D	1.245	0.98
511_L	515_Q	1.240	0.98
47_D	50_R	1.235	0.98
211_D	214_R	1.232	0.97
397_A	534_D	1.231	0.97
493_E	497_T	1.230	0.97
86_A	105_S	1.227	0.97
395_S	526_V	1.222	0.97
350_A	353_E	1.220	0.97
439_G	473_A	1.218	0.97
396_H	402_V	1.215	0.97
306_L	326_P	1.215	0.97
274_T	292_R	1.212	0.97
429_D	435_R	1.211	0.97
352_R	355_R	1.211	0.97
237_A	240_E	1.210	0.97
438_V	470_A	1.205	0.97
429_D	432_A	1.202	0.97
324_L	357_V	1.200	0.97
151_S	177_L	1.198	0.97
445_A	452_R	1.192	0.97
301_R	304_A	1.182	0.97
7_R	11_S	1.179	0.97
373_E	510_Q	1.171	0.97
230_A	233_R	1.168	0.96
122_V	142_V	1.167	0.96
396_H	427_E	1.167	0.96
197_S	212_P	1.164	0.96
375_G	379_D	1.163	0.96
475_E	480_D	1.163	0.96
361_L	365_H	1.160	0.96
6_V	10_A	1.159	0.96
549_E	553_R	1.159	0.96
491_D	518_R	1.156	0.96
388_R	408_C	1.156	0.96
154_G	179_A	1.152	0.96
374_L	386_P	1.147	0.96
276_A	288_R	1.145	0.96
511_L	518_R	1.142	0.96
322_R	353_E	1.138	0.96
531_T	535_D	1.135	0.96
404_G	424_L	1.132	0.96
322_R	344_A	1.128	0.96
380_A	504_W	1.128	0.96
543_I	586_I	1.126	0.96
434_M	438_V	1.125	0.96
322_R	346_G	1.123	0.96
467_L	496_V	1.122	0.96
172_D	177_L	1.117	0.95
314_Y	320_P	1.114	0.95
10_A	13_L	1.112	0.95
133_F	199_T	1.108	0.95
424_L	433_N	1.107	0.95
389_I	517_V	1.107	0.95
403_V	532_L	1.107	0.95
303_A	327_E	1.097	0.95
392_V	458_L	1.094	0.95
489_A	494_V	1.089	0.95
109_V	120_I	1.085	0.95
397_A	401_E	1.080	0.95
358_E	361_L	1.071	0.94
170_C	178_C	1.067	0.94
459_L	514_L	1.067	0.94
220_A	228_R	1.063	0.94
378_A	386_P	1.063	0.94
117_A	188_E	1.062	0.94
394_V	405_S	1.061	0.94
426_E	429_D	1.060	0.94
510_Q	513_V	1.054	0.94
173_Y	185_A	1.054	0.94
422_K	444_R	1.045	0.94
170_C	182_C	1.043	0.93
218_A	224_E	1.041	0.93
155_L	198_A	1.039	0.93
117_A	184_G	1.033	0.93
179_A	194_A	1.032	0.93
421_R	531_T	1.032	0.93
310_L	323_I	1.030	0.93
373_E	513_V	1.027	0.93
123_T	126_P	1.023	0.93
71_T	288_R	1.023	0.93
123_T	130_A	1.022	0.93
474_V	485_V	1.022	0.93
489_A	493_E	1.022	0.93
355_R	358_E	1.021	0.93
263_V	280_A	1.020	0.93
389_I	457_V	1.019	0.93
515_Q	518_R	1.018	0.93
435_R	469_A	1.018	0.93
148_A	152_V	1.017	0.93
493_E	518_R	1.016	0.93
396_H	433_N	1.009	0.92
358_E	362_K	1.009	0.92
59_R	98_V	1.006	0.92
197_S	208_A	1.006	0.92
268_V	273_A	0.997	0.92
110_Q	128_P	0.997	0.92
278_L	360_A	0.995	0.92
489_A	518_R	0.995	0.92
277_R	313_Y	0.994	0.92
495_V	499_D	0.993	0.92
323_I	345_V	0.988	0.92
392_V	404_G	0.986	0.91
539_A	542_G	0.985	0.91
429_D	465_G	0.984	0.91
486_I	495_V	0.984	0.91
207_G	211_D	0.984	0.91
496_V	500_R	0.982	0.91
178_C	182_C	0.981	0.91
348_P	353_E	0.980	0.91
16_E	362_K	0.978	0.91
442_A	477_A	0.973	0.91
