Q9HMU1 - HALSA - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

Q9HMU1 - Uncharacterized protein

UniProt:	Q9HMU1	Sequences: MVHVVSVADERNRFESPSAGLAGDAWAEREHERAEAAVRETAAGLPDVVRTETAVIEGIPHEAIVAHAGDAGADVVVMGTHGRTGMDHYLVGSVAEKVVRTSPIPVLTVGIED	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	113 (104)
Sequences:	10360 (8488)
Seq/√Len:	832.3

ECOLI - USPG USPE USPF USPD USPC USPA
BACSU - NHAX YXIE
HALSA - Q9HMU1 Q9HPP5 Q9HHV8 Q9HNX9 Q9HRP5 Q9HMJ0 Q9HRD8 Q9HMI9 Q9HPQ8 Q9HP90 Q9HPF7 Q9HHX5 Q9HHY0
SULSO - Q97V57 Q97X90 Q97U40 Q7LXW4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
61_H	97_K	2.901	1.00
54_A	67_H	2.654	1.00
75_V	107_L	2.584	1.00
58_G	63_A	2.442	1.00
76_V	104_I	2.421	1.00
68_A	76_V	2.151	1.00
42_A	53_T	2.147	1.00
96_E	100_R	2.031	1.00
78_M	98_V	2.000	1.00
56_I	63_A	1.947	1.00
68_A	103_P	1.910	1.00
80_T	110_G	1.847	1.00
30_E	33_R	1.764	1.00
102_S	106_V	1.734	1.00
69_G	103_P	1.707	1.00
31_H	35_E	1.689	1.00
34_A	38_V	1.687	1.00
41_T	45_L	1.671	1.00
80_T	108_T	1.622	1.00
63_A	66_A	1.601	1.00
56_I	67_H	1.598	1.00
76_V	102_S	1.590	1.00
35_E	39_R	1.589	1.00
76_V	98_V	1.586	1.00
37_A	41_T	1.540	1.00
65_V	101_T	1.512	1.00
41_T	44_G	1.421	1.00
32_E	36_A	1.391	1.00
7_V	63_A	1.370	1.00
27_A	31_H	1.356	1.00
30_E	34_A	1.319	1.00
5_V	56_I	1.299	1.00
35_E	53_T	1.277	1.00
78_M	95_A	1.263	1.00
40_E	43_A	1.245	1.00
65_V	68_A	1.245	1.00
99_V	108_T	1.211	1.00
97_K	101_T	1.209	1.00
86_M	90_L	1.196	1.00
34_A	37_A	1.185	1.00
64_I	98_V	1.176	1.00
96_E	99_V	1.146	1.00
33_R	37_A	1.139	1.00
6_S	34_A	1.127	1.00
37_A	40_E	1.122	1.00
34_A	45_L	1.108	1.00
28_E	32_E	1.091	1.00
20_G	23_G	1.084	1.00
68_A	104_I	1.082	1.00
33_R	36_A	1.075	1.00
88_H	96_E	1.074	1.00
22_A	25_A	1.056	1.00
34_A	55_V	1.046	1.00
24_D	28_E	1.045	1.00
60_P	94_V	1.039	1.00
5_V	67_H	1.025	1.00
67_H	73_A	1.007	1.00
39_R	43_A	0.985	1.00
65_V	102_S	0.976	1.00
39_R	42_A	0.971	1.00
77_V	107_L	0.969	1.00
38_V	42_A	0.966	1.00
65_V	98_V	0.956	1.00
80_T	95_A	0.953	1.00
7_V	60_P	0.941	1.00
25_A	28_E	0.929	1.00
7_V	58_G	0.920	1.00
61_H	65_V	0.919	1.00
38_V	53_T	0.912	1.00
95_A	108_T	0.909	1.00
59_I	62_E	0.907	1.00
77_V	109_V	0.899	1.00
29_R	32_E	0.883	1.00
68_A	73_A	0.881	1.00
85_G	88_H	0.873	1.00