569_V	587_A	0.968	0.91
419_Y	520_E	0.966	0.91
446_V	477_A	0.966	0.91
474_V	479_W	0.963	0.90
554_L	564_V	0.962	0.90
392_V	437_L	0.961	0.90
569_V	580_E	0.959	0.90
325_L	329_H	0.956	0.90
398_Q	529_H	0.956	0.90
528_Y	531_T	0.952	0.90
66_R	96_Y	0.952	0.90
215_R	218_A	0.952	0.90
62_G	66_R	0.950	0.90
28_D	35_R	0.948	0.90
406_N	422_K	0.946	0.90
200_R	208_A	0.943	0.90
80_Q	246_G	0.942	0.89
113_S	199_T	0.941	0.89
494_V	501_T	0.938	0.89
550_L	553_R	0.938	0.89
362_K	365_H	0.936	0.89
78_E	82_L	0.935	0.89
21_Q	71_T	0.933	0.89
572_L	578_V	0.931	0.89
397_A	400_R	0.931	0.89
550_L	578_V	0.929	0.89
311_V	337_W	0.928	0.89
144_T	238_V	0.928	0.89
438_V	469_A	0.927	0.89
467_L	471_L	0.927	0.89
496_V	501_T	0.926	0.89
563_G	571_D	0.925	0.89
414_A	516_R	0.922	0.88
569_V	583_A	0.919	0.88
394_V	434_M	0.917	0.88
518_R	521_A	0.917	0.88
437_L	458_L	0.916	0.88
521_A	524_F	0.915	0.88
155_L	195_V	0.914	0.88
422_K	437_L	0.912	0.88
219_A	222_Q	0.910	0.88
498_P	501_T	0.909	0.88
186_I	194_A	0.908	0.88
491_D	494_V	0.908	0.88
585_T	588_K	0.907	0.88
439_G	443_E	0.902	0.87
221_A	224_E	0.902	0.87
10_A	50_R	0.901	0.87
438_V	460_V	0.900	0.87
117_A	179_A	0.899	0.87
329_H	332_D	0.897	0.87
377_L	514_L	0.895	0.87
497_T	500_R	0.894	0.87
493_E	501_T	0.894	0.87
552_A	556_G	0.894	0.87
328_P	332_D	0.893	0.87
22_F	70_V	0.893	0.87
550_L	579_G	0.892	0.87
410_V	418_D	0.892	0.87
196_E	199_T	0.891	0.87
459_L	517_V	0.886	0.86
450_D	454_D	0.881	0.86
497_T	501_T	0.879	0.86
475_E	478_G	0.878	0.86
120_I	149_V	0.877	0.86
13_L	45_I	0.876	0.86
148_A	239_V	0.876	0.86
257_A	261_T	0.871	0.85
265_G	364_A	0.868	0.85
150_R	157_G	0.867	0.85
21_Q	92_H	0.865	0.85
307_A	329_H	0.864	0.85
378_A	383_V	0.860	0.85
8_A	11_S	0.860	0.85
113_S	131_A	0.860	0.85
559_G	563_G	0.859	0.85
46_R	50_R	0.859	0.85
310_L	325_L	0.859	0.85
260_S	282_G	0.858	0.85
359_L	362_K	0.853	0.84
213_L	239_V	0.853	0.84
310_L	329_H	0.853	0.84
158_C	178_C	0.851	0.84
212_P	215_R	0.851	0.84
168_R	183_T	0.850	0.84
136_Y	202_F	0.849	0.84
265_G	357_V	0.848	0.84
311_V	334_V	0.847	0.84
568_S	574_D	0.845	0.84
14_P	44_D	0.844	0.84
260_S	283_G	0.841	0.83
128_P	132_A	0.839	0.83
57_S	61_A	0.839	0.83
391_G	526_V	0.837	0.83
87_N	249_A	0.836	0.83
575_V	578_V	0.833	0.83
166_R	183_T	0.832	0.83
401_E	532_L	0.830	0.83
56_R	61_A	0.830	0.83
154_G	176_G	0.830	0.83
59_R	62_G	0.829	0.82
491_D	515_Q	0.829	0.82
291_H	309_F	0.826	0.82
348_P	351_G	0.825	0.82
14_P	72_V	0.821	0.82
489_A	511_L	0.821	0.82
374_L	389_I	0.818	0.82
431_Y	468_D	0.814	0.81
392_V	434_M	0.813	0.81
76_D	362_K	0.812	0.81
583_A	586_I	0.810	0.81
389_I	459_L	0.808	0.81
538_T	541_D	0.807	0.81
309_F	313_Y	0.806	0.81
120_I	146_V	0.806	0.81
546_V	579_G	0.802	0.80
200_R	212_P	0.801	0.80
512_H	515_Q	0.801	0.80
324_L	348_P	0.801	0.80
494_V	499_D	0.801	0.80
87_N	286_V	0.801	0.80
194_A	197_S	0.799	0.80
491_D	511_L	0.799	0.80
261_T	322_R	0.797	0.80
278_L	285_L	0.796	0.80
491_D	521_A	0.793	0.80
434_M	470_A	0.791	0.79
332_D	345_V	0.790	0.79
376_A	379_D	0.788	0.79
110_Q	121_E	0.788	0.79
210_A	239_V	0.785	0.79
513_V	517_V	0.783	0.79
394_V	402_V	0.782	0.79
148_A	235_R	0.777	0.78
567_A	575_V	0.776	0.78
495_V	498_P	0.776	0.78
446_V	450_D	0.774	0.78
21_Q	39_V	0.772	0.78
161_H	164_R	0.771	0.78
403_V	528_Y	0.771	0.78
377_L	381_L	0.770	0.78
261_T	324_L	0.770	0.78
169_P	180_A	0.770	0.78
273_A	305_V	0.769	0.77
104_K	124_R	0.766	0.77
401_E	423_K	0.765	0.77
196_E	200_R	0.764	0.77
111_V	195_V	0.763	0.77
396_H	399_G	0.763	0.77
269_E	365_H	0.762	0.77
83_L	138_D	0.762	0.77
562_A	565_R	0.757	0.76
419_Y	523_R	0.754	0.76
21_Q	73_A	0.754	0.76
487_A	496_V	0.754	0.76
371_G	375_G	0.751	0.76
505_G	508_A	0.747	0.75
264_L	323_I	0.746	0.75
378_A	385_R	0.743	0.75
396_H	429_D	0.741	0.75
573_R	578_V	0.740	0.75
431_Y	491_D	0.738	0.75
442_A	474_V	0.738	0.75
263_V	324_L	0.736	0.74
114_H	129_G	0.736	0.74
334_V	338_L	0.734	0.74
156_R	181_P	0.733	0.74
307_A	330_G	0.733	0.74
512_H	516_R	0.731	0.74
49_V	70_V	0.730	0.74
538_T	551_R	0.730	0.74
142_V	146_V	0.730	0.74
522_H	526_V	0.729	0.74
553_R	556_G	0.728	0.74
471_L	499_D	0.726	0.73
173_Y	176_G	0.723	0.73
306_L	329_H	0.722	0.73
472_D	475_E	0.720	0.73
276_A	285_L	0.717	0.72
122_V	138_D	0.716	0.72
62_G	95_R	0.714	0.72
573_R	584_E	0.713	0.72
397_A	402_V	0.713	0.72
109_V	142_V	0.713	0.72
260_S	321_E	0.712	0.72
397_A	533_R	0.709	0.72
498_P	511_L	0.708	0.71
406_N	438_V	0.708	0.71
75_T	145_V	0.707	0.71
473_A	476_A	0.706	0.71
308_A	457_V	0.706	0.71
13_L	46_R	0.705	0.71
141_D	241_G	0.703	0.71
472_D	476_A	0.702	0.71
266_V	302_V	0.702	0.71
381_L	495_V	0.701	0.71
204_G	265_G	0.700	0.71
391_G	488_L	0.697	0.70
546_V	578_V	0.697	0.70
215_R	226_F	0.697	0.70
37_L	66_R	0.696	0.70
87_N	284_Q	0.696	0.70
121_E	159_S	0.693	0.70
86_A	90_K	0.692	0.70
431_Y	466_Q	0.691	0.70
92_H	285_L	0.690	0.69
436_R	440_W	0.690	0.69
150_R	172_D	0.688	0.69
11_S	586_I	0.688	0.69
543_I	546_V	0.688	0.69
73_A	288_R	0.687	0.69
162_K	165_D	0.686	0.69
211_D	215_R	0.686	0.69
493_E	499_D	0.685	0.69
445_A	450_D	0.684	0.69
76_D	359_L	0.684	0.69
335_A	339_D	0.683	0.69
468_D	499_D	0.683	0.69
406_N	458_L	0.683	0.69
15_A	50_R	0.681	0.68
37_L	502_Y	0.679	0.68
127_D	130_A	0.679	0.68
145_V	242_F	0.677	0.68
241_G	244_E	0.677	0.68