58_G	62_E	0.859	1.00
83_R	87_D	0.852	1.00
24_D	27_A	0.849	1.00
82_G	93_S	0.848	1.00
85_G	89_Y	0.848	1.00
23_G	26_W	0.846	1.00
82_G	91_V	0.842	1.00
80_T	90_L	0.840	1.00
40_E	44_G	0.824	1.00
32_E	35_E	0.823	1.00
4_V	38_V	0.815	1.00
63_A	67_H	0.809	1.00
91_V	95_A	0.808	1.00
82_G	85_G	0.799	1.00
9_D	12_N	0.795	1.00
79_G	109_V	0.793	1.00
58_G	66_A	0.787	1.00
99_V	106_V	0.771	1.00
81_H	95_A	0.756	1.00
28_E	31_H	0.754	1.00
8_A	57_E	0.751	1.00
61_H	98_V	0.728	1.00
80_T	83_R	0.725	1.00
10_E	14_F	0.718	1.00
86_M	89_Y	0.714	1.00
23_G	27_A	0.713	1.00
27_A	57_E	0.697	1.00
61_H	101_T	0.679	1.00
10_E	13_R	0.668	1.00
98_V	106_V	0.660	1.00
78_M	108_T	0.658	1.00
26_W	29_R	0.653	1.00
39_R	53_T	0.653	1.00
38_V	41_T	0.649	1.00
64_I	76_V	0.637	1.00
8_A	34_A	0.635	1.00
69_G	104_I	0.635	1.00
36_A	40_E	0.634	1.00
90_L	95_A	0.633	1.00
11_R	14_F	0.622	1.00
82_G	92_G	0.622	1.00
54_A	57_E	0.614	1.00
26_W	30_E	0.611	1.00
81_H	84_T	0.611	1.00
4_V	51_T	0.610	1.00
67_H	72_G	0.607	1.00
12_N	15_E	0.603	1.00
84_T	88_H	0.602	1.00
17_P	22_A	0.600	1.00
81_H	94_V	0.597	1.00
36_A	39_R	0.595	1.00
5_V	64_I	0.594	1.00
68_A	72_G	0.594	1.00
72_G	103_P	0.589	1.00
10_E	57_E	0.588	1.00
61_H	94_V	0.586	1.00
64_I	68_A	0.583	1.00
60_P	64_I	0.578	1.00
29_R	33_R	0.575	1.00
11_R	17_P	0.562	1.00
45_L	49_V	0.561	1.00
8_A	55_V	0.559	1.00
44_G	47_D	0.555	1.00
19_A	22_A	0.554	1.00
35_E	40_E	0.554	1.00
45_L	48_V	0.552	1.00
76_V	106_V	0.550	1.00
42_A	45_L	0.540	1.00
4_V	8_A	0.539	1.00
25_A	29_R	0.538	1.00
16_S	20_G	0.534	1.00
10_E	15_E	0.533	1.00
85_G	90_L	0.530	1.00
89_Y	108_T	0.523	1.00
10_E	27_A	0.521	1.00
4_V	53_T	0.518	1.00
9_D	14_F	0.513	1.00
94_V	98_V	0.509	1.00
7_V	10_E	0.506	1.00
45_L	51_T	0.503	1.00
83_R	90_L	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2gm3A	2	0.8584	99.7	0.243	Contact Map
2dumA	2	0.9735	99.7	0.252	Contact Map
5ahwA	4	0.9912	99.7	0.255	Contact Map
4wnyA	2	0.8407	99.7	0.262	Contact Map
3tnjA	2	0.8584	99.7	0.263	Contact Map
3s3tA	4	0.9646	99.7	0.264	Contact Map
3mt0A	1	0.8673	99.7	0.269	Contact Map
1mjhA	2	0.9558	99.7	0.27	Contact Map
1tq8A	4	0.8142	99.7	0.274	Contact Map
4r2kA	2	0.9823	99.6	0.285	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0061 seconds.