308_A	311_V	0.676	0.68
110_Q	129_G	0.676	0.68
460_V	473_A	0.675	0.68
466_Q	469_A	0.675	0.68
386_P	551_R	0.674	0.68
546_V	550_L	0.674	0.68
62_G	65_A	0.673	0.68
16_E	44_D	0.671	0.67
60_I	98_V	0.669	0.67
402_V	427_E	0.669	0.67
467_L	481_G	0.669	0.67
493_E	500_R	0.669	0.67
334_V	345_V	0.668	0.67
570_K	574_D	0.666	0.67
136_Y	404_G	0.665	0.67
236_L	240_E	0.662	0.66
391_G	405_S	0.662	0.66
335_A	344_A	0.662	0.66
509_P	512_H	0.661	0.66
9_R	13_L	0.661	0.66
14_P	18_G	0.660	0.66
112_T	128_P	0.659	0.66
90_K	104_K	0.659	0.66
570_K	573_R	0.658	0.66
114_H	160_E	0.658	0.66
329_H	334_V	0.657	0.66
172_D	179_A	0.657	0.66
166_R	169_P	0.657	0.66
530_R	533_R	0.657	0.66
9_R	70_V	0.655	0.65
488_L	492_E	0.655	0.65
80_Q	248_A	0.654	0.65
158_C	170_C	0.652	0.65
7_R	10_A	0.649	0.65
233_R	237_A	0.649	0.65
539_A	565_R	0.647	0.65
424_L	437_L	0.646	0.64
292_R	546_V	0.646	0.64
335_A	342_D	0.646	0.64
8_A	12_E	0.645	0.64
160_E	163_Y	0.644	0.64
488_L	518_R	0.642	0.64
558_F	567_A	0.641	0.64
572_L	575_V	0.640	0.64
6_V	49_V	0.639	0.64
109_V	146_V	0.639	0.64
494_V	500_R	0.636	0.63
218_A	226_F	0.634	0.63
195_V	198_A	0.633	0.63
122_V	139_K	0.631	0.63
163_Y	166_R	0.631	0.63
111_V	586_I	0.631	0.63
336_A	342_D	0.631	0.63
280_A	285_L	0.630	0.62
465_G	468_D	0.630	0.62
560_S	563_G	0.628	0.62
339_D	343_V	0.628	0.62
428_N	433_N	0.627	0.62
434_M	460_V	0.627	0.62
160_E	164_R	0.626	0.62
414_A	517_V	0.626	0.62
6_V	13_L	0.626	0.62
248_A	285_L	0.625	0.62
325_L	328_P	0.624	0.62
405_S	527_A	0.624	0.62
495_V	500_R	0.623	0.62
335_A	345_V	0.621	0.61
149_V	201_F	0.620	0.61
160_E	167_E	0.620	0.61
402_V	428_N	0.619	0.61
380_A	508_A	0.619	0.61
102_D	124_R	0.619	0.61
573_R	583_A	0.618	0.61
458_L	485_V	0.618	0.61
489_A	515_Q	0.618	0.61
322_R	350_A	0.617	0.61
467_L	498_P	0.616	0.61
560_S	572_L	0.616	0.61
460_V	487_A	0.616	0.61
432_A	473_A	0.616	0.61
570_K	580_E	0.615	0.61
16_E	76_D	0.614	0.61
432_A	435_R	0.613	0.60
35_R	92_H	0.613	0.60
439_G	477_A	0.611	0.60
572_L	587_A	0.611	0.60
303_A	330_G	0.610	0.60
149_V	198_A	0.610	0.60
146_V	150_R	0.609	0.60
113_S	195_V	0.609	0.60
120_I	195_V	0.608	0.60
158_C	182_C	0.608	0.60
467_L	518_R	0.608	0.60
377_L	513_V	0.607	0.60
101_K	105_S	0.606	0.60
240_E	243_H	0.605	0.59
506_S	509_P	0.604	0.59
406_N	441_R	0.603	0.59
156_R	399_G	0.603	0.59
14_P	20_Y	0.602	0.59
373_E	516_R	0.602	0.59
443_E	446_V	0.601	0.59
60_I	67_A	0.599	0.59
492_E	518_R	0.598	0.59
459_L	495_V	0.597	0.58
327_E	349_G	0.594	0.58
575_V	587_A	0.594	0.58
338_L	343_V	0.594	0.58
105_S	123_T	0.594	0.58
384_R	480_D	0.593	0.58
266_V	311_V	0.591	0.58
540_L	543_I	0.591	0.58
498_P	518_R	0.590	0.57
113_S	130_A	0.589	0.57
110_Q	132_A	0.589	0.57
444_R	450_D	0.588	0.57
496_V	518_R	0.588	0.57
568_S	587_A	0.587	0.57
545_G	585_T	0.587	0.57
442_A	479_W	0.585	0.57
217_M	233_R	0.583	0.57
505_G	510_Q	0.582	0.56
171_L	174_E	0.581	0.56
260_S	478_G	0.581	0.56
266_V	306_L	0.580	0.56
196_E	328_P	0.580	0.56
392_V	455_P	0.578	0.56
511_L	519_D	0.578	0.56
194_A	198_A	0.578	0.56
357_V	364_A	0.577	0.56
221_A	398_Q	0.577	0.56
401_E	529_H	0.576	0.56
336_A	339_D	0.576	0.56
193_E	197_S	0.575	0.56
391_G	518_R	0.575	0.56
62_G	96_Y	0.574	0.55
402_V	429_D	0.574	0.55
541_D	561_V	0.573	0.55
22_F	49_V	0.572	0.55
389_I	414_A	0.572	0.55
136_Y	199_T	0.572	0.55
558_F	572_L	0.572	0.55
199_T	203_E	0.572	0.55
96_Y	100_L	0.571	0.55
529_H	534_D	0.570	0.55
47_D	51_S	0.570	0.55
90_K	103_D	0.569	0.55
339_D	342_D	0.568	0.55
26_D	249_A	0.568	0.55
332_D	472_D	0.567	0.55
51_S	515_Q	0.566	0.54
267_A	364_A	0.565	0.54
59_R	92_H	0.564	0.54
329_H	347_V	0.564	0.54
333_E	336_A	0.564	0.54
162_K	172_D	0.562	0.54
264_L	299_E	0.562	0.54
435_R	470_A	0.562	0.54
402_V	426_E	0.562	0.54
266_V	326_P	0.561	0.54
497_T	502_Y	0.560	0.54
494_V	515_Q	0.559	0.53
35_R	315_A	0.559	0.53
553_R	577_G	0.559	0.53
86_A	100_L	0.558	0.53
6_V	9_R	0.557	0.53
140_G	144_T	0.556	0.53
222_Q	339_D	0.556	0.53
58_E	62_G	0.555	0.53
217_M	236_L	0.555	0.53
107_P	138_D	0.554	0.53
397_A	428_N	0.554	0.53
446_V	479_W	0.554	0.53
117_A	185_A	0.553	0.53
328_P	349_G	0.552	0.53
29_G	35_R	0.552	0.53
419_Y	524_F	0.552	0.53
495_V	502_Y	0.552	0.53
349_G	353_E	0.551	0.52
160_E	166_R	0.551	0.52
22_F	75_T	0.551	0.52
395_S	530_R	0.550	0.52
26_D	68_D	0.549	0.52
494_V	518_R	0.549	0.52
10_A	53_G	0.549	0.52
405_S	513_V	0.549	0.52
43_V	386_P	0.548	0.52
171_L	182_C	0.548	0.52
514_L	521_A	0.548	0.52
541_D	560_S	0.548	0.52
396_H	466_Q	0.548	0.52
516_R	519_D	0.547	0.52
218_A	223_A	0.547	0.52
303_A	328_P	0.547	0.52
471_L	480_D	0.546	0.52
27_P	188_E	0.546	0.52
88_L	92_H	0.546	0.52
414_A	419_Y	0.545	0.52
276_A	290_Q	0.545	0.52
67_A	70_V	0.545	0.52
573_R	587_A	0.545	0.52
76_D	80_Q	0.544	0.52
114_H	199_T	0.543	0.51
154_G	157_G	0.542	0.51
578_V	583_A	0.542	0.51
295_A	305_V	0.542	0.51
277_R	352_R	0.541	0.51
83_L	337_W	0.541	0.51
543_I	564_V	0.540	0.51
105_S	124_R	0.540	0.51
160_E	165_D	0.539	0.51
45_I	52_Y	0.539	0.51
226_F	296_P	0.538	0.51
126_P	136_Y	0.538	0.51
144_T	147_K	0.538	0.51
17_P	20_Y	0.537	0.51
386_P	489_A	0.537	0.51
80_Q	247_G	0.537	0.51
232_L	236_L	0.534	0.50
52_Y	60_I	0.533	0.50
389_I	458_L	0.533	0.50
35_R	95_R	0.533	0.50
310_L	574_D	0.533	0.50
399_G	402_V	0.531	0.50
442_A	454_D	0.531	0.50
225_A	344_A	0.531	0.50
399_G	529_H	0.531	0.50
50_R	60_I	0.529	0.50
63_M	92_H	0.528	0.49
398_Q	431_Y	0.527	0.49
350_A	354_A	0.527	0.49
217_M	232_L	0.527	0.49
553_R	578_V	0.526	0.49
147_K	177_L	0.526	0.49
460_V	518_R	0.525	0.49
113_S	196_E	0.525	0.49
14_P	74_V	0.525	0.49
208_A	236_L	0.525	0.49
428_N	431_Y	0.525	0.49
329_H	345_V	0.525	0.49
263_V	360_A	0.523	0.49
396_H	525_A	0.523	0.49
221_A	386_P	0.522	0.49
214_R	222_Q	0.522	0.49
396_H	487_A	0.522	0.49
36_V	101_K	0.522	0.49
250_V	352_R	0.521	0.49
439_G	469_A	0.521	0.49
45_I	310_L	0.520	0.48
519_D	522_H	0.520	0.48
581_A	584_E	0.520	0.48
50_R	54_D	0.520	0.48
260_S	318_D	0.520	0.48
563_G	574_D	0.520	0.48
496_V	521_A	0.520	0.48
208_A	211_D	0.519	0.48
63_M	69_D	0.519	0.48
407_V	414_A	0.519	0.48
163_Y	188_E	0.518	0.48
486_I	497_T	0.518	0.48
377_L	457_V	0.518	0.48
569_V	588_K	0.517	0.48
49_V	53_G	0.517	0.48
431_Y	434_M	0.516	0.48
246_G	313_Y	0.516	0.48
491_D	504_W	0.516	0.48
409_F	513_V	0.515	0.48
392_V	422_K	0.515	0.48
492_E	503_D	0.515	0.48
298_G	301_R	0.515	0.48
559_G	562_A	0.515	0.48
526_V	535_D	0.515	0.48
6_V	86_A	0.515	0.48
291_H	465_G	0.514	0.48
193_E	270_G	0.513	0.48
83_L	311_V	0.513	0.48
319_L	325_L	0.513	0.48
320_P	323_I	0.512	0.47
154_G	231_N	0.511	0.47
504_W	511_L	0.511	0.47
273_A	325_L	0.511	0.47
142_V	242_F	0.510	0.47
454_D	479_W	0.509	0.47
309_F	312_Q	0.509	0.47
215_R	342_D	0.509	0.47
37_L	50_R	0.509	0.47
224_E	237_A	0.509	0.47
112_T	148_A	0.509	0.47
200_R	209_L	0.509	0.47
175_M	285_L	0.508	0.47
49_V	348_P	0.508	0.47
431_Y	436_R	0.508	0.47
259_A	321_E	0.508	0.47
96_Y	198_A	0.508	0.47
80_Q	244_E	0.508	0.47
101_K	137_T	0.507	0.47
493_E	511_L	0.507	0.47
469_A	485_V	0.507	0.47
571_D	587_A	0.506	0.47
262_D	281_E	0.506	0.47
60_I	64_V	0.506	0.47
557_R	567_A	0.505	0.46
458_L	470_A	0.504	0.46
141_D	145_V	0.504	0.46
441_R	455_P	0.503	0.46
222_Q	457_V	0.503	0.46
298_G	305_V	0.503	0.46
306_L	502_Y	0.503	0.46
137_T	174_E	0.502	0.46
285_L	288_R	0.502	0.46
347_V	351_G	0.501	0.46
347_V	354_A	0.501	0.46
424_L	436_R	0.501	0.46
151_S	239_V	0.500	0.46
503_D	511_L	0.500	0.46

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3c65A	1	0.2492	100	0.653	Contact Map
2nrtA	1	0.361	100	0.654	Contact Map
2nrrA	1	0.2339	100	0.718	Contact Map
2bgwA	2	0.3492	100	0.837	Contact Map
1yd6A	5	0.1627	100	0.841	Contact Map
1yd0A	1	0.1508	100	0.848	Contact Map
2wshA	4	0.1525	100	0.854	Contact Map
3gocA	2	0.3542	100	0.855	Contact Map
2w36A	1	0.3458	100	0.866	Contact Map
4bxoB	1	0.2559	99.9	0.895	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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